-
1
-
-
0033850407
-
Tau protein isoforms, phosphorylation and role in neurodegenerative disorders
-
Buée L, Bussière T, Buée-Scherrer V, Delacourte A, Hof PR (2000) Tau protein isoforms, phosphorylation and role in neurodegenerative disorders. Brain Res Brain Res Rev 33: 95-130.
-
(2000)
Brain Res Brain Res Rev
, vol.33
, pp. 95-130
-
-
Buée, L.1
Bussière, T.2
Buée-Scherrer, V.3
Delacourte, A.4
Hof, P.R.5
-
2
-
-
0026740795
-
Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease
-
Arriagada PV, Growdon JH, Hedley-White ET, Hyman BT (1992) Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease. Neurology 42: 631-639.
-
(1992)
Neurology
, vol.42
, pp. 631-639
-
-
Arriagada, P.V.1
Growdon, J.H.2
Hedley-White, E.T.3
Hyman, B.T.4
-
3
-
-
0032543684
-
Association of missense and 59-splice-site mutations in tau with the inherited dementia FTDP-17
-
Hutton M, Lendon CL, Rizzu P, Baker M, Froelich S, et al. (1998) Association of missense and 59-splice-site mutations in tau with the inherited dementia FTDP-17. Nature 393: 702-705.
-
(1998)
Nature
, vol.393
, pp. 702-705
-
-
Hutton, M.1
Lendon, C.L.2
Rizzu, P.3
Baker, M.4
Froelich, S.5
-
4
-
-
14444284106
-
Tau is a candidate gene for chromosome 17 frontotemporal dementia
-
Poorkaj P, Bird TD, Wijsman E, Nemens E, Garruto RM, et al. (1998) Tau is a candidate gene for chromosome 17 frontotemporal dementia. Ann Neurol 43: 815-825.
-
(1998)
Ann Neurol
, vol.43
, pp. 815-825
-
-
Poorkaj, P.1
Bird, T.D.2
Wijsman, E.3
Nemens, E.4
Garruto, R.M.5
-
5
-
-
0032560487
-
Mutation in the tau gene in familial multiple system tauopathy with presenile dementia
-
Spillantini MMG, Murrell JR, Goedert M, Farlow MR, Klug A, et al. (1998) Mutation in the tau gene in familial multiple system tauopathy with presenile dementia. Proc Natl Acad Sci U S A 95: 7737-7741.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 7737-7741
-
-
Spillantini, M.M.G.1
Murrell, J.R.2
Goedert, M.3
Farlow, M.R.4
Klug, A.5
-
6
-
-
24344489466
-
The unfolded protein response is activated in Alzheimer's disease
-
Hoozemans JJ, Veerhuis R, Van Haastert ES, Rozemuller JM, Baas F, Eikelenboom P, Scheper W (2005) The unfolded protein response is activated in Alzheimer's disease. Acta Neuropathol 110: 165-172.
-
(2005)
Acta Neuropathol
, vol.110
, pp. 165-172
-
-
Hoozemans, J.J.1
Veerhuis, R.2
Van Haastert, E.S.3
Rozemuller, J.M.4
Baas, F.5
Eikelenboom, P.6
Scheper, W.7
-
7
-
-
33744985455
-
Endoplasmic reticulum stress features are prominent in Alzheimer disease but not in prion diseases in vivo
-
Unterberger U, Höftberger R, Gelpi E, Flicker H, Budka H, Voigtländer T (2006) Endoplasmic reticulum stress features are prominent in Alzheimer disease but not in prion diseases in vivo. J Neuropathol Exp Neurol 65: 348-357.
-
(2006)
J Neuropathol Exp Neurol
, vol.65
, pp. 348-357
-
-
Unterberger, U.1
Höftberger, R.2
Gelpi, E.3
Flicker, H.4
Budka, H.5
Voigtländer, T.6
-
8
-
-
22244446505
-
The mammalian unfolded protein response
-
Schröder M, Kaufman RJ (2005) The mammalian unfolded protein response. Annu Rev Biochem 74: 739-789.
-
(2005)
Annu Rev Biochem
, vol.74
, pp. 739-789
-
-
Schröder, M.1
Kaufman, R.J.2
-
9
-
-
41749108854
-
Endoplasmic reticulum stress in disease pathogenesis
-
Lin JH, Walter P, Yen TS (2008) Endoplasmic reticulum stress in disease pathogenesis. Annu Rev Pathol 3: 399-425.
-
(2008)
Annu Rev Pathol
, vol.3
, pp. 399-425
-
-
Lin, J.H.1
Walter, P.2
Yen, T.S.3
-
10
-
-
35848951621
-
Abeta 1-42 induces mild endoplasmic reticulum stress in an aggregation state-dependent manner
-
Chafekar SM, Hoozemans JJ, Zwart R, Baas F, Scheper W (2007) Abeta 1-42 induces mild endoplasmic reticulum stress in an aggregation state-dependent manner. Antioxid Redox Signal 9: 2245-2254.
-
(2007)
Antioxid Redox Signal
, vol.9
, pp. 2245-2254
-
-
Chafekar, S.M.1
Hoozemans, J.J.2
Zwart, R.3
Baas, F.4
Scheper, W.5
-
11
-
-
53649085618
-
Increased Abeta1-42 production sensitizes neuroblastoma cells for ER stress toxicity
-
Chafekar SM, Zwart R, Veerhuis R, Vanderstichele H, Baas F, Scheper W (2008) Increased Abeta1-42 production sensitizes neuroblastoma cells for ER stress toxicity. Curr Alzheimer Res 5: 469-474.
-
(2008)
Curr Alzheimer Res
, vol.5
, pp. 469-474
-
-
Chafekar, S.M.1
Zwart, R.2
Veerhuis, R.3
Vanderstichele, H.4
Baas, F.5
Scheper, W.6
-
12
-
-
65349093893
-
The unfolded protein response is activated in pretangle neurons in Alzheimer's disease hippocampus
-
Hoozemans JJ, van Haastert ES, Nijholt DA, Rozemuller AJ, Eikelenboom P, Scheper W (2009) The unfolded protein response is activated in pretangle neurons in Alzheimer's disease hippocampus. Am J Pathol 174: 1241-1251.
-
(2009)
Am J Pathol
, vol.174
, pp. 1241-1251
-
-
Hoozemans, J.J.1
van Haastert, E.S.2
Nijholt, D.A.3
Rozemuller, A.J.4
Eikelenboom, P.5
Scheper, W.6
-
13
-
-
0035958642
-
Tauopathy in Drosophila: Neurodegeneration without neurofibrillary tangles
-
Wittmann CW, Wszolek MF, Shulman JM, Salvaterra PM, Lewis J, et al. (2001) Tauopathy in Drosophila: neurodegeneration without neurofibrillary tangles. Science 293: 711-714.
-
(2001)
Science
, vol.293
, pp. 711-714
-
-
Wittmann, C.W.1
Wszolek, M.F.2
Shulman, J.M.3
Salvaterra, P.M.4
Lewis, J.5
-
14
-
-
0037118247
-
Human wild-type tau interacts with wingless pathway components and produces neurofibrillary pathology in Drosophila
-
Jackson GR, Wiedau-Pazos M, Sang TK, Wagle N, Brown CA, et al. (2002) Human wild-type tau interacts with wingless pathway components and produces neurofibrillary pathology in Drosophila. Neuron 34: 509-519.
-
(2002)
Neuron
, vol.34
, pp. 509-519
-
-
Jackson, G.R.1
Wiedau-Pazos, M.2
Sang, T.K.3
Wagle, N.4
Brown, C.A.5
-
15
-
-
1542358895
-
PAR-1 kinase plays an initiator role in a temporally ordered phosphorylation process that confers tau toxicity in Drosophila
-
Nishimura I, Yang Y, Lu B (2004) PAR-1 kinase plays an initiator role in a temporally ordered phosphorylation process that confers tau toxicity in Drosophila. Cell 116: 671-682.
-
(2004)
Cell
, vol.116
, pp. 671-682
-
-
Nishimura, I.1
Yang, Y.2
Lu, B.3
-
16
-
-
34248219026
-
S/P and T/P phosphorylation is critical for tau neurotoxicity in Drosophila
-
Steinhilb ML, Dias-Santagata D, Mulkearns EE, Shulman JM, Biernat J, Mandelkow EM, Feany MB (2007) S/P and T/P phosphorylation is critical for tau neurotoxicity in Drosophila. J Neurosci Res 85: 1271-1278.
-
(2007)
J Neurosci Res
, vol.85
, pp. 1271-1278
-
-
Steinhilb, M.L.1
Dias-Santagata, D.2
Mulkearns, E.E.3
Shulman, J.M.4
Biernat, J.5
Mandelkow, E.M.6
Feany, M.B.7
-
17
-
-
37049027122
-
Tau phosphorylation sites work in concert to promote neurotoxicity in vivo
-
Steinhilb ML, Dias-Santagata D, Fulga TA, Felch DL, Feany MB (2007) Tau phosphorylation sites work in concert to promote neurotoxicity in vivo. Mol Biol Cell 18: 5060-5068.
-
(2007)
Mol Biol Cell
, vol.18
, pp. 5060-5068
-
-
Steinhilb, M.L.1
Dias-Santagata, D.2
Fulga, T.A.3
Felch, D.L.4
Feany, M.B.5
-
18
-
-
33947286683
-
Abnormal bundling and accumulation of F-actin mediates tau-induced neuronal degeneration in vivo
-
Fulga TA, Elson-Schwab I, Khurana V, Steinhilb ML, Spires TL, et al. (2007) Abnormal bundling and accumulation of F-actin mediates tau-induced neuronal degeneration in vivo. Nat Cell Biol 9: 139-148.
-
(2007)
Nat Cell Biol
, vol.9
, pp. 139-148
-
-
Fulga, T.A.1
Elson-Schwab, I.2
Khurana, V.3
Steinhilb, M.L.4
Spires, T.L.5
-
20
-
-
31944434543
-
TORmediated cell-cycle activation causes neurodegeneration in a Drosophila tauopathy model
-
Khurana V, Lu Y, Steinhilb ML, Oldham S, Shulman JM, et al. (2006) TORmediated cell-cycle activation causes neurodegeneration in a Drosophila tauopathy model. Curr Biol 16: 230-241.
-
(2006)
Curr Biol
, vol.16
, pp. 230-241
-
-
Khurana, V.1
Lu, Y.2
Steinhilb, M.L.3
Oldham, S.4
Shulman, J.M.5
-
21
-
-
0027160708
-
Targeted gene expression as a means of altering cell fates and generating dominant phenotypes
-
Brand AH, Perrimon N (1993) Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118: 401-415.
-
(1993)
Development
, vol.118
, pp. 401-415
-
-
Brand, A.H.1
Perrimon, N.2
-
22
-
-
33846219134
-
Unfolded protein response in a Drosophila model for retinal degeneration
-
Ryoo HD, Domingos PM, Kang MJ, Steller H (2007) Unfolded protein response in a Drosophila model for retinal degeneration. EMBO J 26: 242-252.
-
(2007)
EMBO J
, vol.26
, pp. 242-252
-
-
Ryoo, H.D.1
Domingos, P.M.2
Kang, M.J.3
Steller, H.4
-
23
-
-
0346361872
-
Genetic modifiers of tauopathy in Drosophila
-
Shulman JM, Feany MB (2003) Genetic modifiers of tauopathy in Drosophila. Genetics 165: 1233-1242.
-
(2003)
Genetics
, vol.165
, pp. 1233-1242
-
-
Shulman, J.M.1
Feany, M.B.2
-
24
-
-
33749000311
-
Local caspase activity directs engulfment of dendrites during pruning
-
Williams DW, Kondo S, Krzyzanowska A, Hiromi Y, Truman JW (2006) Local caspase activity directs engulfment of dendrites during pruning. Nat Neurosci 9: 1234-1236.
-
(2006)
Nat Neurosci
, vol.9
, pp. 1234-1236
-
-
Williams, D.W.1
Kondo, S.2
Krzyzanowska, A.3
Hiromi, Y.4
Truman, J.W.5
-
25
-
-
70350131291
-
Suppression of retinal degeneration in Drosophila by stimulation of ER-associated degradation
-
Kang MJ, Ryoo HD (2009) Suppression of retinal degeneration in Drosophila by stimulation of ER-associated degradation. Proc Natl Acad Sci U S A 106: 17043-17048.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 17043-17048
-
-
Kang, M.J.1
Ryoo, H.D.2
-
26
-
-
65649146419
-
ER stress protects from retinal degeneration
-
Mendes CS, Levet C, Chatelain G, Dourlen P, Fouillet A, Dichtel-Danjoy ML, Gambis A, Ryoo HD, Steller H, Mollereau B (2009) ER stress protects from retinal degeneration. EMBO J 28: 1296-1307.
-
(2009)
EMBO J
, vol.28
, pp. 1296-1307
-
-
Mendes, C.S.1
Levet, C.2
Chatelain, G.3
Dourlen, P.4
Fouillet, A.5
Dichtel-Danjoy, M.L.6
Gambis, A.7
Ryoo, H.D.8
Steller, H.9
Mollereau, B.10
-
27
-
-
0033535553
-
Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity
-
Wolfe MS, Xia W, Ostaszewski BL, Diehl TS, Kimberly WT, Selkoe DJ (1999) Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity. Nature 398: 513-517.
-
(1999)
Nature
, vol.398
, pp. 513-517
-
-
Wolfe, M.S.1
Xia, W.2
Ostaszewski, B.L.3
Diehl, T.S.4
Kimberly, W.T.5
Selkoe, D.J.6
-
28
-
-
33748140720
-
Presenilins form ER Ca2+ leak channels, a function disrupted by familial Alzheimer's disease-linked mutations
-
Tu H, Nelson O, Bezprozvanny A, Wang Z, Lee SF, Hao YH, Serneels L, De Strooper B, Yu G, Bezprozvanny I (2006) Presenilins form ER Ca2+ leak channels, a function disrupted by familial Alzheimer's disease-linked mutations. Cell 126: 981-993.
-
(2006)
Cell
, vol.126
, pp. 981-993
-
-
Tu, H.1
Nelson, O.2
Bezprozvanny, A.3
Wang, Z.4
Lee, S.F.5
Hao, Y.H.6
Serneels, L.7
De Strooper, B.8
Yu, G.9
Bezprozvanny, I.10
-
29
-
-
33646183455
-
The control of endoplasmic reticuluminitiated apoptosis by the BCL-2 family of proteins
-
Oakes SA, Lin SS, Bassik MC (2006) The control of endoplasmic reticuluminitiated apoptosis by the BCL-2 family of proteins. Curr Mol Med 6: 99-109.
-
(2006)
Curr Mol Med
, vol.6
, pp. 99-109
-
-
Oakes, S.A.1
Lin, S.S.2
Bassik, M.C.3
-
30
-
-
67049172152
-
The endoplasmic reticulum stress response and aging
-
Naidoo N (2009) The endoplasmic reticulum stress response and aging. Rev Neurosci 20: 23-37.
-
(2009)
Rev Neurosci
, vol.20
, pp. 23-37
-
-
Naidoo, N.1
-
31
-
-
5744248243
-
Comparison of pathways controlling toxicity in the eye and brain in Drosophila models of human neurodegenerative diseases
-
Ghosh S, Feany MB (2004) Comparison of pathways controlling toxicity in the eye and brain in Drosophila models of human neurodegenerative diseases. Hum Mol Genet 3: 2011-2018.
-
(2004)
Hum Mol Genet
, vol.3
, pp. 2011-2018
-
-
Ghosh, S.1
Feany, M.B.2
-
32
-
-
20044367108
-
Cell-cycle reentry and cell death in transgenic mice expressing nonmutant human tau isoforms
-
Andorfer C, Acker CM, Kress Y, Hof PR, Duff K, et al. (2005) Cell-cycle reentry and cell death in transgenic mice expressing nonmutant human tau isoforms. J Neurosci 25: 5446-5454.
-
(2005)
J Neurosci
, vol.25
, pp. 5446-5454
-
-
Andorfer, C.1
Acker, C.M.2
Kress, Y.3
Hof, P.R.4
Duff, K.5
-
33
-
-
70349705552
-
AAV-tau mediates pyramidal neurodegeneration by cell-cycle re-entry without neurofibrillary tangle formation in wild-type mice
-
Jaworski T, Dewachter I, Lechat B, Croes S, Termont A, et al. (2009) AAV-tau mediates pyramidal neurodegeneration by cell-cycle re-entry without neurofibrillary tangle formation in wild-type mice. PLoS One 4: e7280.
-
(2009)
PLoS One
, vol.4
-
-
Jaworski, T.1
Dewachter, I.2
Lechat, B.3
Croes, S.4
Termont, A.5
-
34
-
-
0032522911
-
Ectopic cell cycle proteins predict the sites of neuronal cell death in Alzheimer's disease brain
-
Busser J, Geldmacher DS, Herrup K (1998) Ectopic cell cycle proteins predict the sites of neuronal cell death in Alzheimer's disease brain. J Neurosci 18: 2801-2807.
-
(1998)
J Neurosci
, vol.18
, pp. 2801-2807
-
-
Busser, J.1
Geldmacher, D.S.2
Herrup, K.3
-
35
-
-
33744985455
-
Endoplasmic reticulum stress features are prominent in Alzheimer disease but not in prion diseases in vivo
-
Unterberger U, Höftberger R, Gelpi E, Flicker H, Budka H, Voigtländer T (2006) Endoplasmic reticulum stress features are prominent in Alzheimer disease but not in prion diseases in vivo. J Neuropathol Exp Neurol 65: 348-357.
-
(2006)
J Neuropathol Exp Neurol
, vol.65
, pp. 348-357
-
-
Unterberger, U.1
Höftberger, R.2
Gelpi, E.3
Flicker, H.4
Budka, H.5
Voigtländer, T.6
-
36
-
-
70349627027
-
XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy
-
Hetz C, Thielen P, Matus S, Nassif M, Court F, Kiffin R, Martinez G, Cuervo AM, Brown RH, Glimcher LH (2009) XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy. Genes Dev 23: 2294-306.
-
(2009)
Genes Dev
, vol.23
, pp. 2294-2306
-
-
Hetz, C.1
Thielen, P.2
Matus, S.3
Nassif, M.4
Court, F.5
Kiffin, R.6
Martinez, G.7
Cuervo, A.M.8
Brown, R.H.9
Glimcher, L.H.10
|