Targeting autophagy in neurodegenerative diseases

Trends in Pharmacological Sciences

Volumn 35, Issue 11, 2014, Pages 583-591

  Vidal, René L ^a,b   Matus, Soledad ^a,b   Bargsted, Leslie ^b,c   Hetz, Claudio ^a,b,c,d  

^a Neurounion Biomedical Foundation CENPAR ^*  (Chile)

^b UNIVERSITY OF CHILE   (Chile)

^c UNIVERSITY OF CHILE   (Chile)

^d HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

aggregation; autophagy; Beclin 1; mTOR; neurodegenerative disease; rapamycin

Indexed keywords

BECLIN 1; RAPAMYCIN; TREHALOSE; APOPTOSIS REGULATORY PROTEIN;

ALZHEIMER DISEASE; AMYOTROPHIC LATERAL SCLEROSIS; AUTOPHAGY; BIOACCUMULATION; CELL LEVEL; COMPLEX FORMATION; DEGENERATIVE DISEASE; DISEASE ACTIVITY; DISEASE ASSOCIATION; DRUG EFFECT; DRUG MECHANISM; DRUG RESPONSE; DRUG STRUCTURE; FRONTOTEMPORAL DEMENTIA; GENE THERAPY; HUMAN; HUNTINGTON CHOREA; MOLECULAR DYNAMICS; MOLECULAR PATHOLOGY; NONHUMAN; OCULOPHARYNGEAL MUSCULAR DYSTROPHY; OUTCOME ASSESSMENT; PARKINSON DISEASE; PROTEIN DEGRADATION; PROTEIN HOMEOSTASIS; PROTEIN UNFOLDING; REVIEW; SIGNAL TRANSDUCTION; TARGET CELL DESTRUCTION; TAUOPATHY; ANIMAL; DRUG EFFECTS; GENETICS; NEURODEGENERATIVE DISEASES; PATHOLOGY;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; GENETIC THERAPY; HUMANS; NEURODEGENERATIVE DISEASES;

EID: 84908386761     PISSN: 01656147     EISSN: 18733735     Source Type: Journal    
DOI: 10.1016/j.tips.2014.09.002     Document Type: Review

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