-
1
-
-
67149107430
-
HIF-1 modulates dietary restriction-mediated lifespan extension via IRE-1 in Caenorhabditis elegans
-
Chen D, Thomas EL, Kapahi P (2009) HIF-1 modulates dietary restriction-mediated lifespan extension via IRE-1 in Caenorhabditis elegans. PLoS Genet. 5, e1000486.
-
(2009)
PLoS Genet.
, vol.5
-
-
Chen, D.1
Thomas, E.L.2
Kapahi, P.3
-
2
-
-
26444524411
-
Cholesterol-induced macrophage apoptosis requires ER stress pathways and engagement of the type A scavenger receptor
-
Devries-Seimon T, Li Y, Yao PM, Stone E, Wang Y, Davis RJ, Flavell R, Tabas I (2005) Cholesterol-induced macrophage apoptosis requires ER stress pathways and engagement of the type A scavenger receptor. J. Cell Biol. 171, 61-73.
-
(2005)
J. Cell Biol.
, vol.171
, pp. 61-73
-
-
Devries-Seimon, T.1
Li, Y.2
Yao, P.M.3
Stone, E.4
Wang, Y.5
Davis, R.J.6
Flavell, R.7
Tabas, I.8
-
3
-
-
34447272054
-
Eca1, a sarcoplasmic/endoplasmic reticulum Ca2 + -ATPase, is involved in stress tolerance and virulence in Cryptococcus neoformans
-
Fan W, Idnurm A, Breger J, Mylonakis E, Heitman J (2007) Eca1, a sarcoplasmic/endoplasmic reticulum Ca2 + -ATPase, is involved in stress tolerance and virulence in Cryptococcus neoformans. Infect. Immun. 75, 3394-3405.
-
(2007)
Infect. Immun.
, vol.75
, pp. 3394-3405
-
-
Fan, W.1
Idnurm, A.2
Breger, J.3
Mylonakis, E.4
Heitman, J.5
-
4
-
-
84878441683
-
Neuroprotection of interleukin-6 against NMDA-induced neurotoxicity is mediated by JAK/STAT3, MAPK/ERK, and PI3K/AKT signaling pathways
-
Fang XX, Jiang XL, Han XH, Peng YP, Qiu YH (2013) Neuroprotection of interleukin-6 against NMDA-induced neurotoxicity is mediated by JAK/STAT3, MAPK/ERK, and PI3K/AKT signaling pathways. Cell. Mol. Neurobiol. 33, 241-251.
-
(2013)
Cell. Mol. Neurobiol.
, vol.33
, pp. 241-251
-
-
Fang, X.X.1
Jiang, X.L.2
Han, X.H.3
Peng, Y.P.4
Qiu, Y.H.5
-
5
-
-
68049110633
-
IRE1alpha kinase activation modes control alternate endoribonuclease outputs to determine divergent cell fates
-
Han D, Lerner AG, Vande Walle L, Upton JP, Xu W, Hagen A, Backes BJ, Oakes SA, Papa FR (2009) IRE1alpha kinase activation modes control alternate endoribonuclease outputs to determine divergent cell fates. Cell 138, 562-575.
-
(2009)
Cell
, vol.138
, pp. 562-575
-
-
Han, D.1
Lerner, A.G.2
Vande Walle, L.3
Upton, J.P.4
Xu, W.5
Hagen, A.6
Backes, B.J.7
Oakes, S.A.8
Papa, F.R.9
-
6
-
-
77953091249
-
Insulin/IGF-1 signaling mutants reprogram ER stress response regulators to promote longevity
-
Henis-Korenblit S, Zhang P, Hansen M, McCormick M, Lee SJ, Cary M, Kenyon C (2010) Insulin/IGF-1 signaling mutants reprogram ER stress response regulators to promote longevity. Proc. Natl Acad. Sci. USA 107, 9730-9735.
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 9730-9735
-
-
Henis-Korenblit, S.1
Zhang, P.2
Hansen, M.3
McCormick, M.4
Lee, S.J.5
Cary, M.6
Kenyon, C.7
-
7
-
-
33745893809
-
Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response
-
Hollien J, Weissman JS (2006) Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response. Science 313, 104-107.
-
(2006)
Science
, vol.313
, pp. 104-107
-
-
Hollien, J.1
Weissman, J.S.2
-
8
-
-
68549092781
-
Regulated Ire1-dependent decay of messenger RNAs in mammalian cells
-
Hollien J, Lin JH, Li H, Stevens N, Walter P, Weissman JS (2009) Regulated Ire1-dependent decay of messenger RNAs in mammalian cells. J. Cell Biol. 186, 323-331.
-
(2009)
J. Cell Biol.
, vol.186
, pp. 323-331
-
-
Hollien, J.1
Lin, J.H.2
Li, H.3
Stevens, N.4
Walter, P.5
Weissman, J.S.6
-
9
-
-
84858704659
-
Selective autophagy in the maintenance of cellular homeostasis in aging organisms
-
Hubbard VM, Valdor R, Fernando M, Cuervo AM (2012) Selective autophagy in the maintenance of cellular homeostasis in aging organisms. Biogerontology 13, 21-35.
-
(2012)
Biogerontology
, vol.13
, pp. 21-35
-
-
Hubbard, V.M.1
Valdor, R.2
Fernando, M.3
Cuervo, A.M.4
-
10
-
-
84856856011
-
IRE1alpha activation protects mice against acetaminophen-induced hepatotoxicity
-
Hur KY, So JS, Ruda V, Frank-Kamenetsky M, Fitzgerald K, Koteliansky V, Iwawaki T, Glimcher LH, Lee AH (2012) IRE1alpha activation protects mice against acetaminophen-induced hepatotoxicity. J. Exp. Med. 209, 307-318.
-
(2012)
J. Exp. Med.
, vol.209
, pp. 307-318
-
-
Hur, K.Y.1
So, J.S.2
Ruda, V.3
Frank-Kamenetsky, M.4
Fitzgerald, K.5
Koteliansky, V.6
Iwawaki, T.7
Glimcher, L.H.8
Lee, A.H.9
-
11
-
-
33847149663
-
Reduced eIF2alpha phosphorylation and increased proapoptotic proteins in aging
-
Hussain SG, Ramaiah KV (2007) Reduced eIF2alpha phosphorylation and increased proapoptotic proteins in aging. Biochem. Biophys. Res. Commun. 355, 365-370.
-
(2007)
Biochem. Biophys. Res. Commun.
, vol.355
, pp. 365-370
-
-
Hussain, S.G.1
Ramaiah, K.V.2
-
12
-
-
61449181271
-
HCV induces oxidative and ER stress, and sensitizes infected cells to apoptosis in SCID/Alb-uPA mice
-
Joyce MA, Walters KA, Lamb SE, Yeh MM, Zhu LF, Kneteman N, Doyle JS, Katze MG, Tyrrell DL (2009) HCV induces oxidative and ER stress, and sensitizes infected cells to apoptosis in SCID/Alb-uPA mice. PLoS Pathog. 5, e1000291.
-
(2009)
PLoS Pathog.
, vol.5
-
-
Joyce, M.A.1
Walters, K.A.2
Lamb, S.E.3
Yeh, M.M.4
Zhu, L.F.5
Kneteman, N.6
Doyle, J.S.7
Katze, M.G.8
Tyrrell, D.L.9
-
13
-
-
2342627368
-
Elevated gadd153/chop expression and enhanced c-Jun N-terminal protein kinase activation sensitizes aged cells to ER stress
-
Li J, Holbrook NJ (2004) Elevated gadd153/chop expression and enhanced c-Jun N-terminal protein kinase activation sensitizes aged cells to ER stress. Exp. Gerontol. 39, 735-744.
-
(2004)
Exp. Gerontol.
, vol.39
, pp. 735-744
-
-
Li, J.1
Holbrook, N.J.2
-
14
-
-
77957772337
-
Differences in endoplasmic reticulum stress signalling kinetics determine cell survival outcome through activation of MKP-1
-
Li B, Yi P, Zhang B, Xu C, Liu Q, Pi Z, Xu X, Chevet E, Liu J (2011) Differences in endoplasmic reticulum stress signalling kinetics determine cell survival outcome through activation of MKP-1. Cell. Signal. 23, 35-45.
-
(2011)
Cell. Signal.
, vol.23
, pp. 35-45
-
-
Li, B.1
Yi, P.2
Zhang, B.3
Xu, C.4
Liu, Q.5
Pi, Z.6
Xu, X.7
Chevet, E.8
Liu, J.9
-
15
-
-
0034022635
-
Impairment with various antioxidants of the loss of mitochondrial transmembrane potential and of the cytosolic release of cytochrome c occuring during 7-ketocholesterol-induced apoptosis
-
Lizard G, Miguet C, Bessede G, Monier S, Gueldry S, Neel D, Gambert P (2000) Impairment with various antioxidants of the loss of mitochondrial transmembrane potential and of the cytosolic release of cytochrome c occuring during 7-ketocholesterol-induced apoptosis. Free Radic. Biol. Med. 28, 743-753.
-
(2000)
Free Radic. Biol. Med.
, vol.28
, pp. 743-753
-
-
Lizard, G.1
Miguet, C.2
Bessede, G.3
Monier, S.4
Gueldry, S.5
Neel, D.6
Gambert, P.7
-
16
-
-
67349217063
-
ER and aging-Protein folding and the ER stress response
-
Naidoo N (2009) ER and aging-Protein folding and the ER stress response. Ageing Res. Rev. 8, 150-159.
-
(2009)
Ageing Res. Rev.
, vol.8
, pp. 150-159
-
-
Naidoo, N.1
-
17
-
-
33750935613
-
Functionality of unspliced XBP1 is required to explain evolution of overlapping reading frames
-
Nekrutenko A, He J (2006) Functionality of unspliced XBP1 is required to explain evolution of overlapping reading frames. Trends Genet. 22, 645-648.
-
(2006)
Trends Genet.
, vol.22
, pp. 645-648
-
-
Nekrutenko, A.1
He, J.2
-
18
-
-
0036320896
-
Phagocytosis of apoptotic cells by macrophages from NOD mice is reduced
-
O'Brien BA, Huang Y, Geng X, Dutz JP, Finegood DT (2002) Phagocytosis of apoptotic cells by macrophages from NOD mice is reduced. Diabetes 51, 2481-2488.
-
(2002)
Diabetes
, vol.51
, pp. 2481-2488
-
-
O'Brien, B.A.1
Huang, Y.2
Geng, X.3
Dutz, J.P.4
Finegood, D.T.5
-
19
-
-
1842843855
-
Roles of CHOP/GADD153 in endoplasmic reticulum stress
-
Oyadomari S, Mori M (2004) Roles of CHOP/GADD153 in endoplasmic reticulum stress. Cell Death Differ. 11, 381-389.
-
(2004)
Cell Death Differ.
, vol.11
, pp. 381-389
-
-
Oyadomari, S.1
Mori, M.2
-
20
-
-
33646512882
-
Cellular environment facilitates protein accumulation in aged rat hippocampus
-
Paz Gavilan M, Vela J, Castano A, Ramos B, del Rio JC, Vitorica J, Ruano D (2006) Cellular environment facilitates protein accumulation in aged rat hippocampus. Neurobiol. Aging 27, 973-982.
-
(2006)
Neurobiol. Aging
, vol.27
, pp. 973-982
-
-
Paz Gavilan, M.1
Vela, J.2
Castano, A.3
Ramos, B.4
del Rio, J.C.5
Vitorica, J.6
Ruano, D.7
-
21
-
-
33746596554
-
Construction and characterization of an attenuated purine auxotroph in a Francisella tularensis live vaccine strain
-
Pechous R, Celli J, Penoske R, Hayes SF, Frank DW, Zahrt TC (2006) Construction and characterization of an attenuated purine auxotroph in a Francisella tularensis live vaccine strain. Infect. Immun. 74, 4452-4461.
-
(2006)
Infect. Immun.
, vol.74
, pp. 4452-4461
-
-
Pechous, R.1
Celli, J.2
Penoske, R.3
Hayes, S.F.4
Frank, D.W.5
Zahrt, T.C.6
-
22
-
-
10044220931
-
NAD(P)H oxidase Nox-4 mediates 7-ketocholesterol-induced endoplasmic reticulum stress and apoptosis in human aortic smooth muscle cells
-
Pedruzzi E, Guichard C, Ollivier V, Driss F, Fay M, Prunet C, Marie JC, Pouzet C, Samadi M, Elbim C, O'Dowd Y, Bens M, Vandewalle A, Gougerot-Pocidalo MA, Lizard G, Ogier-Denis E (2004) NAD(P)H oxidase Nox-4 mediates 7-ketocholesterol-induced endoplasmic reticulum stress and apoptosis in human aortic smooth muscle cells. Mol. Cell. Biol. 24, 10703-10717.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 10703-10717
-
-
Pedruzzi, E.1
Guichard, C.2
Ollivier, V.3
Driss, F.4
Fay, M.5
Prunet, C.6
Marie, J.C.7
Pouzet, C.8
Samadi, M.9
Elbim, C.10
O'Dowd, Y.11
Bens, M.12
Vandewalle, A.13
Gougerot-Pocidalo, M.A.14
Lizard, G.15
Ogier-Denis, E.16
-
23
-
-
79952842932
-
The critical role of GRP78 in physiologic and pathologic stress
-
Pfaffenbach KT, Lee AS (2011) The critical role of GRP78 in physiologic and pathologic stress. Curr. Opin. Cell Bio. 23, 150-156.
-
(2011)
Curr. Opin. Cell Bio.
, vol.23
, pp. 150-156
-
-
Pfaffenbach, K.T.1
Lee, A.S.2
-
24
-
-
34250899722
-
Signal integration in the endoplasmic reticulum unfolded protein response
-
Ron D, Walter P (2007) Signal integration in the endoplasmic reticulum unfolded protein response. Nat. Rev. 8, 519-529.
-
(2007)
Nat. Rev.
, vol.8
, pp. 519-529
-
-
Ron, D.1
Walter, P.2
-
25
-
-
77952552782
-
ER stress and hormetic regulation of the aging process
-
Salminen A, Kaarniranta K (2010) ER stress and hormetic regulation of the aging process. Ageing Res. Rev. 9, 211-217.
-
(2010)
Ageing Res. Rev.
, vol.9
, pp. 211-217
-
-
Salminen, A.1
Kaarniranta, K.2
-
26
-
-
77958577703
-
Induction of ER stress in macrophages of tuberculosis granulomas
-
Seimon TA, Kim MJ, Blumenthal A, Koo J, Ehrt S, Wainwright H, Bekker LG, Kaplan G, Nathan C, Tabas I, Russell DG (2010a) Induction of ER stress in macrophages of tuberculosis granulomas. PLoS ONE 5, e12772.
-
(2010)
PLoS ONE
, vol.5
-
-
Seimon, T.A.1
Kim, M.J.2
Blumenthal, A.3
Koo, J.4
Ehrt, S.5
Wainwright, H.6
Bekker, L.G.7
Kaplan, G.8
Nathan, C.9
Tabas, I.10
Russell, D.G.11
-
27
-
-
77958532945
-
Atherogenic lipids and lipoproteins trigger CD36-TLR2-dependent apoptosis in macrophages undergoing endoplasmic reticulum stress
-
Seimon TA, Nadolski MJ, Liao XH, Magallon J, Nguyen M, Feric NT, Koschinsky ML, Harkewicz R, Witztum JL, Tsimikas S, Golenbock D, Moore KJ, Tabas I (2010b) Atherogenic lipids and lipoproteins trigger CD36-TLR2-dependent apoptosis in macrophages undergoing endoplasmic reticulum stress. Cell Metab. 12, 467-482.
-
(2010)
Cell Metab.
, vol.12
, pp. 467-482
-
-
Seimon, T.A.1
Nadolski, M.J.2
Liao, X.H.3
Magallon, J.4
Nguyen, M.5
Feric, N.T.6
Koschinsky, M.L.7
Harkewicz, R.8
Witztum, J.L.9
Tsimikas, S.10
Golenbock, D.11
Moore, K.J.12
Tabas, I.13
-
28
-
-
70349479191
-
Calcium and cell death signaling in neurodegeneration and aging
-
Smaili S, Hirata H, Ureshino R, Monteforte PT, Morales AP, Muler ML, Terashima J, Oseki K, Rosenstock TR, Lopes GS, Bincoletto C (2009) Calcium and cell death signaling in neurodegeneration and aging. An. Acad. Bras. Cienc. 81, 467-475.
-
(2009)
An. Acad. Bras. Cienc.
, vol.81
, pp. 467-475
-
-
Smaili, S.1
Hirata, H.2
Ureshino, R.3
Monteforte, P.T.4
Morales, A.P.5
Muler, M.L.6
Terashima, J.7
Oseki, K.8
Rosenstock, T.R.9
Lopes, G.S.10
Bincoletto, C.11
-
29
-
-
74149084149
-
Marginal zinc deficiency increases oxidative DNA damage in the prostate after chronic exercise
-
Song Y, Elias V, Loban A, Scrimgeour AG, Ho E (2010) Marginal zinc deficiency increases oxidative DNA damage in the prostate after chronic exercise. Free Radic. Biol. Med. 48, 82-88.
-
(2010)
Free Radic. Biol. Med.
, vol.48
, pp. 82-88
-
-
Song, Y.1
Elias, V.2
Loban, A.3
Scrimgeour, A.G.4
Ho, E.5
-
30
-
-
27644537437
-
Consequences and therapeutic implications of macrophage apoptosis in atherosclerosis: the importance of lesion stage and phagocytic efficiency
-
Tabas I (2005) Consequences and therapeutic implications of macrophage apoptosis in atherosclerosis: the importance of lesion stage and phagocytic efficiency. Arterioscler. Thromb. Vasc. Biol. 25, 2255-2264.
-
(2005)
Arterioscler. Thromb. Vasc. Biol.
, vol.25
, pp. 2255-2264
-
-
Tabas, I.1
-
31
-
-
77958003056
-
The role of endoplasmic reticulum stress in the progression of atherosclerosis
-
Tabas I (2010) The role of endoplasmic reticulum stress in the progression of atherosclerosis. Circ. Res. 107, 839-850.
-
(2010)
Circ. Res.
, vol.107
, pp. 839-850
-
-
Tabas, I.1
-
32
-
-
79952264011
-
Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress
-
Tabas I, Ron D (2011) Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress. Nat. Cell Biol. 13, 184-190.
-
(2011)
Nat. Cell Biol.
, vol.13
, pp. 184-190
-
-
Tabas, I.1
Ron, D.2
-
33
-
-
70349696241
-
Calcium/calmodulin-dependent protein kinase II links ER stress with Fas and mitochondrial apoptosis pathways
-
Timmins JM, Ozcan L, Seimon TA, Li G, Malagelada C, Backs J, Backs T, Bassel-Duby R, Olson EN, Anderson ME, Tabas I (2009) Calcium/calmodulin-dependent protein kinase II links ER stress with Fas and mitochondrial apoptosis pathways. J. Clin. Invest. 119, 2925-2941.
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 2925-2941
-
-
Timmins, J.M.1
Ozcan, L.2
Seimon, T.A.3
Li, G.4
Malagelada, C.5
Backs, J.6
Backs, T.7
Bassel-Duby, R.8
Olson, E.N.9
Anderson, M.E.10
Tabas, I.11
-
34
-
-
0028880006
-
Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis
-
Xia Z, Dickens M, Raingeaud J, Davis RJ, Greenberg ME (1995) Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science 270, 1326-1331.
-
(1995)
Science
, vol.270
, pp. 1326-1331
-
-
Xia, Z.1
Dickens, M.2
Raingeaud, J.3
Davis, R.J.4
Greenberg, M.E.5
-
35
-
-
0034604701
-
Free cholesterol loading of macrophages induces apoptosis involving the fas pathway
-
Yao PM, Tabas I (2000) Free cholesterol loading of macrophages induces apoptosis involving the fas pathway. J. Bio. Chem. 275, 23807-23813.
-
(2000)
J. Bio. Chem.
, vol.275
, pp. 23807-23813
-
-
Yao, P.M.1
Tabas, I.2
-
36
-
-
0035966269
-
XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor
-
Yoshida H, Matsui T, Yamamoto A, Okada T, Mori K (2001) XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor. Cell 107, 881-891.
-
(2001)
Cell
, vol.107
, pp. 881-891
-
-
Yoshida, H.1
Matsui, T.2
Yamamoto, A.3
Okada, T.4
Mori, K.5
-
37
-
-
0042691414
-
Unfolding the toxicity of cholesterol
-
Zhang K, Kaufman RJ (2003) Unfolding the toxicity of cholesterol. Nat. Cell Biol. 5, 769-770.
-
(2003)
Nat. Cell Biol.
, vol.5
, pp. 769-770
-
-
Zhang, K.1
Kaufman, R.J.2
-
38
-
-
58849167699
-
The isolation and characterization of murine macrophages
-
Chapter 14, Unit 14.1.
-
Zhang X, Goncalves R, Mosser DM (2008) The isolation and characterization of murine macrophages. Curr. Protoc. Immunol. Chapter 14, Unit 14.1.
-
(2008)
Curr. Protoc. Immunol.
-
-
Zhang, X.1
Goncalves, R.2
Mosser, D.M.3
|