Heritable CRISPR/Cas9-mediated targeted integration in Xenopus tropicalis

FASEB Journal

Volumn 29, Issue 12, 2015, Pages 4914-4923

  Shi, Zhaoying ^a,b   Wang, Fengqin ^a,c   Cui, Yan ^a,d   Liu, Zhongzhen ^e   Guo, Xiaogang ^a   Zhang, Yanqi ^a,d   Deng, Yi ^b   Zhao, Hui ^e,f   Chen, Yonglong ^a,b  

^a GUANGZHOU INSTITUTES OF BIOMEDICINE AND HEALTH   (China)

^b SOUTHERN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^c ANHUI UNIVERSITY   (China)

^d UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^e Prince of Wales Hospital   (Hong Kong)

^f CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Concurrent cleavage; Homology independent; Knock in

Indexed keywords

CRISPR ASSOCIATED PROTEIN; CRISPR ASSOCIATED PROTEIN 9; DOUBLE STRANDED DNA; ENDONUCLEASE; GENOMIC DNA; GREEN FLUORESCENT PROTEIN; GUIDE RNA; MESSENGER RNA; TUBULIN; UNCLASSIFIED DRUG;

ARTICLE; CRISPR CAS SYSTEM; DIPLOIDY; DNA END JOINING REPAIR; DNA REPAIR; DNA SEQUENCE; GENOMIC FRAGMENT; GERMLINE MUTATION; INTRON; NERVE CELL DIFFERENTIATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SOUTHERN BLOTTING; STOP CODON; TADPOLE; XENOPUS TROPICALIS; ANIMAL; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; EMBRYOLOGY; GENETICS; MOLECULAR GENETICS; MUTAGENESIS; NUCLEOTIDE SEQUENCE; PLASMID; XENOPUS;

ANIMALS; BASE SEQUENCE; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS; INTRONS; MOLECULAR SEQUENCE DATA; MUTAGENESIS; PLASMIDS; XENOPUS;

EID: 84960245297     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.15-273425     Document Type: Article

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