메뉴 건너뛰기




Volumn 55, Issue 3, 1998, Pages 326-335

Clinicopathologic studies in cognitively healthy aging and Alzheimer disease: Relation of histologic markers to dementia severity, age, sex, and apolipoprotein E genotype

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN E;

EID: 14444285507     PISSN: 00039942     EISSN: None     Source Type: Journal    
DOI: 10.1001/archneur.55.3.326     Document Type: Article
Times cited : (620)

References (97)
  • 1
    • 0027468235 scopus 로고
    • Neuropathologic indexes of Alzheimer's disease in demented and nondemented people aged 80 years and older
    • Berg L, McKeel DW Jr, Miller JP, Baty J, Morris JC. Neuropathologic indexes of Alzheimer's disease in demented and nondemented people aged 80 years and older. Arch Neurol. 1993;50:349-358.
    • (1993) Arch Neurol , vol.50 , pp. 349-358
    • Berg, L.1    McKeel Jr., D.W.2    Miller, J.P.3    Baty, J.4    Morris, J.C.5
  • 2
    • 0021847557 scopus 로고
    • Some morphometric observations on the cerebral cortex and hippocampus in presenile Alzheimer's disease, senile dementia of the Alzheimer type and Down's syndrome in middle age
    • Mann DMA, Yates PO, Marcyniuk B. Some morphometric observations on the cerebral cortex and hippocampus in presenile Alzheimer's disease, senile dementia of the Alzheimer type and Down's syndrome in middle age. J Neurol Sci. 1985;69:139-159.
    • (1985) J Neurol Sci , vol.69 , pp. 139-159
    • Mann, D.M.A.1    Yates, P.O.2    Marcyniuk, B.3
  • 4
    • 0023472509 scopus 로고
    • Neuron numbers and dendritic extent in normal aging and Alzheimer's disease
    • Coleman PD, Flood DG. Neuron numbers and dendritic extent in normal aging and Alzheimer's disease. Neurobiol Aging. 1987;8:521-545.
    • (1987) Neurobiol Aging , vol.8 , pp. 521-545
    • Coleman, P.D.1    Flood, D.G.2
  • 5
    • 0023831289 scopus 로고
    • Neocortical morphometry, lesion counts, and choline acetyltransferase levels in the age spectrum of Alzheimer's disease
    • Hansen LA, DeTeresa R, Terry RD. Neocortical morphometry, lesion counts, and choline acetyltransferase levels in the age spectrum of Alzheimer's disease. Neurology. 1988;38:48-54.
    • (1988) Neurology , vol.38 , pp. 48-54
    • Hansen, L.A.1    DeTeresa, R.2    Terry, R.D.3
  • 6
    • 0023905906 scopus 로고
    • Clinical, pathological, and neurochemical changes in dementia: A subgroup with preserved mental status and numerous neocortical plaques
    • Katzman R, Terry RD, DeTeresa R, et al. Clinical, pathological, and neurochemical changes in dementia: a subgroup with preserved mental status and numerous neocortical plaques. Ann Neurol. 1988;23:53-59.
    • (1988) Ann Neurol , vol.23 , pp. 53-59
    • Katzman, R.1    Terry, R.D.2    DeTeresa, R.3
  • 7
    • 0023762975 scopus 로고
    • Clinicopathologic studies in dementia: Nondemented subjects with pathologically confirmed Alzheimer's disease
    • Crystal H, Dickson DW, Fuld P, et al. Clinicopathologic studies in dementia: nondemented subjects with pathologically confirmed Alzheimer's disease. Neurology. 1988;38:1682-1687.
    • (1988) Neurology , vol.38 , pp. 1682-1687
    • Crystal, H.1    Dickson, D.W.2    Fuld, P.3
  • 8
    • 0026512066 scopus 로고
    • Identification of normal and pathological aging in prospectively studied nondemented elderly humans
    • Dickson DW, Crystal HA, Mattiace LA, et al. Identification of normal and pathological aging in prospectively studied nondemented elderly humans. Neurobiol Aging. 1992;13:179-189.
    • (1992) Neurobiol Aging , vol.13 , pp. 179-189
    • Dickson, D.W.1    Crystal, H.A.2    Mattiace, L.A.3
  • 9
    • 0025780497 scopus 로고
    • Very mild Alzheimer's disease: Informant-based clinical, psychometric, and pathological distinction from normal aging
    • Morris JC, McKeel DW Jr, Storandt M, et al. Very mild Alzheimer's disease: informant-based clinical, psychometric, and pathological distinction from normal aging. Neurology. 1991;41:469-478.
    • (1991) Neurology , vol.41 , pp. 469-478
    • Morris, J.C.1    McKeel Jr., D.W.2    Storandt, M.3
  • 10
    • 0029892175 scopus 로고    scopus 로고
    • Cerebral amyloid deposition and diffuse plaques in "normal" aging: Evidence for presymptomatic and very mild Alzheimer's disease
    • Morris JC, Storandt M, McKeel DW Jr, et al. Cerebral amyloid deposition and diffuse plaques in "normal" aging: evidence for presymptomatic and very mild Alzheimer's disease. Neurology. 1996;46:707-719.
    • (1996) Neurology , vol.46 , pp. 707-719
    • Morris, J.C.1    Storandt, M.2    McKeel Jr., D.W.3
  • 11
    • 0027327267 scopus 로고
    • Association of apolipoprotein E allele ε4 with late-onset familial and sporadic Alzheimer's disease
    • Saunders AM, Strittmatter WJ, Schmechel D, et al. Association of apolipoprotein E allele ε4 with late-onset familial and sporadic Alzheimer's disease. Neurology. 1993;43:1467-1472.
    • (1993) Neurology , vol.43 , pp. 1467-1472
    • Saunders, A.M.1    Strittmatter, W.J.2    Schmechel, D.3
  • 12
    • 0027407565 scopus 로고
    • Apolipoprotein E: High avidity binding to b-amyloid and increased frequency of type 4 allele in late onset familial Alzheimer disease
    • Strittmatter WJ, Saunders AM, Schmechel D, et al. Apolipoprotein E: high avidity binding to b-amyloid and increased frequency of type 4 allele in late onset familial Alzheimer disease. Proc Natl Acad Sci U S A. 1993;90:1977-1981.
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 1977-1981
    • Strittmatter, W.J.1    Saunders, A.M.2    Schmechel, D.3
  • 13
    • 0027365822 scopus 로고
    • Increased amyloid β-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease
    • Schmechel DE, Saunders AM, Strittmatter WJ, et al. Increased amyloid β-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease. Proc Natl Acad Sci U S A. 1993;90:9649-9653.
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 9649-9653
    • Schmechel, D.E.1    Saunders, A.M.2    Strittmatter, W.J.3
  • 14
    • 0027374047 scopus 로고
    • Apolipoprotein E in sporadic Alzheimer's disease: Allelic variation and receptor interactions
    • Rebeck GW, Reiter JS, Strickland DK, Hyman BT. Apolipoprotein E in sporadic Alzheimer's disease: allelic variation and receptor interactions. Neuron. 1993;11:575-580.
    • (1993) Neuron , vol.11 , pp. 575-580
    • Rebeck, G.W.1    Reiter, J.S.2    Strickland, D.K.3    Hyman, B.T.4
  • 15
    • 0030005627 scopus 로고    scopus 로고
    • Apolipoprotein E alleles as risk factors in Alzheimer's disease
    • Roses AD. Apolipoprotein E alleles as risk factors in Alzheimer's disease. Annu Rev Med. 1996;47:387-400.
    • (1996) Annu Rev Med , vol.47 , pp. 387-400
    • Roses, A.D.1
  • 16
    • 0029666413 scopus 로고    scopus 로고
    • The apolipoprotein E ε4 allele is associated with increased neuritic plaques and cerebral amyloid angiopathy in Alzheimer's disease and Lewy body variant
    • Olichney JM, Hansen LA, Galasko D, et al. The apolipoprotein E ε4 allele is associated with increased neuritic plaques and cerebral amyloid angiopathy in Alzheimer's disease and Lewy body variant. Neurology. 1996;47:190-196.
    • (1996) Neurology , vol.47 , pp. 190-196
    • Olichney, J.M.1    Hansen, L.A.2    Galasko, D.3
  • 17
    • 0027517625 scopus 로고
    • Plaque-only Alzheimer's disease is usually the Lewy body variant, and vice versa
    • Hansen LA, Masliah E, Galasko D, Terry RD. Plaque-only Alzheimer's disease is usually the Lewy body variant, and vice versa. J Neuropathol Exp Neurol. 1993;52:648-654.
    • (1993) J Neuropathol Exp Neurol , vol.52 , pp. 648-654
    • Hansen, L.A.1    Masliah, E.2    Galasko, D.3    Terry, R.D.4
  • 18
    • 0020386060 scopus 로고
    • Mild senile dementia of Alzheimer type: Research Diagnostic Criteria, recruitment, and description of a study population
    • Berg L, Hughes CP, Coben LA, et al. Mild senile dementia of Alzheimer type: Research Diagnostic Criteria, recruitment, and description of a study population. J Neurol Neurosurg Psychiatry. 1982;45:962-968.
    • (1982) J Neurol Neurosurg Psychiatry , vol.45 , pp. 962-968
    • Berg, L.1    Hughes, C.P.2    Coben, L.A.3
  • 19
    • 0021271971 scopus 로고
    • Clinical diagnosis of Alzheimer's disease: Report of the NINCDS/ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease
    • McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan AM. Clinical diagnosis of Alzheimer's disease: report of the NINCDS/ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology. 1984;34:939-944.
    • (1984) Neurology , vol.34 , pp. 939-944
    • McKhann, G.1    Drachman, D.2    Folstein, M.3    Katzman, R.4    Price, D.5    Stadlan, A.M.6
  • 20
    • 0028174629 scopus 로고
    • Graham DI. β-Amyloid protein deposition in the brain after severe head injury: Implications for the pathogenesis of Alzheimer's disease
    • Roberts GW, Gentleman SM, Lynch A, Murray L, Landon M, Graham DI. β-Amyloid protein deposition in the brain after severe head injury: implications for the pathogenesis of Alzheimer's disease. J Neurol Neurosurg Psychiatry. 1994;57:419-425.
    • (1994) J Neurol Neurosurg Psychiatry , vol.57 , pp. 419-425
    • Roberts, G.W.1    Gentleman, S.M.2    Lynch, A.3    Murray, L.4    Landon, M.5
  • 23
    • 0020040238 scopus 로고
    • A new clinical scale for the staging of dementia
    • Hughes CP, Berg L, Danziger WL, et al. A new clinical scale for the staging of dementia. Br J Psychiatry. 1982;140:566-572.
    • (1982) Br J Psychiatry , vol.140 , pp. 566-572
    • Hughes, C.P.1    Berg, L.2    Danziger, W.L.3
  • 24
    • 0027425211 scopus 로고
    • The Clinical Dementia Rating (CDR): Current version and scoring rules
    • Morris JC. The Clinical Dementia Rating (CDR): current version and scoring rules. Neurology. 1993;43:2412-2414.
    • (1993) Neurology , vol.43 , pp. 2412-2414
    • Morris, J.C.1
  • 25
    • 0023923356 scopus 로고
    • Mild senile dementia of the Alzheimer type, 2: Longitudinal assessment
    • Berg L, Miller JP, Storandt M, et al. Mild senile dementia of the Alzheimer type, 2: longitudinal assessment. Ann Neurol. 1988;23:477-484.
    • (1988) Ann Neurol , vol.23 , pp. 477-484
    • Berg, L.1    Miller, J.P.2    Storandt, M.3
  • 26
    • 0023860893 scopus 로고
    • Reliability of the Washington University Clinical Dementia Rating (CDR)
    • Burke WJ, Miller JP, Rubin EH, et al. Reliability of the Washington University Clinical Dementia Rating (CDR). Arch Neurol. 1988;45:31-32.
    • (1988) Arch Neurol , vol.45 , pp. 31-32
    • Burke, W.J.1    Miller, J.P.2    Rubin, E.H.3
  • 28
    • 0025822216 scopus 로고
    • Retrospective postmortem dementia assessment: Validation of a new clinical interview to assist neuropathologic study
    • Davis PB, White H, Price JL, McKeel DW, Robins LN. Retrospective postmortem dementia assessment: validation of a new clinical interview to assist neuropathologic study. Arch Neurol. 1991;48:613-617.
    • (1991) Arch Neurol , vol.48 , pp. 613-617
    • Davis, P.B.1    White, H.2    Price, J.L.3    McKeel, D.W.4    Robins, L.N.5
  • 30
    • 0025770134 scopus 로고
    • The distribution of tangles, plaques and related immunohistochemical markers in healthy aging and Alzheimer's disease
    • Price JL, Davis PB, Morris JC, White DL. The distribution of tangles, plaques and related immunohistochemical markers in healthy aging and Alzheimer's disease. Neurobiol Aging. 1991;12:295-312.
    • (1991) Neurobiol Aging , vol.12 , pp. 295-312
    • Price, J.L.1    Davis, P.B.2    Morris, J.C.3    White, D.L.4
  • 31
    • 0028639536 scopus 로고
    • Tangles and plaques in healthy aging and Alzheimer's disease: Independence or interaction?
    • Price JL. Tangles and plaques in healthy aging and Alzheimer's disease: independence or interaction? Semin Neurosci. 1994;6:395-402.
    • (1994) Semin Neurosci , vol.6 , pp. 395-402
    • Price, J.L.1
  • 32
    • 0025257612 scopus 로고
    • Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with Hha 1
    • Hixson JE, Vernier DT. Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with Hha 1. J Lipid Res. 1990;31:545-548.
    • (1990) J Lipid Res , vol.31 , pp. 545-548
    • Hixson, J.E.1    Vernier, D.T.2
  • 33
    • 0029867041 scopus 로고    scopus 로고
    • Polymorphism in AACT gene may lower age of onset of Alzheimer's disease
    • Talbot C, Houlden H, Craddock N, et al. Polymorphism in AACT gene may lower age of onset of Alzheimer's disease. Neuroreport. 1996;7:534-536.
    • (1996) Neuroreport , vol.7 , pp. 534-536
    • Talbot, C.1    Houlden, H.2    Craddock, N.3
  • 34
    • 0029396979 scopus 로고
    • Alzheimer's disease with and without coexisting Parkinson's disease changes: Apolipoprotein E genotype and neuropathologic correlates
    • Gearing M, Schneider JA, Rebeck GW, Hyman BT, Mirra SS. Alzheimer's disease with and without coexisting Parkinson's disease changes: apolipoprotein E genotype and neuropathologic correlates. Neurology. 1995;45:1985-1990.
    • (1995) Neurology , vol.45 , pp. 1985-1990
    • Gearing, M.1    Schneider, J.A.2    Rebeck, G.W.3    Hyman, B.T.4    Mirra, S.S.5
  • 35
    • 0029031943 scopus 로고
    • Frequent loss of heterozygosity on 6q at the mannose 6-phosphate/insulin-like growth factor II receptor locus in human hepatocellular tumors
    • De Souza AT, Hankins GR, Washington MK, Fine RL, Orton TC, Jirtle RL. Frequent loss of heterozygosity on 6q at the mannose 6-phosphate/insulin-like growth factor II receptor locus in human hepatocellular tumors. Oncogene. 1995;10:1725-1729.
    • (1995) Oncogene , vol.10 , pp. 1725-1729
    • De Souza, A.T.1    Hankins, G.R.2    Washington, M.K.3    Fine, R.L.4    Orton, T.C.5    Jirtle, R.L.6
  • 36
    • 0023795599 scopus 로고
    • Selective silver impregnation of senile plaques: A method useful for computer imaging
    • Hedreen JC, Raskin LS, Struble RG, Price DL. Selective silver impregnation of senile plaques: a method useful for computer imaging. J Neurosci Methods. 1988;25:151-158.
    • (1988) J Neurosci Methods , vol.25 , pp. 151-158
    • Hedreen, J.C.1    Raskin, L.S.2    Struble, R.G.3    Price, D.L.4
  • 37
    • 0030938688 scopus 로고    scopus 로고
    • Automated identification and quantitative morphometry of the senile plaques of Alzheimer's disease
    • Hibbard LS, McKeel DW Jr. Automated identification and quantitative morphometry of the senile plaques of Alzheimer's disease. Analyt Quant Cytol Histol. 1997;19:123-138.
    • (1997) Analyt Quant Cytol Histol , vol.19 , pp. 123-138
    • Hibbard, L.S.1    McKeel Jr., D.W.2
  • 38
    • 0022414054 scopus 로고
    • Diagnosis of Alzheimer's disease
    • Khacnaturian ZS. Diagnosis of Alzheimer's disease. Arch Neurol. 1985;42:1097-1105.
    • (1985) Arch Neurol , vol.42 , pp. 1097-1105
    • Khacnaturian, Z.S.1
  • 39
    • 0030581111 scopus 로고    scopus 로고
    • Lewy bodies are located preferentially in limbic areas in diffuse Lewy body disease
    • Rezaie P, Cairns NJ, Chadwick A, Lantos PL. Lewy bodies are located preferentially in limbic areas in diffuse Lewy body disease. Neurosci Lett. 1996;212:111-114.
    • (1996) Neurosci Lett , vol.212 , pp. 111-114
    • Rezaie, P.1    Cairns, N.J.2    Chadwick, A.3    Lantos, P.L.4
  • 41
    • 0000882795 scopus 로고
    • Extension of the multiple range tests to group means with unequal numbers of replications
    • Kramer CY. Extension of the multiple range tests to group means with unequal numbers of replications. Biometrics. 1956;12:309-310.
    • (1956) Biometrics , vol.12 , pp. 309-310
    • Kramer, C.Y.1
  • 42
    • 0028174753 scopus 로고
    • An extensive network of PHF tau-rich dystrophic neuntes permeates neocortex and nearly all neuritic and diffuse amyloid plaques in Alzheimer disease
    • Schmidt ML, DiDario AG, Lee VM-Y, Trojanowski JQ. An extensive network of PHF tau-rich dystrophic neuntes permeates neocortex and nearly all neuritic and diffuse amyloid plaques in Alzheimer disease. FEBS Lett. 1994;344:69-73.
    • (1994) FEBS Lett , vol.344 , pp. 69-73
    • Schmidt, M.L.1    DiDario, A.G.2    Lee, V.M.-Y.3    Trojanowski, J.Q.4
  • 43
    • 0025773225 scopus 로고
    • Neuritic pathology and dementia in Alzheimer's disease
    • McKee AC, Kosik KS, Kowall NW. Neuritic pathology and dementia in Alzheimer's disease. Ann Neurol. 1991;30:156-165.
    • (1991) Ann Neurol , vol.30 , pp. 156-165
    • McKee, A.C.1    Kosik, K.S.2    Kowall, N.W.3
  • 44
    • 0026740795 scopus 로고
    • Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease
    • Arriagada PV, Growdon JH, Hedley-Whyte ET, Hyman BT. Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease, Neurology. 1992;42:631-639.
    • (1992) Neurology , vol.42 , pp. 631-639
    • Arriagada, P.V.1    Growdon, J.H.2    Hedley-Whyte, E.T.3    Hyman, B.T.4
  • 45
    • 0027490070 scopus 로고
    • The lack of accumulation of senile plaques or amyloid burden in Alzheimer's disease suggests a dynamic balance between amyloid deposition and resolution
    • Hyman BT, Marzloff K, Arriagada PV. The lack of accumulation of senile plaques or amyloid burden in Alzheimer's disease suggests a dynamic balance between amyloid deposition and resolution. J Neuropathol Exp Neurol. 1993;52:594-600.
    • (1993) J Neuropathol Exp Neurol , vol.52 , pp. 594-600
    • Hyman, B.T.1    Marzloff, K.2    Arriagada, P.V.3
  • 46
    • 0028132966 scopus 로고
    • Clinical correlates of cortical and nucleus basalis pathology in Alzheimer dementia
    • Samuel W, Terry RD, DeTeresa R, Butters N, Masliah E. Clinical correlates of cortical and nucleus basalis pathology in Alzheimer dementia. Arch Neurol. 1994;51:772-778.
    • (1994) Arch Neurol , vol.51 , pp. 772-778
    • Samuel, W.1    Terry, R.D.2    DeTeresa, R.3    Butters, N.4    Masliah, E.5
  • 48
    • 0028799250 scopus 로고
    • Differential correlation between neurochemical deficits, neuropathology, and cognitive status in Alzheimer's disease
    • Dournaud P, DeLaére P, Hauw JJ, Epelbaum J. Differential correlation between neurochemical deficits, neuropathology, and cognitive status in Alzheimer's disease. Neurobiol Aging. 1995;16:817-823.
    • (1995) Neurobiol Aging , vol.16 , pp. 817-823
    • Dournaud, P.1    Delaére, P.2    Hauw, J.J.3    Epelbaum, J.4
  • 49
    • 0028861585 scopus 로고
    • Neocortical neurofibrillary tangles correlate with dementia severity in Alzheimer's disease
    • Bierer LM, Hof PR, Dushyant PP, et al. Neocortical neurofibrillary tangles correlate with dementia severity in Alzheimer's disease. Arch Neurol. 1995;52:81-88.
    • (1995) Arch Neurol , vol.52 , pp. 81-88
    • Bierer, L.M.1    Hof, P.R.2    Dushyant, P.P.3
  • 50
    • 0030050286 scopus 로고    scopus 로고
    • Clinical and pathological correlates of apolipoprotein E ε4 in Alzheimer's disease
    • Gómez-Isla T, West HL, Rebeck GW, et al. Clinical and pathological correlates of apolipoprotein E ε4 in Alzheimer's disease. Ann Neurol. 1996;39:62-70.
    • (1996) Ann Neurol , vol.39 , pp. 62-70
    • Gómez-Isla, T.1    West, H.L.2    Rebeck, G.W.3
  • 51
    • 0344653664 scopus 로고    scopus 로고
    • Neuronal loss correlates with but exceeds neurofibrillary tangles in Alzheimer's disease
    • Gómez-Isla T, Hollister R, West H, et al. Neuronal loss correlates with but exceeds neurofibrillary tangles in Alzheimer's disease. Ann Neurol. 1997;41:17-24.
    • (1997) Ann Neurol , vol.41 , pp. 17-24
    • Gómez-Isla, T.1    Hollister, R.2    West, H.3
  • 52
    • 0030464914 scopus 로고    scopus 로고
    • Cotman CW. β-Amyloid deposition and other measures of neuropathology predict cognitive status in Alzheimer's disease
    • Cummings BJ, Pike CJ, Shankle R, Cotman CW. β-Amyloid deposition and other measures of neuropathology predict cognitive status in Alzheimer's disease. Neurobiol Aging. 1996;17:921-933.
    • (1996) Neurobiol Aging , vol.17 , pp. 921-933
    • Cummings, B.J.1    Pike, C.J.2    Shankle, R.3
  • 53
    • 0014313861 scopus 로고
    • The association between quantitative measures of dementia and of senile changes in the cerebral grey matter of elderly subjects
    • Blessed G, Tomlinson BE, Roth M. The association between quantitative measures of dementia and of senile changes in the cerebral grey matter of elderly subjects. Br J Psychiatry. 1968;114:797-811.
    • (1968) Br J Psychiatry , vol.114 , pp. 797-811
    • Blessed, G.1    Tomlinson, B.E.2    Roth, M.3
  • 54
    • 0029795197 scopus 로고    scopus 로고
    • The pathogenesis of Alzheimer disease: An alternative to the amyloid hypothesis
    • Terry RD. The pathogenesis of Alzheimer disease: an alternative to the amyloid hypothesis. J Neuropathol Exp Neurol. 1996;55:1023-1025.
    • (1996) J Neuropathol Exp Neurol , vol.55 , pp. 1023-1025
    • Terry, R.D.1
  • 55
    • 0025987048 scopus 로고
    • Physical basis of cognitive alterations in Alzheimer's disease: Synapse loss is the major correlate of cognitive impairment
    • Terry RD, Masliah E, Salmon DP, et al. Physical basis of cognitive alterations in Alzheimer's disease: synapse loss is the major correlate of cognitive impairment. Ann Neurol. 1991;30:572-580.
    • (1991) Ann Neurol , vol.30 , pp. 572-580
    • Terry, R.D.1    Masliah, E.2    Salmon, D.P.3
  • 56
    • 0029979798 scopus 로고    scopus 로고
    • Profound loss of layer II entorhinal cortex neurons occurs in very mild Alzheimer's disease
    • Gómez-Isla T, Price JL, McKeel DW, et al. Profound loss of layer II entorhinal cortex neurons occurs in very mild Alzheimer's disease. J Neurosci. 1996;16:4491-4500.
    • (1996) J Neurosci , vol.16 , pp. 4491-4500
    • Gómez-Isla, T.1    Price, J.L.2    McKeel, D.W.3
  • 57
    • 0029665096 scopus 로고    scopus 로고
    • Apolipoprotein E-ε4 alleles in cerebral amyloid angiopathy and cerebrovascular pathology associated with Alzheimer's disease
    • Premkumar DRD, Cohen DL, Hedera P, Friedland RP, Kalaria RN. Apolipoprotein E-ε4 alleles in cerebral amyloid angiopathy and cerebrovascular pathology associated with Alzheimer's disease. Am J Pathol. 1996;48:2083-2095.
    • (1996) Am J Pathol , vol.48 , pp. 2083-2095
    • Premkumar, D.R.D.1    Cohen, D.L.2    Hedera, P.3    Friedland, R.P.4    Kalaria, R.N.5
  • 58
    • 0030815773 scopus 로고    scopus 로고
    • The effects of additional pathology on the cognitive deficit in Alzheimer disease
    • Nagy Z, Esiri MM, Jobst KA, et al. The effects of additional pathology on the cognitive deficit in Alzheimer disease. J Neuropathol Exp Neurol. 1997;56:165-170.
    • (1997) J Neuropathol Exp Neurol , vol.56 , pp. 165-170
    • Nagy, Z.1    Esiri, M.M.2    Jobst, K.A.3
  • 60
  • 61
    • 0026503471 scopus 로고
    • Psychometric discrimination of moderate senile dementia of the Alzheimer type
    • Hill RD, Storandt M, LaBarge E. Psychometric discrimination of moderate senile dementia of the Alzheimer type. Arch Neurol. 1992;49:377-380.
    • (1992) Arch Neurol , vol.49 , pp. 377-380
    • Hill, R.D.1    Storandt, M.2    LaBarge, E.3
  • 62
    • 0024506466 scopus 로고
    • Very mild senile dementia of the Alzheimer type, II: Psychometric test performance
    • Storandt M, Hill RD. Very mild senile dementia of the Alzheimer type, II: psychometric test performance. Arch Neurol. 1989;46:383-386.
    • (1989) Arch Neurol , vol.46 , pp. 383-386
    • Storandt, M.1    Hill, R.D.2
  • 63
    • 0023175756 scopus 로고
    • Katzman R. Senile dementia of the Alzheimer type without neocortical neurofibrillary tangles
    • Terry RD, Hansen LA, DeTeresa R, Davies P, Tobias H. Katzman R. Senile dementia of the Alzheimer type without neocortical neurofibrillary tangles. J Neuropathol Exp Neurol. 1987;46:262-268.
    • (1987) J Neuropathol Exp Neurol , vol.46 , pp. 262-268
    • Terry, R.D.1    Hansen, L.A.2    DeTeresa, R.3    Davies, P.4    Tobias, H.5
  • 64
    • 0031035211 scopus 로고    scopus 로고
    • Criteria for Alzheimer's disease and the nosology of dementia with Lewy bodies
    • Hansen LA, Samuel W. Criteria for Alzheimer's disease and the nosology of dementia with Lewy bodies. Neurology. 1997;48:126-132.
    • (1997) Neurology , vol.48 , pp. 126-132
    • Hansen, L.A.1    Samuel, W.2
  • 65
    • 0029396761 scopus 로고
    • CERAD part IX: A prospective cliniconeuropathologic study of Parkinson's features in Alzheimer's disease
    • Hulette C, Mirra SS, Wilkinson W, Heyman A, Fillenbaum G. Clark CM. CERAD part IX: a prospective cliniconeuropathologic study of Parkinson's features in Alzheimer's disease. Neurology. 1995;45:1991-1995.
    • (1995) Neurology , vol.45 , pp. 1991-1995
    • Hulette, C.1    Mirra, S.S.2    Wilkinson, W.3    Heyman, A.4    Fillenbaum, G.5    Clark, C.M.6
  • 66
    • 0028305380 scopus 로고
    • Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease
    • Corder EH, Saunders AM, Risch NJ, et al. Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease. Nat Genet. 1994;7:180-184.
    • (1994) Nat Genet , vol.7 , pp. 180-184
    • Corder, E.H.1    Saunders, A.M.2    Risch, N.J.3
  • 67
    • 0028169648 scopus 로고
    • Reduced apolipoprotein ε4 allele frequency in the oldest old Alzheimer's patients and cognitively normal individuals
    • [published correction appears in Neurology. 1995;45:598].
    • Rebeck GW, Perls TT, West HL, Sodhi P, Lipsitz LA, Hyman BT. Reduced apolipoprotein ε4 allele frequency in the oldest old Alzheimer's patients and cognitively normal individuals [published correction appears in Neurology. 1995;45:598]. Neurology. 1994;44:1513-1516.
    • (1994) Neurology , vol.44 , pp. 1513-1516
    • Rebeck, G.W.1    Perls, T.T.2    West, H.L.3    Sodhi, P.4    Lipsitz, L.A.5    Hyman, B.T.6
  • 68
    • 0029118904 scopus 로고
    • Apolipoprotein E, survival in Alzheimer's disease patients, and the competing risks of death and Alzheimer's disease
    • Corder EH, Saunders AM, Strittmatter WJ, et al. Apolipoprotein E, survival in Alzheimer's disease patients, and the competing risks of death and Alzheimer's disease. Neurology. 1995;45:1323-1328.
    • (1995) Neurology , vol.45 , pp. 1323-1328
    • Corder, E.H.1    Saunders, A.M.2    Strittmatter, W.J.3
  • 69
    • 0029037609 scopus 로고
    • Lack of association of apolipoprotein E allele ε4 with late-onset Alzheimer's disease among Finnish centenarians
    • Sobel E, Louhija J, Sulkava R, et al. Lack of association of apolipoprotein E allele ε4 with late-onset Alzheimer's disease among Finnish centenarians. Neurology. 1995;45:903-907.
    • (1995) Neurology , vol.45 , pp. 903-907
    • Sobel, E.1    Louhija, J.2    Sulkava, R.3
  • 70
    • 0028880320 scopus 로고
    • Effect of apolipoprotein E genotype on Alzheimer's disease neuropathology in a cohort of elderly Norwegians
    • Morris CM, Benjamin R, Leake A, et al. Effect of apolipoprotein E genotype on Alzheimer's disease neuropathology in a cohort of elderly Norwegians. Neurosci Lett. 1995;201:45-47.
    • (1995) Neurosci Lett , vol.201 , pp. 45-47
    • Morris, C.M.1    Benjamin, R.2    Leake, A.3
  • 71
    • 0029942993 scopus 로고    scopus 로고
    • APOE alleles in Alzheimer's disease and vascular dementia in a population aged 85+
    • Sulkava R, Kainulainen K, Verkkoniemi A, et al. APOE alleles in Alzheimer's disease and vascular dementia in a population aged 85+. Neurobiol Aging. 1996;17:373-376.
    • (1996) Neurobiol Aging , vol.17 , pp. 373-376
    • Sulkava, R.1    Kainulainen, K.2    Verkkoniemi, A.3
  • 72
    • 17744410836 scopus 로고    scopus 로고
    • ApoE-4 and age at onset of Alzheimer's disease: The NIMH Genetics Initiative
    • Blacker D, Haines JL, Rodes L, et al. ApoE-4 and age at onset of Alzheimer's disease: the NIMH Genetics Initiative. Neurology. 1997;48:139-147.
    • (1997) Neurology , vol.48 , pp. 139-147
    • Blacker, D.1    Haines, J.L.2    Rodes, L.3
  • 73
    • 0028841027 scopus 로고
    • Apolipoprotein E, dementia, and cortical deposition of β-amyloid protein
    • Polvikoski T, Sulkava R, Haltia M, et al. Apolipoprotein E, dementia, and cortical deposition of β-amyloid protein. N Engl J Med. 1995;333:1242-1247.
    • (1995) N Engl J Med , vol.333 , pp. 1242-1247
    • Polvikoski, T.1    Sulkava, R.2    Haltia, M.3
  • 74
    • 0029664434 scopus 로고    scopus 로고
    • Aβ-peptide length and apolipoprotein E genotype in Alzheimer's disease
    • Gearing M, Mori H, Mirra SS. Aβ-peptide length and apolipoprotein E genotype in Alzheimer's disease. Ann Neurol. 1996;39:395-399.
    • (1996) Ann Neurol , vol.39 , pp. 395-399
    • Gearing, M.1    Mori, H.2    Mirra, S.S.3
  • 75
    • 0029762447 scopus 로고    scopus 로고
    • Alzheimer's disease and apolioprotein E genotype in western Australia: An autopsy-verified series
    • Fabian VA, Jones TM, Wilton SD, et al. Alzheimer's disease and apolioprotein E genotype in western Australia: an autopsy-verified series. Med J Aust. 1996;165:77-80.
    • (1996) Med J Aust , vol.165 , pp. 77-80
    • Fabian, V.A.1    Jones, T.M.2    Wilton, S.D.3
  • 76
    • 0029857204 scopus 로고    scopus 로고
    • The apolipoprotein E allele ε4 does not correlate with the number of senile plaques or neurofibrillary tangles in patients with Alzheimer's disease
    • Landén M, Throsell A, Wallin A, Blennow K. The apolipoprotein E allele ε4 does not correlate with the number of senile plaques or neurofibrillary tangles in patients with Alzheimer's disease. J Neurol Neurosurg Psychiatry. 1996;61:352-356.
    • (1996) J Neurol Neurosurg Psychiatry , vol.61 , pp. 352-356
    • Landén, M.1    Throsell, A.2    Wallin, A.3    Blennow, K.4
  • 77
    • 0031046146 scopus 로고    scopus 로고
    • Apolipoprotein E genotype and amyloid load in Alzheimer disease and control brains
    • Pirttilä T, Soininen H, Mehta PD, et al. Apolipoprotein E genotype and amyloid load in Alzheimer disease and control brains. Neurobiol Aging. 1997;18:121-127.
    • (1997) Neurobiol Aging , vol.18 , pp. 121-127
    • Pirttilä, T.1    Soininen, H.2    Mehta, P.D.3
  • 78
    • 0029146372 scopus 로고
    • Alzheimer pathology of patients carrying apolipoprotein E ε4 allele
    • Heinonen O, Lehtovirta M, Soininen H, et al. Alzheimer pathology of patients carrying apolipoprotein E ε4 allele. Neurobiol Aging. 1995;16:505-513.
    • (1995) Neurobiol Aging , vol.16 , pp. 505-513
    • Heinonen, O.1    Lehtovirta, M.2    Soininen, H.3
  • 81
    • 0028178047 scopus 로고
    • Apolipoprotein E ε4 allele as a major risk factor for sporadic early and late-onset form of Alzheimer's disease: Analysis of the 19q13.2 chromosomal region
    • Chartier-Harlin MC, Parfitt M, Legrain S, et al. Apolipoprotein E ε4 allele as a major risk factor for sporadic early and late-onset form of Alzheimer's disease: analysis of the 19q13.2 chromosomal region. Hum Mol Genet. 1994;3:569-574.
    • (1994) Hum Mol Genet , vol.3 , pp. 569-574
    • Chartier-Harlin, M.C.1    Parfitt, M.2    Legrain, S.3
  • 82
    • 0025908356 scopus 로고
    • The Consortium to Establish a Registry for Alzheimer's Disease (CERAD), part II: Standardization of the neuropathological assessment of Alzheimer's disease
    • Mirra SS, Heyman A, McKeel D, et al. The Consortium to Establish a Registry for Alzheimer's Disease (CERAD), part II: standardization of the neuropathological assessment of Alzheimer's disease. Neurology. 1991;41:479-486.
    • (1991) Neurology , vol.41 , pp. 479-486
    • Mirra, S.S.1    Heyman, A.2    McKeel, D.3
  • 84
    • 0029058370 scopus 로고
    • Cognitive impairment in the nondemented elderly
    • Ebly EM, Hogan DB, Parhad IM. Cognitive impairment in the nondemented elderly. Arch Neurol. 1995;52:612-619.
    • (1995) Arch Neurol , vol.52 , pp. 612-619
    • Ebly, E.M.1    Hogan, D.B.2    Parhad, I.M.3
  • 85
    • 0030681215 scopus 로고    scopus 로고
    • Consensus recommendations for the postmortem diagnosis of Alzheimer's disease
    • The National Institute on Aging and Reagan Institute Working Group on Diagnostic Criteria for the Neuropathological Assessment of Alzheimer's Disease. Consensus recommendations for the postmortem diagnosis of Alzheimer's disease. Neurobiol Aging. 1997;18(4S):S1-S105.
    • (1997) Neurobiol Aging , vol.18 , Issue.4 S
  • 86
    • 0030681218 scopus 로고    scopus 로고
    • Diagnostic criteria for Alzheimer's disease: Position paper
    • Price JL. Diagnostic criteria for Alzheimer's disease: position paper. Neurobiol Aging. 1997;18(4S):S67-S70.
    • (1997) Neurobiol Aging , vol.18 , Issue.4 S
    • Price, J.L.1
  • 87
    • 0002270783 scopus 로고
    • Diagnosis
    • Terry RD, Katzman R, Bick K, eds. New York, NY: Raven Press
    • Berg L, Morris JC. Diagnosis. In: Terry RD, Katzman R, Bick K, eds. Alzheimer Disease. New York, NY: Raven Press; 1994:9-25.
    • (1994) Alzheimer Disease , pp. 9-25
    • Berg, L.1    Morris, J.C.2
  • 88
    • 0029056590 scopus 로고
    • CERAD part X: Neuropathology confirmation of the clinical diagnosis of Alzheimer's disease
    • Gearing M, Mirra SS, Sumi M, Hansen L, Hedreen J, Heyman A. CERAD part X: neuropathology confirmation of the clinical diagnosis of Alzheimer's disease. Neurology. 1995;45:461-466.
    • (1995) Neurology , vol.45 , pp. 461-466
    • Gearing, M.1    Mirra, S.S.2    Sumi, M.3    Hansen, L.4    Hedreen, J.5    Heyman, A.6
  • 89
    • 0029824174 scopus 로고    scopus 로고
    • Accuracy of clinical diagnosis of Alzheimer disease and clinical features of patients with non-Alzheimer disease neuropathology
    • Rasmusson DX, Brandt J, Steele C, Hedreen JC, Troncoso JC, Folstein MF. Accuracy of clinical diagnosis of Alzheimer disease and clinical features of patients with non-Alzheimer disease neuropathology. Alzheimer Dis Assoc Disord. 1996;10:180-188.
    • (1996) Alzheimer Dis Assoc Disord , vol.10 , pp. 180-188
    • Rasmusson, D.X.1    Brandt, J.2    Steele, C.3    Hedreen, J.C.4    Troncoso, J.C.5    Folstein, M.F.6
  • 90
    • 0022902782 scopus 로고
    • Mesolimbocorticaldementia
    • Torack RM, Morris JC. Mesolimbocorticaldementia. Arch Neurol. 1986;43:1074-1078.
    • (1986) Arch Neurol , vol.43 , pp. 1074-1078
    • Torack, R.M.1    Morris, J.C.2
  • 91
    • 0027432101 scopus 로고
    • Pathological markers associated with normal aging and dementia in the elderly
    • Crystal HA, Dickson DW, Sliwinski MJ, et al. Pathological markers associated with normal aging and dementia in the elderly. Ann Neurol. 1993;34:566-573.
    • (1993) Ann Neurol , vol.34 , pp. 566-573
    • Crystal, H.A.1    Dickson, D.W.2    Sliwinski, M.J.3
  • 92
    • 0028086345 scopus 로고
    • Hippocampal sclerosis: A common pathological feature in very old (≥80 years of age) humans
    • Dickson DW, Davies P, Bevona C, et al. Hippocampal sclerosis: a common pathological feature in very old (≥80 years of age) humans. Acta Neuropathol. 1994;88:212-221.
    • (1994) Acta Neuropathol , vol.88 , pp. 212-221
    • Dickson, D.W.1    Davies, P.2    Bevona, C.3
  • 93
    • 0031016806 scopus 로고    scopus 로고
    • Hippocampal sclerosis contributes to dementia in the elderly
    • Corey-Bloom J, Sabbagh MN, Bondi MW, et al. Hippocampal sclerosis contributes to dementia in the elderly. Neurology. 1997;48:154-160.
    • (1997) Neurology , vol.48 , pp. 154-160
    • Corey-Bloom, J.1    Sabbagh, M.N.2    Bondi, M.W.3
  • 94
    • 0029895870 scopus 로고    scopus 로고
    • Neuropathology in controls and demented subjects from the Baltimore Longitudinal Study of Aging
    • Troncoso JC, Martin LJ, Dal Forno G, Kawas CH. Neuropathology in controls and demented subjects from the Baltimore Longitudinal Study of Aging. Neurobiol Aging. 1996;17:365-371.
    • (1996) Neurobiol Aging , vol.17 , pp. 365-371
    • Troncoso, J.C.1    Martin, L.J.2    Dal Forno, G.3    Kawas, C.H.4
  • 95
    • 0006164301 scopus 로고    scopus 로고
    • Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): Report of the Consortium on DLB International Workshop
    • McKeith IG, Galasko D, Kosaka K, et al. Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): report of the Consortium on DLB International Workshop. Neurology. 1996;47:1113-1124.
    • (1996) Neurology , vol.47 , pp. 1113-1124
    • McKeith, I.G.1    Galasko, D.2    Kosaka, K.3
  • 96
    • 0031026460 scopus 로고    scopus 로고
    • Accuracy of the clinical diagnosis of corticobasal degeneration: A clinicopathologic study
    • Litvan I, Agid Y, Goetz C, et al. Accuracy of the clinical diagnosis of corticobasal degeneration: a clinicopathologic study. Neurology. 1997;48:119-125.
    • (1997) Neurology , vol.48 , pp. 119-125
    • Litvan, I.1    Agid, Y.2    Goetz, C.3
  • 97
    • 0027985802 scopus 로고
    • Neurofibrillary tangle predominant form of senile dementia of Alzheimer type: A rare subtype in very old subjects
    • Bancher C, Jellinger KA. Neurofibrillary tangle predominant form of senile dementia of Alzheimer type: a rare subtype in very old subjects. Acta Neuropathol. 1994;88:567-570.
    • (1994) Acta Neuropathol , vol.88 , pp. 567-570
    • Bancher, C.1    Jellinger, K.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.