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Volumn 389, Issue 6647, 1997, Pages 183-186

Defective platelet activation in Gα(q)-deficient mice

Author keywords

[No Author keywords available]

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ADRENALIN; ARACHIDONIC ACID; CALCIMYCIN; COLLAGEN; GUANINE NUCLEOTIDE BINDING PROTEIN; PHORBOL 13 ACETATE 12 MYRISTATE; PHOSPHOLIPASE C; PROTEIN SUBUNIT; THROMBIN; THROMBOCYTE ACTIVATING FACTOR ANTAGONIST;

EID: 0030756508     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/38284     Document Type: Article
Times cited : (511)

References (30)
  • 1
    • 0024532116 scopus 로고
    • Molecular mechanisms of platelet activation
    • Siess, W. Molecular mechanisms of platelet activation. Physiol Rev, 69, 58-178 (1989).
    • (1989) Physiol Rev , vol.69 , pp. 58-178
    • Siess, W.1
  • 2
    • 0028302211 scopus 로고
    • Role of platelets in thrombosis and hemostasis
    • Packham, M. A. Role of platelets in thrombosis and hemostasis. Can. J. Physiol. Pharmacol. 72, 278- 284 (1994).
    • (1994) Can. J. Physiol. Pharmacol. , vol.72 , pp. 278-284
    • Packham, M.A.1
  • 3
    • 0004056975 scopus 로고
    • (eds Fozzard, H. A., Haber, E., Jennings, R. B., Katz, A. M. & Morgan, H. E.) (Raven, New York
    • Coller, B. S. in The Heart and Cardiovascular System (eds Fozzard, H. A., Haber, E., Jennings, R. B., Katz, A. M. & Morgan, H. E.) 219-273 (Raven, New York, 1992).
    • (1992) The Heart and Cardiovascular System , pp. 219-273
    • Coller, B.S.1
  • 5
    • 0025952271 scopus 로고
    • Pharmacological receptors on blood platelets
    • Hourani, S. M. & Cusack, N. J. Pharmacological receptors on blood platelets. Pharmacol Rev. 43, 243-298 (1991).
    • (1991) Pharmacol Rev. , vol.43 , pp. 243-298
    • Hourani, S.M.1    Cusack, N.J.2
  • 7
    • 0026782001 scopus 로고
    • The cloned platelet thrombin receptor couples to at least two distinct effectors to stimulate phosphoinositide hydrolysis and inhibit adenyl cyclase
    • Hung, D. T., Wong, Y. H., Vu, T. K. H. & Coughlin, S. R. The cloned platelet thrombin receptor couples to at least two distinct effectors to stimulate phosphoinositide hydrolysis and inhibit adenyl cyclase. J. Biol. Chem. 267, 20831-20834 (1992).
    • (1992) J. Biol. Chem. , vol.267 , pp. 20831-20834
    • Hung, D.T.1    Wong, Y.H.2    Vu, T.K.H.3    Coughlin, S.R.4
  • 10
    • 0028288293 scopus 로고
    • Receptors for ADP on human blood platelets
    • Hourani, S. M. O. & Hall, D. A. Receptors for ADP on human blood platelets. Trends Pharmacol Sci. 15, 103-108 (1994).
    • (1994) Trends Pharmacol Sci. , vol.15 , pp. 103-108
    • Hourani, S.M.O.1    Hall, D.A.2
  • 12
    • 0028860268 scopus 로고
    • Heterotrimeric G proteins: Organizers of transmembrane signals
    • Neer, E. J. Heterotrimeric G proteins: Organizers of transmembrane signals. Cell 80, 249-257 (1995).
    • (1995) Cell , vol.80 , pp. 249-257
    • Neer, E.J.1
  • 13
    • 0003747219 scopus 로고    scopus 로고
    • Decreased expression of phospholipase C-β2 isozyme in human platelets with impaired function
    • Lee, S. B. et al. Decreased expression of phospholipase C-β2 isozyme in human platelets with impaired function. Blood 88, 1684-1691 (1996).
    • (1996) Blood , vol.88 , pp. 1684-1691
    • Lee, S.B.1
  • 14
    • 0029884155 scopus 로고    scopus 로고
    • Differential translocation of phospholipase C isozymes to integrin-mediated cytoskeletal complexes in thrombin-stimulated human platelets
    • Banno, Y., Nakashima, S., Ohzawa, M. & Nozawa, Y. Differential translocation of phospholipase C isozymes to integrin-mediated cytoskeletal complexes in thrombin-stimulated human platelets. J. Biol. Chem. 271, 14989-14994 (1996).
    • (1996) J. Biol. Chem. , vol.271 , pp. 14989-14994
    • Banno, Y.1    Nakashima, S.2    Ohzawa, M.3    Nozawa, Y.4
  • 15
    • 0026676806 scopus 로고
    • Isozyme-selective stimulation of phospholipase C-β2 by G-protein βγ subunits
    • Camps, M. et al. Isozyme-selective stimulation of phospholipase C-β2 by G-protein βγ subunits. Nature 360, 684-686 (1992).
    • (1992) Nature , vol.360 , pp. 684-686
    • Camps, M.1
  • 16
    • 0026676807 scopus 로고
    • Subunits βγ of heterotrimeric G protein activate β2 isoform of phospholipase C
    • Katz, A., Wu, D. & Simon, M. I. Subunits βγ of heterotrimeric G protein activate β2 isoform of phospholipase C. Nature 360, 686-689 (1992).
    • (1992) Nature , vol.360 , pp. 686-689
    • Katz, A.1    Wu, D.2    Simon, M.I.3
  • 17
    • 0027418803 scopus 로고
    • Activation of phospholipase C isozymes by G protein βγ subunits
    • Park, D., Jhon, D. Y., Lee, C. W. & Rhee, S. G. Activation of phospholipase C isozymes by G protein βγ subunits. J. Biol. Chem. 268, 4573-4576 (1993).
    • (1993) J. Biol. Chem. , vol.268 , pp. 4573-4576
    • Park, D.1    Jhon, D.Y.2    Lee, C.W.3    Rhee, S.G.4
  • 18
    • 0027214868 scopus 로고
    • Regulation of phospholipase C by G proteins
    • Smrcka, A. V. & Sternweis, P. C. Regulation of phospholipase C by G proteins. J. Biol. Chem. 268, 9667-9674 (1993).
    • (1993) J. Biol. Chem. , vol.268 , pp. 9667-9674
    • Smrcka, A.V.1    Sternweis, P.C.2
  • 19
    • 0029936331 scopus 로고    scopus 로고
    • Regulation of phosphoinositide phospholipases by hormones, neurotransmitters, and other agonists linked to G proteins
    • Exton, J. H. Regulation of phosphoinositide phospholipases by hormones, neurotransmitters, and other agonists linked to G proteins. Annu. Rev. Pharmacol Toxicol. 36, 481-509 (1996).
    • (1996) Annu. Rev. Pharmacol Toxicol. , vol.36 , pp. 481-509
    • Exton, J.H.1
  • 20
    • 0027364417 scopus 로고
    • Distribution and relative levels of expression of the phosphoinositidase-C-linked G-proteins Gqα and G11α: Absence of G11α in human platelets and haemopoietically derived cell lines
    • Milligan, G., Mullaney, I. & McCallum, J. F. Distribution and relative levels of expression of the phosphoinositidase-C-linked G-proteins Gqα and G11α: absence of G11α in human platelets and haemopoietically derived cell lines. Biochim. Biophys. Acta 1179, 208-212 (1993).
    • (1993) Biochim. Biophys. Acta , vol.1179 , pp. 208-212
    • Milligan, G.1    Mullaney, I.2    McCallum, J.F.3
  • 24
    • 0028910771 scopus 로고
    • Cytoskeletal domains in the activated platelet
    • Bearer, E. L. Cytoskeletal domains in the activated platelet. Cell Motil. Cytoskel 30, 50-66 (1995).
    • (1995) Cell Motil. Cytoskel , vol.30 , pp. 50-66
    • Bearer, E.L.1
  • 25
    • 0029147959 scopus 로고
    • Resolution of spontaneous bleeding events but failure of pregnancy in fibrinogen- Deficient mice
    • Suh, T. T. et al. Resolution of spontaneous bleeding events but failure of pregnancy in fibrinogen- deficient mice. Genes Dev. 9, 2020-2033 (1995).
    • (1995) Genes Dev. , vol.9 , pp. 2020-2033
    • Suh, T.T.1
  • 26
    • 0028062915 scopus 로고
    • Treatment of myocardial infarction, unstable angina, and angina pectoris
    • McMurray, J. & Rankin, A. Treatment of myocardial infarction, unstable angina, and angina pectoris. Br. Med. J. 309, 1343-1350 (1994).
    • (1994) Br. Med. J. , vol.309 , pp. 1343-1350
    • McMurray, J.1    Rankin, A.2
  • 27
    • 0020582095 scopus 로고
    • Mouse antithrombotic assay: A simple method for the evaluation of antithrombotic agents in vivo. Potentiation of antithrombotic activity by ethyl alcohol
    • DiMinno, G. & Silver, M. J. Mouse antithrombotic assay: A simple method for the evaluation of antithrombotic agents in vivo. Potentiation of antithrombotic activity by ethyl alcohol. J. Pharmacol. Exp. Ther. 255, 57-60 (1983).
    • (1983) J. Pharmacol. Exp. Ther. , vol.255 , pp. 57-60
    • DiMinno, G.1    Silver, M.J.2
  • 29
    • 0010182172 scopus 로고
    • (eds Watson, S. P. & Auth, K. S.) (IRL, Oxford)
    • Sage, S. O. in Platelets, a Practical Approach (eds Watson, S. P. & Auth, K. S.) 67-90 (IRL, Oxford, 1995).
    • (1995) Platelets, a Practical Approach , pp. 67-90
    • Sage, S.O.1
  • 30
    • 0028261115 scopus 로고
    • Antiplatelet activity of nipecotamides in experimental thrombosis in mice
    • Lawrence, W. H., Howell, R. D. & Gollumudi, R. Antiplatelet activity of nipecotamides in experimental thrombosis in mice. J. Pharmacol. Sci. 83, 222-225 (1994).
    • (1994) J. Pharmacol. Sci. , vol.83 , pp. 222-225
    • Lawrence, W.H.1    Howell, R.D.2    Gollumudi, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.