Expanding the zinc-finger recombinase repertoire: Directed evolution and mutational analysis of serine recombinase specificity determinants

Nucleic Acids Research

Volumn 42, Issue 7, 2014, Pages 4755-4766

  Sirk, Shannon J ^a   Gaj, Thomas ^a   Jonsson, Andreas ^a,b   Mercer, Andrew C ^a,c   Barbas, Carlos F ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b ROYAL INSTITUTE OF TECHNOLOGY   (Sweden)

^c MEDIMMUNE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA RECOMBINASE; RECOMBINASE; SERINE RECOMBINASE; SIN RECOMBINASE; UNCLASSIFIED DRUG; ZINC FINGER RECOMBINASE;

ARTICLE; CATALYSIS; DNA BINDING; ENZYME SPECIFICITY; ESCHERICHIA COLI; GENETIC RECOMBINATION; GENETIC SCREENING; MOLECULAR EVOLUTION; MUTANT; MUTATIONAL ANALYSIS; NONHUMAN; PLASMID; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS PYOGENES;

CATALYTIC DOMAIN; DIRECTED MOLECULAR EVOLUTION; DNA-BINDING PROTEINS; GENOME, HUMAN; HUMANS; MUTAGENESIS; RECOMBINASES; RECOMBINATION, GENETIC; SUBSTRATE SPECIFICITY; ZINC FINGERS;

EID: 84899027573     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkt1389     Document Type: Article

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