Control of memory formation through regulated expression of a CaMKII transgene

Science

Volumn 274, Issue 5293, 1996, Pages 1678-1683

  Mayford, Mark ^a   Bach, Mary Elizabeth ^a   Huang, Yan You ^a   Wang, Lei ^a   Hawkins, Robert D ^a   Kandel, Eric R ^a  

^a Howard Hughes Medical Institute ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DOXYCYCLINE; PROTEIN KINASE (CALCIUM,CALMODULIN) II;

AMNESIA; AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COGNITION; CONDITIONING; CORPUS STRIATUM; FEAR; GENE EXPRESSION REGULATION; GENE FUNCTION; HIPPOCAMPUS; LONG TERM POTENTIATION; MEMORY; MEMORY CONSOLIDATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; SPATIAL MEMORY; TRANSGENE; TRANSGENIC MOUSE;

AMYGDALA; ANIMALS; BRAIN; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CONDITIONING (PSYCHOLOGY); CORPUS STRIATUM; DOXYCYCLINE; FEAR; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENES, REPORTER; HIPPOCAMPUS; LONG-TERM POTENTIATION; MAZE LEARNING; MEMORY; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NEURONAL PLASTICITY; PROMOTER REGIONS (GENETICS); PROSENCEPHALON; SIGNAL TRANSDUCTION; TRANSGENES;

ANIMALIA; MUS MUSCULUS;

EID: 0029807527     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.274.5293.1678     Document Type: Article

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48. We thank R. Axel and T. Jessell for critically reading this manuscript; J. Finkelstein for maintaining and genotyping the mice; R. Shin, V. Winder, and L. Varshavsky for help with behavioral experiments; C. Lam for help with figures; H. Ayers and I. Trumpet for typing the manuscript; and M. Osman for animal care. This research was supported by the Howard Hughes Medical Institute and the National Institute of Mental Health.