Neuronal cytoskeletal changes are an early consequence of repetitive head injury

Acta Neuropathologica

Volumn 98, Issue 2, 1999, Pages 171-178

  Geddes, J F ^a   Vowles, G H ^a   Nicoll, J A R ^b   Revesz T ^c  

^a ST BARTHOLOMEW S HOSPITAL   (United Kingdom)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Chronic traumatic brain injury; Dementia pugilistica; Head injury; Hyperphosphorylation of tau; Neurofiblillary tangles

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; APOLIPOPROTEIN E; TAU PROTEIN;

ADULT; ARTICLE; AUTOPSY; BLOOD VESSEL; BOXING; BRAIN INJURY; BRAIN SLICE; CLINICAL ARTICLE; CYTOSKELETON; DEMENTIA; EPILEPSY; FOOTBALL; FRONTAL LOBE; GENOTYPE; HEAD INJURY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LOBECTOMY; MALE; MENTAL DEFICIENCY; NEOCORTEX; NERVE CELL LESION; NEUROFIBRILLARY TANGLE; NEUROPATHOLOGY; NEUROPIL THREAD; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECURRENT DISEASE;

EID: 0032868750     PISSN: 00016322     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004010051066     Document Type: Article

References (63)

1. Aotsuka A, Kojima S, Furumoto H, Hattori T, Hirayama K (1990) [Punch drunk syndrome due to repeated karate kicks and punches]. Rinsho Shinkeigaku 30: 1243-1246
2. Blumbergs PC, Scott G. Manavis J, Wainwright H, Simpson DA, McLean AJ (1994) Staining of amyloid precursor protein to study axonal damage in mild head injury. Lancet 344: 1055-1056
3. Blumbergs PC, Scott G, Manavis J, Wainwright H, Simpson DA, McLean AJ (1995) Topography of axonal injury as defined by amyloid precursor protein and the sector scoring method in mild and severe closed head injury. J Neurotrauma 12:565-572
4. Braak E, Braak H, Mandelkow E (1994) A sequence of cytoskeleton changes related to the formation of neurofibrillary tangles and neuropil threads. Acta Neuropathol 87:554-567
5. Braak H, Braak E (1991) Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol 82:239-259
6. Buee-Scherrer V, Buee L, Hof PR, Leveugle B, Gilles C, Loerzel AJ, Perl DP, Delacourte A (1995) Neurofibrillary degeneration in amyotrophic lateral sclerosis/parkinsonism-dementia complex of Guam. Immunochemical characterization of tau proteins. Am J Pathol 146:924-932
7. Buee-Scherrer V, Buee L, Leveugle B, Perl DP, Vermersch P, Hof PR, Delacourte A (1997) Pathological tau proteins in postencephalitic parkinsonism: comparison with Alzheimer's disease and other neurodegenerative disorders. Ann Neurol 42: 356-359
8. Cairns NJ, Atkinson PF, Hanger DP, Anderton BH, Daniel SE, Lantos PL (1997) Tau protein in the glial cytoplasmic inclusions of multiple system atrophy can be distinguished from abnormal tau in Alzheimer's disease. Neurosci Lett 230:49-52
9. Casson IR, Siegel O, Sham R, Campbell EA, Tarlau M, DiDomenico A (1984) Brain damage in modern boxers. JAMA 251:2663-2667
10. Corsellis J, Bruton C, Freeman-Browne D (1973) The aftermath of boxing. Psychol Med 3:270-303
11. Dale GE, Leigh PN, Luthert P, Anderton BH, Roberts GW (1991) Neurofibrillary tangles in dementia pugilistica are ubiquitinated. J Neurol Neurosurg Psychiatry 54: 116-118
12. Delacourte A, Buee L (1997) Normal and pathological tau proteins as factors for microtubule assembly. Int Rev Cytol 171: 167-221
13. Dewar D, Graham DI, Teasdale GM, McCulloch J (1994) Cerebral ischemia induces alterations in tau and ubiquitin proteins. Dementia 5:168-173
14. Editorial (1976) Brain damage in sport. Lancet I: 401-402
15. Elliott EM, Mattson MP, Vanderklish P, Lynch G, Chang I, Sapolsky RM (1993) Corticosterone exacerbates kainate-induced alterations in hippocampal tau immunoreactivity and spectrin proteolysis in vivo. J Neurochem 61 :57-67
16. Ellis EF, McKinney JS, Willoughby KA, Liang S, Povlishock JT (1995) A new model for rapid stretch-induced injury of cells in culture: characterization of the model using astrocytes. J Neurotrauma 12:325-339
17. Geddes JF, Vowles GH, Robinson SFD, Sutcliffe JS (1996) Neurofibrillary tangles, not Alzheimer-type pathology, in a young boxer. Neuropathol Appl Neurobiol 22:12-16
18. Geddes JW, Schwab C, Craddock S, Wilson JL, Pettigrew LC (1994) Alterations in tau immunostaining in the rat hippocampus following transient cerebral ischemia. J Cereb Blood Flow Metab 14:554-564
19. Gennarelli TA, Thibault LE, Tipperman R, Tomei G, Sergot R, Brown M, Maxwell WL, Graham DI, Adams JH, Irvine A, et al (1989) Axonal injury in the optic nerve: a model simulating diffuse axonal injury in the brain. J Neurosurg 71:244-253
20. Gennarelli TA, Thibault LE, Graham DI (1998) Diffuse axonal injury: an important form of traumatic brain damage. Neuroscientist 4:202-215
21. Gentleman SM, Graham DI, Roberts GW (1993) Molecular pathology of head trauma: altered βAPP metabolism and the aetiology of Alzheimer's disease. Prog Brain Res 96:237-246
22. Green SL, Kulp KS, Vulliet R (1997) Cyclin-dependent protein kinase 5 activity increases in rat brain following ischemia. Neurochem Int 31:617-623
23. Harvey PKP, Newsom-Davis J (1974) Traumatic encephalopathy in a young boxer. Lancet II:928-929
24. Hestad K, Updike M, Selnes OA, Royal WR (1995) Cognitive sequelae of repeated head injury in a population of intravenous drug users. Scand J Psychol 36:246-255
25. Hirano A, Zimmerman HM (1962) Alzheimer's neurofibrillary changes: a topographic study. Arch Neurol 7:227-242
26. Hof PR, Knabe R, Bovier P, Bouras C (1991) Neuropathological observations in a case of autism presenting with self-injury behavior. Acta Neuropathol 82:321-326
27. Hof PR, Bouras C, Buee L, Delacourte A, Perl DP, Morrison JH (1992) Differential distribution of neurofibrillary tangles in the cerebral cortex of dementia pugilistica and Alzheimer's disease cases. Acta Neuropathol 85:23-30
28. Hoshino S, Tamaoka A, Masayasu T, Kobayashi S, Furukawa T, Oaki Y, Mori A, Matsuno S, Shoji S, Inomata M, Teramoto A (1998) Emergence of immunoreactivities for phosphorylated tau and amyloid-β protein in chronic stage of fluid percussion injury in rat brain. Neuroreport 9:1879-1883
29. Hyman BT (1997) The neuropathological diagnosis of Alzheimer's disease: clinical-pathological studies. Neurobiol Aging 18:S4, S27-S32
30. Irving EA, Yatsushiro K, McCulloch J, Dewar D (1997) Rapid alteration of tau in oligodendrocytes after focal ischemic injury in the rat: involvement of free radicals. J Cereb Blood Flow Metab 17:612-622
31. Jafari SS, Maxwell WL, Neilson M, Graham DI (1997) Axonal cytoskeletal changes after non-disruptive axonal injury. J Neurocytol 26:207-221
32. Jordan BD, Relkin NR, Ravdin LD, Jacobs AR, Bennett A, Gandy S (1997) Apolipoprolein E epsilon 4 associated with chronic traumatic brain injury in boxing. JAMA 278:136-140
33. Kanayama G, Takeda M, Niigawa H, Ikura Y, Tamii H, Taniguchi N, Kudo T, Miyamae Y, Morihara T, Nishimura T (1996) The effects of repetitive mild brain injury on cytoskeletal protein and behavior. Methods Find Exp Clin Pharmacol 18: 105-115
34. Kaste M, Kuurne T, Vilkki J, Katevuo K, Sainio K, Meurala H (1982) Is chronic brain damage in boxing a hazard of the past? Lancet II:1186-1188
35. Matser JT, Kessels AGH, Jordan BD, Lezak MD, Troost J (1998) Chronic traumatic brain injury in professional soccer players. Neurology 51:791-796
36. Maxwell WL, Graham DI (1996) Loss of axonal microtubules after stretch injury. Neuropathol Appl Neurobiol 22:158-159
37. Maxwell WL, Irvine A, Graham DI, Adams JH, Gennarelli TA, Tipperman R, Sturatis M (1991) Focal axonal injury: the early axonal response to stretch. J Neurocytol 20:157-164
38. Maxwell WL, McCreath BJ, Graham DI, Gennarelli TA (1995) Cytochemical evidence for redistribution of membrane pump calcium-ATPase and ecto-Ca-ATPase activity, and calcium influx in myelinated nerve fibres of the optic nerve after stretch injury. J Neurocytol 24:925-942
39. Maxwell WL, Povlishock JT, Graham DL (1997) A mechanistic analysis of nondisruptive axonal injury: a review. J Neurotrauma 14:419-440
40. McKenzie JE, Gentleman SM, Roberts GW, Graham DI, Royston MC (1994) Increased numbers of βAPP-immunoreactive neurones in the entorhinal cortex after head injury. Neuroreport 6:161-164
41. Mulot SF, Hughes K, Woodgett JR, Anderton BH, Hanger DP (1994) PHF-tau from Alzheimer's brain comprises four species on SDS-PAGE which can be mimicked by in vitro phosphorylation of human brain tau by glycogen synthase kinase-3 beta. FEBS Lett 349:359-364
42. Nicoll JA, Roberts GW, Graham DI (1995) Apolipoprotein E epsilon 4 allele is associated with deposition of amyloid beta-protein following head injury. Nat Med 1:135-137
43. Nicoll JAR, Burnett C, Love S, Graham DI, Dewar D, Ironside JW, Stewart J, Vinters HV (1997) High frequency of apolipoprotein E epsilon 2 allele in hemorrhage due to cerebral amyloid angiopathy. Ann Neurol 41:716-721
44. Ott L, McClain CJ, Gillespie M, Young B (1994) Cytokines and metabolic dysfunction after severe head injury. J Neurotrauma 11:447-472
45. Parker RS, Rosenblum A (1996) IQ loss and emotional dysfunctions after mild head injury incurred in a motor vehicle accident. J Clin Psychol 52:32-43
46. Povlishock JT, Jenkins LW (1995) Are the pathobiological changes evoked by traumatic brain injury immediate and irreversible? Brain Pathol 5:415-426
47. Povlishock JT, Marmarou A, McIntosh T, Trojanowski JQ, Moroi J (1997) Impact acceleration injury in the rat: evidence for focal axolemmal change and related neurofilament sidearm alteration. J Neuropathol Exp Neurol 56:347-359
48. Révész T, Holton J, Doshi B, Anderton BH, Scaravilli F, Plant GT (1999) Cytoskeletal pathology in familial cerebral amyloid angiopathy (British type) with non-neuritic amyloid plaque formation. Acta Neuropathol 97:170-176
49. Roberts GW (1988) Immunocytochemistry of neurofibrillary tangles in dementia pugilistica and Alzheimer's disease: evidence for common genesis. Lancet II:1456-1458
50. Roberts GW, Allsop D, Bruton C (1990) The occult aftermath of boxing. J Neurol Neurosurg Psychiatry 53:373-378
51. Roberts GW, Whitwell HL, Acland PR, Bruton CJ (1990) Dementia in a punch-drunk wife. Lancet 335:918-919
52. Saatman KE, Graham DI, McIntosh TK (1998) The neuronal cytoskeleton is at risk after mild and moderate brain injury. J Neurotrauma 15:1047-1058
53. Shackelford DA, Nelson KE (1996) Changes in phosphorylation of tau during ischemia and reperfusion in the rabbit spinal cord. J Neurochem 66:286-295
54. Spillantini MG, Crowther RA, Goedert M (1996) Comparison of the neurofibrillary pathology in Alzheimer's disease and familial presenile dementia with tangles. Acta Neuropathol 92: 42-48
55. Teasdale GM, Nicoll JAR, Murray G, Fiddes M (1997) Association of apolipoprotein E polymorphism with outcome after head injury. Lancet 350:1069-1071
56. Tokuda T, Ikeda S, Yanagisawa N, Ihara Y, Glenner GG (1991) Re-examination of ex-boxers' brains using immunohistochemistry with antibodies to amyloid beta-protein and tau protein. Acta Neuropathol 82:280-285
57. Tysvaer AT, Storli OV (1989) Soccer injuries to the brain. A neurologic and electroencephalographic study of active football players. Am J Sports Med 17:573-578
58. Tysvaer AT, Sortland O, Storli OV, Lochen EA (1992) Head and neck injuries among Norwegian soccer players. A neurological, electroencephalographic, radiologic and neuropsychological evaluation. Tidsskr Nor Laegeforen 112:1268-1271
59. Uchihara T, Tsuchiya K, Kondo H, Hayama T, Ikeda K (1995) Widespread appearance of Alz-50 immunoreactive neurons in the human brain with cerebral infarction. Stroke 26:2145-2148
60. Wilberger JE (1993) Minor head injuries in American football. Prevention of long term sequelae. Sports Med 15:338-343
61. Williams DJ, Tannenberg AE (1996) Dementia pugilistica in an alcoholic achondroplastic dwarf. Pathology 28:102-104
62. Wisniewski HM, Narang HK, Corsellis JAN, Terry RD (1976) Ultrastructural studies of the neuropil and neurofibrillary tangles in Alzheimer's disease and post-traumatic dementia. J Neuropathol Exp Neurol 35:367
63. Wrightson P, McGinn V, Gronwall D (1995) Mild head injury in preschool children: evidence that it can be associated with a persisting cognitive defect. J Neurol Neurosurg Psychiatry 59: 375-380