Axonal degeneration in an alzheimer mouse model is PS1 gene dose dependent and linked to intraneuronal aβ accumulation

Frontiers in Aging Neuroscience

Volumn 6, Issue JUN, 2014, Pages

  Christensen, Ditte Z ^a,d   Huettenrauch, Melanie ^a   Mitkovski, Miso ^b   Pradier, Laurent ^c   Wirths, Oliver ^a  

^a UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

^b MAX PLANCK INSTITUTE OF EXPERIMENTAL MEDICINE   (Germany)

^c SANOFI   (France)

^d H LUNDBECK A S   (Denmark)

Author keywords

Alzheimer; Amyloid; Axonal degeneration; Axonal transport; Axonopathy; Intraneuronal Abeta; Presenilin; Transgenic mice

Indexed keywords

AMYLOID BETA PROTEIN;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DENDRITE; GENE DOSAGE; MOUSE; NERVE FIBER; NERVE FIBER DEGENERATION; NEURITE; NONHUMAN;

EID: 84904574292     PISSN: None     EISSN: 16634365     Source Type: Journal    
DOI: 10.3389/fnagi.2014.00139     Document Type: Article

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