SsODN-mediated knock-in with CRISPR-Cas for large genomic regions in zygotes

Nature Communications

Volumn 7, Issue , 2016, Pages

  Yoshimi, Kazuto ^a,b   Kunihiro, Yayoi ^a,c   Kaneko, Takehito ^a   Nagahora, Hitoshi ^d   Voigt, Birger ^a   Mashimo, Tomoji ^a,c  

^a KYOTO UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE OF GENETICS   (Japan)

^c OSAKA UNIVERSITY   (Japan)

^d BioDynamics Laboratory Inc   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 2D6; GUIDE RNA; MESSENGER RNA; OLIGODEOXYNUCLEOTIDE; DIFFERENTIATION ANTIGEN; IMMUNOGLOBULIN RECEPTOR; OLIGODEOXYRIBONUCLEOTIDE; SIRPA PROTEIN, HUMAN;

GENE EXPRESSION; GENETIC ENGINEERING; GENOMICS; HUMAN EVOLUTION; RNA; RODENT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BACTERIAL ARTIFICIAL CHROMOSOME; CONTROLLED STUDY; CRISPR CAS SYSTEM; GENE; GENE CLUSTER; GENE LOCUS; GENE VECTOR; GENETIC ENGINEERING; HOMOLOGOUS RECOMBINATION; NONHUMAN; RAT; ZYGOTE; ANIMAL; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; FEMALE; GENE TARGETING; GENETICS; HUMAN; MALE; METABOLISM; MOUSE; PROCEDURES;

ANIMALIA; RATTUS;

ANIMALS; ANTIGENS, DIFFERENTIATION; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS; CRISPR-CAS SYSTEMS; FEMALE; GENE KNOCK-IN TECHNIQUES; GENETIC ENGINEERING; HOMOLOGOUS RECOMBINATION; HUMANS; MALE; MICE; OLIGODEOXYRIBONUCLEOTIDES; RATS; RECEPTORS, IMMUNOLOGIC; ZYGOTE;

EID: 84955569113     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms10431     Document Type: Article

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