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Volumn 136, Issue 10, 2013, Pages 3004-3017

Alterations in α4β2 nicotinic receptors in cognitive decline in Alzheimer's aetiopathology

Author keywords

Alzheimer's disease; amyloid deposition; cognitive decline; positron emission tomography; 4 2 nicotinic receptor

Indexed keywords

AMYLOID BETA PROTEIN; CARBON 11; FLUORINE 18; NICOTINIC RECEPTOR ALPHA4BETA2; PITTSBURGH COMPOUND B;

EID: 84884840216     PISSN: 00068950     EISSN: 14602156     Source Type: Journal    
DOI: 10.1093/brain/awt195     Document Type: Article
Times cited : (65)

References (69)
  • 1
    • 0037145719 scopus 로고    scopus 로고
    • Impairment of cholinergic neurotransmission in adult and aged transgenic Tg2576 mouse brain expressing the Swedish mutation of human beta-amyloid precursor protein
    • Apelt J, Kumar A, Schliebs R. Impairment of cholinergic neurotransmission in adult and aged transgenic Tg2576 mouse brain expressing the Swedish mutation of human beta-amyloid precursor protein. Brain Res 2002; 953: 17-30.
    • (2002) Brain Res , vol.953 , pp. 17-30
    • Apelt, J.1    Kumar, A.2    Schliebs, R.3
  • 2
    • 0036810329 scopus 로고    scopus 로고
    • Alzheimer's disease and the basal forebrain cholinergic system: Relations to beta-amyloid peptides, cognition, and treatment strategies
    • Auld DS, Kornecook TJ, Bastianetto S, Quirion R. Alzheimer's disease and the basal forebrain cholinergic system: relations to beta-amyloid peptides, cognition, and treatment strategies. Prog Neurobiol 2002; 68: 209-45.
    • (2002) Prog Neurobiol , vol.68 , pp. 209-245
    • Auld, D.S.1    Kornecook, T.J.2    Bastianetto, S.3    Quirion, R.4
  • 3
    • 0038771243 scopus 로고    scopus 로고
    • Co-expression of alpha7 and beta2 nicotinic acetylcholine receptor subunit mRNAs within rat brain cholinergic neurons
    • Azam L, Winzer-Serhan U, Leslie FM. Co-expression of alpha7 and beta2 nicotinic acetylcholine receptor subunit mRNAs within rat brain cholinergic neurons. Neuroscience 2003; 119: 965-77.
    • (2003) Neuroscience , vol.119 , pp. 965-977
    • Azam, L.1    Winzer-Serhan, U.2    Leslie, F.M.3
  • 5
    • 0042735047 scopus 로고    scopus 로고
    • The cholinergic basal forebrain system during development and its influence on cognitive processes: Important questions and potential answers
    • Berger-Sweeney J. The cholinergic basal forebrain system during development and its influence on cognitive processes: important questions and potential answers. Neurosci Biobehav Rev 2003; 27: 401-11.
    • (2003) Neurosci Biobehav Rev , vol.27 , pp. 401-411
    • Berger-Sweeney, J.1
  • 8
    • 0029080035 scopus 로고
    • Improvement in performance of a delayed matching-tosample task by monkeys following ABT-418: A novel cholinergic channel activator for memory enhancement
    • Buccafusco JJ, Jackson WJ, Terry AV Jr, Marsh KC, Decker MW, Arneric SP. Improvement in performance of a delayed matching-tosample task by monkeys following ABT-418: a novel cholinergic channel activator for memory enhancement. Psychopharmacol 1995; 120: 256-66.
    • (1995) Psychopharmacol , vol.120 , pp. 256-266
    • Buccafusco, J.J.1    Jackson, W.J.2    Terry Jr., A.V.3    Marsh, K.C.4    Decker, M.W.5    Arneric, S.P.6
  • 9
    • 23944444806 scopus 로고    scopus 로고
    • Molecular, structural, and functional characterization of Alzheimer's disease: Evidence for a relationship between default activity, amyloid, and memory
    • Buckner RL, Snyder AZ, Shannon BJ, LaRossa G, Sachs R, Fotenos AF, et al. Molecular, structural, and functional characterization of Alzheimer's disease: evidence for a relationship between default activity, amyloid, and memory. J Neurosci 2005; 25: 7709-17.
    • (2005) J Neurosci , vol.25 , pp. 7709-7717
    • Buckner, R.L.1    Snyder, A.Z.2    Shannon, B.J.3    Larossa, G.4    Sachs, R.5    Fotenos, A.F.6
  • 10
    • 0037399615 scopus 로고    scopus 로고
    • Graphical analysis of 2-[18F] FA binding to nicotinic acetylcholine receptors in rhesus monkey brain
    • Chefer SI, London ED, Koren AO, Pavlova OA, Kurian V, Kimes AS, et al. Graphical analysis of 2-[18F]FA binding to nicotinic acetylcholine receptors in rhesus monkey brain. Synapse 2003; 48: 25-34.
    • (2003) Synapse , vol.48 , pp. 25-34
    • Chefer, S.I.1    London, E.D.2    Koren, A.O.3    Pavlova, O.A.4    Kurian, V.5    Kimes, A.S.6
  • 12
    • 0033591017 scopus 로고    scopus 로고
    • Cholinergic markers in elderly patients with early signs of Alzheimer disease
    • Davis KL, Mohs RC, Marin D, Purohit DP, Perl DP, Lantz M, et al. Cholinergic markers in elderly patients with early signs of Alzheimer disease. JAMA 1999; 281: 1401-6.
    • (1999) JAMA , vol.281 , pp. 1401-1406
    • Davis, K.L.1    Mohs, R.C.2    Marin, D.3    Purohit, D.P.4    Perl, D.P.5    Lantz, M.6
  • 13
    • 33847137816 scopus 로고    scopus 로고
    • Effect of ispronicline, a neuronal nicotinic acetylcholine receptor partial agonist, in subjects with age associated memory impairment
    • Dunbar GC, Inglis F, Kuchibhatla R, Sharma T, Tomlinson M, Wamsley J. Effect of ispronicline, a neuronal nicotinic acetylcholine receptor partial agonist, in subjects with age associated memory impairment. J Psychopharmacol 2007; 21: 171-8.
    • (2007) J Psychopharmacol , vol.21 , pp. 171-178
    • Dunbar, G.C.1    Inglis, F.2    Kuchibhatla, R.3    Sharma, T.4    Tomlinson, M.5    Wamsley, J.6
  • 14
    • 3142583464 scopus 로고    scopus 로고
    • In the course of time: A PET study of the cerebral substrates of autobiographical amnesia in Alzheimer's disease
    • Eustache F, Piolino P, Giffard B, Viader F, De La Sayette V, Baron JC, et al. 'In the course of time': a PET study of the cerebral substrates of autobiographical amnesia in Alzheimer's disease. Brain 2004; 127: 1549-60.
    • (2004) Brain , vol.127 , pp. 1549-1560
    • Eustache, F.1    Piolino, P.2    Giffard, B.3    Viader, F.4    De La Sayette, V.5    Baron, J.C.6
  • 15
    • 15844383850 scopus 로고    scopus 로고
    • In vivo imaging of human cerebral nicotinic acetylcholine receptors with 2-18F-fluoro-A-85380 and PET
    • Gallezot JD, Bottlaender M, Gregoire MC, Roumenov D, Deverre JR, Coulon C, et al. In vivo imaging of human cerebral nicotinic acetylcholine receptors with 2-18F-fluoro-A-85380 and PET. J Nucl Med 2005; 46: 240-7.
    • (2005) J Nucl Med , vol.46 , pp. 240-247
    • Gallezot, J.D.1    Bottlaender, M.2    Gregoire, M.C.3    Roumenov, D.4    Deverre, J.R.5    Coulon, C.6
  • 16
    • 33747422892 scopus 로고    scopus 로고
    • Brain nicotinic acetylcholine receptors: Native subtypes and their relevance
    • Gotti C, Zoli M, Clementi F. Brain nicotinic acetylcholine receptors: native subtypes and their relevance. Trends Pharmacol Sci 2006; 27: 482-91.
    • (2006) Trends Pharmacol Sci , vol.27 , pp. 482-491
    • Gotti, C.1    Zoli, M.2    Clementi, F.3
  • 17
    • 0041922585 scopus 로고    scopus 로고
    • Executive and social behaviors under nicotinic receptor regulation
    • Granon S, Faure P, Changeux JP. Executive and social behaviors under nicotinic receptor regulation. Proc Nat Acad Sci USA 2003; 100: 9596-601.
    • (2003) Proc Nat Acad Sci USA , vol.100 , pp. 9596-9601
    • Granon, S.1    Faure, P.2    Changeux, J.P.3
  • 19
    • 80051605646 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptor b subunits in the medial prefrontal cortex control attention
    • Guillem K, Bloem B, Poorthuis RB, Loos M, Smit AB, Maskos U, et al. Nicotinic acetylcholine receptor b subunits in the medial prefrontal cortex control attention. Science 2011; 333: 888-91.
    • (2011) Science , vol.333 , pp. 888-891
    • Guillem, K.1    Bloem, B.2    Poorthuis, R.B.3    Loos, M.4    Smit, A.B.5    Maskos, U.6
  • 20
    • 0041665181 scopus 로고    scopus 로고
    • Involvement of the prefrontal cortex but not the dorsal hippocampus in the attention-enhancing effects of nicotine in rats
    • Hahn B, Shoaib M, Stolerman IP. Involvement of the prefrontal cortex but not the dorsal hippocampus in the attention-enhancing effects of nicotine in rats. Psychopharmacol 2003; 168: 271-9.
    • (2003) Psychopharmacol , vol.168 , pp. 271-279
    • Hahn, B.1    Shoaib, M.2    Stolerman, I.P.3
  • 21
    • 0021955153 scopus 로고
    • Nerve growth factor increases choline acetyltransferase but not survival or fiber outgrowth of cultured fetal septal cholinergic neurons
    • Hefti F, Hartikka J, Eckenstein F, Gnahn H, Heumann R, Schwab M. Nerve growth factor increases choline acetyltransferase but not survival or fiber outgrowth of cultured fetal septal cholinergic neurons. Neuroscience 1985; 14: 55-68.
    • (1985) Neuroscience , vol.14 , pp. 55-68
    • Hefti, F.1    Hartikka, J.2    Eckenstein, F.3    Gnahn, H.4    Heumann, R.5    Schwab, M.6
  • 22
    • 77951129733 scopus 로고    scopus 로고
    • Enhancement of attentional performance by selective stimulation of alpha4beta2(*) nAChRs: Underlying cholinergic mechanisms
    • Howe WM, Ji J, Parikh V, Williams S, Mocaer E, Trocme-Thibierge C, et al. Enhancement of attentional performance by selective stimulation of alpha4beta2(*) nAChRs: underlying cholinergic mechanisms. Neuropsychopharmacol 2010; 35: 1391-401.
    • (2010) Neuropsychopharmacol , vol.35 , pp. 1391-1401
    • Howe, W.M.1    Ji, J.2    Parikh, V.3    Williams, S.4    Mocaer, E.5    Trocme-Thibierge, C.6
  • 23
    • 80051520187 scopus 로고    scopus 로고
    • Precuneus amyloid burden is associated with reduced cholinergic activity in Alzheimer disease
    • Ikonomovic MD, Klunk WE, Abrahamson EE, Wuu J, Mathis CA, Scheff SW, et al. Precuneus amyloid burden is associated with reduced cholinergic activity in Alzheimer disease. Neurology 2011; 77: 39-47.
    • (2011) Neurology , vol.77 , pp. 39-47
    • Ikonomovic, M.D.1    Klunk, W.E.2    Abrahamson, E.E.3    Wuu, J.4    Mathis, C.A.5    Scheff, S.W.6
  • 24
    • 66549106850 scopus 로고    scopus 로고
    • Serial PIB and MRI in normal, mild cognitive impairment and Alzheimer's disease: Implications for sequence of pathological events in Alzheimer's disease
    • Jack CR Jr, Lowe VJ, Weigand SD, Wiste HJ, Senjem ML, Knopman DS, et al. Serial PIB and MRI in normal, mild cognitive impairment and Alzheimer's disease: implications for sequence of pathological events in Alzheimer's disease. Brain 2009; 132: 1355-65.
    • (2009) Brain , vol.132 , pp. 1355-1365
    • Jack Jr., C.R.1    Lowe, V.J.2    Weigand, S.D.3    Wiste, H.J.4    Senjem, M.L.5    Knopman, D.S.6
  • 25
    • 33947106934 scopus 로고    scopus 로고
    • Changes in brain 11C-nicotine binding sites in patients with mild Alzheimer's disease following rivastigmine treatment as assessed by PET
    • Kadir A, Darreh-Shori T, Almkvist O, Wall A, Langstrom B, Nordberg A. Changes in brain 11C-nicotine binding sites in patients with mild Alzheimer's disease following rivastigmine treatment as assessed by PET. Psychopharmacol 2007; 191: 1005-14.
    • (2007) Psychopharmacol , vol.191 , pp. 1005-1014
    • Kadir, A.1    Darreh-Shori, T.2    Almkvist, O.3    Wall, A.4    Langstrom, B.5    Nordberg, A.6
  • 26
    • 79953765442 scopus 로고    scopus 로고
    • Decreased cerebral alpha4beta2* nicotinic acetylcholine receptor availability in patients with mild cognitive impairment and Alzheimer's disease assessed with positron emission tomography
    • Kendziorra K, Wolf H, Meyer PM, Barthel H, Hesse S, Becker GA, et al. Decreased cerebral alpha4beta2* nicotinic acetylcholine receptor availability in patients with mild cognitive impairment and Alzheimer's disease assessed with positron emission tomography. Eur J Nucl Med Mol Imaging 2011; 38: 515-25.
    • (2011) Eur J Nucl Med Mol Imaging , vol.38 , pp. 515-525
    • Kendziorra, K.1    Wolf, H.2    Meyer, P.M.3    Barthel, H.4    Hesse, S.5    Becker, G.A.6
  • 27
    • 79961231805 scopus 로고    scopus 로고
    • Effects of brain amyloid deposition and reduced glucose metabolism on the default mode of brain function in normal aging
    • Kikuchi M, Hirosawa T, Yokokura M, Yagi S, Mori N, Yoshikawa E, et al. Effects of brain amyloid deposition and reduced glucose metabolism on the default mode of brain function in normal aging. J Neurosci 2011; 31: 11193-9.
    • (2011) J Neurosci , vol.31 , pp. 11193-11199
    • Kikuchi, M.1    Hirosawa, T.2    Yokokura, M.3    Yagi, S.4    Mori, N.5    Yoshikawa, E.6
  • 28
    • 0028051572 scopus 로고
    • Effects of blood flow on [11C]raclopride binding in the brain: Model simulations and kinetic analysis of PET data
    • Logan J, Volkow N D, et al. Effects of blood flow on [11C]raclopride binding in the brain: model simulations and kinetic analysis of PET data. J Cereb Blood Flow Metab 1994; 14: 995-1010.
    • (1994) J Cereb Blood Flow Metab , vol.14 , pp. 995-1010
    • Logan, J.1    Volkow, N.D.2
  • 30
    • 77950020286 scopus 로고    scopus 로고
    • Effects of the alpha4beta2 partial agonist varenicline on brain activity and working memory in abstinent smokers
    • Loughead J, Ray R, Wileyto EP, Ruparel K, Sanborn P, Siegel S, et al. Effects of the alpha4beta2 partial agonist varenicline on brain activity and working memory in abstinent smokers. Biol Psychiatry 2010; 67: 715-21.
    • (2010) Biol Psychiatry , vol.67 , pp. 715-721
    • Loughead, J.1    Ray, R.2    Wileyto, E.P.3    Ruparel, K.4    Sanborn, P.5    Siegel, S.6
  • 31
    • 0032888131 scopus 로고    scopus 로고
    • Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease
    • Lue LF, Kuo YM, Roher AE, Brachova L, Shen Y, Sue L, et al. Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease. Am J Pathol 1999; 155: 853-62.
    • (1999) Am J Pathol , vol.155 , pp. 853-862
    • Lue, L.F.1    Kuo, Y.M.2    Roher, A.E.3    Brachova, L.4    Shen, Y.5    Sue, L.6
  • 33
    • 0020642784 scopus 로고
    • Effects of chronic nicotine infusion on tolerance development and nicotinic receptors
    • Marks MJ, Burch JB, Collins AC. Effects of chronic nicotine infusion on tolerance development and nicotinic receptors. J Pharmacol Exp Ther 1983; 226: 817-25.
    • (1983) J Pharmacol Exp Ther , vol.226 , pp. 817-825
    • Marks, M.J.1    Burch, J.B.2    Collins, A.C.3
  • 34
    • 0036523105 scopus 로고    scopus 로고
    • Selective behavioral and neurochemical effects of cholinergic lesions produced by intrabasalis infusions of 192 IgG-saporin on attentional performance in a five-choice serial reaction time task
    • McGaughy J, Dalley JW, Morrison CH, Everitt BJ, Robbins TW. Selective behavioral and neurochemical effects of cholinergic lesions produced by intrabasalis infusions of 192 IgG-saporin on attentional performance in a five-choice serial reaction time task. J Neurosci 2002; 22: 1905-13.
    • (2002) J Neurosci , vol.22 , pp. 1905-1913
    • McGaughy, J.1    Dalley, J.W.2    Morrison, C.H.3    Everitt, B.J.4    Robbins, T.W.5
  • 35
    • 24944524929 scopus 로고    scopus 로고
    • Brain cholinergic vulnerability: Relevance to behavior and disease
    • McKinney M, Jacksonville MC. Brain cholinergic vulnerability: relevance to behavior and disease. Biochem Pharmacol 2005; 70: 1115-24.
    • (2005) Biochem Pharmacol , vol.70 , pp. 1115-1124
    • McKinney, M.1    Jacksonville, M.C.2
  • 36
    • 0032590054 scopus 로고    scopus 로고
    • Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease
    • McLean CA, Cherny RA, Fraser FW, Fuller SJ, Smith MJ, Beyreuther K, et al. Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease. Ann Neurol 1999; 46: 860-6.
    • (1999) Ann Neurol , vol.46 , pp. 860-866
    • McLean, C.A.1    Cherny, R.A.2    Fraser, F.W.3    Fuller, S.J.4    Smith, M.J.5    Beyreuther, K.6
  • 37
    • 0032780992 scopus 로고    scopus 로고
    • Assessment of spatial normalization of PET ligand images using ligand-specific templates
    • Meyer JH, Gunn RN, Myers R, Grasby PM. Assessment of spatial normalization of PET ligand images using ligand-specific templates. NeuroImage 1999; 9: 545-53.
    • (1999) NeuroImage , vol.9 , pp. 545-553
    • Meyer, J.H.1    Gunn, R.N.2    Myers, R.3    Grasby, P.M.4
  • 38
    • 68149126082 scopus 로고    scopus 로고
    • Reduced alpha4beta2*-nicotinic acetylcholine receptor binding and its relationship to mild cognitive and depressive symptoms in Parkinson disease
    • Meyer PM, Strecker K, Kendziorra K, Becker G, Hesse S, Woelpl D, et al. Reduced alpha4beta2*-nicotinic acetylcholine receptor binding and its relationship to mild cognitive and depressive symptoms in Parkinson disease. Arch Gen Psychiatry 2009; 66: 866-77.
    • (2009) Arch Gen Psychiatry , vol.66 , pp. 866-877
    • Meyer, P.M.1    Strecker, K.2    Kendziorra, K.3    Becker, G.4    Hesse, S.5    Woelpl, D.6
  • 39
    • 53749101043 scopus 로고    scopus 로고
    • Greater nicotinic acetylcholine receptor density in smokers than in nonsmokers: A PET study with 2-18F-FA-85380
    • Mukhin AG, Kimes AS, Chefer SI, Matochik JA, Contoreggi CS, Horti AG, et al. Greater nicotinic acetylcholine receptor density in smokers than in nonsmokers: a PET study with 2-18F-FA-85380. J Nucl Med 2008; 49: 1628-35.
    • (2008) J Nucl Med , vol.49 , pp. 1628-1635
    • Mukhin, A.G.1    Kimes, A.S.2    Chefer, S.I.3    Matochik, J.A.4    Contoreggi, C.S.5    Horti, A.G.6
  • 40
    • 0037066072 scopus 로고    scopus 로고
    • Intracellular accumulation of beta-amyloid(1-42) in neurons is facilitated by the alpha 7 nicotinic acetylcholine receptor in Alzheimer's disease
    • Nagele RG, D'Andrea MR, Anderson WJ, Wang HY. Intracellular accumulation of beta-amyloid(1-42) in neurons is facilitated by the alpha 7 nicotinic acetylcholine receptor in Alzheimer's disease. Neuroscience 2002; 110: 199-211.
    • (2002) Neuroscience , vol.110 , pp. 199-211
    • Nagele, R.G.1    D'andrea, M.R.2    Anderson, W.J.3    Wang, H.Y.4
  • 41
    • 0027031286 scopus 로고
    • Neuroreceptor changes in Alzheimer disease
    • Nordberg A. Neuroreceptor changes in Alzheimer disease. Cerebrovasc Brain Metab Rev 1992; 4: 303-28.
    • (1992) Cerebrovasc Brain Metab Rev , vol.4 , pp. 303-328
    • Nordberg, A.1
  • 43
    • 0032752306 scopus 로고    scopus 로고
    • Presynaptic and postsynaptic dopaminergic binding densities in the nigrostriatal and mesocortical systems in early Parkinson's disease: A double-tracer positron emission tomography study
    • Ouchi Y, Kanno T, Okada H, Yoshikawa E, Futatsubashi M, Nobezawa S, et al. Presynaptic and postsynaptic dopaminergic binding densities in the nigrostriatal and mesocortical systems in early Parkinson's disease: a double-tracer positron emission tomography study. Ann Neurol 1999; 46: 723-31.
    • (1999) Ann Neurol , vol.46 , pp. 723-731
    • Ouchi, Y.1    Kanno, T.2    Okada, H.3    Yoshikawa, E.4    Futatsubashi, M.5    Nobezawa, S.6
  • 45
    • 68249152023 scopus 로고    scopus 로고
    • Altered brain serotonin transporter and associated glucose metabolism in Alzheimer disease
    • Ouchi Y, Yoshikawa E, Futatsubashi M, Yagi S, Ueki T, Nakamura K. Altered brain serotonin transporter and associated glucose metabolism in Alzheimer disease. J Nucl Med 2009; 50: 1260-6.
    • (2009) J Nucl Med , vol.50 , pp. 1260-1266
    • Ouchi, Y.1    Yoshikawa, E.2    Futatsubashi, M.3    Yagi, S.4    Ueki, T.5    Nakamura, K.6
  • 46
    • 34748911259 scopus 로고    scopus 로고
    • Prefrontal acetylcholine release controls cue detection on multiple timescales
    • Parikh V, Kozak R, Martinez V, Sarter M. Prefrontal acetylcholine release controls cue detection on multiple timescales. Neuron 2007; 56: 141-54.
    • (2007) Neuron , vol.56 , pp. 141-154
    • Parikh, V.1    Kozak, R.2    Martinez, V.3    Sarter, M.4
  • 47
    • 0033964077 scopus 로고    scopus 로고
    • Neuronal nicotinic receptors in the human brain
    • Paterson D, Nordberg A. Neuronal nicotinic receptors in the human brain. Prog Neurobiol 2000; 61: 75-111.
    • (2000) Prog Neurobiol , vol.61 , pp. 75-111
    • Paterson, D.1    Nordberg, A.2
  • 48
    • 0017360731 scopus 로고
    • Necropsy evidence of central cholinergic deficits in senile dementia
    • Perry EK, Perry RH, Blessed G, Tomlinson BE. Necropsy evidence of central cholinergic deficits in senile dementia. Lancet 1977; 1: 189.
    • (1977) Lancet , vol.1 , pp. 189
    • Perry, E.K.1    Perry, R.H.2    Blessed, G.3    Tomlinson, B.E.4
  • 50
  • 51
    • 17144413330 scopus 로고
    • Abnormal avoidance learning in mice lacking functional high-affinity nicotine receptor in the brain
    • Picciotto MR, Zoli M, Lena C, Bessis A, Lallemand Y, Le Novere N, et al. Abnormal avoidance learning in mice lacking functional high-affinity nicotine receptor in the brain. Nature 1995; 374: 65-7.
    • (1995) Nature , vol.374 , pp. 65-67
    • Picciotto, M.R.1    Zoli, M.2    Lena, C.3    Bessis, A.4    Lallemand, Y.5    Le Novere, N.6
  • 52
    • 35648932901 scopus 로고    scopus 로고
    • Betaamyloid imaging and memory in non-demented individuals: Evidence for preclinical Alzheimer's disease
    • Pike KE, Savage G, Villemagne VL, Ng S, Moss SA, Maruff P, et al. Betaamyloid imaging and memory in non-demented individuals: evidence for preclinical Alzheimer's disease. Brain 2007; 130: 2837-44.
    • (2007) Brain , vol.130 , pp. 2837-2844
    • Pike, K.E.1    Savage, G.2    Villemagne, V.L.3    Ng, S.4    Moss, S.A.5    Maruff, P.6
  • 53
    • 0032953838 scopus 로고    scopus 로고
    • Acute effects of the selective cholinergic channel activator (nicotinic agonist) ABT-418 in Alzheimer's disease
    • Potter A, Corwin J, Lang J, Piasecki M, Lenox R, Newhouse PA. Acute effects of the selective cholinergic channel activator (nicotinic agonist) ABT-418 in Alzheimer's disease. Psychopharmacol 1999; 142: 334-42.
    • (1999) Psychopharmacol , vol.142 , pp. 334-342
    • Potter, A.1    Corwin, J.2    Lang, J.3    Piasecki, M.4    Lenox, R.5    Newhouse, P.A.6
  • 55
    • 0025803731 scopus 로고
    • A postmortem study of brain nicotinic receptors in Parkinson's and Alzheimer's disease
    • Rinne JO, Myllykyla T, Lonnberg P, Marjamaki P. A postmortem study of brain nicotinic receptors in Parkinson's and Alzheimer's disease. Brain Res 1991; 547: 167-70.
    • (1991) Brain Res , vol.547 , pp. 167-170
    • Rinne, J.O.1    Myllykyla, T.2    Lonnberg, P.3    Marjamaki, P.4
  • 56
    • 79959528866 scopus 로고    scopus 로고
    • Neuroscience. Attention-voluntary control of brain cells
    • Roelfsema PR. Neuroscience. Attention-voluntary control of brain cells. Science 2011; 332: 1512-3.
    • (2011) Science , vol.332 , pp. 1512-1513
    • Roelfsema, P.R.1
  • 58
    • 0036230041 scopus 로고    scopus 로고
    • The role of nicotinic receptor beta-2 subunits in nicotine discrimination and conditioned taste aversion
    • Shoaib M, Gommans J, Morley A, Stolerman IP, Grailhe R, Changeux JP. The role of nicotinic receptor beta-2 subunits in nicotine discrimination and conditioned taste aversion. Neuropharmacol 2002; 42: 530-9.
    • (2002) Neuropharmacol , vol.42 , pp. 530-539
    • Shoaib, M.1    Gommans, J.2    Morley, A.3    Stolerman, I.P.4    Grailhe, R.5    Changeux, J.P.6
  • 59
    • 67650875899 scopus 로고    scopus 로고
    • Amyloid deposition is associated with impaired default network function in older persons without dementia
    • Sperling RA, Laviolette PS, O'Keefe K, O'Brien J, Rentz DM, Pihlajamaki M, et al. Amyloid deposition is associated with impaired default network function in older persons without dementia. Neuron 2009; 63: 178-88.
    • (2009) Neuron , vol.63 , pp. 178-188
    • Sperling, R.A.1    Laviolette, P.S.2    O'keefe, K.3    O'brien, J.4    Rentz, D.M.5    Pihlajamaki, M.6
  • 60
    • 20444368757 scopus 로고    scopus 로고
    • Chronic nicotine exposure upregulates nicotinic receptors by a novel mechanism
    • Vallejo YF, Buisson B, Bertrand D, Green WN. Chronic nicotine exposure upregulates nicotinic receptors by a novel mechanism. J Neurosci 2005; 25: 5563-72.
    • (2005) J Neurosci , vol.25 , pp. 5563-5572
    • Vallejo, Y.F.1    Buisson, B.2    Bertrand, D.3    Green, W.N.4
  • 61
    • 84863198003 scopus 로고    scopus 로고
    • Regional dynamics of amyloid-beta deposition in healthy elderly, mild cognitive impairment and Alzheimer's disease: A voxelwise PiB-PET longitudinal study
    • Villain N, Chetelat G, Grassiot B, Bourgeat P, Jones G, Ellis KA, et al. Regional dynamics of amyloid-beta deposition in healthy elderly, mild cognitive impairment and Alzheimer's disease: a voxelwise PiB-PET longitudinal study. Brain 2012; 135: 2126-39.
    • (2012) Brain , vol.135 , pp. 2126-2139
    • Villain, N.1    Chetelat, G.2    Grassiot, B.3    Bourgeat, P.4    Jones, G.5    Ellis, K.A.6
  • 62
    • 0034006944 scopus 로고    scopus 로고
    • Beta-Amyloid(1-42) binds to alpha7 nicotinic acetylcholine receptor with high affinity. Implications for Alzheimer's disease pathology
    • Wang HY, Lee DH, D'Andrea MR, Peterson PA, Shank RP, Reitz AB. beta-Amyloid(1-42) binds to alpha7 nicotinic acetylcholine receptor with high affinity. Implications for Alzheimer's disease pathology. J Biol Chem 2000; 275: 5626-32.
    • (2000) J Biol Chem , vol.275 , pp. 5626-5632
    • Wang, H.Y.1    Lee, D.H.2    D'andrea, M.R.3    Peterson, P.A.4    Shank, R.P.5    Reitz, A.B.6
  • 63
    • 0029123862 scopus 로고
    • Nicotinic receptors and neurodegenerative dementing diseases: Basic research and clinical implications
    • Whitehouse PJ, Kalaria RN. Nicotinic receptors and neurodegenerative dementing diseases: basic research and clinical implications. Alzheimer Dis Assoc Disord 1995; 9 (Suppl 2): 3-5.
    • (1995) Alzheimer Dis Assoc Disord , vol.9 , Issue.SUPPL. 2 , pp. 3-5
    • Whitehouse, P.J.1    Kalaria, R.N.2
  • 64
    • 0024576043 scopus 로고
    • The pontomesencephalotegmental cholinergic system does not degenerate in Alzheimer's disease
    • Woolf NJ, Jacobs RW, Butcher LL. The pontomesencephalotegmental cholinergic system does not degenerate in Alzheimer's disease. Neurosci Lett 1989; 96: 277-82.
    • (1989) Neurosci Lett , vol.96 , pp. 277-282
    • Woolf, N.J.1    Jacobs, R.W.2    Butcher, L.L.3
  • 65
    • 4444222165 scopus 로고    scopus 로고
    • Lukas RJ. Beta-Amyloid directly inhibits human alpha4beta2-nicotinic acetylcholine receptors heterologously expressed in human SH-EP1 cells
    • Wu J, Kuo YP, George AA, Xu L, Hu J, Lukas RJ. beta-Amyloid directly inhibits human alpha4beta2-nicotinic acetylcholine receptors heterologously expressed in human SH-EP1 cells. J Biol Chem 2004; 279: 37842-51.
    • (2004) J Biol Chem , vol.279 , pp. 37842-37851
    • Wu, J.1    Kuo, Y.P.2    George, A.A.3    Xu, L.4    Hu, J.5
  • 66
    • 37549031240 scopus 로고    scopus 로고
    • Smoking upregulates alpha4beta2*nicotinic acetylcholine receptors in the human brain
    • Wullner U, Gundisch D, Herzog H, Minnerop M, Joe A, Warnecke M, et al. Smoking upregulates alpha4beta2*nicotinic acetylcholine receptors in the human brain. Neurosci Lett 2008; 430: 34-7.
    • (2008) Neurosci Lett , vol.430 , pp. 34-37
    • Wullner, U.1    Gundisch, D.2    Herzog, H.3    Minnerop, M.4    Joe, A.5    Warnecke, M.6
  • 67
    • 79551531674 scopus 로고    scopus 로고
    • In vivo changes in microglial activation and amyloid deposits in brain regions with hypometabolism in Alzheimer's disease
    • Yokokura M, Mori N, Yagi S, Yoshikawa E, Kikuchi M, Yoshihara Y, et al. In vivo changes in microglial activation and amyloid deposits in brain regions with hypometabolism in Alzheimer's disease. Eur J Nucl Med Mol Imaging 2011; 38: 343-51.
    • (2011) Eur J Nucl Med Mol Imaging , vol.38 , pp. 343-351
    • Yokokura, M.1    Mori, N.2    Yagi, S.3    Yoshikawa, E.4    Kikuchi, M.5    Yoshihara, Y.6
  • 68
    • 48949087468 scopus 로고    scopus 로고
    • Stereotaxic probabilistic maps of the magnocellular cell groups in human basal forebrain
    • Zaborszky L, Hoemke L, Mohlberg H, Schleicher A, Amunts K, Zilles K. Stereotaxic probabilistic maps of the magnocellular cell groups in human basal forebrain. Neuroimage 2008; 42: 1127-41.
    • (2008) Neuroimage , vol.42 , pp. 1127-1141
    • Zaborszky, L.1    Hoemke, L.2    Mohlberg, H.3    Schleicher, A.4    Amunts, K.5    Zilles, K.6
  • 69
    • 0033104499 scopus 로고    scopus 로고
    • Increased neurodegeneration during ageing in mice lacking high-affinity nicotine receptors
    • Zoli M, Picciotto MR, Ferrari R, Cocchi D, Changeux JP. Increased neurodegeneration during ageing in mice lacking high-affinity nicotine receptors. EMBO J 1999; 18: 1235-44.
    • (1999) EMBO J , vol.18 , pp. 1235-1244
    • Zoli, M.1    Picciotto, M.R.2    Ferrari, R.3    Cocchi, D.4    Changeux, J.P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.