-
1
-
-
84902185906
-
Genome engineering with targetable nucleases
-
Carroll, D. Genome engineering with targetable nucleases. Annu. Rev. Biochem. 83, 409-439 (2014).
-
(2014)
Annu. Rev. Biochem
, vol.83
, pp. 409-439
-
-
Carroll, D.1
-
2
-
-
84898778301
-
A guide to genome engineering with programmable nucleases
-
Kim, H. & Kim, J. S. A guide to genome engineering with programmable nucleases. Nat. Rev. Genet. 15, 321-334 (2014).
-
(2014)
Nat. Rev. Genet
, vol.15
, pp. 321-334
-
-
Kim, H.1
Kim, J.S.2
-
3
-
-
80052292973
-
High-frequency genome editing using ssDNA oligonucleotides with zinc-finger nucleases
-
Chen, F. et al. High-frequency genome editing using ssDNA oligonucleotides with zinc-finger nucleases. Nat. Methods 8, 753-755 (2011).
-
(2011)
Nat. Methods
, vol.8
, pp. 753-755
-
-
Chen, F.1
-
4
-
-
84895528015
-
Isolation of single-base genome-edited human iPS cells without antibiotic selection
-
Miyaoka, Y. et al. Isolation of single-base genome-edited human iPS cells without antibiotic selection. Nat. Methods 11, 291-293 (2014).
-
(2014)
Nat. Methods
, vol.11
, pp. 291-293
-
-
Miyaoka, Y.1
-
5
-
-
70249114821
-
Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases
-
Hockemeyer, D. et al. Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases. Nat. Biotechnol. 27, 851-857 (2009).
-
(2009)
Nat. Biotechnol
, vol.27
, pp. 851-857
-
-
Hockemeyer, D.1
-
6
-
-
79960836456
-
Genetic engineering of human pluripotent cells using TALE nucleases
-
Hockemeyer, D. et al. Genetic engineering of human pluripotent cells using TALE nucleases. Nat. Biotechnol. 29, 731-734 (2011).
-
(2011)
Nat. Biotechnol
, vol.29
, pp. 731-734
-
-
Hockemeyer, D.1
-
7
-
-
77955126358
-
Zinc-finger nuclease-driven targeted integration into mammalian genomes using donors with limited chromosomal homology
-
Orlando, S. J. et al. Zinc-finger nuclease-driven targeted integration into mammalian genomes using donors with limited chromosomal homology. Nucleic Acids Res. 38, e152 (2010).
-
(2010)
Nucleic Acids Res
, vol.38
, pp. 152
-
-
Orlando, S.J.1
-
8
-
-
84872669342
-
Vivo cleavage of transgene donors promotes nucleasemediated targeted integration
-
Cristea, S. et al. In vivo cleavage of transgene donors promotes nucleasemediated targeted integration. Biotechnol. Bioeng. 110, 871-880 (2013).
-
(2013)
Biotechnol. Bioeng
, vol.110
, pp. 871-880
-
-
Cristea, S.1
-
9
-
-
84891722219
-
Highly efficient CRISPR/Cas9-mediated knock-in in zebrafish by homologyindependent DNA repair
-
Auer, T. O., Duroure, K., De Cian, A., Concordet, J. P. & Del Bene, F. Highly efficient CRISPR/Cas9-mediated knock-in in zebrafish by homologyindependent DNA repair. Genome Res. 24, 142-153 (2014).
-
(2014)
Genome Res
, vol.24
, pp. 142-153
-
-
Auer, T.O.1
Duroure, K.2
De Cian, A.3
Concordet, J.P.4
Del Bene, F.5
-
10
-
-
84874613680
-
Obligate ligation-gated recombination (ObLiGaRe): Custom-designed nuclease-mediated targeted integration through nonhomologous end joining
-
Maresca,M., Lin, V. G., Guo, N. & Yang, Y. Obligate ligation-gated recombination (ObLiGaRe): custom-designed nuclease-mediated targeted integration through nonhomologous end joining. Genome Res. 23, 539-546 (2013).
-
(2013)
Genome Res
, vol.23
, pp. 539-546
-
-
Lin, V.G.1
Guo, N.2
Yang, Y.3
-
11
-
-
84903516238
-
Microhomology-based choice of Cas9 nuclease target sites
-
Bae, S., Kweon, J., Kim, H. S. & Kim, J. S. Microhomology-based choice of Cas9 nuclease target sites. Nat. Methods 11, 705-706 (2014).
-
(2014)
Nat. Methods
, vol.11
, pp. 705-706
-
-
Bae, S.1
Kweon, J.2
Kim, H.S.3
Kim, J.S.4
-
12
-
-
54849404458
-
MMEJ repair of double-strand breaks (director's cut): Deleted sequences and alternative endings
-
McVey, M. & Lee, S. E. MMEJ repair of double-strand breaks (director's cut): deleted sequences and alternative endings. Trends Genet. 24, 529-538 (2008).
-
(2008)
Trends Genet
, vol.24
, pp. 529-538
-
-
McVey, M.1
Lee, S.E.2
-
13
-
-
84884203599
-
Biochemical DSB-repair model for mammalian cells in G1 and early S phases of the cell cycle
-
Taleei, R. & Nikjoo, H. Biochemical DSB-repair model for mammalian cells in G1 and early S phases of the cell cycle. Mutat. Res. 756, 206-212 (2013).
-
(2013)
Mutat. Res
, vol.756
, pp. 206-212
-
-
Taleei, R.1
Nikjoo, H.2
-
14
-
-
79551685675
-
A TALE nuclease architecture for efficient genome editing
-
Miller, J. C. et al. A TALE nuclease architecture for efficient genome editing. Nat. Biotechnol. 29, 143-148 (2011).
-
(2011)
Nat. Biotechnol
, vol.29
, pp. 143-148
-
-
Miller, J.C.1
-
15
-
-
84889597147
-
Repeating pattern of non-RVD variations in DNA-binding modules enhances TALEN activity
-
Sakuma, T. et al. Repeating pattern of non-RVD variations in DNA-binding modules enhances TALEN activity. Sci. Rep. 3, 3379 (2013).
-
(2013)
Sci. Rep
, vol.3
, pp. 3379
-
-
Sakuma, T.1
-
16
-
-
84877578867
-
A bright monomeric green fluorescent protein derived from Branchiostoma lanceolatum
-
Shaner, N. C. et al. A bright monomeric green fluorescent protein derived from Branchiostoma lanceolatum. Nat. Methods 10, 407-409 (2013).
-
(2013)
Nat. Methods
, vol.10
, pp. 407-409
-
-
Shaner, N.C.1
-
17
-
-
84892670583
-
Recent progress in genome engineering techniques in the silkworm
-
Daimon, T., Kiuchi, T. & Takasu, Y. Recent progress in genome engineering techniques in the silkworm, Bombyx mori. Dev. Growth Differ. 56, 14-25 (2014).
-
(2014)
Bombyx Mori. Dev. Growth Differ
, vol.56
, pp. 14-25
-
-
Daimon, T.1
Kiuchi, T.2
Takasu, Y.3
-
18
-
-
84884218077
-
Efficient TALEN construction for Bombyx mori gene targeting
-
Takasu, Y. et al. Efficient TALEN construction for Bombyx mori gene targeting. PLoS ONE 8, e73458 (2013).
-
(2013)
PLoS ONE
, vol.8
, pp. 73458
-
-
Takasu, Y.1
-
19
-
-
84904541006
-
Identification of a novel strong and ubiquitous promoter/enhancer in the silkworm
-
Tsubota, T. et al. Identification of a novel strong and ubiquitous promoter/enhancer in the silkworm, Bombyx mori. G3 4, 1347-1357 (2014).
-
(2014)
Bombyx Mori
, vol.G3
, Issue.4
, pp. 1347-1357
-
-
Tsubota, T.1
-
20
-
-
84974633017
-
High efficiency TALENs enable F0 functional analysis by targeted gene disruption in Xenopus laevis embryos
-
Suzuki, K. T. et al. High efficiency TALENs enable F0 functional analysis by targeted gene disruption in Xenopus laevis embryos. Biol. Open 2, 448-452 (2013).
-
(2013)
Biol. Open
, vol.2
, pp. 448-452
-
-
Suzuki, K.T.1
-
21
-
-
84892677890
-
Targeted mutagenesis of multiple and paralogous genes in Xenopus laevis using two pairs of transcription activator-like effector nucleases
-
Sakane, Y. et al. Targeted mutagenesis of multiple and paralogous genes in Xenopus laevis using two pairs of transcription activator-like effector nucleases. Dev. Growth Differ. 56, 108-114 (2014).
-
(2014)
Dev. Growth Differ
, vol.56
, pp. 108-114
-
-
Sakane, Y.1
-
22
-
-
79958248815
-
Spatiotemporal expression profile of no29/nucleophosmin3 in the intestine of Xenopus laevis during metamorphosis
-
Motoi, N., Hasebe, T., Suzuki, K. T. & Ishizuya-Oka, A. Spatiotemporal expression profile of no29/nucleophosmin3 in the intestine of Xenopus laevis during metamorphosis. Cell Tissue Res. 344, 445-453 (2011).
-
(2011)
Cell Tissue Res
, vol.344
, pp. 445-453
-
-
Motoi, N.1
Hasebe, T.2
Suzuki, K.T.3
Ishizuya-Oka, A.4
-
23
-
-
78649717516
-
Characterization of a novel type i keratin gene and generation of transgenic lines with fluorescent reporter genes driven by its promoter/enhancer in Xenopus laevis
-
Suzuki, K. T. et al. Characterization of a novel type I keratin gene and generation of transgenic lines with fluorescent reporter genes driven by its promoter/enhancer in Xenopus laevis. Dev. Dyn 239, 3172-3181 (2010).
-
(2010)
Dev. Dyn
, vol.239
, pp. 3172-3181
-
-
Suzuki, K.T.1
-
24
-
-
84880570576
-
High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells
-
Fu, Y. et al. High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells. Nat. Biotechnol. 31, 822-826 (2013).
-
(2013)
Nat. Biotechnol
, vol.31
, pp. 822-826
-
-
Fu, Y.1
-
25
-
-
84884165315
-
DNA targeting specificity of RNA-guided Cas9 nucleases
-
Hsu, P. D. et al. DNA targeting specificity of RNA-guided Cas9 nucleases. Nat. Biotechnol. 31, 827-832 (2013).
-
(2013)
Nat. Biotechnol
, vol.31
, pp. 827-832
-
-
Hsu, P.D.1
-
26
-
-
84884950106
-
CRISPR/Cas9 systems targeting b-globin and CCR5 genes have substantial off-target activity
-
Cradick, T. J., Fine, E. J., Antico, C. J. & Bao, G. CRISPR/Cas9 systems targeting b-globin and CCR5 genes have substantial off-target activity. Nucleic Acids Res. 41, 9584-9592 (2013).
-
(2013)
Nucleic Acids Res
, vol.41
, pp. 9584-9592
-
-
Cradick, T.J.1
Fine, E.J.2
Antico, C.J.3
Bao, G.4
-
27
-
-
78650028269
-
A robust system for production of minicircle DNA vectors
-
Kay, M. A., He, C. Y. & Chen, Z. Y. A robust system for production of minicircle DNA vectors. Nat. Biotechnol. 28, 1287-1289 (2010).
-
(2010)
Nat. Biotechnol
, vol.28
, pp. 1287-1289
-
-
Kay, M.A.1
He, C.Y.2
Chen, Z.Y.3
-
28
-
-
34447319080
-
An improved zinc-finger nuclease architecture for highly specific genome editing
-
Miller, J. C. et al. An improved zinc-finger nuclease architecture for highly specific genome editing. Nat. Biotechnol. 25, 778-785 (2007).
-
(2007)
Nat. Biotechnol
, vol.25
, pp. 778-785
-
-
Miller, J.C.1
-
29
-
-
34447323568
-
Structure-based redesign of the dimerization interface reduces the toxicity of zinc-finger nucleases
-
Szczepek, M. et al. Structure-based redesign of the dimerization interface reduces the toxicity of zinc-finger nucleases. Nat. Biotechnol. 25, 786-793 (2007).
-
(2007)
Nat. Biotechnol
, vol.25
, pp. 786-793
-
-
Szczepek, M.1
-
30
-
-
78650912707
-
Enhancing zinc-finger-nuclease activity with improved obligate heterodimeric architectures
-
Doyon, Y. et al. Enhancing zinc-finger-nuclease activity with improved obligate heterodimeric architectures. Nat. Methods 8, 74-79 (2011).
-
(2011)
Nat. Methods
, vol.8
, pp. 74-79
-
-
Doyon, Y.1
-
31
-
-
79960064013
-
Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting
-
Cermak, T. et al. Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting. Nucleic Acids Res. 39, e82 (2011).
-
(2011)
Nucleic Acids Res
, vol.39
, pp. 82
-
-
Cermak, T.1
-
32
-
-
84903217296
-
Multiplex genome engineering in human cells using all-in-one CRISPR/Cas9 vector system
-
Sakuma, T., Nishikawa, A., Kume, S., Chayama, K. & Yamamoto, T. Multiplex genome engineering in human cells using all-in-one CRISPR/Cas9 vector system. Sci. Rep. 4, 5400 (2014).
-
(2014)
Sci. Rep
, vol.4
, pp. 5400
-
-
Sakuma, T.1
Nishikawa, A.2
Kume, S.3
Chayama, K.4
Yamamoto, T.5
-
33
-
-
84898998318
-
An online bioinformatics tool predicts zinc finger and TALE nuclease off-target cleavage
-
Fine, E. J., Cradick, T. J., Zhao, C. L., Lin, Y. & Bao, G. An online bioinformatics tool predicts zinc finger and TALE nuclease off-target cleavage. Nucleic Acids Res. 42, e42 (2014).
-
(2014)
Nucleic Acids Res
, vol.42
, pp. 42
-
-
Fine, E.J.1
Cradick, T.J.2
Zhao, C.L.3
Lin, Y.4
Bao, G.5
-
34
-
-
84893396021
-
TALEN-mediated single-base-pair editing identification of an intergenic mutation upstream of BUB1B as causative of PCS (MVA) syndrome
-
Ochiai, H. et al. TALEN-mediated single-base-pair editing identification of an intergenic mutation upstream of BUB1B as causative of PCS (MVA) syndrome. Proc. Natl Acad. Sci. USA 111, 1461-1466 (2014).
-
(2014)
Proc. Natl Acad. Sci. USA
, vol.111
, pp. 1461-1466
-
-
Ochiai, H.1
|