Attenuation of the obesity syndrome of ob/ob mice by the loss of neuropeptide Y

Science

Volumn 274, Issue 5293, 1996, Pages 1704-1707

  Erickson, Jay C ^a   Hollopeter, Gunther ^a   Palmiter, Richard D ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LEPTIN; NEUROPEPTIDE Y;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; ENERGY BALANCE; ENERGY EXPENDITURE; FEEDING BEHAVIOR; FOOD INTAKE; GENE EXPRESSION REGULATION; GENETIC DISORDER; HORMONE RELEASE; MOUSE; NEUROMODULATION; NONHUMAN; OBESITY; PRIORITY JOURNAL;

ADIPOSE TISSUE; ANIMALS; BLOOD GLUCOSE; BODY COMPOSITION; BODY HEIGHT; BODY WEIGHT; DIABETES MELLITUS; DIABETES MELLITUS, TYPE 2; EATING; ENERGY METABOLISM; FEMALE; FERTILITY; INSULIN-LIKE GROWTH FACTOR I; LEPTIN; MALE; MICE; MICE, MUTANT STRAINS; MICE, OBESE; NEUROPEPTIDE Y; OBESITY; OXYGEN CONSUMPTION; PROTEINS; RNA, MESSENGER;

ANIMALIA;

EID: 0029804743     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.274.5293.1704     Document Type: Article

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39. Special thanks to E. Shankland and M. Kushmerick for MRIs and spectra; G. Froelick for histology; the laboratory of S. Woods for help with indirect calorimetry; the Metabolism Laboratory of the Puget Sound Veterans Affairs Medical Center for serum insulin and glucose determinations; and M. Schwartz and D. Cummings for discussion and suggestions. J.C.E. is a Merck fellow.