Targeted disruption of the melanocortin-4 receptor results in obesity in mice

Cell

Volumn 88, Issue 1, 1997, Pages 131-141

  Huszar, Dennis ^a   Lynch, Catherine A ^a   Fairchild Huntress, Victoria ^a   Dunmore, Judy H ^a   Fang, Qing ^a   Berkemeier, Lucy R ^a   Gu, Wei ^a   Kesterson, Robert A ^d   Boston, Bruce A ^b   Cone, Roger D ^d   Smith, Francoise J ^c   Campfield, L Arthur ^c   Burn, Paul ^c   Frank, Lee ^a  

^a MILLENNIUM PHARMACEUTICALS INC   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^c Hoffman La Roche Department of Metabolic Diseases   (United States)

^d NONE

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INSULIN; LEPTIN; MELANOCORTIN 4 RECEPTOR; MEMBRANE RECEPTOR; PROOPIOMELANOCORTIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; GENE TARGETING; HYPERGLYCEMIA; HYPERINSULINEMIA; HYPERPHAGIA; MALE; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; STEM CELL;

EID: 0030889192     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(00)81865-6     Document Type: Article

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