Gene knockout of the α6 subunit of the γ-aminobutyric acid type A receptor: Lack of effect on responses to ethanol, pentobarbital, and general anesthetics

Molecular Pharmacology

Volumn 51, Issue 4, 1997, Pages 588-596

  Homanics, Gregg E ^a,c   Ferguson, Carolyn ^a   Quinlan, Joseph J ^a   Daggett, Jodi ^a   Snyder, Kimberly ^a   Lagenaur, Carl ^a   Mi, Zhi Ping ^a   Wang, Xiao Hui ^b   Grayson, Dennis R ^b   Firestone, Leonard L ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b ALLEGHENY SINGER RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; ALCOHOL; ANESTHETIC AGENT; CHLORIDE CHANNEL; PENTOBARBITAL; RECEPTOR SUBUNIT; 4 AMINOBUTYRIC ACID A RECEPTOR; BENZODIAZEPINE RECEPTOR AFFECTING AGENT; ENFLURANE; HALOTHANE; INHALATION ANESTHETIC AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CYTOARCHITECTURE; DOSE RESPONSE; DRUG EFFECT; DRUG RECEPTOR BINDING; GENE DISRUPTION; GENERAL ANESTHESIA; MOTOR DYSFUNCTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ANIMAL; ANIMAL BEHAVIOR; C57BL MOUSE; CEREBELLUM; CYTOLOGY; FEMALE; GENE DELETION; GENETIC TRANSCRIPTION; GENETICS; MACROMOLECULE; MALE; METABOLISM; MOUSE MUTANT; PHYSIOLOGY; POLYMERASE CHAIN REACTION; RAT; ULTRASTRUCTURE;

ANESTHETICS, INHALATION; ANIMALS; BEHAVIOR, ANIMAL; CEREBELLUM; ENFLURANE; ETHANOL; FEMALE; GABA MODULATORS; GENE DELETION; HALOTHANE; MACROMOLECULAR SUBSTANCES; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PENTOBARBITAL; POLYMERASE CHAIN REACTION; RATS; RECEPTORS, GABA-A; TRANSCRIPTION, GENETIC;

EID: 0030615289     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.51.4.588     Document Type: Article

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