Modeling disease mutations by gene targeting in one-cell mouse embryos

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 24, 2012, Pages 9354-9359

  Meyer, Melanie ^a,b   Ortiz, Oskar ^a   De Angelis, Martin Hrabé ^a,b   Wurst, Wolfgang ^a,b,c   Kühn, Ralf ^a,b  

^a INSTITUTE OF EPIDEMIOLOGY   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^c GERMAN CENTER FOR NEURODEGENERATIVE DISEASES DZNE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ZINC FINGER NUCLEASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING SITE; CODON; CONTROLLED STUDY; EMBRYO; EXON; FEMALE; GENE MUTATION; GENE TARGETING; MALE; MISSENSE MUTATION; MOUSE; MUTAGENESIS; MUTANT; NONHUMAN; PRIORITY JOURNAL; SEQUENCE ANALYSIS;

ANIMALS; BASE SEQUENCE; EMBRYO, MAMMALIAN; GENE TARGETING; GENETIC PREDISPOSITION TO DISEASE; GENETIC VECTORS; MICE; MOLECULAR SEQUENCE DATA; MUTATION; SEQUENCE HOMOLOGY, NUCLEIC ACID;

EID: 84862184780     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1121203109     Document Type: Article

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