Calreticulin levels determine onset of early muscle denervation by fast motoneurons of ALS model mice

Neurobiology of Disease

Volumn 73, Issue , 2015, Pages 130-136

  Bernard Marissal, Nathalie ^a,b   Sunyach, Claire ^a   Marissal, Thomas ^c   Raoul, Cédric ^a,d   Pettmann, Brigitte ^a  

^a Turing Center for Living Systems CENTURI Aix Marseille University   (France)

^b UNIVERSITY OF LAUSANNE   (Switzerland)

^c UNIVERSITY OF GENEVA   (Switzerland)

^d HÔPITAL SAINT ELOI   (France)

Author keywords

ALS; Calreticulin; ER stress; MTOR; Muscle weakness and denervation

Indexed keywords

CALRETICULIN; MAMMALIAN TARGET OF RAPAMYCIN; ACTIVATING TRANSCRIPTION FACTOR 6; ATF6 PROTEIN, MOUSE; CHOLINERGIC RECEPTOR; INITIATION FACTOR 2; MTOR PROTEIN, MOUSE; SLC18A3 PROTEIN, MOUSE; SOD1 G93A PROTEIN; SUPEROXIDE DISMUTASE; TARGET OF RAPAMYCIN KINASE; VESICULAR ACETYLCHOLINE TRANSPORTER;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; FAST MUSCLE FIBER; FEMALE; MALE; MOTONEURON; MOUSE; MUSCLE DENERVATION; MUSCLE WEAKNESS; NERVE CELL DEGENERATION; NERVE CELL NECROSIS; NONHUMAN; PROTEIN EXPRESSION; UNFOLDED PROTEIN RESPONSE; UPREGULATION; AGE; ANIMAL; COMPLICATION; DISEASE MODEL; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MUSCULAR DISEASES; NERVE DEGENERATION; PATHOLOGY; SPINAL CORD; TRANSGENIC MOUSE;

ACTIVATING TRANSCRIPTION FACTOR 6; AGE FACTORS; AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; CALRETICULIN; DISEASE MODELS, ANIMAL; EUKARYOTIC INITIATION FACTOR-2; GENE EXPRESSION REGULATION; MICE; MICE, TRANSGENIC; MOTOR NEURONS; MUSCLE WEAKNESS; MUSCULAR DISEASES; NERVE DEGENERATION; RECEPTORS, CHOLINERGIC; SPINAL CORD; SUPEROXIDE DISMUTASE; TOR SERINE-THREONINE KINASES; VESICULAR ACETYLCHOLINE TRANSPORT PROTEINS;

EID: 84908544396     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2014.09.009     Document Type: Article

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