Microhomology-mediated End Joining and Homologous Recombination share the initial end resection step to repair DNA double-strand breaks in mammalian cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 19, 2013, Pages 7720-7725

  Truong, Lan N ^a   Li, Yongjiang ^a   Shi, Linda Z ^b   Hwang, Patty Yi Hwa ^a   He, Jing ^a   Wang, Hailong ^a   Razavian, Niema ^a   Berns, Michael W ^b   Wu, Xiaohua ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

BLM Exo1; CtIP; DNA damage; DNA repair pathway; Genome stability

Indexed keywords

BLOOM SYNDROME HELICASE; CYCLIN DEPENDENT KINASE 2; EXONUCLEASE; EXONUCLEASE 1; HISTONE H2AX; KU ANTIGEN; MRE11 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL CYCLE S PHASE; CONTROLLED STUDY; DNA END JOINING REPAIR; DNA REPLICATION; DOUBLE STRANDED DNA BREAK; ENZYME ACTIVITY; HISTONE PHOSPHORYLATION; HUMAN; HUMAN CELL; MAMMAL CELL; MICROHOMOLOGY MEDIATED END JOINING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RECOMBINATION REPAIR; STRESS;

BLM/EXO1; CTIP; DNA DAMAGE; DNA REPAIR PATHWAY; GENOME STABILITY;

ANIMALS; ANTIGENS, NUCLEAR; CARRIER PROTEINS; CELL LINE, TUMOR; CYCLIN-DEPENDENT KINASE 2; DNA BREAKS, DOUBLE-STRANDED; DNA END-JOINING REPAIR; DNA REPAIR ENZYMES; DNA-BINDING PROTEINS; EXODEOXYRIBONUCLEASES; FIBROBLASTS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GREEN FLUORESCENT PROTEINS; HISTONES; HOMOLOGOUS RECOMBINATION; HUMANS; MEIOSIS; MICE; NUCLEAR PROTEINS; RECQ HELICASES; S PHASE;

EID: 84877321963     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1213431110     Document Type: Article

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