Evolution of I-SceI Homing endonucleases with increased DNA recognition site specificity

Journal of Molecular Biology

Volumn 405, Issue 1, 2011, Pages 185-200

  Joshi, Rakesh ^a   Ho, Kwok Ki ^a   Tenney, Kristen ^a   Chen, Jui Hui ^b   Golden, Barbara L ^a   Gimble, Frederick S ^a  

^a PURDUE UNIVERSITY   (United States)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

directed evolution; homing enzyme; protein engineering; protein DNA interactions; specificity

Indexed keywords

ENDONUCLEASE; I SCEI HOMING ENDONUCLEASE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CRYSTAL STRUCTURE; DNA BINDING; DNA CLEAVAGE; ESCHERICHIA COLI; PRIORITY JOURNAL; PROTEIN DNA INTERACTION; PROTEIN ENGINEERING; PROTEIN EXPRESSION; PROTEIN PURIFICATION;

BACTERIA (MICROORGANISMS);

EID: 78650416018     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2010.10.029     Document Type: Article

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