Age-dependent reduction of hippocampal LTP in mice lacking N-methyl-D-aspartate receptor ε1 subunit

Neuroscience Letters

Volumn 203, Issue 1, 1996, Pages 69-71

  Ito, Isao ^a   Sakimura, Kenji ^b   Mishina, Masayoshi ^c   Sugiyama, Hiroyuki ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b NIIGATA UNIVERSITY   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

Author keywords

Development; Gene targeting; Glutamate receptor; Hippocampus; Long term potentiation; N methyl D aspartic acid; Slice

Indexed keywords

6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; RECEPTOR SUBUNIT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN DEVELOPMENT; BRAIN SLICE; CONTROLLED STUDY; ELECTROPHYSIOLOGY; HIPPOCAMPUS; LONG TERM POTENTIATION; MOUSE; MUTANT; NONHUMAN; PRIORITY JOURNAL;

EID: 0030053773     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/0304-3940(95)12258-3     Document Type: Article

References (13)

1. Bliss, T.V.P. and Collingridge, G.L., A synaptic model of memory: long-term potentiation in the hippocampus, Nature, 361 (1993) 31-39.
2. Ikeda, K., Nagasawa, M., Mori, H., Araki, K., Sakimura, K., Watanabe, M., Inoue, Y. and Mishina, M., Cloning and expression of the ε4 subunit of the NMDA receptor channel, FEBS Lett., 313 (1992) 34-38.
3. Izumi, Y. and Zorumski, C.F., Developmental changes in the effects of metabotropic glutamate receptor antagonists on CA1 long-term potentiation in rat hippocampal slices, Neurosci. Lett., 176 (1994) 89-92.
4. Kutsuwada, T., Kashiwabuchi, N., Mori, H., Sakimura, K., Kushiya, E., Araki, K., Meguro, H., Masaki, H., Kumanishi, T., Arakawa, M. and Mishina, M., Molecular diversity of the NMDA receptor channel, Nature, 358 (1992) 36-41.
5. Lowry, O.H., Rosenbrough, N., Fair, A.L. and Randall, R.J., Protein measurement with the Folin phenol reagent, J. Biol. Chem., 193 (1951) 265-275.
6. Meguro, H., Mori, H., Araki, K., Kushiya, E., Kutsuwada, T., Yamazaki, M., Kumanishi, T., Arakawa, M., Sakimura, K. and Mishina, M., Functional characterization of a heteromeric NMDA receptor channel expressed from cloned cDNAs, Nature, 357 (1992) 70-74.
7. Monyer, H., Burnashev, N., Laurie, D.J., Sakmann, B. and Seeburg, P.H., Developmental and regional expression in the rat brain and functional properties of four NMDA receptors, Neuron, 12 (1994) 529-540.
8. Monyer, H., Sprengel, R., Schoepfer, R., Herb, A., Higuchi, M., Lomeli, H., Burnashev, N., Sakmann, B. and Seeburg, P.H., Heteromeric NMDA receptors: molecular and functional distinction of subtypes, Science, 256 (1992) 1217-1221.
9. Moriyoshi, K., Masu, M., Ishii, T., Shigemoto, R., Mizuno, N. and Nakanishi, S., Molecular cloning and characterization of the rat NMDA receptor, Nature, 354 (1991) 31-37.
10. Sakimura, K., Kutsuwada, T., Ito, I., Manabe, T., Takayama, C., Kushiya, E., Yagi, T., Aizawa, S., Inoue, Y., Sugiyama, H. and Mishina, M., Reduced hippocampal LTP and spatial learning in mice lacking NMDA receptor ε1 subunit, Nature, 373 (1995) 151-155.
11. Watanabe, M., Inoue, Y., Sakimura, K. and Mishina, M., Developmental changes in distribution of NMDA receptor channel subunit mRNAs, NeuroReport, 3 (1992) 1138-1140.
12. Watanabe, M., Inoue, Y., Sakimura, K. and Mishina, M., Distinct distributions of five N-methyl-D-aspartate receptor channel subunit mRNAs in the forebrain, J. Comp. Neurol., 338 (1993) 377-390.
13. Yamazaki, M., Mori, H., Araki, K., Mori, K.J. and Mishina, M., Cloning, expression and modulation of mouse NMDA receptor subunit, FEBS Lett., 300 (1992) 39-45.