Lifespan Extension Conferred by Endoplasmic Reticulum Secretory Pathway Deficiency Requires Induction of the Unfolded Protein Response

PLoS Genetics

Volumn 10, Issue 1, 2014, Pages

  Labunskyy, Vyacheslav M ^a   Gerashchenko, Maxim V ^a   Delaney, Joe R ^b   Kaya, Alaattin ^a   Kennedy, Brian K ^c,d   Kaeberlein, Matt ^b   Gladyshev, Vadim N ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^d BUCK INSTITUTE FOR RESEARCH ON AGING   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FUNGAL PROTEIN; IRE1P PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BIOGENESIS; CELL WALL; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; FUNGAL REPRODUCTION; FUNGUS MUTANT; GENE DELETION; GENE SEQUENCE; GENE TARGETING; GENETIC ASSOCIATION; LIFE EXTENSION; NONHUMAN; PROTEIN DEGRADATION; PROTEIN FOLDING; QUANTITATIVE ANALYSIS; RIBOSOME; SIGNAL TRANSDUCTION; UNFOLDED PROTEIN RESPONSE; UPREGULATION;

AGING; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; HUMANS; LONGEVITY; MEMBRANE GLYCOPROTEINS; MUTATION; PROTEIN FOLDING; PROTEIN-SERINE-THREONINE KINASES; RIBOSOMES; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SECRETORY PATHWAY; SIGNAL TRANSDUCTION; UNFOLDED PROTEIN RESPONSE;

EID: 84896726774     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1004019     Document Type: Article

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