Rapid tumor necrosis factor α-induced exocytosis of glutamate receptor 2-lacking AMPA receptors to extrasynaptic plasma membrane potentiates excitotoxicity

Journal of Neuroscience

Volumn 28, Issue 9, 2008, Pages 2119-2130

  Leonoudakis, Dmitri ^a   Zhao, Pingwei ^a   Beattie, Eric C ^a  

^a CALIFORNIA PACIFIC MEDICAL CENTER   (United States)

Author keywords

AMPAR; Calcium permeable; Excitotoxicity; Extrasynaptic; TNF ; Trafficking

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; AMPA RECEPTOR; GLUTAMATE RECEPTOR 2; PHOSPHATIDYLINOSITOL 3 KINASE; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CELL DEATH; CONTROLLED STUDY; EXCITOTOXICITY; EXOCYTOSIS; IN VITRO STUDY; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION;

ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID; ANIMALS; BIOTINYLATION; CALCIUM; CELL MEMBRANE; CELLS, CULTURED; DRUG INTERACTIONS; EMBRYO, MAMMALIAN; ENZYME INHIBITORS; EXCITATORY AMINO ACID AGONISTS; EXOCYTOSIS; HIPPOCAMPUS; IMMUNOPRECIPITATION; MICROSCOPY, CONFOCAL; NEURONS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, AMPA; SYNAPSES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 39849101377     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.5159-07.2008     Document Type: Article

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