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Volumn 44, Issue 6, 2015, Pages

Assays for DNA double-strand break repair by microhomology-based end-joining repair mechanisms

Author keywords

[No Author keywords available]

Indexed keywords

DNA POLYMERASE; DNA POLYMERASE THETA; GREEN FLUORESCENT PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; DNA; DNA DIRECTED DNA POLYMERASE;

EID: 84963795110     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkv1349     Document Type: Article
Times cited : (28)

References (48)
  • 1
    • 0036261707 scopus 로고    scopus 로고
    • Sensing and repairing DNA double-strand breaks
    • Jackson, S.P. (2002) Sensing and repairing DNA double-strand breaks. Carcinogenesis, 23, 687-696.
    • (2002) Carcinogenesis , vol.23 , pp. 687-696
    • Jackson, S.P.1
  • 2
    • 84865364870 scopus 로고    scopus 로고
    • Playing the end game: DNA double-strand break repair pathway choice
    • Chapman, J.R., Taylor, M.R.G. and Boulton, S.J. (2012) Playing the end game: DNA double-strand break repair pathway choice. Mol. Cell, 47, 497-510.
    • (2012) Mol. Cell , vol.47 , pp. 497-510
    • Chapman, J.R.1    Taylor, M.R.G.2    Boulton, S.J.3
  • 3
    • 78649449207 scopus 로고    scopus 로고
    • Coping with DNA double strand breaks
    • Hiom, K. (2010) Coping with DNA double strand breaks. DNA Repair (Amst)., 9, 1256-1263.
    • (2010) DNA Repair (Amst). , vol.9 , pp. 1256-1263
    • Hiom, K.1
  • 4
    • 52049098230 scopus 로고    scopus 로고
    • Comparison of nonhomologous end joining and homologous recombination in human cells
    • Mao, Z., Bozzella, M., Seluanov, A. and Gorbunova, V. (2008) Comparison of nonhomologous end joining and homologous recombination in human cells. DNA Repair (Amst)., 7, 1765-1771.
    • (2008) DNA Repair (Amst). , vol.7 , pp. 1765-1771
    • Mao, Z.1    Bozzella, M.2    Seluanov, A.3    Gorbunova, V.4
  • 5
    • 46249131123 scopus 로고    scopus 로고
    • Alternative-NHEJ is a mechanistically distinct pathway of mammalian chromosome break repair
    • Bennardo, N., Cheng, A., Huang, N. and Stark, J.M. (2008) Alternative-NHEJ is a mechanistically distinct pathway of mammalian chromosome break repair. PLoS Genet., 4, e1000110.
    • (2008) PLoS Genet. , vol.4 , pp. e1000110
    • Bennardo, N.1    Cheng, A.2    Huang, N.3    Stark, J.M.4
  • 6
    • 0344012187 scopus 로고    scopus 로고
    • Biochemical evidence for Ku-independent backup pathways of NHEJ
    • Wang, H., Perrault, A.R., Takeda, Y., Qin, W. and Iliakis, G. (2003) Biochemical evidence for Ku-independent backup pathways of NHEJ. Nucleic Acids Res., 31, 5377-5388.
    • (2003) Nucleic Acids Res. , vol.31 , pp. 5377-5388
    • Wang, H.1    Perrault, A.R.2    Takeda, Y.3    Qin, W.4    Iliakis, G.5
  • 7
    • 11244280890 scopus 로고    scopus 로고
    • Involvement of poly(ADP-ribose) polymerase-1 and XRCC1/DNA ligase III in an alternative route for DNA double-strand breaks rejoining
    • Audebert, M., Salles, B. and Calsou, P. (2004) Involvement of poly(ADP-ribose) polymerase-1 and XRCC1/DNA ligase III in an alternative route for DNA double-strand breaks rejoining. J. Biol. Chem., 279, 55117-55126.
    • (2004) J. Biol. Chem. , vol.279 , pp. 55117-55126
    • Audebert, M.1    Salles, B.2    Calsou, P.3
  • 9
    • 80053212145 scopus 로고    scopus 로고
    • Human Mre11/human Rad50/Nbs1 and DNA ligase IIIalpha/XRCC1 protein complexes act together in an alternative nonhomologous end joining pathway
    • Della-Maria, J., Zhou, Y., Tsai, M.-S., Kuhnlein, J., Carney, J.P., Paull, T.T. and Tomkinson, A.E. (2011) Human Mre11/human Rad50/Nbs1 and DNA ligase IIIalpha/XRCC1 protein complexes act together in an alternative nonhomologous end joining pathway. J. Biol. Chem., 286, 33845-33853.
    • (2011) J. Biol. Chem. , vol.286 , pp. 33845-33853
    • Della-Maria, J.1    Zhou, Y.2    Tsai, M.-S.3    Kuhnlein, J.4    Carney, J.P.5    Paull, T.T.6    Tomkinson, A.E.7
  • 12
    • 1842294561 scopus 로고    scopus 로고
    • Ectopic mitotic recombination in Drosophila probed with bacterial beta-galactosidase gene-based reporter transgenes
    • Bärtsch, S., Dücker, K., Würgler, F.E. and Sengstag, C. (1997) Ectopic mitotic recombination in Drosophila probed with bacterial beta-galactosidase gene-based reporter transgenes. Nucleic Acids Res., 25, 3917-3924.
    • (1997) Nucleic Acids Res. , vol.25 , pp. 3917-3924
    • Bärtsch, S.1    Dücker, K.2    Würgler, F.E.3    Sengstag, C.4
  • 13
    • 0023117774 scopus 로고
    • Gene recombination in X-ray-sensitive hamster cells
    • Hamilton, A.A. and Thacker, J. (1987) Gene recombination in X-ray-sensitive hamster cells. Mol. Cell. Biol., 7, 1409-1414.
    • (1987) Mol. Cell. Biol. , vol.7 , pp. 1409-1414
    • Hamilton, A.A.1    Thacker, J.2
  • 14
    • 0021234022 scopus 로고
    • Homologous recombination between plasmids in mammalian cells can be enhanced by treatment of input DNA
    • Kucherlapati, R.S., Eves, E.M., Song, K.Y., Morse, B.S. and Smithies, O. (1984) Homologous recombination between plasmids in mammalian cells can be enhanced by treatment of input DNA. Proc. Natl. Acad. Sci. U.S.A., 81, 3153-3157.
    • (1984) Proc. Natl. Acad. Sci. U.S.A. , vol.81 , pp. 3153-3157
    • Kucherlapati, R.S.1    Eves, E.M.2    Song, K.Y.3    Morse, B.S.4    Smithies, O.5
  • 15
    • 0026643754 scopus 로고
    • Extrachromosomal homologous DNA recombination in plant cells is fast and is not affected by CpG methylation
    • Puchta, H., Kocher, S. and Hohn, B. (1992) Extrachromosomal homologous DNA recombination in plant cells is fast and is not affected by CpG methylation. Mol. Cell. Biol., 12, 3372-3379.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 3372-3379
    • Puchta, H.1    Kocher, S.2    Hohn, B.3
  • 16
    • 0021742268 scopus 로고
    • The minimum amount of homology required for homologous recombination in mammalian cells
    • Rubnitz, J. and Subramani, S. (1984) The minimum amount of homology required for homologous recombination in mammalian cells. Mol. Cell. Biol., 4, 2253-2258.
    • (1984) Mol. Cell. Biol. , vol.4 , pp. 2253-2258
    • Rubnitz, J.1    Subramani, S.2
  • 17
    • 0023428022 scopus 로고
    • Intermolecular homologous recombination between transfected sequences in mammalian cells is primarily nonconservative
    • Seidman, M.M. (1987) Intermolecular homologous recombination between transfected sequences in mammalian cells is primarily nonconservative. Mol. Cell. Biol., 7, 3561-3565.
    • (1987) Mol. Cell. Biol. , vol.7 , pp. 3561-3565
    • Seidman, M.M.1
  • 19
    • 27544434114 scopus 로고    scopus 로고
    • The Mre11/Rad50/Xrs2 complex and non-homologous end-joining of incompatible ends in S. Cerevisiae
    • Zhang, X. and Paull, T.T. (2005) The Mre11/Rad50/Xrs2 complex and non-homologous end-joining of incompatible ends in S. cerevisiae. DNA Repair (Amst)., 4, 1281-1294.
    • (2005) DNA Repair (Amst). , vol.4 , pp. 1281-1294
    • Zhang, X.1    Paull, T.T.2
  • 20
    • 84905370561 scopus 로고    scopus 로고
    • DNA ligase III and DNA ligase IV carry out genetically distinct forms of end joining in human somatic cells
    • Oh, S., Harvey, A., Zimbric, J., Wang, Y., Nguyen, T., Jackson, P.J. and Hendrickson, E.A. (2014) DNA ligase III and DNA ligase IV carry out genetically distinct forms of end joining in human somatic cells. DNA Repair (Amst)., 21, 97-110.
    • (2014) DNA Repair (Amst). , vol.21 , pp. 97-110
    • Oh, S.1    Harvey, A.2    Zimbric, J.3    Wang, Y.4    Nguyen, T.5    Jackson, P.J.6    Hendrickson, E.A.7
  • 21
    • 84877321963 scopus 로고    scopus 로고
    • Microhomology-mediated end joining and homologous recombination share the initial end resection step to repair DNA double-strand breaks in mammalian cells
    • Truong, L.N., Li, Y., Shi, L.Z., Hwang, P.Y.-H., He, J., Wang, H. and Razavian, N. (2013) Microhomology-mediated End Joining and Homologous Recombination share the initial end resection step to repair DNA double-strand breaks in mammalian cells. PNAS, 110, 7720-7725.
    • (2013) PNAS , vol.110 , pp. 7720-7725
    • Truong, L.N.1    Li, Y.2    Shi, L.Z.3    Hwang, P.Y.-H.4    He, J.5    Wang, H.6    Razavian, N.7
  • 22
    • 84862282124 scopus 로고    scopus 로고
    • CtIP protein dimerization is critical for its recruitment to chromosomal DNA double-stranded breaks
    • Wang, H., Shao, Z., Shi, L.Z., Hwang, P.Y.-H., Truong, L.N., Berns, M.W., Chen, D.J. and Wu, X. (2012) CtIP protein dimerization is critical for its recruitment to chromosomal DNA double-stranded breaks. J. Biol. Chem., 287, 21471-21480.
    • (2012) J. Biol. Chem. , vol.287 , pp. 21471-21480
    • Wang, H.1    Shao, Z.2    Shi, L.Z.3    Hwang, P.Y.-H.4    Truong, L.N.5    Berns, M.W.6    Chen, D.J.7    Wu, X.8
  • 23
    • 77957235402 scopus 로고    scopus 로고
    • Synthesis-dependent microhomology-mediated end joining accounts for multiple types of repair junctions
    • Yu, A.M. and McVey, M. (2010) Synthesis-dependent microhomology-mediated end joining accounts for multiple types of repair junctions. Nucleic Acids Res., 38, 5706-5717.
    • (2010) Nucleic Acids Res. , vol.38 , pp. 5706-5717
    • Yu, A.M.1    McVey, M.2
  • 24
    • 84873634732 scopus 로고    scopus 로고
    • Competing roles of DNA end resection and non-homologous end joining functions in the repair of replication-born double-strand breaks by sister-chromatid recombination
    • Muñoz-Galván, S., López-Saavedra, A., Jackson, S.P., Huertas, P., Cortés-Ledesma, F. and Aguilera, A. (2013) Competing roles of DNA end resection and non-homologous end joining functions in the repair of replication-born double-strand breaks by sister-chromatid recombination. Nucleic Acids Res., 41, 1669-1683.
    • (2013) Nucleic Acids Res. , vol.41 , pp. 1669-1683
    • Muñoz-Galván, S.1    López-Saavedra, A.2    Jackson, S.P.3    Huertas, P.4    Cortés-Ledesma, F.5    Aguilera, A.6
  • 25
    • 84896703742 scopus 로고    scopus 로고
    • Quantitation of DNA double-strand break resection intermediates in human cells
    • Zhou, Y., Caron, P., Legube, G. and Paull, T.T. (2014) Quantitation of DNA double-strand break resection intermediates in human cells. Nucleic Acids Res., 42, e19.
    • (2014) Nucleic Acids Res. , vol.42 , pp. e19
    • Zhou, Y.1    Caron, P.2    Legube, G.3    Paull, T.T.4
  • 26
    • 0001127374 scopus 로고
    • Isolation of Chinese hamster cell mutants deficient in dihydrofolate reductase activity
    • Urlaub, G. and Chasin, L.A. (1980) Isolation of Chinese hamster cell mutants deficient in dihydrofolate reductase activity. Proc. Natl. Acad. Sci. U.S.A., 77, 4216-4220.
    • (1980) Proc. Natl. Acad. Sci. U.S.A. , vol.77 , pp. 4216-4220
    • Urlaub, G.1    Chasin, L.A.2
  • 28
    • 77957369329 scopus 로고    scopus 로고
    • Dual roles for DNA polymerase theta in alternative end-joining repair of double-strand breaks in Drosophila
    • Chan, S.H., Yu, A.M. and McVey, M. (2010) Dual roles for DNA polymerase theta in alternative end-joining repair of double-strand breaks in Drosophila. PLoS Genet., 6, 1-16.
    • (2010) PLoS Genet. , vol.6 , pp. 1-16
    • Chan, S.H.1    Yu, A.M.2    McVey, M.3
  • 30
    • 34548401682 scopus 로고    scopus 로고
    • Saccharomyces cerevisiae Sae2- and Tel1-dependent single-strand DNA formation at DNA break promotes microhomology-mediated end joining
    • Lee, K. and Lee, S.E. (2007) Saccharomyces cerevisiae Sae2- and Tel1-dependent single-strand DNA formation at DNA break promotes microhomology-mediated end joining. Genetics, 176, 2003-2014.
    • (2007) Genetics , vol.176 , pp. 2003-2014
    • Lee, K.1    Lee, S.E.2
  • 31
    • 45549094090 scopus 로고    scopus 로고
    • Human DNA ligases i and III, but not ligase IV, are required for microhomology-mediated end joining of DNA double-strand breaks
    • Liang, L., Deng, L., Nguyen, S.C., Zhao, X., Maulion, C.D., Shao, C. and Tischfield, J.A. (2008) Human DNA ligases I and III, but not ligase IV, are required for microhomology-mediated end joining of DNA double-strand breaks. Nucleic Acids Res., 36, 3297-310.
    • (2008) Nucleic Acids Res. , vol.36 , pp. 3297-3310
    • Liang, L.1    Deng, L.2    Nguyen, S.C.3    Zhao, X.4    Maulion, C.D.5    Shao, C.6    Tischfield, J.A.7
  • 33
    • 34547132093 scopus 로고    scopus 로고
    • Microhomology-mediated end joining in fission yeast is repressed by pku70 and relies on genes involved in homologous recombination
    • Decottignies, A. (2007) Microhomology-mediated end joining in fission yeast is repressed by pku70 and relies on genes involved in homologous recombination. Genetics, 176, 1403-1415.
    • (2007) Genetics , vol.176 , pp. 1403-1415
    • Decottignies, A.1
  • 36
    • 77951279075 scopus 로고    scopus 로고
    • Reactive oxygen species in cancer
    • Liou, G.-Y. and Peter, S. (2010) Reactive oxygen species in cancer. Free Radic. Res., 44, 479-496.
    • (2010) Free Radic. Res. , vol.44 , pp. 479-496
    • Liou, G.-Y.1    Peter, S.2
  • 37
    • 0026021362 scopus 로고
    • Production of large amounts of hydrogen peroxide by human tumor cells
    • Szatrowski, T.P. and Nathan, C.F. (1991) Production of large amounts of hydrogen peroxide by human tumor cells. Cancer Res., 51, 794-798.
    • (1991) Cancer Res. , vol.51 , pp. 794-798
    • Szatrowski, T.P.1    Nathan, C.F.2
  • 38
    • 5144225797 scopus 로고    scopus 로고
    • DNA double strand break repair in human bladder cancer is error prone and involves microhomology-associated end-joining
    • Bentley, J., Diggle, C.P., Harnden, P., Knowles, M.A. and Kiltie, A.E. (2004) DNA double strand break repair in human bladder cancer is error prone and involves microhomology-associated end-joining. Nucleic Acids Res., 32, 5249-5259.
    • (2004) Nucleic Acids Res. , vol.32 , pp. 5249-5259
    • Bentley, J.1    Diggle, C.P.2    Harnden, P.3    Knowles, M.A.4    Kiltie, A.E.5
  • 40
    • 0029618936 scopus 로고
    • Determination of DNA persistence length by cryo-electron microscopy. Separation of the static and dynamic contributions to the apparent persistence length of DNA
    • Bednar, J., Furrer, P., Katritch, V., Stasiak, a.Z., Dubochet, J. and Stasiak, A. (1995) Determination of DNA persistence length by cryo-electron microscopy. Separation of the static and dynamic contributions to the apparent persistence length of DNA. J. Mol. Biol., 254, 579-594.
    • (1995) J. Mol. Biol. , vol.254 , pp. 579-594
    • Bednar, J.1    Furrer, P.2    Katritch, V.3    Stasiak, A.Z.4    Dubochet, J.5    Stasiak, A.6
  • 42
    • 0000579305 scopus 로고    scopus 로고
    • DNA persistence length revisited
    • Lu, Y., Weers, B. and Stellwagen, N.C. (2002) DNA persistence length revisited. Biopolymers, 61, 261-275.
    • (2002) Biopolymers , vol.61 , pp. 261-275
    • Lu, Y.1    Weers, B.2    Stellwagen, N.C.3
  • 45
    • 84893870945 scopus 로고    scopus 로고
    • A Polymerase Theta-dependent repair pathway suppresses extensive genomic instability at endogenous G4 DNA sites
    • Koole, W., van Schendel, R., Karambelas, A.E., van Heteren, J.T., Okihara, K.L. and Tijsterman, M. (2014) A Polymerase Theta-dependent repair pathway suppresses extensive genomic instability at endogenous G4 DNA sites. Nat. Commun., 5, 3216.
    • (2014) Nat. Commun. , vol.5 , pp. 3216
    • Koole, W.1    Van Schendel, R.2    Karambelas, A.E.3    Van Heteren, J.T.4    Okihara, K.L.5    Tijsterman, M.6
  • 47
    • 43349088569 scopus 로고    scopus 로고
    • Distinct roles of XRCC4 and Ku80 in non-homologous end-joining of endonuclease- and ionizing radiation-induced DNA double-strand breaks
    • Schulte-Uentrop, L., El-Awady, R.A., Schliecker, L., Willers, H. and Dahm-Daphi, J. (2008) Distinct roles of XRCC4 and Ku80 in non-homologous end-joining of endonuclease- and ionizing radiation-induced DNA double-strand breaks. Nucleic Acids Res., 36, 2561-2569.
    • (2008) Nucleic Acids Res. , vol.36 , pp. 2561-2569
    • Schulte-Uentrop, L.1    El-Awady, R.A.2    Schliecker, L.3    Willers, H.4    Dahm-Daphi, J.5
  • 48
    • 0035164722 scopus 로고    scopus 로고
    • Homologous recombination in extrachromosomal plasmid substrates is not suppressed by p53
    • Willers, H., McCarthy, E.E., Hubbe, P., Dahm-Daphi, J. and Powell, S.N. (2001) Homologous recombination in extrachromosomal plasmid substrates is not suppressed by p53. Carcinogenesis, 22, 1757-1763.
    • (2001) Carcinogenesis , vol.22 , pp. 1757-1763
    • Willers, H.1    McCarthy, E.E.2    Hubbe, P.3    Dahm-Daphi, J.4    Powell, S.N.5


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