Versatile retrovirus vector systems for regulated gene expression in vitro and in vivo

Molecular Medicine

Volumn 3, Issue 7, 1997, Pages 466-476

  Lindemann, Dirk ^a,b   Patriquin, Edward ^a,c   Feng, Sandy ^a,c   Mulligan, Richard C ^a,c  

^a WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^b UNIVERSITY OF WÜRZBURG   (Germany)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS VECTOR;

ARTICLE; DNA BINDING; GENE EXPRESSION REGULATION; GENE INDUCTION; GENE INSERTION; GENETIC TRANSDUCTION; NONHUMAN; PLASMID; PRIORITY JOURNAL; RETROVIRUS; TRANSACTIVATION; VIRUS EXPRESSION; VIRUS GENOME;

EID: 0030868549     PISSN: 10761551     EISSN: None     Source Type: Journal    
DOI: 10.1007/bf03401693     Document Type: Article

References (28)

1. Gossen M, Bujard H. (1992) Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc. Natl. Acad. Sci. USA 89 12: 5547-5551.
2. Gossen M, Freundlieb S, Bender G, Müller G, Hillen W, Bujard H. (1995) Transcriptional Activation by Tetracyclines in Mammalian Cells. Science 268, 23. June 1995: 1766-1769.
3. Rivera V, Clackson T, Natesan S, Pollock R, Amara J, Keenan T, Magari S, Phillips T, Courage N, Cerasoli FJ, Holt D, Gilman M. (1996) A humanized system for pharmacologic control of gene expression [see comments]. Nat. Med. 2, 9: 1028-1032.
4. No D, Yao T, Evans R. (1996) Ecdysone-inducible gene expression in mammalian cells and transgenic mice. Proc. Natl. Acad. Sci. USA 93, 8: 3346-3351.
5. Hillen W, W.A. (1989) TetR-tetO Interaction. In Protein-Nucleic Acid Interaction, vol. 10. H.U. Saenger W, editor. Macmillan Press, London. 143-162.
6. Furth PA, St Onge L, Boger H, Gruss P, Gossen M, Kistner A, Bujard H, Hennighausen L. (1994) Temporal control of gene expression in transgenic mice by a tetracycline-responsive promoter. Proc. Natl. Acad. Sci. U.S.A. 91, 20: 9302-9306.
7. Gossen M, Bonin A, Freundlieb S, Bujard H. (1994) Inducible gene expression systems for higher eukaryotic cells. Curr. Opin. Biotechnol. 5, 5: 516-520.
8. Bueler H, Mulligan RC. (1996) Induction of antigen-specific tumor immunity by genetic and cellular vaccines against MAGE: enhanced tumor protection by coexpression of granulocyte-macrophage colony-stimulating factor and B7-1. Mol. Med. 2: 545-555.
9. Dranoff G, Jaffee E, Lazenby A, Golumbek P, Levitsky H, Brose K, Jackson V, Hamada H, Pardoll D, Mulligan RC. (1993) Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity. Proc. Natl. Acad. Sci. U.S.A. 90, 8: 3539-3543.
10. Riviere I, Brose K, Mulligan RC. (1995) Effects of retroviral vector design on expression of human adenosine deaminase in murine bone marrow transplant recipients engrafted with genetically modified cells. Proc. Natl. Acad. Sci. U.S.A. 92, 15: 6733-6737.
11. Cone RD, Weber-Benarous A, Baorto D, Mulligan RC. (1987) Regulated expression of a complete human beta-globin gene encoded by a transmissible retrovirus vector. Mol. Cell. Biol. 7, 2: 887-897.
12. Yu SF, von Ruden T, Kantoff PW, Garber C, Seiberg M, Ruther U, Anderson WF, Wagner EF, Gilboa E. (1986) Self-inactivating retroviral vectors designed for transfer of whole genes into mammalian cells. Proc. Natl. Acad. Sci. U.S.A. 83, 10: 3194-3198.
13. Yee JK, Moores JC, Jolly DJ, Wolff JA, Respess JG, Friedmann T. (1987) Gene expression from transcriptionally disabled retroviral vectors. Proc. Natl. Acad. Sci. U.S.A. 84, 15: 5197-5201.
14. Jang SK, Wimmer E. (1990) Cap-independent translation of encephalomyocarditis virus RNA: structural elements of the internal ribosomal entry site and involvement of a cellular 57-kD RNA-binding protein. Genes. Dev. 4, 9: 1560-1572.
15. Pear WS, Nolan GP, Scott ML, Baltimore D. (1993) Production of high-titer helper-free retroviruses by transient transfection. Proc. Natl. Acad. Sci. U.S.A. 90, 18: 8392-8396.
16. Yaffe D, Saxel O. (1977) Serial passaging and differentiation of myogenic cells isolated from dystrophic mouse muscle. Nature 270: 725-727.
17. Blau HM, Chiu CP, Webster C. (1983) Cytoplasmic Activation of Human Nuclear Genes in Stable Heterocaryons. Cell 32: 1171-1180.
18. Ackland-Berglund CE, Leib DA. (1995) Efficacy of tetracycline-controlled gene expression is influenced by cell type. Biotechniques 18, 2: 196-200.
19. Dhawan J, Pan LC, Pavlath GK, Travis MA, Lanctot AM, Blau HM. (1991) Systemic delivery of human growth hormone by injection of genetically engineered myoblasts [see comments]. Science 254, 5037: 1509-1512.
20. Hofmann A, Nolan GP, Blau HM. (1996) Rapid retroviral delivery of tetracycline-inducible genes in a single autoregulatory cassette. Proc. Natl. Acad. Sci. U.S.A. 93, May 1996: 5185-5190.
21. Hwang J, Scuric Z, Anderson W. (1996) Novel retroviral vector transferring a suicide gene and a selectable marker gene with enhanced gene expression by using a tetracycline-responsive expression system. J. Virol. 70, 11: 8138-8141.
22. Iida A, Chen S-T, Friedmann T, Yee J-K. (1996) Inducible Gene Expression by Retrovirus-Mediated Transfer of a Modified Tetracycline-Regulated System. J. Virol. 70, 9: 6054-6059.
23. Paulus W, Baur I, Boyce FM, Breakefield XO, Reeves SA. (1996) Self-contained, tetracycline-regulated retroviral vector system for gene delivery to mammalian cells. J. Virol. 70, 1: 62-67.
24. Ory D, Neugeboren B, Mulligan R. (1996) A stable human-derived packaging cell line for production of high titer retrovirus/vesicular stomatitis virus G pseudotypes. Proc. Natl. Acad. Sci. U.S.A. 93, 21: 11400-11406.
25. Yang Y, Vanin E, Whitt M, Fornerod M, Zwart R, Schneiderman R, Grosveld G, Nienhuis A. (1995) Inducible, high-level production of infectious murine leukemia retroviral vector particles pseudotyped with vesicular stomatitis virus G envelope protein. Hum. Gene. Ther. 6, 9: 1203-1213.
26. Naldini L, Blomer U, Gallay P, Ory D, Mulligan R, Gage FH, Verma IM, Trono D. (1996) In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector. Science 272, 5259: 263-267.
27. Martial JA, Hallewell RA, Baxter JD, Goodman HM. (1979) Human growth hormone: complementary DNA cloning and expression in bacteria. Science 205, 4406: 602-607.
28. Ferry N, Duplessis O, Houssin D, Danos O, Heard JM. (1991) Retroviral-mediated gene-transfer into hepatocytes in vivo. Proc. Natl. Acad. Sci. U.S.A. 88, 19: 8377-8381.