-
1
-
-
60149092294
-
Severely dystrophic axons at amyloid plaques remain continuous and connected to viable cell bodies
-
PID: 19059977
-
Adalbert R, Nogradi A, Babetto E, Janeckova L, Walker SA, Kerschensteiner M, Misgeld T, Coleman MP (2009) Severely dystrophic axons at amyloid plaques remain continuous and connected to viable cell bodies. Brain 132:402–416. doi:10.1093/brain/awn312
-
(2009)
Brain
, vol.132
, pp. 402-416
-
-
Adalbert, R.1
Nogradi, A.2
Babetto, E.3
Janeckova, L.4
Walker, S.A.5
Kerschensteiner, M.6
Misgeld, T.7
Coleman, M.P.8
-
2
-
-
84893687955
-
In vivo type 1 cannabinoid receptor availability in Alzheimer’s disease
-
COI: 1:CAS:528:DC%2BC3sXhslWlt7%2FP, PID: 24189376
-
Ahmad R, Goffin K, Van den Stock J, De Winter FL, Cleeren E, Bormans G, Tournoy J, Persoons P, Van Laere K, Vandenbulcke M (2014) In vivo type 1 cannabinoid receptor availability in Alzheimer’s disease. Eur Neuropsychopharmacol 24:242–250. doi:10.1016/j.euroneuro.2013.10.002
-
(2014)
Eur Neuropsychopharmacol
, vol.24
, pp. 242-250
-
-
Ahmad, R.1
Goffin, K.2
Van den Stock, J.3
De Winter, F.L.4
Cleeren, E.5
Bormans, G.6
Tournoy, J.7
Persoons, P.8
Van Laere, K.9
Vandenbulcke, M.10
-
3
-
-
47049111840
-
Stereologic estimates of total spinophilin-immunoreactive spine number in area 9 and the CA1 field: relationship with the progression of Alzheimer’s disease
-
COI: 1:CAS:528:DC%2BD1cXoslCls7s%3D, PID: 17420070
-
Akram A, Christoffel D, Rocher AB, Bouras C, Kovari E, Perl DP, Morrison JH, Herrmann FR, Haroutunian V, Giannakopoulos P et al (2008) Stereologic estimates of total spinophilin-immunoreactive spine number in area 9 and the CA1 field: relationship with the progression of Alzheimer’s disease. Neurobiol Aging 29:1296–1307. doi:10.1016/j.neurobiolaging.2007.03.007
-
(2008)
Neurobiol Aging
, vol.29
, pp. 1296-1307
-
-
Akram, A.1
Christoffel, D.2
Rocher, A.B.3
Bouras, C.4
Kovari, E.5
Perl, D.P.6
Morrison, J.H.7
Herrmann, F.R.8
Haroutunian, V.9
Giannakopoulos, P.10
-
5
-
-
68849122533
-
Age-dependent impairment of spine morphology and synaptic plasticity in hippocampal CA1 neurons of a presenilin 1 transgenic mouse model of Alzheimer’s disease
-
COI: 1:CAS:528:DC%2BD1MXhtVWktrrO, PID: 19675248
-
Auffret A, Gautheron V, Repici M, Kraftsik R, Mount HT, Mariani J, Rovira C (2009) Age-dependent impairment of spine morphology and synaptic plasticity in hippocampal CA1 neurons of a presenilin 1 transgenic mouse model of Alzheimer’s disease. J Neurosci 29:10144–10152. doi:10.1523/jneurosci.1856-09.2009
-
(2009)
J Neurosci
, vol.29
, pp. 10144-10152
-
-
Auffret, A.1
Gautheron, V.2
Repici, M.3
Kraftsik, R.4
Mount, H.T.5
Mariani, J.6
Rovira, C.7
-
6
-
-
0030610645
-
Microglial activation by Alzheimer amyloid precursor protein and modulation by apolipoprotein E
-
COI: 1:CAS:528:DyaK2sXlslagsrY%3D, PID: 9278049
-
Barger SW, Harmon AD (1997) Microglial activation by Alzheimer amyloid precursor protein and modulation by apolipoprotein E. Nature 388:878–881
-
(1997)
Nature
, vol.388
, pp. 878-881
-
-
Barger, S.W.1
Harmon, A.D.2
-
7
-
-
0034058834
-
Functional phenotype in transgenic mice expressing mutant human presenilin-1
-
COI: 1:CAS:528:DC%2BD3cXislaqtbg%3D, PID: 10783295
-
Barrow PA, Empson RM, Gladwell SJ, Anderson CM, Killick R, Yu X, Jefferys JG, Duff K (2000) Functional phenotype in transgenic mice expressing mutant human presenilin-1. Neurobiol Dis 7:119–126. doi:10.1006/nbdi.1999.0276
-
(2000)
Neurobiol Dis
, vol.7
, pp. 119-126
-
-
Barrow, P.A.1
Empson, R.M.2
Gladwell, S.J.3
Anderson, C.M.4
Killick, R.5
Yu, X.6
Jefferys, J.G.7
Duff, K.8
-
8
-
-
62149119762
-
Akt/GSK3 signaling in the action of psychotropic drugs
-
COI: 1:CAS:528:DC%2BD1MXisV2jsb0%3D, PID: 18928402
-
Beaulieu J-M, Gainetdinov RR, Caron MG (2009) Akt/GSK3 signaling in the action of psychotropic drugs. Annu Rev Pharmacol Toxicol 49:327–347. doi:10.1146/annurev.pharmtox.011008.145634
-
(2009)
Annu Rev Pharmacol Toxicol
, vol.49
, pp. 327-347
-
-
Beaulieu, J.-M.1
Gainetdinov, R.R.2
Caron, M.G.3
-
9
-
-
9644278035
-
Synaptic structural abnormalities in the Ts65Dn mouse model of Down Syndrome
-
PID: 15515178
-
Belichenko PV, Masliah E, Kleschevnikov AM, Villar AJ, Epstein CJ, Salehi A, Mobley WC (2004) Synaptic structural abnormalities in the Ts65Dn mouse model of Down Syndrome. J Comp Neurol 480:281–298. doi:10.1002/cne.20337
-
(2004)
J Comp Neurol
, vol.480
, pp. 281-298
-
-
Belichenko, P.V.1
Masliah, E.2
Kleschevnikov, A.M.3
Villar, A.J.4
Epstein, C.J.5
Salehi, A.6
Mobley, W.C.7
-
10
-
-
7244242262
-
Induction of inflammatory mediators and microglial activation in mice transgenic for mutant human P301S tau protein
-
COI: 1:CAS:528:DC%2BD2cXhtVCgsb%2FE, PID: 15509534
-
Bellucci A, Westwood AJ, Ingram E, Casamenti F, Goedert M, Spillantini MG (2004) Induction of inflammatory mediators and microglial activation in mice transgenic for mutant human P301S tau protein. Am J Pathol 165:1643–1652
-
(2004)
Am J Pathol
, vol.165
, pp. 1643-1652
-
-
Bellucci, A.1
Westwood, A.J.2
Ingram, E.3
Casamenti, F.4
Goedert, M.5
Spillantini, M.G.6
-
11
-
-
84884635054
-
Promiscuous Alzheimer’s amyloid: yet another partner
-
PID: 24052299
-
Benilova I, De Strooper B (2013) Promiscuous Alzheimer’s amyloid: yet another partner. Science 341:1354–1355. doi:10.1126/science.1244166
-
(2013)
Science
, vol.341
, pp. 1354-1355
-
-
Benilova, I.1
De Strooper, B.2
-
12
-
-
84857642949
-
The toxic A[beta] oligomer and Alzheimer’s disease: an emperor in need of clothes
-
COI: 1:CAS:528:DC%2BC38XhtlOltrc%3D, PID: 22286176
-
Benilova I, Karran E, De Strooper B (2012) The toxic A[beta] oligomer and Alzheimer’s disease: an emperor in need of clothes. Nat Neurosci 15:349–357
-
(2012)
Nat Neurosci
, vol.15
, pp. 349-357
-
-
Benilova, I.1
Karran, E.2
De Strooper, B.3
-
13
-
-
14444285507
-
Clinicopathologic studies in cognitively healthy aging and Alzheimer’s disease: relation of histologic markers to dementia severity, age, sex, and apolipoprotein E genotype
-
COI: 1:STN:280:DyaK1c7nvVyhug%3D%3D, PID: 9520006
-
Berg L, McKeel DW Jr, Miller JP, Storandt M, Rubin EH, Morris JC, Baty J, Coats M, Norton J, Goate AM et al (1998) Clinicopathologic studies in cognitively healthy aging and Alzheimer’s disease: relation of histologic markers to dementia severity, age, sex, and apolipoprotein E genotype. Arch Neurol 55:326–335
-
(1998)
Arch Neurol
, vol.55
, pp. 326-335
-
-
Berg, L.1
McKeel, D.W.2
Miller, J.P.3
Storandt, M.4
Rubin, E.H.5
Morris, J.C.6
Baty, J.7
Coats, M.8
Norton, J.9
Goate, A.M.10
-
14
-
-
77957927865
-
The genetics of Alzheimer disease: back to the future
-
COI: 1:CAS:528:DC%2BC3cXhtlSmtr%2FN, PID: 20955934
-
Bertram L, Lill CM, Tanzi RE (2010) The genetics of Alzheimer disease: back to the future. Neuron 68:270–281
-
(2010)
Neuron
, vol.68
, pp. 270-281
-
-
Bertram, L.1
Lill, C.M.2
Tanzi, R.E.3
-
15
-
-
77957321869
-
Regulation of tau pathology by the microglial fractalkine receptor
-
COI: 1:CAS:528:DC%2BC3cXht1Cgu7zP, PID: 20920788
-
Bhaskar K, Konerth M, Kokiko-Cochran ON, Cardona A, Ransohoff RM, Lamb BT (2010) Regulation of tau pathology by the microglial fractalkine receptor. Neuron 68:19–31
-
(2010)
Neuron
, vol.68
, pp. 19-31
-
-
Bhaskar, K.1
Konerth, M.2
Kokiko-Cochran, O.N.3
Cardona, A.4
Ransohoff, R.M.5
Lamb, B.T.6
-
16
-
-
22144462135
-
Neurotoxic protein oligomers–what you see is not always what you get
-
PID: 16011984
-
Bitan G, Fradinger EA, Spring SM, Teplow DB (2005) Neurotoxic protein oligomers–what you see is not always what you get. Amyloid 12:88–95. doi:10.1080/13506120500106958
-
(2005)
Amyloid
, vol.12
, pp. 88-95
-
-
Bitan, G.1
Fradinger, E.A.2
Spring, S.M.3
Teplow, D.B.4
-
17
-
-
84878351215
-
Amyloid plaque formation precedes dendritic spine loss
-
PID: 22993126
-
Bittner T, Burgold S, Dorostkar M, Fuhrmann M, Wegenast-Braun B, Schmidt B, Kretzschmar H, Herms J (2012) Amyloid plaque formation precedes dendritic spine loss. Acta Neuropathol 124:797–807. doi:10.1007/s00401-012-1047-8
-
(2012)
Acta Neuropathol
, vol.124
, pp. 797-807
-
-
Bittner, T.1
Burgold, S.2
Dorostkar, M.3
Fuhrmann, M.4
Wegenast-Braun, B.5
Schmidt, B.6
Kretzschmar, H.7
Herms, J.8
-
18
-
-
69049091954
-
Gamma-secretase inhibition reduces spine density in vivo via an amyloid precursor protein-dependent pathway
-
COI: 1:CAS:528:DC%2BD1MXhtVKqt7fL, PID: 19692615
-
Bittner T, Fuhrmann M, Burgold S, Jung CK, Volbracht C, Steiner H, Mitteregger G, Kretzschmar HA, Haass C, Herms J (2009) Gamma-secretase inhibition reduces spine density in vivo via an amyloid precursor protein-dependent pathway. J Neurosci 29:10405–10409
-
(2009)
J Neurosci
, vol.29
, pp. 10405-10409
-
-
Bittner, T.1
Fuhrmann, M.2
Burgold, S.3
Jung, C.K.4
Volbracht, C.5
Steiner, H.6
Mitteregger, G.7
Kretzschmar, H.A.8
Haass, C.9
Herms, J.10
-
19
-
-
78649498235
-
Multiple events lead to dendritic spine loss in triple transgenic Alzheimer’s disease mice
-
PID: 21103384
-
Bittner T, Fuhrmann M, Burgold S, Ochs SM, Hoffmann N, Mitteregger G, Kretzschmar H, LaFerla FM, Herms J (2010) Multiple events lead to dendritic spine loss in triple transgenic Alzheimer’s disease mice. PLoS One 5:e15477
-
(2010)
PLoS One
, vol.5
, pp. 15477
-
-
Bittner, T.1
Fuhrmann, M.2
Burgold, S.3
Ochs, S.M.4
Hoffmann, N.5
Mitteregger, G.6
Kretzschmar, H.7
LaFerla, F.M.8
Herms, J.9
-
20
-
-
84904460208
-
Accumulation of intraneuronal amyloid-beta is common in normal brain
-
COI: 1:CAS:528:DC%2BC2cXnt1emt7s%3D, PID: 24597504
-
Blair JA, Siedlak SL, Wolfram JA, Nunomura A, Castellani RJ, Ferreira ST, Klein WL, Wang Y, Casadesus G, Smith MA et al (2014) Accumulation of intraneuronal amyloid-beta is common in normal brain. Curr Alzheimer Res 11:317–324
-
(2014)
Curr Alzheimer Res
, vol.11
, pp. 317-324
-
-
Blair, J.A.1
Siedlak, S.L.2
Wolfram, J.A.3
Nunomura, A.4
Castellani, R.J.5
Ferreira, S.T.6
Klein, W.L.7
Wang, Y.8
Casadesus, G.9
Smith, M.A.10
-
21
-
-
80055026234
-
Abnormal tau phosphorylation in the thorny excrescences of CA3 hippocampal neurons in patients with Alzheimer’s disease
-
COI: 1:CAS:528:DC%2BC3MXhsVSqt73N, PID: 21677375
-
Blazquez-Llorca L, Garcia-Marin V, Merino-Serrais P, Avila J, DeFelipe J (2011) Abnormal tau phosphorylation in the thorny excrescences of CA3 hippocampal neurons in patients with Alzheimer’s disease. J Alzheimers Dis 26:683–698. doi:10.3233/jad-2011-110659
-
(2011)
J Alzheimers Dis
, vol.26
, pp. 683-698
-
-
Blazquez-Llorca, L.1
Garcia-Marin, V.2
Merino-Serrais, P.3
Avila, J.4
DeFelipe, J.5
-
22
-
-
84922569176
-
Mutant huntingtin alters Tau phosphorylation and subcellular distribution
-
PID: 25143394
-
Blum D, Herrera F, Francelle L, Mendes T, Basquin M, Obriot H, Demeyer D, Sergeant N, Gerhardt E, Brouillet E et al (2014) Mutant huntingtin alters Tau phosphorylation and subcellular distribution. Hum Mol Genet. doi:10.1093/hmg/ddu421
-
(2014)
Hum Mol Genet
-
-
Blum, D.1
Herrera, F.2
Francelle, L.3
Mendes, T.4
Basquin, M.5
Obriot, H.6
Demeyer, D.7
Sergeant, N.8
Gerhardt, E.9
Brouillet, E.10
-
23
-
-
84879217258
-
A ‘danse macabre’: tau and Fyn in STEP with amyloid beta to facilitate induction of synaptic depression and excitotoxicity
-
PID: 23773061
-
Boehm J (2013) A ‘danse macabre’: tau and Fyn in STEP with amyloid beta to facilitate induction of synaptic depression and excitotoxicity. Eur J Neurosci 37:1925–1930. doi:10.1111/ejn.12251
-
(2013)
Eur J Neurosci
, vol.37
, pp. 1925-1930
-
-
Boehm, J.1
-
24
-
-
78649417803
-
Activation of extrasynaptic, but not synaptic, NMDA receptors modifies amyloid precursor protein expression pattern and increases amyloid-{beta} production
-
COI: 1:CAS:528:DC%2BC3cXhsFCiurbL, PID: 21106831
-
Bordji K, Becerril-Ortega J, Nicole O, Buisson A (2010) Activation of extrasynaptic, but not synaptic, NMDA receptors modifies amyloid precursor protein expression pattern and increases amyloid-{beta} production. J Neurosci 30:15927–15942. doi:10.1523/jneurosci.3021-10.2010
-
(2010)
J Neurosci
, vol.30
, pp. 15927-15942
-
-
Bordji, K.1
Becerril-Ortega, J.2
Nicole, O.3
Buisson, A.4
-
25
-
-
33749150163
-
Staging of Alzheimer disease-associated neurofibrillary pathology using paraffin sections and immunocytochemistry
-
PID: 16906426
-
Braak H, Alafuzoff I, Arzberger T, Kretzschmar H, Del Tredici K (2006) Staging of Alzheimer disease-associated neurofibrillary pathology using paraffin sections and immunocytochemistry. Acta Neuropathol 112:389–404. doi:10.1007/s00401-006-0127-z
-
(2006)
Acta Neuropathol
, vol.112
, pp. 389-404
-
-
Braak, H.1
Alafuzoff, I.2
Arzberger, T.3
Kretzschmar, H.4
Del Tredici, K.5
-
26
-
-
0025863618
-
Neuropathological stageing of Alzheimer-related changes
-
COI: 1:STN:280:DyaK387gtFOiug%3D%3D, PID: 1759558
-
Braak H, Braak E (1991) Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol 82:239–259
-
(1991)
Acta Neuropathol
, vol.82
, pp. 239-259
-
-
Braak, H.1
Braak, E.2
-
27
-
-
80054904670
-
Stages of the pathologic process in Alzheimer disease: age categories from 1 to 100 years
-
COI: 1:CAS:528:DC%2BC3MXhtlChs7bJ, PID: 22002422
-
Braak H, Thal DR, Ghebremedhin E, Del Tredici K (2011) Stages of the pathologic process in Alzheimer disease: age categories from 1 to 100 years. J Neuropathol Exp Neurol 70:960–969. doi:10.1097/NEN.0b013e318232a379
-
(2011)
J Neuropathol Exp Neurol
, vol.70
, pp. 960-969
-
-
Braak, H.1
Thal, D.R.2
Ghebremedhin, E.3
Del Tredici, K.4
-
28
-
-
84872620881
-
NMDA receptor dysfunction contributes to impaired brain-derived neurotrophic factor-induced facilitation of hippocampal synaptic transmission in a Tau transgenic model
-
COI: 1:CAS:528:DC%2BC3sXjt1Wnsrg%3D, PID: 23082852
-
Burnouf S, Martire A, Derisbourg M, Laurent C, Belarbi K, Leboucher A, Fernandez-Gomez FJ, Troquier L, Eddarkaoui S, Grosjean ME et al (2013) NMDA receptor dysfunction contributes to impaired brain-derived neurotrophic factor-induced facilitation of hippocampal synaptic transmission in a Tau transgenic model. Aging Cell 12:11–23. doi:10.1111/acel.12018
-
(2013)
Aging Cell
, vol.12
, pp. 11-23
-
-
Burnouf, S.1
Martire, A.2
Derisbourg, M.3
Laurent, C.4
Belarbi, K.5
Leboucher, A.6
Fernandez-Gomez, F.J.7
Troquier, L.8
Eddarkaoui, S.9
Grosjean, M.E.10
-
29
-
-
84861844315
-
Critical role of soluble amyloid-β for early hippocampal hyperactivity in a mouse model of Alzheimer’s disease
-
COI: 1:CAS:528:DC%2BC38XoslCjsbw%3D, PID: 22592800
-
Busche MA, Chen X, Henning HA, Reichwald J, Staufenbiel M, Sakmann B, Konnerth A (2012) Critical role of soluble amyloid-β for early hippocampal hyperactivity in a mouse model of Alzheimer’s disease. Proc Natl Acad Sci 109:8740–8745. doi:10.1073/pnas.1206171109
-
(2012)
Proc Natl Acad Sci
, vol.109
, pp. 8740-8745
-
-
Busche, M.A.1
Chen, X.2
Henning, H.A.3
Reichwald, J.4
Staufenbiel, M.5
Sakmann, B.6
Konnerth, A.7
-
30
-
-
52249115856
-
Clusters of hyperactive neurons near amyloid plaques in a mouse model of Alzheimer’s disease
-
COI: 1:CAS:528:DC%2BD1cXhtFamtrvJ, PID: 18802001
-
Busche MA, Eichhoff G, Adelsberger H, Abramowski D, Wiederhold K-H, Haass C, Staufenbiel M, Konnerth A, Garaschuk O (2008) Clusters of hyperactive neurons near amyloid plaques in a mouse model of Alzheimer’s disease. Science 321:1686–1689. doi:10.1126/science.1162844
-
(2008)
Science
, vol.321
, pp. 1686-1689
-
-
Busche, M.A.1
Eichhoff, G.2
Adelsberger, H.3
Abramowski, D.4
Wiederhold, K.-H.5
Haass, C.6
Staufenbiel, M.7
Konnerth, A.8
Garaschuk, O.9
-
31
-
-
84856457372
-
Traumatic brain injury causes an FK506-sensitive loss and an overgrowth of dendritic spines in rat forebrain
-
Campbell JN, Register D, Churn SB (2011) Traumatic brain injury causes an FK506-sensitive loss and an overgrowth of dendritic spines in rat forebrain. J Neurotrauma 29:201–217. doi:10.1089/neu.2011.1761
-
(2011)
J Neurotrauma
, vol.29
, pp. 201-217
-
-
Campbell, J.N.1
Register, D.2
Churn, S.B.3
-
32
-
-
84866111331
-
Aβ alters the connectivity of olfactory neurons in the absence of amyloid plaques in vivo
-
PID: 22910355
-
Cao L, Schrank BR, Rodriguez S, Benz EG, Moulia TW, Rickenbacher GT, Gomez AC, Levites Y, Edwards SR, Golde TE et al (2012) Aβ alters the connectivity of olfactory neurons in the absence of amyloid plaques in vivo. Nat Commun 3:1009. doi:10.1038/ncomms2013
-
(2012)
Nat Commun
, vol.3
, pp. 1009
-
-
Cao, L.1
Schrank, B.R.2
Rodriguez, S.3
Benz, E.G.4
Moulia, T.W.5
Rickenbacher, G.T.6
Gomez, A.C.7
Levites, Y.8
Edwards, S.R.9
Golde, T.E.10
-
33
-
-
84897954670
-
The complexities of the pathology–pathogenesis relationship in Alzheimer disease
-
COI: 1:CAS:528:DC%2BC2cXhs1KntLw%3D, PID: 24447936
-
Castellani RJ, Perry G (2014) The complexities of the pathology–pathogenesis relationship in Alzheimer disease. Biochem Pharmacol 88:671–676. doi:10.1016/j.bcp.2014.01.009
-
(2014)
Biochem Pharmacol
, vol.88
, pp. 671-676
-
-
Castellani, R.J.1
Perry, G.2
-
34
-
-
79959772357
-
Human apoE isoforms differentially regulate brain amyloid-beta peptide clearance
-
COI: 1:CAS:528:DC%2BC3MXhtFOisL7J, PID: 21715678
-
Castellano JM, Kim J, Stewart FR, Jiang H, DeMattos RB, Patterson BW, Fagan AM, Morris JC, Mawuenyega KG, Cruchaga C et al (2011) Human apoE isoforms differentially regulate brain amyloid-beta peptide clearance. Sci Transl Med 3:89ra57. doi:10.1126/scitranslmed.3002156
-
(2011)
Sci Transl Med
, vol.3
, pp. 57
-
-
Castellano, J.M.1
Kim, J.2
Stewart, F.R.3
Jiang, H.4
DeMattos, R.B.5
Patterson, B.W.6
Fagan, A.M.7
Morris, J.C.8
Mawuenyega, K.G.9
Cruchaga, C.10
-
35
-
-
84925845438
-
Tau immunotherapy modulates both pathological tau and upstream amyloid pathology in an Alzheimer’s disease mouse model
-
PID: 25810517
-
Castillo-Carranza DL, Guerrero-Munoz MJ, Sengupta U, Hernandez C, Barrett AD, Dineley K, Kayed R (2015) Tau immunotherapy modulates both pathological tau and upstream amyloid pathology in an Alzheimer’s disease mouse model. J Neurosci 35:4857–4868. doi:10.1523/jneurosci.4989-14.2015
-
(2015)
J Neurosci
, vol.35
, pp. 4857-4868
-
-
Castillo-Carranza, D.L.1
Guerrero-Munoz, M.J.2
Sengupta, U.3
Hernandez, C.4
Barrett, A.D.5
Dineley, K.6
Kayed, R.7
-
36
-
-
63849213783
-
Inflammation triggers synaptic alteration and degeneration in experimental autoimmune encephalomyelitis
-
COI: 1:CAS:528:DC%2BD1MXjs1Wmur4%3D, PID: 19295150
-
Centonze D, Muzio L, Rossi S, Cavasinni F, De Chiara V, Bergami A, Musella A, D’Amelio M, Cavallucci V, Martorana A et al (2009) Inflammation triggers synaptic alteration and degeneration in experimental autoimmune encephalomyelitis. J Neurosci 29:3442–3452. doi:10.1523/jneurosci.5804-08.2009
-
(2009)
J Neurosci
, vol.29
, pp. 3442-3452
-
-
Centonze, D.1
Muzio, L.2
Rossi, S.3
Cavasinni, F.4
De Chiara, V.5
Bergami, A.6
Musella, A.7
D’Amelio, M.8
Cavallucci, V.9
Martorana, A.10
-
37
-
-
68049134265
-
Deviant ryanodine receptor-mediated calcium release resets synaptic homeostasis in presymptomatic 3xTg-AD mice
-
COI: 1:CAS:528:DC%2BD1MXpsFOntrc%3D, PID: 19641109
-
Chakroborty S, Goussakov I, Miller MB, Stutzmann GE (2009) Deviant ryanodine receptor-mediated calcium release resets synaptic homeostasis in presymptomatic 3xTg-AD mice. J Neurosci 29:9458–9470. doi:10.1523/jneurosci.2047-09.2009
-
(2009)
J Neurosci
, vol.29
, pp. 9458-9470
-
-
Chakroborty, S.1
Goussakov, I.2
Miller, M.B.3
Stutzmann, G.E.4
-
38
-
-
79960626655
-
Early calcium dysregulation in Alzheimer’s disease: setting the stage for synaptic dysfunction
-
COI: 1:CAS:528:DC%2BC3MXptlyjtb0%3D, PID: 21786198
-
Chakroborty S, Stutzmann G (2011) Early calcium dysregulation in Alzheimer’s disease: setting the stage for synaptic dysfunction. Sci China Life Sci 54:752–762. doi:10.1007/s11427-011-4205-7
-
(2011)
Sci China Life Sci
, vol.54
, pp. 752-762
-
-
Chakroborty, S.1
Stutzmann, G.2
-
39
-
-
9144272296
-
Aggressive amyloidosis in mice expressing human amyloid peptides with the Arctic mutation
-
COI: 1:CAS:528:DC%2BD2cXptVOgtr4%3D, PID: 15502844
-
Cheng IH, Palop JJ, Esposito LA, Bien-Ly N, Yan F, Mucke L (2004) Aggressive amyloidosis in mice expressing human amyloid peptides with the Arctic mutation. Nat Med 10:1190–1192. doi:10.1038/nm1123
-
(2004)
Nat Med
, vol.10
, pp. 1190-1192
-
-
Cheng, I.H.1
Palop, J.J.2
Esposito, L.A.3
Bien-Ly, N.4
Yan, F.5
Mucke, L.6
-
40
-
-
77953644150
-
Gain-of-function enhancement of IP3 receptor modal gating by familial Alzheimer’s disease-linked presenilin mutants in human cells and mouse neurons
-
PID: 20332427
-
Cheung KH, Mei L, Mak DO, Hayashi I, Iwatsubo T, Kang DE, Foskett JK (2010) Gain-of-function enhancement of IP3 receptor modal gating by familial Alzheimer’s disease-linked presenilin mutants in human cells and mouse neurons. Sci Signal 3:ra22. doi:10.1126/scisignal.2000818
-
(2010)
Sci Signal
, vol.3
, pp. 22
-
-
Cheung, K.H.1
Mei, L.2
Mak, D.O.3
Hayashi, I.4
Iwatsubo, T.5
Kang, D.E.6
Foskett, J.K.7
-
41
-
-
45249117227
-
Mechanism of Ca2+ disruption in Alzheimer’s disease by presenilin regulation of InsP3 receptor channel gating
-
COI: 1:CAS:528:DC%2BD1cXotFyrsLw%3D, PID: 18579078
-
Cheung KH, Shineman D, Muller M, Cardenas C, Mei L, Yang J, Tomita T, Iwatsubo T, Lee VM, Foskett JK (2008) Mechanism of Ca2+ disruption in Alzheimer’s disease by presenilin regulation of InsP3 receptor channel gating. Neuron 58:871–883. doi:10.1016/j.neuron.2008.04.015
-
(2008)
Neuron
, vol.58
, pp. 871-883
-
-
Cheung, K.H.1
Shineman, D.2
Muller, M.3
Cardenas, C.4
Mei, L.5
Yang, J.6
Tomita, T.7
Iwatsubo, T.8
Lee, V.M.9
Foskett, J.K.10
-
42
-
-
0026778684
-
Three-dimensional analysis of the structure and composition of CA3 branched dendritic spines and their synaptic relationships with mossy fiber boutons in the rat hippocampus
-
COI: 1:STN:280:DyaK3s%2FpsVekuw%3D%3D, PID: 1460112
-
Chicurel ME, Harris KM (1992) Three-dimensional analysis of the structure and composition of CA3 branched dendritic spines and their synaptic relationships with mossy fiber boutons in the rat hippocampus. J Comp Neurol 325:169–182. doi:10.1002/cne.903250204
-
(1992)
J Comp Neurol
, vol.325
, pp. 169-182
-
-
Chicurel, M.E.1
Harris, K.M.2
-
43
-
-
0035877756
-
Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695
-
COI: 1:CAS:528:DC%2BD3MXksFGlu7c%3D, PID: 11279122
-
Chishti MA, Yang DS, Janus C, Phinney AL, Horne P, Pearson J, Strome R, Zuker N, Loukides J, French J et al (2001) Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695. J Biol Chem 276:21562–21570. doi:10.1074/jbc.M100710200
-
(2001)
J Biol Chem
, vol.276
, pp. 21562-21570
-
-
Chishti, M.A.1
Yang, D.S.2
Janus, C.3
Phinney, A.L.4
Horne, P.5
Pearson, J.6
Strome, R.7
Zuker, N.8
Loukides, J.9
French, J.10
-
44
-
-
84904574292
-
Axonal degeneration in an Alzheimer mouse model is PS1 gene dose dependent and linked to intraneuronal Abeta accumulation
-
PID: 25018730
-
Christensen DZ, Huettenrauch M, Mitkovski M, Pradier L, Wirths O (2014) Axonal degeneration in an Alzheimer mouse model is PS1 gene dose dependent and linked to intraneuronal Abeta accumulation. Front Aging Neurosci 6:139. doi:10.3389/fnagi.2014.00139
-
(2014)
Front Aging Neurosci
, vol.6
, pp. 139
-
-
Christensen, D.Z.1
Huettenrauch, M.2
Mitkovski, M.3
Pradier, L.4
Wirths, O.5
-
45
-
-
29144487182
-
Synaptic activity regulates interstitial fluid amyloid-β levels in vivo
-
COI: 1:CAS:528:DC%2BD28XivFSksg%3D%3D, PID: 16364896
-
Cirrito JR, Yamada KA, Finn MB, Sloviter RS, Bales KR, May PC, Schoepp DD, Paul SM, Mennerick S, Holtzman DM (2005) Synaptic activity regulates interstitial fluid amyloid-β levels in vivo. Neuron 48:913–922. doi:10.1016/j.neuron.2005.10.028
-
(2005)
Neuron
, vol.48
, pp. 913-922
-
-
Cirrito, J.R.1
Yamada, K.A.2
Finn, M.B.3
Sloviter, R.S.4
Bales, K.R.5
May, P.C.6
Schoepp, D.D.7
Paul, S.M.8
Mennerick, S.9
Holtzman, D.M.10
-
46
-
-
84878723720
-
Brain homogenates from human tauopathies induce tau inclusions in mouse brain
-
COI: 1:CAS:528:DC%2BC3sXhtFGrtrbO, PID: 23690619
-
Clavaguera F, Akatsu H, Fraser G, Crowther RA, Frank S, Hench J, Probst A, Winkler DT, Reichwald J, Staufenbiel M et al (2013) Brain homogenates from human tauopathies induce tau inclusions in mouse brain. Proc Natl Acad Sci 110:9535–9540. doi:10.1073/pnas.1301175110
-
(2013)
Proc Natl Acad Sci
, vol.110
, pp. 9535-9540
-
-
Clavaguera, F.1
Akatsu, H.2
Fraser, G.3
Crowther, R.A.4
Frank, S.5
Hench, J.6
Probst, A.7
Winkler, D.T.8
Reichwald, J.9
Staufenbiel, M.10
-
47
-
-
0014258374
-
Evironmental effects on cortical dendritic fields. I. Rearing in the dark
-
COI: 1:STN:280:DyaF1c3otleqtg%3D%3D, PID: 5656134
-
Coleman PD, Riesen AH (1968) Evironmental effects on cortical dendritic fields. I. Rearing in the dark. J Anat 102:363–374
-
(1968)
J Anat
, vol.102
, pp. 363-374
-
-
Coleman, P.D.1
Riesen, A.H.2
-
48
-
-
78650659370
-
Caspase-3 triggers early synaptic dysfunction in a mouse model of Alzheimer’s disease
-
PID: 21151119
-
D’Amelio M, Cavallucci V, Middei S, Marchetti C, Pacioni S, Ferri A, Diamantini A, De Zio D, Carrara P, Battistini L et al (2011) Caspase-3 triggers early synaptic dysfunction in a mouse model of Alzheimer’s disease. Nat Neurosci 14:69–76
-
(2011)
Nat Neurosci
, vol.14
, pp. 69-76
-
-
D’Amelio, M.1
Cavallucci, V.2
Middei, S.3
Marchetti, C.4
Pacioni, S.5
Ferri, A.6
Diamantini, A.7
De Zio, D.8
Carrara, P.9
Battistini, L.10
-
49
-
-
40449122005
-
Multiple sclerosis and Alzheimer’s disease
-
PID: 17924575
-
Dal Bianco A, Bradl M, Frischer J, Kutzelnigg A, Jellinger K, Lassmann H (2008) Multiple sclerosis and Alzheimer’s disease. Ann Neurol 63:174–183. doi:10.1002/ana.21240
-
(2008)
Ann Neurol
, vol.63
, pp. 174-183
-
-
Dal Bianco, A.1
Bradl, M.2
Frischer, J.3
Kutzelnigg, A.4
Jellinger, K.5
Lassmann, H.6
-
50
-
-
84901939005
-
Altered function of hippocampal CA1 pyramidal neurons in the rTg4510 mouse model of tauopathy
-
COI: 1:CAS:528:DC%2BC2cXltlaksbo%3D, PID: 24448785
-
Dalby NO, Volbracht C, Helboe L, Larsen PH, Jensen HS, Egebjerg J, Elvang AB (2014) Altered function of hippocampal CA1 pyramidal neurons in the rTg4510 mouse model of tauopathy. J Alzheimers Dis 40:429–442. doi:10.3233/jad-131358
-
(2014)
J Alzheimers Dis
, vol.40
, pp. 429-442
-
-
Dalby, N.O.1
Volbracht, C.2
Helboe, L.3
Larsen, P.H.4
Jensen, H.S.5
Egebjerg, J.6
Elvang, A.B.7
-
51
-
-
77951540816
-
Caspase activation precedes and leads to tangles
-
PID: 20357768
-
de Calignon A, Fox LM, Pitstick R, Carlson GA, Bacskai BJ, Spires-Jones TL, Hyman BT (2010) Caspase activation precedes and leads to tangles. Nature 464:1201–1204
-
(2010)
Nature
, vol.464
, pp. 1201-1204
-
-
de Calignon, A.1
Fox, L.M.2
Pitstick, R.3
Carlson, G.A.4
Bacskai, B.J.5
Spires-Jones, T.L.6
Hyman, B.T.7
-
52
-
-
84857275902
-
Propagation of Tau pathology in a model of early Alzheimer’s disease
-
PID: 22365544
-
de Calignon A, Polydoro M, Suárez-Calvet M, William C, Adamowicz David H, Kopeikina Kathy J, Pitstick R, Sahara N, Ashe Karen H, Carlson George A et al (2012) Propagation of Tau pathology in a model of early Alzheimer’s disease. Neuron 73:685–697
-
(2012)
Neuron
, vol.73
, pp. 685-697
-
-
de Calignon, A.1
Polydoro, M.2
Suárez-Calvet, M.3
William, C.4
Adamowicz David, H.5
Kopeikina Kathy, J.6
Pitstick, R.7
Sahara, N.8
Ashe Karen, H.9
Carlson George, A.10
-
53
-
-
0025269152
-
Synapse loss in frontal cortex biopsies in Alzheimer’s disease: correlation with cognitive severity
-
COI: 1:STN:280:DyaK3c3pslGntg%3D%3D, PID: 2360787
-
DeKosky ST, Scheff SW (1990) Synapse loss in frontal cortex biopsies in Alzheimer’s disease: correlation with cognitive severity. Ann Neurol 27:457–464. doi:10.1002/ana.410270502
-
(1990)
Ann Neurol
, vol.27
, pp. 457-464
-
-
DeKosky, S.T.1
Scheff, S.W.2
-
54
-
-
84872144291
-
A plaque-specific antibody clears existing beta-amyloid plaques in Alzheimer’s disease mice
-
COI: 1:CAS:528:DC%2BC38Xhsl2isrvN, PID: 23217740
-
DeMattos Ronald B, Lu J, Tang Y, Racke Margaret M, DeLong Cindy A, Tzaferis John A, Hole Justin T, Forster Beth M, McDonnell Peter C, Liu F et al (2012) A plaque-specific antibody clears existing beta-amyloid plaques in Alzheimer’s disease mice. Neuron 76:908–920
-
(2012)
Neuron
, vol.76
, pp. 908-920
-
-
DeMattos, R.B.1
Lu, J.2
Tang, Y.3
Racke Margaret, M.4
DeLong, C.A.5
Tzaferis John, A.6
Hole Justin, T.7
Forster Beth, M.8
McDonnell Peter, C.9
Liu, F.10
-
55
-
-
40849115110
-
Modulation of synaptic plasticity and Tau phosphorylation by wild-type and mutant presenilin1
-
COI: 1:CAS:528:DC%2BD1cXktVKgurY%3D, PID: 17222948
-
Dewachter I, Ris L, Croes S, Borghgraef P, Devijver H, Voets T, Nilius B, Godaux E, Van Leuven F (2008) Modulation of synaptic plasticity and Tau phosphorylation by wild-type and mutant presenilin1. Neurobiol Aging 29:639–652. doi:10.1016/j.neurobiolaging.2006.11.019
-
(2008)
Neurobiol Aging
, vol.29
, pp. 639-652
-
-
Dewachter, I.1
Ris, L.2
Croes, S.3
Borghgraef, P.4
Devijver, H.5
Voets, T.6
Nilius, B.7
Godaux, E.8
Van Leuven, F.9
-
56
-
-
67649819365
-
GSK3beta, a centre-staged kinase in neuropsychiatric disorders, modulates long term memory by inhibitory phosphorylation at serine-9
-
COI: 1:CAS:528:DC%2BD1MXotFCgt78%3D, PID: 19379814
-
Dewachter I, Ris L, Jaworski T, Seymour CM, Kremer A, Borghgraef P, De Vijver H, Godaux E, Van Leuven F (2009) GSK3beta, a centre-staged kinase in neuropsychiatric disorders, modulates long term memory by inhibitory phosphorylation at serine-9. Neurobiol Dis 35:193–200. doi:10.1016/j.nbd.2009.04.003
-
(2009)
Neurobiol Dis
, vol.35
, pp. 193-200
-
-
Dewachter, I.1
Ris, L.2
Jaworski, T.3
Seymour, C.M.4
Kremer, A.5
Borghgraef, P.6
De Vijver, H.7
Godaux, E.8
Van Leuven, F.9
-
57
-
-
77950460036
-
Changes in dendritic complexity and spine morphology in transgenic mice expressing human wild-type tau
-
PID: 20213269
-
Dickstein DL, Brautigam H, Stockton SD Jr, Schmeidler J, Hof PR (2010) Changes in dendritic complexity and spine morphology in transgenic mice expressing human wild-type tau. Brain Struct Funct 214:161–179. doi:10.1007/s00429-010-0245-1
-
(2010)
Brain Struct Funct
, vol.214
, pp. 161-179
-
-
Dickstein, D.L.1
Brautigam, H.2
Stockton, S.D.3
Schmeidler, J.4
Hof, P.R.5
-
58
-
-
84880712325
-
A phase 3 trial of semagacestat for treatment of Alzheimer’s disease
-
COI: 1:CAS:528:DC%2BC3sXhtF2nur7L, PID: 23883379
-
Doody RS, Raman R, Farlow M, Iwatsubo T, Vellas B, Joffe S, Kieburtz K, He F, Sun X, Thomas RG et al (2013) A phase 3 trial of semagacestat for treatment of Alzheimer’s disease. N Engl J Med 369:341–350. doi:10.1056/NEJMoa1210951
-
(2013)
N Engl J Med
, vol.369
, pp. 341-350
-
-
Doody, R.S.1
Raman, R.2
Farlow, M.3
Iwatsubo, T.4
Vellas, B.5
Joffe, S.6
Kieburtz, K.7
He, F.8
Sun, X.9
Thomas, R.G.10
-
59
-
-
84925022304
-
Immunotherapy alleviates amyloid-associated synaptic pathology in an Alzheimer’s disease mouse model
-
PID: 25281869
-
Dorostkar MM, Burgold S, Filser S, Barghorn S, Schmidt B, Anumala UR, Hillen H, Klein C, Herms J (2014) Immunotherapy alleviates amyloid-associated synaptic pathology in an Alzheimer’s disease mouse model. Brain. doi:10.1093/brain/awu280
-
(2014)
Brain
-
-
Dorostkar, M.M.1
Burgold, S.2
Filser, S.3
Barghorn, S.4
Schmidt, B.5
Anumala, U.R.6
Hillen, H.7
Klein, C.8
Herms, J.9
-
60
-
-
84903541550
-
Neuron-to-neuron wild-type Tau protein transfer through a trans-synaptic mechanism: relevance to sporadic tauopathies
-
PID: 24479894
-
Dujardin S, Lecolle K, Caillierez R, Begard S, Zommer N, Lachaud C, Carrier S, Dufour N, Auregan G, Winderickx J et al (2014) Neuron-to-neuron wild-type Tau protein transfer through a trans-synaptic mechanism: relevance to sporadic tauopathies. Acta Neuropathol Commun 2:14. doi:10.1186/2051-5960-2-14
-
(2014)
Acta Neuropathol Commun
, vol.2
, pp. 14
-
-
Dujardin, S.1
Lecolle, K.2
Caillierez, R.3
Begard, S.4
Zommer, N.5
Lachaud, C.6
Carrier, S.7
Dufour, N.8
Auregan, G.9
Winderickx, J.10
-
61
-
-
84872142073
-
Neuron loss in the 5XFAD mouse model of Alzheimer’s disease correlates with intraneuronal Abeta42 accumulation and Caspase-3 activation
-
COI: 1:CAS:528:DC%2BC3sXis1aksb0%3D, PID: 23316765
-
Eimer W, Vassar R (2013) Neuron loss in the 5XFAD mouse model of Alzheimer’s disease correlates with intraneuronal Abeta42 accumulation and Caspase-3 activation. Mol Neurodegener 8:2
-
(2013)
Mol Neurodegener
, vol.8
, pp. 2
-
-
Eimer, W.1
Vassar, R.2
-
62
-
-
84893080766
-
Local pruning of dendrites and spines by caspase-3-dependent and proteasome-limited mechanisms
-
PID: 24478350
-
Ertürk A, Wang Y, Sheng M (2014) Local pruning of dendrites and spines by caspase-3-dependent and proteasome-limited mechanisms. J Neurosci 34:1672–1688. doi:10.1523/jneurosci.3121-13.2014
-
(2014)
J Neurosci
, vol.34
, pp. 1672-1688
-
-
Ertürk, A.1
Wang, Y.2
Sheng, M.3
-
63
-
-
84873328025
-
Amyloid-beta oligomerization in Alzheimer dementia versus high-pathology controls
-
COI: 1:CAS:528:DC%2BC3sXitVOgs70%3D, PID: 23225543
-
Esparza TJ, Zhao H, Cirrito JR, Cairns NJ, Bateman RJ, Holtzman DM, Brody DL (2013) Amyloid-beta oligomerization in Alzheimer dementia versus high-pathology controls. Ann Neurol 73:104–119. doi:10.1002/ana.23748
-
(2013)
Ann Neurol
, vol.73
, pp. 104-119
-
-
Esparza, T.J.1
Zhao, H.2
Cirrito, J.R.3
Cairns, N.J.4
Bateman, R.J.5
Holtzman, D.M.6
Brody, D.L.7
-
64
-
-
0026589752
-
Increased expression of brain-derived neurotrophic factor mRNA in rat hippocampus is associated with improved spatial memory and enriched environment
-
COI: 1:CAS:528:DyaK38XisV2gu7o%3D, PID: 1407655
-
Falkenberg T, Mohammed AK, Henriksson B, Persson H, Winblad B, Lindefors N (1992) Increased expression of brain-derived neurotrophic factor mRNA in rat hippocampus is associated with improved spatial memory and enriched environment. Neurosci Lett 138:153–156. doi:10.1016/0304-3940(92)90494-R
-
(1992)
Neurosci Lett
, vol.138
, pp. 153-156
-
-
Falkenberg, T.1
Mohammed, A.K.2
Henriksson, B.3
Persson, H.4
Winblad, B.5
Lindefors, N.6
-
65
-
-
56149092503
-
Cell death after spinal cord injury is exacerbated by rapid TNF alpha-induced trafficking of GluR2-lacking AMPARs to the plasma membrane
-
COI: 1:CAS:528:DC%2BD1cXhtlGlt7%2FM, PID: 18971481
-
Ferguson AR, Christensen RN, Gensel JC, Miller BA, Sun F, Beattie EC, Bresnahan JC, Beattie MS (2008) Cell death after spinal cord injury is exacerbated by rapid TNF alpha-induced trafficking of GluR2-lacking AMPARs to the plasma membrane. J Neurosci 28:11391–11400. doi:10.1523/jneurosci.3708-08.2008
-
(2008)
J Neurosci
, vol.28
, pp. 11391-11400
-
-
Ferguson, A.R.1
Christensen, R.N.2
Gensel, J.C.3
Miller, B.A.4
Sun, F.5
Beattie, E.C.6
Bresnahan, J.C.7
Beattie, M.S.8
-
66
-
-
0036082812
-
Dendritic spine pathology: cause or consequence of neurological disorders?
-
PID: 12086707
-
Fiala JC, Spacek J, Harris KM (2002) Dendritic spine pathology: cause or consequence of neurological disorders? Brain Res Rev 39:29–54. doi:10.1016/s0165-0173(02)00158-3
-
(2002)
Brain Res Rev
, vol.39
, pp. 29-54
-
-
Fiala, J.C.1
Spacek, J.2
Harris, K.M.3
-
67
-
-
3242766671
-
Absence of C1q leads to less neuropathology in transgenic mouse models of Alzheimer’s disease
-
COI: 1:CAS:528:DC%2BD2cXmt1agu7c%3D, PID: 15269255
-
Fonseca MI, Zhou J, Botto M, Tenner AJ (2004) Absence of C1q leads to less neuropathology in transgenic mouse models of Alzheimer’s disease. J Neurosci 24:6457–6465. doi:10.1523/jneurosci.0901-04.2004
-
(2004)
J Neurosci
, vol.24
, pp. 6457-6465
-
-
Fonseca, M.I.1
Zhou, J.2
Botto, M.3
Tenner, A.J.4
-
68
-
-
84901779689
-
Genetic modulation of soluble Aβ rescues cognitive and synaptic impairment in a mouse model of Alzheimer’s disease
-
COI: 1:CAS:528:DC%2BC2cXps12qsb8%3D, PID: 24899710
-
Fowler SW, Chiang ACA, Savjani RR, Larson ME, Sherman MA, Schuler DR, Cirrito JR, Lesné SE, Jankowsky JL (2014) Genetic modulation of soluble Aβ rescues cognitive and synaptic impairment in a mouse model of Alzheimer’s disease. J Neurosci 34:7871–7885. doi:10.1523/jneurosci.0572-14.2014
-
(2014)
J Neurosci
, vol.34
, pp. 7871-7885
-
-
Fowler, S.W.1
Chiang, A.C.A.2
Savjani, R.R.3
Larson, M.E.4
Sherman, M.A.5
Schuler, D.R.6
Cirrito, J.R.7
Lesné, S.E.8
Jankowsky, J.L.9
-
69
-
-
79953162661
-
Experience-dependent structural plasticity in the cortex
-
COI: 1:CAS:528:DC%2BC3MXktF2jsbk%3D, PID: 21397343
-
Fu M, Zuo Y (2011) Experience-dependent structural plasticity in the cortex. Trends Neurosci 34:177–187
-
(2011)
Trends Neurosci
, vol.34
, pp. 177-187
-
-
Fu, M.1
Zuo, Y.2
-
70
-
-
80053131543
-
Diminished perisomatic GABAergic terminals on cortical neurons adjacent to amyloid plaques
-
PID: 19949482
-
Garcia-Marin V, Blazquez-Llorca L, Rodriguez J-R, Boluda S, Muntane G, Ferrer I, DeFelipe J (2009) Diminished perisomatic GABAergic terminals on cortical neurons adjacent to amyloid plaques. Front Neuroanat. doi:10.3389/neuro.05.028.2009
-
(2009)
Front Neuroanat
-
-
Garcia-Marin, V.1
Blazquez-Llorca, L.2
Rodriguez, J.-R.3
Boluda, S.4
Muntane, G.5
Ferrer, I.6
DeFelipe, J.7
-
71
-
-
0032868750
-
Neuronal cytoskeletal changes are an early consequence of repetitive head injury
-
COI: 1:CAS:528:DyaK1MXktVKgu74%3D, PID: 10442557
-
Geddes JF, Vowles GH, Nicoll JA, Revesz T (1999) Neuronal cytoskeletal changes are an early consequence of repetitive head injury. Acta Neuropathol 98:171–178
-
(1999)
Acta Neuropathol
, vol.98
, pp. 171-178
-
-
Geddes, J.F.1
Vowles, G.H.2
Nicoll, J.A.3
Revesz, T.4
-
72
-
-
0038708285
-
Tangle and neuron numbers, but not amyloid load, predict cognitive status in Alzheimer’s disease
-
COI: 1:STN:280:DC%2BD3s3it1Sqtg%3D%3D, PID: 12743238
-
Giannakopoulos P, Herrmann FR, Bussiere T, Bouras C, Kovari E, Perl DP, Morrison JH, Gold G, Hof PR (2003) Tangle and neuron numbers, but not amyloid load, predict cognitive status in Alzheimer’s disease. Neurology 60:1495–1500
-
(2003)
Neurology
, vol.60
, pp. 1495-1500
-
-
Giannakopoulos, P.1
Herrmann, F.R.2
Bussiere, T.3
Bouras, C.4
Kovari, E.5
Perl, D.P.6
Morrison, J.H.7
Gold, G.8
Hof, P.R.9
-
73
-
-
57649148788
-
Structural classification of toxic amyloid oligomers
-
COI: 1:CAS:528:DC%2BD1cXht1ynt7rK, PID: 18723507
-
Glabe CG (2008) Structural classification of toxic amyloid oligomers. J Biol Chem 283:29639–29643. doi:10.1074/jbc.R800016200
-
(2008)
J Biol Chem
, vol.283
, pp. 29639-29643
-
-
Glabe, C.G.1
-
74
-
-
0033622324
-
Intraneuronal Abeta42 accumulation in human brain
-
COI: 1:CAS:528:DC%2BD3cXns1ymsQ%3D%3D, PID: 10623648
-
Gouras GK, Tsai J, Naslund J, Vincent B, Edgar M, Checler F, Greenfield JP, Haroutunian V, Buxbaum JD, Xu H et al (2000) Intraneuronal Abeta42 accumulation in human brain. Am J Pathol 156:15–20
-
(2000)
Am J Pathol
, vol.156
, pp. 15-20
-
-
Gouras, G.K.1
Tsai, J.2
Naslund, J.3
Vincent, B.4
Edgar, M.5
Checler, F.6
Greenfield, J.P.7
Haroutunian, V.8
Buxbaum, J.D.9
Xu, H.10
-
75
-
-
84896847488
-
The inside-out amyloid hypothesis and synapse pathology in Alzheimer’s disease
-
COI: 1:CAS:528:DC%2BC2cXivVCmt74%3D, PID: 24080821
-
Gouras GK, Willén K, Faideau M (2014) The inside-out amyloid hypothesis and synapse pathology in Alzheimer’s disease. Neurodegener Dis 13:142–146
-
(2014)
Neurodegener Dis
, vol.13
, pp. 142-146
-
-
Gouras, G.K.1
Willén, K.2
Faideau, M.3
-
76
-
-
0035050289
-
Altered brain functional connectivity and impaired short-term memory in Alzheimer’s disease
-
COI: 1:STN:280:DC%2BD3M3jslWnug%3D%3D, PID: 11287374
-
Grady CL, Furey ML, Pietrini P, Horwitz B, Rapoport SI (2001) Altered brain functional connectivity and impaired short-term memory in Alzheimer’s disease. Brain 124:739–756
-
(2001)
Brain
, vol.124
, pp. 739-756
-
-
Grady, C.L.1
Furey, M.L.2
Pietrini, P.3
Horwitz, B.4
Rapoport, S.I.5
-
77
-
-
33847662852
-
Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer’s amyloid beta-peptide
-
COI: 1:CAS:528:DC%2BD2sXotFKmtw%3D%3D, PID: 17245412
-
Haass C, Selkoe DJ (2007) Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer’s amyloid beta-peptide. Nat Rev Mol Cell Biol 8:101–112. doi:10.1038/nrm2101
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 101-112
-
-
Haass, C.1
Selkoe, D.J.2
-
78
-
-
0032403433
-
Regulation of F-actin stability in dendritic spines by glutamate receptors and calcineurin
-
COI: 1:CAS:528:DyaK1cXnslyqsr0%3D, PID: 9822742
-
Halpain S, Hipolito A, Saffer L (1998) Regulation of F-actin stability in dendritic spines by glutamate receptors and calcineurin. J Neurosci 18:9835–9844
-
(1998)
J Neurosci
, vol.18
, pp. 9835-9844
-
-
Halpain, S.1
Hipolito, A.2
Saffer, L.3
-
79
-
-
84903820117
-
Neuronal driven pre-plaque inflammation in a transgenic rat model of Alzheimer’s disease
-
PID: 24831823
-
Hanzel CE, Pichet-Binette A, Pimentel LSB, Iulita MF, Allard S, Ducatenzeiler A, Do Carmo S, Cuello AC (2014) Neuronal driven pre-plaque inflammation in a transgenic rat model of Alzheimer’s disease. Neurobiol Aging. doi:10.1016/j.neurobiolaging.2014.03.026
-
(2014)
Neurobiol Aging
-
-
Hanzel, C.E.1
Pichet-Binette, A.2
Pimentel, L.S.B.3
Iulita, M.F.4
Allard, S.5
Ducatenzeiler, A.6
Do Carmo, S.7
Cuello, A.C.8
-
80
-
-
0037135111
-
The amyloid hypothesis of Alzheimer’s disease: progress and problems on the road to therapeutics
-
COI: 1:CAS:528:DC%2BD38Xls1Cju7s%3D, PID: 12130773
-
Hardy J, Selkoe DJ (2002) The amyloid hypothesis of Alzheimer’s disease: progress and problems on the road to therapeutics. Science 297:353–356. doi:10.1126/science.1072994
-
(2002)
Science
, vol.297
, pp. 353-356
-
-
Hardy, J.1
Selkoe, D.J.2
-
81
-
-
84866681445
-
Human P301L-mutant tau expression in mouse entorhinal-hippocampal network causes Tau aggregation and presynaptic pathology but no cognitive deficits
-
COI: 1:CAS:528:DC%2BC38XhsVelsb3L, PID: 23029293
-
Harris JA, Koyama A, Maeda S, Ho K, Devidze N, Dubal DB, Yu G-Q, Masliah E, Mucke L (2012) Human P301L-mutant tau expression in mouse entorhinal-hippocampal network causes Tau aggregation and presynaptic pathology but no cognitive deficits. PLoS One 7:e45881. doi:10.1371/journal.pone.0045881
-
(2012)
PLoS One
, vol.7
, pp. 45881
-
-
Harris, J.A.1
Koyama, A.2
Maeda, S.3
Ho, K.4
Devidze, N.5
Dubal, D.B.6
Yu, G.-Q.7
Masliah, E.8
Mucke, L.9
-
82
-
-
0035313299
-
Dendritic spines lost during glutamate receptor activation reemerge at original sites of synaptic contact
-
COI: 1:CAS:528:DC%2BD3MXjslClsrc%3D, PID: 11264313
-
Hasbani MJ, Schlief ML, Fisher DA, Goldberg MP (2001) Dendritic spines lost during glutamate receptor activation reemerge at original sites of synaptic contact. J Neurosci 21:2393–2403
-
(2001)
J Neurosci
, vol.21
, pp. 2393-2403
-
-
Hasbani, M.J.1
Schlief, M.L.2
Fisher, D.A.3
Goldberg, M.P.4
-
83
-
-
33845935564
-
Solution state characterization of amyloid beta-derived diffusible ligands
-
COI: 1:CAS:528:DC%2BD28Xht1yiurzI, PID: 17176037
-
Hepler RW, Grimm KM, Nahas DD, Breese R, Dodson EC, Acton P, Keller PM, Yeager M, Wang H, Shughrue P et al (2006) Solution state characterization of amyloid beta-derived diffusible ligands. Biochemistry 45:15157–15167. doi:10.1021/bi061850f
-
(2006)
Biochemistry
, vol.45
, pp. 15157-15167
-
-
Hepler, R.W.1
Grimm, K.M.2
Nahas, D.D.3
Breese, R.4
Dodson, E.C.5
Acton, P.6
Keller, P.M.7
Yeager, M.8
Wang, H.9
Shughrue, P.10
-
84
-
-
85048241364
-
Impaired plasticity of cortical dendritic spines in P301S tau transgenic mice
-
PID: 24344647
-
Hoffmann N, Dorostkar M, Blumenstock S, Goedert M, Herms J (2013) Impaired plasticity of cortical dendritic spines in P301S tau transgenic mice. Acta Neuropathol Commun 1:82
-
(2013)
Acta Neuropathol Commun
, vol.1
, pp. 82
-
-
Hoffmann, N.1
Dorostkar, M.2
Blumenstock, S.3
Goedert, M.4
Herms, J.5
-
85
-
-
84874350158
-
Involvement of presenilin holoprotein upregulation in calcium dyshomeostasis of Alzheimer’s disease
-
COI: 1:CAS:528:DC%2BC3sXmvFKgtbk%3D, PID: 23379308
-
Honarnejad K, Jung CKE, Lammich S, Arzberger T, Kretzschmar H, Herms J (2013) Involvement of presenilin holoprotein upregulation in calcium dyshomeostasis of Alzheimer’s disease. J Cell Mol Med 17:293–302. doi:10.1111/jcmm.12008
-
(2013)
J Cell Mol Med
, vol.17
, pp. 293-302
-
-
Honarnejad, K.1
Jung, C.K.E.2
Lammich, S.3
Arzberger, T.4
Kretzschmar, H.5
Herms, J.6
-
86
-
-
78650251838
-
Tau mislocalization to dendritic spines mediates synaptic dysfunction independently of neurodegeneration
-
COI: 1:CAS:528:DC%2BC3cXhsFykt7vO, PID: 21172610
-
Hoover BR, Reed MN, Su J, Penrod RD, Kotilinek LA, Grant MK, Pitstick R, Carlson GA, Lanier LM, Yuan LL et al (2010) Tau mislocalization to dendritic spines mediates synaptic dysfunction independently of neurodegeneration. Neuron 68:1067–1081
-
(2010)
Neuron
, vol.68
, pp. 1067-1081
-
-
Hoover, B.R.1
Reed, M.N.2
Su, J.3
Penrod, R.D.4
Kotilinek, L.A.5
Grant, M.K.6
Pitstick, R.7
Carlson, G.A.8
Lanier, L.M.9
Yuan, L.L.10
-
87
-
-
0033797832
-
Dendritic spine structural anomalies in fragile-X mental retardation syndrome
-
COI: 1:STN:280:DC%2BD3M%2FgvV2lsw%3D%3D, PID: 11007554
-
Irwin SA, Galvez R, Greenough WT (2000) Dendritic spine structural anomalies in fragile-X mental retardation syndrome. Cereb Cortex 10:1038–1044
-
(2000)
Cereb Cortex
, vol.10
, pp. 1038-1044
-
-
Irwin, S.A.1
Galvez, R.2
Greenough, W.T.3
-
88
-
-
77955322042
-
Dendritic function of tau mediates amyloid-[beta] toxicity in Alzheimer’s disease mouse models
-
COI: 1:CAS:528:DC%2BC3cXpvFKrtr4%3D, PID: 20655099
-
Ittner LM, Ke YD, Delerue F, Bi M, Gladbach A, van Eersel J, Wölfing H, Chieng BC, Christie MJ, Napier IA et al (2010) Dendritic function of tau mediates amyloid-[beta] toxicity in Alzheimer’s disease mouse models. Cell 142:387–397. doi:10.1016/j.cell.2010.06.036
-
(2010)
Cell
, vol.142
, pp. 387-397
-
-
Ittner, L.M.1
Ke, Y.D.2
Delerue, F.3
Bi, M.4
Gladbach, A.5
van Eersel, J.6
Wölfing, H.7
Chieng, B.C.8
Christie, M.J.9
Napier, I.A.10
-
89
-
-
84915747184
-
Disruption of amyloid plaques integrity affects the soluble oligomers content from Alzheimer disease brains
-
PID: 25485545
-
Jimenez S, Navarro V, Moyano J, Sanchez-Mico M, Torres M, Davila JC, Vizuete M, Gutierrez A, Vitorica J (2014) Disruption of amyloid plaques integrity affects the soluble oligomers content from Alzheimer disease brains. PLoS One 9:e114041. doi:10.1371/journal.pone.0114041
-
(2014)
PLoS One
, vol.9
, pp. 114041
-
-
Jimenez, S.1
Navarro, V.2
Moyano, J.3
Sanchez-Mico, M.4
Torres, M.5
Davila, J.C.6
Vizuete, M.7
Gutierrez, A.8
Vitorica, J.9
-
90
-
-
0009884512
-
Changes in the dendritic organization of neurons in the cerebral cortex following deafferentation
-
COI: 1:STN:280:DyaF38%2FltlOlsg%3D%3D, PID: 14452355
-
Jones WH, Thomas DB (1962) Changes in the dendritic organization of neurons in the cerebral cortex following deafferentation. J Anat 96:375–381
-
(1962)
J Anat
, vol.96
, pp. 375-381
-
-
Jones, W.H.1
Thomas, D.B.2
-
91
-
-
84925799248
-
Fibrillar amyloid plaque formation precedes microglial activation
-
PID: 25799372
-
Jung CK, Keppler K, Steinbach S, Blazquez-Llorca L, Herms J (2015) Fibrillar amyloid plaque formation precedes microglial activation. PLoS One 10:e0119768. doi:10.1371/journal.pone.0119768
-
(2015)
PLoS One
, vol.10
, pp. 0119768
-
-
Jung, C.K.1
Keppler, K.2
Steinbach, S.3
Blazquez-Llorca, L.4
Herms, J.5
-
92
-
-
81255199255
-
Role of presenilin1 in structural plasticity of cortical dendritic spines in vivo
-
COI: 1:CAS:528:DC%2BC3MXhs1Gqtb%2FK, PID: 21951279
-
Jung CKE, Fuhrmann M, Honarnejad K, Van Leuven F, Herms J (2011) Role of presenilin1 in structural plasticity of cortical dendritic spines in vivo. J Neurochem 119:1064–1073. doi:10.1111/j.1471-4159.2011.07503.x
-
(2011)
J Neurochem
, vol.119
, pp. 1064-1073
-
-
Jung, C.K.E.1
Fuhrmann, M.2
Honarnejad, K.3
Van Leuven, F.4
Herms, J.5
-
93
-
-
84896380943
-
Structural dynamics of dendritic spines are influenced by an environmental enrichment: an in vivo imaging study
-
PID: 23081882
-
Jung CKE, Herms J (2014) Structural dynamics of dendritic spines are influenced by an environmental enrichment: an in vivo imaging study. Cereb Cortex 24:377–384. doi:10.1093/cercor/bhs317
-
(2014)
Cereb Cortex
, vol.24
, pp. 377-384
-
-
Jung, C.K.E.1
Herms, J.2
-
94
-
-
0344672942
-
APP processing and synaptic function
-
COI: 1:CAS:528:DC%2BD3sXivFWkurY%3D, PID: 12670422
-
Kamenetz F, Tomita T, Hsieh H, Seabrook G, Borchelt D, Iwatsubo T, Sisodia S, Malinow R (2003) APP processing and synaptic function. Neuron 37:925–937. doi:10.1016/s0896-6273(03)00124-7
-
(2003)
Neuron
, vol.37
, pp. 925-937
-
-
Kamenetz, F.1
Tomita, T.2
Hsieh, H.3
Seabrook, G.4
Borchelt, D.5
Iwatsubo, T.6
Sisodia, S.7
Malinow, R.8
-
95
-
-
52949133401
-
Massive restructuring of neuronal circuits during functional reorganization of adult visual cortex
-
COI: 1:CAS:528:DC%2BD1cXhtFKhs7fK, PID: 18758460
-
Keck T, Mrsic-Flogel TD, Vaz Afonso M, Eysel UT, Bonhoeffer T, Hubener M (2008) Massive restructuring of neuronal circuits during functional reorganization of adult visual cortex. Nat Neurosci 11:1162–1167. doi:10.1038/nn.2181
-
(2008)
Nat Neurosci
, vol.11
, pp. 1162-1167
-
-
Keck, T.1
Mrsic-Flogel, T.D.2
Vaz Afonso, M.3
Eysel, U.T.4
Bonhoeffer, T.5
Hubener, M.6
-
96
-
-
79953765442
-
Decreased cerebral alpha4beta2* nicotinic acetylcholine receptor availability in patients with mild cognitive impairment and Alzheimer’s disease assessed with positron emission tomography
-
COI: 1:CAS:528:DC%2BC3MXhs1Gjs7w%3D, PID: 21069319
-
Kendziorra K, Wolf H, Meyer PM, Barthel H, Hesse S, Becker GA, Luthardt J, Schildan A, Patt M, Sorger D et al (2011) Decreased cerebral alpha4beta2* nicotinic acetylcholine receptor availability in patients with mild cognitive impairment and Alzheimer’s disease assessed with positron emission tomography. Eur J Nucl Med Mol Imaging 38:515–525. doi:10.1007/s00259-010-1644-5
-
(2011)
Eur J Nucl Med Mol Imaging
, vol.38
, pp. 515-525
-
-
Kendziorra, K.1
Wolf, H.2
Meyer, P.M.3
Barthel, H.4
Hesse, S.5
Becker, G.A.6
Luthardt, J.7
Schildan, A.8
Patt, M.9
Sorger, D.10
-
97
-
-
84880918212
-
Dendritic spine density, morphology, and fibrillar actin content surrounding amyloid-[beta] plaques in a mouse model of amyloid-[beta] deposition
-
PID: 23860033, (Publish Ahead of Print)
-
Kirkwood CM, Ciuchta J, Ikonomovic MD, Fish KN, Abrahamson EE, Murray PS, Klunk WE, Sweet RA (2013) Dendritic spine density, morphology, and fibrillar actin content surrounding amyloid-[beta] plaques in a mouse model of amyloid-[beta] deposition. J Neuropathol Exp Neurol. doi:10.1097/NEN.1090b1013e31829ecc31889(Publish Ahead of Print)
-
(2013)
J Neuropathol Exp Neurol
-
-
Kirkwood, C.M.1
Ciuchta, J.2
Ikonomovic, M.D.3
Fish, K.N.4
Abrahamson, E.E.5
Murray, P.S.6
Klunk, W.E.7
Sweet, R.A.8
-
98
-
-
84863192724
-
Apolipoprotein E4 effects in Alzheimer’s disease are mediated by synaptotoxic oligomeric amyloid-β
-
PID: 22637583
-
Koffie RM, Hashimoto T, Tai H-C, Kay KR, Serrano-Pozo A, Joyner D, Hou S, Kopeikina KJ, Frosch MP, Lee VM et al (2012) Apolipoprotein E4 effects in Alzheimer’s disease are mediated by synaptotoxic oligomeric amyloid-β. Brain 135:2155–2168. doi:10.1093/brain/aws127
-
(2012)
Brain
, vol.135
, pp. 2155-2168
-
-
Koffie, R.M.1
Hashimoto, T.2
Tai, H.-C.3
Kay, K.R.4
Serrano-Pozo, A.5
Joyner, D.6
Hou, S.7
Kopeikina, K.J.8
Frosch, M.P.9
Lee, V.M.10
-
99
-
-
62649174753
-
Oligomeric amyloid beta associates with postsynaptic densities and correlates with excitatory synapse loss near senile plaques
-
COI: 1:CAS:528:DC%2BD1MXjt1eis70%3D, PID: 19228947
-
Koffie RM, Meyer-Luehmann M, Hashimoto T, Adams KW, Mielke ML, Garcia-Alloza M, Micheva KD, Smith SJ, Kim ML, Lee VM et al (2009) Oligomeric amyloid beta associates with postsynaptic densities and correlates with excitatory synapse loss near senile plaques. Proc Natl Acad Sci 106:4012–4017. doi:10.1073/pnas.0811698106
-
(2009)
Proc Natl Acad Sci
, vol.106
, pp. 4012-4017
-
-
Koffie, R.M.1
Meyer-Luehmann, M.2
Hashimoto, T.3
Adams, K.W.4
Mielke, M.L.5
Garcia-Alloza, M.6
Micheva, K.D.7
Smith, S.J.8
Kim, M.L.9
Lee, V.M.10
-
100
-
-
47749113650
-
Aβ plaques lead to aberrant regulation of calcium homeostasis in vivo resulting in structural and functional disruption of neuronal networks
-
COI: 1:CAS:528:DC%2BD1cXpsFOgtrk%3D, PID: 18667150
-
Kuchibhotla KV, Goldman ST, Lattarulo CR, Wu H-Y, Hyman BT, Bacskai BJ (2008) Aβ plaques lead to aberrant regulation of calcium homeostasis in vivo resulting in structural and functional disruption of neuronal networks. Neuron 59:214–225. doi:10.1016/j.neuron.2008.06.008
-
(2008)
Neuron
, vol.59
, pp. 214-225
-
-
Kuchibhotla, K.V.1
Goldman, S.T.2
Lattarulo, C.R.3
Wu, H.-Y.4
Hyman, B.T.5
Bacskai, B.J.6
-
101
-
-
84891945085
-
Neurofibrillary tangle-bearing neurons are functionally integrated in cortical circuits in vivo
-
COI: 1:CAS:528:DC%2BC2cXps1CltQ%3D%3D, PID: 24368848
-
Kuchibhotla KV, Wegmann S, Kopeikina KJ, Hawkes J, Rudinskiy N, Andermann ML, Spires-Jones TL, Bacskai BJ, Hyman BT (2014) Neurofibrillary tangle-bearing neurons are functionally integrated in cortical circuits in vivo. Proc Natl Acad Sci 111:510–514. doi:10.1073/pnas.1318807111
-
(2014)
Proc Natl Acad Sci
, vol.111
, pp. 510-514
-
-
Kuchibhotla, K.V.1
Wegmann, S.2
Kopeikina, K.J.3
Hawkes, J.4
Rudinskiy, N.5
Andermann, M.L.6
Spires-Jones, T.L.7
Bacskai, B.J.8
Hyman, B.T.9
-
102
-
-
0034091707
-
Behavioral disturbances without amyloid deposits in mice overexpressing human amyloid precursor protein with Flemish (A692G) or Dutch (E693Q) mutation
-
COI: 1:CAS:528:DC%2BD3cXhtVegtb8%3D, PID: 10671319
-
Kumar-Singh S, Dewachter I, Moechars D, Lubke U, De Jonghe C, Ceuterick C, Checler F, Naidu A, Cordell B, Cras P et al (2000) Behavioral disturbances without amyloid deposits in mice overexpressing human amyloid precursor protein with Flemish (A692G) or Dutch (E693Q) mutation. Neurobiol Dis 7:9–22. doi:10.1006/nbdi.1999.0272
-
(2000)
Neurobiol Dis
, vol.7
, pp. 9-22
-
-
Kumar-Singh, S.1
Dewachter, I.2
Moechars, D.3
Lubke, U.4
De Jonghe, C.5
Ceuterick, C.6
Checler, F.7
Naidu, A.8
Cordell, B.9
Cras, P.10
-
103
-
-
84901399091
-
Truncated and modified amyloid-beta species
-
PID: 25031638
-
Kummer MP, Heneka MT (2014) Truncated and modified amyloid-beta species. Alzheimers Res Ther 6:28. doi:10.1186/alzrt258
-
(2014)
Alzheimers Res Ther
, vol.6
, pp. 28
-
-
Kummer, M.P.1
Heneka, M.T.2
-
104
-
-
0043095312
-
Dendritic spine loss in the hippocampus of young PDAPP and Tg2576 mice and its prevention by the ApoE2 genotype
-
COI: 1:CAS:528:DC%2BD3sXlvFOkt7g%3D, PID: 12901839
-
Lanz TA, Carter DB, Merchant KM (2003) Dendritic spine loss in the hippocampus of young PDAPP and Tg2576 mice and its prevention by the ApoE2 genotype. Neurobiol Dis 13:246–253
-
(2003)
Neurobiol Dis
, vol.13
, pp. 246-253
-
-
Lanz, T.A.1
Carter, D.B.2
Merchant, K.M.3
-
105
-
-
84655162704
-
Soluble Aβ oligomer production and toxicity
-
COI: 1:CAS:528:DC%2BC38XhsFyns7g%3D, PID: 22121920
-
Larson ME, Lesné SE (2012) Soluble Aβ oligomer production and toxicity. J Neurochem 120:125–139. doi:10.1111/j.1471-4159.2011.07478.x
-
(2012)
J Neurochem
, vol.120
, pp. 125-139
-
-
Larson, M.E.1
Lesné, S.E.2
-
106
-
-
33750365052
-
Are amyloid diseases caused by protein aggregates that mimic bacterial pore-forming toxins?
-
COI: 1:CAS:528:DC%2BD28XhtFKku7nM, PID: 16978447
-
Lashuel HA, Lansbury PT Jr (2006) Are amyloid diseases caused by protein aggregates that mimic bacterial pore-forming toxins? Q Rev Biophys 39:167–201. doi:10.1017/s0033583506004422
-
(2006)
Q Rev Biophys
, vol.39
, pp. 167-201
-
-
Lashuel, H.A.1
Lansbury, P.T.2
-
107
-
-
77957316313
-
CX3CR1 deficiency alters microglial activation and reduces beta-amyloid deposition in two Alzheimer’s disease mouse models
-
Lee S, Varvel NH, Konerth ME, Xu G, Cardona AE, Ransohoff RM, Lamb BT (2010) CX3CR1 deficiency alters microglial activation and reduces beta-amyloid deposition in two Alzheimer’s disease mouse models. Am J Pathol. doi:10.2353/ajpath.2010.100265
-
(2010)
Am J Pathol
-
-
Lee, S.1
Varvel, N.H.2
Konerth, M.E.3
Xu, G.4
Cardona, A.E.5
Ransohoff, R.M.6
Lamb, B.T.7
-
108
-
-
0034690063
-
Experience-dependent plasticity of dendritic spines in the developing rat barrel cortex in vivo
-
COI: 1:CAS:528:DC%2BD3cXjtVCrt7Y%3D, PID: 10786794
-
Lendvai B, Stern EA, Chen B, Svoboda K (2000) Experience-dependent plasticity of dendritic spines in the developing rat barrel cortex in vivo. Nature 404:876–881
-
(2000)
Nature
, vol.404
, pp. 876-881
-
-
Lendvai, B.1
Stern, E.A.2
Chen, B.3
Svoboda, K.4
-
109
-
-
39849101377
-
Rapid tumor necrosis factor alpha-induced exocytosis of glutamate receptor 2-lacking AMPA receptors to extrasynaptic plasma membrane potentiates excitotoxicity
-
COI: 1:CAS:528:DC%2BD1cXjt1Cqtbc%3D, PID: 18305246
-
Leonoudakis D, Zhao P, Beattie EC (2008) Rapid tumor necrosis factor alpha-induced exocytosis of glutamate receptor 2-lacking AMPA receptors to extrasynaptic plasma membrane potentiates excitotoxicity. J Neurosci 28:2119–2130. doi:10.1523/jneurosci.5159-07.2008
-
(2008)
J Neurosci
, vol.28
, pp. 2119-2130
-
-
Leonoudakis, D.1
Zhao, P.2
Beattie, E.C.3
-
110
-
-
84869159135
-
Lack of Tau proteins rescues neuronal cell death and decreases amyloidogenic processing of APP in APP/PS1 mice
-
COI: 1:CAS:528:DC%2BC38XhvFShsL7M, PID: 23026200
-
Leroy K, Ando K, Laporte V, Dedecker R, Suain V, Authelet M, Héraud C, Pierrot N, Yilmaz Z, Octave J-N et al (2012) Lack of Tau proteins rescues neuronal cell death and decreases amyloidogenic processing of APP in APP/PS1 mice. Am J Pathol 181:1928–1940. doi:10.1016/j.ajpath.2012.08.012
-
(2012)
Am J Pathol
, vol.181
, pp. 1928-1940
-
-
Leroy, K.1
Ando, K.2
Laporte, V.3
Dedecker, R.4
Suain, V.5
Authelet, M.6
Héraud, C.7
Pierrot, N.8
Yilmaz, Z.9
Octave, J.-N.10
-
111
-
-
84877293577
-
Brain amyloid-beta oligomers in ageing and Alzheimer’s disease
-
PID: 23576130
-
Lesné SE, Sherman MA, Grant M, Kuskowski M, Schneider JA, Bennett DA, Ashe KH (2013) Brain amyloid-beta oligomers in ageing and Alzheimer’s disease. Brain 136:1383–1398. doi:10.1093/brain/awt062
-
(2013)
Brain
, vol.136
, pp. 1383-1398
-
-
Lesné, S.E.1
Sherman, M.A.2
Grant, M.3
Kuskowski, M.4
Schneider, J.A.5
Bennett, D.A.6
Ashe, K.H.7
-
112
-
-
0025296269
-
Mutation of the Alzheimer’s disease amyloid gene in hereditary cerebral hemorrhage, Dutch type
-
COI: 1:CAS:528:DyaK3cXkslags7k%3D, PID: 2111584
-
Levy E, Carman MD, Fernandez-Madrid IJ, Power MD, Lieberburg I, van Duinen SG, Bots GT, Luyendijk W, Frangione B (1990) Mutation of the Alzheimer’s disease amyloid gene in hereditary cerebral hemorrhage, Dutch type. Science 248:1124–1126
-
(1990)
Science
, vol.248
, pp. 1124-1126
-
-
Levy, E.1
Carman, M.D.2
Fernandez-Madrid, I.J.3
Power, M.D.4
Lieberburg, I.5
van Duinen, S.G.6
Bots, G.T.7
Luyendijk, W.8
Frangione, B.9
-
113
-
-
84893529375
-
Profiling murine tau with 0N, 1N and 2N isoform-specific antibodies in brain and peripheral organs reveals distinct subcellular localization, with the 1N isoform being enriched in the nucleus
-
PID: 24386422
-
Liu C, Gotz J (2013) Profiling murine tau with 0N, 1N and 2N isoform-specific antibodies in brain and peripheral organs reveals distinct subcellular localization, with the 1N isoform being enriched in the nucleus. PLoS One 8:e84849. doi:10.1371/journal.pone.0084849
-
(2013)
PLoS One
, vol.8
, pp. 84849
-
-
Liu, C.1
Gotz, J.2
-
114
-
-
84856454190
-
Trans-synaptic spread of tau pathology in vivo
-
COI: 1:CAS:528:DC%2BC38XisFyksr4%3D, PID: 22312444
-
Liu L, Drouet V, Wu JW, Witter MP, Small SA, Clelland C, Duff K (2012) Trans-synaptic spread of tau pathology in vivo. PLoS One 7:e31302. doi:10.1371/journal.pone.0031302
-
(2012)
PLoS One
, vol.7
, pp. 31302
-
-
Liu, L.1
Drouet, V.2
Wu, J.W.3
Witter, M.P.4
Small, S.A.5
Clelland, C.6
Duff, K.7
-
115
-
-
78650338241
-
CX3CR1 in microglia regulates brain amyloid deposition through selective protofibrillar amyloid-{beta} phagocytosis
-
COI: 1:CAS:528:DC%2BC3cXhs1SlsbjI, PID: 21159979
-
Liu Z, Condello C, Schain A, Harb R, Grutzendler J (2010) CX3CR1 in microglia regulates brain amyloid deposition through selective protofibrillar amyloid-{beta} phagocytosis. J Neurosci 30:17091–17101. doi:10.1523/jneurosci.4403-10.2010
-
(2010)
J Neurosci
, vol.30
, pp. 17091-17101
-
-
Liu, Z.1
Condello, C.2
Schain, A.3
Harb, R.4
Grutzendler, J.5
-
116
-
-
42349104349
-
Plaque complement activation and cognitive loss in Alzheimer’s disease
-
PID: 18334032
-
Loeffler DA, Camp DM, Bennett DA (2008) Plaque complement activation and cognitive loss in Alzheimer’s disease. J Neuroinflammation 5:9. doi:10.1186/1742-2094-5-9
-
(2008)
J Neuroinflammation
, vol.5
, pp. 9
-
-
Loeffler, D.A.1
Camp, D.M.2
Bennett, D.A.3
-
117
-
-
0028929548
-
Neurofibrillary tangles in Niemann-Pick disease type C
-
PID: 7894998
-
Love S, Bridges LR, Case CP (1995) Neurofibrillary tangles in Niemann-Pick disease type C. Brain 118(Pt 1):119–129
-
(1995)
Brain
, vol.118
, pp. 119-129
-
-
Love, S.1
Bridges, L.R.2
Case, C.P.3
-
118
-
-
80053487755
-
Cerebral serotonin 4 receptors and amyloid-beta in early Alzheimer’s disease
-
COI: 1:CAS:528:DC%2BC3MXhtF2jtrvM, PID: 21673407
-
Madsen K, Neumann WJ, Holst K, Marner L, Haahr MT, Lehel S, Knudsen GM, Hasselbalch SG (2011) Cerebral serotonin 4 receptors and amyloid-beta in early Alzheimer’s disease. J Alzheimers Dis 26:457–466. doi:10.3233/jad-2011-110056
-
(2011)
J Alzheimers Dis
, vol.26
, pp. 457-466
-
-
Madsen, K.1
Neumann, W.J.2
Holst, K.3
Marner, L.4
Haahr, M.T.5
Lehel, S.6
Knudsen, G.M.7
Hasselbalch, S.G.8
-
119
-
-
79952810857
-
A[beta] oligomer at low nanomolar concentrations activates microglia and induces microglial neurotoxicity
-
PID: 20971854
-
Maezawa I, Zimin P, Wulff H, Jin L-W (2010) A[beta] oligomer at low nanomolar concentrations activates microglia and induces microglial neurotoxicity. J Biol Chem. doi:10.1074/jbc.M110.135244
-
(2010)
J Biol Chem
-
-
Maezawa, I.1
Zimin, P.2
Wulff, H.3
Jin, L.-W.4
-
120
-
-
44049089139
-
Amyloid-beta binds to the extracellular cysteine-rich domain of Frizzled and inhibits Wnt/beta-catenin signaling
-
COI: 1:CAS:528:DC%2BD1cXjslyqs7w%3D, PID: 18234671
-
Magdesian MH, Carvalho MM, Mendes FA, Saraiva LM, Juliano MA, Juliano L, Garcia-Abreu J, Ferreira ST (2008) Amyloid-beta binds to the extracellular cysteine-rich domain of Frizzled and inhibits Wnt/beta-catenin signaling. J Biol Chem 283:9359–9368. doi:10.1074/jbc.M707108200
-
(2008)
J Biol Chem
, vol.283
, pp. 9359-9368
-
-
Magdesian, M.H.1
Carvalho, M.M.2
Mendes, F.A.3
Saraiva, L.M.4
Juliano, M.A.5
Juliano, L.6
Garcia-Abreu, J.7
Ferreira, S.T.8
-
121
-
-
0036305484
-
AMPA receptor trafficking and synaptic plasticity
-
COI: 1:CAS:528:DC%2BD38XmtF2hsLw%3D, PID: 12052905
-
Malinow R, Malenka RC (2002) AMPA receptor trafficking and synaptic plasticity. Annu Rev Neurosci 25:103–126. doi:10.1146/annurev.neuro.25.112701.142758
-
(2002)
Annu Rev Neurosci
, vol.25
, pp. 103-126
-
-
Malinow, R.1
Malenka, R.C.2
-
122
-
-
0029813177
-
Comparison of neurodegenerative pathology in transgenic mice overexpressing V717F β-amyloid precursor protein and alzheimer’s disease
-
COI: 1:CAS:528:DyaK28XlsFOhsr4%3D, PID: 8795633
-
Masliah E, Sisk A, Mallory M, Mucke L, Schenk D, Games D (1996) Comparison of neurodegenerative pathology in transgenic mice overexpressing V717F β-amyloid precursor protein and alzheimer’s disease. J Neurosci 16:5795–5811
-
(1996)
J Neurosci
, vol.16
, pp. 5795-5811
-
-
Masliah, E.1
Sisk, A.2
Mallory, M.3
Mucke, L.4
Schenk, D.5
Games, D.6
-
123
-
-
0024364877
-
Immunohistochemical quantification of the synapse-related protein synaptophysin in Alzheimer disease
-
COI: 1:STN:280:DyaL1MzmsFyntw%3D%3D, PID: 2505201
-
Masliah E, Terry RD, DeTeresa RM, Hansen LA (1989) Immunohistochemical quantification of the synapse-related protein synaptophysin in Alzheimer disease. Neurosci Lett 103:234–239. doi:10.1016/0304-3940(89)90582-X
-
(1989)
Neurosci Lett
, vol.103
, pp. 234-239
-
-
Masliah, E.1
Terry, R.D.2
DeTeresa, R.M.3
Hansen, L.A.4
-
124
-
-
84931010790
-
Some observations on transneuronal cell degeneration in the olfactory bulb of the rabbit
-
Matthews MR, Powell TPS (1962) Some observations on transneuronal cell degeneration in the olfactory bulb of the rabbit. J Anat 96(89–102):103
-
(1962)
J Anat
, vol.96
, Issue.89-102
, pp. 103
-
-
Matthews, M.R.1
Powell, T.P.S.2
-
125
-
-
0026667044
-
Immunohistochemical localization of beta-amyloid precursor protein sequences in Alzheimer and normal brain tissue by light and electron microscopy
-
COI: 1:CAS:528:DyaK38XitFahurg%3D, PID: 1640495
-
McGeer PL, Akiyama H, Kawamata T, Yamada T, Walker DG, Ishii T (1992) Immunohistochemical localization of beta-amyloid precursor protein sequences in Alzheimer and normal brain tissue by light and electron microscopy. J Neurosci Res 31:428–442. doi:10.1002/jnr.490310305
-
(1992)
J Neurosci Res
, vol.31
, pp. 428-442
-
-
McGeer, P.L.1
Akiyama, H.2
Kawamata, T.3
Yamada, T.4
Walker, D.G.5
Ishii, T.6
-
126
-
-
84924284937
-
Pathological Tau disrupts ongoing network activity
-
PID: 25704951
-
Menkes-Caspi N, Yamin Hagar G, Kellner V, Spires-Jones Tara L, Cohen D, Stern Edward A (2015) Pathological Tau disrupts ongoing network activity. Neuron. doi:10.1016/j.neuron.2015.01.025
-
(2015)
Neuron
-
-
Menkes-Caspi, N.1
Yamin Hagar, G.2
Kellner, V.3
Spires-Jones Tara, L.4
Cohen, D.5
Stern Edward, A.6
-
127
-
-
84878836282
-
The influence of phospho-tau on dendritic spines of cortical pyramidal neurons in patients with Alzheimer’s disease
-
PID: 23715095
-
Merino-Serrais P, Benavides-Piccione R, Blazquez-Llorca L, Kastanauskaite A, Rabano A, Avila J, DeFelipe J (2013) The influence of phospho-tau on dendritic spines of cortical pyramidal neurons in patients with Alzheimer’s disease. Brain 136:1913–1928. doi:10.1093/brain/awt088
-
(2013)
Brain
, vol.136
, pp. 1913-1928
-
-
Merino-Serrais, P.1
Benavides-Piccione, R.2
Blazquez-Llorca, L.3
Kastanauskaite, A.4
Rabano, A.5
Avila, J.6
DeFelipe, J.7
-
128
-
-
84898719221
-
Tau phosphorylation and tau mislocalization mediate soluble Abeta oligomer-induced AMPA glutamate receptor signaling deficits
-
PID: 24713000
-
Miller EC, Teravskis PJ, Dummer BW, Zhao X, Huganir RL, Liao D (2014) Tau phosphorylation and tau mislocalization mediate soluble Abeta oligomer-induced AMPA glutamate receptor signaling deficits. Eur J Neurosci 39:1214–1224. doi:10.1111/ejn.12507
-
(2014)
Eur J Neurosci
, vol.39
, pp. 1214-1224
-
-
Miller, E.C.1
Teravskis, P.J.2
Dummer, B.W.3
Zhao, X.4
Huganir, R.L.5
Liao, D.6
-
129
-
-
80053104345
-
An immunohistochemical study of the serotonin 1A receptor in the hippocampus of subjects with Alzheimer’s disease
-
PID: 21269332
-
Mizukami K, Ishikawa M, Akatsu H, Abrahamson EE, Ikonomovic MD, Asada T (2011) An immunohistochemical study of the serotonin 1A receptor in the hippocampus of subjects with Alzheimer’s disease. Neuropathology 31:503–509. doi:10.1111/j.1440-1789.2010.01193.x
-
(2011)
Neuropathology
, vol.31
, pp. 503-509
-
-
Mizukami, K.1
Ishikawa, M.2
Akatsu, H.3
Abrahamson, E.E.4
Ikonomovic, M.D.5
Asada, T.6
-
130
-
-
84866361333
-
Interaction of endogenous Tau protein with synaptic proteins is regulated by N-Methyl-d-aspartate receptor-dependent Tau phosphorylation
-
PID: 22833681
-
Mondragón-Rodríguez S, Trillaud-Doppia E, Dudilot A, Bourgeois C, Lauzon M, Leclerc N, Boehm J (2012) Interaction of endogenous Tau protein with synaptic proteins is regulated by N-Methyl-d-aspartate receptor-dependent Tau phosphorylation. J Biol Chem 287:32040–32053. doi:10.1074/jbc.M112.401240
-
(2012)
J Biol Chem
, vol.287
, pp. 32040-32053
-
-
Mondragón-Rodríguez, S.1
Trillaud-Doppia, E.2
Dudilot, A.3
Bourgeois, C.4
Lauzon, M.5
Leclerc, N.6
Boehm, J.7
-
131
-
-
84859383216
-
Intracellular amyloid-β accumulation in calcium-binding protein-deficient neurons leads to amyloid-β plaque formation in animal model of Alzheimer’s disease
-
COI: 1:CAS:528:DC%2BC38XkvFWrsrY%3D, PID: 22269161
-
Moon M, Hong H-S, Nam DW, Baik SH, Song H, Kook S-Y, Kim YS, Lee J, Mook-Jung I (2012) Intracellular amyloid-β accumulation in calcium-binding protein-deficient neurons leads to amyloid-β plaque formation in animal model of Alzheimer’s disease. J Alzheimers Dis 29:615–628. doi:10.3233/JAD-2011-111778
-
(2012)
J Alzheimers Dis
, vol.29
, pp. 615-628
-
-
Moon, M.1
Hong, H.-S.2
Nam, D.W.3
Baik, S.H.4
Song, H.5
Kook, S.-Y.6
Kim, Y.S.7
Lee, J.8
Mook-Jung, I.9
-
132
-
-
84862495523
-
Involvement of perineuronal and perisynaptic extracellular matrix in Alzheimer’s disease neuropathology
-
COI: 1:CAS:528:DC%2BC38Xht1alsLvN
-
Morawski M, Bruckner G, Jager C, Seeger G, Matthews RT, Arendt T (2012) Involvement of perineuronal and perisynaptic extracellular matrix in Alzheimer’s disease neuropathology. Brain Pathol (Zurich, Switzerland) 22:547–561. doi:10.1111/j.1750-3639.2011.00557.x
-
(2012)
Brain Pathol (Zurich, Switzerland)
, vol.22
, pp. 547-561
-
-
Morawski, M.1
Bruckner, G.2
Jager, C.3
Seeger, G.4
Matthews, R.T.5
Arendt, T.6
-
133
-
-
0035997524
-
Intraneuronal Abeta42 accumulation in Down syndrome brain
-
COI: 1:CAS:528:DC%2BD38Xmt1Wlurs%3D, PID: 12440481
-
Mori C, Spooner ET, Wisniewsk KE, Wisniewski TM, Yamaguch H, Saido TC, Tolan DR, Selkoe DJ, Lemere CA (2002) Intraneuronal Abeta42 accumulation in Down syndrome brain. Amyloid 9:88–102
-
(2002)
Amyloid
, vol.9
, pp. 88-102
-
-
Mori, C.1
Spooner, E.T.2
Wisniewsk, K.E.3
Wisniewski, T.M.4
Yamaguch, H.5
Saido, T.C.6
Tolan, D.R.7
Selkoe, D.J.8
Lemere, C.A.9
-
134
-
-
80053102103
-
An immunohistochemical finding in glioneuronal lesions associated with epilepsy: the appearance of nestin-positive, CD34-positive and tau-accumulating cells
-
PID: 21276080
-
Nagaishi M, Arai M, Osawa T, Yokoo H, Hirato J, Yoshimoto Y, Nakazato Y (2011) An immunohistochemical finding in glioneuronal lesions associated with epilepsy: the appearance of nestin-positive, CD34-positive and tau-accumulating cells. Neuropathology 31:468–475. doi:10.1111/j.1440-1789.2010.01188.x
-
(2011)
Neuropathology
, vol.31
, pp. 468-475
-
-
Nagaishi, M.1
Arai, M.2
Osawa, T.3
Yokoo, H.4
Hirato, J.5
Yoshimoto, Y.6
Nakazato, Y.7
-
135
-
-
84931025734
-
The multifaceted nature of amyloid precursor protein and its proteolytic fragments: friends and foes
-
PID: 25287911
-
Nhan H, Chiang K, Koo E (2014) The multifaceted nature of amyloid precursor protein and its proteolytic fragments: friends and foes. Acta Neuropathol. doi:10.1007/s00401-014-1347-2
-
(2014)
Acta Neuropathol
-
-
Nhan, H.1
Chiang, K.2
Koo, E.3
-
136
-
-
0036194016
-
Structure and function of dendritic spines
-
COI: 1:CAS:528:DC%2BD38XisFGmsLg%3D, PID: 11826272
-
Nimchinsky EA, Sabatini BL, Svoboda K (2002) Structure and function of dendritic spines. Annu Rev Physiol 64:313–353. doi:10.1146/annurev.physiol.64.081501.160008
-
(2002)
Annu Rev Physiol
, vol.64
, pp. 313-353
-
-
Nimchinsky, E.A.1
Sabatini, B.L.2
Svoboda, K.3
-
137
-
-
84858117221
-
Amyloid-beta protein precursor regulates phosphorylation and cellular compartmentalization of microtubule associated protein tau
-
COI: 1:CAS:528:DC%2BC38XjtFyns7g%3D, PID: 22232001
-
Nizzari M, Barbieri F, Gentile MT, Passarella D, Caorsi C, Diaspro A, Taglialatela M, Pagano A, Colucci-D’Amato L, Florio T et al (2012) Amyloid-beta protein precursor regulates phosphorylation and cellular compartmentalization of microtubule associated protein tau. J Alzheimers Dis 29:211–227. doi:10.3233/jad-2011-101590
-
(2012)
J Alzheimers Dis
, vol.29
, pp. 211-227
-
-
Nizzari, M.1
Barbieri, F.2
Gentile, M.T.3
Passarella, D.4
Caorsi, C.5
Diaspro, A.6
Taglialatela, M.7
Pagano, A.8
Colucci-D’Amato, L.9
Florio, T.10
-
138
-
-
75949101857
-
Intraneuronal amyloid β accumulation and oxidative damage to nucleic acids in Alzheimer disease
-
COI: 1:CAS:528:DC%2BC3cXitV2ku7w%3D, PID: 20034567
-
Nunomura A, Tamaoki T, Tanaka K, Motohashi N, Nakamura M, Hayashi T, Yamaguchi H, Shimohama S, H-g Lee, Zhu X et al (2010) Intraneuronal amyloid β accumulation and oxidative damage to nucleic acids in Alzheimer disease. Neurobiol Dis 37:731–737. doi:10.1016/j.nbd.2009.12.012
-
(2010)
Neurobiol Dis
, vol.37
, pp. 731-737
-
-
Nunomura, A.1
Tamaoki, T.2
Tanaka, K.3
Motohashi, N.4
Nakamura, M.5
Hayashi, T.6
Yamaguchi, H.7
Shimohama, S.8
H-g, L.9
Zhu, X.10
-
139
-
-
33749521100
-
Intraneuronal β-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer’s disease mutations: potential factors in amyloid plaque formation
-
COI: 1:CAS:528:DC%2BD28XhtVymurbK, PID: 17021169
-
Oakley H, Cole SL, Logan S, Maus E, Shao P, Craft J, Guillozet-Bongaarts A, Ohno M, Disterhoft J, Van Eldik L et al (2006) Intraneuronal β-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer’s disease mutations: potential factors in amyloid plaque formation. J Neurosci 26:10129–10140. doi:10.1523/jneurosci.1202-06.2006
-
(2006)
J Neurosci
, vol.26
, pp. 10129-10140
-
-
Oakley, H.1
Cole, S.L.2
Logan, S.3
Maus, E.4
Shao, P.5
Craft, J.6
Guillozet-Bongaarts, A.7
Ohno, M.8
Disterhoft, J.9
Van Eldik, L.10
-
140
-
-
84926199558
-
Loss of neuronal GSK3[beta] reduces dendritic spine stability and attenuates excitatory synaptic transmission via [beta]-catenin
-
PID: 24912492
-
Ochs SM, Dorostkar MM, Aramuni G, Schon C, Filser S, Poschl J, Kremer A, Van Leuven F, Ovsepian SV, Herms J (2014) Loss of neuronal GSK3[beta] reduces dendritic spine stability and attenuates excitatory synaptic transmission via [beta]-catenin. Mol Psychiatry 20:482–489. doi:10.1038/mp.2014.55
-
(2014)
Mol Psychiatry
, vol.20
, pp. 482-489
-
-
Ochs, S.M.1
Dorostkar, M.M.2
Aramuni, G.3
Schon, C.4
Filser, S.5
Poschl, J.6
Kremer, A.7
Van Leuven, F.8
Ovsepian, S.V.9
Herms, J.10
-
141
-
-
84884840216
-
Alterations in alpha4beta2 nicotinic receptors in cognitive decline in Alzheimer’s aetiopathology
-
PID: 23975517
-
Okada H, Ouchi Y, Ogawa M, Futatsubashi M, Saito Y, Yoshikawa E, Terada T, Oboshi Y, Tsukada H, Ueki T et al (2013) Alterations in alpha4beta2 nicotinic receptors in cognitive decline in Alzheimer’s aetiopathology. Brain 136:3004–3017. doi:10.1093/brain/awt195
-
(2013)
Brain
, vol.136
, pp. 3004-3017
-
-
Okada, H.1
Ouchi, Y.2
Ogawa, M.3
Futatsubashi, M.4
Saito, Y.5
Yoshikawa, E.6
Terada, T.7
Oboshi, Y.8
Tsukada, H.9
Ueki, T.10
-
142
-
-
84906337254
-
Role of HIV in amyloid metabolism
-
PID: 24816714
-
Ortega M, Ances BM (2014) Role of HIV in amyloid metabolism. J Neuroimmune Pharmacol 9:483–491. doi:10.1007/s11481-014-9546-0
-
(2014)
J Neuroimmune Pharmacol
, vol.9
, pp. 483-491
-
-
Ortega, M.1
Ances, B.M.2
-
143
-
-
80052633284
-
Synaptic pruning by microglia is necessary for normal brain development
-
COI: 1:CAS:528:DC%2BC3MXhtFWqurbM, PID: 21778362
-
Paolicelli RC, Bolasco G, Pagani F, Maggi L, Scianni M, Panzanelli P, Giustetto M, Ferreira TA, Guiducci E, Dumas L et al (2011) Synaptic pruning by microglia is necessary for normal brain development. Science 333:1456–1458. doi:10.1126/science.1202529
-
(2011)
Science
, vol.333
, pp. 1456-1458
-
-
Paolicelli, R.C.1
Bolasco, G.2
Pagani, F.3
Maggi, L.4
Scianni, M.5
Panzanelli, P.6
Giustetto, M.7
Ferreira, T.A.8
Guiducci, E.9
Dumas, L.10
-
144
-
-
0032945724
-
Synaptic transmission and hippocampal long-term potentiation in transgenic mice expressing FAD-linked presenilin 1
-
COI: 1:CAS:528:DyaK1MXhslymt7o%3D, PID: 10078973
-
Parent A, Linden DJ, Sisodia SS, Borchelt DR (1999) Synaptic transmission and hippocampal long-term potentiation in transgenic mice expressing FAD-linked presenilin 1. Neurobiol Dis 6:56–62. doi:10.1006/nbdi.1998.0207
-
(1999)
Neurobiol Dis
, vol.6
, pp. 56-62
-
-
Parent, A.1
Linden, D.J.2
Sisodia, S.S.3
Borchelt, D.R.4
-
145
-
-
84894574217
-
Microglia promote learning-dependent synapse formation through brain-derived neurotrophic factor
-
COI: 1:STN:280:DC%2BC2c3psVKjtg%3D%3D, PID: 24360280
-
Parkhurst Christopher N, Yang G, Ninan I, Savas Jeffrey N, Yates Iii John R, Lafaille Juan J, Hempstead Barbara L, Littman Dan R, Gan W-B (2013) Microglia promote learning-dependent synapse formation through brain-derived neurotrophic factor. Cell 155:1596–1609. doi:10.1016/j.cell.2013.11.030
-
(2013)
Cell
, vol.155
, pp. 1596-1609
-
-
Parkhurst Christopher, N.1
Yang, G.2
Ninan, I.3
Savas Jeffrey, N.4
Yates Iii John, R.5
Lafaille Juan, J.6
Hempstead Barbara, L.7
Littman Dan, R.8
Gan, W.-B.9
-
146
-
-
33847113902
-
LTP Inhibits LTD in the Hippocampus via Regulation of GSK3[beta]
-
COI: 1:CAS:528:DC%2BD2sXjsVymt7w%3D, PID: 17329210
-
Peineau S, Taghibiglou C, Bradley C, Wong TP, Liu L, Lu J, Lo E, Wu D, Saule E, Bouschet T et al (2007) LTP Inhibits LTD in the Hippocampus via Regulation of GSK3[beta]. Neuron 53:703–717. doi:10.1016/j.neuron.2007.01.029
-
(2007)
Neuron
, vol.53
, pp. 703-717
-
-
Peineau, S.1
Taghibiglou, C.2
Bradley, C.3
Wong, T.P.4
Liu, L.5
Lu, J.6
Lo, E.7
Wu, D.8
Saule, E.9
Bouschet, T.10
-
147
-
-
79951960867
-
Dendritic spine pathology in neuropsychiatric disorders
-
COI: 1:CAS:528:DC%2BC3MXitlertrg%3D, PID: 21346746
-
Penzes P, Cahill ME, Jones KA, VanLeeuwen J-E, Woolfrey KM (2011) Dendritic spine pathology in neuropsychiatric disorders. Nat Neurosci 14:285–293
-
(2011)
Nat Neurosci
, vol.14
, pp. 285-293
-
-
Penzes, P.1
Cahill, M.E.2
Jones, K.A.3
VanLeeuwen, J.-E.4
Woolfrey, K.M.5
-
148
-
-
84896719288
-
Soluble pathological tau in the entorhinal cortex leads to presynaptic deficits in an early Alzheimer’s disease model
-
COI: 1:CAS:528:DC%2BC3sXhvVOnsLfP, PID: 24271788
-
Polydoro M, Dzhala VI, Pooler AM, Nicholls SB, McKinney AP, Sanchez L, Pitstick R, Carlson GA, Staley KJ, Spires-Jones TL et al (2014) Soluble pathological tau in the entorhinal cortex leads to presynaptic deficits in an early Alzheimer’s disease model. Acta Neuropathol 127:257–270. doi:10.1007/s00401-013-1215-5
-
(2014)
Acta Neuropathol
, vol.127
, pp. 257-270
-
-
Polydoro, M.1
Dzhala, V.I.2
Pooler, A.M.3
Nicholls, S.B.4
McKinney, A.P.5
Sanchez, L.6
Pitstick, R.7
Carlson, G.A.8
Staley, K.J.9
Spires-Jones, T.L.10
-
149
-
-
84891591874
-
Caspase-2 is required for dendritic spine and behavioural alterations in J20 APP transgenic mice
-
PID: 23748737
-
Pozueta J, Lefort R, Ribe EM, Troy CM, Arancio O, Shelanski M (2013) Caspase-2 is required for dendritic spine and behavioural alterations in J20 APP transgenic mice. Nat Commun 4:1939. doi:10.1038/ncomms2927
-
(2013)
Nat Commun
, vol.4
, pp. 1939
-
-
Pozueta, J.1
Lefort, R.2
Ribe, E.M.3
Troy, C.M.4
Arancio, O.5
Shelanski, M.6
-
150
-
-
84884285081
-
Synaptic changes in Alzheimer’s disease and its models
-
COI: 1:CAS:528:DC%2BC3sXhsVOksrjN, PID: 22687952
-
Pozueta J, Lefort R, Shelanski ML (2013) Synaptic changes in Alzheimer’s disease and its models. Neuroscience 251:51–65. doi:10.1016/j.neuroscience.2012.05.050
-
(2013)
Neuroscience
, vol.251
, pp. 51-65
-
-
Pozueta, J.1
Lefort, R.2
Shelanski, M.L.3
-
151
-
-
84925884202
-
Altered synaptic structure in the hippocampus in a mouse model of Alzheimer’s disease with soluble amyloid-beta oligomers and no plaque pathology
-
PID: 25312309
-
Price KA, Varghese M, Sowa A, Yuk F, Brautigam H, Ehrlich ME, Dickstein DL (2014) Altered synaptic structure in the hippocampus in a mouse model of Alzheimer’s disease with soluble amyloid-beta oligomers and no plaque pathology. Mol Neurodegener 9:41. doi:10.1186/1750-1326-9-41
-
(2014)
Mol Neurodegener
, vol.9
, pp. 41
-
-
Price, K.A.1
Varghese, M.2
Sowa, A.3
Yuk, F.4
Brautigam, H.5
Ehrlich, M.E.6
Dickstein, D.L.7
-
152
-
-
33746233383
-
Synapse formation and function is modulated by the amyloid precursor protein
-
COI: 1:CAS:528:DC%2BD28XntFejsb8%3D, PID: 16822978
-
Priller C, Bauer T, Mitteregger G, Krebs B, Kretzschmar HA, Herms J (2006) Synapse formation and function is modulated by the amyloid precursor protein. J Neurosci 26:7212–7221. doi:10.1523/jneurosci.1450-06.2006
-
(2006)
J Neurosci
, vol.26
, pp. 7212-7221
-
-
Priller, C.1
Bauer, T.2
Mitteregger, G.3
Krebs, B.4
Kretzschmar, H.A.5
Herms, J.6
-
153
-
-
33847766631
-
Mutant presenilin 1 alters synaptic transmission in cultured hippocampal neurons
-
COI: 1:CAS:528:DC%2BD2sXit1Klsw%3D%3D, PID: 17088253
-
Priller C, Dewachter I, Vassallo N, Paluch S, Pace C, Kretzschmar HA, Van Leuven F, Herms J (2007) Mutant presenilin 1 alters synaptic transmission in cultured hippocampal neurons. J Biol Chem 282:1119–1127. doi:10.1074/jbc.M605066200
-
(2007)
J Biol Chem
, vol.282
, pp. 1119-1127
-
-
Priller, C.1
Dewachter, I.2
Vassallo, N.3
Paluch, S.4
Pace, C.5
Kretzschmar, H.A.6
Van Leuven, F.7
Herms, J.8
-
154
-
-
33748988258
-
A[beta]42-driven cerebral amyloidosis in transgenic mice reveals early and robust pathology
-
COI: 1:CAS:528:DC%2BD28XptVSlsLY%3D, PID: 16906128
-
Radde R, Bolmont T, Kaeser SA, Coomaraswamy J, Lindau D, Stoltze L, Calhoun ME, Jaggi F, Wolburg H, Gengler S et al (2006) A[beta]42-driven cerebral amyloidosis in transgenic mice reveals early and robust pathology. EMBO Rep 7:940–946
-
(2006)
EMBO Rep
, vol.7
, pp. 940-946
-
-
Radde, R.1
Bolmont, T.2
Kaeser, S.A.3
Coomaraswamy, J.4
Lindau, D.5
Stoltze, L.6
Calhoun, M.E.7
Jaggi, F.8
Wolburg, H.9
Gengler, S.10
-
155
-
-
77953658771
-
Deleterious effects of amyloid beta oligomers acting as an extracellular scaffold for mGluR5
-
COI: 1:CAS:528:DC%2BC3cXnvFaksbk%3D, PID: 20547131
-
Renner M, Lacor PN, Velasco PT, Xu J, Contractor A, Klein WL, Triller A (2010) Deleterious effects of amyloid beta oligomers acting as an extracellular scaffold for mGluR5. Neuron 66:739–754. doi:10.1016/j.neuron.2010.04.029
-
(2010)
Neuron
, vol.66
, pp. 739-754
-
-
Renner, M.1
Lacor, P.N.2
Velasco, P.T.3
Xu, J.4
Contractor, A.5
Klein, W.L.6
Triller, A.7
-
156
-
-
79956110918
-
The cellular prion protein mediates neurotoxic signalling of β‐sheet‐rich conformers independent of prion replication
-
COI: 1:CAS:528:DC%2BC3MXjvVOiu7w%3D, PID: 21441896
-
Resenberger UK, Harmeier A, Woerner AC, Goodman JL, Müller V, Krishnan R, Vabulas RM, Kretzschmar HA, Lindquist S, Hartl FU et al (2011) The cellular prion protein mediates neurotoxic signalling of β‐sheet‐rich conformers independent of prion replication. EMBO J 30:2057–2070. doi:10.1038/emboj.2011.86
-
(2011)
EMBO J
, vol.30
, pp. 2057-2070
-
-
Resenberger, U.K.1
Harmeier, A.2
Woerner, A.C.3
Goodman, J.L.4
Müller, V.5
Krishnan, R.6
Vabulas, R.M.7
Kretzschmar, H.A.8
Lindquist, S.9
Hartl, F.U.10
-
157
-
-
10744230072
-
Ultrastructural and behavioural changes precede amyloid deposition in a transgenic model of Alzheimer’s disease
-
COI: 1:CAS:528:DC%2BD3sXosVyhur4%3D, PID: 14596862
-
Richardson JC, Kendal CE, Anderson R, Priest F, Gower E, Soden P, Gray R, Topps S, Howlett DR, Lavender D et al (2003) Ultrastructural and behavioural changes precede amyloid deposition in a transgenic model of Alzheimer’s disease. Neuroscience 122:213–228. doi:10.1016/S0306-4522(03)00389-0
-
(2003)
Neuroscience
, vol.122
, pp. 213-228
-
-
Richardson, J.C.1
Kendal, C.E.2
Anderson, R.3
Priest, F.4
Gower, E.5
Soden, P.6
Gray, R.7
Topps, S.8
Howlett, D.R.9
Lavender, D.10
-
158
-
-
84901337511
-
The type of Abeta-related neuronal degeneration differs between amyloid precursor protein (APP23) and amyloid beta-peptide (APP48) transgenic mice
-
PID: 24252227
-
Rijal Upadhaya A, Scheibe F, Kosterin I, Abramowski D, Gerth J, Kumar S, Liebau S, Yamaguchi H, Walter J, Staufenbiel M et al (2013) The type of Abeta-related neuronal degeneration differs between amyloid precursor protein (APP23) and amyloid beta-peptide (APP48) transgenic mice. Acta Neuropathol Commun 1:77. doi:10.1186/2051-5960-1-77
-
(2013)
Acta Neuropathol Commun
, vol.1
, pp. 77
-
-
Rijal Upadhaya, A.1
Scheibe, F.2
Kosterin, I.3
Abramowski, D.4
Gerth, J.5
Kumar, S.6
Liebau, S.7
Yamaguchi, H.8
Walter, J.9
Staufenbiel, M.10
-
159
-
-
78651506630
-
Amyloid-{beta}/Fyn-induced synaptic, network, and cognitive impairments depend on tau levels in multiple mouse models of Alzheimer’s disease
-
COI: 1:CAS:528:DC%2BC3MXht1arsrk%3D, PID: 21228179
-
Roberson ED, Halabisky B, Yoo JW, Yao J, Chin J, Yan F, Wu T, Hamto P, Devidze N, Yu G-Q et al (2011) Amyloid-{beta}/Fyn-induced synaptic, network, and cognitive impairments depend on tau levels in multiple mouse models of Alzheimer’s disease. J Neurosci 31:700–711. doi:10.1523/jneurosci.4152-10.2011
-
(2011)
J Neurosci
, vol.31
, pp. 700-711
-
-
Roberson, E.D.1
Halabisky, B.2
Yoo, J.W.3
Yao, J.4
Chin, J.5
Yan, F.6
Wu, T.7
Hamto, P.8
Devidze, N.9
Yu, G.-Q.10
-
160
-
-
34248181511
-
Reducing endogenous Tau ameliorates amyloid β-induced deficits in an Alzheimer’s disease mouse model
-
COI: 1:CAS:528:DC%2BD2sXkvVWrtrw%3D, PID: 17478722
-
Roberson ED, Scearce-Levie K, Palop JJ, Yan F, Cheng IH, Wu T, Gerstein H, Yu G-Q, Mucke L (2007) Reducing endogenous Tau ameliorates amyloid β-induced deficits in an Alzheimer’s disease mouse model. Science 316:750–754. doi:10.1126/science.1141736
-
(2007)
Science
, vol.316
, pp. 750-754
-
-
Roberson, E.D.1
Scearce-Levie, K.2
Palop, J.J.3
Yan, F.4
Cheng, I.H.5
Wu, T.6
Gerstein, H.7
Yu, G.-Q.8
Mucke, L.9
-
161
-
-
77952554382
-
Structural and functional changes in tau mutant mice neurons are not linked to the presence of NFTs
-
COI: 1:CAS:528:DC%2BC3cXlsFShsbs%3D, PID: 19665462
-
Rocher AB, Crimins JL, Amatrudo JM, Kinson MS, Todd-Brown MA, Lewis J, Luebke JI (2010) Structural and functional changes in tau mutant mice neurons are not linked to the presence of NFTs. Exp Neurol 223:385–393. doi:10.1016/j.expneurol.2009.07.029
-
(2010)
Exp Neurol
, vol.223
, pp. 385-393
-
-
Rocher, A.B.1
Crimins, J.L.2
Amatrudo, J.M.3
Kinson, M.S.4
Todd-Brown, M.A.5
Lewis, J.6
Luebke, J.I.7
-
162
-
-
84922392905
-
Asparagine endopeptidase cleaves tau and promotes neurodegeneration
-
COI: 1:CAS:528:DC%2BC2cXitVyku7rK, PID: 25375922
-
Rosenmann H (2014) Asparagine endopeptidase cleaves tau and promotes neurodegeneration. Nat Med 20:1236–1238. doi:10.1038/nm.3749
-
(2014)
Nat Med
, vol.20
, pp. 1236-1238
-
-
Rosenmann, H.1
-
163
-
-
84899647552
-
Single App knock-in mouse models of Alzheimer’s disease
-
COI: 1:CAS:528:DC%2BC2cXmtlWjsbs%3D, PID: 24728269
-
Saito T, Matsuba Y, Mihira N, Takano J, Nilsson P, Itohara S, Iwata N, Saido TC (2014) Single App knock-in mouse models of Alzheimer’s disease. Nat Neurosci 17:661–663. doi:10.1038/nn.3697
-
(2014)
Nat Neurosci
, vol.17
, pp. 661-663
-
-
Saito, T.1
Matsuba, Y.2
Mihira, N.3
Takano, J.4
Nilsson, P.5
Itohara, S.6
Iwata, N.7
Saido, T.C.8
-
164
-
-
1842731881
-
Src kinases: a hub for NMDA receptor regulation
-
COI: 1:CAS:528:DC%2BD2cXit12nu7k%3D, PID: 15034556
-
Salter MW, Kalia LV (2004) Src kinases: a hub for NMDA receptor regulation. Nat Rev Neurosci 5:317–328. doi:10.1038/nrn1368
-
(2004)
Nat Rev Neurosci
, vol.5
, pp. 317-328
-
-
Salter, M.W.1
Kalia, L.V.2
-
165
-
-
84867645474
-
Levetiracetam suppresses neuronal network dysfunction and reverses synaptic and cognitive deficits in an Alzheimer’s disease model
-
COI: 1:CAS:528:DC%2BC38Xhs1WmsbjK, PID: 22869752
-
Sanchez PE, Zhu L, Verret L, Vossel KA, Orr AG, Cirrito JR, Devidze N, Ho K, Yu G-Q, Palop JJ et al (2012) Levetiracetam suppresses neuronal network dysfunction and reverses synaptic and cognitive deficits in an Alzheimer’s disease model. Proc Natl Acad Sci 109:E2895–E2903. doi:10.1073/pnas.1121081109
-
(2012)
Proc Natl Acad Sci
, vol.109
, pp. 2895-2903
-
-
Sanchez, P.E.1
Zhu, L.2
Verret, L.3
Vossel, K.A.4
Orr, A.G.5
Cirrito, J.R.6
Devidze, N.7
Ho, K.8
Yu, G.-Q.9
Palop, J.J.10
-
166
-
-
84902486430
-
Distinct tau prion strains propagate in cells and mice and define different tauopathies
-
COI: 1:CAS:528:DC%2BC2cXoslClsrY%3D, PID: 24857020
-
Sanders DW, Kaufman SK, DeVos SL, Sharma AM, Mirbaha H, Li A, Barker SJ, Foley AC, Thorpe JR, Serpell LC et al (2014) Distinct tau prion strains propagate in cells and mice and define different tauopathies. Neuron 82:1271–1288. doi:10.1016/j.neuron.2014.04.047
-
(2014)
Neuron
, vol.82
, pp. 1271-1288
-
-
Sanders, D.W.1
Kaufman, S.K.2
DeVos, S.L.3
Sharma, A.M.4
Mirbaha, H.5
Li, A.6
Barker, S.J.7
Foley, A.C.8
Thorpe, J.R.9
Serpell, L.C.10
-
167
-
-
22344438508
-
Tau suppression in a neurodegenerative mouse model improves memory function
-
COI: 1:CAS:528:DC%2BD2MXmtVersLc%3D, PID: 16020737
-
SantaCruz K, Lewis J, Spires T, Paulson J, Kotilinek L, Ingelsson M, Guimaraes A, DeTure M, Ramsden M, McGowan E et al (2005) Tau suppression in a neurodegenerative mouse model improves memory function. Science 309:476–481. doi:10.1126/science.1113694
-
(2005)
Science
, vol.309
, pp. 476-481
-
-
SantaCruz, K.1
Lewis, J.2
Spires, T.3
Paulson, J.4
Kotilinek, L.5
Ingelsson, M.6
Guimaraes, A.7
DeTure, M.8
Ramsden, M.9
McGowan, E.10
-
168
-
-
84914698620
-
Synaptic change in the posterior cingulate gyrus in the progression of Alzheimer’s disease
-
COI: 1:CAS:528:DC%2BC2cXitVWks7jK, PID: 25147118
-
Scheff SW, Price DA, Ansari MA, Roberts KN, Schmitt FA, Ikonomovic MD, Mufson EJ (2015) Synaptic change in the posterior cingulate gyrus in the progression of Alzheimer’s disease. J Alzheimers Dis 43:1073–1090. doi:10.3233/jad-141518
-
(2015)
J Alzheimers Dis
, vol.43
, pp. 1073-1090
-
-
Scheff, S.W.1
Price, D.A.2
Ansari, M.A.3
Roberts, K.N.4
Schmitt, F.A.5
Ikonomovic, M.D.6
Mufson, E.J.7
-
169
-
-
34247611481
-
Synaptic alterations in CA1 in mild Alzheimer disease and mild cognitive impairment
-
COI: 1:STN:280:DC%2BD2s3mtFersg%3D%3D, PID: 17470753
-
Scheff SW, Price DA, Schmitt FA, DeKosky ST, Mufson EJ (2007) Synaptic alterations in CA1 in mild Alzheimer disease and mild cognitive impairment. Neurology 68:1501–1508. doi:10.1212/01.wnl.0000260698.46517.8f
-
(2007)
Neurology
, vol.68
, pp. 1501-1508
-
-
Scheff, S.W.1
Price, D.A.2
Schmitt, F.A.3
DeKosky, S.T.4
Mufson, E.J.5
-
170
-
-
33747760358
-
Hippocampal synaptic loss in early Alzheimer’s disease and mild cognitive impairment
-
COI: 1:CAS:528:DC%2BD28XoslKrs7s%3D, PID: 16289476
-
Scheff SW, Price DA, Schmitt FA, Mufson EJ (2006) Hippocampal synaptic loss in early Alzheimer’s disease and mild cognitive impairment. Neurobiol Aging 27:1372–1384. doi:10.1016/j.neurobiolaging.2005.09.012
-
(2006)
Neurobiol Aging
, vol.27
, pp. 1372-1384
-
-
Scheff, S.W.1
Price, D.A.2
Schmitt, F.A.3
Mufson, E.J.4
-
171
-
-
79957872121
-
Synaptic loss in the inferior temporal gyrus in mild cognitive impairment and Alzheimer’s disease
-
PID: 21297265
-
Scheff SW, Price DA, Schmitt FA, Scheff MA, Mufson EJ (2011) Synaptic loss in the inferior temporal gyrus in mild cognitive impairment and Alzheimer’s disease. J Alzheimers Dis 24:547–557. doi:10.3233/jad-2011-101782
-
(2011)
J Alzheimers Dis
, vol.24
, pp. 547-557
-
-
Scheff, S.W.1
Price, D.A.2
Schmitt, F.A.3
Scheff, M.A.4
Mufson, E.J.5
-
172
-
-
33749617597
-
On the seeding and oligomerization of pGlu-amyloid peptides (in vitro)
-
COI: 1:CAS:528:DC%2BD28XpslWns70%3D, PID: 17029395
-
Schilling S, Lauber T, Schaupp M, Manhart S, Scheel E, Böhm G, Demuth H-U (2006) On the seeding and oligomerization of pGlu-amyloid peptides (in vitro). Biochemistry 45:12393–12399. doi:10.1021/bi0612667
-
(2006)
Biochemistry
, vol.45
, pp. 12393-12399
-
-
Schilling, S.1
Lauber, T.2
Schaupp, M.3
Manhart, S.4
Scheel, E.5
Böhm, G.6
Demuth, H.-U.7
-
173
-
-
0035853828
-
Mutant presenilins disturb neuronal calcium homeostasis in the brain of transgenic mice, decreasing the threshold for excitotoxicity and facilitating long-term potentiation
-
COI: 1:CAS:528:DC%2BD3MXjtFymurk%3D, PID: 11278803
-
Schneider I, Reverse D, Dewachter I, Ris L, Caluwaerts N, Kuiperi C, Gilis M, Geerts H, Kretzschmar H, Godaux E et al (2001) Mutant presenilins disturb neuronal calcium homeostasis in the brain of transgenic mice, decreasing the threshold for excitotoxicity and facilitating long-term potentiation. J Biol Chem 276:11539–11544. doi:10.1074/jbc.M010977200
-
(2001)
J Biol Chem
, vol.276
, pp. 11539-11544
-
-
Schneider, I.1
Reverse, D.2
Dewachter, I.3
Ris, L.4
Caluwaerts, N.5
Kuiperi, C.6
Gilis, M.7
Geerts, H.8
Kretzschmar, H.9
Godaux, E.10
-
174
-
-
34547837494
-
Pathological Tau tangles localize to focal cortical dysplasia in older patients
-
PID: 17441989
-
Sen A, Thom M, Martinian L, Harding B, Cross JH, Nikolic M, Sisodiya SM (2007) Pathological Tau tangles localize to focal cortical dysplasia in older patients. Epilepsia 48:1447–1454. doi:10.1111/j.1528-1167.2007.01107.x
-
(2007)
Epilepsia
, vol.48
, pp. 1447-1454
-
-
Sen, A.1
Thom, M.2
Martinian, L.3
Harding, B.4
Cross, J.H.5
Nikolic, M.6
Sisodiya, S.M.7
-
175
-
-
0031969241
-
Molecular genetics of familial Alzheimer disease
-
COI: 1:STN:280:DyaK1c7ps12qsA%3D%3D, PID: 9537642
-
Shastry BS (1998) Molecular genetics of familial Alzheimer disease. Am J Med Sci 315:266–272
-
(1998)
Am J Med Sci
, vol.315
, pp. 266-272
-
-
Shastry, B.S.1
-
176
-
-
0037174634
-
Postsynaptic signaling and plasticity mechanisms
-
COI: 1:CAS:528:DC%2BD38XotFSnur4%3D, PID: 12399578
-
Sheng M, Kim MJ (2002) Postsynaptic signaling and plasticity mechanisms. Science 298:776–780. doi:10.1126/science.1075333
-
(2002)
Science
, vol.298
, pp. 776-780
-
-
Sheng, M.1
Kim, M.J.2
-
177
-
-
0037454477
-
Early intraneuronal Aβ deposition in the hippocampus of APP transgenic mice
-
COI: 1:CAS:528:DC%2BD3sXmsVShtA%3D%3D, PID: 12544843
-
Shie F-S, LeBoeur RC, Jin L-W (2003) Early intraneuronal Aβ deposition in the hippocampus of APP transgenic mice. NeuroReport 14:123–129
-
(2003)
NeuroReport
, vol.14
, pp. 123-129
-
-
Shie, F.-S.1
LeBoeur, R.C.2
Jin, L.-W.3
-
178
-
-
84879978794
-
Actin filaments and microtubules in dendritic spines
-
COI: 1:CAS:528:DC%2BC3sXhtVaksrvF, PID: 23692384
-
Shirao T, González-Billault C (2013) Actin filaments and microtubules in dendritic spines. J Neurochem 126:155–164. doi:10.1111/jnc.12313
-
(2013)
J Neurochem
, vol.126
, pp. 155-164
-
-
Shirao, T.1
González-Billault, C.2
-
179
-
-
84919426180
-
Dendritic structural degeneration is functionally linked to cellular hyperexcitability in a mouse model of Alzheimer’s disease
-
Šišková Z, Justus D, Kaneko H, Friedrichs D, Henneberg N, Beutel T, Pitsch J, Schoch S, Becker A, von der Kammer H et al (2014) Dendritic structural degeneration is functionally linked to cellular hyperexcitability in a mouse model of Alzheimer’s disease. Neuron 84:10. doi:10.1016/j.neuron.2014.10.024
-
(2014)
Neuron
, vol.84
, pp. 10
-
-
Šišková, Z.1
Justus, D.2
Kaneko, H.3
Friedrichs, D.4
Henneberg, N.5
Beutel, T.6
Pitsch, J.7
Schoch, S.8
Becker, A.9
von der Kammer, H.10
-
180
-
-
24644460177
-
Enhanced caffeine-induced Ca2+ release in the 3xTg-AD mouse model of Alzheimer’s disease
-
COI: 1:CAS:528:DC%2BD2MXhtVaksbvF, PID: 16156741
-
Smith IF, Hitt B, Green KN, Oddo S, LaFerla FM (2005) Enhanced caffeine-induced Ca2+ release in the 3xTg-AD mouse model of Alzheimer’s disease. J Neurochem 94:1711–1718. doi:10.1111/j.1471-4159.2005.03332.x
-
(2005)
J Neurochem
, vol.94
, pp. 1711-1718
-
-
Smith, I.F.1
Hitt, B.2
Green, K.N.3
Oddo, S.4
LaFerla, F.M.5
-
181
-
-
0033756376
-
Overview on the structure, composition, function, development, and plasticity of hippocampal dendritic spines
-
COI: 1:STN:280:DC%2BD3M7hvFyntw%3D%3D, PID: 11075821
-
Sorra KE, Harris KM (2000) Overview on the structure, composition, function, development, and plasticity of hippocampal dendritic spines. Hippocampus 10:501–511. doi:10.1002/1098-1063(2000)10:5<501:aid-hipo1>3.0.co;2-t
-
(2000)
Hippocampus
, vol.10
, pp. 501-511
-
-
Sorra, K.E.1
Harris, K.M.2
-
182
-
-
77952496309
-
Functional alterations in memory networks in early Alzheimer’s disease
-
COI: 1:CAS:528:DC%2BC3cXislykt7w%3D
-
Sperling R, Dickerson B, Pihlajamaki M, Vannini P, LaViolette P, Vitolo O, Hedden T, Becker JA, Rentz D, Selkoe D et al (2010) Functional alterations in memory networks in early Alzheimer’s disease. NeuroMol Med 12:27–43. doi:10.1007/s12017-009-8109-7
-
(2010)
NeuroMol Med
, vol.12
, pp. 27-43
-
-
Sperling, R.1
Dickerson, B.2
Pihlajamaki, M.3
Vannini, P.4
LaViolette, P.5
Vitolo, O.6
Hedden, T.7
Becker, J.A.8
Rentz, D.9
Selkoe, D.10
-
183
-
-
67650875899
-
Amyloid deposition is associated with impaired default network function in older persons without dementia
-
COI: 1:CAS:528:DC%2BD1MXhsVCiurjM, PID: 19640477
-
Sperling RA, LaViolette PS, O’Keefe K, O’Brien J, Rentz DM, Pihlajamaki M, Marshall G, Hyman BT, Selkoe DJ, Hedden T et al (2009) Amyloid deposition is associated with impaired default network function in older persons without dementia. Neuron 63:178–188. doi:10.1016/j.neuron.2009.07.003
-
(2009)
Neuron
, vol.63
, pp. 178-188
-
-
Sperling, R.A.1
LaViolette, P.S.2
O’Keefe, K.3
O’Brien, J.4
Rentz, D.M.5
Pihlajamaki, M.6
Marshall, G.7
Hyman, B.T.8
Selkoe, D.J.9
Hedden, T.10
-
184
-
-
0011444914
-
Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology
-
COI: 1:CAS:528:DyaK2sXnvFamtLs%3D, PID: 9371838
-
Sturchler-Pierrat C, Abramowski D, Duke M, Wiederhold K-H, Mistl C, Rothacher S, Ledermann B, Bürki K, Frey P, Paganetti PA et al (1997) Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology. Proc Natl Acad Sci 94:13287–13292
-
(1997)
Proc Natl Acad Sci
, vol.94
, pp. 13287-13292
-
-
Sturchler-Pierrat, C.1
Abramowski, D.2
Duke, M.3
Wiederhold, K.-H.4
Mistl, C.5
Rothacher, S.6
Ledermann, B.7
Bürki, K.8
Frey, P.9
Paganetti, P.A.10
-
185
-
-
33646945317
-
Enhanced ryanodine receptor recruitment contributes to Ca2+ disruptions in young, adult, and aged Alzheimer’s disease mice
-
COI: 1:CAS:528:DC%2BD28Xlt1Cju7Y%3D, PID: 16687509
-
Stutzmann GE, Smith I, Caccamo A, Oddo S, Laferla FM, Parker I (2006) Enhanced ryanodine receptor recruitment contributes to Ca2+ disruptions in young, adult, and aged Alzheimer’s disease mice. J Neurosci 26:5180–5189. doi:10.1523/jneurosci.0739-06.2006
-
(2006)
J Neurosci
, vol.26
, pp. 5180-5189
-
-
Stutzmann, G.E.1
Smith, I.2
Caccamo, A.3
Oddo, S.4
Laferla, F.M.5
Parker, I.6
-
186
-
-
84897463426
-
Reduced synaptic STIM2 expression and impaired store-operated calcium entry cause destabilization of mature spines in mutant presenilin mice
-
COI: 1:CAS:528:DC%2BC2cXls1Grsbs%3D, PID: 24698269
-
Sun S, Zhang H, Liu J, Popugaeva E, Xu NJ, Feske S, White CL 3rd, Bezprozvanny I (2014) Reduced synaptic STIM2 expression and impaired store-operated calcium entry cause destabilization of mature spines in mutant presenilin mice. Neuron 82:79–93. doi:10.1016/j.neuron.2014.02.019
-
(2014)
Neuron
, vol.82
, pp. 79-93
-
-
Sun, S.1
Zhang, H.2
Liu, J.3
Popugaeva, E.4
Xu, N.J.5
Feske, S.6
White, C.L.7
Bezprozvanny, I.8
-
187
-
-
0028922151
-
Neurofibrillary tangles in Niemann-Pick disease type C
-
COI: 1:STN:280:DyaK2M3nsVemuw%3D%3D, PID: 7754743
-
Suzuki K, Parker CC, Pentchev PG, Katz D, Ghetti B, D’Agostino AN, Carstea ED (1995) Neurofibrillary tangles in Niemann-Pick disease type C. Acta Neuropathol 89:227–238
-
(1995)
Acta Neuropathol
, vol.89
, pp. 227-238
-
-
Suzuki, K.1
Parker, C.C.2
Pentchev, P.G.3
Katz, D.4
Ghetti, B.5
D’Agostino, A.N.6
Carstea, E.D.7
-
188
-
-
84866478442
-
The synaptic accumulation of hyperphosphorylated tau oligomers in Alzheimer disease is associated with dysfunction of the ubiquitin-proteasome system
-
COI: 1:CAS:528:DC%2BC38XhsF2nsbzJ, PID: 22867711
-
Tai H-C, Serrano-Pozo A, Hashimoto T, Frosch MP, Spires-Jones TL, Hyman BT (2012) The synaptic accumulation of hyperphosphorylated tau oligomers in Alzheimer disease is associated with dysfunction of the ubiquitin-proteasome system. Am J Pathol 181:1426–1435. doi:10.1016/j.ajpath.2012.06.033
-
(2012)
Am J Pathol
, vol.181
, pp. 1426-1435
-
-
Tai, H.-C.1
Serrano-Pozo, A.2
Hashimoto, T.3
Frosch, M.P.4
Spires-Jones, T.L.5
Hyman, B.T.6
-
189
-
-
84964696705
-
Frequent and symmetric deposition of misfolded tau oligomers within presynaptic and postsynaptic terminals in Alzheimer’s disease
-
PID: 25330988
-
Tai H-C, Wang B, Serrano-Pozo A, Frosch M, Spires-Jones T, Hyman B (2014) Frequent and symmetric deposition of misfolded tau oligomers within presynaptic and postsynaptic terminals in Alzheimer’s disease. Acta Neuropathol Commun 2:146
-
(2014)
Acta Neuropathol Commun
, vol.2
, pp. 146
-
-
Tai, H.-C.1
Wang, B.2
Serrano-Pozo, A.3
Frosch, M.4
Spires-Jones, T.5
Hyman, B.6
-
190
-
-
84872765430
-
Accumulation of intraneuronal β-amyloid 42 peptides is associated with early changes in microtubule-associated protein 2 in neurites and synapses
-
COI: 1:CAS:528:DC%2BC3sXitVymt7Y%3D, PID: 23372648
-
Takahashi RH, Capetillo-Zarate E, Lin MT, Milner TA, Gouras GK (2013) Accumulation of intraneuronal β-amyloid 42 peptides is associated with early changes in microtubule-associated protein 2 in neurites and synapses. PLoS One 8:e51965. doi:10.1371/journal.pone.0051965
-
(2013)
PLoS One
, vol.8
, pp. 51965
-
-
Takahashi, R.H.1
Capetillo-Zarate, E.2
Lin, M.T.3
Milner, T.A.4
Gouras, G.K.5
-
191
-
-
77952878634
-
Co-occurrence of Alzheimer’s disease [beta]-amyloid and tau pathologies at synapses
-
COI: 1:CAS:528:DC%2BC3cXmtFWit7k%3D, PID: 18771816
-
Takahashi RH, Capetillo-Zarate E, Lin MT, Milner TA, Gouras GK (2010) Co-occurrence of Alzheimer’s disease [beta]-amyloid and tau pathologies at synapses. Neurobiol Aging 31:1145–1152
-
(2010)
Neurobiol Aging
, vol.31
, pp. 1145-1152
-
-
Takahashi, R.H.1
Capetillo-Zarate, E.2
Lin, M.T.3
Milner, T.A.4
Gouras, G.K.5
-
192
-
-
0036827031
-
Intraneuronal Alzheimer abeta42 accumulates in multivesicular bodies and is associated with synaptic pathology
-
COI: 1:CAS:528:DC%2BD38XptV2gtbg%3D, PID: 12414533
-
Takahashi RH, Milner TA, Li F, Nam EE, Edgar MA, Yamaguchi H, Beal MF, Xu H, Greengard P, Gouras GK (2002) Intraneuronal Alzheimer abeta42 accumulates in multivesicular bodies and is associated with synaptic pathology. Am J Pathol 161:1869–1879
-
(2002)
Am J Pathol
, vol.161
, pp. 1869-1879
-
-
Takahashi, R.H.1
Milner, T.A.2
Li, F.3
Nam, E.E.4
Edgar, M.A.5
Yamaguchi, H.6
Beal, M.F.7
Xu, H.8
Greengard, P.9
Gouras, G.K.10
-
193
-
-
73949088883
-
RAGE-mediated signaling contributes to intraneuronal transport of amyloid-β and neuronal dysfunction
-
COI: 1:CAS:528:DC%2BD1MXhsFGjtLvO, PID: 19901339
-
Takuma K, Fang F, Zhang W, Yan S, Fukuzaki E, Du H, Sosunov A, McKhann G, Funatsu Y, Nakamichi N et al (2009) RAGE-mediated signaling contributes to intraneuronal transport of amyloid-β and neuronal dysfunction. Proc Natl Acad Sci 106:20021–20026. doi:10.1073/pnas.0905686106
-
(2009)
Proc Natl Acad Sci
, vol.106
, pp. 20021-20026
-
-
Takuma, K.1
Fang, F.2
Zhang, W.3
Yan, S.4
Fukuzaki, E.5
Du, H.6
Sosunov, A.7
McKhann, G.8
Funatsu, Y.9
Nakamichi, N.10
-
194
-
-
68549127183
-
Synaptic activity reduces intraneuronal Aβ, promotes APP transport to synapses, and protects against aβ-related synaptic alterations
-
COI: 1:CAS:528:DC%2BD1MXpvFOmtb0%3D, PID: 19657023
-
Tampellini D, Rahman N, Gallo EF, Huang Z, Dumont M, Capetillo-Zarate E, Ma T, Zheng R, Lu B, Nanus DM et al (2009) Synaptic activity reduces intraneuronal Aβ, promotes APP transport to synapses, and protects against aβ-related synaptic alterations. J Neurosci 29:9704–9713. doi:10.1523/jneurosci.2292-09.2009
-
(2009)
J Neurosci
, vol.29
, pp. 9704-9713
-
-
Tampellini, D.1
Rahman, N.2
Gallo, E.F.3
Huang, Z.4
Dumont, M.5
Capetillo-Zarate, E.6
Ma, T.7
Zheng, R.8
Lu, B.9
Nanus, D.M.10
-
195
-
-
0025987048
-
Physical basis of cognitive alterations in Alzheimer’s disease: synapse loss is the major correlate of cognitive impairment
-
COI: 1:STN:280:DyaK387mtFOntw%3D%3D, PID: 1789684
-
Terry RD, Masliah E, Salmon DP, Butters N, DeTeresa R, Hill R, Hansen LA, Katzman R (1991) Physical basis of cognitive alterations in Alzheimer’s disease: synapse loss is the major correlate of cognitive impairment. Ann Neurol 30:572–580. doi:10.1002/ana.410300410
-
(1991)
Ann Neurol
, vol.30
, pp. 572-580
-
-
Terry, R.D.1
Masliah, E.2
Salmon, D.P.3
Butters, N.4
DeTeresa, R.5
Hill, R.6
Hansen, L.A.7
Katzman, R.8
-
196
-
-
0037172826
-
Phases of A{beta}-deposition in the human brain and its relevance for the development of AD
-
PID: 12084879
-
Thal DR, Rub U, Orantes M, Braak H (2002) Phases of A{beta}-deposition in the human brain and its relevance for the development of AD. Neurology 58:1791–1800
-
(2002)
Neurology
, vol.58
, pp. 1791-1800
-
-
Thal, D.R.1
Rub, U.2
Orantes, M.3
Braak, H.4
-
197
-
-
84901695801
-
Synaptic control of local translation: the plot thickens with new characters
-
COI: 1:CAS:528:DC%2BC3sXhslCqu7bF, PID: 24212248
-
Thomas MG, Pascual ML, Maschi D, Luchelli L, Boccaccio GL (2014) Synaptic control of local translation: the plot thickens with new characters. Cell Mol Life Sci 71:2219–2239. doi:10.1007/s00018-013-1506-y
-
(2014)
Cell Mol Life Sci
, vol.71
, pp. 2219-2239
-
-
Thomas, M.G.1
Pascual, M.L.2
Maschi, D.3
Luchelli, L.4
Boccaccio, G.L.5
-
198
-
-
0036200984
-
Occurrence of T cells in the brain of Alzheimer’s disease and other neurological diseases
-
COI: 1:CAS:528:DC%2BD38XhslWjtbc%3D, PID: 11958825
-
Togo T, Akiyama H, Iseki E, Kondo H, Ikeda K, Kato M, Oda T, Tsuchiya K, Kosaka K (2002) Occurrence of T cells in the brain of Alzheimer’s disease and other neurological diseases. J Neuroimmunol 124:83–92
-
(2002)
J Neuroimmunol
, vol.124
, pp. 83-92
-
-
Togo, T.1
Akiyama, H.2
Iseki, E.3
Kondo, H.4
Ikeda, K.5
Kato, M.6
Oda, T.7
Tsuchiya, K.8
Kosaka, K.9
-
199
-
-
84862644065
-
RNA-binding proteins involved in RNA localization and their implications in neuronal diseases
-
PID: 22708593
-
Tolino M, Köhrmann M, Kiebler MA (2012) RNA-binding proteins involved in RNA localization and their implications in neuronal diseases. Eur J Neurosci 35:1818–1836. doi:10.1111/j.1460-9568.2012.08160.x
-
(2012)
Eur J Neurosci
, vol.35
, pp. 1818-1836
-
-
Tolino, M.1
Köhrmann, M.2
Kiebler, M.A.3
-
200
-
-
77950617631
-
A mouse model of amyloid beta oligomers: their contribution to synaptic alteration, abnormal tau phosphorylation, glial activation, and neuronal loss in vivo
-
COI: 1:CAS:528:DC%2BC3cXlvVKntr0%3D, PID: 20371804
-
Tomiyama T, Matsuyama S, Iso H, Umeda T, Takuma H, Ohnishi K, Ishibashi K, Teraoka R, Sakama N, Yamashita T et al (2010) A mouse model of amyloid beta oligomers: their contribution to synaptic alteration, abnormal tau phosphorylation, glial activation, and neuronal loss in vivo. J Neurosci 30:4845–4856. doi:10.1523/jneurosci.5825-09.2010
-
(2010)
J Neurosci
, vol.30
, pp. 4845-4856
-
-
Tomiyama, T.1
Matsuyama, S.2
Iso, H.3
Umeda, T.4
Takuma, H.5
Ohnishi, K.6
Ishibashi, K.7
Teraoka, R.8
Sakama, N.9
Yamashita, T.10
-
201
-
-
84870524516
-
Brain-derived neurotrophic factor-dependent synaptic plasticity is suppressed by interleukin-1β via p38 mitogen-activated protein kinase
-
COI: 1:CAS:528:DC%2BC38XhvVCmu77P, PID: 23223292
-
Tong L, Prieto GA, Kramár EA, Smith ED, Cribbs DH, Lynch G, Cotman CW (2012) Brain-derived neurotrophic factor-dependent synaptic plasticity is suppressed by interleukin-1β via p38 mitogen-activated protein kinase. J Neurosci 32:17714–17724. doi:10.1523/jneurosci.1253-12.2012
-
(2012)
J Neurosci
, vol.32
, pp. 17714-17724
-
-
Tong, L.1
Prieto, G.A.2
Kramár, E.A.3
Smith, E.D.4
Cribbs, D.H.5
Lynch, G.6
Cotman, C.W.7
-
202
-
-
78649976052
-
Microglial interactions with synapses are modulated by visual experience
-
PID: 21072242
-
Tremblay M-È, Lowery RL, Majewska AK (2010) Microglial interactions with synapses are modulated by visual experience. PLoS Biol 8:e1000527
-
(2010)
PLoS Biol
, vol.8
, pp. 1000527
-
-
Tremblay, M.-È.1
Lowery, R.L.2
Majewska, A.K.3
-
203
-
-
33748140720
-
Presenilins form ER Ca2+ leak channels, a function disrupted by familial Alzheimer’s disease-linked mutations
-
COI: 1:CAS:528:DC%2BD28XpvVKiuro%3D, PID: 16959576
-
Tu H, Nelson O, Bezprozvanny A, Wang Z, Lee SF, Hao YH, Serneels L, De Strooper B, Yu G, Bezprozvanny I (2006) Presenilins form ER Ca2+ leak channels, a function disrupted by familial Alzheimer’s disease-linked mutations. Cell 126:981–993. doi:10.1016/j.cell.2006.06.059
-
(2006)
Cell
, vol.126
, pp. 981-993
-
-
Tu, H.1
Nelson, O.2
Bezprozvanny, A.3
Wang, Z.4
Lee, S.F.5
Hao, Y.H.6
Serneels, L.7
De Strooper, B.8
Yu, G.9
Bezprozvanny, I.10
-
204
-
-
84884200967
-
Metabotropic glutamate receptor 5 is a coreceptor for Alzheimer abeta oligomer bound to cellular prion protein
-
COI: 1:CAS:528:DC%2BC3sXhsVWjt7nE, PID: 24012003
-
Um JW, Kaufman AC, Kostylev M, Heiss JK, Stagi M, Takahashi H, Kerrisk ME, Vortmeyer A, Wisniewski T, Koleske AJ et al (2013) Metabotropic glutamate receptor 5 is a coreceptor for Alzheimer abeta oligomer bound to cellular prion protein. Neuron 79:887–902. doi:10.1016/j.neuron.2013.06.036
-
(2013)
Neuron
, vol.79
, pp. 887-902
-
-
Um, J.W.1
Kaufman, A.C.2
Kostylev, M.3
Heiss, J.K.4
Stagi, M.5
Takahashi, H.6
Kerrisk, M.E.7
Vortmeyer, A.8
Wisniewski, T.9
Koleske, A.J.10
-
205
-
-
84866065959
-
Alzheimer amyloid-[beta] oligomer bound to postsynaptic prion protein activates Fyn to impair neurons
-
COI: 1:CAS:528:DC%2BC38XhtVKnurzI, PID: 22820466
-
Um JW, Nygaard HB, Heiss JK, Kostylev MA, Stagi M, Vortmeyer A, Wisniewski T, Gunther EC, Strittmatter SM (2012) Alzheimer amyloid-[beta] oligomer bound to postsynaptic prion protein activates Fyn to impair neurons. Nat Neurosci 15:1227–1235. doi:10.1038/nn.3178
-
(2012)
Nat Neurosci
, vol.15
, pp. 1227-1235
-
-
Um, J.W.1
Nygaard, H.B.2
Heiss, J.K.3
Kostylev, M.A.4
Stagi, M.5
Vortmeyer, A.6
Wisniewski, T.7
Gunther, E.C.8
Strittmatter, S.M.9
-
206
-
-
84899962287
-
Neurofibrillary tangle formation by introducing wild-type human tau into APP transgenic mice
-
COI: 1:CAS:528:DC%2BC2cXivF2ntb0%3D, PID: 24531886
-
Umeda T, Maekawa S, Kimura T, Takashima A, Tomiyama T, Mori H (2014) Neurofibrillary tangle formation by introducing wild-type human tau into APP transgenic mice. Acta Neuropathol 127:685–698. doi:10.1007/s00401-014-1259-1
-
(2014)
Acta Neuropathol
, vol.127
, pp. 685-698
-
-
Umeda, T.1
Maekawa, S.2
Kimura, T.3
Takashima, A.4
Tomiyama, T.5
Mori, H.6
-
207
-
-
84866687889
-
Hypercholesterolemia accelerates intraneuronal accumulation of Aβ oligomers resulting in memory impairment in Alzheimer’s disease model mice
-
COI: 1:CAS:528:DC%2BC38XitFyitLk%3D, PID: 22273754
-
Umeda T, Tomiyama T, Kitajima E, Idomoto T, Nomura S, Lambert MP, Klein WL, Mori H (2012) Hypercholesterolemia accelerates intraneuronal accumulation of Aβ oligomers resulting in memory impairment in Alzheimer’s disease model mice. Life Sci 91:1169–1176. doi:10.1016/j.lfs.2011.12.022
-
(2012)
Life Sci
, vol.91
, pp. 1169-1176
-
-
Umeda, T.1
Tomiyama, T.2
Kitajima, E.3
Idomoto, T.4
Nomura, S.5
Lambert, M.P.6
Klein, W.L.7
Mori, H.8
-
208
-
-
18944397794
-
Identification and characterization of a new Down syndrome model, Ts[Rb(12.1716)]2Cje, resulting from a spontaneous Robertsonian fusion between T(171)65Dn and mouse chromosome 12
-
COI: 1:CAS:528:DC%2BD2MXitFOjtb8%3D, PID: 15859352
-
Villar AJ, Belichenko PV, Gillespie AM, Kozy HM, Mobley WC, Epstein CJ (2005) Identification and characterization of a new Down syndrome model, Ts[Rb(12.1716)]2Cje, resulting from a spontaneous Robertsonian fusion between T(171)65Dn and mouse chromosome 12. Mamm Genome 16:79–90
-
(2005)
Mamm Genome
, vol.16
, pp. 79-90
-
-
Villar, A.J.1
Belichenko, P.V.2
Gillespie, A.M.3
Kozy, H.M.4
Mobley, W.C.5
Epstein, C.J.6
-
209
-
-
0035339688
-
In vitro studies of amyloid beta-protein fibril assembly and toxicity provide clues to the aetiology of Flemish variant (Ala692→Gly) Alzheimer’s disease
-
COI: 1:CAS:528:DC%2BD3MXjslCmsrk%3D, PID: 11311152
-
Walsh DM, Hartley DM, Condron MM, Selkoe DJ, Teplow DB (2001) In vitro studies of amyloid beta-protein fibril assembly and toxicity provide clues to the aetiology of Flemish variant (Ala692→Gly) Alzheimer’s disease. Biochem J 355:869–877
-
(2001)
Biochem J
, vol.355
, pp. 869-877
-
-
Walsh, D.M.1
Hartley, D.M.2
Condron, M.M.3
Selkoe, D.J.4
Teplow, D.B.5
-
210
-
-
77956631366
-
Binding of amyloid beta peptide to beta2 adrenergic receptor induces PKA-dependent AMPA receptor hyperactivity
-
COI: 1:CAS:528:DC%2BC3cXhtFGgt77E, PID: 20395454
-
Wang D, Govindaiah G, Liu R, De Arcangelis V, Cox CL, Xiang YK (2010) Binding of amyloid beta peptide to beta2 adrenergic receptor induces PKA-dependent AMPA receptor hyperactivity. FASEB J 24:3511–3521. doi:10.1096/fj.10-156661
-
(2010)
FASEB J
, vol.24
, pp. 3511-3521
-
-
Wang, D.1
Govindaiah, G.2
Liu, R.3
De Arcangelis, V.4
Cox, C.L.5
Xiang, Y.K.6
-
211
-
-
67349247652
-
Presenilin-1 mutation impairs cholinergic modulation of synaptic plasticity and suppresses NMDA currents in hippocampus slices
-
COI: 1:CAS:528:DC%2BD1MXmtlCgsb8%3D, PID: 18068871
-
Wang Y, Greig NH, Yu QS, Mattson MP (2009) Presenilin-1 mutation impairs cholinergic modulation of synaptic plasticity and suppresses NMDA currents in hippocampus slices. Neurobiol Aging 30:1061–1068. doi:10.1016/j.neurobiolaging.2007.10.009
-
(2009)
Neurobiol Aging
, vol.30
, pp. 1061-1068
-
-
Wang, Y.1
Greig, N.H.2
Yu, Q.S.3
Mattson, M.P.4
-
212
-
-
84880117155
-
Down’s syndrome, neuroinflammation, and Alzheimer neuropathogenesis
-
COI: 1:CAS:528:DC%2BC3sXhtlCkt7rP, PID: 23866266
-
Wilcock DM, Griffin WS (2013) Down’s syndrome, neuroinflammation, and Alzheimer neuropathogenesis. J Neuroinflammation 10:84. doi:10.1186/1742-2094-10-84
-
(2013)
J Neuroinflammation
, vol.10
, pp. 84
-
-
Wilcock, D.M.1
Griffin, W.S.2
-
213
-
-
84875640007
-
Neuroinflammation and neuronal loss precede aβ plaque deposition in the hAPP-J20 mouse model of Alzheimer’s disease
-
COI: 1:CAS:528:DC%2BC3sXmtVemurc%3D, PID: 23560052
-
Wright AL, Zinn R, Hohensinn B, Konen LM, Beynon SB, Tan RP, Clark IA, Abdipranoto A, Vissel B (2013) Neuroinflammation and neuronal loss precede aβ plaque deposition in the hAPP-J20 mouse model of Alzheimer’s disease. PLoS One 8:e59586. doi:10.1371/journal.pone.0059586
-
(2013)
PLoS One
, vol.8
, pp. 59586
-
-
Wright, A.L.1
Zinn, R.2
Hohensinn, B.3
Konen, L.M.4
Beynon, S.B.5
Tan, R.P.6
Clark, I.A.7
Abdipranoto, A.8
Vissel, B.9
-
214
-
-
77249158836
-
Amyloid beta induces the morphological neurodegenerative triad of spine loss, dendritic simplification, and neuritic dystrophies through calcineurin activation
-
COI: 1:CAS:528:DC%2BC3cXisVKlt70%3D, PID: 20164348
-
Wu H-Y, Hudry E, Hashimoto T, Kuchibhotla K, Rozkalne A, Fan Z, Spires-Jones T, Xie H, Arbel-Ornath M, Grosskreutz CL et al (2010) Amyloid beta induces the morphological neurodegenerative triad of spine loss, dendritic simplification, and neuritic dystrophies through calcineurin activation. J Neurosci 30:2636–2649. doi:10.1523/jneurosci.4456-09.2010
-
(2010)
J Neurosci
, vol.30
, pp. 2636-2649
-
-
Wu, H.-Y.1
Hudry, E.2
Hashimoto, T.3
Kuchibhotla, K.4
Rozkalne, A.5
Fan, Z.6
Spires-Jones, T.7
Xie, H.8
Arbel-Ornath, M.9
Grosskreutz, C.L.10
-
215
-
-
84924262484
-
Presenilin-1 knockin mice reveal loss-of-function mechanism for familial Alzheimer’s disease
-
COI: 1:CAS:528:DC%2BC2MXktFehtr0%3D, PID: 25741723
-
Xia D, Watanabe H, Wu B, Lee SH, Li Y, Tsvetkov E, Bolshakov VY, Shen J, Kelleher RJ 3rd (2015) Presenilin-1 knockin mice reveal loss-of-function mechanism for familial Alzheimer’s disease. Neuron 85:967–981. doi:10.1016/j.neuron.2015.02.010
-
(2015)
Neuron
, vol.85
, pp. 967-981
-
-
Xia, D.1
Watanabe, H.2
Wu, B.3
Lee, S.H.4
Li, Y.5
Tsvetkov, E.6
Bolshakov, V.Y.7
Shen, J.8
Kelleher, R.J.9
-
216
-
-
84886925692
-
Mitochondrial alterations near amyloid plaques in an Alzheimer’s disease mouse model
-
COI: 1:CAS:528:DC%2BC3sXhslSmsb7F, PID: 24155308
-
Xie H, Guan J, Borrelli LA, Xu J, Serrano-Pozo A, Bacskai BJ (2013) Mitochondrial alterations near amyloid plaques in an Alzheimer’s disease mouse model. J Neurosci 33:17042–17051. doi:10.1523/jneurosci.1836-13.2013
-
(2013)
J Neurosci
, vol.33
, pp. 17042-17051
-
-
Xie, H.1
Guan, J.2
Borrelli, L.A.3
Xu, J.4
Serrano-Pozo, A.5
Bacskai, B.J.6
-
217
-
-
72449175148
-
Rapid formation and selective stabilization of synapses for enduring motor memories
-
COI: 1:CAS:528:DC%2BD1MXhsVyls7fI, PID: 19946267
-
Xu T, Yu X, Perlik AJ, Tobin WF, Zweig JA, Tennant K, Jones T, Zuo Y (2009) Rapid formation and selective stabilization of synapses for enduring motor memories. Nature 462:915–919. doi:10.1038/nature08389
-
(2009)
Nature
, vol.462
, pp. 915-919
-
-
Xu, T.1
Yu, X.2
Perlik, A.J.3
Tobin, W.F.4
Zweig, J.A.5
Tennant, K.6
Jones, T.7
Zuo, Y.8
-
218
-
-
72449182586
-
Stably maintained dendritic spines are associated with lifelong memories
-
COI: 1:CAS:528:DC%2BD1MXhsVylsLvM, PID: 19946265
-
Yang G, Pan F, Gan W-B (2009) Stably maintained dendritic spines are associated with lifelong memories. Nature 462:920–924. doi:10.1038/nature08577
-
(2009)
Nature
, vol.462
, pp. 920-924
-
-
Yang, G.1
Pan, F.2
Gan, W.-B.3
-
219
-
-
33846538660
-
Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model
-
COI: 1:CAS:528:DC%2BD2sXitVektbk%3D, PID: 17270732
-
Yoshiyama Y, Higuchi M, Zhang B, Huang S-M, Iwata N, Saido Takaomi C, Maeda J, Suhara T, Trojanowski JQ, Lee VMY (2007) Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model. Neuron 53:337–351
-
(2007)
Neuron
, vol.53
, pp. 337-351
-
-
Yoshiyama, Y.1
Higuchi, M.2
Zhang, B.3
Huang, S.-M.4
Iwata, N.5
Saido Takaomi, C.6
Maeda, J.7
Suhara, T.8
Trojanowski, J.Q.9
Lee, V.M.Y.10
-
220
-
-
84880281161
-
Electrical compartmentalization in dendritic spines
-
COI: 1:CAS:528:DC%2BC3sXhtlCku73J, PID: 23724997
-
Yuste R (2013) Electrical compartmentalization in dendritic spines. Annu Rev Neurosci 36:429–449. doi:10.1146/annurev-neuro-062111-150455
-
(2013)
Annu Rev Neurosci
, vol.36
, pp. 429-449
-
-
Yuste, R.1
-
221
-
-
0034095106
-
Enhanced synaptic potentiation in transgenic mice expressing presenilin 1 familial Alzheimer’s disease mutation is normalized with a benzodiazepine
-
COI: 1:CAS:528:DC%2BD3cXhtVegtb4%3D, PID: 10671322
-
Zaman SH, Parent A, Laskey A, Lee MK, Borchelt DR, Sisodia SS, Malinow R (2000) Enhanced synaptic potentiation in transgenic mice expressing presenilin 1 familial Alzheimer’s disease mutation is normalized with a benzodiazepine. Neurobiol Dis 7:54–63. doi:10.1006/nbdi.1999.0271
-
(2000)
Neurobiol Dis
, vol.7
, pp. 54-63
-
-
Zaman, S.H.1
Parent, A.2
Laskey, A.3
Lee, M.K.4
Borchelt, D.R.5
Sisodia, S.S.6
Malinow, R.7
-
222
-
-
84887828122
-
Amyloid-[beta] oligomers induce synaptic damage via Tau-dependent microtubule severing by TTLL6 and spastin
-
PID: 24065130, (advance online publication)
-
Zempel H, Luedtke J, Kumar Y, Biernat J, Dawson H, Mandelkow E, Mandelkow E-M (2013) Amyloid-[beta] oligomers induce synaptic damage via Tau-dependent microtubule severing by TTLL6 and spastin. EMBO J. doi:10.1038/emboj.2013.207(advance online publication)
-
(2013)
EMBO J
-
-
Zempel, H.1
Luedtke, J.2
Kumar, Y.3
Biernat, J.4
Dawson, H.5
Mandelkow, E.6
Mandelkow, E.-M.7
-
223
-
-
84860214055
-
Linking amyloid-β and Tau: amyloid-β induced synaptic dysfunction via local wreckage of the neuronal cytoskeleton
-
COI: 1:CAS:528:DC%2BC38XlvVOmsLw%3D, PID: 22156588
-
Zempel H, Mandelkow EM (2012) Linking amyloid-β and Tau: amyloid-β induced synaptic dysfunction via local wreckage of the neuronal cytoskeleton. Neurodegener Dis 10:64–72
-
(2012)
Neurodegener Dis
, vol.10
, pp. 64-72
-
-
Zempel, H.1
Mandelkow, E.M.2
-
224
-
-
77954123379
-
Role of presenilins in neuronal calcium homeostasis
-
COI: 1:CAS:528:DC%2BC3cXos1Knur0%3D, PID: 20573903
-
Zhang H, Sun S, Herreman A, De Strooper B, Bezprozvanny I (2010) Role of presenilins in neuronal calcium homeostasis. J Neurosci 30:8566–8580. doi:10.1523/jneurosci.1554-10.2010
-
(2010)
J Neurosci
, vol.30
, pp. 8566-8580
-
-
Zhang, H.1
Sun, S.2
Herreman, A.3
De Strooper, B.4
Bezprozvanny, I.5
-
225
-
-
84910669129
-
Cleavage of tau by asparagine endopeptidase mediates the neurofibrillary pathology in Alzheimer’s disease
-
COI: 1:CAS:528:DC%2BC2cXhslOisrvN, PID: 25326800
-
Zhang Z, Song M, Liu X, Kang SS, Kwon I-S, Duong DM, Seyfried NT, Hu WT, Liu Z, Wang J-Z et al (2014) Cleavage of tau by asparagine endopeptidase mediates the neurofibrillary pathology in Alzheimer’s disease. Nat Med 20:1254–1262. doi:10.1038/nm.3700
-
(2014)
Nat Med
, vol.20
, pp. 1254-1262
-
-
Zhang, Z.1
Song, M.2
Liu, X.3
Kang, S.S.4
Kwon, I.-S.5
Duong, D.M.6
Seyfried, N.T.7
Hu, W.T.8
Liu, Z.9
Wang, J.-Z.10
-
226
-
-
84894096181
-
Human APOE genotype affects intraneuronal Aβ1–42 accumulation in a lentiviral gene transfer model
-
COI: 1:CAS:528:DC%2BC2cXitFWit7Y%3D, PID: 24154541
-
Zhao W, Dumanis SB, Tamboli IY, Rodriguez GA, Jo LaDu M, Moussa CEH, William Rebeck G (2014) Human APOE genotype affects intraneuronal Aβ1–42 accumulation in a lentiviral gene transfer model. Hum Mol Genet 23:1365–1375. doi:10.1093/hmg/ddt525
-
(2014)
Hum Mol Genet
, vol.23
, pp. 1365-1375
-
-
Zhao, W.1
Dumanis, S.B.2
Tamboli, I.Y.3
Rodriguez, G.A.4
Jo LaDu, M.5
Moussa, C.E.H.6
William Rebeck, G.7
-
227
-
-
84902544067
-
Hyperphosphorylated tau is implicated in acquired epilepsy and neuropsychiatric comorbidities
-
COI: 1:CAS:528:DC%2BC3sXhvFajsbzI, PID: 24323428
-
Zheng P, Shultz SR, Hovens CM, Velakoulis D, Jones NC, O’Brien TJ (2014) Hyperphosphorylated tau is implicated in acquired epilepsy and neuropsychiatric comorbidities. Mol Neurobiol 49:1532–1539. doi:10.1007/s12035-013-8601-9
-
(2014)
Mol Neurobiol
, vol.49
, pp. 1532-1539
-
-
Zheng, P.1
Shultz, S.R.2
Hovens, C.M.3
Velakoulis, D.4
Jones, N.C.5
O’Brien, T.J.6
-
228
-
-
84929703953
-
Intraneuronal APP and extracellular Abeta independently cause dendritic spine pathology in transgenic mouse models of Alzheimer’s disease
-
Zou C, Montagna E, Shi Y, Peters F, Blazquez-Llorca L, Shi S, Filser S, Dorostkar MM, Herms J (2015) Intraneuronal APP and extracellular Abeta independently cause dendritic spine pathology in transgenic mouse models of Alzheimer’s disease. Acta Neuropathol. doi:10.1007/s00401-015-1421-4
-
(2015)
Acta Neuropathol
-
-
Zou, C.1
Montagna, E.2
Shi, Y.3
Peters, F.4
Blazquez-Llorca, L.5
Shi, S.6
Filser, S.7
Dorostkar, M.M.8
Herms, J.9
|