-
1
-
-
84898921541
-
Roles of eIF2alpha kinases in the pathogenesis of Alzheimer’s disease
-
PID: 24795560
-
Ohno M (2014) Roles of eIF2alpha kinases in the pathogenesis of Alzheimer’s disease. Front Mol Neurosci 7:22. doi:10.3389/fnmol.2014.00022
-
(2014)
Front Mol Neurosci
, vol.7
, pp. 22
-
-
Ohno, M.1
-
2
-
-
1642555780
-
Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: evidence for augmentation of a 42-specific gamma secretase
-
COI: 1:CAS:528:DC%2BD2cXmsVKj, PID: 14645205
-
Jankowsky JL, Fadale DJ, Anderson J, Xu GM, Gonzales V, Jenkins NA, Copeland NG, Lee MK, Younkin LH, Wagner SL, Younkin SG, Borchelt DR (2004) Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: evidence for augmentation of a 42-specific gamma secretase. Hum Mol Genet 13(2):159–170. doi:10.1093/hmg/ddh019
-
(2004)
Hum Mol Genet
, vol.13
, Issue.2
, pp. 159-170
-
-
Jankowsky, J.L.1
Fadale, D.J.2
Anderson, J.3
Xu, G.M.4
Gonzales, V.5
Jenkins, N.A.6
Copeland, N.G.7
Lee, M.K.8
Younkin, L.H.9
Wagner, S.L.10
Younkin, S.G.11
Borchelt, D.R.12
-
3
-
-
84907343347
-
Axonally synthesized ATF4 transmits a neurodegenerative signal across brain regions
-
COI: 1:CAS:528:DC%2BC2cXhsV2jtLjM, PID: 25171414
-
Baleriola J, Walker CA, Jean YY, Crary JF, Troy CM, Nagy PL, Hengst U (2014) Axonally synthesized ATF4 transmits a neurodegenerative signal across brain regions. Cell 158(5):1159–1172. doi:10.1016/j.cell.2014.07.001
-
(2014)
Cell
, vol.158
, Issue.5
, pp. 1159-1172
-
-
Baleriola, J.1
Walker, C.A.2
Jean, Y.Y.3
Crary, J.F.4
Troy, C.M.5
Nagy, P.L.6
Hengst, U.7
-
4
-
-
33845311194
-
ATF4 regulates gamma-secretase activity during amino acid imbalance
-
COI: 1:CAS:528:DC%2BD28Xhtleis73J, PID: 17141186
-
Mitsuda T, Hayakawa Y, Itoh M, Ohta K, Nakagawa T (2007) ATF4 regulates gamma-secretase activity during amino acid imbalance. Biochem Biophys Res Commun 352(3):722–727. doi:10.1016/j.bbrc.2006.11.075
-
(2007)
Biochem Biophys Res Commun
, vol.352
, Issue.3
, pp. 722-727
-
-
Mitsuda, T.1
Hayakawa, Y.2
Itoh, M.3
Ohta, K.4
Nakagawa, T.5
-
5
-
-
0042521291
-
Inducible enhancement of memory storage and synaptic plasticity in transgenic mice expressing an inhibitor of ATF4 (CREB-2) and C/EBP proteins
-
COI: 1:CAS:528:DC%2BD3sXmslOmu7w%3D, PID: 12925279
-
Chen A, Muzzio IA, Malleret G, Bartsch D, Verbitsky M, Pavlidis P, Yonan AL, Vronskaya S, Grody MB, Cepeda I, Gilliam TC, Kandel ER (2003) Inducible enhancement of memory storage and synaptic plasticity in transgenic mice expressing an inhibitor of ATF4 (CREB-2) and C/EBP proteins. Neuron 39(4):655–669. doi:10.1016/S0896-6273(03)00501-4
-
(2003)
Neuron
, vol.39
, Issue.4
, pp. 655-669
-
-
Chen, A.1
Muzzio, I.A.2
Malleret, G.3
Bartsch, D.4
Verbitsky, M.5
Pavlidis, P.6
Yonan, A.L.7
Vronskaya, S.8
Grody, M.B.9
Cepeda, I.10
Gilliam, T.C.11
Kandel, E.R.12
-
6
-
-
0026661584
-
Control of transcription factors by signal transduction pathways: the beginning of the end
-
COI: 1:CAS:528:DyaK38XmtlSksrs%3D, PID: 1455510
-
Karin M, Smeal T (1992) Control of transcription factors by signal transduction pathways: the beginning of the end. Trends Biochem Sci 17(10):418–422
-
(1992)
Trends Biochem Sci
, vol.17
, Issue.10
, pp. 418-422
-
-
Karin, M.1
Smeal, T.2
-
7
-
-
0025878233
-
Cross-family dimerization of transcription factors Fos/Jun and ATF/CREB alters DNA binding specificity
-
COI: 1:CAS:528:DyaK3MXktVahurw%3D, PID: 1827203
-
Hai T, Curran T (1991) Cross-family dimerization of transcription factors Fos/Jun and ATF/CREB alters DNA binding specificity. Proc Natl Acad Sci USA 88(9):3720–3724
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, Issue.9
, pp. 3720-3724
-
-
Hai, T.1
Curran, T.2
-
8
-
-
0026445510
-
ACR1, a yeast ATF/CREB repressor
-
COI: 1:CAS:528:DyaK3sXltFShsrw%3D, PID: 1448073
-
Vincent AC, Struhl K (1992) ACR1, a yeast ATF/CREB repressor. Mol Cell Biol 12(12):5394–5405
-
(1992)
Mol Cell Biol
, vol.12
, Issue.12
, pp. 5394-5405
-
-
Vincent, A.C.1
Struhl, K.2
-
9
-
-
84879381412
-
Internal ribosome entry site-mediated translational regulation of ATF4 splice variant in mammalian unfolded protein response
-
COI: 1:CAS:528:DC%2BC3sXhtFSmu7vE, PID: 23665047
-
Chan CP, Kok KH, Tang HM, Wong CM, Jin DY (2013) Internal ribosome entry site-mediated translational regulation of ATF4 splice variant in mammalian unfolded protein response. Biochim Biophys Acta 1833(10):2165–2175. doi:10.1016/j.bbamcr.2013.05.002
-
(2013)
Biochim Biophys Acta
, vol.1833
, Issue.10
, pp. 2165-2175
-
-
Chan, C.P.1
Kok, K.H.2
Tang, H.M.3
Wong, C.M.4
Jin, D.Y.5
-
10
-
-
3843117589
-
Reinitiation involving upstream ORFs regulates ATF4 mRNA translation in mammalian cells
-
COI: 1:CAS:528:DC%2BD2cXmvVKgt7o%3D, PID: 15277680
-
Vattem KM, Wek RC (2004) Reinitiation involving upstream ORFs regulates ATF4 mRNA translation in mammalian cells. Proc Natl Acad Sci USA 101(31):11269–11274. doi:10.1073/pnas.0400541101
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, Issue.31
, pp. 11269-11274
-
-
Vattem, K.M.1
Wek, R.C.2
-
11
-
-
0037353039
-
An integrated stress response regulates amino acid metabolism and resistance to oxidative stress
-
COI: 1:CAS:528:DC%2BD3sXjtVWkt74%3D, PID: 12667446
-
Harding HP, Zhang Y, Zeng H, Novoa I, Lu PD, Calfon M, Sadri N, Yun C, Popko B, Paules R, Stojdl DF, Bell JC, Hettmann T, Leiden JM, Ron D (2003) An integrated stress response regulates amino acid metabolism and resistance to oxidative stress. Mol Cell 11(3):619–633
-
(2003)
Mol Cell
, vol.11
, Issue.3
, pp. 619-633
-
-
Harding, H.P.1
Zhang, Y.2
Zeng, H.3
Novoa, I.4
Lu, P.D.5
Calfon, M.6
Sadri, N.7
Yun, C.8
Popko, B.9
Paules, R.10
Stojdl, D.F.11
Bell, J.C.12
Hettmann, T.13
Leiden, J.M.14
Ron, D.15
-
12
-
-
0033634654
-
Regulated translation initiation controls stress-induced gene expression in mammalian cells
-
COI: 1:CAS:528:DC%2BD3cXosV2mtrs%3D, PID: 11106749
-
Harding HP, Novoa I, Zhang Y, Zeng H, Wek R, Schapira M, Ron D (2000) Regulated translation initiation controls stress-induced gene expression in mammalian cells. Mol Cell 6(5):1099–1108
-
(2000)
Mol Cell
, vol.6
, Issue.5
, pp. 1099-1108
-
-
Harding, H.P.1
Novoa, I.2
Zhang, Y.3
Zeng, H.4
Wek, R.5
Schapira, M.6
Ron, D.7
-
13
-
-
84873287971
-
ATF4 protects against neuronal death in cellular Parkinson’s disease models by maintaining levels of parkin
-
COI: 1:CAS:528:DC%2BC3sXhtlOjsrvE, PID: 23392669
-
Sun X, Liu J, Crary JF, Malagelada C, Sulzer D, Greene LA, Levy OA (2013) ATF4 protects against neuronal death in cellular Parkinson’s disease models by maintaining levels of parkin. J Neurosci 33(6):2398–2407. doi:10.1523/JNEUROSCI. 2292-12.2013
-
(2013)
J Neurosci
, vol.33
, Issue.6
, pp. 2398-2407
-
-
Sun, X.1
Liu, J.2
Crary, J.F.3
Malagelada, C.4
Sulzer, D.5
Greene, L.A.6
Levy, O.A.7
-
14
-
-
84862952481
-
4-Phenylbutyric acid regulates collagen synthesis and secretion induced by high concentrations of glucose in human gingival fibroblasts
-
COI: 1:CAS:528:DC%2BC38XitFChtbY%3D, PID: 22359472
-
Lee GH, Oh HW, Lim HD, Lee W, Chae HJ, Kim HR (2011) 4-Phenylbutyric acid regulates collagen synthesis and secretion induced by high concentrations of glucose in human gingival fibroblasts. Korean J Physiol Pharmacol 15(6):345–351. doi:10.4196/kjpp.2011.15.6.345
-
(2011)
Korean J Physiol Pharmacol
, vol.15
, Issue.6
, pp. 345-351
-
-
Lee, G.H.1
Oh, H.W.2
Lim, H.D.3
Lee, W.4
Chae, H.J.5
Kim, H.R.6
-
15
-
-
34948868346
-
The p300/CBP-associated factor (PCAF) is a cofactor of ATF4 for amino acid-regulated transcription of CHOP
-
COI: 1:CAS:528:DC%2BD2sXhtFWhsr3M, PID: 17726049
-
Cherasse Y, Maurin AC, Chaveroux C, Jousse C, Carraro V, Parry L, Deval C, Chambon C, Fafournoux P, Bruhat A (2007) The p300/CBP-associated factor (PCAF) is a cofactor of ATF4 for amino acid-regulated transcription of CHOP. Nucleic Acids Res 35(17):5954–5965. doi:10.1093/nar/gkm642
-
(2007)
Nucleic Acids Res
, vol.35
, Issue.17
, pp. 5954-5965
-
-
Cherasse, Y.1
Maurin, A.C.2
Chaveroux, C.3
Jousse, C.4
Carraro, V.5
Parry, L.6
Deval, C.7
Chambon, C.8
Fafournoux, P.9
Bruhat, A.10
-
16
-
-
18544396997
-
Mouse NIPK interacts with ATF4 and affects its transcriptional activity
-
COI: 1:CAS:528:DC%2BD3sXjs1eqtrc%3D, PID: 12749859
-
Ord D, Ord T (2003) Mouse NIPK interacts with ATF4 and affects its transcriptional activity. Exp Cell Res 286(2):308–320
-
(2003)
Exp Cell Res
, vol.286
, Issue.2
, pp. 308-320
-
-
Ord, D.1
Ord, T.2
-
17
-
-
36348936212
-
Oxygen-dependent ATF-4 stability is mediated by the PHD3 oxygen sensor
-
PID: 17684156
-
Koditz J, Nesper J, Wottawa M, Stiehl DP, Camenisch G, Franke C, Myllyharju J, Wenger RH, Katschinski DM (2007) Oxygen-dependent ATF-4 stability is mediated by the PHD3 oxygen sensor. Blood 110(10):3610–3617. doi:10.1182/blood-2007-06-094441
-
(2007)
Blood
, vol.110
, Issue.10
, pp. 3610-3617
-
-
Koditz, J.1
Nesper, J.2
Wottawa, M.3
Stiehl, D.P.4
Camenisch, G.5
Franke, C.6
Myllyharju, J.7
Wenger, R.H.8
Katschinski, D.M.9
-
18
-
-
37849054321
-
Transfer-NMR and docking studies identify the binding of the peptide derived from activating transcription factor 4 to protein ubiquitin ligase beta-TrCP. competition STD-NMR with beta-catenin
-
COI: 1:CAS:528:DC%2BD2sXhtlygsr3P, PID: 18052253
-
Pons J, Evrard-Todeschi N, Bertho G, Gharbi-Benarous J, Tanchou V, Benarous R, Girault JP (2008) Transfer-NMR and docking studies identify the binding of the peptide derived from activating transcription factor 4 to protein ubiquitin ligase beta-TrCP. competition STD-NMR with beta-catenin. Biochemistry 47(1):14–29. doi:10.1021/bi7014212
-
(2008)
Biochemistry
, vol.47
, Issue.1
, pp. 14-29
-
-
Pons, J.1
Evrard-Todeschi, N.2
Bertho, G.3
Gharbi-Benarous, J.4
Tanchou, V.5
Benarous, R.6
Girault, J.P.7
-
19
-
-
84867301032
-
ATF4 interacts with Abro1/KIAA0157 scaffold protein and participates in a cytoprotective pathway
-
COI: 1:CAS:528:DC%2BC38Xhs1ajtrnF, PID: 22974638
-
Ambivero CT, Cilenti L, Zervos AS (2012) ATF4 interacts with Abro1/KIAA0157 scaffold protein and participates in a cytoprotective pathway. Biochim Biophys Acta 1823(12):2149–2156. doi:10.1016/j.bbamcr.2012.08.020
-
(2012)
Biochim Biophys Acta
, vol.1823
, Issue.12
, pp. 2149-2156
-
-
Ambivero, C.T.1
Cilenti, L.2
Zervos, A.S.3
-
20
-
-
79952401003
-
New modularity of DAP-kinases: alternative splicing of the DRP-1 gene produces a ZIPk-like isoform
-
COI: 1:CAS:528:DC%2BC3MXjsFGktrc%3D, PID: 21408167
-
Shoval Y, Berissi H, Kimchi A, Pietrokovski S (2011) New modularity of DAP-kinases: alternative splicing of the DRP-1 gene produces a ZIPk-like isoform. PLoS ONE 6(2):e17344. doi:10.1371/journal.pone.0017344
-
(2011)
PLoS ONE
, vol.6
, Issue.2
, pp. e17344
-
-
Shoval, Y.1
Berissi, H.2
Kimchi, A.3
Pietrokovski, S.4
-
21
-
-
33744536200
-
SATB2 is a multifunctional determinant of craniofacial patterning and osteoblast differentiation
-
COI: 1:CAS:528:DC%2BD28Xls1Shtrg%3D, PID: 16751105
-
Dobreva G, Chahrour M, Dautzenberg M, Chirivella L, Kanzler B, Farinas I, Karsenty G, Grosschedl R (2006) SATB2 is a multifunctional determinant of craniofacial patterning and osteoblast differentiation. Cell 125(5):971–986. doi:10.1016/j.cell.2006.05.012
-
(2006)
Cell
, vol.125
, Issue.5
, pp. 971-986
-
-
Dobreva, G.1
Chahrour, M.2
Dautzenberg, M.3
Chirivella, L.4
Kanzler, B.5
Farinas, I.6
Karsenty, G.7
Grosschedl, R.8
-
22
-
-
77950684784
-
FIAT, the factor-inhibiting ATF4-mediated transcription, also represses the transcriptional activity of the bZIP factor FRA-1
-
COI: 1:CAS:528:DC%2BC3cXmsVSrtbY%3D, PID: 20392257
-
St-Arnaud R, Mandic V, Elchaarani B (2010) FIAT, the factor-inhibiting ATF4-mediated transcription, also represses the transcriptional activity of the bZIP factor FRA-1. Ann N Y Acad Sci 1192:338–343. doi:10.1111/j.1749-6632.2009.05211.x
-
(2010)
Ann N Y Acad Sci
, vol.1192
, pp. 338-343
-
-
St-Arnaud, R.1
Mandic, V.2
Elchaarani, B.3
-
23
-
-
84862662817
-
Transcriptional repression of ATF4 gene by CCAAT/enhancer-binding protein beta (C/EBPbeta) differentially regulates integrated stress response
-
COI: 1:CAS:528:DC%2BC38XptVWrtL8%3D, PID: 22556424
-
Dey S, Savant S, Teske BF, Hatzoglou M, Calkhoven CF, Wek RC (2012) Transcriptional repression of ATF4 gene by CCAAT/enhancer-binding protein beta (C/EBPbeta) differentially regulates integrated stress response. J Biol Chem 287(26):21936–21949. doi:10.1074/jbc.M112.351783
-
(2012)
J Biol Chem
, vol.287
, Issue.26
, pp. 21936-21949
-
-
Dey, S.1
Savant, S.2
Teske, B.F.3
Hatzoglou, M.4
Calkhoven, C.F.5
Wek, R.C.6
-
24
-
-
0035877643
-
Identification of activating transcription factor 4 (ATF4) as an Nrf2-interacting protein. Implication for heme oxygenase-1 gene regulation
-
COI: 1:CAS:528:DC%2BD3MXksFGlsrc%3D, PID: 11274184
-
He CH, Gong P, Hu B, Stewart D, Choi ME, Choi AM, Alam J (2001) Identification of activating transcription factor 4 (ATF4) as an Nrf2-interacting protein. Implication for heme oxygenase-1 gene regulation. J Biol Chem 276(24):20858–20865. doi:10.1074/jbc.M101198200
-
(2001)
J Biol Chem
, vol.276
, Issue.24
, pp. 20858-20865
-
-
He, C.H.1
Gong, P.2
Hu, B.3
Stewart, D.4
Choi, M.E.5
Choi, A.M.6
Alam, J.7
-
25
-
-
84885635128
-
Post-translational regulation of gene expression using the ATF4 oxygen-dependent degradation domain for hypoxia-specific gene therapy
-
COI: 1:CAS:528:DC%2BC3sXhsFynsLfL, PID: 23952904
-
Cho SH, Oh B, Kim HA, Park JH, Lee M (2013) Post-translational regulation of gene expression using the ATF4 oxygen-dependent degradation domain for hypoxia-specific gene therapy. J Drug Target 21(9):830–836. doi:10.3109/1061186X.2013.829073
-
(2013)
J Drug Target
, vol.21
, Issue.9
, pp. 830-836
-
-
Cho, S.H.1
Oh, B.2
Kim, H.A.3
Park, J.H.4
Lee, M.5
-
26
-
-
57649245230
-
Phosphorylation of the translation initiation factor eIF2alpha increases BACE1 levels and promotes amyloidogenesis
-
PID: 19109907
-
O’Connor T, Sadleir KR, Maus E, Velliquette RA, Zhao J, Cole SL, Eimer WA, Hitt B, Bembinster LA, Lammich S, Lichtenthaler SF, Hebert SS, De Strooper B, Haass C, Bennett DA, Vassar R (2008) Phosphorylation of the translation initiation factor eIF2alpha increases BACE1 levels and promotes amyloidogenesis. Neuron 60(6):988–1009. doi:10.1016/j.neuron.2008.10.047
-
(2008)
Neuron
, vol.60
, Issue.6
, pp. 988-1009
-
-
O’Connor, T.1
Sadleir, K.R.2
Maus, E.3
Velliquette, R.A.4
Zhao, J.5
Cole, S.L.6
Eimer, W.A.7
Hitt, B.8
Bembinster, L.A.9
Lammich, S.10
Lichtenthaler, S.F.11
Hebert, S.S.12
De Strooper, B.13
Haass, C.14
Bennett, D.A.15
Vassar, R.16
-
27
-
-
84903814520
-
PERK mediates eIF2alpha phosphorylation responsible for BACE1 elevation, CREB dysfunction and neurodegeneration in a mouse model of Alzheimer’s disease
-
COI: 1:CAS:528:DC%2BC2cXhtVWrsr3N, PID: 24889041
-
Devi L, Ohno M (2014) PERK mediates eIF2alpha phosphorylation responsible for BACE1 elevation, CREB dysfunction and neurodegeneration in a mouse model of Alzheimer’s disease. Neurobiol Aging 35(10):2272–2281. doi:10.1016/j.neurobiolaging.2014.04.031
-
(2014)
Neurobiol Aging
, vol.35
, Issue.10
, pp. 2272-2281
-
-
Devi, L.1
Ohno, M.2
-
28
-
-
84885398154
-
Deletion of the eIF2alpha kinase GCN2 fails to rescue the memory decline associated with Alzheimer’s disease
-
COI: 1:CAS:528:DC%2BC3sXhs1Kiu7jK, PID: 24146979
-
Devi L, Ohno M (2013) Deletion of the eIF2alpha kinase GCN2 fails to rescue the memory decline associated with Alzheimer’s disease. PLoS ONE 8(10):e77335. doi:10.1371/journal.pone.0077335
-
(2013)
PLoS ONE
, vol.8
, Issue.10
, pp. e77335
-
-
Devi, L.1
Ohno, M.2
-
29
-
-
77953726485
-
Autophagy impairment stimulates PS1 expression and gamma-secretase activity
-
COI: 1:CAS:528:DC%2BC3cXpt1WjtLg%3D, PID: 20168091
-
Ohta K, Mizuno A, Ueda M, Li S, Suzuki Y, Hida Y, Hayakawa-Yano Y, Itoh M, Ohta E, Kobori M, Nakagawa T (2010) Autophagy impairment stimulates PS1 expression and gamma-secretase activity. Autophagy 6(3):345–352
-
(2010)
Autophagy
, vol.6
, Issue.3
, pp. 345-352
-
-
Ohta, K.1
Mizuno, A.2
Ueda, M.3
Li, S.4
Suzuki, Y.5
Hida, Y.6
Hayakawa-Yano, Y.7
Itoh, M.8
Ohta, E.9
Kobori, M.10
Nakagawa, T.11
-
30
-
-
84898733006
-
Tau acts as a mediator for Alzheimer’s disease-related synaptic deficits
-
PID: 24712999
-
Liao D, Miller EC, Teravskis PJ (2014) Tau acts as a mediator for Alzheimer’s disease-related synaptic deficits. Eur J Neurosci 39(7):1202–1213. doi:10.1111/ejn.12504
-
(2014)
Eur J Neurosci
, vol.39
, Issue.7
, pp. 1202-1213
-
-
Liao, D.1
Miller, E.C.2
Teravskis, P.J.3
-
31
-
-
80053212816
-
The role of tau in Alzheimer’s disease and related disorders
-
COI: 1:CAS:528:DC%2BC3MXhtlOntL%2FF, PID: 20553310
-
Medeiros R, Baglietto-Vargas D, LaFerla FM (2011) The role of tau in Alzheimer’s disease and related disorders. CNS Neurosci Ther 17(5):514–524. doi:10.1111/j.1755-5949.2010.00177.x
-
(2011)
CNS Neurosci Ther
, vol.17
, Issue.5
, pp. 514-524
-
-
Medeiros, R.1
Baglietto-Vargas, D.2
LaFerla, F.M.3
-
32
-
-
70349226800
-
The transcription factor ATF4 regulates glucose metabolism in mice through its expression in osteoblasts
-
COI: 1:CAS:528:DC%2BD1MXhtFWgs7%2FJ, PID: 19726872
-
Yoshizawa T, Hinoi E, Jung DY, Kajimura D, Ferron M, Seo J, Graff JM, Kim JK, Karsenty G (2009) The transcription factor ATF4 regulates glucose metabolism in mice through its expression in osteoblasts. J Clin Investig 119(9):2807–2817. doi:10.1172/JCI39366
-
(2009)
J Clin Investig
, vol.119
, Issue.9
, pp. 2807-2817
-
-
Yoshizawa, T.1
Hinoi, E.2
Jung, D.Y.3
Kajimura, D.4
Ferron, M.5
Seo, J.6
Graff, J.M.7
Kim, J.K.8
Karsenty, G.9
-
33
-
-
0041315834
-
Delineation of a negative feedback regulatory loop that controls protein translation during endoplasmic reticulum stress
-
COI: 1:CAS:528:DC%2BD3sXntVWqsb8%3D, PID: 12840028
-
Ma Y, Hendershot LM (2003) Delineation of a negative feedback regulatory loop that controls protein translation during endoplasmic reticulum stress. J Biol Chem 278(37):34864–34873. doi:10.1074/jbc.M301107200
-
(2003)
J Biol Chem
, vol.278
, Issue.37
, pp. 34864-34873
-
-
Ma, Y.1
Hendershot, L.M.2
-
34
-
-
84857385877
-
Protein phosphatase 1 subunit Ppp1r15a/GADD34 regulates cytokine production in polyinosinic:polycytidylic acid-stimulated dendritic cells
-
COI: 1:CAS:528:DC%2BC38Xjs1Wmt7w%3D, PID: 22315398
-
Clavarino G, Claudio N, Dalet A, Terawaki S, Couderc T, Chasson L, Ceppi M, Schmidt EK, Wenger T, Lecuit M, Gatti E, Pierre P (2012) Protein phosphatase 1 subunit Ppp1r15a/GADD34 regulates cytokine production in polyinosinic:polycytidylic acid-stimulated dendritic cells. Proc Natl Acad Sci USA 109(8):3006–3011. doi:10.1073/pnas.1104491109
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, Issue.8
, pp. 3006-3011
-
-
Clavarino, G.1
Claudio, N.2
Dalet, A.3
Terawaki, S.4
Couderc, T.5
Chasson, L.6
Ceppi, M.7
Schmidt, E.K.8
Wenger, T.9
Lecuit, M.10
Gatti, E.11
Pierre, P.12
-
35
-
-
77951150250
-
Neuronal death in Alzheimer’s disease and therapeutic opportunities
-
COI: 1:CAS:528:DC%2BC3cXkvFGjs70%3D, PID: 19725918
-
Donev R, Kolev M, Millet B, Thome J (2009) Neuronal death in Alzheimer’s disease and therapeutic opportunities. J Cell Mol Med 13(11–12):4329–4348. doi:10.1111/j.1582-4934.2009.00889.x
-
(2009)
J Cell Mol Med
, vol.13
, Issue.11-12
, pp. 4329-4348
-
-
Donev, R.1
Kolev, M.2
Millet, B.3
Thome, J.4
-
36
-
-
0033016172
-
Increased vulnerability of hippocampal neurons to excitotoxic necrosis in presenilin-1 mutant knock-in mice
-
COI: 1:CAS:528:DyaK1MXmtFOgsQ%3D%3D, PID: 9883847
-
Guo Q, Fu W, Sopher BL, Miller MW, Ware CB, Martin GM, Mattson MP (1999) Increased vulnerability of hippocampal neurons to excitotoxic necrosis in presenilin-1 mutant knock-in mice. Nat Med 5(1):101–106. doi:10.1038/4789
-
(1999)
Nat Med
, vol.5
, Issue.1
, pp. 101-106
-
-
Guo, Q.1
Fu, W.2
Sopher, B.L.3
Miller, M.W.4
Ware, C.B.5
Martin, G.M.6
Mattson, M.P.7
-
37
-
-
0034853813
-
Ultrastructure evidence of necrotic neural cell death in familial Alzheimer’s disease brains bearing presenilin-1 E280A mutation
-
PID: 12214045
-
Velez-Pardo C, Arroyave ST, Lopera F, Castano AD, Jimenez Del Rio M (2001) Ultrastructure evidence of necrotic neural cell death in familial Alzheimer’s disease brains bearing presenilin-1 E280A mutation. J Alzheimers Dis 3(4):409–415
-
(2001)
J Alzheimers Dis
, vol.3
, Issue.4
, pp. 409-415
-
-
Velez-Pardo, C.1
Arroyave, S.T.2
Lopera, F.3
Castano, A.D.4
Jimenez Del Rio, M.5
-
38
-
-
79959261693
-
Regulation of cell survival mechanisms in Alzheimer’s disease by glycogen synthase kinase-3
-
PID: 21629713
-
Mines MA, Beurel E, Jope RS (2011) Regulation of cell survival mechanisms in Alzheimer’s disease by glycogen synthase kinase-3. Int J Alzheimers Dis 2011:861072. doi:10.4061/2011/861072
-
(2011)
Int J Alzheimers Dis
, vol.2011
, pp. 861072
-
-
Mines, M.A.1
Beurel, E.2
Jope, R.S.3
-
39
-
-
84870984470
-
PERK is required at the ER-mitochondrial contact sites to convey apoptosis after ROS-based ER stress
-
COI: 1:CAS:528:DC%2BC38XhsVOhsLvK, PID: 22705852
-
Verfaillie T, Rubio N, Garg AD, Bultynck G, Rizzuto R, Decuypere JP, Piette J, Linehan C, Gupta S, Samali A, Agostinis P (2012) PERK is required at the ER-mitochondrial contact sites to convey apoptosis after ROS-based ER stress. Cell Death Differ 19(11):1880–1891. doi:10.1038/Cdd.2012.74
-
(2012)
Cell Death Differ
, vol.19
, Issue.11
, pp. 1880-1891
-
-
Verfaillie, T.1
Rubio, N.2
Garg, A.D.3
Bultynck, G.4
Rizzuto, R.5
Decuypere, J.P.6
Piette, J.7
Linehan, C.8
Gupta, S.9
Samali, A.10
Agostinis, P.11
-
40
-
-
78650412221
-
Neuronal apoptosis induced by endoplasmic reticulum stress is regulated by ATF4-CHOP-mediated induction of the Bcl-2 homology 3-only member PUMA
-
COI: 1:CAS:528:DC%2BC3cXhs1SlsbrF, PID: 21159964
-
Galehdar Z, Swan P, Fuerth B, Callaghan SM, Park DS, Cregan SP (2010) Neuronal apoptosis induced by endoplasmic reticulum stress is regulated by ATF4-CHOP-mediated induction of the Bcl-2 homology 3-only member PUMA. J Neurosci 30(50):16938–16948. doi:10.1523/Jneurosci.1598-10
-
(2010)
J Neurosci
, vol.30
, Issue.50
, pp. 16938-16948
-
-
Galehdar, Z.1
Swan, P.2
Fuerth, B.3
Callaghan, S.M.4
Park, D.S.5
Cregan, S.P.6
-
41
-
-
77952425214
-
TRB3 function in cardiac endoplasmic reticulum stress
-
COI: 1:CAS:528:DC%2BC3cXmtVSmsr4%3D, PID: 20360254
-
Avery J, Etzion S, DeBosch BJ, Jin XH, Lupu TS, Beitinjaneh B, Grand J, Kovacs A, Sambandam N, Muslin AJ (2010) TRB3 function in cardiac endoplasmic reticulum stress. Circ Res 106(9):1516–U1160. doi:10.1161/Circresaha.109.211920
-
(2010)
Circ Res
, vol.106
, Issue.9
, pp. 1160-1516
-
-
Avery, J.1
Etzion, S.2
DeBosch, B.J.3
Jin, X.H.4
Lupu, T.S.5
Beitinjaneh, B.6
Grand, J.7
Kovacs, A.8
Sambandam, N.9
Muslin, A.J.10
-
42
-
-
84885455062
-
The eIF2alpha/ATF4 pathway is essential for stress-induced autophagy gene expression
-
PID: 23804767
-
B’Chir W, Maurin AC, Carraro V, Averous J, Jousse C, Muranishi Y, Parry L, Stepien G, Fafournoux P, Bruhat A (2013) The eIF2alpha/ATF4 pathway is essential for stress-induced autophagy gene expression. Nucleic Acids Res 41(16):7683–7699. doi:10.1093/nar/gkt563
-
(2013)
Nucleic Acids Res
, vol.41
, Issue.16
, pp. 7683-7699
-
-
B’Chir, W.1
Maurin, A.C.2
Carraro, V.3
Averous, J.4
Jousse, C.5
Muranishi, Y.6
Parry, L.7
Stepien, G.8
Fafournoux, P.9
Bruhat, A.10
-
43
-
-
74949118681
-
The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5
-
COI: 1:CAS:528:DC%2BC3cXislWntQ%3D%3D, PID: 20038797
-
Rouschop KMA, van den Beucken T, Dubois L, Niessen H, Bussink J, Savelkouls K, Keulers T, Mujcic H, Landuyt W, Voncken JW, Lambin P, van der Kogel AJ, Koritzinsky M, Wouters BG (2010) The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5. J Clin Invest 120(1):127–141. doi:10.1172/Jci40027
-
(2010)
J Clin Invest
, vol.120
, Issue.1
, pp. 127-141
-
-
Rouschop, K.M.A.1
van den Beucken, T.2
Dubois, L.3
Niessen, H.4
Bussink, J.5
Savelkouls, K.6
Keulers, T.7
Mujcic, H.8
Landuyt, W.9
Voncken, J.W.10
Lambin, P.11
van der Kogel, A.J.12
Koritzinsky, M.13
Wouters, B.G.14
-
44
-
-
84890833205
-
BECN1/Beclin 1 is recruited into lipid rafts by prion to activate autophagy in response to amyloid beta 42
-
COI: 1:CAS:528:DC%2BC2cXhtFyrtbfE, PID: 24145555
-
Nah J, Pyo JO, Jung S, Yoo SM, Kam TI, Chang J, Han J, Soo AAS, Onodera T, Jung YK (2013) BECN1/Beclin 1 is recruited into lipid rafts by prion to activate autophagy in response to amyloid beta 42. Autophagy 9(12):2009–2021
-
(2013)
Autophagy
, vol.9
, Issue.12
, pp. 2009-2021
-
-
Nah, J.1
Pyo, J.O.2
Jung, S.3
Yoo, S.M.4
Kam, T.I.5
Chang, J.6
Han, J.7
Soo, A.A.S.8
Onodera, T.9
Jung, Y.K.10
-
45
-
-
0037174618
-
Alzheimer’s disease is a synaptic failure
-
COI: 1:CAS:528:DC%2BD38XotFSnur0%3D
-
Selkoe DJ (2002) Alzheimer’s disease is a synaptic failure. Sci 298(5594):789–791. doi:10.1126/science.1074069
-
(2002)
Sci
, vol.298
, Issue.5594
, pp. 789-791
-
-
Selkoe, D.J.1
-
46
-
-
0029561823
-
Aplysia CREB2 represses long-term facilitation: relief of repression converts transient facilitation into long-term functional and structural change
-
COI: 1:CAS:528:DyaK2MXhtVSnu7bF, PID: 8521521
-
Bartsch D, Ghirardi M, Skehel PA, Karl KA, Herder SP, Chen M, Bailey CH, Kandel ER (1995) Aplysia CREB2 represses long-term facilitation: relief of repression converts transient facilitation into long-term functional and structural change. Cell 83(6):979–992
-
(1995)
Cell
, vol.83
, Issue.6
, pp. 979-992
-
-
Bartsch, D.1
Ghirardi, M.2
Skehel, P.A.3
Karl, K.A.4
Herder, S.P.5
Chen, M.6
Bailey, C.H.7
Kandel, E.R.8
-
47
-
-
77249127919
-
eIF2alpha Phosphorylation-dependent translation in CA1 pyramidal cells impairs hippocampal memory consolidation without affecting general translation
-
COI: 1:CAS:528:DC%2BC3cXisVKltrY%3D, PID: 20164343
-
Jiang Z, Belforte JE, Lu Y, Yabe Y, Pickel J, Smith CB, Je HS, Lu B, Nakazawa K (2010) eIF2alpha Phosphorylation-dependent translation in CA1 pyramidal cells impairs hippocampal memory consolidation without affecting general translation. J Neurosci 30(7):2582–2594. doi:10.1523/JNEUROSCI. 3971-09.2010
-
(2010)
J Neurosci
, vol.30
, Issue.7
, pp. 2582-2594
-
-
Jiang, Z.1
Belforte, J.E.2
Lu, Y.3
Yabe, Y.4
Pickel, J.5
Smith, C.B.6
Je, H.S.7
Lu, B.8
Nakazawa, K.9
-
48
-
-
7244260495
-
Alzheimer’s disease meets the ubiquitin-proteasome system
-
COI: 1:CAS:528:DC%2BD2cXptFKktbc%3D, PID: 15519283
-
Song S, Jung YK (2004) Alzheimer’s disease meets the ubiquitin-proteasome system. Trends Mol Med 10(11):565–570. doi:10.1016/j.molmed.2004.09.005
-
(2004)
Trends Mol Med
, vol.10
, Issue.11
, pp. 565-570
-
-
Song, S.1
Jung, Y.K.2
-
49
-
-
43049090872
-
Proteasome inhibition enhances the induction and impairs the maintenance of late-phase long-term potentiation
-
COI: 1:CAS:528:DC%2BD1cXotFGns7s%3D, PID: 18441292
-
Dong C, Upadhya SC, Ding L, Smith TK, Hegde AN (2008) Proteasome inhibition enhances the induction and impairs the maintenance of late-phase long-term potentiation. Learn Mem 15(5):335–347. doi:10.1101/lm.984508
-
(2008)
Learn Mem
, vol.15
, Issue.5
, pp. 335-347
-
-
Dong, C.1
Upadhya, S.C.2
Ding, L.3
Smith, T.K.4
Hegde, A.N.5
-
50
-
-
84903707352
-
Activating transcription factor 4 (ATF4) modulates post-synaptic development and dendritic spine morphology
-
Liu J, Pasini S, Shelanski ML, Greene LA (2014) Activating transcription factor 4 (ATF4) modulates post-synaptic development and dendritic spine morphology. Front Cell Neurosci 8
-
(2014)
Front Cell Neurosci
, pp. 8
-
-
Liu, J.1
Pasini, S.2
Shelanski, M.L.3
Greene, L.A.4
-
51
-
-
84879128268
-
Modulation of 5-lipoxygenase in proteotoxicity and Alzheimer’s disease
-
COI: 1:CAS:528:DC%2BC3sXhtVWmtr%2FO, PID: 23785163
-
Valera E, Dargusch R, Maher PA, Schubert D (2013) Modulation of 5-lipoxygenase in proteotoxicity and Alzheimer’s disease. J Neurosci 33(25):10512–10525. doi:10.1523/Jneurosci.5183-12.2013
-
(2013)
J Neurosci
, vol.33
, Issue.25
, pp. 10512-10525
-
-
Valera, E.1
Dargusch, R.2
Maher, P.A.3
Schubert, D.4
|