메뉴 건너뛰기




Volumn 111, Issue 9, 2014, Pages 1740-1747

Engineering of chromosomal wax ester synthase integrated Saccharomyces cerevisiae mutants for improved biosynthesis of fatty acid ethyl esters

Author keywords

ACBP; Delta sequence; FAEEs; gapN; Homologous recombination; Metabolic engineering

Indexed keywords

BIOCHEMISTRY; DNA; ESTERIFICATION; ESTERS; FATTY ACIDS; GENES; INTEGRATION; METABOLIC ENGINEERING;

EID: 84904862031     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.25234     Document Type: Article
Times cited : (72)

References (52)
  • 1
    • 70449686525 scopus 로고    scopus 로고
    • Characterization of chromosomal integration sites for heterologous gene expression in Saccharomyces cerevisiae
    • Bai Flagfeldt D, Siewers V, Huang L, Nielsen J. 2009. Characterization of chromosomal integration sites for heterologous gene expression in Saccharomyces cerevisiae. Yeast 26(10):545-551.
    • (2009) Yeast , vol.26 , Issue.10 , pp. 545-551
    • Bai Flagfeldt, D.1    Siewers, V.2    Huang, L.3    Nielsen, J.4
  • 2
    • 0034799097 scopus 로고    scopus 로고
    • Chromosomal editing in Escherichia coli
    • Balbás P, Gosset G. 2001. Chromosomal editing in Escherichia coli. Mol Biotechnol 19(1):1-12.
    • (2001) Mol Biotechnol , vol.19 , Issue.1 , pp. 1-12
    • Balbás, P.1    Gosset, G.2
  • 3
    • 0023990722 scopus 로고
    • The Saccharomyces cerevisiae genome contains functional and nonfunctional copies of transposon Ty1
    • Boeke JD, Eichinger D, Castrillon D, Fink GR. 1988. The Saccharomyces cerevisiae genome contains functional and nonfunctional copies of transposon Ty1. Mol Cell Biol 8(4):1432-1442.
    • (1988) Mol Cell Biol , vol.8 , Issue.4 , pp. 1432-1442
    • Boeke, J.D.1    Eichinger, D.2    Castrillon, D.3    Fink, G.R.4
  • 4
    • 33644832381 scopus 로고    scopus 로고
    • In silico aided metabolic engineering of Saccharomyces cerevisiae for improved bioethanol production
    • Bro C, Regenberg B, Forster J, Nielsen J. 2006. In silico aided metabolic engineering of Saccharomyces cerevisiae for improved bioethanol production. Metab Eng 8(2):102-111.
    • (2006) Metab Eng , vol.8 , Issue.2 , pp. 102-111
    • Bro, C.1    Regenberg, B.2    Forster, J.3    Nielsen, J.4
  • 5
    • 79955158679 scopus 로고    scopus 로고
    • Evolutionary engineered Saccharomyces cerevisiae wine yeast strains with increased in vivo flux through the pentose phosphate pathway
    • Cadière A, Ortiz-Julien A, Camarasa C, Dequin S. 2011. Evolutionary engineered Saccharomyces cerevisiae wine yeast strains with increased in vivo flux through the pentose phosphate pathway. Metab Eng 13(3):263-271.
    • (2011) Metab Eng , vol.13 , Issue.3 , pp. 263-271
    • Cadière, A.1    Ortiz-Julien, A.2    Camarasa, C.3    Dequin, S.4
  • 6
    • 84863610089 scopus 로고    scopus 로고
    • Enhancing the copy number of episomal plasmids in Saccharomyces cerevisiae for improved protein production
    • Chen Y, Partow S, Scalcinati G, Siewers V, Nielsen J. 2012. Enhancing the copy number of episomal plasmids in Saccharomyces cerevisiae for improved protein production. FEMS Yeast Res 12:598-607.
    • (2012) FEMS Yeast Res , vol.12 , pp. 598-607
    • Chen, Y.1    Partow, S.2    Scalcinati, G.3    Siewers, V.4    Nielsen, J.5
  • 7
    • 0032999856 scopus 로고    scopus 로고
    • δ-Integration of endo/exo-glucanase and β-glucosidase genes into the yeast chromosomes for direct conversion of cellulose to ethanol
    • Cho KM, Yoo YJ, Kang HS. 1999. δ-Integration of endo/exo-glucanase and β-glucosidase genes into the yeast chromosomes for direct conversion of cellulose to ethanol. Enzyme Microb Technol 25:23-30.
    • (1999) Enzyme Microb Technol , vol.25 , pp. 23-30
    • Cho, K.M.1    Yoo, Y.J.2    Kang, H.S.3
  • 8
    • 0036270543 scopus 로고    scopus 로고
    • Transformation of yeast by lithium acetate/single-stranded carrier DNA/polyethylene glycol method
    • In: Christine G, Gerald RF, editors. San Diego, CA: Academic Press
    • Daniel Gietz R, Woods RA. 2002. Transformation of yeast by lithium acetate/single-stranded carrier DNA/polyethylene glycol method. In: Christine G, Gerald RF, editors. Methods Enzymol. San Diego, CA: Academic Press. p 87-96.
    • (2002) Methods Enzymol , pp. 87-96
    • Daniel Gietz, R.1    Woods, R.A.2
  • 9
    • 0025259125 scopus 로고
    • Application of a ribosomal DNA integration vector in the construction of a brewer's yeast having alpha-acetolactate decarboxylase activity
    • Fujii T, Kondo K, Shimizu F, Sone H, Tanaka J, Inoue T. 1990. Application of a ribosomal DNA integration vector in the construction of a brewer's yeast having alpha-acetolactate decarboxylase activity. Appl Environ Microbiol 56(4):997-1003.
    • (1990) Appl Environ Microbiol , vol.56 , Issue.4 , pp. 997-1003
    • Fujii, T.1    Kondo, K.2    Shimizu, F.3    Sone, H.4    Tanaka, J.5    Inoue, T.6
  • 10
    • 0442309687 scopus 로고    scopus 로고
    • Effects of gene dosage, promoters, and substrates on unfolded protein stress of recombinant Pichia pastoris
    • Hohenblum H, Gasser B, Maurer M, Borth N, Mattanovich D. 2004. Effects of gene dosage, promoters, and substrates on unfolded protein stress of recombinant Pichia pastoris. Biotechnol Bioeng 85(4):367-375.
    • (2004) Biotechnol Bioeng , vol.85 , Issue.4 , pp. 367-375
    • Hohenblum, H.1    Gasser, B.2    Maurer, M.3    Borth, N.4    Mattanovich, D.5
  • 12
    • 10444228204 scopus 로고    scopus 로고
    • Synthesis of novel lipids in Saccharomyces cerevisiae by heterologous expression of an unspecific bacterial acyltransferase
    • Kalscheuer R, Luftmann H, Steinbüchel A. 2004. Synthesis of novel lipids in Saccharomyces cerevisiae by heterologous expression of an unspecific bacterial acyltransferase. Appl Environ Microbiol 70:7119-7125.
    • (2004) Appl Environ Microbiol , vol.70 , pp. 7119-7125
    • Kalscheuer, R.1    Luftmann, H.2    Steinbüchel, A.3
  • 13
    • 33748762752 scopus 로고    scopus 로고
    • Microdiesel: Escherichia coli engineered for fuel production
    • Kalscheuer R, Stölting T, Steinbüchel A. 2006. Microdiesel: Escherichia coli engineered for fuel production. Microbiology 152(9):2529-2536.
    • (2006) Microbiology , vol.152 , Issue.9 , pp. 2529-2536
    • Kalscheuer, R.1    Stölting, T.2    Steinbüchel, A.3
  • 14
    • 84859772410 scopus 로고    scopus 로고
    • Synthetic biology and the development of tools for metabolic engineering
    • Keasling JD. 2012. Synthetic biology and the development of tools for metabolic engineering. Metab Eng 14(3):189-195.
    • (2012) Metab Eng , vol.14 , Issue.3 , pp. 189-195
    • Keasling, J.D.1
  • 15
    • 0035936615 scopus 로고    scopus 로고
    • Enhanced production of anticoagulant hirudin in recombinant Saccharomyces cerevisiae by chromosomal δ-integration
    • Kim MD, Rhee SK, Seo JH. 2001. Enhanced production of anticoagulant hirudin in recombinant Saccharomyces cerevisiae by chromosomal δ-integration. J Biotechnol 85(1):41-48.
    • (2001) J Biotechnol , vol.85 , Issue.1 , pp. 41-48
    • Kim, M.D.1    Rhee, S.K.2    Seo, J.H.3
  • 16
    • 0029561055 scopus 로고
    • Production of HM-1 killer toxin in Saccharomyces cerevisiae transformed with the PDR4 gene and δ-sequence-mediated multi-integration system
    • Kimura T, Kitamoto N, Iimura Y, Kito Y. 1995. Production of HM-1 killer toxin in Saccharomyces cerevisiae transformed with the PDR4 gene and δ-sequence-mediated multi-integration system. J Ferment Bioeng 80(5):423-428.
    • (1995) J Ferment Bioeng , vol.80 , Issue.5 , pp. 423-428
    • Kimura, T.1    Kitamoto, N.2    Iimura, Y.3    Kito, Y.4
  • 19
    • 0026666508 scopus 로고
    • A multisite integrative cassette for the yeast Saccharomyces cerevisiae
    • Kudia B, Nicolas A. 1992. A multisite integrative cassette for the yeast Saccharomyces cerevisiae. Gene 119(1):49-56.
    • (1992) Gene , vol.119 , Issue.1 , pp. 49-56
    • Kudia, B.1    Nicolas, A.2
  • 20
    • 0030813336 scopus 로고    scopus 로고
    • Stabilization of yeast artificial chromosome clones in a rad 54-3 recombination-deficient host strain
    • Le Y, Dobson MJ. 1997. Stabilization of yeast artificial chromosome clones in a rad 54-3 recombination-deficient host strain. Nucleic Acids Res 25(6):1248-1253.
    • (1997) Nucleic Acids Res , vol.25 , Issue.6 , pp. 1248-1253
    • Le, Y.1    Dobson, M.J.2
  • 21
    • 29544439347 scopus 로고    scopus 로고
    • Application of sequential integration for metabolic engineering of 1,2-propanediol production in yeast
    • Lee W, Da Silva N. 2006. Application of sequential integration for metabolic engineering of 1, 2-propanediol production in yeast. Metab Eng 8:58-65.
    • (2006) Metab Eng , vol.8 , pp. 58-65
    • Lee, W.1    Da Silva, N.2
  • 22
    • 0030882849 scopus 로고    scopus 로고
    • Improved efficiency and stability of multiple cloned gene insertions at the δ sequences of Saccharomyces cerevisiae
    • Lee FWF, Silva NAD. 1997. Improved efficiency and stability of multiple cloned gene insertions at the δ sequences of Saccharomyces cerevisiae. Appl Microbiol Biotechnol 48(3):339-345.
    • (1997) Appl Microbiol Biotechnol , vol.48 , Issue.3 , pp. 339-345
    • Lee, F.W.F.1    Silva, N.A.D.2
  • 23
    • 0025026094 scopus 로고
    • Stability of integrated plasmids in the chromosome of Lactococcus lactis
    • Leenhouts KJ, Kok J, Venema G. 1990. Stability of integrated plasmids in the chromosome of Lactococcus lactis. Appl Environ Microbiol 56(9):2726-2735.
    • (1990) Appl Environ Microbiol , vol.56 , Issue.9 , pp. 2726-2735
    • Leenhouts, K.J.1    Kok, J.2    Venema, G.3
  • 24
    • 18944382213 scopus 로고    scopus 로고
    • Happy together: The life and times of Ty retrotransposons and their hosts
    • Lesage P, Todeschini AL. 2005. Happy together: The life and times of Ty retrotransposons and their hosts. Cytogenet Genome Res 110:70-90.
    • (2005) Cytogenet Genome Res , vol.110 , pp. 70-90
    • Lesage, P.1    Todeschini, A.L.2
  • 25
    • 0035902544 scopus 로고    scopus 로고
    • Rad52 forms DNA repair and recombination centers during S phase
    • Lisby M, Rothstein R, Mortensen UH. 2001. Rad52 forms DNA repair and recombination centers during S phase. Proc Natl Acad Sci USA 98(15):8276-8282.
    • (2001) Proc Natl Acad Sci USA , vol.98 , Issue.15 , pp. 8276-8282
    • Lisby, M.1    Rothstein, R.2    Mortensen, U.H.3
  • 26
    • 84862807811 scopus 로고    scopus 로고
    • Different expression systems for production of recombinant proteins in Saccharomyces cerevisiae
    • Liu Z, Tyo K, Martínez J, Petranovic D, Nielsen J. 2012. Different expression systems for production of recombinant proteins in Saccharomyces cerevisiae. Biotechnol Bioeng 109(5):1259-1268.
    • (2012) Biotechnol Bioeng , vol.109 , Issue.5 , pp. 1259-1268
    • Liu, Z.1    Tyo, K.2    Martínez, J.3    Petranovic, D.4    Nielsen, J.5
  • 27
    • 83055180451 scopus 로고    scopus 로고
    • Engineering Escherichia coli for biodiesel production utilizing a bacterial fatty acid methyltransferase
    • Nawabi P, Bauer S, Kyrpides N, Lykidis A. 2011. Engineering Escherichia coli for biodiesel production utilizing a bacterial fatty acid methyltransferase. Appl Environ Microbiol 77(22):8052-8061.
    • (2011) Appl Environ Microbiol , vol.77 , Issue.22 , pp. 8052-8061
    • Nawabi, P.1    Bauer, S.2    Kyrpides, N.3    Lykidis, A.4
  • 28
    • 71149116560 scopus 로고    scopus 로고
    • Systems biology of lipid metabolism: From yeast to human
    • Nielsen J. 2009. Systems biology of lipid metabolism: From yeast to human. FEBS Lett 583(24):3905-3913.
    • (2009) FEBS Lett , vol.583 , Issue.24 , pp. 3905-3913
    • Nielsen, J.1
  • 29
    • 34248213118 scopus 로고    scopus 로고
    • Development of stable flocculent Saccharomyces cerevisiae strain for continuous Aspergillus niger β-galactosidase production
    • Oliveira C, Teixeira JA, Lima N, Da Silva NA, Domingues L. 2007. Development of stable flocculent Saccharomyces cerevisiae strain for continuous Aspergillus niger β-galactosidase production. J Biosci Bioeng 103(4):318-324.
    • (2007) J Biosci Bioeng , vol.103 , Issue.4 , pp. 318-324
    • Oliveira, C.1    Teixeira, J.A.2    Lima, N.3    Da Silva, N.A.4    Domingues, L.5
  • 30
    • 78149328427 scopus 로고    scopus 로고
    • Characterization of different promoters for designing a new expression vector in Saccharomyces cerevisiae
    • Partow S, Siewers V, Bjørn S, Nielsen J, Maury J. 2010. Characterization of different promoters for designing a new expression vector in Saccharomyces cerevisiae. Yeast 27:955-964.
    • (2010) Yeast , vol.27 , pp. 955-964
    • Partow, S.1    Siewers, V.2    Bjørn, S.3    Nielsen, J.4    Maury, J.5
  • 31
    • 33751510874 scopus 로고    scopus 로고
    • Sequential gene integration for the engineering of Kluyveromyces marxianus
    • Pecota DC, Rajgarhia V, Da Silva NA. 2007. Sequential gene integration for the engineering of Kluyveromyces marxianus. J Biotechnol 127(3):408-416.
    • (2007) J Biotechnol , vol.127 , Issue.3 , pp. 408-416
    • Pecota, D.C.1    Rajgarhia, V.2    Da Silva, N.A.3
  • 32
    • 0027295334 scopus 로고
    • Interaction of acyl-CoA binding protein (ACBP) on processes for which acyl-CoA is a substrate, product or inhibitor
    • Rasmussen J, Rosendal J, Knudsen J. 1993. Interaction of acyl-CoA binding protein (ACBP) on processes for which acyl-CoA is a substrate, product or inhibitor. Biochem J 292:907.
    • (1993) Biochem J , vol.292 , pp. 907
    • Rasmussen, J.1    Rosendal, J.2    Knudsen, J.3
  • 33
    • 34249301015 scopus 로고    scopus 로고
    • Engineering of the methylmalonyl-CoA metabolite node of Saccharopolyspora erythraea for increased erythromycin production
    • Reeves AR, Brikun IA, Cernota WH, Leach BI, Gonzalez MC, Mark Weber J. 2007. Engineering of the methylmalonyl-CoA metabolite node of Saccharopolyspora erythraea for increased erythromycin production. Metab Eng 9(3):293-303.
    • (2007) Metab Eng , vol.9 , Issue.3 , pp. 293-303
    • Reeves, A.R.1    Brikun, I.A.2    Cernota, W.H.3    Leach, B.I.4    Gonzalez, M.C.5    Mark Weber, J.6
  • 34
    • 84891829362 scopus 로고    scopus 로고
    • Metabolic engineering of Saccharomyces cerevisiae for production of fatty acid-derived biofuels and chemicals
    • Runguphan W, Keasling JD. 2013. Metabolic engineering of Saccharomyces cerevisiae for production of fatty acid-derived biofuels and chemicals. Metab Eng 21:103-113.
    • (2013) Metab Eng , vol.21 , pp. 103-113
    • Runguphan, W.1    Keasling, J.D.2
  • 36
    • 84904875672 scopus 로고    scopus 로고
    • Manipulation of acyl-CoA binding protein expression for altered lipid production in microbial hosts. US 2009/0291479A1.
    • Seung-Pyo H, Zhixiong X. 2009. Manipulation of acyl-CoA binding protein expression for altered lipid production in microbial hosts. US 2009/0291479A1.
    • (2009)
    • Seung-Pyo, H.1    Zhixiong, X.2
  • 37
    • 84882948295 scopus 로고    scopus 로고
    • Impact of gene dosage on the production of lipase from Rhizopus chinensis CCTCC M201021 in Pichia pastoris
    • Sha C, Yu X-W, Li F, Xu Y. 2013. Impact of gene dosage on the production of lipase from Rhizopus chinensis CCTCC M201021 in Pichia pastoris. Appl Biochem Biotechnol 169(4):1160-1172.
    • (2013) Appl Biochem Biotechnol , vol.169 , Issue.4 , pp. 1160-1172
    • Sha, C.1    Yu, X.-W.2    Li, F.3    Xu, Y.4
  • 38
    • 84857243863 scopus 로고    scopus 로고
    • Functional expression and characterization of five wax ester synthases in Saccharomyces cerevisiae and their utility for biodiesel production
    • Shi S, Valle-Rodríguez JO, Khoomrung S, Siewers V, Nielsen J. 2012. Functional expression and characterization of five wax ester synthases in Saccharomyces cerevisiae and their utility for biodiesel production. Biotechnol Biofuels 5(1):7.
    • (2012) Biotechnol Biofuels , vol.5 , Issue.1 , pp. 7
    • Shi, S.1    Valle-Rodríguez, J.O.2    Khoomrung, S.3    Siewers, V.4    Nielsen, J.5
  • 39
    • 84872131864 scopus 로고    scopus 로고
    • Activating transhydrogenase and NAD kinase in combination for improving isobutanol production
    • Shi A, Zhu X, Lu J, Zhang X, Ma Y. 2013. Activating transhydrogenase and NAD kinase in combination for improving isobutanol production. Metab Eng 16:1-10.
    • (2013) Metab Eng , vol.16 , pp. 1-10
    • Shi, A.1    Zhu, X.2    Lu, J.3    Zhang, X.4    Ma, Y.5
  • 41
    • 78149443330 scopus 로고    scopus 로고
    • Engineering of Corynebacterium glutamicum with an NADPH-generating glycolytic pathway for L-lysine production
    • Takeno S, Murata R, Kobayashi R, Mitsuhashi S, Ikeda M. 2010. Engineering of Corynebacterium glutamicum with an NADPH-generating glycolytic pathway for L-lysine production. Appl Environ Microbiol 76(21):7154-7160.
    • (2010) Appl Environ Microbiol , vol.76 , Issue.21 , pp. 7154-7160
    • Takeno, S.1    Murata, R.2    Kobayashi, R.3    Mitsuhashi, S.4    Ikeda, M.5
  • 42
    • 68449103617 scopus 로고    scopus 로고
    • Stabilized gene duplication enables long-term selection-free heterologous pathway expression
    • Tyo K, Ajikumar PK, Stephanopoulos G. 2009. Stabilized gene duplication enables long-term selection-free heterologous pathway expression. Nat Biotech 27(8):760-765.
    • (2009) Nat Biotech , vol.27 , Issue.8 , pp. 760-765
    • Tyo, K.1    Ajikumar, P.K.2    Stephanopoulos, G.3
  • 43
    • 84863380845 scopus 로고    scopus 로고
    • Imbalance of heterologous protein folding and disulfide bond formation rates yields runaway oxidative stress
    • Tyo K, Liu Z, Petranovic D, Nielsen J. 2012. Imbalance of heterologous protein folding and disulfide bond formation rates yields runaway oxidative stress. BMC Biol 10(1):16.
    • (2012) BMC Biol , vol.10 , Issue.1 , pp. 16
    • Tyo, K.1    Liu, Z.2    Petranovic, D.3    Nielsen, J.4
  • 44
    • 84888393717 scopus 로고    scopus 로고
    • Metabolic engineering of Saccharomyces cerevisiae for biodiesel production by eliminating non-essential fatty acid utilization pathways
    • Valle-Rodríguez JO, Shi S, Siewers V, Nielsen J. 2014. Metabolic engineering of Saccharomyces cerevisiae for biodiesel production by eliminating non-essential fatty acid utilization pathways. Appl Energy 115:226-232.
    • (2014) Appl Energy , vol.115 , pp. 226-232
    • Valle-Rodríguez, J.O.1    Shi, S.2    Siewers, V.3    Nielsen, J.4
  • 46
    • 0030569739 scopus 로고    scopus 로고
    • G418 selection and stability of cloned genes integrated at chromosomal δ sequences of Saccharomyces cerevisiae
    • Wang X, Wang Z, Da Silva NA. 1996. G418 selection and stability of cloned genes integrated at chromosomal δ sequences of Saccharomyces cerevisiae. Biotechnol Bioeng 49(1):45-51.
    • (1996) Biotechnol Bioeng , vol.49 , Issue.1 , pp. 45-51
    • Wang, X.1    Wang, Z.2    Da Silva, N.A.3
  • 47
    • 79952109724 scopus 로고    scopus 로고
    • Gene copy number and polyploidy on products formation in yeast
    • Yamada R, Tanaka T, Ogino C, Kondo A. 2010. Gene copy number and polyploidy on products formation in yeast. Appl Microbiol Biotechnol 88:849-857.
    • (2010) Appl Microbiol Biotechnol , vol.88 , pp. 849-857
    • Yamada, R.1    Tanaka, T.2    Ogino, C.3    Kondo, A.4
  • 48
    • 0034894660 scopus 로고    scopus 로고
    • Overexpression of acyl-CoA binding protein and its effects on the flux of free fatty acids in McA-RH 7777 cells
    • Yang Y, Pritchard P, Bhuiyan J, Seccombe D, Moghadasian M. 2001. Overexpression of acyl-CoA binding protein and its effects on the flux of free fatty acids in McA-RH 7777 cells. Lipids 36(6):595-600.
    • (2001) Lipids , vol.36 , Issue.6 , pp. 595-600
    • Yang, Y.1    Pritchard, P.2    Bhuiyan, J.3    Seccombe, D.4    Moghadasian, M.5
  • 49
    • 77956951750 scopus 로고    scopus 로고
    • Chromosomal integration of a synthetic expression control sequence achieves poly-γ-glutamate production in a Bacillus subtilis strain
    • Yeh CM, Wang JP, Lo SC, Chan WC, Lin MY. 2010. Chromosomal integration of a synthetic expression control sequence achieves poly-γ-glutamate production in a Bacillus subtilis strain. Biotechnol Prog 26(4):1001-1007.
    • (2010) Biotechnol Prog , vol.26 , Issue.4 , pp. 1001-1007
    • Yeh, C.M.1    Wang, J.P.2    Lo, S.C.3    Chan, W.C.4    Lin, M.Y.5
  • 50
    • 81455143861 scopus 로고    scopus 로고
    • Synthesis of FAEEs from glycerol in engineered Saccharomyces cerevisiae using endogenously produced ethanol by heterologous expression of an unspecific bacterial acyltransferase
    • Yu KO, Jung J, Kim SW, Park CH, Han SO. 2011. Synthesis of FAEEs from glycerol in engineered Saccharomyces cerevisiae using endogenously produced ethanol by heterologous expression of an unspecific bacterial acyltransferase. Biotechnol Bioeng 109:110-115.
    • (2011) Biotechnol Bioeng , vol.109 , pp. 110-115
    • Yu, K.O.1    Jung, J.2    Kim, S.W.3    Park, C.H.4    Han, S.O.5
  • 51
    • 84892781979 scopus 로고    scopus 로고
    • Combinatorial engineering of mevalonate pathway for improved amorpha-4,11-diene production in budding yeast
    • Yuan J, Ching CB. 2013. Combinatorial engineering of mevalonate pathway for improved amorpha-4, 11-diene production in budding yeast. Biotechnol Bioeng 111:608-617.
    • (2013) Biotechnol Bioeng , vol.111 , pp. 608-617
    • Yuan, J.1    Ching, C.B.2
  • 52
    • 84859633048 scopus 로고    scopus 로고
    • Design of a dynamic sensor-regulator system for production of chemicals and fuels derived from fatty acids
    • Zhang F, Carothers JM, Keasling JD. 2012. Design of a dynamic sensor-regulator system for production of chemicals and fuels derived from fatty acids. Nat Biotech 30:354-359.
    • (2012) Nat Biotech , vol.30 , pp. 354-359
    • Zhang, F.1    Carothers, J.M.2    Keasling, J.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.