Enhancing homology-directed genome editing by catalytically active and inactive CRISPR-Cas9 using asymmetric donor DNA

Nature Biotechnology

Volumn 34, Issue 3, 2016, Pages 339-344

  Richardson, Christopher D ^a   Ray, Graham J ^a   DeWitt, Mark A ^a   Curie, Gemma L ^a   Corn, Jacob E ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DISSOCIATION; EFFICIENCY; GENES; MOLECULAR BIOLOGY;

DNA STRANDS; DOUBLE-STRANDED DNA (DS-DNA); ERROR PRONES; HUMAN CELLS; NONHOMOLOGOUS END JOINING; SINGLE-STRANDED DNA;

DNA;

COMPLEMENTARY DNA; DNA; DOUBLE STRANDED DNA; SINGLE STRANDED DNA;

3' UNTRANSLATED REGION; ARTICLE; CATALYSIS; CONTROLLED STUDY; CRISPR CAS SYSTEM; DISSOCIATION; DNA BINDING; DNA CLEAVAGE; DNA END JOINING REPAIR; DNA REPAIR; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DNA INTERACTION; RNA EDITING; CELL LINE; DOUBLE STRANDED DNA BREAK; GENETIC ENGINEERING; GENETICS; GENOME; RECOMBINATION REPAIR;

CELL LINE; CRISPR-CAS SYSTEMS; DNA BREAKS, DOUBLE-STRANDED; DNA END-JOINING REPAIR; DNA, SINGLE-STRANDED; GENETIC ENGINEERING; GENOME; HUMANS; RECOMBINATIONAL DNA REPAIR; RNA EDITING;

EID: 84960911917     PISSN: 10870156     EISSN: 15461696     Source Type: Journal    
DOI: 10.1038/nbt.3481     Document Type: Article

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