Endoplasmic reticulum proteostasis impairment in aging

Aging Cell

Volumn 16, Issue 4, 2017, Pages 615-623

  Martínez, Gabriela ^a,b,c,d   Duran Aniotz, Claudia ^a,b,c   Cabral Miranda, Felipe ^a,b,c,e   Vivar, Juan P ^a,b,c   Hetz, Claudio ^a,b,c,f,g  

^a Universidad de Chile and Geroscience Center for Brain Health and Metabolism   (Chile)

^b UNIVERSITY OF CHILE   (Chile)

^c UNIVERSITY OF CHILE   (Chile)

^d UNIVERSIDAD MAYOR   (Chile)

^e FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^f BUCK INSTITUTE FOR RESEARCH ON AGING   (United States)

^g HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

aging; endoplasmic reticulum; endoplasmic reticulum stress; protein misfolding disorders; unfolded protein response

Indexed keywords

CELL DEATH; COGNITIVE AGING; DEGENERATIVE DISEASE; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; HOMEOSTASIS; HUMAN; NERVE DEGENERATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN HOMEOSTASIS; REVIEW; RISK FACTOR; UNFOLDED PROTEIN RESPONSE; AGING; ANALOGS AND DERIVATIVES; ANIMAL; BRAIN; CAENORHABDITIS ELEGANS; DROSOPHILA MELANOGASTER; DRUG EFFECTS; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; NERVE CELL; PATHOLOGY; PROTEOSTASIS DEFICIENCY; SACCHAROMYCES CEREVISIAE;

7-METHYL-5-(1-((3-(TRIFLUOROMETHYL)PHENYL)ACETYL)-2,3-DIHYDRO-1H-INDOL-5-YL)-7H-PYRROLO(2,3-D)PYRIMIDIN-4-AMINE; ADENINE; GSK2656157; GUANABENZ; INDOLE DERIVATIVE; PROTECTIVE AGENT; PROTEOME;

ADENINE; AGING; ANIMALS; BRAIN; CAENORHABDITIS ELEGANS; DROSOPHILA MELANOGASTER; ENDOPLASMIC RETICULUM STRESS; GUANABENZ; HUMANS; INDOLES; NEURODEGENERATIVE DISEASES; NEURONS; PROTECTIVE AGENTS; PROTEOME; PROTEOSTASIS; PROTEOSTASIS DEFICIENCIES; SACCHAROMYCES CEREVISIAE; UNFOLDED PROTEIN RESPONSE;

EID: 85018635685     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/acel.12599     Document Type: Review

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