-
1
-
-
84986551385
-
Age-related deficits in skeletal muscle recovery following disuse are associated with neuromuscular junction instability and ER stress, not impaired protein synthesis
-
Baehr, L. M., West, D. W., Marcotte, G., Marshall, A. G., De Sousa, L. G., Baar, K., et al. (2016). Age-related deficits in skeletal muscle recovery following disuse are associated with neuromuscular junction instability and ER stress, not impaired protein synthesis. Aging (Albany. NY). 8, 127-146. doi: 10.18632/aging.100879
-
(2016)
Aging (Albany. NY)
, vol.8
, pp. 127-146
-
-
Baehr, L.M.1
West, D.W.2
Marcotte, G.3
Marshall, A.G.4
De Sousa, L.G.5
Baar, K.6
-
2
-
-
39349083915
-
Adapting proteostasis for disease intervention
-
Balch, W. E., Morimoto, R. I., Dillin, A., and Kelly, J. W. (2008). Adapting proteostasis for disease intervention. Science 319, 916-919. doi: 10.1126/science.1141448
-
(2008)
Science
, vol.319
, pp. 916-919
-
-
Balch, W.E.1
Morimoto, R.I.2
Dillin, A.3
Kelly, J.W.4
-
3
-
-
70349266064
-
Collapse of proteostasis represents an early molecular event in Caenorhabditis elegans aging
-
Ben-Zvi, A., Miller, E. A., and Morimoto, R. I. (2009). Collapse of proteostasis represents an early molecular event in Caenorhabditis elegans aging. Proc. Natl. Acad. Sci. U.S.A. 106, 14914-14919. doi: 10.1073/pnas.0902882106
-
(2009)
Proc. Natl. Acad. Sci. U.S.A
, vol.106
, pp. 14914-14919
-
-
Ben-Zvi, A.1
Miller, E.A.2
Morimoto, R.I.3
-
4
-
-
84925536277
-
Increased endoplasmic reticulum stress in mouse osteocytes with aging alters Cox-2 response to mechanical stimuli
-
Chalil, S., Jaspers, R. T., Manders, R. J., Klein-Nulend, J., Bakker, A. D., and Deldicque, L. (2015). Increased endoplasmic reticulum stress in mouse osteocytes with aging alters Cox-2 response to mechanical stimuli. Calcif. Tissue Int. 96, 123-128. doi: 10.1007/s00223-014-9944-6
-
(2015)
Calcif. Tissue Int
, vol.96
, pp. 123-128
-
-
Chalil, S.1
Jaspers, R.T.2
Manders, R.J.3
Klein-Nulend, J.4
Bakker, A.D.5
Deldicque, L.6
-
5
-
-
84886246257
-
Characterization of global gene expression during assurance of lifespan extension by caloric restriction in budding yeast
-
Choi, K. M., Kwon, Y. Y., and Lee, C. K. (2013). Characterization of global gene expression during assurance of lifespan extension by caloric restriction in budding yeast. Exp. Gerontol. 48, 1455-1468. doi: 10.1016/j.exger.2013.10.001
-
(2013)
Exp. Gerontol
, vol.48
, pp. 1455-1468
-
-
Choi, K.M.1
Kwon, Y.Y.2
Lee, C.K.3
-
6
-
-
84928910731
-
PMT1 deficiency enhances basal UPR activity and extends replicative lifespan of Saccharomyces cerevisiae
-
Cui, H. J., Liu, X. G., McCormick, M., Wasko, B. M., Zhao, W., He, X., et al. (2015). PMT1 deficiency enhances basal UPR activity and extends replicative lifespan of Saccharomyces cerevisiae. Age (Dordr). 37, 9788. doi: 10.1007/s11357-015-9788-7
-
(2015)
Age (Dordr)
, vol.37
, pp. 9788
-
-
Cui, H.J.1
Liu, X.G.2
McCormick, M.3
Wasko, B.M.4
Zhao, W.5
He, X.6
-
7
-
-
77956362155
-
Protein homeostasis and aging in neurodegeneration
-
Douglas, P. M., and Dillin, A. (2010). Protein homeostasis and aging in neurodegeneration. J. Cell Biol. 190, 719-729. doi: 10.1083/jcb.201005144
-
(2010)
J. Cell Biol
, vol.190
, pp. 719-729
-
-
Douglas, P.M.1
Dillin, A.2
-
8
-
-
74049104138
-
Dysfunction of the unfolded protein response increases neurodegeneration in aged rat hippocampus following proteasome inhibition
-
Gavilan, M. P., Pintado, C., Gavilan, E., Jimenez, S., Rios, R. M., Vitorica, J., et al. (2009). Dysfunction of the unfolded protein response increases neurodegeneration in aged rat hippocampus following proteasome inhibition. Aging Cell 8, 654-665. doi: 10.1111/j.1474-9726.2009.00519.x
-
(2009)
Aging Cell
, vol.8
, pp. 654-665
-
-
Gavilan, M.P.1
Pintado, C.2
Gavilan, E.3
Jimenez, S.4
Rios, R.M.5
Vitorica, J.6
-
9
-
-
84946550842
-
Elevated endoplasmic reticulum stress response contributes to adipose tissue inflammation in aging
-
Ghosh, A. K., Garg, S. K., Mau, T., O'Brien, M., Liu, J., and Yung, R. (2015). Elevated endoplasmic reticulum stress response contributes to adipose tissue inflammation in aging. J. Gerontol. A Biol. Sci. Med. Sci. 70, 1320-1329. doi: 10.1093/gerona/glu186
-
(2015)
J. Gerontol. A Biol. Sci. Med. Sci
, vol.70
, pp. 1320-1329
-
-
Ghosh, A.K.1
Garg, S.K.2
Mau, T.3
O'Brien, M.4
Liu, J.5
Yung, R.6
-
10
-
-
77953091249
-
Insulin/IGF-1 signaling mutants reprogram ER stress response regulators to promote longevity
-
Henis-Korenblit, S., Zhang, P., Hansen, M., McCormick, M., Lee, S. J., Cary, M., et al. (2010). Insulin/IGF-1 signaling mutants reprogram ER stress response regulators to promote longevity. Proc. Natl. Acad. Sci. U.S.A. 107, 9730-9735. doi: 10.1073/pnas.1002575107
-
(2010)
Proc. Natl. Acad. Sci. U.S.A
, vol.107
, pp. 9730-9735
-
-
Henis-Korenblit, S.1
Zhang, P.2
Hansen, M.3
McCormick, M.4
Lee, S.J.5
Cary, M.6
-
11
-
-
84883387793
-
Targeting the unfolded protein response in disease
-
Hetz, C., Chevet, E., and Harding, H. P. (2013). Targeting the unfolded protein response in disease. Nat. Rev. Drug Discov. 12, 703-719. doi: 10.1038/nrd3976
-
(2013)
Nat. Rev. Drug Discov
, vol.12
, pp. 703-719
-
-
Hetz, C.1
Chevet, E.2
Harding, H.P.3
-
12
-
-
84934275896
-
Proteostasis control by the unfolded protein response
-
Hetz, C., Chevet, E., and Oakes, S. A. (2015). Proteostasis control by the unfolded protein response. Nat. Cell Biol. 17, 829-838. doi: 10.1038/ncb3184
-
(2015)
Nat. Cell Biol
, vol.17
, pp. 829-838
-
-
Hetz, C.1
Chevet, E.2
Oakes, S.A.3
-
13
-
-
84897094564
-
Disturbance of endoplasmic reticulum proteostasis in neurodegenerative diseases
-
Hetz, C., and Mollereau, B. (2014). Disturbance of endoplasmic reticulum proteostasis in neurodegenerative diseases. Nat. Rev. Neurosci. 15, 1-19. doi: 10.1038/nrn3689
-
(2014)
Nat. Rev. Neurosci
, vol.15
, pp. 1-19
-
-
Hetz, C.1
Mollereau, B.2
-
14
-
-
84971602791
-
Age-related changes in the transcriptome of antibody-secreting cells
-
Kannan, S., Dawany, N., Kurupati, R., Showe, L. C., and Ertl, H. C. (2016). Age-related changes in the transcriptome of antibody-secreting cells. Oncotarget 7, 13340-13353. doi: 10.18632/oncotarget.7958
-
(2016)
Oncotarget
, vol.7
, pp. 13340-13353
-
-
Kannan, S.1
Dawany, N.2
Kurupati, R.3
Showe, L.C.4
Ertl, H.C.5
-
15
-
-
84949559900
-
Proteostasis and aging
-
Kaushik, S., and Cuervo, A. M. (2015). Proteostasis and aging. Nat. Med. 21, 1406-1415. doi: 10.1038/nm.4001
-
(2015)
Nat. Med
, vol.21
, pp. 1406-1415
-
-
Kaushik, S.1
Cuervo, A.M.2
-
16
-
-
84910029849
-
Geroscience: linking aging to chronic disease
-
Kennedy, B. K., Berger, S. L., Brunet, A., Campisi, J., Cuervo, A. M., Epel, E. S., et al. (2014). Geroscience: linking aging to chronic disease. Cell 159, 709-713. doi: 10.1016/j.cell.2014.10.039
-
(2014)
Cell
, vol.159
, pp. 709-713
-
-
Kennedy, B.K.1
Berger, S.L.2
Brunet, A.3
Campisi, J.4
Cuervo, A.M.5
Epel, E.S.6
-
17
-
-
84941731816
-
Proteotoxic stress and ageing triggers the loss of redox homeostasis across cellular compartments
-
Kirstein, J., Morito, D., Kakihana, T., Sugihara, M., Minnen, A., Hipp, M. S., et al. (2015). Proteotoxic stress and ageing triggers the loss of redox homeostasis across cellular compartments. EMBO J. 34, 2334-2349. doi: 10.15252/embj.201591711
-
(2015)
EMBO J
, vol.34
, pp. 2334-2349
-
-
Kirstein, J.1
Morito, D.2
Kakihana, T.3
Sugihara, M.4
Minnen, A.5
Hipp, M.S.6
-
18
-
-
84896726774
-
Lifespan extension conferred by endoplasmic reticulum secretory pathway deficiency requires induction of the unfolded protein response
-
Labunskyy, V. M., Gerashchenko, M. V., Delaney, J. R., Kaya, A., Kennedy, B. K., Kaeberlein, M., et al. (2014). Lifespan extension conferred by endoplasmic reticulum secretory pathway deficiency requires induction of the unfolded protein response. PLoS Genet. 10:e1004019. doi: 10.1371/journal.pgen.1004019
-
(2014)
PLoS Genet
, vol.10
-
-
Labunskyy, V.M.1
Gerashchenko, M.V.2
Delaney, J.R.3
Kaya, A.4
Kennedy, B.K.5
Kaeberlein, M.6
-
19
-
-
84944705075
-
Unfolded protein response is activated in aged retinas
-
Lenox, A. R., Bhootada, Y., Gorbatyuk, O., Fullard, R., and Gorbatyuk, M. (2015). Unfolded protein response is activated in aged retinas. Neurosci. Lett. 609, 30-35. doi: 10.1016/j.neulet.2015.10.019
-
(2015)
Neurosci. Lett
, vol.609
, pp. 30-35
-
-
Lenox, A.R.1
Bhootada, Y.2
Gorbatyuk, O.3
Fullard, R.4
Gorbatyuk, M.5
-
20
-
-
84878864199
-
The hallmarks of aging
-
Lopez-Otin, C., Blasco, M. A., Partridge, L., Serrano, M., and Kroemer, G. (2013). The hallmarks of aging. Cell 153, 1194-1217. doi: 10.1016/j.cell.2013.05.039
-
(2013)
Cell
, vol.153
, pp. 1194-1217
-
-
Lopez-Otin, C.1
Blasco, M.A.2
Partridge, L.3
Serrano, M.4
Kroemer, G.5
-
21
-
-
84918547483
-
Control of systemic proteostasis by the nervous system
-
Mardones, P., Martinez, G., and Hetz, C. (2015). Control of systemic proteostasis by the nervous system. Trends Cell Biol. 25, 1-10. doi: 10.1016/j.tcb.2014.08.001
-
(2015)
Trends Cell Biol
, vol.25
, pp. 1-10
-
-
Mardones, P.1
Martinez, G.2
Hetz, C.3
-
22
-
-
84958124223
-
Regulation of memory formation by the transcription factor XBP1
-
Martinez, G., Vidal, R. L., Mardones, P., Serrano, F. G., Ardiles, A. O., Wirth, C., et al. (2016). Regulation of memory formation by the transcription factor XBP1. Cell Rep. 14, 1382-1394. doi: 10.1016/j.celrep.2016.01.028
-
(2016)
Cell Rep
, vol.14
, pp. 1382-1394
-
-
Martinez, G.1
Vidal, R.L.2
Mardones, P.3
Serrano, F.G.4
Ardiles, A.O.5
Wirth, C.6
-
23
-
-
48549090526
-
Aging impairs the unfolded protein response to sleep deprivation and leads to proapoptotic signaling
-
Naidoo, N., Ferber, M., Master, M., Zhu, Y., and Pack, A. I. (2008). Aging impairs the unfolded protein response to sleep deprivation and leads to proapoptotic signaling. J. Neurosci. 28, 6539-6548. doi: 10.1523/JNEUROSCI.5685-07.2008
-
(2008)
J. Neurosci
, vol.28
, pp. 6539-6548
-
-
Naidoo, N.1
Ferber, M.2
Master, M.3
Zhu, Y.4
Pack, A.I.5
-
24
-
-
84943612670
-
Regulation of the unfolded protein response via S-nitrosylation of sensors of endoplasmic reticulum stress
-
Nakato, R., Ohkubo, Y., Konishi, A., Shibata, M., Kaneko, Y., Iwawaki, T., et al. (2015). Regulation of the unfolded protein response via S-nitrosylation of sensors of endoplasmic reticulum stress. Sci. Rep. 5:14812. doi: 10.1038/srep14812
-
(2015)
Sci. Rep
, vol.5
, pp. 14812
-
-
Nakato, R.1
Ohkubo, Y.2
Konishi, A.3
Shibata, M.4
Kaneko, Y.5
Iwawaki, T.6
-
25
-
-
33646512882
-
Cellular environment facilitates protein accumulation in aged rat hippocampus
-
Paz Gavilan, M., Vela, J., Castano, A., Ramos, B., del Rio, J. C., Vitorica, J., et al. (2006). Cellular environment facilitates protein accumulation in aged rat hippocampus. Neurobiol. Aging 27, 973-982. doi: 10.1016/j.neurobiolaging.2005.05.010
-
(2006)
Neurobiol. Aging
, vol.27
, pp. 973-982
-
-
Paz Gavilan, M.1
Vela, J.2
Castano, A.3
Ramos, B.4
del Rio, J.C.5
Vitorica, J.6
-
26
-
-
34250899722
-
Signal integration in the endoplasmic reticulum unfolded protein response
-
Ron, D., and Walter, P. (2007). Signal integration in the endoplasmic reticulum unfolded protein response. Nat. Rev. Mol. Cell Biol. 8, 519-529. doi: 10.1038/nrm2199
-
(2007)
Nat. Rev. Mol. Cell Biol
, vol.8
, pp. 519-529
-
-
Ron, D.1
Walter, P.2
-
27
-
-
84883773783
-
Inhibition of x-box binding protein 1 reduces tunicamycin-induced apoptosis in aged murine macrophages
-
Song, Y., Shen, H., Du, W., and Goldstein, D. R. (2013). Inhibition of x-box binding protein 1 reduces tunicamycin-induced apoptosis in aged murine macrophages. Aging Cell 12, 794-801. doi: 10.1111/acel.12105
-
(2013)
Aging Cell
, vol.12
, pp. 794-801
-
-
Song, Y.1
Shen, H.2
Du, W.3
Goldstein, D.R.4
-
28
-
-
84865725097
-
Organismal regulation of XBP-1-mediated unfolded protein response during development and immune activation
-
Sun, J., Liu, Y., and Aballay, A. (2012). Organismal regulation of XBP-1-mediated unfolded protein response during development and immune activation. EMBO Rep. 13, 855-860. doi: 10.1038/embor.2012.100
-
(2012)
EMBO Rep
, vol.13
, pp. 855-860
-
-
Sun, J.1
Liu, Y.2
Aballay, A.3
-
29
-
-
84879343155
-
XBP-1 is a cell-nonautonomous regulator of stress resistance and longevity
-
Taylor, R. C., and Dillin, A. (2013). XBP-1 is a cell-nonautonomous regulator of stress resistance and longevity. Cell 153, 1435-1447. doi: 10.1016/j.cell.2013.05.042
-
(2013)
Cell
, vol.153
, pp. 1435-1447
-
-
Taylor, R.C.1
Dillin, A.2
-
30
-
-
84930787599
-
PERK limits Drosophila lifespan by promoting intestinal stem cell proliferation in response to ER Stress
-
Wang, L., Ryoo, H. D., Qi, Y., and Jasper, H. (2015). PERK limits Drosophila lifespan by promoting intestinal stem cell proliferation in response to ER Stress. PLoS Genet. 11:e1005220. doi: 10.1371/journal.pgen.1005220
-
(2015)
PLoS Genet
, vol.11
-
-
Wang, L.1
Ryoo, H.D.2
Qi, Y.3
Jasper, H.4
-
31
-
-
84918835614
-
Integration of UPRER and oxidative stress signaling in the control of intestinal stem cell proliferation
-
Wang, L., Zeng, X., Ryoo, H. D., and Jasper, H. (2014). Integration of UPRER and oxidative stress signaling in the control of intestinal stem cell proliferation. PLoS Genet. 10:e1004568. doi: 10.1371/journal.pgen.1004568
-
(2014)
PLoS Genet
, vol.10
-
-
Wang, L.1
Zeng, X.2
Ryoo, H.D.3
Jasper, H.4
-
32
-
-
84913530022
-
Xbp1s in Pomc neurons connects ER stress with energy balance and glucose homeostasis
-
Williams, K. W., Liu, T., Kong, X., Fukuda, M., Deng, Y., Berglund, E. D., et al. (2014). Xbp1s in Pomc neurons connects ER stress with energy balance and glucose homeostasis. Cell Metab. 20, 471-482. doi: 10.1016/j.cmet.2014.06.002
-
(2014)
Cell Metab
, vol.20
, pp. 471-482
-
-
Williams, K.W.1
Liu, T.2
Kong, X.3
Fukuda, M.4
Deng, Y.5
Berglund, E.D.6
|