-
1
-
-
0036877142
-
The endoplasmic reticulum: a multifunctional signaling organelle
-
Berridge M.J. The endoplasmic reticulum: a multifunctional signaling organelle. Cell Calcium 2002, 32:235-249.
-
(2002)
Cell Calcium
, vol.32
, pp. 235-249
-
-
Berridge, M.J.1
-
2
-
-
84856111924
-
The unfolded protein response: controlling cell fate decisions under ER stress and beyond
-
Hetz C. The unfolded protein response: controlling cell fate decisions under ER stress and beyond. Nat. Rev. Mol. Cell Biol. 2012, 13:89-102.
-
(2012)
Nat. Rev. Mol. Cell Biol.
, vol.13
, pp. 89-102
-
-
Hetz, C.1
-
3
-
-
82255173966
-
The unfolded protein response: from stress pathway to homeostatic regulation
-
Walter P., Ron D. The unfolded protein response: from stress pathway to homeostatic regulation. Science 2011, 334:1081-1086.
-
(2011)
Science
, vol.334
, pp. 1081-1086
-
-
Walter, P.1
Ron, D.2
-
4
-
-
79952264011
-
Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress
-
Tabas I., Ron D. Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress. Nat. Cell Biol. 2011, 13:184-190.
-
(2011)
Nat. Cell Biol.
, vol.13
, pp. 184-190
-
-
Tabas, I.1
Ron, D.2
-
5
-
-
79958033194
-
Modulating stress responses by the UPRosome: a matter of life and death
-
Woehlbier U., Hetz C. Modulating stress responses by the UPRosome: a matter of life and death. Trends Biochem. Sci. 2011, 36:329-337.
-
(2011)
Trends Biochem. Sci.
, vol.36
, pp. 329-337
-
-
Woehlbier, U.1
Hetz, C.2
-
6
-
-
79954426157
-
Signaling cell death from the endoplasmic reticulum stress response
-
Shore G.C., Papa F.R., Oakes S.A. Signaling cell death from the endoplasmic reticulum stress response. Curr. Opin. Cell Biol. 2011, 23:143-149.
-
(2011)
Curr. Opin. Cell Biol.
, vol.23
, pp. 143-149
-
-
Shore, G.C.1
Papa, F.R.2
Oakes, S.A.3
-
7
-
-
79952705597
-
Integrating stress signals at the endoplasmic reticulum: the BCL-2 protein family rheostat
-
Rodriguez D., Rojas-Rivera D., Hetz C. Integrating stress signals at the endoplasmic reticulum: the BCL-2 protein family rheostat. Biochim. Biophys. Acta 2011, 1813:564-574.
-
(2011)
Biochim. Biophys. Acta
, vol.1813
, pp. 564-574
-
-
Rodriguez, D.1
Rojas-Rivera, D.2
Hetz, C.3
-
8
-
-
34250899722
-
Signal integration in the endoplasmic reticulum unfolded protein response
-
Ron D., Walter P. Signal integration in the endoplasmic reticulum unfolded protein response. Nat. Rev. Mol. Cell Biol. 2007, 8:519-529.
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 519-529
-
-
Ron, D.1
Walter, P.2
-
9
-
-
0032693671
-
Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress
-
Haze K., Yoshida H., Yanagi H., Yura T., Mori K. Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress. Mol. Biol. Cell 1999, 10:3787-3799.
-
(1999)
Mol. Biol. Cell
, vol.10
, pp. 3787-3799
-
-
Haze, K.1
Yoshida, H.2
Yanagi, H.3
Yura, T.4
Mori, K.5
-
10
-
-
79955424672
-
The signalling from endoplasmic reticulum-resident bZIP transcription factors involved in diverse cellular physiology
-
Asada R., Kanemoto S., Kondo S., Saito A., Imaizumi K. The signalling from endoplasmic reticulum-resident bZIP transcription factors involved in diverse cellular physiology. J. Biochem. 2011, 149:507-518.
-
(2011)
J. Biochem.
, vol.149
, pp. 507-518
-
-
Asada, R.1
Kanemoto, S.2
Kondo, S.3
Saito, A.4
Imaizumi, K.5
-
11
-
-
0033634654
-
Regulated translation initiation controls stress-induced gene expression in mammalian cells
-
Harding H.P., Novoa I., Zhang Y., Zeng H., Wek R., Schapira M., Ron D. Regulated translation initiation controls stress-induced gene expression in mammalian cells. Mol. Cell 2000, 6:1099-1108.
-
(2000)
Mol. Cell
, vol.6
, pp. 1099-1108
-
-
Harding, H.P.1
Novoa, I.2
Zhang, Y.3
Zeng, H.4
Wek, R.5
Schapira, M.6
Ron, D.7
-
12
-
-
3843117589
-
Reinitiation involving upstream ORFs regulates ATF4 mRNA translation in mammalian cells
-
Vattem K.M., Wek R.C. Reinitiation involving upstream ORFs regulates ATF4 mRNA translation in mammalian cells. Proc. Natl. Acad. Sci. U. S. A. 2004, 101:11269-11274.
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 11269-11274
-
-
Vattem, K.M.1
Wek, R.C.2
-
13
-
-
0037353039
-
An integrated stress response regulates amino acid metabolism and resistance to oxidative stress
-
Harding H.P., Zhang Y., Zeng H., Novoa I., Lu P.D., Calfon M., Sadri N., Yun C., Popko B., Paules R., Stojdl D.F., Bell J.C., Hettmann T., Leiden J.M., Ron D. An integrated stress response regulates amino acid metabolism and resistance to oxidative stress. Mol. Cell 2003, 11:619-633.
-
(2003)
Mol. Cell
, vol.11
, pp. 619-633
-
-
Harding, H.P.1
Zhang, Y.2
Zeng, H.3
Novoa, I.4
Lu, P.D.5
Calfon, M.6
Sadri, N.7
Yun, C.8
Popko, B.9
Paules, R.10
Stojdl, D.F.11
Bell, J.C.12
Hettmann, T.13
Leiden, J.M.14
Ron, D.15
-
14
-
-
0035234534
-
Ire1p: a kinase and site-specific endoribonuclease
-
Gonzalez T.N., Walter P. Ire1p: a kinase and site-specific endoribonuclease. Methods Mol. Biol. 2001, 160:25-36.
-
(2001)
Methods Mol. Biol.
, vol.160
, pp. 25-36
-
-
Gonzalez, T.N.1
Walter, P.2
-
15
-
-
0037011917
-
IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA
-
Calfon M., Zeng H., Urano F., Till J.H., Hubbard S.R., Harding H.P., Clark S.G., Ron D. IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA. Nature 2002, 415:92-96.
-
(2002)
Nature
, vol.415
, pp. 92-96
-
-
Calfon, M.1
Zeng, H.2
Urano, F.3
Till, J.H.4
Hubbard, S.R.5
Harding, H.P.6
Clark, S.G.7
Ron, D.8
-
16
-
-
34250794495
-
XBP1 controls diverse cell type- and condition-specific transcriptional regulatory networks
-
Acosta-Alvear D., Zhou Y., Blais A., Tsikitis M., Lents N.H., Arias C., Lennon C.J., Kluger Y., Dynlacht B.D. XBP1 controls diverse cell type- and condition-specific transcriptional regulatory networks. Mol. Cell 2007, 27:53-66.
-
(2007)
Mol. Cell
, vol.27
, pp. 53-66
-
-
Acosta-Alvear, D.1
Zhou, Y.2
Blais, A.3
Tsikitis, M.4
Lents, N.H.5
Arias, C.6
Lennon, C.J.7
Kluger, Y.8
Dynlacht, B.D.9
-
17
-
-
0142059951
-
XBP-1 regulates a subset of endoplasmic reticulum resident chaperone genes in the unfolded protein response
-
Lee A.H., Iwakoshi N.N., Glimcher L.H. XBP-1 regulates a subset of endoplasmic reticulum resident chaperone genes in the unfolded protein response. Mol. Cell. Biol. 2003, 23:7448-7459.
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 7448-7459
-
-
Lee, A.H.1
Iwakoshi, N.N.2
Glimcher, L.H.3
-
18
-
-
78649338141
-
Autophagy and the integrated stress response
-
Kroemer G., Marino G., Levine B. Autophagy and the integrated stress response. Mol. Cell 2010, 40:280-293.
-
(2010)
Mol. Cell
, vol.40
, pp. 280-293
-
-
Kroemer, G.1
Marino, G.2
Levine, B.3
-
19
-
-
33845459165
-
Autophagy is activated for cell survival after endoplasmic reticulum stress
-
Ogata M., Hino S., Saito A., Morikawa K., Kondo S., Kanemoto S., Murakami T., Taniguchi M., Tanii I., Yoshinaga K., Shiosaka S., Hammarback J.A., Urano F., Imaizumi K. Autophagy is activated for cell survival after endoplasmic reticulum stress. Mol. Cell. Biol. 2006, 26:9220-9231.
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 9220-9231
-
-
Ogata, M.1
Hino, S.2
Saito, A.3
Morikawa, K.4
Kondo, S.5
Kanemoto, S.6
Murakami, T.7
Taniguchi, M.8
Tanii, I.9
Yoshinaga, K.10
Shiosaka, S.11
Hammarback, J.A.12
Urano, F.13
Imaizumi, K.14
-
20
-
-
84859799949
-
Stress management at the ER: regulators of ER stress-induced apoptosis
-
Gorman A.M., Healy S.J., Jager R., Samali A. Stress management at the ER: regulators of ER stress-induced apoptosis. Pharmacol. Ther. 2012, 134:306-316.
-
(2012)
Pharmacol. Ther.
, vol.134
, pp. 306-316
-
-
Gorman, A.M.1
Healy, S.J.2
Jager, R.3
Samali, A.4
-
21
-
-
27144458505
-
ER stress-regulated translation increases tolerance to extreme hypoxia and promotes tumor growth
-
Bi M., Naczki C., Koritzinsky M., Fels D., Blais J., Hu N., Harding H., Novoa I., Varia M., Raleigh J., Scheuner D., Kaufman R.J., Bell J., Ron D., Wouters B.G., Koumenis C. ER stress-regulated translation increases tolerance to extreme hypoxia and promotes tumor growth. EMBO J. 2005, 24:3470-3481.
-
(2005)
EMBO J.
, vol.24
, pp. 3470-3481
-
-
Bi, M.1
Naczki, C.2
Koritzinsky, M.3
Fels, D.4
Blais, J.5
Hu, N.6
Harding, H.7
Novoa, I.8
Varia, M.9
Raleigh, J.10
Scheuner, D.11
Kaufman, R.J.12
Bell, J.13
Ron, D.14
Wouters, B.G.15
Koumenis, C.16
-
22
-
-
0036837864
-
Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alpha
-
Koumenis C., Naczki C., Koritzinsky M., Rastani S., Diehl A., Sonenberg N., Koromilas A., Wouters B.G. Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alpha. Mol. Cell. Biol. 2002, 22:7405-7416.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 7405-7416
-
-
Koumenis, C.1
Naczki, C.2
Koritzinsky, M.3
Rastani, S.4
Diehl, A.5
Sonenberg, N.6
Koromilas, A.7
Wouters, B.G.8
-
23
-
-
58449084895
-
Divergent effects of PERK and IRE1 signaling on cell viability
-
Lin J.H., Li H., Zhang Y., Ron D., Walter P. Divergent effects of PERK and IRE1 signaling on cell viability. PLoS One 2009, 4:e4170.
-
(2009)
PLoS One
, vol.4
-
-
Lin, J.H.1
Li, H.2
Zhang, Y.3
Ron, D.4
Walter, P.5
-
24
-
-
10644233167
-
CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum
-
Marciniak S.J., Yun C.Y., Oyadomari S., Novoa I., Zhang Y., Jungreis R., Nagata K., Harding H.P., Ron D. CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum. Genes Dev. 2004, 18:3066-3077.
-
(2004)
Genes Dev.
, vol.18
, pp. 3066-3077
-
-
Marciniak, S.J.1
Yun, C.Y.2
Oyadomari, S.3
Novoa, I.4
Zhang, Y.5
Jungreis, R.6
Nagata, K.7
Harding, H.P.8
Ron, D.9
-
25
-
-
0041703031
-
The function of GADD34 is a recovery from a shutoff of protein synthesis induced by ER stress: elucidation by GADD34-deficient mice
-
Kojima E., Takeuchi A., Haneda M., Yagi A., Hasegawa T., Yamaki K., Takeda K., Akira S., Shimokata K., Isobe K. The function of GADD34 is a recovery from a shutoff of protein synthesis induced by ER stress: elucidation by GADD34-deficient mice. FASEB J. 2003, 17:1573-1575.
-
(2003)
FASEB J.
, vol.17
, pp. 1573-1575
-
-
Kojima, E.1
Takeuchi, A.2
Haneda, M.3
Yagi, A.4
Hasegawa, T.5
Yamaki, K.6
Takeda, K.7
Akira, S.8
Shimokata, K.9
Isobe, K.10
-
26
-
-
84877578475
-
ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death
-
Han J., Back S.H., Hur J., Lin Y.H., Gildersleeve R., Shan J., Yuan C.L., Krokowski D., Wang S., Hatzoglou M., Kilberg M.S., Sartor M.A., Kaufman R.J. ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death. Nat. Cell Biol. 2013, 15:481-490.
-
(2013)
Nat. Cell Biol.
, vol.15
, pp. 481-490
-
-
Han, J.1
Back, S.H.2
Hur, J.3
Lin, Y.H.4
Gildersleeve, R.5
Shan, J.6
Yuan, C.L.7
Krokowski, D.8
Wang, S.9
Hatzoglou, M.10
Kilberg, M.S.11
Sartor, M.A.12
Kaufman, R.J.13
-
27
-
-
13644256191
-
A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress
-
Boyce M., Bryant K.F., Jousse C., Long K., Harding H.P., Scheuner D., Kaufman R.J., Ma D., Coen D.M., Ron D., Yuan J. A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress. Science 2005, 307:935-939.
-
(2005)
Science
, vol.307
, pp. 935-939
-
-
Boyce, M.1
Bryant, K.F.2
Jousse, C.3
Long, K.4
Harding, H.P.5
Scheuner, D.6
Kaufman, R.J.7
Ma, D.8
Coen, D.M.9
Ron, D.10
Yuan, J.11
-
28
-
-
79953288480
-
Selective inhibition of a regulatory subunit of protein phosphatase 1 restores proteostasis
-
Tsaytler P., Harding H.P., Ron D., Bertolotti A. Selective inhibition of a regulatory subunit of protein phosphatase 1 restores proteostasis. Science 2011, 332:91-94.
-
(2011)
Science
, vol.332
, pp. 91-94
-
-
Tsaytler, P.1
Harding, H.P.2
Ron, D.3
Bertolotti, A.4
-
29
-
-
0035144493
-
Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state
-
McCullough K.D., Martindale J.L., Klotz L.O., Aw T.Y., Holbrook N.J. Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state. Mol. Cell. Biol. 2001, 21:1249-1259.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 1249-1259
-
-
McCullough, K.D.1
Martindale, J.L.2
Klotz, L.O.3
Aw, T.Y.4
Holbrook, N.J.5
-
30
-
-
34250758642
-
ER stress triggers apoptosis by activating BH3-only protein Bim
-
Puthalakath H., O'Reilly L.A., Gunn P., Lee L., Kelly P.N., Huntington N.D., Hughes P.D., Michalak E.M., McKimm-Breschkin J., Motoyama N., Gotoh T., Akira S., Bouillet P., Strasser A. ER stress triggers apoptosis by activating BH3-only protein Bim. Cell 2007, 129:1337-1349.
-
(2007)
Cell
, vol.129
, pp. 1337-1349
-
-
Puthalakath, H.1
O'Reilly, L.A.2
Gunn, P.3
Lee, L.4
Kelly, P.N.5
Huntington, N.D.6
Hughes, P.D.7
Michalak, E.M.8
McKimm-Breschkin, J.9
Motoyama, N.10
Gotoh, T.11
Akira, S.12
Bouillet, P.13
Strasser, A.14
-
31
-
-
0042477717
-
Gene expression during ER stress-induced apoptosis in neurons: induction of the BH3-only protein Bbc3/PUMA and activation of the mitochondrial apoptosis pathway
-
Reimertz C., Kogel D., Rami A., Chittenden T., Prehn J.H. Gene expression during ER stress-induced apoptosis in neurons: induction of the BH3-only protein Bbc3/PUMA and activation of the mitochondrial apoptosis pathway. J. Cell Biol. 2003, 162:587-597.
-
(2003)
J. Cell Biol.
, vol.162
, pp. 587-597
-
-
Reimertz, C.1
Kogel, D.2
Rami, A.3
Chittenden, T.4
Prehn, J.H.5
-
32
-
-
77954370584
-
CHOP and AP-1 cooperatively mediate PUMA expression during lipoapoptosis
-
Cazanave S.C., Elmi N.A., Akazawa Y., Bronk S.F., Mott J.L., Gores G.J. CHOP and AP-1 cooperatively mediate PUMA expression during lipoapoptosis. Am. J. Physiol. Gastrointest. Liver Physiol. 2010, 299:G236-G243.
-
(2010)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.299
-
-
Cazanave, S.C.1
Elmi, N.A.2
Akazawa, Y.3
Bronk, S.F.4
Mott, J.L.5
Gores, G.J.6
-
33
-
-
84868564773
-
NOXA contributes to the sensitivity of PERK-deficient cells to ER stress
-
Gupta S., Giricz Z., Natoni A., Donnelly N., Deegan S., Szegezdi E., Samali A. NOXA contributes to the sensitivity of PERK-deficient cells to ER stress. FEBS Lett. 2012, 586:4023-4030.
-
(2012)
FEBS Lett.
, vol.586
, pp. 4023-4030
-
-
Gupta, S.1
Giricz, Z.2
Natoni, A.3
Donnelly, N.4
Deegan, S.5
Szegezdi, E.6
Samali, A.7
-
34
-
-
77955173081
-
Ablation of C/EBP homologous protein attenuates endoplasmic reticulum-mediated apoptosis and cardiac dysfunction induced by pressure overload
-
Fu H.Y., Okada K., Liao Y., Tsukamoto O., Isomura T., Asai M., Sawada T., Okuda K., Asano Y., Sanada S., Asanuma H., Asakura M., Takashima S., Komuro I., Kitakaze M., Minamino T. Ablation of C/EBP homologous protein attenuates endoplasmic reticulum-mediated apoptosis and cardiac dysfunction induced by pressure overload. Circulation 2010, 122:361-369.
-
(2010)
Circulation
, vol.122
, pp. 361-369
-
-
Fu, H.Y.1
Okada, K.2
Liao, Y.3
Tsukamoto, O.4
Isomura, T.5
Asai, M.6
Sawada, T.7
Okuda, K.8
Asano, Y.9
Sanada, S.10
Asanuma, H.11
Asakura, M.12
Takashima, S.13
Komuro, I.14
Kitakaze, M.15
Minamino, T.16
-
35
-
-
77956334107
-
Molecular mechanisms regulating oxidative activity of the Ero1 family in the endoplasmic reticulum
-
Tavender T.J., Bulleid N.J. Molecular mechanisms regulating oxidative activity of the Ero1 family in the endoplasmic reticulum. Antioxid. Redox Signal. 2010, 13:1177-1187.
-
(2010)
Antioxid. Redox Signal.
, vol.13
, pp. 1177-1187
-
-
Tavender, T.J.1
Bulleid, N.J.2
-
36
-
-
84880423261
-
Functional role of the transcription factor ATF4 in the pathogenesis of amyotrophic lateral sclerosis
-
Matus S., Lopez E., Valenzuela V., Nasiff M., Hetz C. Functional role of the transcription factor ATF4 in the pathogenesis of amyotrophic lateral sclerosis. PLoS One 2013, 8:e66672.
-
(2013)
PLoS One
, vol.8
-
-
Matus, S.1
Lopez, E.2
Valenzuela, V.3
Nasiff, M.4
Hetz, C.5
-
37
-
-
35848957485
-
Endoplasmic reticulum stress and oxidative stress: a vicious cycle or a double-edged sword?
-
Malhotra J.D., Kaufman R.J. Endoplasmic reticulum stress and oxidative stress: a vicious cycle or a double-edged sword?. Antioxid. Redox Signal. 2007, 9:2277-2293.
-
(2007)
Antioxid. Redox Signal.
, vol.9
, pp. 2277-2293
-
-
Malhotra, J.D.1
Kaufman, R.J.2
-
38
-
-
55849096988
-
Chop deletion reduces oxidative stress, improves beta cell function, and promotes cell survival in multiple mouse models of diabetes
-
Song B., Scheuner D., Ron D., Pennathur S., Kaufman R.J. Chop deletion reduces oxidative stress, improves beta cell function, and promotes cell survival in multiple mouse models of diabetes. J. Clin. Invest. 2008, 118:3378-3389.
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 3378-3389
-
-
Song, B.1
Scheuner, D.2
Ron, D.3
Pennathur, S.4
Kaufman, R.J.5
-
39
-
-
70349905357
-
Role of ERO1-alpha-mediated stimulation of inositol 1,4,5-triphosphate receptor activity in endoplasmic reticulum stress-induced apoptosis
-
Li G., Mongillo M., Chin K.T., Harding H., Ron D., Marks A.R., Tabas I. Role of ERO1-alpha-mediated stimulation of inositol 1,4,5-triphosphate receptor activity in endoplasmic reticulum stress-induced apoptosis. J. Cell Biol. 2009, 186:783-792.
-
(2009)
J. Cell Biol.
, vol.186
, pp. 783-792
-
-
Li, G.1
Mongillo, M.2
Chin, K.T.3
Harding, H.4
Ron, D.5
Marks, A.R.6
Tabas, I.7
-
40
-
-
33748961353
-
Mitochondrial membrane permeability transition and cell death
-
Tsujimoto Y., Nakagawa T., Shimizu S. Mitochondrial membrane permeability transition and cell death. Biochim. Biophys. Acta 2006, 1757:1297-1300.
-
(2006)
Biochim. Biophys. Acta
, vol.1757
, pp. 1297-1300
-
-
Tsujimoto, Y.1
Nakagawa, T.2
Shimizu, S.3
-
41
-
-
84870984470
-
PERK is required at the ER-mitochondrial contact sites to convey apoptosis after ROS-based ER stress
-
Verfaillie T., Rubio N., Garg A.D., Bultynck G., Rizzuto R., Decuypere J.P., Piette J., Linehan C., Gupta S., Samali A., Agostinis P. PERK is required at the ER-mitochondrial contact sites to convey apoptosis after ROS-based ER stress. Cell Death Differ. 2012, 19:1880-1891.
-
(2012)
Cell Death Differ.
, vol.19
, pp. 1880-1891
-
-
Verfaillie, T.1
Rubio, N.2
Garg, A.D.3
Bultynck, G.4
Rizzuto, R.5
Decuypere, J.P.6
Piette, J.7
Linehan, C.8
Gupta, S.9
Samali, A.10
Agostinis, P.11
-
42
-
-
28244466782
-
CHOP/GADD153 is a mediator of apoptotic death in substantia nigra dopamine neurons in an in vivo neurotoxin model of parkinsonism
-
Silva R.M., Ries V., Oo T.F., Yarygina O., Jackson-Lewis V., Ryu E.J., Lu P.D., Marciniak S.J., Ron D., Przedborski S., Kholodilov N., Greene L.A., Burke R.E. CHOP/GADD153 is a mediator of apoptotic death in substantia nigra dopamine neurons in an in vivo neurotoxin model of parkinsonism. J. Neurochem. 2005, 95:974-986.
-
(2005)
J. Neurochem.
, vol.95
, pp. 974-986
-
-
Silva, R.M.1
Ries, V.2
Oo, T.F.3
Yarygina, O.4
Jackson-Lewis, V.5
Ryu, E.J.6
Lu, P.D.7
Marciniak, S.J.8
Ron, D.9
Przedborski, S.10
Kholodilov, N.11
Greene, L.A.12
Burke, R.E.13
-
43
-
-
77957711395
-
The endoplasmic reticulum stress-C/EBP homologous protein pathway-mediated apoptosis in macrophages contributes to the instability of atherosclerotic plaques
-
Tsukano H., Gotoh T., Endo M., Miyata K., Tazume H., Kadomatsu T., Yano M., Iwawaki T., Kohno K., Araki K., Mizuta H., Oike Y. The endoplasmic reticulum stress-C/EBP homologous protein pathway-mediated apoptosis in macrophages contributes to the instability of atherosclerotic plaques. Arterioscler. Thromb. Vasc. Biol. 2010, 30:1925-1932.
-
(2010)
Arterioscler. Thromb. Vasc. Biol.
, vol.30
, pp. 1925-1932
-
-
Tsukano, H.1
Gotoh, T.2
Endo, M.3
Miyata, K.4
Tazume, H.5
Kadomatsu, T.6
Yano, M.7
Iwawaki, T.8
Kohno, K.9
Araki, K.10
Mizuta, H.11
Oike, Y.12
-
44
-
-
24144472287
-
Role of CHOP in hepatic apoptosis in the murine model of intragastric ethanol feeding
-
Ji C., Mehrian-Shai R., Chan C., Hsu Y.H., Kaplowitz N. Role of CHOP in hepatic apoptosis in the murine model of intragastric ethanol feeding. Alcohol. Clin. Exp. Res. 2005, 29:1496-1503.
-
(2005)
Alcohol. Clin. Exp. Res.
, vol.29
, pp. 1496-1503
-
-
Ji, C.1
Mehrian-Shai, R.2
Chan, C.3
Hsu, Y.H.4
Kaplowitz, N.5
-
45
-
-
36049049392
-
IRE1 signaling affects cell fate during the unfolded protein response
-
Lin J.H., Li H., Yasumura D., Cohen H.R., Zhang C., Panning B., Shokat K.M., Lavail M.M., Walter P. IRE1 signaling affects cell fate during the unfolded protein response. Science 2007, 318:944-949.
-
(2007)
Science
, vol.318
, pp. 944-949
-
-
Lin, J.H.1
Li, H.2
Yasumura, D.3
Cohen, H.R.4
Zhang, C.5
Panning, B.6
Shokat, K.M.7
Lavail, M.M.8
Walter, P.9
-
46
-
-
68049110633
-
IRE1alpha kinase activation modes control alternate endoribonuclease outputs to determine divergent cell fates
-
Han D., Lerner A.G., Vande Walle L., Upton J.P., Xu W., Hagen A., Backes B.J., Oakes S.A., Papa F.R. IRE1alpha kinase activation modes control alternate endoribonuclease outputs to determine divergent cell fates. Cell 2009, 138:562-575.
-
(2009)
Cell
, vol.138
, pp. 562-575
-
-
Han, D.1
Lerner, A.G.2
Vande Walle, L.3
Upton, J.P.4
Xu, W.5
Hagen, A.6
Backes, B.J.7
Oakes, S.A.8
Papa, F.R.9
-
47
-
-
0036606540
-
ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats
-
Nishitoh H., Matsuzawa A., Tobiume K., Saegusa K., Takeda K., Inoue K., Hori S., Kakizuka A., Ichijo H. ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats. Genes Dev. 2002, 16:1345-1355.
-
(2002)
Genes Dev.
, vol.16
, pp. 1345-1355
-
-
Nishitoh, H.1
Matsuzawa, A.2
Tobiume, K.3
Saegusa, K.4
Takeda, K.5
Inoue, K.6
Hori, S.7
Kakizuka, A.8
Ichijo, H.9
-
48
-
-
0034723235
-
Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1
-
Urano F., Wang X., Bertolotti A., Zhang Y., Chung P., Harding H.P., Ron D. Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1. Science 2000, 287:664-666.
-
(2000)
Science
, vol.287
, pp. 664-666
-
-
Urano, F.1
Wang, X.2
Bertolotti, A.3
Zhang, Y.4
Chung, P.5
Harding, H.P.6
Ron, D.7
-
49
-
-
80455173839
-
BAX inhibitor-1 regulates autophagy by controlling the IRE1alpha branch of the unfolded protein response
-
Castillo K., Rojas-Rivera D., Lisbona F., Caballero B., Nassif M., Court F.A., Schuck S., Ibar C., Walter P., Sierralta J., Glavic A., Hetz C. BAX inhibitor-1 regulates autophagy by controlling the IRE1alpha branch of the unfolded protein response. EMBO J. 2011, 30:4465-4478.
-
(2011)
EMBO J.
, vol.30
, pp. 4465-4478
-
-
Castillo, K.1
Rojas-Rivera, D.2
Lisbona, F.3
Caballero, B.4
Nassif, M.5
Court, F.A.6
Schuck, S.7
Ibar, C.8
Walter, P.9
Sierralta, J.10
Glavic, A.11
Hetz, C.12
-
50
-
-
33645815074
-
Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1alpha-mediated NF-kappaB activation and down-regulation of TRAF2 expression
-
Hu P., Han Z., Couvillon A.D., Kaufman R.J., Exton J.H. Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1alpha-mediated NF-kappaB activation and down-regulation of TRAF2 expression. Mol. Cell. Biol. 2006, 26:3071-3084.
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 3071-3084
-
-
Hu, P.1
Han, Z.2
Couvillon, A.D.3
Kaufman, R.J.4
Exton, J.H.5
-
51
-
-
68549092781
-
Regulated Ire1-dependent decay of messenger RNAs in mammalian cells
-
Hollien J., Lin J.H., Li H., Stevens N., Walter P., Weissman J.S. Regulated Ire1-dependent decay of messenger RNAs in mammalian cells. J. Cell Biol. 2009, 186:323-331.
-
(2009)
J. Cell Biol.
, vol.186
, pp. 323-331
-
-
Hollien, J.1
Lin, J.H.2
Li, H.3
Stevens, N.4
Walter, P.5
Weissman, J.S.6
-
52
-
-
33745893809
-
Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response
-
Hollien J., Weissman J.S. Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response. Science 2006, 313:104-107.
-
(2006)
Science
, vol.313
, pp. 104-107
-
-
Hollien, J.1
Weissman, J.S.2
-
53
-
-
80052668828
-
Peptides derived from the bifunctional kinase/RNase enzyme IRE1alpha modulate IRE1alpha activity and protect cells from endoplasmic reticulum stress
-
Bouchecareilh M., Higa A., Fribourg S., Moenner M., Chevet E. Peptides derived from the bifunctional kinase/RNase enzyme IRE1alpha modulate IRE1alpha activity and protect cells from endoplasmic reticulum stress. FASEB J. 2011, 25:3115-3129.
-
(2011)
FASEB J.
, vol.25
, pp. 3115-3129
-
-
Bouchecareilh, M.1
Higa, A.2
Fribourg, S.3
Moenner, M.4
Chevet, E.5
-
54
-
-
84859587957
-
The molecular basis for selective inhibition of unconventional mRNA splicing by an IRE1-binding small molecule
-
Cross B.C., Bond P.J., Sadowski P.G., Jha B.K., Zak J., Goodman J.M., Silverman R.H., Neubert T.A., Baxendale I.R., Ron D., Harding H.P. The molecular basis for selective inhibition of unconventional mRNA splicing by an IRE1-binding small molecule. Proc. Natl. Acad. Sci. U. S. A. 2012, 109:E869-E878.
-
(2012)
Proc. Natl. Acad. Sci. U. S. A.
, vol.109
-
-
Cross, B.C.1
Bond, P.J.2
Sadowski, P.G.3
Jha, B.K.4
Zak, J.5
Goodman, J.M.6
Silverman, R.H.7
Neubert, T.A.8
Baxendale, I.R.9
Ron, D.10
Harding, H.P.11
-
55
-
-
84868525253
-
IRE1alpha cleaves select microRNAs during ER stress to derepress translation of proapoptotic caspase-2
-
Upton J.P., Wang L., Han D., Wang E.S., Huskey N.E., Lim L., Truitt M., McManus M.T., Ruggero D., Goga A., Papa F.R., Oakes S.A. IRE1alpha cleaves select microRNAs during ER stress to derepress translation of proapoptotic caspase-2. Science 2012, 338:818-822.
-
(2012)
Science
, vol.338
, pp. 818-822
-
-
Upton, J.P.1
Wang, L.2
Han, D.3
Wang, E.S.4
Huskey, N.E.5
Lim, L.6
Truitt, M.7
McManus, M.T.8
Ruggero, D.9
Goga, A.10
Papa, F.R.11
Oakes, S.A.12
-
56
-
-
84864682160
-
IRE1alpha induces thioredoxin-interacting protein to activate the NLRP3 inflammasome and promote programmed cell death under irremediable ER stress
-
Lerner A.G., Upton J.P., Praveen P.V., Ghosh R., Nakagawa Y., Igbaria A., Shen S., Nguyen V., Backes B.J., Heiman M., Heintz N., Greengard P., Hui S., Tang Q., Trusina A., Oakes S.A., Papa F.R. IRE1alpha induces thioredoxin-interacting protein to activate the NLRP3 inflammasome and promote programmed cell death under irremediable ER stress. Cell Metab. 2012, 16:250-264.
-
(2012)
Cell Metab.
, vol.16
, pp. 250-264
-
-
Lerner, A.G.1
Upton, J.P.2
Praveen, P.V.3
Ghosh, R.4
Nakagawa, Y.5
Igbaria, A.6
Shen, S.7
Nguyen, V.8
Backes, B.J.9
Heiman, M.10
Heintz, N.11
Greengard, P.12
Hui, S.13
Tang, Q.14
Trusina, A.15
Oakes, S.A.16
Papa, F.R.17
-
57
-
-
69749123786
-
Fine-tuning of the unfolded protein response: assembling the IRE1alpha interactome
-
Hetz C., Glimcher L.H. Fine-tuning of the unfolded protein response: assembling the IRE1alpha interactome. Mol. Cell 2009, 35:551-561.
-
(2009)
Mol. Cell
, vol.35
, pp. 551-561
-
-
Hetz, C.1
Glimcher, L.H.2
-
58
-
-
80054722420
-
The unfolded protein response: integrating stress signals through the stress sensor IRE1alpha
-
Hetz C., Martinon F., Rodriguez D., Glimcher L.H. The unfolded protein response: integrating stress signals through the stress sensor IRE1alpha. Physiol. Rev. 2011, 91:1219-1243.
-
(2011)
Physiol. Rev.
, vol.91
, pp. 1219-1243
-
-
Hetz, C.1
Martinon, F.2
Rodriguez, D.3
Glimcher, L.H.4
-
59
-
-
37549048249
-
The BCL-2 protein family: opposing activities that mediate cell death
-
Youle R.J., Strasser A. The BCL-2 protein family: opposing activities that mediate cell death. Nat. Rev. Mol. Cell Biol. 2008, 9:47-59.
-
(2008)
Nat. Rev. Mol. Cell Biol.
, vol.9
, pp. 47-59
-
-
Youle, R.J.1
Strasser, A.2
-
60
-
-
0036716281
-
The Bcl2 family: regulators of the cellular life-or-death switch
-
Cory S., Adams J.M. The Bcl2 family: regulators of the cellular life-or-death switch. Nat. Rev. Cancer 2002, 2:647-656.
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 647-656
-
-
Cory, S.1
Adams, J.M.2
-
61
-
-
68149147330
-
BNIP3 subfamily BH3-only proteins: mitochondrial stress sensors in normal and pathological functions
-
Chinnadurai G., Vijayalingam S., Gibson S.B. BNIP3 subfamily BH3-only proteins: mitochondrial stress sensors in normal and pathological functions. Oncogene 2008, 27(Suppl. 1):S114-S127.
-
(2008)
Oncogene
, vol.27
, Issue.SUPPL. 1
-
-
Chinnadurai, G.1
Vijayalingam, S.2
Gibson, S.B.3
-
62
-
-
0037898897
-
BNips: a group of pro-apoptotic proteins in the Bcl-2 family
-
Zhang H.M., Cheung P., Yanagawa B., McManus B.M., Yang D.C. BNips: a group of pro-apoptotic proteins in the Bcl-2 family. Apoptosis 2003, 8:229-236.
-
(2003)
Apoptosis
, vol.8
, pp. 229-236
-
-
Zhang, H.M.1
Cheung, P.2
Yanagawa, B.3
McManus, B.M.4
Yang, D.C.5
-
63
-
-
77956095537
-
Mitochondria and cell death: outer membrane permeabilization and beyond
-
Tait S.W., Green D.R. Mitochondria and cell death: outer membrane permeabilization and beyond. Nat. Rev. Mol. Cell Biol. 2010, 11:621-632.
-
(2010)
Nat. Rev. Mol. Cell Biol.
, vol.11
, pp. 621-632
-
-
Tait, S.W.1
Green, D.R.2
-
64
-
-
0036728834
-
Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics
-
Letai A., Bassik M.C., Walensky L.D., Sorcinelli M.D., Weiler S., Korsmeyer S.J. Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics. Cancer Cell 2002, 2:183-192.
-
(2002)
Cancer Cell
, vol.2
, pp. 183-192
-
-
Letai, A.1
Bassik, M.C.2
Walensky, L.D.3
Sorcinelli, M.D.4
Weiler, S.5
Korsmeyer, S.J.6
-
65
-
-
37849026130
-
The daily job of night killers: alternative roles of the BCL-2 family in organelle physiology
-
Hetz C., Glimcher L. The daily job of night killers: alternative roles of the BCL-2 family in organelle physiology. Trends Cell Biol. 2008, 18:38-44.
-
(2008)
Trends Cell Biol.
, vol.18
, pp. 38-44
-
-
Hetz, C.1
Glimcher, L.2
-
66
-
-
35848969791
-
ER stress signaling and the BCL-2 family of proteins: from adaptation to irreversible cellular damage
-
Hetz C.A. ER stress signaling and the BCL-2 family of proteins: from adaptation to irreversible cellular damage. Antioxid. Redox Signal. 2007, 9:2345-2355.
-
(2007)
Antioxid. Redox Signal.
, vol.9
, pp. 2345-2355
-
-
Hetz, C.A.1
-
67
-
-
66149128392
-
Bcl-2 family on guard at the ER
-
Szegezdi E., Macdonald D.C., Ni Chonghaile T., Gupta S., Samali A. Bcl-2 family on guard at the ER. Am. J. Physiol. Cell Physiol. 2009, 296:C941-C953.
-
(2009)
Am. J. Physiol. Cell Physiol.
, vol.296
-
-
Szegezdi, E.1
Macdonald, D.C.2
Ni Chonghaile, T.3
Gupta, S.4
Samali, A.5
-
68
-
-
69249139451
-
Human melanoma cells under endoplasmic reticulum stress are more susceptible to apoptosis induced by the BH3 mimetic obatoclax
-
Jiang C.C., Wroblewski D., Yang F., Hersey P., Zhang X.D. Human melanoma cells under endoplasmic reticulum stress are more susceptible to apoptosis induced by the BH3 mimetic obatoclax. Neoplasia 2009, 11:945-955.
-
(2009)
Neoplasia
, vol.11
, pp. 945-955
-
-
Jiang, C.C.1
Wroblewski, D.2
Yang, F.3
Hersey, P.4
Zhang, X.D.5
-
69
-
-
33646237823
-
Proapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1alpha
-
Hetz C., Bernasconi P., Fisher J., Lee A.H., Bassik M.C., Antonsson B., Brandt G.S., Iwakoshi N.N., Schinzel A., Glimcher L.H., Korsmeyer S.J. Proapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1alpha. Science 2006, 312:572-576.
-
(2006)
Science
, vol.312
, pp. 572-576
-
-
Hetz, C.1
Bernasconi, P.2
Fisher, J.3
Lee, A.H.4
Bassik, M.C.5
Antonsson, B.6
Brandt, G.S.7
Iwakoshi, N.N.8
Schinzel, A.9
Glimcher, L.H.10
Korsmeyer, S.J.11
-
70
-
-
84861188701
-
BH3-only proteins are part of a regulatory network that control the sustained signalling of the unfolded protein response sensor IRE1alpha
-
Rodriguez D.A., Zamorano S., Lisbona F., Rojas-Rivera D., Urra H., Cubillos-Ruiz J.R., Armisen R., Henriquez D.R., Cheng E.H., Letek M., Vaisar T., Irrazabal T., Gonzalez-Billault C., Letai A., Pimentel-Muinos F.X., Kroemer G., Hetz C. BH3-only proteins are part of a regulatory network that control the sustained signalling of the unfolded protein response sensor IRE1alpha. EMBO J. 2012, 31:2322-2335.
-
(2012)
EMBO J.
, vol.31
, pp. 2322-2335
-
-
Rodriguez, D.A.1
Zamorano, S.2
Lisbona, F.3
Rojas-Rivera, D.4
Urra, H.5
Cubillos-Ruiz, J.R.6
Armisen, R.7
Henriquez, D.R.8
Cheng, E.H.9
Letek, M.10
Vaisar, T.11
Irrazabal, T.12
Gonzalez-Billault, C.13
Letai, A.14
Pimentel-Muinos, F.X.15
Kroemer, G.16
Hetz, C.17
-
71
-
-
80052074729
-
Ets-1 mediates upregulation of Mcl-1 downstream of XBP-1 in human melanoma cells upon ER stress
-
Dong L., Jiang C.C., Thorne R.F., Croft A., Yang F., Liu H., de Bock C.E., Hersey P., Zhang X.D. Ets-1 mediates upregulation of Mcl-1 downstream of XBP-1 in human melanoma cells upon ER stress. Oncogene 2011, 30:3716-3726.
-
(2011)
Oncogene
, vol.30
, pp. 3716-3726
-
-
Dong, L.1
Jiang, C.C.2
Thorne, R.F.3
Croft, A.4
Yang, F.5
Liu, H.6
de Bock, C.E.7
Hersey, P.8
Zhang, X.D.9
-
72
-
-
53049105459
-
Up-regulation of Mcl-1 is critical for survival of human melanoma cells upon endoplasmic reticulum stress
-
Jiang C.C., Lucas K., Avery-Kiejda K.A., Wade M., deBock C.E., Thorne R.F., Allen J., Hersey P., Zhang X.D. Up-regulation of Mcl-1 is critical for survival of human melanoma cells upon endoplasmic reticulum stress. Cancer Res. 2008, 68:6708-6717.
-
(2008)
Cancer Res.
, vol.68
, pp. 6708-6717
-
-
Jiang, C.C.1
Lucas, K.2
Avery-Kiejda, K.A.3
Wade, M.4
deBock, C.E.5
Thorne, R.F.6
Allen, J.7
Hersey, P.8
Zhang, X.D.9
-
73
-
-
84869050209
-
A novel cellular stress response characterised by a rapid reorganisation of membranes of the endoplasmic reticulum
-
Varadarajan S., Bampton E.T., Smalley J.L., Tanaka K., Caves R.E., Butterworth M., Wei J., Pellecchia M., Mitcheson J., Gant T.W., Dinsdale D., Cohen G.M. A novel cellular stress response characterised by a rapid reorganisation of membranes of the endoplasmic reticulum. Cell Death Differ. 2012, 19:1896-1907.
-
(2012)
Cell Death Differ.
, vol.19
, pp. 1896-1907
-
-
Varadarajan, S.1
Bampton, E.T.2
Smalley, J.L.3
Tanaka, K.4
Caves, R.E.5
Butterworth, M.6
Wei, J.7
Pellecchia, M.8
Mitcheson, J.9
Gant, T.W.10
Dinsdale, D.11
Cohen, G.M.12
-
74
-
-
84862996844
-
CHOP potentially co-operates with FOXO3a in neuronal cells to regulate PUMA and BIM expression in response to ER stress
-
Ghosh A.P., Klocke B.J., Ballestas M.E., Roth K.A. CHOP potentially co-operates with FOXO3a in neuronal cells to regulate PUMA and BIM expression in response to ER stress. PLoS One 2012, 7:e39586.
-
(2012)
PLoS One
, vol.7
-
-
Ghosh, A.P.1
Klocke, B.J.2
Ballestas, M.E.3
Roth, K.A.4
-
75
-
-
9644295726
-
Translocation of Bim to the endoplasmic reticulum (ER) mediates ER stress signaling for activation of caspase-12 during ER stress-induced apoptosis
-
Morishima N., Nakanishi K., Tsuchiya K., Shibata T., Seiwa E. Translocation of Bim to the endoplasmic reticulum (ER) mediates ER stress signaling for activation of caspase-12 during ER stress-induced apoptosis. J. Biol. Chem. 2004, 279:50375-50381.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 50375-50381
-
-
Morishima, N.1
Nakanishi, K.2
Tsuchiya, K.3
Shibata, T.4
Seiwa, E.5
-
76
-
-
33646373219
-
Endoplasmic reticulum stress-induced apoptosis: multiple pathways and activation of p53-up-regulated modulator of apoptosis (PUMA) and NOXA by p53
-
Li J., Lee B., Lee A.S. Endoplasmic reticulum stress-induced apoptosis: multiple pathways and activation of p53-up-regulated modulator of apoptosis (PUMA) and NOXA by p53. J. Biol. Chem. 2006, 281:7260-7270.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 7260-7270
-
-
Li, J.1
Lee, B.2
Lee, A.S.3
-
77
-
-
77949911706
-
Regulation of endoplasmic reticulum stress-induced cell death by ATF4 in neuroectodermal tumor cells
-
Armstrong J.L., Flockhart R., Veal G.J., Lovat P.E., Redfern C.P. Regulation of endoplasmic reticulum stress-induced cell death by ATF4 in neuroectodermal tumor cells. J. Biol. Chem. 2010, 285:6091-6100.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 6091-6100
-
-
Armstrong, J.L.1
Flockhart, R.2
Veal, G.J.3
Lovat, P.E.4
Redfern, C.P.5
-
78
-
-
12244288323
-
BAD and Bcl-2 regulation are early events linking neuronal endoplasmic reticulum stress to mitochondria-mediated apoptosis
-
Elyaman W., Terro F., Suen K.C., Yardin C., Chang R.C., Hugon J. BAD and Bcl-2 regulation are early events linking neuronal endoplasmic reticulum stress to mitochondria-mediated apoptosis. Brain Res. Mol. Brain Res. 2002, 109:233-238.
-
(2002)
Brain Res. Mol. Brain Res.
, vol.109
, pp. 233-238
-
-
Elyaman, W.1
Terro, F.2
Suen, K.C.3
Yardin, C.4
Chang, R.C.5
Hugon, J.6
-
79
-
-
77955930962
-
Mechanisms of ER stress-mediated mitochondrial membrane permeabilization
-
Gupta S., Cuffe L., Szegezdi E., Logue S.E., Neary C., Healy S., Samali A. Mechanisms of ER stress-mediated mitochondrial membrane permeabilization. Int. J. Cell Biol. 2010, 2010:170215.
-
(2010)
Int. J. Cell Biol.
, vol.2010
, pp. 170215
-
-
Gupta, S.1
Cuffe, L.2
Szegezdi, E.3
Logue, S.E.4
Neary, C.5
Healy, S.6
Samali, A.7
-
80
-
-
44949233264
-
Caspase-2 cleavage of BID is a critical apoptotic signal downstream of endoplasmic reticulum stress
-
Upton J.P., Austgen K., Nishino M., Coakley K.M., Hagen A., Han D., Papa F.R., Oakes S.A. Caspase-2 cleavage of BID is a critical apoptotic signal downstream of endoplasmic reticulum stress. Mol. Cell. Biol. 2008, 28:3943-3951.
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 3943-3951
-
-
Upton, J.P.1
Austgen, K.2
Nishino, M.3
Coakley, K.M.4
Hagen, A.5
Han, D.6
Papa, F.R.7
Oakes, S.A.8
-
81
-
-
84869012711
-
The ER in 4D: a novel stress pathway controlling endoplasmic reticulum membrane remodeling
-
Urra H., Hetz C. The ER in 4D: a novel stress pathway controlling endoplasmic reticulum membrane remodeling. Cell Death Differ. 2012, 19:1893-1895.
-
(2012)
Cell Death Differ.
, vol.19
, pp. 1893-1895
-
-
Urra, H.1
Hetz, C.2
-
82
-
-
14744281338
-
L specifically activates Bak to induce swelling and restructuring of the endoplasmic reticulum
-
L specifically activates Bak to induce swelling and restructuring of the endoplasmic reticulum. J. Cell Biol. 2005, 168:723-734.
-
(2005)
J. Cell Biol.
, vol.168
, pp. 723-734
-
-
Klee, M.1
Pimentel-Muinos, F.X.2
-
83
-
-
84877579142
-
Intracellular localization of the BCL-2 family member BOK and functional implications
-
Echeverry N., Bachmann D., Ke F., Strasser A., Simon H.U., Kaufmann T. Intracellular localization of the BCL-2 family member BOK and functional implications. Cell Death Differ. 2013, 20:785-799.
-
(2013)
Cell Death Differ.
, vol.20
, pp. 785-799
-
-
Echeverry, N.1
Bachmann, D.2
Ke, F.3
Strasser, A.4
Simon, H.U.5
Kaufmann, T.6
-
84
-
-
4444304199
-
Involvement of BNIP1 in apoptosis and endoplasmic reticulum membrane fusion
-
Nakajima K., Hirose H., Taniguchi M., Kurashina H., Arasaki K., Nagahama M., Tani K., Yamamoto A., Tagaya M. Involvement of BNIP1 in apoptosis and endoplasmic reticulum membrane fusion. EMBO J. 2004, 23:3216-3226.
-
(2004)
EMBO J.
, vol.23
, pp. 3216-3226
-
-
Nakajima, K.1
Hirose, H.2
Taniguchi, M.3
Kurashina, H.4
Arasaki, K.5
Nagahama, M.6
Tani, K.7
Yamamoto, A.8
Tagaya, M.9
-
85
-
-
84860431569
-
Endoplasmic reticulum-specific BH3-only protein BNIP1 induces mitochondrial fragmentation in a Bcl-2- and Drp1-dependent manner
-
Ryu S.W., Choi K., Yoon J., Kim S., Choi C. Endoplasmic reticulum-specific BH3-only protein BNIP1 induces mitochondrial fragmentation in a Bcl-2- and Drp1-dependent manner. J. Cell. Physiol. 2012, 227:3027-3035.
-
(2012)
J. Cell. Physiol.
, vol.227
, pp. 3027-3035
-
-
Ryu, S.W.1
Choi, K.2
Yoon, J.3
Kim, S.4
Choi, C.5
-
86
-
-
84857874320
-
JNK modulates FOXO3a for the expression of the mitochondrial death and mitophagy marker BNIP3 in pathological hypertrophy and in heart failure
-
Chaanine A.H., Jeong D., Liang L., Chemaly E.R., Fish K., Gordon R.E., Hajjar R.J. JNK modulates FOXO3a for the expression of the mitochondrial death and mitophagy marker BNIP3 in pathological hypertrophy and in heart failure. Cell Death Dis. 2012, 3:265.
-
(2012)
Cell Death Dis.
, vol.3
, pp. 265
-
-
Chaanine, A.H.1
Jeong, D.2
Liang, L.3
Chemaly, E.R.4
Fish, K.5
Gordon, R.E.6
Hajjar, R.J.7
-
87
-
-
84879240043
-
Potential role of BNIP3 in cardiac remodeling, myocardial stiffness and endoplasmic reticulum-mitochondrial calcium homeostasis in diastolic and systolic heart failure
-
Chaanine A.H., Gordon R.E., Kohlbrenner E., Benard L., Jeong D., Hajjar R.J. Potential role of BNIP3 in cardiac remodeling, myocardial stiffness and endoplasmic reticulum-mitochondrial calcium homeostasis in diastolic and systolic heart failure. Circ. Heart Fail. 2013, 6:572-583.
-
(2013)
Circ. Heart Fail.
, vol.6
, pp. 572-583
-
-
Chaanine, A.H.1
Gordon, R.E.2
Kohlbrenner, E.3
Benard, L.4
Jeong, D.5
Hajjar, R.J.6
-
89
-
-
84859867839
-
Bim links ER stress and apoptosis in cells expressing mutant SOD1 associated with amyotrophic lateral sclerosis
-
Soo K.Y., Atkin J.D., Farg M., Walker A.K., Horne M.K., Nagley P. Bim links ER stress and apoptosis in cells expressing mutant SOD1 associated with amyotrophic lateral sclerosis. PLoS One 2012, 7:e35413.
-
(2012)
PLoS One
, vol.7
-
-
Soo, K.Y.1
Atkin, J.D.2
Farg, M.3
Walker, A.K.4
Horne, M.K.5
Nagley, P.6
-
90
-
-
79953855830
-
TDP-43-induced death is associated with altered regulation of BIM and Bcl-xL and attenuated by caspase-mediated TDP-43 cleavage
-
Suzuki H., Lee K., Matsuoka M. TDP-43-induced death is associated with altered regulation of BIM and Bcl-xL and attenuated by caspase-mediated TDP-43 cleavage. J. Biol. Chem. 2011, 286:13171-13183.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 13171-13183
-
-
Suzuki, H.1
Lee, K.2
Matsuoka, M.3
-
91
-
-
77953213749
-
BimEL as a possible molecular link between proteasome dysfunction and cell death induced by mutant huntingtin
-
Leon R., Bhagavatula N., Ulukpo O., McCollum M., Wei J. BimEL as a possible molecular link between proteasome dysfunction and cell death induced by mutant huntingtin. Eur. J. Neurosci. 2010, 31:1915-1925.
-
(2010)
Eur. J. Neurosci.
, vol.31
, pp. 1915-1925
-
-
Leon, R.1
Bhagavatula, N.2
Ulukpo, O.3
McCollum, M.4
Wei, J.5
-
92
-
-
78650412221
-
Neuronal apoptosis induced by endoplasmic reticulum stress is regulated by ATF4-CHOP-mediated induction of the Bcl-2 homology 3-only member PUMA
-
Galehdar Z., Swan P., Fuerth B., Callaghan S.M., Park D.S., Cregan S.P. Neuronal apoptosis induced by endoplasmic reticulum stress is regulated by ATF4-CHOP-mediated induction of the Bcl-2 homology 3-only member PUMA. J. Neurosci. 2010, 30:16938-16948.
-
(2010)
J. Neurosci.
, vol.30
, pp. 16938-16948
-
-
Galehdar, Z.1
Swan, P.2
Fuerth, B.3
Callaghan, S.M.4
Park, D.S.5
Cregan, S.P.6
-
93
-
-
38049097948
-
Deletion of the BH3-only protein puma protects motoneurons from ER stress-induced apoptosis and delays motoneuron loss in ALS mice
-
Kieran D., Woods I., Villunger A., Strasser A., Prehn J.H. Deletion of the BH3-only protein puma protects motoneurons from ER stress-induced apoptosis and delays motoneuron loss in ALS mice. Proc. Natl. Acad. Sci. U. S. A. 2007, 104:20606-20611.
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 20606-20611
-
-
Kieran, D.1
Woods, I.2
Villunger, A.3
Strasser, A.4
Prehn, J.H.5
-
94
-
-
33845567527
-
PUMA is critical for neonatal cardiomyocyte apoptosis induced by endoplasmic reticulum stress
-
Nickson P., Toth A., Erhardt P. PUMA is critical for neonatal cardiomyocyte apoptosis induced by endoplasmic reticulum stress. Cardiovasc. Res. 2007, 73:48-56.
-
(2007)
Cardiovasc. Res.
, vol.73
, pp. 48-56
-
-
Nickson, P.1
Toth, A.2
Erhardt, P.3
-
95
-
-
84878359009
-
Regulation of inositol 1,4,5-trisphosphate receptors during endoplasmic reticulum stress
-
Kiviluoto S., Vervliet T., Ivanova H., Decuypere J.P., De Smedt H., Missiaen L., Bultynck G., Parys J.B. Regulation of inositol 1,4,5-trisphosphate receptors during endoplasmic reticulum stress. Biochim. Biophys. Acta 2013.
-
(2013)
Biochim. Biophys. Acta
-
-
Kiviluoto, S.1
Vervliet, T.2
Ivanova, H.3
Decuypere, J.P.4
De Smedt, H.5
Missiaen, L.6
Bultynck, G.7
Parys, J.B.8
-
97
-
-
77149136381
-
Calcium binding chaperones of the endoplasmic reticulum
-
(Spec No Focus)
-
Coe H., Michalak M. Calcium binding chaperones of the endoplasmic reticulum. Gen. Physiol. Biophys. 2009, 28:F96-F103. (Spec No Focus).
-
(2009)
Gen. Physiol. Biophys.
, vol.28
-
-
Coe, H.1
Michalak, M.2
-
98
-
-
84860774401
-
TMBIM3/GRINA is a novel unfolded protein response (UPR) target gene that controls apoptosis through the modulation of ER calcium homeostasis
-
Rojas-Rivera D., Armisen R., Colombo A., Martinez G., Eguiguren A.L., Diaz A., Kiviluoto S., Rodriguez D., Patron M., Rizzuto R., Bultynck G., Concha M.L., Sierralta J., Stutzin A., Hetz C. TMBIM3/GRINA is a novel unfolded protein response (UPR) target gene that controls apoptosis through the modulation of ER calcium homeostasis. Cell Death Differ. 2012, 19:1013-1026.
-
(2012)
Cell Death Differ.
, vol.19
, pp. 1013-1026
-
-
Rojas-Rivera, D.1
Armisen, R.2
Colombo, A.3
Martinez, G.4
Eguiguren, A.L.5
Diaz, A.6
Kiviluoto, S.7
Rodriguez, D.8
Patron, M.9
Rizzuto, R.10
Bultynck, G.11
Concha, M.L.12
Sierralta, J.13
Stutzin, A.14
Hetz, C.15
-
99
-
-
11844284861
-
Proapoptotic BAX and BAK regulate the type 1 inositol trisphosphate receptor and calcium leak from the endoplasmic reticulum
-
Oakes S.A., Scorrano L., Opferman J.T., Bassik M.C., Nishino M., Pozzan T., Korsmeyer S.J. Proapoptotic BAX and BAK regulate the type 1 inositol trisphosphate receptor and calcium leak from the endoplasmic reticulum. Proc. Natl. Acad. Sci. U. S. A. 2005, 102:105-110.
-
(2005)
Proc. Natl. Acad. Sci. U. S. A.
, vol.102
, pp. 105-110
-
-
Oakes, S.A.1
Scorrano, L.2
Opferman, J.T.3
Bassik, M.C.4
Nishino, M.5
Pozzan, T.6
Korsmeyer, S.J.7
-
100
-
-
84875608277
-
Modulation of ER stress and apoptosis by endoplasmic reticulum calcium leak via translocon during unfolded protein response: involvement of GRP78
-
Hammadi M., Oulidi A., Gackiere F., Katsogiannou M., Slomianny C., Roudbaraki M., Dewailly E., Delcourt P., Lepage G., Lotteau S., Ducreux S., Prevarskaya N., Van Coppenolle F. Modulation of ER stress and apoptosis by endoplasmic reticulum calcium leak via translocon during unfolded protein response: involvement of GRP78. FASEB J. 2013, 27:1600-1609.
-
(2013)
FASEB J.
, vol.27
, pp. 1600-1609
-
-
Hammadi, M.1
Oulidi, A.2
Gackiere, F.3
Katsogiannou, M.4
Slomianny, C.5
Roudbaraki, M.6
Dewailly, E.7
Delcourt, P.8
Lepage, G.9
Lotteau, S.10
Ducreux, S.11
Prevarskaya, N.12
Van Coppenolle, F.13
-
101
-
-
38049155818
-
Endoplasmic reticulum stress induces calcium-dependent permeability transition, mitochondrial outer membrane permeabilization and apoptosis
-
Deniaud A., Sharaf el dein O., Maillier E., Poncet D., Kroemer G., Lemaire C., Brenner C. Endoplasmic reticulum stress induces calcium-dependent permeability transition, mitochondrial outer membrane permeabilization and apoptosis. Oncogene 2008, 27:285-299.
-
(2008)
Oncogene
, vol.27
, pp. 285-299
-
-
Deniaud, A.1
Sharaf El Dein, O.2
Maillier, E.3
Poncet, D.4
Kroemer, G.5
Lemaire, C.6
Brenner, C.7
-
102
-
-
0037418843
-
2+: a control point for apoptosis
-
2+: a control point for apoptosis. Science 2003, 300:135-139.
-
(2003)
Science
, vol.300
, pp. 135-139
-
-
Scorrano, L.1
Oakes, S.A.2
Opferman, J.T.3
Cheng, E.H.4
Sorcinelli, M.D.5
Pozzan, T.6
Korsmeyer, S.J.7
-
103
-
-
83555176031
-
Endoplasmic reticulum: ER stress regulates mitochondrial bioenergetics
-
Bravo R., Gutierrez T., Paredes F., Gatica D., Rodriguez A.E., Pedrozo Z., Chiong M., Parra V., Quest A.F., Rothermel B.A., Lavandero S. Endoplasmic reticulum: ER stress regulates mitochondrial bioenergetics. Int. J. Biochem. Cell Biol. 2012, 44:16-20.
-
(2012)
Int. J. Biochem. Cell Biol.
, vol.44
, pp. 16-20
-
-
Bravo, R.1
Gutierrez, T.2
Paredes, F.3
Gatica, D.4
Rodriguez, A.E.5
Pedrozo, Z.6
Chiong, M.7
Parra, V.8
Quest, A.F.9
Rothermel, B.A.10
Lavandero, S.11
-
104
-
-
79960310339
-
Increased ER-mitochondrial coupling promotes mitochondrial respiration and bioenergetics during early phases of ER stress
-
Bravo R., Vicencio J.M., Parra V., Troncoso R., Munoz J.P., Bui M., Quiroga C., Rodriguez A.E., Verdejo H.E., Ferreira J., Iglewski M., Chiong M., Simmen T., Zorzano A., Hill J.A., Rothermel B.A., Szabadkai G., Lavandero S. Increased ER-mitochondrial coupling promotes mitochondrial respiration and bioenergetics during early phases of ER stress. J. Cell Sci. 2011, 124:2143-2152.
-
(2011)
J. Cell Sci.
, vol.124
, pp. 2143-2152
-
-
Bravo, R.1
Vicencio, J.M.2
Parra, V.3
Troncoso, R.4
Munoz, J.P.5
Bui, M.6
Quiroga, C.7
Rodriguez, A.E.8
Verdejo, H.E.9
Ferreira, J.10
Iglewski, M.11
Chiong, M.12
Simmen, T.13
Zorzano, A.14
Hill, J.A.15
Rothermel, B.A.16
Szabadkai, G.17
Lavandero, S.18
-
109
-
-
0034610995
-
2+ influx in Bcl-2-overexpressing cells
-
2+ influx in Bcl-2-overexpressing cells. J. Cell Biol. 2000, 148:857-862.
-
(2000)
J. Cell Biol.
, vol.148
, pp. 857-862
-
-
Pinton, P.1
Ferrari, D.2
Magalhaes, P.3
Schulze-Osthoff, K.4
Di Virgilio, F.5
Pozzan, T.6
Rizzuto, R.7
-
110
-
-
0034705141
-
2+ concentration within the endoplasmic reticulum
-
2+ concentration within the endoplasmic reticulum. Proc. Natl. Acad. Sci. U. S. A. 2000, 97:5723-5728.
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 5723-5728
-
-
Foyouzi-Youssefi, R.1
Arnaudeau, S.2
Borner, C.3
Kelley, W.L.4
Tschopp, J.5
Lew, D.P.6
Demaurex, N.7
Krause, K.H.8
-
111
-
-
0035355341
-
2+ concentration of the endoplasmic reticulum is a key determinant of ceramide-induced apoptosis: significance for the molecular mechanism of Bcl-2 action
-
2+ concentration of the endoplasmic reticulum is a key determinant of ceramide-induced apoptosis: significance for the molecular mechanism of Bcl-2 action. EMBO J. 2001, 20:2690-2701.
-
(2001)
EMBO J.
, vol.20
, pp. 2690-2701
-
-
Pinton, P.1
Ferrari, D.2
Rapizzi, E.3
Di Virgilio, F.4
Pozzan, T.5
Rizzuto, R.6
-
112
-
-
33646183455
-
The control of endoplasmic reticulum-initiated apoptosis by the BCL-2 family of proteins
-
Oakes S.A., Lin S.S., Bassik M.C. The control of endoplasmic reticulum-initiated apoptosis by the BCL-2 family of proteins. Curr. Mol. Med. 2006, 6:99-109.
-
(2006)
Curr. Mol. Med.
, vol.6
, pp. 99-109
-
-
Oakes, S.A.1
Lin, S.S.2
Bassik, M.C.3
-
113
-
-
68649115556
-
2+ transfer from the ER to mitochondria: when, how and why
-
2+ transfer from the ER to mitochondria: when, how and why. Biochim. Biophys. Acta 2009, 1787:1342-1351.
-
(2009)
Biochim. Biophys. Acta
, vol.1787
, pp. 1342-1351
-
-
Rizzuto, R.1
Marchi, S.2
Bonora, M.3
Aguiari, P.4
Bononi, A.5
De Stefani, D.6
Giorgi, C.7
Leo, S.8
Rimessi, A.9
Siviero, R.10
Zecchini, E.11
Pinton, P.12
-
114
-
-
0037810844
-
Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis
-
Zong W.X., Li C., Hatzivassiliou G., Lindsten T., Yu Q.C., Yuan J., Thompson C.B. Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis. J. Cell Biol. 2003, 162:59-69.
-
(2003)
J. Cell Biol.
, vol.162
, pp. 59-69
-
-
Zong, W.X.1
Li, C.2
Hatzivassiliou, G.3
Lindsten, T.4
Yu, Q.C.5
Yuan, J.6
Thompson, C.B.7
-
115
-
-
3342984659
-
Bcl-2 functionally interacts with inositol 1,4,5-trisphosphate receptors to regulate calcium release from the ER in response to inositol 1,4,5-trisphosphate
-
Chen R., Valencia I., Zhong F., McColl K.S., Roderick H.L., Bootman M.D., Berridge M.J., Conway S.J., Holmes A.B., Mignery G.A., Velez P., Distelhorst C.W. Bcl-2 functionally interacts with inositol 1,4,5-trisphosphate receptors to regulate calcium release from the ER in response to inositol 1,4,5-trisphosphate. J. Cell Biol. 2004, 166:193-203.
-
(2004)
J. Cell Biol.
, vol.166
, pp. 193-203
-
-
Chen, R.1
Valencia, I.2
Zhong, F.3
McColl, K.S.4
Roderick, H.L.5
Bootman, M.D.6
Berridge, M.J.7
Conway, S.J.8
Holmes, A.B.9
Mignery, G.A.10
Velez, P.11
Distelhorst, C.W.12
-
116
-
-
27144487808
-
L modulation of the InsP3R
-
L modulation of the InsP3R. Nat. Cell Biol. 2005, 7:1021-1028.
-
(2005)
Nat. Cell Biol.
, vol.7
, pp. 1021-1028
-
-
White, C.1
Li, C.2
Yang, J.3
Petrenko, N.B.4
Madesh, M.5
Thompson, C.B.6
Foskett, J.K.7
-
118
-
-
84862209309
-
A BAX/BAK and cyclophilin D-independent intrinsic apoptosis pathway
-
Zamorano S., Rojas-Rivera D., Lisbona F., Parra V., Court F.A., Villegas R., Cheng E.H., Korsmeyer S.J., Lavandero S., Hetz C. A BAX/BAK and cyclophilin D-independent intrinsic apoptosis pathway. PLoS One 2012, 7:e37782.
-
(2012)
PLoS One
, vol.7
-
-
Zamorano, S.1
Rojas-Rivera, D.2
Lisbona, F.3
Parra, V.4
Court, F.A.5
Villegas, R.6
Cheng, E.H.7
Korsmeyer, S.J.8
Lavandero, S.9
Hetz, C.10
-
119
-
-
24744460273
-
Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia
-
Schinzel A.C., Takeuchi O., Huang Z., Fisher J.K., Zhou Z., Rubens J., Hetz C., Danial N.N., Moskowitz M.A., Korsmeyer S.J. Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia. Proc. Natl. Acad. Sci. U. S. A. 2005, 102:12005-12010.
-
(2005)
Proc. Natl. Acad. Sci. U. S. A.
, vol.102
, pp. 12005-12010
-
-
Schinzel, A.C.1
Takeuchi, O.2
Huang, Z.3
Fisher, J.K.4
Zhou, Z.5
Rubens, J.6
Hetz, C.7
Danial, N.N.8
Moskowitz, M.A.9
Korsmeyer, S.J.10
-
120
-
-
8444220527
-
Molecular mechanisms of caspase regulation during apoptosis
-
Riedl S.J., Shi Y. Molecular mechanisms of caspase regulation during apoptosis. Nat. Rev. Mol. Cell Biol. 2004, 5:897-907.
-
(2004)
Nat. Rev. Mol. Cell Biol.
, vol.5
, pp. 897-907
-
-
Riedl, S.J.1
Shi, Y.2
-
121
-
-
0034610743
-
Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta
-
Nakagawa T., Zhu H., Morishima N., Li E., Xu J., Yankner B.A., Yuan J. Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta. Nature 2000, 403:98-103.
-
(2000)
Nature
, vol.403
, pp. 98-103
-
-
Nakagawa, T.1
Zhu, H.2
Morishima, N.3
Li, E.4
Xu, J.5
Yankner, B.A.6
Yuan, J.7
-
122
-
-
2442432416
-
Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Abeta-induced cell death
-
Hitomi J., Katayama T., Eguchi Y., Kudo T., Taniguchi M., Koyama Y., Manabe T., Yamagishi S., Bando Y., Imaizumi K., Tsujimoto Y., Tohyama M. Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Abeta-induced cell death. J. Cell Biol. 2004, 165:347-356.
-
(2004)
J. Cell Biol.
, vol.165
, pp. 347-356
-
-
Hitomi, J.1
Katayama, T.2
Eguchi, Y.3
Kudo, T.4
Taniguchi, M.5
Koyama, Y.6
Manabe, T.7
Yamagishi, S.8
Bando, Y.9
Imaizumi, K.10
Tsujimoto, Y.11
Tohyama, M.12
-
123
-
-
38349169247
-
Presenilin-1 mutation activates the signaling pathway of caspase-4 in endoplasmic reticulum stress-induced apoptosis
-
Yukioka F., Matsuzaki S., Kawamoto K., Koyama Y., Hitomi J., Katayama T., Tohyama M. Presenilin-1 mutation activates the signaling pathway of caspase-4 in endoplasmic reticulum stress-induced apoptosis. Neurochem. Int. 2008, 52:683-687.
-
(2008)
Neurochem. Int.
, vol.52
, pp. 683-687
-
-
Yukioka, F.1
Matsuzaki, S.2
Kawamoto, K.3
Koyama, Y.4
Hitomi, J.5
Katayama, T.6
Tohyama, M.7
-
124
-
-
0035957929
-
Activation of caspase-12, an endoplastic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress
-
Yoneda T., Imaizumi K., Oono K., Yui D., Gomi F., Katayama T., Tohyama M. Activation of caspase-12, an endoplastic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress. J. Biol. Chem. 2001, 276:13935-13940.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 13935-13940
-
-
Yoneda, T.1
Imaizumi, K.2
Oono, K.3
Yui, D.4
Gomi, F.5
Katayama, T.6
Tohyama, M.7
-
125
-
-
0034698878
-
Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis
-
Nakagawa T., Yuan J. Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis. J. Cell Biol. 2000, 150:887-894.
-
(2000)
J. Cell Biol.
, vol.150
, pp. 887-894
-
-
Nakagawa, T.1
Yuan, J.2
-
126
-
-
78649960531
-
Calpain and caspase processing of caspase-12 contribute to the ER stress-induced cell death pathway in differentiated PC12 cells
-
Martinez J.A., Zhang Z., Svetlov S.I., Hayes R.L., Wang K.K., Larner S.F. Calpain and caspase processing of caspase-12 contribute to the ER stress-induced cell death pathway in differentiated PC12 cells. Apoptosis 2010, 15:1480-1493.
-
(2010)
Apoptosis
, vol.15
, pp. 1480-1493
-
-
Martinez, J.A.1
Zhang, Z.2
Svetlov, S.I.3
Hayes, R.L.4
Wang, K.K.5
Larner, S.F.6
-
128
-
-
78149487761
-
Caspase-12 dampens the immune response to malaria independently of the inflammasome by targeting NF-kappaB signaling
-
Labbe K., Miu J., Yeretssian G., Serghides L., Tam M., Finney C.A., Erdman L.K., Goulet M.L., Kain K.C., Stevenson M.M., Saleh M. Caspase-12 dampens the immune response to malaria independently of the inflammasome by targeting NF-kappaB signaling. J. Immunol. 2010, 185:5495-5502.
-
(2010)
J. Immunol.
, vol.185
, pp. 5495-5502
-
-
Labbe, K.1
Miu, J.2
Yeretssian, G.3
Serghides, L.4
Tam, M.5
Finney, C.A.6
Erdman, L.K.7
Goulet, M.L.8
Kain, K.C.9
Stevenson, M.M.10
Saleh, M.11
-
129
-
-
2342457148
-
Differential modulation of endotoxin responsiveness by human caspase-12 polymorphisms
-
Saleh M., Vaillancourt J.P., Graham R.K., Huyck M., Srinivasula S.M., Alnemri E.S., Steinberg M.H., Nolan V., Baldwin C.T., Hotchkiss R.S., Buchman T.G., Zehnbauer B.A., Hayden M.R., Farrer L.A., Roy S., Nicholson D.W. Differential modulation of endotoxin responsiveness by human caspase-12 polymorphisms. Nature 2004, 429:75-79.
-
(2004)
Nature
, vol.429
, pp. 75-79
-
-
Saleh, M.1
Vaillancourt, J.P.2
Graham, R.K.3
Huyck, M.4
Srinivasula, S.M.5
Alnemri, E.S.6
Steinberg, M.H.7
Nolan, V.8
Baldwin, C.T.9
Hotchkiss, R.S.10
Buchman, T.G.11
Zehnbauer, B.A.12
Hayden, M.R.13
Farrer, L.A.14
Roy, S.15
Nicholson, D.W.16
-
130
-
-
0041731979
-
Regulation of the expression and processing of caspase-12
-
Kalai M., Lamkanfi M., Denecker G., Boogmans M., Lippens S., Meeus A., Declercq W., Vandenabeele P. Regulation of the expression and processing of caspase-12. J. Cell Biol. 2003, 162:457-467.
-
(2003)
J. Cell Biol.
, vol.162
, pp. 457-467
-
-
Kalai, M.1
Lamkanfi, M.2
Denecker, G.3
Boogmans, M.4
Lippens, S.5
Meeus, A.6
Declercq, W.7
Vandenabeele, P.8
-
131
-
-
33845478357
-
The inflammatory caspases: guardians against infections and sepsis
-
Scott A.M., Saleh M. The inflammatory caspases: guardians against infections and sepsis. Cell Death Differ. 2007, 14:23-31.
-
(2007)
Cell Death Differ.
, vol.14
, pp. 23-31
-
-
Scott, A.M.1
Saleh, M.2
-
132
-
-
0037442851
-
ER stress induces caspase-8 activation, stimulating cytochrome c release and caspase-9 activation
-
Jimbo A., Fujita E., Kouroku Y., Ohnishi J., Inohara N., Kuida K., Sakamaki K., Yonehara S., Momoi T. ER stress induces caspase-8 activation, stimulating cytochrome c release and caspase-9 activation. Exp. Cell Res. 2003, 283:156-166.
-
(2003)
Exp. Cell Res.
, vol.283
, pp. 156-166
-
-
Jimbo, A.1
Fujita, E.2
Kouroku, Y.3
Ohnishi, J.4
Inohara, N.5
Kuida, K.6
Sakamaki, K.7
Yonehara, S.8
Momoi, T.9
-
133
-
-
79952348567
-
Caspase-4 directly activates caspase-9 in endoplasmic reticulum stress-induced apoptosis in SH-SY5Y cells
-
Yamamuro A., Kishino T., Ohshima Y., Yoshioka Y., Kimura T., Kasai A., Maeda S. Caspase-4 directly activates caspase-9 in endoplasmic reticulum stress-induced apoptosis in SH-SY5Y cells. J. Pharmacol. Sci. 2011, 115:239-243.
-
(2011)
J. Pharmacol. Sci.
, vol.115
, pp. 239-243
-
-
Yamamuro, A.1
Kishino, T.2
Ohshima, Y.3
Yoshioka, Y.4
Kimura, T.5
Kasai, A.6
Maeda, S.7
-
134
-
-
72949122555
-
Evidence that endoplasmic reticulum (ER) stress and caspase-4 activation occur in human neutrophils
-
Binet F., Chiasson S., Girard D. Evidence that endoplasmic reticulum (ER) stress and caspase-4 activation occur in human neutrophils. Biochem. Biophys. Res. Commun. 2010, 391:18-23.
-
(2010)
Biochem. Biophys. Res. Commun.
, vol.391
, pp. 18-23
-
-
Binet, F.1
Chiasson, S.2
Girard, D.3
-
135
-
-
33745242294
-
Involvement of caspase-2 and caspase-9 in endoplasmic reticulum stress-induced apoptosis: a role for the IAPs
-
Cheung H.H., Lynn Kelly N., Liston P., Korneluk R.G. Involvement of caspase-2 and caspase-9 in endoplasmic reticulum stress-induced apoptosis: a role for the IAPs. Exp. Cell Res. 2006, 312:2347-2357.
-
(2006)
Exp. Cell Res.
, vol.312
, pp. 2347-2357
-
-
Cheung, H.H.1
Lynn Kelly, N.2
Liston, P.3
Korneluk, R.G.4
-
136
-
-
53349101501
-
Caspase-2 functions upstream of mitochondria in endoplasmic reticulum stress-induced apoptosis by bortezomib in human myeloma cells
-
Gu H., Chen X., Gao G., Dong H. Caspase-2 functions upstream of mitochondria in endoplasmic reticulum stress-induced apoptosis by bortezomib in human myeloma cells. Mol. Cancer Ther. 2008, 7:2298-2307.
-
(2008)
Mol. Cancer Ther.
, vol.7
, pp. 2298-2307
-
-
Gu, H.1
Chen, X.2
Gao, G.3
Dong, H.4
-
137
-
-
29244470510
-
Bortezomib inhibits PKR-like endoplasmic reticulum (ER) kinase and induces apoptosis via ER stress in human pancreatic cancer cells
-
Nawrocki S.T., Carew J.S., Dunner K., Boise L.H., Chiao P.J., Huang P., Abbruzzese J.L., McConkey D.J. Bortezomib inhibits PKR-like endoplasmic reticulum (ER) kinase and induces apoptosis via ER stress in human pancreatic cancer cells. Cancer Res. 2005, 65:11510-11519.
-
(2005)
Cancer Res.
, vol.65
, pp. 11510-11519
-
-
Nawrocki, S.T.1
Carew, J.S.2
Dunner, K.3
Boise, L.H.4
Chiao, P.J.5
Huang, P.6
Abbruzzese, J.L.7
McConkey, D.J.8
-
138
-
-
84860868195
-
Six-transmembrane topology for Golgi anti-apoptotic protein (GAAP) and Bax inhibitor 1 (BI-1) provides model for the transmembrane Bax inhibitor-containing motif (TMBIM) family
-
Carrara G., Saraiva N., Gubser C., Johnson B.F., Smith G.L. Six-transmembrane topology for Golgi anti-apoptotic protein (GAAP) and Bax inhibitor 1 (BI-1) provides model for the transmembrane Bax inhibitor-containing motif (TMBIM) family. J. Biol. Chem. 2012, 287:15896-15905.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 15896-15905
-
-
Carrara, G.1
Saraiva, N.2
Gubser, C.3
Johnson, B.F.4
Smith, G.L.5
-
139
-
-
4143087106
-
BI-1 regulates an apoptosis pathway linked to endoplasmic reticulum stress
-
Chae H.J., Kim H.R., Xu C., Bailly-Maitre B., Krajewska M., Krajewski S., Banares S., Cui J., Digicaylioglu M., Ke N., Kitada S., Monosov E., Thomas M., Kress C.L., Babendure J.R., Tsien R.Y., Lipton S.A., Reed J.C. BI-1 regulates an apoptosis pathway linked to endoplasmic reticulum stress. Mol. Cell 2004, 15:355-366.
-
(2004)
Mol. Cell
, vol.15
, pp. 355-366
-
-
Chae, H.J.1
Kim, H.R.2
Xu, C.3
Bailly-Maitre, B.4
Krajewska, M.5
Krajewski, S.6
Banares, S.7
Cui, J.8
Digicaylioglu, M.9
Ke, N.10
Kitada, S.11
Monosov, E.12
Thomas, M.13
Kress, C.L.14
Babendure, J.R.15
Tsien, R.Y.16
Lipton, S.A.17
Reed, J.C.18
-
140
-
-
3242806002
-
BAX Inhibitor-1, an ancient cell death suppressor in animals and plants with prokaryotic relatives
-
Huckelhoven R. BAX Inhibitor-1, an ancient cell death suppressor in animals and plants with prokaryotic relatives. Apoptosis 2004, 9:299-307.
-
(2004)
Apoptosis
, vol.9
, pp. 299-307
-
-
Huckelhoven, R.1
-
141
-
-
42049114828
-
The Bax Inhibitor-1 (BI-1) family in apoptosis and tumorigenesis
-
Reimers K., Choi C.Y., Bucan V., Vogt P.M. The Bax Inhibitor-1 (BI-1) family in apoptosis and tumorigenesis. Curr. Mol. Med. 2008, 8:148-156.
-
(2008)
Curr. Mol. Med.
, vol.8
, pp. 148-156
-
-
Reimers, K.1
Choi, C.Y.2
Bucan, V.3
Vogt, P.M.4
-
142
-
-
79951579431
-
A shear stress responsive gene product PP1201 protects against Fas-mediated apoptosis by reducing Fas expression on the cell surface
-
Shukla S., Fujita K., Xiao Q., Liao Z., Garfield S., Srinivasula S.M. A shear stress responsive gene product PP1201 protects against Fas-mediated apoptosis by reducing Fas expression on the cell surface. Apoptosis 2011, 16:162-173.
-
(2011)
Apoptosis
, vol.16
, pp. 162-173
-
-
Shukla, S.1
Fujita, K.2
Xiao, Q.3
Liao, Z.4
Garfield, S.5
Srinivasula, S.M.6
-
143
-
-
33645793504
-
RECS1 deficiency in mice induces susceptibility to cystic medial degeneration
-
Zhao H., Ito A., Kimura S.H., Yabuta N., Sakai N., Ikawa M., Okabe M., Matsuzawa Y., Yamashita S., Nojima H. RECS1 deficiency in mice induces susceptibility to cystic medial degeneration. Genes Genet. Syst. 2006, 81:41-50.
-
(2006)
Genes Genet. Syst.
, vol.81
, pp. 41-50
-
-
Zhao, H.1
Ito, A.2
Kimura, S.H.3
Yabuta, N.4
Sakai, N.5
Ikawa, M.6
Okabe, M.7
Matsuzawa, Y.8
Yamashita, S.9
Nojima, H.10
-
144
-
-
34548624517
-
Lifeguard/neuronal membrane protein 35 regulates Fas ligand-mediated apoptosis in neurons via microdomain recruitment
-
Fernandez M., Segura M.F., Sole C., Colino A., Comella J.X., Cena V. Lifeguard/neuronal membrane protein 35 regulates Fas ligand-mediated apoptosis in neurons via microdomain recruitment. J. Neurochem. 2007, 103:190-203.
-
(2007)
J. Neurochem.
, vol.103
, pp. 190-203
-
-
Fernandez, M.1
Segura, M.F.2
Sole, C.3
Colino, A.4
Comella, J.X.5
Cena, V.6
-
145
-
-
33644515957
-
Cytoprotective gene bi-1 is required for intrinsic protection from endoplasmic reticulum stress and ischemia-reperfusion injury
-
Bailly-Maitre B., Fondevila C., Kaldas F., Droin N., Luciano F., Ricci J.E., Croxton R., Krajewska M., Zapata J.M., Kupiec-Weglinski J.W., Farmer D., Reed J.C. Cytoprotective gene bi-1 is required for intrinsic protection from endoplasmic reticulum stress and ischemia-reperfusion injury. Proc. Natl. Acad. Sci. U. S. A. 2006, 103:2809-2814.
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 2809-2814
-
-
Bailly-Maitre, B.1
Fondevila, C.2
Kaldas, F.3
Droin, N.4
Luciano, F.5
Ricci, J.E.6
Croxton, R.7
Krajewska, M.8
Zapata, J.M.9
Kupiec-Weglinski, J.W.10
Farmer, D.11
Reed, J.C.12
-
146
-
-
62549129467
-
BAX inhibitor-1 is a negative regulator of the ER stress sensor IRE1alpha
-
Lisbona F., Rojas-Rivera D., Thielen P., Zamorano S., Todd D., Martinon F., Glavic A., Kress C., Lin J.H., Walter P., Reed J.C., Glimcher L.H., Hetz C. BAX inhibitor-1 is a negative regulator of the ER stress sensor IRE1alpha. Mol. Cell 2009, 33:679-691.
-
(2009)
Mol. Cell
, vol.33
, pp. 679-691
-
-
Lisbona, F.1
Rojas-Rivera, D.2
Thielen, P.3
Zamorano, S.4
Todd, D.5
Martinon, F.6
Glavic, A.7
Kress, C.8
Lin, J.H.9
Walter, P.10
Reed, J.C.11
Glimcher, L.H.12
Hetz, C.13
-
147
-
-
79960642801
-
A yeast BH3-only protein mediates the mitochondrial pathway of apoptosis
-
Buttner S., Ruli D., Vogtle F.N., Galluzzi L., Moitzi B., Eisenberg T., Kepp O., Habernig L., Carmona-Gutierrez D., Rockenfeller P., Laun P., Breitenbach M., Khoury C., Frohlich K.U., Rechberger G., Meisinger C., Kroemer G., Madeo F. A yeast BH3-only protein mediates the mitochondrial pathway of apoptosis. EMBO J. 2011, 30:2779-2792.
-
(2011)
EMBO J.
, vol.30
, pp. 2779-2792
-
-
Buttner, S.1
Ruli, D.2
Vogtle, F.N.3
Galluzzi, L.4
Moitzi, B.5
Eisenberg, T.6
Kepp, O.7
Habernig, L.8
Carmona-Gutierrez, D.9
Rockenfeller, P.10
Laun, P.11
Breitenbach, M.12
Khoury, C.13
Frohlich, K.U.14
Rechberger, G.15
Meisinger, C.16
Kroemer, G.17
Madeo, F.18
-
148
-
-
0345059069
-
Evolutionarily conserved cytoprotection provided by Bax Inhibitor-1 homologs from animals, plants, and yeast
-
Chae H.J., Ke N., Kim H.R., Chen S., Godzik A., Dickman M., Reed J.C. Evolutionarily conserved cytoprotection provided by Bax Inhibitor-1 homologs from animals, plants, and yeast. Gene 2003, 323:101-113.
-
(2003)
Gene
, vol.323
, pp. 101-113
-
-
Chae, H.J.1
Ke, N.2
Kim, H.R.3
Chen, S.4
Godzik, A.5
Dickman, M.6
Reed, J.C.7
-
149
-
-
0031993255
-
Bax inhibitor-1, a mammalian apoptosis suppressor identified by functional screening in yeast
-
Xu Q., Reed J.C. Bax inhibitor-1, a mammalian apoptosis suppressor identified by functional screening in yeast. Mol. Cell 1998, 1:337-346.
-
(1998)
Mol. Cell
, vol.1
, pp. 337-346
-
-
Xu, Q.1
Reed, J.C.2
-
151
-
-
14944347389
-
BI-1 protects cells from oxygen glucose deprivation by reducing the calcium content of the endoplasmic reticulum
-
Westphalen B.C., Wessig J., Leypoldt F., Arnold S., Methner A. BI-1 protects cells from oxygen glucose deprivation by reducing the calcium content of the endoplasmic reticulum. Cell Death Differ. 2005, 12:304-306.
-
(2005)
Cell Death Differ.
, vol.12
, pp. 304-306
-
-
Westphalen, B.C.1
Wessig, J.2
Leypoldt, F.3
Arnold, S.4
Methner, A.5
-
152
-
-
0842313320
-
Dissection of arabidopsis Bax inhibitor-1 suppressing Bax-, hydrogen peroxide-, and salicylic acid-induced cell death
-
Kawai-Yamada M., Ohori Y., Uchimiya H. Dissection of arabidopsis Bax inhibitor-1 suppressing Bax-, hydrogen peroxide-, and salicylic acid-induced cell death. Plant Cell 2004, 16:21-32.
-
(2004)
Plant Cell
, vol.16
, pp. 21-32
-
-
Kawai-Yamada, M.1
Ohori, Y.2
Uchimiya, H.3
-
153
-
-
78651364538
-
Endoplasmic reticulum protein BI-1 modulates unfolded protein response signaling and protects against stroke and traumatic brain injury
-
Krajewska M., Xu L., Xu W., Krajewski S., Kress C.L., Cui J., Yang L., Irie F., Yamaguchi Y., Lipton S.A., Reed J.C. Endoplasmic reticulum protein BI-1 modulates unfolded protein response signaling and protects against stroke and traumatic brain injury. Brain Res. 2011, 1370:227-237.
-
(2011)
Brain Res.
, vol.1370
, pp. 227-237
-
-
Krajewska, M.1
Xu, L.2
Xu, W.3
Krajewski, S.4
Kress, C.L.5
Cui, J.6
Yang, L.7
Irie, F.8
Yamaguchi, Y.9
Lipton, S.A.10
Reed, J.C.11
-
154
-
-
77949883045
-
Hepatic Bax inhibitor-1 inhibits IRE1alpha and protects from obesity-associated insulin resistance and glucose intolerance
-
Bailly-Maitre B., Belgardt B.F., Jordan S.D., Coornaert B., von Freyend M.J., Kleinridders A., Mauer J., Cuddy M., Kress C.L., Willmes D., Essig M., Hampel B., Protzer U., Reed J.C., Bruning J.C. Hepatic Bax inhibitor-1 inhibits IRE1alpha and protects from obesity-associated insulin resistance and glucose intolerance. J. Biol. Chem. 2010, 285:6198-6207.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 6198-6207
-
-
Bailly-Maitre, B.1
Belgardt, B.F.2
Jordan, S.D.3
Coornaert, B.4
von Freyend, M.J.5
Kleinridders, A.6
Mauer, J.7
Cuddy, M.8
Kress, C.L.9
Willmes, D.10
Essig, M.11
Hampel, B.12
Protzer, U.13
Reed, J.C.14
Bruning, J.C.15
-
155
-
-
69949099282
-
Human Golgi antiapoptotic protein modulates intracellular calcium fluxes
-
de Mattia F., Gubser C., van Dommelen M.M., Visch H.J., Distelmaier F., Postigo A., Luyten T., Parys J.B., de Smedt H., Smith G.L., Willems P.H., van Kuppeveld F.J. Human Golgi antiapoptotic protein modulates intracellular calcium fluxes. Mol. Biol. Cell 2009, 20:3638-3645.
-
(2009)
Mol. Biol. Cell
, vol.20
, pp. 3638-3645
-
-
de Mattia, F.1
Gubser, C.2
van Dommelen, M.M.3
Visch, H.J.4
Distelmaier, F.5
Postigo, A.6
Luyten, T.7
Parys, J.B.8
de Smedt, H.9
Smith, G.L.10
Willems, P.H.11
van Kuppeveld, F.J.12
-
156
-
-
78650169392
-
Bcl-2 proteins regulate ER membrane permeability to luminal proteins during ER stress-induced apoptosis
-
Wang X., Olberding K.E., White C., Li C. Bcl-2 proteins regulate ER membrane permeability to luminal proteins during ER stress-induced apoptosis. Cell Death Differ. 2011, 18:38-47.
-
(2011)
Cell Death Differ.
, vol.18
, pp. 38-47
-
-
Wang, X.1
Olberding, K.E.2
White, C.3
Li, C.4
-
157
-
-
0034663829
-
TBID, a membrane-targeted death ligand, oligomerizes BAK to release cytochrome c
-
Wei M.C., Lindsten T., Mootha V.K., Weiler S., Gross A., Ashiya M., Thompson C.B., Korsmeyer S.J. tBID, a membrane-targeted death ligand, oligomerizes BAK to release cytochrome c. Genes Dev. 2000, 14:2060-2071.
-
(2000)
Genes Dev.
, vol.14
, pp. 2060-2071
-
-
Wei, M.C.1
Lindsten, T.2
Mootha, V.K.3
Weiler, S.4
Gross, A.5
Ashiya, M.6
Thompson, C.B.7
Korsmeyer, S.J.8
-
158
-
-
67650632688
-
The tumor suppressor Par-4 activates an extrinsic pathway for apoptosis
-
Burikhanov R., Zhao Y., Goswami A., Qiu S., Schwarze S.R., Rangnekar V.M. The tumor suppressor Par-4 activates an extrinsic pathway for apoptosis. Cell 2009, 138:377-388.
-
(2009)
Cell
, vol.138
, pp. 377-388
-
-
Burikhanov, R.1
Zhao, Y.2
Goswami, A.3
Qiu, S.4
Schwarze, S.R.5
Rangnekar, V.M.6
-
159
-
-
78649246847
-
Inhibitors of protein disulfide isomerase suppress apoptosis induced by misfolded proteins
-
Hoffstrom B.G., Kaplan A., Letso R., Schmid R.S., Turmel G.J., Lo D.C., Stockwell B.R. Inhibitors of protein disulfide isomerase suppress apoptosis induced by misfolded proteins. Nat. Chem. Biol. 2010, 6:900-906.
-
(2010)
Nat. Chem. Biol.
, vol.6
, pp. 900-906
-
-
Hoffstrom, B.G.1
Kaplan, A.2
Letso, R.3
Schmid, R.S.4
Turmel, G.J.5
Lo, D.C.6
Stockwell, B.R.7
-
160
-
-
0027751663
-
The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
-
Lee R.C., Feinbaum R.L., Ambros V. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 1993, 75:843-854.
-
(1993)
Cell
, vol.75
, pp. 843-854
-
-
Lee, R.C.1
Feinbaum, R.L.2
Ambros, V.3
-
161
-
-
84876902510
-
Micro(RNA)managing endoplasmic reticulum stress
-
Byrd A.E., Brewer J.W. Micro(RNA)managing endoplasmic reticulum stress. IUBMB Life 2013, 65:373-381.
-
(2013)
IUBMB Life
, vol.65
, pp. 373-381
-
-
Byrd, A.E.1
Brewer, J.W.2
-
162
-
-
84879155370
-
Endoplasmic reticulum stress signaling: the microRNA connection
-
Maurel M., Chevet E. Endoplasmic reticulum stress signaling: the microRNA connection. Am. J .Physiol. Cell Physiol. 2013, 304:C1117-1126.
-
(2013)
Am. J .Physiol. Cell Physiol.
, vol.304
-
-
Maurel, M.1
Chevet, E.2
-
163
-
-
79955520100
-
A CHOP-regulated microRNA controls rhodopsin expression
-
Behrman S., Acosta-Alvear D., Walter P. A CHOP-regulated microRNA controls rhodopsin expression. J. Cell Biol. 2011, 192:919-927.
-
(2011)
J. Cell Biol.
, vol.192
, pp. 919-927
-
-
Behrman, S.1
Acosta-Alvear, D.2
Walter, P.3
-
164
-
-
84860297865
-
MicroRNA-30c-2* limits expression of proadaptive factor XBP1 in the unfolded protein response
-
Byrd A.E., Aragon I.V., Brewer J.W. MicroRNA-30c-2* limits expression of proadaptive factor XBP1 in the unfolded protein response. J. Cell Biol. 2012, 196:689-698.
-
(2012)
J. Cell Biol.
, vol.196
, pp. 689-698
-
-
Byrd, A.E.1
Aragon, I.V.2
Brewer, J.W.3
-
165
-
-
84863124865
-
ER stress negatively modulates the expression of the miR-199a/214 cluster to regulates tumor survival and progression in human hepatocellular cancer
-
Duan Q., Wang X., Gong W., Ni L., Chen C., He X., Chen F., Yang L., Wang P., Wang D.W. ER stress negatively modulates the expression of the miR-199a/214 cluster to regulates tumor survival and progression in human hepatocellular cancer. PLoS One 2012, 7:e31518.
-
(2012)
PLoS One
, vol.7
-
-
Duan, Q.1
Wang, X.2
Gong, W.3
Ni, L.4
Chen, C.5
He, X.6
Chen, F.7
Yang, L.8
Wang, P.9
Wang, D.W.10
-
166
-
-
84876906034
-
MicroRNA-199a-5p protects hepatocytes from bile acid-induced sustained endoplasmic reticulum stress
-
Dai B.H., Geng L., Wang Y., Sui C.J., Xie F., Shen R.X., Shen W.F., Yang J.M. microRNA-199a-5p protects hepatocytes from bile acid-induced sustained endoplasmic reticulum stress. Cell Death Dis. 2013, 4:e604.
-
(2013)
Cell Death Dis.
, vol.4
-
-
Dai, B.H.1
Geng, L.2
Wang, Y.3
Sui, C.J.4
Xie, F.5
Shen, R.X.6
Shen, W.F.7
Yang, J.M.8
-
167
-
-
84878047476
-
MicroRNA-1291-mediated silencing of IRE1alpha enhances Glypican-3 expression
-
Maurel M., Dejeans N., Taouji S., Chevet E., Grosset C.F. MicroRNA-1291-mediated silencing of IRE1alpha enhances Glypican-3 expression. RNA 2013, 19:778-788.
-
(2013)
RNA
, vol.19
, pp. 778-788
-
-
Maurel, M.1
Dejeans, N.2
Taouji, S.3
Chevet, E.4
Grosset, C.F.5
-
168
-
-
84863484585
-
Perk-dependent repression of miR-106b-25 cluster is required for ER stress-induced apoptosis
-
Gupta S., Read D.E., Deepti A., Cawley K., Gupta A., Oommen D., Verfaillie T., Matus S., Smith M.A., Mott J.L., Agostinis P., Hetz C., Samali A. Perk-dependent repression of miR-106b-25 cluster is required for ER stress-induced apoptosis. Cell Death Dis. 2012, 3:e333.
-
(2012)
Cell Death Dis.
, vol.3
-
-
Gupta, S.1
Read, D.E.2
Deepti, A.3
Cawley, K.4
Gupta, A.5
Oommen, D.6
Verfaillie, T.7
Matus, S.8
Smith, M.A.9
Mott, J.L.10
Agostinis, P.11
Hetz, C.12
Samali, A.13
-
169
-
-
79960077539
-
Gene expression profiling indicate role of ER stress in miR-23a~24-2 cluster induced apoptosis in HEK293T cells
-
Chhabra R., Dubey R., Saini N. Gene expression profiling indicate role of ER stress in miR-23a~24-2 cluster induced apoptosis in HEK293T cells. RNA Biol. 2011, 8:648-664.
-
(2011)
RNA Biol.
, vol.8
, pp. 648-664
-
-
Chhabra, R.1
Dubey, R.2
Saini, N.3
-
170
-
-
84869087503
-
MiR-211 is a prosurvival microRNA that regulates chop expression in a PERK-dependent manner
-
Chitnis N.S., Pytel D., Bobrovnikova-Marjon E., Pant D., Zheng H., Maas N.L., Frederick B., Kushner J.A., Chodosh L.A., Koumenis C., Fuchs S.Y., Diehl J.A. miR-211 is a prosurvival microRNA that regulates chop expression in a PERK-dependent manner. Mol. Cell 2012, 48:353-364.
-
(2012)
Mol. Cell
, vol.48
, pp. 353-364
-
-
Chitnis, N.S.1
Pytel, D.2
Bobrovnikova-Marjon, E.3
Pant, D.4
Zheng, H.5
Maas, N.L.6
Frederick, B.7
Kushner, J.A.8
Chodosh, L.A.9
Koumenis, C.10
Fuchs, S.Y.11
Diehl, J.A.12
-
171
-
-
0033634641
-
Perk is essential for translational regulation and cell survival during the unfolded protein response
-
Harding H.P., Zhang Y., Bertolotti A., Zeng H., Ron D. Perk is essential for translational regulation and cell survival during the unfolded protein response. Mol. Cell 2000, 5:897-904.
-
(2000)
Mol. Cell
, vol.5
, pp. 897-904
-
-
Harding, H.P.1
Zhang, Y.2
Bertolotti, A.3
Zeng, H.4
Ron, D.5
-
172
-
-
0035957653
-
Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death
-
Wei M.C., Zong W.X., Cheng E.H., Lindsten T., Panoutsakopoulou V., Ross A.J., Roth K.A., MacGregor G.R., Thompson C.B., Korsmeyer S.J. Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death. Science 2001, 292:727-730.
-
(2001)
Science
, vol.292
, pp. 727-730
-
-
Wei, M.C.1
Zong, W.X.2
Cheng, E.H.3
Lindsten, T.4
Panoutsakopoulou, V.5
Ross, A.J.6
Roth, K.A.7
MacGregor, G.R.8
Thompson, C.B.9
Korsmeyer, S.J.10
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