메뉴 건너뛰기




Volumn 6, Issue 4, 2017, Pages 601-609

A New Era of Genome Integration - Simply Cut and Paste!

Author keywords

genome integration; metabolic engineering; programmable nucleases; synthetic biology

Indexed keywords

ANTIBIOTIC AGENT; DOUBLE STRANDED DNA; NUCLEASE; OLIGODEOXYRIBONUCLEOTIDE; SINGLE STRANDED OLIGODEOXYRIBONUCLEOTIDE; UNCLASSIFIED DRUG; ENDONUCLEASE;

EID: 85018466549     PISSN: None     EISSN: 21615063     Source Type: Journal    
DOI: 10.1021/acssynbio.6b00331     Document Type: Review
Times cited : (32)

References (121)
  • 1
    • 84655170273 scopus 로고    scopus 로고
    • Safe harbours for the integration of new DNA in the human genome
    • Sadelain, M., Papapetrou, E. P., and Bushman, F. D. (2012) Safe harbours for the integration of new DNA in the human genome Nat. Rev. Cancer 12, 51-58 10.1038/nrc3179
    • (2012) Nat. Rev. Cancer , vol.12 , pp. 51-58
    • Sadelain, M.1    Papapetrou, E.P.2    Bushman, F.D.3
  • 2
    • 84900655950 scopus 로고    scopus 로고
    • Enhancement of natamycin production on Streptomyces gilvosporeus by chromosomal integration of the Vitreoscilla hemoglobin gene (vgb)
    • Wang, S., Liu, F., Hou, Z., Zong, G., Zhu, X., and Ling, P. (2014) Enhancement of natamycin production on Streptomyces gilvosporeus by chromosomal integration of the Vitreoscilla hemoglobin gene (vgb) World J. Microbiol. Biotechnol. 30, 1369-1376 10.1007/s11274-013-1561-4
    • (2014) World J. Microbiol. Biotechnol. , vol.30 , pp. 1369-1376
    • Wang, S.1    Liu, F.2    Hou, Z.3    Zong, G.4    Zhu, X.5    Ling, P.6
  • 4
    • 84872415347 scopus 로고    scopus 로고
    • Characterization of plasmid burden and copy number in Saccharomyces cerevisiae for optimization of metabolic engineering applications
    • Karim, A. S., Curran, K. A., and Alper, H. S. (2013) Characterization of plasmid burden and copy number in Saccharomyces cerevisiae for optimization of metabolic engineering applications FEMS Yeast Res. 13, 107-116 10.1111/1567-1364.12016
    • (2013) FEMS Yeast Res. , vol.13 , pp. 107-116
    • Karim, A.S.1    Curran, K.A.2    Alper, H.S.3
  • 5
    • 84857053335 scopus 로고    scopus 로고
    • Introduction and expression of genes for metabolic engineering applications in Saccharomyces cerevisiae
    • Da Silva, N. A. and Srikrishnan, S. (2012) Introduction and expression of genes for metabolic engineering applications in Saccharomyces cerevisiae FEMS Yeast Res. 12, 197-214 10.1111/j.1567-1364.2011.00769.x
    • (2012) FEMS Yeast Res. , vol.12 , pp. 197-214
    • Da Silva, N.A.1    Srikrishnan, S.2
  • 6
    • 84927920113 scopus 로고    scopus 로고
    • CRISPR-Cas system enables fast and simple genome editing of industrial Saccharomyces cerevisiae strains
    • Stovicek, V., Borodina, I., and Forster, J. (2015) CRISPR-Cas system enables fast and simple genome editing of industrial Saccharomyces cerevisiae strains Metab. Eng. Commun. 2, 13-22 10.1016/j.meteno.2015.03.001
    • (2015) Metab. Eng. Commun. , vol.2 , pp. 13-22
    • Stovicek, V.1    Borodina, I.2    Forster, J.3
  • 7
    • 84952682854 scopus 로고    scopus 로고
    • CRISPR/Cas9 advances engineering of microbial cell factories
    • Jakočiunas, T., Jensen, M. K., and Keasling, J. D. (2016) CRISPR/Cas9 advances engineering of microbial cell factories Metab. Eng. 34, 44-59 10.1016/j.ymben.2015.12.003
    • (2016) Metab. Eng. , vol.34 , pp. 44-59
    • Jakočiunas, T.1    Jensen, M.K.2    Keasling, J.D.3
  • 9
    • 84904862031 scopus 로고    scopus 로고
    • Engineering of chromosomal wax ester synthase integrated Saccharomyces cerevisiae mutants for improved biosynthesis of fatty acid ethyl esters
    • Shi, S., Valle-Rodríguez, J. O., Siewers, V., and Nielsen, J. (2014) Engineering of chromosomal wax ester synthase integrated Saccharomyces cerevisiae mutants for improved biosynthesis of fatty acid ethyl esters Biotechnol. Bioeng. 111, 1740-1747 10.1002/bit.25234
    • (2014) Biotechnol. Bioeng. , vol.111 , pp. 1740-1747
    • Shi, S.1    Valle-Rodríguez, J.O.2    Siewers, V.3    Nielsen, J.4
  • 10
    • 0345166826 scopus 로고    scopus 로고
    • Chromosomal site-specific double-strand breaks are efficiently targeted for repair by oligonucleotides in yeast
    • Storici, F., Durham, C. L., Gordenin, D. A., and Resnick, M. A. (2003) Chromosomal site-specific double-strand breaks are efficiently targeted for repair by oligonucleotides in yeast Proc. Natl. Acad. Sci. U. S. A. 100, 14994-14999 10.1073/pnas.2036296100
    • (2003) Proc. Natl. Acad. Sci. U. S. A. , vol.100 , pp. 14994-14999
    • Storici, F.1    Durham, C.L.2    Gordenin, D.A.3    Resnick, M.A.4
  • 12
    • 84947474587 scopus 로고    scopus 로고
    • An integrated system for precise genome modification in Escherichia coli
    • Tas, H., Nguyen, C. T., Patel, R., Kim, N. H., and Kuhlman, T. E. (2015) An integrated system for precise genome modification in Escherichia coli PLoS One 10, e0136963 10.1371/journal.pone.0136963
    • (2015) PLoS One , vol.10 , pp. e0136963
    • Tas, H.1    Nguyen, C.T.2    Patel, R.3    Kim, N.H.4    Kuhlman, T.E.5
  • 13
    • 78650416018 scopus 로고    scopus 로고
    • Evolution of I-SceI homing endonucleases with increased DNA recognition site specificity
    • Joshi, R., Ho, K. K., Tenney, K., Chen, J.-H., Golden, B. L., and Gimble, F. S. (2011) Evolution of I-SceI homing endonucleases with increased DNA recognition site specificity J. Mol. Biol. 405, 185-200 10.1016/j.jmb.2010.10.029
    • (2011) J. Mol. Biol. , vol.405 , pp. 185-200
    • Joshi, R.1    Ho, K.K.2    Tenney, K.3    Chen, J.-H.4    Golden, B.L.5    Gimble, F.S.6
  • 14
    • 80053064386 scopus 로고    scopus 로고
    • Reiterative recombination for the in vivo assembly of libraries of multigene pathways
    • Wingler, L. M. and Cornish, V. W. (2011) Reiterative recombination for the in vivo assembly of libraries of multigene pathways Proc. Natl. Acad. Sci. U. S. A. 108, 15135-15140 10.1073/pnas.1100507108
    • (2011) Proc. Natl. Acad. Sci. U. S. A. , vol.108 , pp. 15135-15140
    • Wingler, L.M.1    Cornish, V.W.2
  • 15
    • 84878568502 scopus 로고    scopus 로고
    • Generation of an HIV resistant T-cell line by targeted "stacking" of restriction factors
    • Voit, R. A., McMahon, M. A., Sawyer, S. L., and Porteus, M. H. (2013) Generation of an HIV resistant T-cell line by targeted "stacking" of restriction factors Mol. Ther. 21, 786-795 10.1038/mt.2012.284
    • (2013) Mol. Ther. , vol.21 , pp. 786-795
    • Voit, R.A.1    McMahon, M.A.2    Sawyer, S.L.3    Porteus, M.H.4
  • 16
    • 84860736700 scopus 로고    scopus 로고
    • High-efficiency TALEN-based gene editing produces disease-resistant rice
    • Li, T., Liu, B., Spalding, M. H., Weeks, D. P., and Yang, B. (2012) High-efficiency TALEN-based gene editing produces disease-resistant rice Nat. Biotechnol. 30, 390-392 10.1038/nbt.2199
    • (2012) Nat. Biotechnol. , vol.30 , pp. 390-392
    • Li, T.1    Liu, B.2    Spalding, M.H.3    Weeks, D.P.4    Yang, B.5
  • 17
    • 84876575031 scopus 로고    scopus 로고
    • Genome engineering in Saccharomyces cerevisiae using CRISPR-Cas systems
    • DiCarlo, J. E., Norville, J. E., Mali, P., Rios, X., Aach, J., and Church, G. M. (2013) Genome engineering in Saccharomyces cerevisiae using CRISPR-Cas systems Nucleic Acids Res. 41, 4336-4343 10.1093/nar/gkt135
    • (2013) Nucleic Acids Res. , vol.41 , pp. 4336-4343
    • DiCarlo, J.E.1    Norville, J.E.2    Mali, P.3    Rios, X.4    Aach, J.5    Church, G.M.6
  • 19
    • 84898778301 scopus 로고    scopus 로고
    • A guide to genome engineering with programmable nucleases
    • Kim, H. and Kim, J.-S. (2014) A guide to genome engineering with programmable nucleases Nat. Rev. Genet. 15, 321-334 10.1038/nrg3686
    • (2014) Nat. Rev. Genet. , vol.15 , pp. 321-334
    • Kim, H.1    Kim, J.-S.2
  • 20
    • 84902185906 scopus 로고    scopus 로고
    • Genome engineering with targetable nucleases
    • Carroll, D. (2014) Genome engineering with targetable nucleases Annu. Rev. Biochem. 83, 409-439 10.1146/annurev-biochem-060713-035418
    • (2014) Annu. Rev. Biochem. , vol.83 , pp. 409-439
    • Carroll, D.1
  • 21
    • 84954289827 scopus 로고    scopus 로고
    • Genome editing in human pluripotent stem cells: Approaches, pitfalls, and solutions
    • Hendriks, W. T., Warren, C. R., and Cowan, C. A. (2016) Genome editing in human pluripotent stem cells: approaches, pitfalls, and solutions Cell Stem Cell 18, 53-65 10.1016/j.stem.2015.12.002
    • (2016) Cell Stem Cell , vol.18 , pp. 53-65
    • Hendriks, W.T.1    Warren, C.R.2    Cowan, C.A.3
  • 23
    • 84979746885 scopus 로고    scopus 로고
    • EasyClone-MarkerFree: A vector toolkit for marker-less integration of genes into Saccharomyces cerevisiae via CRISPR-Cas9
    • Jessop-Fabre, M. M., Jakočiunas, T., Stovicek, V., Dai, Z., Jensen, M. K., Keasling, J. D., and Borodina, I. (2016) EasyClone-MarkerFree: A vector toolkit for marker-less integration of genes into Saccharomyces cerevisiae via CRISPR-Cas9 Biotechnol. J. 11, 1110-1117 10.1002/biot.201600147
    • (2016) Biotechnol. J. , vol.11 , pp. 1110-1117
    • Jessop-Fabre, M.M.1    Jakočiunas, T.2    Stovicek, V.3    Dai, Z.4    Jensen, M.K.5    Keasling, J.D.6    Borodina, I.7
  • 24
    • 84988917002 scopus 로고    scopus 로고
    • Construction of plasmids with tunable copy numbers in Saccharomyces cerevisiae and their applications in pathway optimization and multiplex genome integration
    • Lian, J., Jin, R., and Zhao, H. (2016) Construction of plasmids with tunable copy numbers in Saccharomyces cerevisiae and their applications in pathway optimization and multiplex genome integration Biotechnol. Bioeng. 113, 2462-2473 10.1002/bit.26004
    • (2016) Biotechnol. Bioeng. , vol.113 , pp. 2462-2473
    • Lian, J.1    Jin, R.2    Zhao, H.3
  • 25
    • 84875712361 scopus 로고    scopus 로고
    • TALEN-mediated precise genome modification by homologous recombination in zebrafish
    • Zu, Y., Tong, X., Wang, Z., Liu, D., Pan, R., Li, Z., Hu, Y., Luo, Z., Huang, P., and Wu, Q. (2013) TALEN-mediated precise genome modification by homologous recombination in zebrafish Nat. Methods 10, 329-331 10.1038/nmeth.2374
    • (2013) Nat. Methods , vol.10 , pp. 329-331
    • Zu, Y.1    Tong, X.2    Wang, Z.3    Liu, D.4    Pan, R.5    Li, Z.6    Hu, Y.7    Luo, Z.8    Huang, P.9    Wu, Q.10
  • 26
    • 84876959581 scopus 로고    scopus 로고
    • Advances in mammalian cell line development technologies for recombinant protein production
    • Lai, T., Yang, Y., and Ng, S. K. (2013) Advances in mammalian cell line development technologies for recombinant protein production Pharmaceuticals 6, 579-603 10.3390/ph6050579
    • (2013) Pharmaceuticals , vol.6 , pp. 579-603
    • Lai, T.1    Yang, Y.2    Ng, S.K.3
  • 27
    • 84941956073 scopus 로고    scopus 로고
    • CRISPR/Cas9-mediated genome editing and gene replacement in plants: Transitioning from lab to field
    • Schaeffer, S. M. and Nakata, P. A. (2015) CRISPR/Cas9-mediated genome editing and gene replacement in plants: transitioning from lab to field Plant Sci. 240, 130-142 10.1016/j.plantsci.2015.09.011
    • (2015) Plant Sci. , vol.240 , pp. 130-142
    • Schaeffer, S.M.1    Nakata, P.A.2
  • 28
    • 84876161358 scopus 로고    scopus 로고
    • Alternative end-joining mechanisms: A historical perspective
    • Decottignies, A. (2013) Alternative end-joining mechanisms: a historical perspective Front. Genet. 4, 1-7 10.3389/fgene.2013.00048
    • (2013) Front. Genet. , vol.4 , pp. 1-7
    • Decottignies, A.1
  • 29
    • 0038799991 scopus 로고    scopus 로고
    • Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae
    • Pâques, F. and Haber, J. E. (1999) Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae Microbiol. Mol. Biol. Rev. 63, 349-404
    • (1999) Microbiol. Mol. Biol. Rev. , vol.63 , pp. 349-404
    • Pâques, F.1    Haber, J.E.2
  • 30
    • 84896717088 scopus 로고    scopus 로고
    • Is non-homologous end-Joining really an inherently error-prone process?
    • Bétermier, M., Bertrand, P., and Lopez, B. S. (2014) Is non-homologous end-Joining really an inherently error-prone process? PLoS Genet. 10, e1004086 10.1371/journal.pgen.1004086
    • (2014) PLoS Genet. , vol.10 , pp. e1004086
    • Bétermier, M.1    Bertrand, P.2    Lopez, B.S.3
  • 31
    • 54849404458 scopus 로고    scopus 로고
    • MMEJ repair of double-strand breaks (director's cut): Deleted sequences and alternative endings
    • McVey, M. and Lee, S. E. (2008) MMEJ repair of double-strand breaks (director's cut): deleted sequences and alternative endings Trends Genet. 24, 529-538 10.1016/j.tig.2008.08.007
    • (2008) Trends Genet. , vol.24 , pp. 529-538
    • McVey, M.1    Lee, S.E.2
  • 32
    • 84874773315 scopus 로고    scopus 로고
    • Shuttle vectors for facile gap repair cloning and integration into a neutral locus in Candida albicans
    • Gerami-Nejad, M., Zacchi, L. F., McClellan, M., Matter, K., and Berman, J. (2013) Shuttle vectors for facile gap repair cloning and integration into a neutral locus in Candida albicans Microbiology 159, 565-579 10.1099/mic.0.064097-0
    • (2013) Microbiology , vol.159 , pp. 565-579
    • Gerami-Nejad, M.1    Zacchi, L.F.2    McClellan, M.3    Matter, K.4    Berman, J.5
  • 33
    • 84921392130 scopus 로고    scopus 로고
    • Combinatorial assembly of large biochemical pathways into yeast chromosomes for improved production of value-added compounds
    • Yuan, J. and Ching, C. B. (2014) Combinatorial assembly of large biochemical pathways into yeast chromosomes for improved production of value-added compounds ACS Synth. Biol. 4, 23-31 10.1021/sb500079f
    • (2014) ACS Synth. Biol. , vol.4 , pp. 23-31
    • Yuan, J.1    Ching, C.B.2
  • 34
    • 84885716527 scopus 로고    scopus 로고
    • Continuous co-fermentation of cellobiose and xylose by engineered Saccharomyces cerevisiae
    • Ha, S.-J., Kim, S. R., Kim, H., Du, J., Cate, J. H., and Jin, Y.-S. (2013) Continuous co-fermentation of cellobiose and xylose by engineered Saccharomyces cerevisiae Bioresour. Technol. 149, 525-531 10.1016/j.biortech.2013.09.082
    • (2013) Bioresour. Technol. , vol.149 , pp. 525-531
    • Ha, S.-J.1    Kim, S.R.2    Kim, H.3    Du, J.4    Cate, J.H.5    Jin, Y.-S.6
  • 35
    • 84969504536 scopus 로고    scopus 로고
    • A markerless gene deletion and integration system for Thermoanaerobacter ethanolicus
    • Shao, X., Zhou, J., Olson, D. G., and Lynd, L. R. (2016) A markerless gene deletion and integration system for Thermoanaerobacter ethanolicus Biotechnol. Biofuels 9, 1-8 10.1186/s13068-016-0514-1
    • (2016) Biotechnol. Biofuels , vol.9 , pp. 1-8
    • Shao, X.1    Zhou, J.2    Olson, D.G.3    Lynd, L.R.4
  • 38
    • 84864109921 scopus 로고    scopus 로고
    • New range of vectors with a stringent 5-fluoroorotic acid-based counterselection system for generating mutants by allelic replacement in Staphylococcus aureus
    • Redder, P. and Linder, P. (2012) New range of vectors with a stringent 5-fluoroorotic acid-based counterselection system for generating mutants by allelic replacement in Staphylococcus aureus Appl. Environ. Microbiol. 78, 3846-3854 10.1128/AEM.00202-12
    • (2012) Appl. Environ. Microbiol. , vol.78 , pp. 3846-3854
    • Redder, P.1    Linder, P.2
  • 39
    • 84874778443 scopus 로고    scopus 로고
    • An update on the molecular genetics toolbox for staphylococci
    • Prax, M., Lee, C. Y., and Bertram, R. (2013) An update on the molecular genetics toolbox for staphylococci Microbiology 159, 421-435 10.1099/mic.0.061705-0
    • (2013) Microbiology , vol.159 , pp. 421-435
    • Prax, M.1    Lee, C.Y.2    Bertram, R.3
  • 40
    • 84947279264 scopus 로고    scopus 로고
    • A highly efficient single-step, markerless strategy for multi-copy chromosomal integration of large biochemical pathways in Saccharomyces cerevisiae
    • Shi, S., Liang, Y., Zhang, M. M., Ang, E. L., and Zhao, H. (2016) A highly efficient single-step, markerless strategy for multi-copy chromosomal integration of large biochemical pathways in Saccharomyces cerevisiae Metab. Eng. 33, 19-27 10.1016/j.ymben.2015.10.011
    • (2016) Metab. Eng. , vol.33 , pp. 19-27
    • Shi, S.1    Liang, Y.2    Zhang, M.M.3    Ang, E.L.4    Zhao, H.5
  • 41
    • 84944320385 scopus 로고    scopus 로고
    • The no-SCAR (Scarless Cas9 Assisted Recombineering) system for genome editing in Escherichia coli
    • Reisch, C. R. and Prather, K. L. J. (2015) The no-SCAR (Scarless Cas9 Assisted Recombineering) system for genome editing in Escherichia coli Sci. Rep. 5, 15096 10.1038/srep15096
    • (2015) Sci. Rep. , vol.5 , pp. 15096
    • Reisch, C.R.1    Prather, K.L.J.2
  • 42
    • 84857995434 scopus 로고    scopus 로고
    • Microbial production of indolylglucosinolate through engineering of a multi-gene pathway in a versatile yeast expression platform
    • Mikkelsen, M. D., Buron, L. D., Salomonsen, B., Olsen, C. E., Hansen, B. G., Mortensen, U. H., and Halkier, B. A. (2012) Microbial production of indolylglucosinolate through engineering of a multi-gene pathway in a versatile yeast expression platform Metab. Eng. 14, 104-111 10.1016/j.ymben.2012.01.006
    • (2012) Metab. Eng. , vol.14 , pp. 104-111
    • Mikkelsen, M.D.1    Buron, L.D.2    Salomonsen, B.3    Olsen, C.E.4    Hansen, B.G.5    Mortensen, U.H.6    Halkier, B.A.7
  • 43
    • 70449686525 scopus 로고    scopus 로고
    • Characterization of chromosomal integration sites for heterologous gene expression in Saccharomyces cerevisiae
    • Flagfeldt, D. B., Siewers, V., Huang, L., and Nielsen, J. (2009) Characterization of chromosomal integration sites for heterologous gene expression in Saccharomyces cerevisiae Yeast 26, 545-551 10.1002/yea.1705
    • (2009) Yeast , vol.26 , pp. 545-551
    • Flagfeldt, D.B.1    Siewers, V.2    Huang, L.3    Nielsen, J.4
  • 44
    • 84929572600 scopus 로고    scopus 로고
    • Homology-integrated CRISPR-Cas (HI-CRISPR) system for one-step multigene disruption in Saccharomyces cerevisiae
    • Bao, Z., Xiao, H., Liang, J., Zhang, L., Xiong, X., Sun, N., Si, T., and Zhao, H. (2014) Homology-integrated CRISPR-Cas (HI-CRISPR) system for one-step multigene disruption in Saccharomyces cerevisiae ACS Synth. Biol. 4, 585-594 10.1021/sb500255k
    • (2014) ACS Synth. Biol. , vol.4 , pp. 585-594
    • Bao, Z.1    Xiao, H.2    Liang, J.3    Zhang, L.4    Xiong, X.5    Sun, N.6    Si, T.7    Zhao, H.8
  • 48
    • 84942013003 scopus 로고    scopus 로고
    • A highly characterized yeast toolkit for modular, multipart assembly
    • Lee, M. E., DeLoache, W. C., Cervantes, B., and Dueber, J. E. (2015) A highly characterized yeast toolkit for modular, multipart assembly ACS Synth. Biol. 4, 975-986 10.1021/sb500366v
    • (2015) ACS Synth. Biol. , vol.4 , pp. 975-986
    • Lee, M.E.1    DeLoache, W.C.2    Cervantes, B.3    Dueber, J.E.4
  • 49
    • 84976291148 scopus 로고    scopus 로고
    • Comparison of CRISPR/Cas9 and TALENs on editing an integrated EGFP gene in the genome of HEK293FT cells
    • He, Z., Proudfoot, C., Whitelaw, C. B. A., and Lillico, S. G. (2016) Comparison of CRISPR/Cas9 and TALENs on editing an integrated EGFP gene in the genome of HEK293FT cells SpringerPlus 5, 1-12 10.1186/s40064-016-2536-3
    • (2016) SpringerPlus , vol.5 , pp. 1-12
    • He, Z.1    Proudfoot, C.2    Whitelaw, C.B.A.3    Lillico, S.G.4
  • 50
    • 84936967101 scopus 로고    scopus 로고
    • Coupling the CRISPR/Cas9 system with lambda red recombineering enables simplified chromosomal gene replacement in Escherichia coli
    • Pyne, M. E., Moo-Young, M., Chung, D. A., and Chou, C. P. (2015) Coupling the CRISPR/Cas9 system with lambda red recombineering enables simplified chromosomal gene replacement in Escherichia coli Appl. Environ. Microbiol. 81, 5103-5114 10.1128/AEM.01248-15
    • (2015) Appl. Environ. Microbiol. , vol.81 , pp. 5103-5114
    • Pyne, M.E.1    Moo-Young, M.2    Chung, D.A.3    Chou, C.P.4
  • 51
    • 84937538704 scopus 로고    scopus 로고
    • Metabolic engineering of Escherichia coli using CRISPR-Cas9 meditated genome editing
    • Li, Y., Lin, Z., Huang, C., Zhang, Y., Wang, Z., Tang, Y.-j., Chen, T., and Zhao, X. (2015) Metabolic engineering of Escherichia coli using CRISPR-Cas9 meditated genome editing Metab. Eng. 31, 13-21 10.1016/j.ymben.2015.06.006
    • (2015) Metab. Eng. , vol.31 , pp. 13-21
    • Li, Y.1    Lin, Z.2    Huang, C.3    Zhang, Y.4    Wang, Z.5    Tang, Y.-J.6    Chen, T.7    Zhao, X.8
  • 52
    • 33749037701 scopus 로고    scopus 로고
    • Mechanism of homologous recombination: Mediators and helicases take on regulatory functions
    • Sung, P. and Klein, H. (2006) Mechanism of homologous recombination: mediators and helicases take on regulatory functions Nat. Rev. Mol. Cell Biol. 7, 739-750 10.1038/nrm2008
    • (2006) Nat. Rev. Mol. Cell Biol. , vol.7 , pp. 739-750
    • Sung, P.1    Klein, H.2
  • 53
    • 84880586724 scopus 로고    scopus 로고
    • DNA repair mechanisms in dividing and non-dividing cells
    • Iyama, T. and Wilson, D. M. (2013) DNA repair mechanisms in dividing and non-dividing cells DNA Repair 12, 620-636 10.1016/j.dnarep.2013.04.015
    • (2013) DNA Repair , vol.12 , pp. 620-636
    • Iyama, T.1    Wilson, D.M.2
  • 54
    • 84960124110 scopus 로고    scopus 로고
    • Synthetic biology and molecular genetics in non-conventional yeasts: Current tools and future advances
    • Wagner, J. M. and Alper, H. S. (2016) Synthetic biology and molecular genetics in non-conventional yeasts: current tools and future advances Fungal Genet. Biol. 89, 126-136 10.1016/j.fgb.2015.12.001
    • (2016) Fungal Genet. Biol. , vol.89 , pp. 126-136
    • Wagner, J.M.1    Alper, H.S.2
  • 55
    • 84863090270 scopus 로고    scopus 로고
    • Deletion of the Pichia pastoris KU70 homologue facilitates platform strain generation for gene expression and synthetic biology
    • Näätsaari, L., Mistlberger, B., Ruth, C., Hajek, T., Hartner, F. S., and Glieder, A. (2012) Deletion of the Pichia pastoris KU70 homologue facilitates platform strain generation for gene expression and synthetic biology PLoS One 7, e39720 10.1371/journal.pone.0039720
    • (2012) PLoS One , vol.7 , pp. e39720
    • Näätsaari, L.1    Mistlberger, B.2    Ruth, C.3    Hajek, T.4    Hartner, F.S.5    Glieder, A.6
  • 57
    • 84874802005 scopus 로고    scopus 로고
    • Efficient homologous recombination with short length flanking fragments in Ku70 deficient Yarrowia lipolytica strains
    • Verbeke, J., Beopoulos, A., and Nicaud, J.-M. (2013) Efficient homologous recombination with short length flanking fragments in Ku70 deficient Yarrowia lipolytica strains Biotechnol. Lett. 35, 571-576 10.1007/s10529-012-1107-0
    • (2013) Biotechnol. Lett. , vol.35 , pp. 571-576
    • Verbeke, J.1    Beopoulos, A.2    Nicaud, J.-M.3
  • 58
    • 84929147435 scopus 로고    scopus 로고
    • Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells
    • Chu, V. T., Weber, T., Wefers, B., Wurst, W., Sander, S., Rajewsky, K., and Kühn, R. (2015) Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells Nat. Biotechnol. 33, 543-548 10.1038/nbt.3198
    • (2015) Nat. Biotechnol. , vol.33 , pp. 543-548
    • Chu, V.T.1    Weber, T.2    Wefers, B.3    Wurst, W.4    Sander, S.5    Rajewsky, K.6    Kühn, R.7
  • 59
    • 84892840633 scopus 로고    scopus 로고
    • Harnessing Yarrowia lipolytica lipogenesis to create a platform for lipid and biofuel production
    • Blazeck, J., Hill, A., Liu, L., Knight, R., Miller, J., Pan, A., Otoupal, P., and Alper, H. S. (2014) Harnessing Yarrowia lipolytica lipogenesis to create a platform for lipid and biofuel production Nat. Commun. 5, 3131 10.1038/ncomms4131
    • (2014) Nat. Commun. , vol.5 , pp. 3131
    • Blazeck, J.1    Hill, A.2    Liu, L.3    Knight, R.4    Miller, J.5    Pan, A.6    Otoupal, P.7    Alper, H.S.8
  • 60
    • 84907459051 scopus 로고    scopus 로고
    • Analysis of the role of homology arms in gene-targeting vectors in human cells
    • Ishii, A., Kurosawa, A., Saito, S., and Adachi, N. (2014) Analysis of the role of homology arms in gene-targeting vectors in human cells PLoS One 9, e108236 10.1371/journal.pone.0108236
    • (2014) PLoS One , vol.9 , pp. e108236
    • Ishii, A.1    Kurosawa, A.2    Saito, S.3    Adachi, N.4
  • 61
    • 84960911917 scopus 로고    scopus 로고
    • Enhancing homology-directed genome editing by catalytically active and inactive CRISPR-Cas9 using asymmetric donor DNA
    • Richardson, C. D., Ray, G. J., DeWitt, M. A., Curie, G. L., and Corn, J. E. (2016) Enhancing homology-directed genome editing by catalytically active and inactive CRISPR-Cas9 using asymmetric donor DNA Nat. Biotechnol. 34, 339-344 10.1038/nbt.3481
    • (2016) Nat. Biotechnol. , vol.34 , pp. 339-344
    • Richardson, C.D.1    Ray, G.J.2    DeWitt, M.A.3    Curie, G.L.4    Corn, J.E.5
  • 63
    • 84961334208 scopus 로고    scopus 로고
    • RS-1 enhances CRISPR/Cas9- and TALEN-mediated knock-in efficiency
    • Song, J., Yang, D., Xu, J., Zhu, T., Chen, Y. E., and Zhang, J. (2016) RS-1 enhances CRISPR/Cas9- and TALEN-mediated knock-in efficiency Nat. Commun. 7, 10548 10.1038/ncomms10548
    • (2016) Nat. Commun. , vol.7 , pp. 10548
    • Song, J.1    Yang, D.2    Xu, J.3    Zhu, T.4    Chen, Y.E.5    Zhang, J.6
  • 64
    • 35848960148 scopus 로고    scopus 로고
    • Nonhomologous end-joining in bacteria: A microbial perspective
    • Pitcher, R. S., Brissett, N. C., and Doherty, A. J. (2007) Nonhomologous end-joining in bacteria: a microbial perspective Annu. Rev. Microbiol. 61, 259-82 10.1146/annurev.micro.61.080706.093354
    • (2007) Annu. Rev. Microbiol. , vol.61 , pp. 259-282
    • Pitcher, R.S.1    Brissett, N.C.2    Doherty, A.J.3
  • 65
    • 84966344968 scopus 로고    scopus 로고
    • In vivo blunt-end cloning through CRISPR/Cas9-facilitated non-homologous end-joining
    • Geisinger, J. M., Turan, S., Hernandez, S., Spector, L. P., and Calos, M. P. (2016) In vivo blunt-end cloning through CRISPR/Cas9-facilitated non-homologous end-joining Nucleic Acids Res. 44, e76 10.1093/nar/gkv1542
    • (2016) Nucleic Acids Res. , vol.44 , pp. e76
    • Geisinger, J.M.1    Turan, S.2    Hernandez, S.3    Spector, L.P.4    Calos, M.P.5
  • 68
    • 84969963103 scopus 로고    scopus 로고
    • Knock-in of large reporter genes in human cells via CRISPR/Cas9-induced homology-dependent and independent DNA repair
    • He, X., Tan, C., Wang, F., Wang, Y., Zhou, R., Cui, D., You, W., Zhao, H., Ren, J., and Feng, B. (2016) Knock-in of large reporter genes in human cells via CRISPR/Cas9-induced homology-dependent and independent DNA repair Nucleic Acids Res. 44, e85 10.1093/nar/gkw064
    • (2016) Nucleic Acids Res. , vol.44 , pp. e85
    • He, X.1    Tan, C.2    Wang, F.3    Wang, Y.4    Zhou, R.5    Cui, D.6    You, W.7    Zhao, H.8    Ren, J.9    Feng, B.10
  • 69
    • 84874613680 scopus 로고    scopus 로고
    • Obligate ligation-gated recombination (ObLiGaRe): Custom-designed nuclease-mediated targeted integration through nonhomologous end joining
    • Maresca, M., Lin, V. G., Guo, N., and Yang, Y. (2013) Obligate ligation-gated recombination (ObLiGaRe): custom-designed nuclease-mediated targeted integration through nonhomologous end joining Genome Res. 23, 539-546 10.1101/gr.145441.112
    • (2013) Genome Res. , vol.23 , pp. 539-546
    • Maresca, M.1    Lin, V.G.2    Guo, N.3    Yang, Y.4
  • 70
    • 84960245297 scopus 로고    scopus 로고
    • Heritable CRISPR/Cas9-mediated targeted integration in Xenopus tropicalis
    • Shi, Z., Wang, F., Cui, Y., Liu, Z., Guo, X., Zhang, Y., Deng, Y., Zhao, H., and Chen, Y. (2015) Heritable CRISPR/Cas9-mediated targeted integration in Xenopus tropicalis FASEB J. 29, 4914-4923 10.1096/fj.15-273425
    • (2015) FASEB J. , vol.29 , pp. 4914-4923
    • Shi, Z.1    Wang, F.2    Cui, Y.3    Liu, Z.4    Guo, X.5    Zhang, Y.6    Deng, Y.7    Zhao, H.8    Chen, Y.9
  • 71
    • 84962866438 scopus 로고    scopus 로고
    • Systematic quantification of HDR and NHEJ reveals effects of locus, nuclease, and cell type on genome-editing
    • Miyaoka, Y., Berman, J. R., Cooper, S. B., Mayerl, S. J., Chan, A. H., Zhang, B., Karlin-Neumann, G. A., and Conklin, B. R. (2016) Systematic quantification of HDR and NHEJ reveals effects of locus, nuclease, and cell type on genome-editing Sci. Rep. 6, 23549 10.1038/srep23549
    • (2016) Sci. Rep. , vol.6 , pp. 23549
    • Miyaoka, Y.1    Berman, J.R.2    Cooper, S.B.3    Mayerl, S.J.4    Chan, A.H.5    Zhang, B.6    Karlin-Neumann, G.A.7    Conklin, B.R.8
  • 72
    • 33745085925 scopus 로고    scopus 로고
    • Short hairpin RNA-expressing bacteria elicit RNA interference in mammals
    • Xiang, S., Fruehauf, J., and Li, C. J. (2006) Short hairpin RNA-expressing bacteria elicit RNA interference in mammals Nat. Biotechnol. 24, 697-702 10.1038/nbt1211
    • (2006) Nat. Biotechnol. , vol.24 , pp. 697-702
    • Xiang, S.1    Fruehauf, J.2    Li, C.J.3
  • 73
    • 84877321963 scopus 로고    scopus 로고
    • Microhomology-mediated end Joining and homologous recombination share the initial end resection step to repair DNA double-strand breaks in mammalian cells
    • Truong, L. N., Li, Y., Shi, L. Z., Hwang, P. Y., He, J., Wang, H., Razavian, N., Berns, M. W., and Wu, X. (2013) Microhomology-mediated end Joining and homologous recombination share the initial end resection step to repair DNA double-strand breaks in mammalian cells Proc. Natl. Acad. Sci. U. S. A. 110, 7720-7725 10.1073/pnas.1213431110
    • (2013) Proc. Natl. Acad. Sci. U. S. A. , vol.110 , pp. 7720-7725
    • Truong, L.N.1    Li, Y.2    Shi, L.Z.3    Hwang, P.Y.4    He, J.5    Wang, H.6    Razavian, N.7    Berns, M.W.8    Wu, X.9
  • 74
    • 84924365995 scopus 로고    scopus 로고
    • Precise in-frame integration of exogenous DNA mediated by CRISPR/Cas9 system in zebrafish
    • Hisano, Y., Sakuma, T., Nakade, S., Ohga, R., Ota, S., Okamoto, H., Yamamoto, T., and Kawahara, A. (2015) Precise in-frame integration of exogenous DNA mediated by CRISPR/Cas9 system in zebrafish Sci. Rep. 5, 8841 10.1038/srep08841
    • (2015) Sci. Rep. , vol.5 , pp. 8841
    • Hisano, Y.1    Sakuma, T.2    Nakade, S.3    Ohga, R.4    Ota, S.5    Okamoto, H.6    Yamamoto, T.7    Kawahara, A.8
  • 75
    • 84944096861 scopus 로고    scopus 로고
    • Homologous recombination-independent large gene cassette knock-in in CHO cells using TALEN and MMEJ-directed donor plasmids
    • Sakuma, T., Takenaga, M., Kawabe, Y., Nakamura, T., Kamihira, M., and Yamamoto, T. (2015) Homologous recombination-independent large gene cassette knock-in in CHO cells using TALEN and MMEJ-directed donor plasmids Int. J. Mol. Sci. 16, 23849-23866 10.3390/ijms161023849
    • (2015) Int. J. Mol. Sci. , vol.16 , pp. 23849-23866
    • Sakuma, T.1    Takenaga, M.2    Kawabe, Y.3    Nakamura, T.4    Kamihira, M.5    Yamamoto, T.6
  • 76
    • 84903217296 scopus 로고    scopus 로고
    • Multiplex genome engineering in human cells using all-in-one CRISPR/Cas9 vector system
    • Sakuma, T., Nishikawa, A., Kume, S., Chayama, K., and Yamamoto, T. (2014) Multiplex genome engineering in human cells using all-in-one CRISPR/Cas9 vector system Sci. Rep. 4, 5400 10.1038/srep05400
    • (2014) Sci. Rep. , vol.4 , pp. 5400
    • Sakuma, T.1    Nishikawa, A.2    Kume, S.3    Chayama, K.4    Yamamoto, T.5
  • 78
    • 84950264293 scopus 로고    scopus 로고
    • Highly efficient CRISPR mutagenesis by microhomology-mediated end joining in Aspergillus fumigatus
    • Zhang, C., Meng, X., Wei, X., and Lu, L. (2016) Highly efficient CRISPR mutagenesis by microhomology-mediated end joining in Aspergillus fumigatus Fungal Genet. Biol. 86, 47-57 10.1016/j.fgb.2015.12.007
    • (2016) Fungal Genet. Biol. , vol.86 , pp. 47-57
    • Zhang, C.1    Meng, X.2    Wei, X.3    Lu, L.4
  • 79
    • 84940827347 scopus 로고    scopus 로고
    • CRISPR-Cas9-mediated genome editing in Leishmania donovani
    • Zhang, W. W. and Matlashewski, G. (2015) CRISPR-Cas9-mediated genome editing in Leishmania donovani mBio 6, e00861 10.1128/mBio.00861-15
    • (2015) MBio , vol.6 , pp. e00861
    • Zhang, W.W.1    Matlashewski, G.2
  • 80
    • 84940032369 scopus 로고    scopus 로고
    • Efficient ligase 3-dependent microhomology-mediated end joining repair of DNA double-strand breaks in zebrafish embryos
    • He, M. D., Zhang, F. H., Wang, H. L., Wang, H. P., Zhu, Z. Y., and Sun, Y. H. (2015) Efficient ligase 3-dependent microhomology-mediated end joining repair of DNA double-strand breaks in zebrafish embryos Mutat. Res., Fundam. Mol. Mech. Mutagen. 780, 86-96 10.1016/j.mrfmmm.2015.08.004
    • (2015) Mutat. Res., Fundam. Mol. Mech. Mutagen. , vol.780 , pp. 86-96
    • He, M.D.1    Zhang, F.H.2    Wang, H.L.3    Wang, H.P.4    Zhu, Z.Y.5    Sun, Y.H.6
  • 81
    • 77950521498 scopus 로고    scopus 로고
    • Zinc-finger nuclease-induced gene repair with oligodeoxynucleotides: Wanted and unwanted target locus modifications
    • Radecke, S., Radecke, F., Cathomen, T., and Schwarz, K. (2010) Zinc-finger nuclease-induced gene repair with oligodeoxynucleotides: wanted and unwanted target locus modifications Mol. Ther. 18, 743-753 10.1038/mt.2009.304
    • (2010) Mol. Ther. , vol.18 , pp. 743-753
    • Radecke, S.1    Radecke, F.2    Cathomen, T.3    Schwarz, K.4
  • 82
    • 44449089576 scopus 로고    scopus 로고
    • Double-stranded break can be repaired by single-stranded oligonucleotides via the ATM/ATR pathway in mammalian cells
    • Wang, Z., Zhou, Z.-J., Liu, D.-P., and Huang, J.-D. (2008) Double-stranded break can be repaired by single-stranded oligonucleotides via the ATM/ATR pathway in mammalian cells Oligonucleotides 18, 21-32 10.1089/oli.2007.0093
    • (2008) Oligonucleotides , vol.18 , pp. 21-32
    • Wang, Z.1    Zhou, Z.-J.2    Liu, D.-P.3    Huang, J.-D.4
  • 83
    • 32844470294 scopus 로고    scopus 로고
    • Physical incorporation of a single-stranded oligodeoxynucleotide during targeted repair of a human chromosomal locus
    • Radecke, S., Radecke, F., Peter, I., and Schwarz, K. (2006) Physical incorporation of a single-stranded oligodeoxynucleotide during targeted repair of a human chromosomal locus J. Gene Med. 8, 217-228 10.1002/jgm.828
    • (2006) J. Gene Med. , vol.8 , pp. 217-228
    • Radecke, S.1    Radecke, F.2    Peter, I.3    Schwarz, K.4
  • 85
    • 84886067459 scopus 로고    scopus 로고
    • Efficient knockin mouse generation by ssDNA oligonucleotides and zinc-Finger nuclease assisted homologous recombination in zygotes
    • Shen, B., Zhang, X., Du, Y., Wang, J., Gong, J., Zhang, X., Tate, P. H., Li, H., Huang, X., and Zhang, W. (2013) Efficient knockin mouse generation by ssDNA oligonucleotides and zinc-Finger nuclease assisted homologous recombination in zygotes PLoS One 8, e77696 10.1371/journal.pone.0077696
    • (2013) PLoS One , vol.8 , pp. e77696
    • Shen, B.1    Zhang, X.2    Du, Y.3    Wang, J.4    Gong, J.5    Zhang, X.6    Tate, P.H.7    Li, H.8    Huang, X.9    Zhang, W.10
  • 86
    • 84955569113 scopus 로고    scopus 로고
    • SsODN-mediated knock-in with CRISPR-Cas for large genomic regions in zygotes
    • Yoshimi, K., Kunihiro, Y., Kaneko, T., Nagahora, H., Voigt, B., and Mashimo, T. (2016) ssODN-mediated knock-in with CRISPR-Cas for large genomic regions in zygotes Nat. Commun. 7, 10431 10.1038/ncomms10431
    • (2016) Nat. Commun. , vol.7 , pp. 10431
    • Yoshimi, K.1    Kunihiro, Y.2    Kaneko, T.3    Nagahora, H.4    Voigt, B.5    Mashimo, T.6
  • 87
    • 84938922797 scopus 로고    scopus 로고
    • CRISPR/Cas9-based generation of knockdown mice by intronic insertion of artificial microRNA using longer single-stranded DNA
    • Miura, H., Gurumurthy, C. B., Sato, T., Sato, M., and Ohtsuka, M. (2015) CRISPR/Cas9-based generation of knockdown mice by intronic insertion of artificial microRNA using longer single-stranded DNA Sci. Rep. 5, 12799 10.1038/srep12799
    • (2015) Sci. Rep. , vol.5 , pp. 12799
    • Miura, H.1    Gurumurthy, C.B.2    Sato, T.3    Sato, M.4    Ohtsuka, M.5
  • 88
    • 78951480559 scopus 로고    scopus 로고
    • Lambda red recombineering in Escherichia coli occurs through a fully single-stranded intermediate
    • Mosberg, J. A., Lajoie, M. J., and Church, G. M. (2010) Lambda red recombineering in Escherichia coli occurs through a fully single-stranded intermediate Genetics 186, 791-799 10.1534/genetics.110.120782
    • (2010) Genetics , vol.186 , pp. 791-799
    • Mosberg, J.A.1    Lajoie, M.J.2    Church, G.M.3
  • 89
    • 84874608929 scopus 로고    scopus 로고
    • RNA-guided editing of bacterial genomes using CRISPR-Cas systems
    • Jiang, W., Bikard, D., Cox, D., Zhang, F., and Marraffini, L. A. (2013) RNA-guided editing of bacterial genomes using CRISPR-Cas systems Nat. Biotechnol. 31, 233-239 10.1038/nbt.2508
    • (2013) Nat. Biotechnol. , vol.31 , pp. 233-239
    • Jiang, W.1    Bikard, D.2    Cox, D.3    Zhang, F.4    Marraffini, L.A.5
  • 90
    • 79960322274 scopus 로고    scopus 로고
    • A place for everything: Chromosomal integration of large constructs
    • Kuhlman, T. E. and Cox, E. C. (2010) A place for everything: chromosomal integration of large constructs Bioeng. Bugs 1, 298-301 10.4161/bbug.1.4.12386
    • (2010) Bioeng. Bugs , vol.1 , pp. 298-301
    • Kuhlman, T.E.1    Cox, E.C.2
  • 91
    • 0033676098 scopus 로고    scopus 로고
    • DNA cloning using in vitro site-specific recombination
    • Hartley, J. L., Temple, G. F., and Brasch, M. A. (2000) DNA cloning using in vitro site-specific recombination Genome Res. 10, 1788-1795 10.1101/gr.143000
    • (2000) Genome Res. , vol.10 , pp. 1788-1795
    • Hartley, J.L.1    Temple, G.F.2    Brasch, M.A.3
  • 92
    • 84957564999 scopus 로고    scopus 로고
    • Comparison and optimization of ten phage encoded serine integrases for genome engineering in Saccharomyces cerevisiae
    • Xu, Z. and Brown, W. R. (2016) Comparison and optimization of ten phage encoded serine integrases for genome engineering in Saccharomyces cerevisiae BMC Biotechnol. 16, 1 10.1186/s12896-016-0241-5
    • (2016) BMC Biotechnol. , vol.16 , pp. 1
    • Xu, Z.1    Brown, W.R.2
  • 93
    • 85013155314 scopus 로고    scopus 로고
    • A programmable Cas9-serine recombinase fusion protein that operates on DNA sequences in mammalian cells
    • Chaikind, B., Bessen, J. L., Thompson, D. B., Hu, J. H., and Liu, D. R. (2016) A programmable Cas9-serine recombinase fusion protein that operates on DNA sequences in mammalian cells Nucleic Acids Res. gkw707 10.1093/nar/gkw707
    • (2016) Nucleic Acids Res. , pp. gkw707
    • Chaikind, B.1    Bessen, J.L.2    Thompson, D.B.3    Hu, J.H.4    Liu, D.R.5
  • 94
    • 84899027573 scopus 로고    scopus 로고
    • Expanding the zinc-finger recombinase repertoire: Directed evolution and mutational analysis of serine recombinase specificity determinants
    • Sirk, S. J., Gaj, T., Jonsson, A., Mercer, A. C., and Barbas, C. F. (2014) Expanding the zinc-finger recombinase repertoire: directed evolution and mutational analysis of serine recombinase specificity determinants Nucleic Acids Res. 42, 4755-4766 10.1093/nar/gkt1389
    • (2014) Nucleic Acids Res. , vol.42 , pp. 4755-4766
    • Sirk, S.J.1    Gaj, T.2    Jonsson, A.3    Mercer, A.C.4    Barbas, C.F.5
  • 95
    • 84870579235 scopus 로고    scopus 로고
    • Chimeric TALE recombinases with programmable DNA sequence specificity
    • Mercer, A. C., Gaj, T., Fuller, R. P., and Barbas, C. F. (2012) Chimeric TALE recombinases with programmable DNA sequence specificity Nucleic Acids Res. 40, 11163-11172 10.1093/nar/gks875
    • (2012) Nucleic Acids Res. , vol.40 , pp. 11163-11172
    • Mercer, A.C.1    Gaj, T.2    Fuller, R.P.3    Barbas, C.F.4
  • 98
    • 84867645703 scopus 로고    scopus 로고
    • Exploring DNA assembler, a synthetic biology tool for characterizing and engineering natural product gene clusters
    • Shao, Z. and Zhao, H. (2012) Exploring DNA assembler, a synthetic biology tool for characterizing and engineering natural product gene clusters Methods Enzymol. 517, 203 10.1016/B978-0-12-404634-4.00010-3
    • (2012) Methods Enzymol. , vol.517 , pp. 203
    • Shao, Z.1    Zhao, H.2
  • 102
    • 84866850621 scopus 로고    scopus 로고
    • Development of novel visual-plus quantitative analysis systems for studying DNA souble-strand break repairs in zebrafish
    • Liu, J., Gong, L., Chang, C., Liu, C., Peng, J., and Chen, J. (2012) Development of novel visual-plus quantitative analysis systems for studying DNA souble-strand break repairs in zebrafish J. Genet. Genomics 39, 489-502 10.1016/j.jgg.2012.07.009
    • (2012) J. Genet. Genomics , vol.39 , pp. 489-502
    • Liu, J.1    Gong, L.2    Chang, C.3    Liu, C.4    Peng, J.5    Chen, J.6
  • 103
    • 84963795110 scopus 로고    scopus 로고
    • Assays for DNA double-strand break repair by microhomology-based end-joining repair mechanisms
    • Kostyrko, K. and Mermod, N. (2016) Assays for DNA double-strand break repair by microhomology-based end-joining repair mechanisms Nucleic Acids Res. 44, e56 10.1093/nar/gkv1349
    • (2016) Nucleic Acids Res. , vol.44 , pp. e56
    • Kostyrko, K.1    Mermod, N.2
  • 104
    • 84934947770 scopus 로고    scopus 로고
    • High-efficiency multiplex genome editing of Streptomyces species using an engineered CRISPR/Cas system
    • Cobb, R. E., Wang, Y., and Zhao, H. (2015) High-efficiency multiplex genome editing of Streptomyces species using an engineered CRISPR/Cas system ACS Synth. Biol. 4, 723-8 10.1021/sb500351f
    • (2015) ACS Synth. Biol. , vol.4 , pp. 723-728
    • Cobb, R.E.1    Wang, Y.2    Zhao, H.3
  • 105
    • 84927695100 scopus 로고    scopus 로고
    • Genome engineering with CRISPR-Cas9 in the mosquito Aedes aegypti
    • Kistler, K. E., Vosshall, L. B., and Matthews, B. J. (2015) Genome engineering with CRISPR-Cas9 in the mosquito Aedes aegypti Cell Rep. 11, 51-60 10.1016/j.celrep.2015.03.009
    • (2015) Cell Rep. , vol.11 , pp. 51-60
    • Kistler, K.E.1    Vosshall, L.B.2    Matthews, B.J.3
  • 106
    • 84890787845 scopus 로고    scopus 로고
    • Simple and efficient CRISPR/Cas9-mediated targeted mutagenesis in Xenopus tropicalis
    • Nakayama, T., Fish, M. B., Fisher, M., Oomen-Hajagos, J., Thomsen, G. H., and Grainger, R. M. (2013) Simple and efficient CRISPR/Cas9-mediated targeted mutagenesis in Xenopus tropicalis Genesis 51, 835-43 10.1002/dvg.22720
    • (2013) Genesis , vol.51 , pp. 835-843
    • Nakayama, T.1    Fish, M.B.2    Fisher, M.3    Oomen-Hajagos, J.4    Thomsen, G.H.5    Grainger, R.M.6
  • 107
    • 84941358492 scopus 로고    scopus 로고
    • Efficient genome editing in filamentous fungus Trichoderma reesei using the CRISPR/Cas9 system
    • Liu, R., Chen, L., Jiang, Y., Zhou, Z., and Zou, G. (2015) Efficient genome editing in filamentous fungus Trichoderma reesei using the CRISPR/Cas9 system Cell Discovery 1, 15007 10.1038/celldisc.2015.7
    • (2015) Cell Discovery , vol.1 , pp. 15007
    • Liu, R.1    Chen, L.2    Jiang, Y.3    Zhou, Z.4    Zou, G.5
  • 108
    • 84929084104 scopus 로고    scopus 로고
    • Mammoth genomes hold recipe for Arctic elephants
    • Callaway, E. (2015) Mammoth genomes hold recipe for Arctic elephants Nature 521, 18-9 10.1038/nature.2015.17462
    • (2015) Nature , vol.521 , pp. 18-19
    • Callaway, E.1
  • 109
    • 59649108349 scopus 로고    scopus 로고
    • DNA assembler, an in vivo genetic method for rapid construction of biochemical pathways
    • Shao, Z., Zhao, H., and Zhao, H. (2009) DNA assembler, an in vivo genetic method for rapid construction of biochemical pathways Nucleic Acids Res. 37, e16 10.1093/nar/gkn991
    • (2009) Nucleic Acids Res. , vol.37 , pp. e16
    • Shao, Z.1    Zhao, H.2    Zhao, H.3
  • 110
    • 0035462342 scopus 로고    scopus 로고
    • Efficient system for directed integration into the Lactobacillus acidophilus and Lactobacillus gasseri chromosomes via homologous recombination
    • Russell, W. and Klaenhammer, T. (2001) Efficient system for directed integration into the Lactobacillus acidophilus and Lactobacillus gasseri chromosomes via homologous recombination Appl. Environ. Microbiol. 67, 4361-4364 10.1128/AEM.67.9.4361-4364.2001
    • (2001) Appl. Environ. Microbiol. , vol.67 , pp. 4361-4364
    • Russell, W.1    Klaenhammer, T.2
  • 111
    • 0030724364 scopus 로고    scopus 로고
    • Improvement of Bacillus sphaericus toxicity against dipteran larvae by integration, via homologous recombination, of the Cry11A toxin gene from Bacillus thuringiensis subsp. Israelensis
    • Poncet, S., Bernard, C., Dervyn, E., Cayley, J., Klier, A., and Rapoport, G. (1997) Improvement of Bacillus sphaericus toxicity against dipteran larvae by integration, via homologous recombination, of the Cry11A toxin gene from Bacillus thuringiensis subsp. israelensis Appl. Environ. Microbiol. 63, 4413-4420
    • (1997) Appl. Environ. Microbiol. , vol.63 , pp. 4413-4420
    • Poncet, S.1    Bernard, C.2    Dervyn, E.3    Cayley, J.4    Klier, A.5    Rapoport, G.6
  • 113
    • 0029022709 scopus 로고
    • Homologous recombination as the main mechanism for DNA integration and cause of rearrangements in the filamentous ascomycete Ashbya gossypii
    • Steiner, S., Wendland, J., Wright, M. C., and Philippsen, P. (1995) Homologous recombination as the main mechanism for DNA integration and cause of rearrangements in the filamentous ascomycete Ashbya gossypii Genetics 140, 973-987
    • (1995) Genetics , vol.140 , pp. 973-987
    • Steiner, S.1    Wendland, J.2    Wright, M.C.3    Philippsen, P.4
  • 114
    • 0027957822 scopus 로고
    • Integration of vectors by homologous recombination in the plant pathogen Glomerella cingulata
    • Rikkerink, E. H., Solon, S. L., Crowhurst, R. N., and Templeton, M. D. (1994) Integration of vectors by homologous recombination in the plant pathogen Glomerella cingulata Curr. Genet. 25, 202-208 10.1007/BF00357163
    • (1994) Curr. Genet. , vol.25 , pp. 202-208
    • Rikkerink, E.H.1    Solon, S.L.2    Crowhurst, R.N.3    Templeton, M.D.4
  • 115
    • 33845653228 scopus 로고    scopus 로고
    • The mechanism of gene targeting in Physcomitrella patens: Homologous recombination, concatenation and multiple integration
    • Kamisugi, Y., Schlink, K., Rensing, S. A., Schween, G., von Stackelberg, M., Cuming, A. C., Reski, R., and Cove, D. J. (2006) The mechanism of gene targeting in Physcomitrella patens: homologous recombination, concatenation and multiple integration Nucleic Acids Res. 34, 6205-6214 10.1093/nar/gkl832
    • (2006) Nucleic Acids Res. , vol.34 , pp. 6205-6214
    • Kamisugi, Y.1    Schlink, K.2    Rensing, S.A.3    Schween, G.4    Von Stackelberg, M.5    Cuming, A.C.6    Reski, R.7    Cove, D.J.8
  • 116
    • 84903516238 scopus 로고    scopus 로고
    • Microhomology-based choice of Cas9 nuclease target sites
    • Bae, S., Kweon, J., Kim, H. S., and Kim, J.-S. (2014) Microhomology-based choice of Cas9 nuclease target sites Nat. Methods 11, 705-706 10.1038/nmeth.3015
    • (2014) Nat. Methods , vol.11 , pp. 705-706
    • Bae, S.1    Kweon, J.2    Kim, H.S.3    Kim, J.-S.4
  • 117
    • 84978665442 scopus 로고    scopus 로고
    • Multiplexed targeted genome engineering using a universal nuclease-assisted vector integration system
    • Brown, A., Woods, W. S., and Perez-Pinera, P. (2016) Multiplexed targeted genome engineering using a universal nuclease-assisted vector integration system ACS Synth. Biol. 5, 582-588 10.1021/acssynbio.6b00056
    • (2016) ACS Synth. Biol. , vol.5 , pp. 582-588
    • Brown, A.1    Woods, W.S.2    Perez-Pinera, P.3
  • 119
    • 84903555108 scopus 로고    scopus 로고
    • Allele-specific genome editing and correction of disease-associated phenotypes in rats using the CRISPR-Cas platform
    • Yoshimi, K., Kaneko, T., Voigt, B., and Mashimo, T. (2014) Allele-specific genome editing and correction of disease-associated phenotypes in rats using the CRISPR-Cas platform Nat. Commun. 5, 4240 10.1038/ncomms5240
    • (2014) Nat. Commun. , vol.5 , pp. 4240
    • Yoshimi, K.1    Kaneko, T.2    Voigt, B.3    Mashimo, T.4
  • 120
    • 84862184780 scopus 로고    scopus 로고
    • Modeling disease mutations by gene targeting in one-cell mouse embryos
    • Meyer, M., Ortiz, O., de Angelis, M. H., Wurst, W., and Kühn, R. (2012) Modeling disease mutations by gene targeting in one-cell mouse embryos Proc. Natl. Acad. Sci. U. S. A. 109, 9354-9359 10.1073/pnas.1121203109
    • (2012) Proc. Natl. Acad. Sci. U. S. A. , vol.109 , pp. 9354-9359
    • Meyer, M.1    Ortiz, O.2    De Angelis, M.H.3    Wurst, W.4    Kühn, R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.