Local pruning of dendrites and spines by caspase-3-dependent and proteasome-limited mechanisms

Journal of Neuroscience

Volumn 34, Issue 5, 2014, Pages 1672-1688

  Ertürk, Ali ^a   Wang, Yuanyuan ^a   Sheng, Morgan ^a  

^a GENENTECH INC   (United States)

Author keywords

Caspase 3; Dendrite retraction; IAP; Nonapoptotic; Proteasome; Spine elimination

Indexed keywords

CASPASE 3; PROTEASOME;

ADULT; ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN ELECTROPHYSIOLOGY; CELL STRUCTURE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DENDRITE; DENDRITIC SPINE; EMBRYO; EXCITATORY POSTSYNAPTIC POTENTIAL; HIPPOCAMPAL CA1 REGION; IMMUNOHISTOCHEMISTRY; MOUSE; NERVE CELL DEGENERATION; NERVE CELL NECROSIS; NONHUMAN; PHOTOSTIMULATION; PRIORITY JOURNAL; RAT; SPINE; TIME LAPSE IMAGING;

CASPASE-3; DENDRITE RETRACTION; IAP; NONAPOPTOTIC; PROTEASOME; SPINE ELIMINATION;

ACETYLCYSTEINE; AGE FACTORS; ANIMALS; CASPASE 3; CASPASE 9; CELLS, CULTURED; CYSTEINE PROTEINASE INHIBITORS; DENDRITES; DENDRITIC SPINES; EMBRYO, MAMMALIAN; ENZYME ACTIVATION; EXCITATORY POSTSYNAPTIC POTENTIALS; GENE EXPRESSION REGULATION; HIPPOCAMPUS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NEURONS; OLIGOPEPTIDES; PROTEASOME ENDOPEPTIDASE COMPLEX; RATS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; SYNAPSES; TIME FACTORS;

EID: 84893080766     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3121-13.2014     Document Type: Article

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