Late-onset of spinal neurodegeneration in knock-in mice expressing a mutant BIP

PLoS ONE

Volumn 9, Issue 11, 2014, Pages

  Jin, Hisayo ^a   Mimura, Naoya ^a   Kashio, Makiko ^a   Koseki, Haruhiko ^b   Aoe, Tomohiko ^a,c  

^a CHIBA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b RIKEN Center for Integrative Medical Sciences   (Japan)

^c TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE; GLUCOSE REGULATED PROTEIN 94; KDEL RECEPTOR; RECEPTOR; UNCLASSIFIED DRUG; HEAT SHOCK PROTEIN; MOLECULAR CHAPERONE GRP78; TUNICAMYCIN;

AGING; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; AUTOPHAGY; CONTROLLED STUDY; CYTOPLASM; ENDOPLASMIC RETICULUM STRESS; HELA CELL LINE; MOTOR DYSFUNCTION; MOUSE; NERVE DEGENERATION; NONHUMAN; PROTEIN AGGREGATION; SPINAL CORD MOTONEURON; SPINAL CORD VENTRAL HORN; UBIQUITINATION; AGE; ANIMAL; DEGENERATIVE DISEASE; FLUORESCENCE MICROSCOPY; GENE TARGETING; GENETICS; HISTOLOGY; HUMAN; LATE ONSET DISORDER; METABOLISM; MOTONEURON; MUTATION; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; WESTERN BLOTTING;

MUS;

AGE FACTORS; ANIMALS; BLOTTING, WESTERN; ENDOPLASMIC RETICULUM STRESS; GENE KNOCK-IN TECHNIQUES; HEAT-SHOCK PROTEINS; HELA CELLS; HISTOLOGICAL TECHNIQUES; HUMANS; LATE ONSET DISORDERS; MICE; MICROSCOPY, FLUORESCENCE; MOTOR NEURONS; MUTATION; NEURODEGENERATIVE DISEASES; RECEPTORS, PEPTIDE; TUNICAMYCIN;

EID: 84911925193     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0112837     Document Type: Article

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