-
1
-
-
0026609559
-
Alternative excitotoxic hypotheses
-
Albin R. L., Greenamyre J. T. Alternative excitotoxic hypotheses. Neurology. 42:1992;733-738.
-
(1992)
Neurology
, vol.42
, pp. 733-738
-
-
Albin, R.L.1
Greenamyre, J.T.2
-
2
-
-
0025831751
-
Exact cleavage site of Alzheimer amyloid precursor in neuronal PC-12 cells
-
Anderson J. P., Esch F. S., Keim P. S., Sambamurti K., Lieberburg I., Robakis N. K. Exact cleavage site of Alzheimer amyloid precursor in neuronal PC-12 cells. Neurosci. Lett. 128:1991;126-128.
-
(1991)
Neurosci. Lett.
, vol.128
, pp. 126-128
-
-
Anderson, J.P.1
Esch, F.S.2
Keim, P.S.3
Sambamurti, K.4
Lieberburg, I.5
Robakis, N.K.6
-
3
-
-
14444267540
-
Characterization of new polyclonal antibodies specific for 40 and 42 amino acid-long amyloid beta peptides: Their use to examine the cell biology of presenilins and the immunohistochemistry of sporadic Alzheimer's disease and cerebral amyloid angiopathy cases
-
Barelli H., Lebeau A., Vizzavona J., Delaere P., Chevallier N., Drouot C., Marambaud P., Ancolio K., Buxbaum J. D., Khorkova O., Heroux J., Sahasrabudhe S., Martinez J., Warter J. M., Mohr M., Checler F. Characterization of new polyclonal antibodies specific for 40 and 42 amino acid-long amyloid beta peptides: Their use to examine the cell biology of presenilins and the immunohistochemistry of sporadic Alzheimer's disease and cerebral amyloid angiopathy cases. Mol. Med. 3:1997;695-707.
-
(1997)
Mol. Med.
, vol.3
, pp. 695-707
-
-
Barelli, H.1
Lebeau, A.2
Vizzavona, J.3
Delaere, P.4
Chevallier, N.5
Drouot, C.6
Marambaud, P.7
Ancolio, K.8
Buxbaum, J.D.9
Khorkova, O.10
Heroux, J.11
Sahasrabudhe, S.12
Martinez, J.13
Warter, J.M.14
Mohr, M.15
Checler, F.16
-
4
-
-
0029801982
-
Hereditary cerebral hemorrhage with amyloidosis-Dutch type (HCHWA-D): A review of clinical, radiologic and genetic aspects
-
Bornebroek M., Haan J., Maat-Schieman M. L., van Duinen S. G., Roos R. A. Hereditary cerebral hemorrhage with amyloidosis-Dutch type (HCHWA-D): A review of clinical, radiologic and genetic aspects. Nucl. Med. Commun. 17:1996;929-933.
-
(1996)
Nucl. Med. Commun.
, vol.17
, pp. 929-933
-
-
Bornebroek, M.1
Haan, J.2
Maat-Schieman, M.L.3
Van Duinen, S.G.4
Roos, R.A.5
-
5
-
-
0032558784
-
Neuron loss in APP transgenic mice
-
Calhoun M. E., Wiederhold K. H., Abramowski D., Phinney A. L., Probst A., Sturchler-Pierrat C., Staufenbiel M., Sommer B., Jucker M. Neuron loss in APP transgenic mice. Nature. 395:1998;755-756.
-
(1998)
Nature
, vol.395
, pp. 755-756
-
-
Calhoun, M.E.1
Wiederhold, K.H.2
Abramowski, D.3
Phinney, A.L.4
Probst, A.5
Sturchler-Pierrat, C.6
Staufenbiel, M.7
Sommer, B.8
Jucker, M.9
-
6
-
-
0029803744
-
Evidence that the 42- And 40-amino acid forms of amyloid beta protein are generated from the beta-amyloid precursor protein by different protease activities
-
Citron M., Diehl T. S., Gordon G., Biere A. L., Seubert P., Selkoe D. J. Evidence that the 42- and 40-amino acid forms of amyloid beta protein are generated from the beta-amyloid precursor protein by different protease activities. Proc. Natl. Acad. Sci. USA. 93:1996;13170-13175.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 13170-13175
-
-
Citron, M.1
Diehl, T.S.2
Gordon, G.3
Biere, A.L.4
Seubert, P.5
Selkoe, D.J.6
-
7
-
-
0027330265
-
Effects of the mutations Glu22 to Gln and Ala21 to Gly on the aggregation of a synthetic fragment of the Alzheimer's amyloid beta/A4 peptide
-
Clements A., Walsh D. M., Williams C. H., Allsop D. Effects of the mutations Glu22 to Gln and Ala21 to Gly on the aggregation of a synthetic fragment of the Alzheimer's amyloid beta/A4 peptide. Neurosci. Lett. 161:1993;17-20.
-
(1993)
Neurosci. Lett.
, vol.161
, pp. 17-20
-
-
Clements, A.1
Walsh, D.M.2
Williams, C.H.3
Allsop, D.4
-
9
-
-
0031690718
-
Presenile Alzheimer dementia characterized by amyloid angiopathy and large amyloid core type senile plaques in the APP 692Ala→Gly mutation
-
Cras P., van Harskamp F., Hendriks L., Ceuterick C., van Duijn C. M., Stefanko S. Z., Hofman A., Kros J. M., Van Broeckhoven C., Martin J. J. Presenile Alzheimer dementia characterized by amyloid angiopathy and large amyloid core type senile plaques in the APP 692Ala→Gly mutation. Acta Neuropathol. 96:1998;253-260.
-
(1998)
Acta Neuropathol.
, vol.96
, pp. 253-260
-
-
Cras, P.1
Van Harskamp, F.2
Hendriks, L.3
Ceuterick, C.4
Van Duijn, C.M.5
Stefanko, S.Z.6
Hofman, A.7
Kros, J.M.8
Van Broeckhoven, C.9
Martin, J.J.10
-
10
-
-
0031742418
-
Flemish and Dutch mutations in amyloid beta precursor protein have different effects on amyloid beta secretion
-
De Jonghe C., Zehr C., Yager D., Prada C. M., Younkin S., Hendriks L., Van Broeckhoven C., Eckman C. B. Flemish and Dutch mutations in amyloid beta precursor protein have different effects on amyloid beta secretion. Neurobiol. Dis. 5:1998;281-286.
-
(1998)
Neurobiol. Dis.
, vol.5
, pp. 281-286
-
-
De Jonghe, C.1
Zehr, C.2
Yager, D.3
Prada, C.M.4
Younkin, S.5
Hendriks, L.6
Van Broeckhoven, C.7
Eckman, C.B.8
-
11
-
-
0028892096
-
Production of intracellular amyloid-containing fragments in hippocampal neurons expressing human amyloid precursor protein and protection against amyloidogenesis by subtle amino acid substitutions in the rodent sequence
-
De Strooper B., Simons M., Multhaup G., Van Leuven F., Beyreuther K., Dotti C. G. Production of intracellular amyloid-containing fragments in hippocampal neurons expressing human amyloid precursor protein and protection against amyloidogenesis by subtle amino acid substitutions in the rodent sequence. EMBO J. 14:1995;4932-4938.
-
(1995)
EMBO J.
, vol.14
, pp. 4932-4938
-
-
De Strooper, B.1
Simons, M.2
Multhaup, G.3
Van Leuven, F.4
Beyreuther, K.5
Dotti, C.G.6
-
12
-
-
0030713963
-
Genetics of aging
-
Finch C. E., Tanzi R. E. Genetics of aging. Science. 278:1997;407-411.
-
(1997)
Science
, vol.278
, pp. 407-411
-
-
Finch, C.E.1
Tanzi, R.E.2
-
13
-
-
0028985574
-
Alzheimer-type neuropathology in transgenic mice overexpressing V717F beta-amyloid precursor protein
-
Games, D., Adams, D., Alessandrini, R., Barbour, R., Berthelette, P., Blackwell, C., Carr, T., Clemens, J., Donaldson, T., Gillespie, F., et al. 1995Alzheimer-type neuropathology in transgenic mice overexpressing V717F beta-amyloid precursor protein. Nature373, 523-527.
-
(1995)
Nature
, vol.373
, pp. 523-527
-
-
Games, D.1
Adams, D.2
Alessandrini, R.3
Barbour, R.4
Berthelette, P.5
Blackwell, C.6
Carr, T.7
Clemens, J.8
Donaldson, T.9
Gillespie, F.10
-
14
-
-
0026738851
-
Hippocampal excitatory amino acid receptors in elderly, normal individuals and those with Alzheimer's disease: Non-N-methyl-d-aspartate receptors
-
Geddes J. W., Ulas J., Brunner L. C., Choe W., Cotman C. W. Hippocampal excitatory amino acid receptors in elderly, normal individuals and those with Alzheimer's disease: Non-N-methyl-d-aspartate receptors. Neuroscience. 50:1992;23-34.
-
(1992)
Neuroscience
, vol.50
, pp. 23-34
-
-
Geddes, J.W.1
Ulas, J.2
Brunner, L.C.3
Choe, W.4
Cotman, C.W.5
-
15
-
-
0026088977
-
Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease
-
Goate, A., Chartier, H. M., Mullan, M., Brown, J., Crawford, F., Fidani, L., Giuffra, L., Haynes, A., Irving, N., James, L., et al.1991Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease. Nature349, 704-706.
-
(1991)
Nature
, vol.349
, pp. 704-706
-
-
Goate, A.1
Chartier, H.M.2
Mullan, M.3
Brown, J.4
Crawford, F.5
Fidani, L.6
Giuffra, L.7
Haynes, A.8
Irving, N.9
James, L.10
-
17
-
-
0024363934
-
Excitatory amino acids and Alzheimer's disease
-
Greenamyre J. T., Young A. B. Excitatory amino acids and Alzheimer's disease. Neurobiol. Aging. 10:1989;593-602.
-
(1989)
Neurobiol. Aging
, vol.10
, pp. 593-602
-
-
Greenamyre, J.T.1
Young, A.B.2
-
18
-
-
0028246308
-
Mutations associated with a locus for familial Alzheimer's disease result in alternative processing of amyloid beta-protein precursor
-
Haass C., Hung A. Y., Selkoe D. J., Teplow D. B. Mutations associated with a locus for familial Alzheimer's disease result in alternative processing of amyloid beta-protein precursor. J. Biol. Chem. 269:1994;17741-17748.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 17741-17748
-
-
Haass, C.1
Hung, A.Y.2
Selkoe, D.J.3
Teplow, D.B.4
-
19
-
-
0026646604
-
Amyloid beta-peptide is produced by cultured cells during normal metabolism
-
Haass C., Schlossmacher M. G., Hung A. Y., Vigo-Pelfrey C., Mellon A., Ostaszewski B. L., Lieberburg I., Koo E. H., Schenk D., Teplow D. B. Amyloid beta-peptide is produced by cultured cells during normal metabolism. Nature. 359:1992;322-325.
-
(1992)
Nature
, vol.359
, pp. 322-325
-
-
Haass, C.1
Schlossmacher, M.G.2
Hung, A.Y.3
Vigo-Pelfrey, C.4
Mellon, A.5
Ostaszewski, B.L.6
Lieberburg, I.7
Koo, E.H.8
Schenk, D.9
Teplow, D.B.10
-
20
-
-
0343570974
-
Alzheimer's disease and hemorrhagic stroke: Their relationship to beta amyloid deposition
-
K. S. Kosik. Berlin/Heidelberg: Springer-Verlag
-
Hendriks L., Cras P., Martin J. J., Van Broeckhoven C. Alzheimer's disease and hemorrhagic stroke: Their relationship to beta amyloid deposition. Kosik K. S. Alzheimer's Disease: Lessons from Cell Biology. 1995;37-48 Springer-Verlag, Berlin/Heidelberg.
-
(1995)
Alzheimer's Disease: Lessons from Cell Biology
, pp. 37-48
-
-
Hendriks, L.1
Cras, P.2
Martin, J.J.3
Van Broeckhoven, C.4
-
21
-
-
0026879650
-
Presenile dementia and cerebral haemorrhage linked to a mutation at codon 692 of the beta-amyloid precursor protein gene
-
Hendriks L., van Duijn C. M., Cras P., Cruts M., van Harskamp F., Warren A., McInnis M. G., Antonarakis S. E., Martin J. J., Van Broeckhoven C. Presenile dementia and cerebral haemorrhage linked to a mutation at codon 692 of the beta-amyloid precursor protein gene. Nat. Genet. 1:1992;218-221.
-
(1992)
Nat. Genet.
, vol.1
, pp. 218-221
-
-
Hendriks, L.1
Van Duijn, C.M.2
Cras, P.3
Cruts, M.4
Van Harskamp, F.5
Warren, A.6
McInnis, M.G.7
Antonarakis, S.E.8
Martin, J.J.9
Van Broeckhoven, C.10
-
22
-
-
0028232799
-
Transgenic mouse brain histopathology resembles early Alzheimer's disease
-
Higgins L. S., Holtzman D. M., Rabin J., Mobley W. C., Cordell B. Transgenic mouse brain histopathology resembles early Alzheimer's disease. Ann. Neurol. 35:1994;598-607.
-
(1994)
Ann. Neurol.
, vol.35
, pp. 598-607
-
-
Higgins, L.S.1
Holtzman, D.M.2
Rabin, J.3
Mobley, W.C.4
Cordell, B.5
-
24
-
-
0032928653
-
Natural history of behavioural changes and psychiatric symptoms in Alzheimer's disease. A longitudinal study
-
Hope T., Keene J., Fairburn C. G., Jacoby R., McShane R. Natural history of behavioural changes and psychiatric symptoms in Alzheimer's disease. A longitudinal study. Br. J. Psychiatry. 174:1999;39-44.
-
(1999)
Br. J. Psychiatry
, vol.174
, pp. 39-44
-
-
Hope, T.1
Keene, J.2
Fairburn, C.G.3
Jacoby, R.4
McShane, R.5
-
25
-
-
0029159875
-
Mutant and native human beta-amyloid precursor proteins in transgenic mouse brain
-
Howland D. S., Savage M. J., Huntress F. A., Wallace R. E., Schwartz D. A., Loh T., Melloni R. H. J., DeGennaro L. J., Greenberg B. D., Siman R. Mutant and native human beta-amyloid precursor proteins in transgenic mouse brain. Neurobiol. Aging. 16:1995;685-699.
-
(1995)
Neurobiol. Aging
, vol.16
, pp. 685-699
-
-
Howland, D.S.1
Savage, M.J.2
Huntress, F.A.3
Wallace, R.E.4
Schwartz, D.A.5
Loh, T.6
Melloni, R.H.J.7
Degennaro, L.J.8
Greenberg, B.D.9
Siman, R.10
-
26
-
-
13044287361
-
Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models
-
Hsia A. Y., Masliah E., McConlogue L., Yu G. Q., Tatsuno G., Hu K., Kholodenko D., Malenka R. C., Nicoll R. A., Mucke L. Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models. Proc. Natl. Acad. Sci. USA. 96:1999;3228-3233.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 3228-3233
-
-
Hsia, A.Y.1
Masliah, E.2
McConlogue, L.3
Yu, G.Q.4
Tatsuno, G.5
Hu, K.6
Kholodenko, D.7
Malenka, R.C.8
Nicoll, R.A.9
Mucke, L.10
-
27
-
-
0029742199
-
Correlative memory deficits, A beta elevation, and amyloid plaques in transgenic mice
-
Hsiao K., Chapman P., Nilsen S., Eckman C., Harigaya Y., Younkin S., Yang F., Cole G. Correlative memory deficits, A beta elevation, and amyloid plaques in transgenic mice. Science. 274:1996;99-102.
-
(1996)
Science
, vol.274
, pp. 99-102
-
-
Hsiao, K.1
Chapman, P.2
Nilsen, S.3
Eckman, C.4
Harigaya, Y.5
Younkin, S.6
Yang, F.7
Cole, G.8
-
28
-
-
0028810244
-
Age-related CNS disorder and early death in transgenic FVB/N mice overexpressing Alzheimer amyloid precursor proteins
-
Hsiao K. K., Borchelt D. R., Olson K., Johannsdottir R., Kitt C., Yunis W., Xu S., Eckman C., Younkin S., Price D. Age-related CNS disorder and early death in transgenic FVB/N mice overexpressing Alzheimer amyloid precursor proteins. Neuron. 15:1995;1203-1218.
-
(1995)
Neuron
, vol.15
, pp. 1203-1218
-
-
Hsiao, K.K.1
Borchelt, D.R.2
Olson, K.3
Johannsdottir, R.4
Kitt, C.5
Yunis, W.6
Xu, S.7
Eckman, C.8
Younkin, S.9
Price, D.10
-
29
-
-
0025687708
-
Alzheimer's disease: Changes in hippocampal N-methyl-d-aspartate, quisqualate, neurotensin, adenosine, benzodiazepine, serotonin and opioid receptors - An autoradiographic study
-
Jansen K. L., Faull R. L., Dragunow M., Synek B. L. Alzheimer's disease: Changes in hippocampal N-methyl-d-aspartate, quisqualate, neurotensin, adenosine, benzodiazepine, serotonin and opioid receptors - An autoradiographic study. Neuroscience. 39:1990;613-627.
-
(1990)
Neuroscience
, vol.39
, pp. 613-627
-
-
Jansen, K.L.1
Faull, R.L.2
Dragunow, M.3
Synek, B.L.4
-
30
-
-
0027195933
-
Seeding "one-dimensional crystallization" of amyloid: A pathogenic mechanism in Alzheimer's disease and scrapie?
-
Jarrett J. T., Lansbury-PT J. Seeding "one-dimensional crystallization" of amyloid: A pathogenic mechanism in Alzheimer's disease and scrapie? Cell. 73:1993;1055-1058.
-
(1993)
Cell
, vol.73
, pp. 1055-1058
-
-
Jarrett, J.T.1
Lansbury-Pt, J.2
-
31
-
-
0027477716
-
Familial Alzheimer's disease. A pedigree with a mis-sense mutation in the amyloid precursor protein gene (amyloid precursor protein 717 valine→glycine)
-
Kennedy A. M., Newman S., McCaddon A., Ball J., Roques P., Mullan M., Hardy J., Chartier-Harlin M. C., Frackowiak R. S., Warrington E. K. Familial Alzheimer's disease. A pedigree with a mis-sense mutation in the amyloid precursor protein gene (amyloid precursor protein 717 valine→glycine). Brain. 116:1993;309-324.
-
(1993)
Brain
, vol.116
, pp. 309-324
-
-
Kennedy, A.M.1
Newman, S.2
McCaddon, A.3
Ball, J.4
Roques, P.5
Mullan, M.6
Hardy, J.7
Chartier-Harlin, M.C.8
Frackowiak, R.S.9
Warrington, E.K.10
-
32
-
-
0025110182
-
Beta-amyloid protein increases the vulnerability of cultured cortical neurons to excitotoxic damage
-
Koh J. Y., Yang L. L., Cotman C. W. Beta-amyloid protein increases the vulnerability of cultured cortical neurons to excitotoxic damage. Brain Res. 533:1990;315-320.
-
(1990)
Brain Res.
, vol.533
, pp. 315-320
-
-
Koh, J.Y.1
Yang, L.L.2
Cotman, C.W.3
-
33
-
-
0028981717
-
The Alzheimer's A beta peptide induces neurodegeneration and apoptotic cell death in transgenic mice
-
LaFerla F. M., Tinkle B. T., Bieberich C. J., Haudenschild C. C., Jay G. The Alzheimer's A beta peptide induces neurodegeneration and apoptotic cell death in transgenic mice. Nat. Genet. 9:1995;21-30.
-
(1995)
Nat. Genet.
, vol.9
, pp. 21-30
-
-
Laferla, F.M.1
Tinkle, B.T.2
Bieberich, C.J.3
Haudenschild, C.C.4
Jay, G.5
-
34
-
-
0027971051
-
Phenotype of chromosome 14-linked familial Alzheimer's disease in a large kindred
-
Lampe T. H., Bird T. D., Nochlin D., Nemens E., Risse S. C., Sumi S. M., Koerker R., Leaird B., Wier M., Raskind M. A. Phenotype of chromosome 14-linked familial Alzheimer's disease in a large kindred. Ann. Neurol. 36:1994;368-378.
-
(1994)
Ann. Neurol.
, vol.36
, pp. 368-378
-
-
Lampe, T.H.1
Bird, T.D.2
Nochlin, D.3
Nemens, E.4
Risse, S.C.5
Sumi, S.M.6
Koerker, R.7
Leaird, B.8
Wier, M.9
Raskind, M.A.10
-
35
-
-
0025296269
-
Mutation of the Alzheimer's disease amyloid gene in hereditary cerebral hemorrhage, Dutch type
-
Levy E., Carman M. D., Fernandez-Madrid I. J., Power M. D., Lieberburg I., van Duinen S. G., Bots G. T., Luyendijk W., Frangione B. Mutation of the Alzheimer's disease amyloid gene in hereditary cerebral hemorrhage, Dutch type. Science. 248:1990;1124-1126.
-
(1990)
Science
, vol.248
, pp. 1124-1126
-
-
Levy, E.1
Carman, M.D.2
Fernandez-Madrid, I.J.3
Power, M.D.4
Lieberburg, I.5
Van Duinen, S.G.6
Bots, G.T.7
Luyendijk, W.8
Frangione, B.9
-
36
-
-
0025959458
-
Early-onset Alzheimer's disease in 2 large Belgian families
-
Martin J. J., Gheuens J., Bruyland M., Cras P., Vandenberghe A., Masters C. L., Beyreuther K., Dom R., Ceuterick C., Lubke U. Early-onset Alzheimer's disease in 2 large Belgian families. Neurology. 41:1991;62-68.
-
(1991)
Neurology
, vol.41
, pp. 62-68
-
-
Martin, J.J.1
Gheuens, J.2
Bruyland, M.3
Cras, P.4
Vandenberghe, A.5
Masters, C.L.6
Beyreuther, K.7
Dom, R.8
Ceuterick, C.9
Lubke, U.10
-
37
-
-
0027941257
-
Synaptic plasticity in the hippocampus: LTP and LTD
-
Malenka R. C. Synaptic plasticity in the hippocampus: LTP and LTD. Cell. 78:1994;535-538.
-
(1994)
Cell
, vol.78
, pp. 535-538
-
-
Malenka, R.C.1
-
38
-
-
0032524290
-
Amyloid protein precursor stimulates excitatory amino acid transport. Implications for roles in neuroprotection and pathogenesis
-
Masliah E., Raber J., Alford M., Mallory M., Mattson M. P., Yang D., Wong D., Mucke L. Amyloid protein precursor stimulates excitatory amino acid transport. Implications for roles in neuroprotection and pathogenesis. J. Biol. Chem. 273:1998;12548-12554.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 12548-12554
-
-
Masliah, E.1
Raber, J.2
Alford, M.3
Mallory, M.4
Mattson, M.P.5
Yang, D.6
Wong, D.7
Mucke, L.8
-
39
-
-
0030867815
-
Neuronal expression of beta-amyloid precursor protein Alzheimer mutations causes intracellular accumulation of a C-terminal fragment containing both the beta-amyloid and cytoplasmic domains
-
Mc Phie D., Lee R., Eckman C., Olstein D., Durham S., Yager D., Younkin S., Wurtman R., Neve R. Neuronal expression of beta-amyloid precursor protein Alzheimer mutations causes intracellular accumulation of a C-terminal fragment containing both the beta-amyloid and cytoplasmic domains. J. Biol. Chem. 272:1997;24743-24746.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 24743-24746
-
-
Mc Phie, D.1
Lee, R.2
Eckman, C.3
Olstein, D.4
Durham, S.5
Yager, D.6
Younkin, S.7
Wurtman, R.8
Neve, R.9
-
40
-
-
0029917041
-
Expression in brain of amyloid precursor protein mutated in the alpha-secretase site causes disturbed behavior, neuronal degeneration and premature death in transgenic mice
-
Moechars D., Lorent K., De Strooper B., Dewachter I., Van Leuven F. Expression in brain of amyloid precursor protein mutated in the alpha-secretase site causes disturbed behavior, neuronal degeneration and premature death in transgenic mice. EMBO J. 15:1996;1265-1274.
-
(1996)
EMBO J.
, vol.15
, pp. 1265-1274
-
-
Moechars, D.1
Lorent, K.2
De Strooper, B.3
Dewachter, I.4
Van Leuven, F.5
-
41
-
-
0032538959
-
Aggressive behaviour in transgenic mice expressing APP is alleviated by serotonergic drugs
-
Moechars D., Gilis M., Kuiperi C., Laenen I., Van Leuven F. Aggressive behaviour in transgenic mice expressing APP is alleviated by serotonergic drugs. NeuroReport. 16:1998a;3561-3564.
-
(1998)
NeuroReport
, vol.16
, pp. 3561-3564
-
-
Moechars, D.1
Gilis, M.2
Kuiperi, C.3
Laenen, I.4
Van Leuven, F.5
-
42
-
-
0032167860
-
Transgenic mice expressing an alpha-secretion mutant of the amyloid precursor protein in the brain develop a progressive CNS disorder
-
Moechars D., Lorent K., Dewachter I., Baekelandt V., De Strooper B., Van Leuven F. Transgenic mice expressing an alpha-secretion mutant of the amyloid precursor protein in the brain develop a progressive CNS disorder. Behav. Brain Res. 95:1998b;55-64.
-
(1998)
Behav. Brain Res.
, vol.95
, pp. 55-64
-
-
Moechars, D.1
Lorent, K.2
Dewachter, I.3
Baekelandt, V.4
De Strooper, B.5
Van Leuven, F.6
-
43
-
-
0033525520
-
Early phenotypic changes in transgenic mice that overexpress different mutants of amyloid precursor protein in brain
-
Moechars D., Dewachter I., Lorent K., Reverse D., Baekelandt V., Naidu A., Tesseur I., Spittaels K., Van Den Haute C., Cordell B., Checler F., Godaux E., Van Leuven F. Early phenotypic changes in transgenic mice that overexpress different mutants of amyloid precursor protein in brain. J. Biol. Chem. 10:1999a;6483-6492.
-
(1999)
J. Biol. Chem.
, vol.10
, pp. 6483-6492
-
-
Moechars, D.1
Dewachter, I.2
Lorent, K.3
Reverse, D.4
Baekelandt, V.5
Naidu, A.6
Tesseur, I.7
Spittaels, K.8
Van Den Haute, C.9
Cordell, B.10
Checler, F.11
Godaux, E.12
Van Leuven, F.13
-
44
-
-
0032953541
-
Premature death in transgenic mice that overexpress a mutant amyloid precursor protein is preceded by severe neurodegeneration and apoptosis
-
Moechars D., Lorent K., Van Leuven F. Premature death in transgenic mice that overexpress a mutant amyloid precursor protein is preceded by severe neurodegeneration and apoptosis. Neuroscience. 91:1999b;819-830.
-
(1999)
Neuroscience
, vol.91
, pp. 819-830
-
-
Moechars, D.1
Lorent, K.2
Van Leuven, F.3
-
45
-
-
0029055738
-
Age-related learning deficits in transgenic mice expressing the 751-amino acid isoform of human beta-amyloid precursor protein
-
Moran P. M., Higgins L. S., Cordell B., Moser P. C. Age-related learning deficits in transgenic mice expressing the 751-amino acid isoform of human beta-amyloid precursor protein. Proc. Natl. Acad. Sci. USA. 92:1995;5341-5345.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 5341-5345
-
-
Moran, P.M.1
Higgins, L.S.2
Cordell, B.3
Moser, P.C.4
-
46
-
-
0026907151
-
A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of beta-amyloid
-
Mullan M., Crawford F., Axelman K., Houlden H., Lilius L., Winblad B., Lannfelt L. A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of beta-amyloid. Nat. Genet. 1:1992;345-347.
-
(1992)
Nat. Genet.
, vol.1
, pp. 345-347
-
-
Mullan, M.1
Crawford, F.2
Axelman, K.3
Houlden, H.4
Lilius, L.5
Winblad, B.6
Lannfelt, L.7
-
47
-
-
0027219223
-
Clinical comparison of Alzheimer's disease in pedigrees with the codon 717 Val→Ile mutation in the amyloid precursor protein gene
-
Mullan M., Tsuji S., Miki T., Katsuya T., Naruse S., Kaneko K., Shimizu T., Kojima T., Nakano I., Ogihara T. Clinical comparison of Alzheimer's disease in pedigrees with the codon 717 Val→Ile mutation in the amyloid precursor protein gene. Neurobiol. Aging. 14:1993;407-419.
-
(1993)
Neurobiol. Aging
, vol.14
, pp. 407-419
-
-
Mullan, M.1
Tsuji, S.2
Miki, T.3
Katsuya, T.4
Naruse, S.5
Kaneko, K.6
Shimizu, T.7
Kojima, T.8
Nakano, I.9
Ogihara, T.10
-
48
-
-
0028243033
-
Cellular and molecular biology of Alzheimer's disease and animal models
-
Price D. L., Sisodia S. S. Cellular and molecular biology of Alzheimer's disease and animal models. Annu. Rev. Med. 45:1994;435-446.
-
(1994)
Annu. Rev. Med.
, vol.45
, pp. 435-446
-
-
Price, D.L.1
Sisodia, S.S.2
-
49
-
-
0025743350
-
Formation of beta-amyloid protein deposits in brains of transgenic mice
-
Quon D., Wang Y., Catalano R., Scardina J. M., Murakami K., Cordell B. Formation of beta-amyloid protein deposits in brains of transgenic mice. Nature. 352:1991;239-241.
-
(1991)
Nature
, vol.352
, pp. 239-241
-
-
Quon, D.1
Wang, Y.2
Catalano, R.3
Scardina, J.M.4
Murakami, K.5
Cordell, B.6
-
50
-
-
0024996068
-
Advanced Alzheimer's disease is a risk factor for late-onset seizures
-
Romanelli M. F., Morris J. C., Ashkin K., Coben L. A. Advanced Alzheimer's disease is a risk factor for late-onset seizures. Arch. Neurol. 47:1990;847-850.
-
(1990)
Arch. Neurol.
, vol.47
, pp. 847-850
-
-
Romanelli, M.F.1
Morris, J.C.2
Ashkin, K.3
Coben, L.A.4
-
51
-
-
0026378765
-
Hereditary cerebral hemorrhage with amyloidosis-Dutch type: A congophilic angiopathy. An overview
-
Roos R. A., Haan J., Van Broeckhoven C. Hereditary cerebral hemorrhage with amyloidosis-Dutch type: A congophilic angiopathy. An overview. Ann. N. Y. Acad. Sci. 640:1991;155-160.
-
(1991)
Ann. N. Y. Acad. Sci.
, vol.640
, pp. 155-160
-
-
Roos, R.A.1
Haan, J.2
Van Broeckhoven, C.3
-
52
-
-
0028872674
-
Excitotoxicity and the NMDA receptor - Still lethal after eight years
-
Rothman S. M., Olney J. W. Excitotoxicity and the NMDA receptor - Still lethal after eight years. Trends Neurosci. 18:1995;57-58.
-
(1995)
Trends Neurosci.
, vol.18
, pp. 57-58
-
-
Rothman, S.M.1
Olney, J.W.2
-
53
-
-
0028267440
-
Normal and abnormal biology of the beta-amyloid precursor protein
-
Selkoe D. J. Normal and abnormal biology of the beta-amyloid precursor protein. Annu. Rev. Neurosci. 17:1994;489-517.
-
(1994)
Annu. Rev. Neurosci.
, vol.17
, pp. 489-517
-
-
Selkoe, D.J.1
-
54
-
-
0029068857
-
Cortical petechial hemorrhage, leukoencephalopathy, and subacute dementia associated with seizures due to cerebral amyloid angiopathy
-
Silbert P. L., Bartleson J. D., Miller G. M., Parisi J. E., Goldman M. S., Meyer F. B. Cortical petechial hemorrhage, leukoencephalopathy, and subacute dementia associated with seizures due to cerebral amyloid angiopathy. Mayo Clin. Proc. 70:1995;477-480.
-
(1995)
Mayo Clin. Proc.
, vol.70
, pp. 477-480
-
-
Silbert, P.L.1
Bartleson, J.D.2
Miller, G.M.3
Parisi, J.E.4
Goldman, M.S.5
Meyer, F.B.6
-
55
-
-
0030915187
-
Functional screening of 2 Mb of human chromosome 21q22.2 in transgenic mice implicates minibrain in learning defects associated with Down syndrome
-
Smith D. J., Stevens M. E., Sudanagunta S. P., Bronson R. T., Makhinson M., Watabe A. M., O'Dell T. J., Fung J., Weier H. U., Cheng J. F., Rubin E. M. Functional screening of 2 Mb of human chromosome 21q22.2 in transgenic mice implicates minibrain in learning defects associated with Down syndrome. Nat. Genet. 16:1997;28-36.
-
(1997)
Nat. Genet.
, vol.16
, pp. 28-36
-
-
Smith, D.J.1
Stevens, M.E.2
Sudanagunta, S.P.3
Bronson, R.T.4
Makhinson, M.5
Watabe, A.M.6
O'Dell, T.J.7
Fung, J.8
Weier, H.U.9
Cheng, J.F.10
Rubin, E.M.11
-
56
-
-
0033007282
-
Behavioural problems associated with dementia: The role of newer antipsychotics
-
Stoppe G., Brandt C. A., Staedt J. H. Behavioural problems associated with dementia: The role of newer antipsychotics. Drugs Aging. 14:1999;41-54.
-
(1999)
Drugs Aging
, vol.14
, pp. 41-54
-
-
Stoppe, G.1
Brandt, C.A.2
Staedt, J.H.3
-
57
-
-
0011444914
-
Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology
-
Sturchler-Pierrat C., Abramowski D., Duke M., Wiederhold K. H., Mistl C., Rothacher S., Ledermann B., Burki K., Frey P., Paganetti P. A., Waridel C., Calhoun M. E., Jucker M., Probst A., Staufenbiel M., Sommer B. Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology. Proc. Natl. Acad. Sci. USA. 94:1997;13287-13292.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 13287-13292
-
-
Sturchler-Pierrat, C.1
Abramowski, D.2
Duke, M.3
Wiederhold, K.H.4
Mistl, C.5
Rothacher, S.6
Ledermann, B.7
Burki, K.8
Frey, P.9
Paganetti, P.A.10
Waridel, C.11
Calhoun, M.E.12
Jucker, M.13
Probst, A.14
Staufenbiel, M.15
Sommer, B.16
-
58
-
-
0028109531
-
Genes in early onset Alzheimer's disease: Implications for AD research
-
Van Broeckhoven C. Genes in early onset Alzheimer's disease: Implications for AD research. Neurobiol. Aging. 15:1994;S149-S153.
-
(1994)
Neurobiol. Aging
, vol.15
-
-
Van Broeckhoven, C.1
-
59
-
-
0025369198
-
Amyloid beta protein precursor gene and hereditary cerebral hemorrhage with amyloidosis (Dutch)
-
Van Broeckhoven C., Haan J., Bakker E., Hardy J. A., Van Hul W., Wehnert A., Vegter-Van D. V., Roos R. A. Amyloid beta protein precursor gene and hereditary cerebral hemorrhage with amyloidosis (Dutch). Science. 248:1990;1120-1122.
-
(1990)
Science
, vol.248
, pp. 1120-1122
-
-
Van Broeckhoven, C.1
Haan, J.2
Bakker, E.3
Hardy, J.A.4
Van Hul, W.5
Wehnert, A.6
Vegter-Van, D.V.7
Roos, R.A.8
-
60
-
-
0028026997
-
Apolipoprotein E4 allele in a population-based study of early-onset Alzheimer's disease
-
van Duijn C. M., de Knijff P., Cruts M., Wehnert A., Havekes L. M., Hofman A., Van Broeckhoven C. Apolipoprotein E4 allele in a population-based study of early-onset Alzheimer's disease. Nat. Genet. 7:1994;74-78.
-
(1994)
Nat. Genet.
, vol.7
, pp. 74-78
-
-
Van Duijn, C.M.1
De Knijff, P.2
Cruts, M.3
Wehnert, A.4
Havekes, L.M.5
Hofman, A.6
Van Broeckhoven, C.7
-
61
-
-
0344193422
-
-
K. Iqbal, B. Winblad, M. Nishimura, M. Takeda, & H. Wisniewski. New York: Wiley
-
van Harskamp F., Cras P., Hendriks L., Kros J. M., Martin J. J., Hofman A., Van Broeckhoven C., van Duijn C. M. Iqbal K., Winblad B., Nishimura M., Takeda M., Wisniewski H. Alzheimer's Disease: Biology, Diagnostics and Therapeutics. 1999;155-159 Wiley, New York.
-
(1999)
Alzheimer's Disease: Biology, Diagnostics and Therapeutics
, pp. 155-159
-
-
Van Harskamp, F.1
Cras, P.2
Hendriks, L.3
Kros, J.M.4
Martin, J.J.5
Hofman, A.6
Van Broeckhoven, C.7
Van Duijn, C.M.8
-
62
-
-
0030779705
-
Animal models of cerebral beta-amyloid angiopathy
-
Walker L. C. Animal models of cerebral beta-amyloid angiopathy. Brain Res. Brain Res. Rev. 25:1997;70-84.
-
(1997)
Brain Res. Brain Res. Rev.
, vol.25
, pp. 70-84
-
-
Walker, L.C.1
-
63
-
-
0025720097
-
Peptides homologous to the amyloid protein of Alzheimer's disease containing a glutamine for glutamic acid substitution have accelerated amyloid fibril formation
-
Wisniewski T., Ghiso J., Frangione B. Peptides homologous to the amyloid protein of Alzheimer's disease containing a glutamine for glutamic acid substitution have accelerated amyloid fibril formation. Biochem. Biophys. Res. Commun. 180:1991;1528.
-
(1991)
Biochem. Biophys. Res. Commun.
, vol.180
, pp. 1528
-
-
Wisniewski, T.1
Ghiso, J.2
Frangione, B.3
|