-
1
-
-
84923587888
-
International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors
-
Hamann J, Aust G, Arac D, Engel FB, Formstone C et al (2015) International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors. Pharmacol Rev 67:338-367
-
(2015)
Pharmacol Rev
, vol.67
, pp. 338-367
-
-
Hamann, J.1
Aust, G.2
Arac, D.3
Engel, F.B.4
Formstone, C.5
-
3
-
-
0034213071
-
LNB-TM7, a group of seventransmembrane proteins related to family-B G-protein-coupled receptors
-
Stacey M, Lin HH, Gordon S, McKnight AJ (2000) LNB-TM7, a group of seventransmembrane proteins related to family-B G-protein-coupled receptors. Trends Biochem Sci 25:284-289
-
(2000)
Trends Biochem Sci
, vol.25
, pp. 284-289
-
-
Stacey, M.1
Lin, H.H.2
Gordon, S.3
McKnight, A.J.4
-
4
-
-
0030589320
-
CD97 is a processed, seventransmembrane, heterodimeric receptor associated with inflammation
-
Gray JX, Haino M, Roth MJ, Maguire JE, Jensen PN et al (1996) CD97 is a processed, seventransmembrane, heterodimeric receptor associated with inflammation. J Immunol 157:5438-5447
-
(1996)
J Immunol
, vol.157
, pp. 5438-5447
-
-
Gray, J.X.1
Haino, M.2
Roth, M.J.3
Maguire, J.E.4
Jensen, P.N.5
-
5
-
-
0031006123
-
Salnikow KV et al (1997) alpha-Latrotoxin stimulates exocytosis by the interaction with a neuronal G-protein-coupled receptor
-
Krasnoperov V, Bittner MA, Beavis R, Kuang Y, Salnikow KV et al (1997) alpha-Latrotoxin stimulates exocytosis by the interaction with a neuronal G-protein-coupled receptor. Neuron 18:925-937
-
Neuron
, vol.18
, pp. 925-937
-
-
Krasnoperov, V.1
Bittner, M.A.2
Beavis, R.3
Kuang, Y.4
-
6
-
-
0033525112
-
Structural requirements for alpha-latrotoxin binding and alpha-latrotoxin-stimulated secretion. A study with calcium-independent receptor of alpha-latrotoxin (CIRL) deletion mutants
-
Krasnoperov V, Bittner MA, Holz RW, Chepurny O, Petrenko AG (1999) Structural requirements for alpha-latrotoxin binding and alpha-latrotoxin-stimulated secretion. A study with calcium-independent receptor of alpha-latrotoxin (CIRL) deletion mutants. J Biol Chem 274:3590-3596
-
(1999)
J Biol Chem
, vol.274
, pp. 3590-3596
-
-
Krasnoperov, V.1
Bittner, M.A.2
Holz, R.W.3
Chepurny, O.4
Petrenko, A.G.5
-
7
-
-
0038642821
-
Proteolytic cleavage of the EMR2 receptor requires both the extracellular stalk and the GPS motif
-
Chang GW, Stacey M, Kwakkenbos MJ, Hamann J, Gordon S et al (2003) Proteolytic cleavage of the EMR2 receptor requires both the extracellular stalk and the GPS motif. FEBS Lett 547:145-150
-
(2003)
FEBS Lett
, vol.547
, pp. 145-150
-
-
Chang, G.W.1
Stacey, M.2
Kwakkenbos, M.J.3
Hamann, J.4
Gordon, S.5
-
8
-
-
0028641336
-
Autoproteolysis in hedgehog protein biogenesis
-
Lee JJ, Ekker SC, von Kessler DP, Porter JA, Sun BI et al (1994) Autoproteolysis in hedgehog protein biogenesis. Science 266:1528-1537
-
(1994)
Science
, vol.266
, pp. 1528-1537
-
-
Lee, J.J.1
Ekker, S.C.2
Von Kessler, D.P.3
Porter, J.A.4
Sun, B.I.5
-
9
-
-
0028948811
-
The product of hedgehog autoproteolytic cleavage active in local and long-range signalling
-
Porter JA, von Kessler DP, Ekker SC, Young KE, Lee JJ et al (1995) The product of hedgehog autoproteolytic cleavage active in local and long-range signalling. Nature 374:363-366
-
(1995)
Nature
, vol.374
, pp. 363-366
-
-
Porter, J.A.1
Von Kessler, D.P.2
Ekker, S.C.3
Young, K.E.4
Lee, J.J.5
-
10
-
-
0030051163
-
Activation of glycosylasparaginase. Formation of active N-terminal threonine by intramolecular autoproteolysis
-
Guan C, Cui T, Rao V, Liao W, Benner J et al (1996) Activation of glycosylasparaginase. Formation of active N-terminal threonine by intramolecular autoproteolysis. J Biol Chem 271:1732-1737
-
(1996)
J Biol Chem
, vol.271
, pp. 1732-1737
-
-
Guan, C.1
Cui, T.2
Rao, V.3
Liao, W.4
Benner, J.5
-
11
-
-
3843101589
-
Autocatalytic cleavage of the EMR2 receptor occurs at a conserved G protein-coupled receptor proteolytic site motif
-
Lin HH, Chang GW, Davies JQ, Stacey M, Harris J et al (2004) Autocatalytic cleavage of the EMR2 receptor occurs at a conserved G protein-coupled receptor proteolytic site motif. J Biol Chem 279:31823-31832
-
(2004)
J Biol Chem
, vol.279
, pp. 31823-31832
-
-
Lin, H.H.1
Chang, G.W.2
Davies, J.Q.3
Stacey, M.4
Harris, J.5
-
12
-
-
0028786346
-
Three-dimensional structure of human lysosomal aspartylglucosaminidase
-
Oinonen C, Tikkanen R, Rouvinen J, Peltonen L (1995) Three-dimensional structure of human lysosomal aspartylglucosaminidase. Nat Struct Biol 2:1102-1108
-
(1995)
Nat Struct Biol
, vol.2
, pp. 1102-1108
-
-
Oinonen, C.1
Tikkanen, R.2
Rouvinen, J.3
Peltonen, L.4
-
13
-
-
0029936212
-
Functional analyses of active site residues of human lysosomal aspartylglucosaminidase: Implications for catalytic mechanism and autocatalytic activation
-
Tikkanen R, Riikonen A, Oinonen C, Rouvinen R, Peltonen L (1996) Functional analyses of active site residues of human lysosomal aspartylglucosaminidase: implications for catalytic mechanism and autocatalytic activation. EMBO J 15:2954-2960
-
(1996)
EMBO J
, vol.15
, pp. 2954-2960
-
-
Tikkanen, R.1
Riikonen, A.2
Oinonen, C.3
Rouvinen, R.4
Peltonen, L.5
-
14
-
-
0033520327
-
Structural insights into the mechanism of intramolecular proteolysis
-
Xu Q, Buckley D, Guan C, Guo HC (1999) Structural insights into the mechanism of intramolecular proteolysis. Cell 98:651-661
-
(1999)
Cell
, vol.98
, pp. 651-661
-
-
Xu, Q.1
Buckley, D.2
Guan, C.3
Guo, H.C.4
-
15
-
-
0037195853
-
Posttranslational proteolytic processing of the calcium-independent receptor of alpha-latrotoxin (CIRL), a natural chimera of the cell adhesion protein and the G protein-coupled receptor. Role of the G protein-coupled receptor proteolysis site (GPS) motif
-
Krasnoperov V, Lu Y, Buryanovsky L, Neubert TA, Ichtchenko K et al (2002) Posttranslational proteolytic processing of the calcium-independent receptor of alpha-latrotoxin (CIRL), a natural chimera of the cell adhesion protein and the G protein-coupled receptor. Role of the G protein-coupled receptor proteolysis site (GPS) motif. J Biol Chem 277:46518-46526
-
(2002)
J Biol Chem
, vol.277
, pp. 46518-46526
-
-
Krasnoperov, V.1
Lu, Y.2
Buryanovsky, L.3
Neubert, T.A.4
Ichtchenko, K.5
-
16
-
-
47249103800
-
Orphan G protein-coupled receptor GPR56 regulates neural progenitor cell migration via a G alpha 12/13 and Rho pathway
-
Iguchi T, Sakata K, Yoshizaki K, Tago K, Mizuno N et al (2008) Orphan G protein-coupled receptor GPR56 regulates neural progenitor cell migration via a G alpha 12/13 and Rho pathway. J Biol Chem 283:14469-14478
-
(2008)
J Biol Chem
, vol.283
, pp. 14469-14478
-
-
Iguchi, T.1
Sakata, K.2
Yoshizaki, K.3
Tago, K.4
Mizuno, N.5
-
17
-
-
0037168674
-
Cleavage of polycystin-1 requires the receptor for egg jelly domain and is disrupted by human autosomal-dominant polycystic kidney disease 1-associated mutations
-
Qian F, Boletta A, Bhunia AK, Xu H, Liu L et al (2002) Cleavage of polycystin-1 requires the receptor for egg jelly domain and is disrupted by human autosomal-dominant polycystic kidney disease 1-associated mutations. Proc Natl Acad Sci U S A 99:16981-16986
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 16981-16986
-
-
Qian, F.1
Boletta, A.2
Bhunia, A.K.3
Xu, H.4
Liu, L.5
-
18
-
-
36749047485
-
Essential role of cleavage of Polycystin-1 at G protein-coupled receptor proteolytic site for kidney tubular structure
-
Yu S, Hackmann K, Gao J, He X, Piontek K et al (2007) Essential role of cleavage of Polycystin-1 at G protein-coupled receptor proteolytic site for kidney tubular structure. Proc Natl Acad Sci U S A 104:18688-18693
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 18688-18693
-
-
Yu, S.1
Hackmann, K.2
Gao, J.3
He, X.4
Piontek, K.5
-
19
-
-
84858792464
-
A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis
-
Arac D, Boucard AA, Bolliger MF, Nguyen J, Soltis SM et al (2012) A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis. EMBO J 31:1364-1378
-
(2012)
EMBO J
, vol.31
, pp. 1364-1378
-
-
Arac, D.1
Boucard, A.A.2
Bolliger, M.F.3
Nguyen, J.4
Soltis, S.M.5
-
20
-
-
70349472909
-
Site-specific N-glycosylation regulates the GPS auto-proteolysis of CD 97
-
Hsiao CC, Cheng KF, Chen HY, Chou YH, Stacey M et al (2009) Site-specific N-glycosylation regulates the GPS auto-proteolysis of CD 97. FEBS Lett 583:3285-3290
-
(2009)
FEBS Lett
, vol.583
, pp. 3285-3290
-
-
Hsiao, C.C.1
Cheng, K.F.2
Chen, H.Y.3
Chou, Y.H.4
Stacey, M.5
-
21
-
-
34547580803
-
Characterization of cis-autoproteolysis of polycystin-1, the product of human polycystic kidney disease 1 gene
-
Wei W, Hackmann K, Xu H, Germino G, Qian F (2007) Characterization of cis-autoproteolysis of polycystin-1, the product of human polycystic kidney disease 1 gene. J Biol Chem 282:21729-21737
-
(2007)
J Biol Chem
, vol.282
, pp. 21729-21737
-
-
Wei, W.1
Hackmann, K.2
Xu, H.3
Germino, G.4
Qian, F.5
-
22
-
-
77649184579
-
Regulation of CIRL-1 proteolysis and trafficking
-
Deyev IE, Petrenko AG (2010) Regulation of CIRL-1 proteolysis and trafficking. Biochimie 92:418-422
-
(2010)
Biochimie
, vol.92
, pp. 418-422
-
-
Deyev, I.E.1
Petrenko, A.G.2
-
23
-
-
84995422294
-
Understanding the structural basis of adhesion GPCR functions
-
Langenhan T, Schöneberg T, Springer, Heidelberg
-
Araç D, Sträter N, Seiradake E. (2016) Understanding the structural basis of adhesion GPCR functions. In: Langenhan T, Schöneberg T (eds) Adhesion G protein-coupled receptors: molecular, physiological and pharmacological principles in health and disease. Springer, Heidelberg
-
(2016)
Adhesion G Protein-Coupled Receptors: Molecular, Physiological and Pharmacological Principles in Health and Disease
-
-
Araç, D.1
Sträter, N.2
Seiradake, E.3
-
24
-
-
84881169511
-
Matching structure with function: The GAIN domain of adhesion-GPCR and PKD1-like proteins
-
Prömel S, Langenhan T, Arac D (2013) Matching structure with function: the GAIN domain of adhesion-GPCR and PKD1-like proteins. Trends Pharmacol Sci 34:470-478
-
(2013)
Trends Pharmacol Sci
, vol.34
, pp. 470-478
-
-
Prömel, S.1
Langenhan, T.2
Arac, D.3
-
25
-
-
84878318013
-
Sticky signaling-adhesion class G protein-coupled receptors take the stage
-
re3
-
Langenhan T, Aust G, Hamann J (2013) Sticky signaling-adhesion class G protein-coupled receptors take the stage. Sci Signal 6:re3
-
(2013)
Sci Signal
, vol.6
-
-
Langenhan, T.1
Aust, G.2
Hamann, J.3
-
26
-
-
77955660663
-
Diverse somatic mutation patterns and pathway alterations in human cancers
-
Kan Z, Jaiswal BS, Stinson J, Janakiraman V, Bhatt D et al (2010) Diverse somatic mutation patterns and pathway alterations in human cancers. Nature 466:869-873
-
(2010)
Nature
, vol.466
, pp. 869-873
-
-
Kan, Z.1
Jaiswal, B.S.2
Stinson, J.3
Janakiraman, V.4
Bhatt, D.5
-
27
-
-
12144286654
-
G protein-coupled receptor-dependent development of human frontal cortex
-
Piao X, Hill RS, Bodell A, Chang BS, Basel-Vanagaite L et al (2004) G protein-coupled receptor-dependent development of human frontal cortex. Science 303:2033-2036
-
(2004)
Science
, vol.303
, pp. 2033-2036
-
-
Piao, X.1
Hill, R.S.2
Bodell, A.3
Chang, B.S.4
Basel-Vanagaite, L.5
-
28
-
-
0037189505
-
Cleavage of Ig-Hepta at a “SEA” module and at a conserved G protein-coupled receptor proteolytic site
-
Abe J, Fukuzawa T, Hirose S (2002) Cleavage of Ig-Hepta at a “SEA” module and at a conserved G protein-coupled receptor proteolytic site. J Biol Chem 277:23391-23398
-
(2002)
J Biol Chem
, vol.277
, pp. 23391-23398
-
-
Abe, J.1
Fukuzawa, T.2
Hirose, S.3
-
29
-
-
0029013157
-
The SEA module: A new extracellular domain associated with O-glycosylation
-
Bork P, Patthy L (1995) The SEA module: a new extracellular domain associated with O-glycosylation. Protein Sci 4:1421-1425
-
(1995)
Protein Sci
, vol.4
, pp. 1421-1425
-
-
Bork, P.1
Patthy, L.2
-
30
-
-
0038630508
-
SEA (Sea-urchin sperm protein, enterokinase and agrin)-module cleavage, association of fragments and membrane targeting of rat intestinal mucin Muc 3
-
Khatri IA, Wang R, Forstner JF (2003) SEA (sea-urchin sperm protein, enterokinase and agrin)-module cleavage, association of fragments and membrane targeting of rat intestinal mucin Muc 3. Biochem J 372:263-270
-
(2003)
Biochem J
, vol.372
, pp. 263-270
-
-
Khatri, I.A.1
Wang, R.2
Forstner, J.F.3
-
31
-
-
20444445503
-
The role of the SEA (Sea urchin sperm protein, enterokinase and agrin) module in cleavage of membranetethered mucins
-
Palmai-Pallag T, Khodabukus N, Kinarsky L, Leir SH, Sherman S et al (2005) The role of the SEA (sea urchin sperm protein, enterokinase and agrin) module in cleavage of membranetethered mucins. FEBS J 272:2901-2911
-
(2005)
FEBS J
, vol.272
, pp. 2901-2911
-
-
Palmai-Pallag, T.1
Khodabukus, N.2
Kinarsky, L.3
Leir, S.H.4
Sherman, S.5
-
32
-
-
18244382351
-
Generation of ligand-receptor alliances by “SEA” module-mediated cleavage of membrane-associated mucin proteins
-
Wreschner DH, McGuckin MA, Williams SJ, Baruch A, Yoeli M et al (2002) Generation of ligand-receptor alliances by “SEA” module-mediated cleavage of membrane-associated mucin proteins. Protein Sci 11:698-706
-
(2002)
Protein Sci
, vol.11
, pp. 698-706
-
-
Wreschner, D.H.1
McGuckin, M.A.2
Williams, S.J.3
Baruch, A.4
Yoeli, M.5
-
33
-
-
25844434734
-
The MUC1 SEA module is a self-cleaving domain
-
Levitin F, Stern O, Weiss M, Gil-Henn C, Ziv R et al (2005) The MUC1 SEA module is a self-cleaving domain. J Biol Chem 280:33374-33386
-
(2005)
J Biol Chem
, vol.280
, pp. 33374-33386
-
-
Levitin, F.1
Stern, O.2
Weiss, M.3
Gil-Henn, C.4
Ziv, R.5
-
34
-
-
67650480533
-
Protein autoproteolysis: Conformational strain linked to the rate of peptide cleavage by the pH dependence of the
-
Johansson DG, Wallin G, Sandberg A, Macao B, Aqvist J et al (2009) Protein autoproteolysis: conformational strain linked to the rate of peptide cleavage by the pH dependence of the N ! O acyl shift reaction. J Am Chem Soc 131:9475-9477
-
(2009)
N ! O Acyl Shift Reaction. J am Chem Soc
, vol.131
, pp. 9475-9477
-
-
Johansson, D.G.1
Wallin, G.2
Sandberg, A.3
Macao, B.4
Aqvist, J.5
-
35
-
-
30044448792
-
Autoproteolysis coupled to protein folding in the SEA domain of the membrane-bound MUC1 mucin
-
Macao B, Johansson DG, Hansson GC, Hard T (2006) Autoproteolysis coupled to protein folding in the SEA domain of the membrane-bound MUC1 mucin. Nat Struct Mol Biol 13:71-76
-
(2006)
Nat Struct Mol Biol
, vol.13
, pp. 71-76
-
-
Macao, B.1
Johansson, D.G.2
Hansson, G.C.3
Hard, T.4
-
36
-
-
40849101413
-
SEA domain autoproteolysis accelerated by conformational strain: Mechanistic aspects
-
Johansson DG, Macao B, Sandberg A, Hard T (2008) SEA domain autoproteolysis accelerated by conformational strain: mechanistic aspects. J Mol Biol 377:1130-1143
-
(2008)
J Mol Biol
, vol.377
, pp. 1130-1143
-
-
Johansson, D.G.1
Macao, B.2
Sandberg, A.3
Hard, T.4
-
37
-
-
40849087605
-
SEA domain autoproteolysis accelerated by conformational strain: Energetic aspects
-
Sandberg A, Johansson DG, Macao B, Hard T (2008) SEA domain autoproteolysis accelerated by conformational strain: energetic aspects. J Mol Biol 377:1117-1129
-
(2008)
J Mol Biol
, vol.377
, pp. 1117-1129
-
-
Sandberg, A.1
Johansson, D.G.2
Macao, B.3
Hard, T.4
-
38
-
-
33750719111
-
Multiple processing of Ig-Hepta/GPR116, a G protein-coupled receptor with immunoglobulin (Ig)-like repeats, and generation of EGF2-like fragment
-
Fukuzawa T, Hirose S (2006) Multiple processing of Ig-Hepta/GPR116, a G protein-coupled receptor with immunoglobulin (Ig)-like repeats, and generation of EGF2-like fragment. J Biochem 140:445-452
-
(2006)
J Biochem
, vol.140
, pp. 445-452
-
-
Fukuzawa, T.1
Hirose, S.2
-
39
-
-
84928408901
-
Targeted disruption of Ig-Hepta/ Gpr116 causes emphysema-like symptoms that are associated with alveolar macrophage activation
-
Ariestanti DM, Ando H, Hirose S, Nakamura N (2015) Targeted disruption of Ig-Hepta/ Gpr116 causes emphysema-like symptoms that are associated with alveolar macrophage activation. J Biol Chem 290:11032-11040
-
(2015)
J Biol Chem
, vol.290
, pp. 11032-11040
-
-
Ariestanti, D.M.1
Ando, H.2
Hirose, S.3
Nakamura, N.4
-
40
-
-
84880839405
-
Orphan G protein-coupled receptor GPR116 regulates pulmonary surfactant pool size
-
Bridges JP, Ludwig MG, Mueller M, Kinzel B, Sato A et al (2013) Orphan G protein-coupled receptor GPR116 regulates pulmonary surfactant pool size. Am J Respir Cell Mol Biol 49:348-357
-
(2013)
Am J Respir Cell Mol Biol
, vol.49
, pp. 348-357
-
-
Bridges, J.P.1
Ludwig, M.G.2
Mueller, M.3
Kinzel, B.4
Sato, A.5
-
41
-
-
84880794212
-
Lung surfactant levels are regulated by Ig-Hepta/GPR116 by monitoring surfactant protein D
-
Fukuzawa T, Ishida J, Kato A, Ichinose T, Ariestanti DM et al (2013) Lung surfactant levels are regulated by Ig-Hepta/GPR116 by monitoring surfactant protein D. PLoS One 8, e69451
-
(2013)
Plos One
, pp. 8
-
-
Fukuzawa, T.1
Ishida, J.2
Kato, A.3
Ichinose, T.4
Ariestanti, D.M.5
-
42
-
-
84867577749
-
Adipose tissue deletion of Gpr116 impairs insulin sensitivity through modulation of adipose function
-
Nie T, Hui X, Gao X, Li K, Lin W et al (2012) Adipose tissue deletion of Gpr116 impairs insulin sensitivity through modulation of adipose function. FEBS Lett 586:3618-3625
-
(2012)
FEBS Lett
, vol.586
, pp. 3618-3625
-
-
Nie, T.1
Hui, X.2
Gao, X.3
Li, K.4
Lin, W.5
-
43
-
-
84886066175
-
GPR116, an adhesion G-protein-coupled receptor, promotes breast cancer metastasis via the Galphaq-p63RhoGEF-Rho GTPase pathway
-
Tang X, Jin R, Qu G, Wang X, Li Z et al (2013) GPR116, an adhesion G-protein-coupled receptor, promotes breast cancer metastasis via the Galphaq-p63RhoGEF-Rho GTPase pathway. Cancer Res 73:6206-6218
-
(2013)
Cancer Res
, vol.73
, pp. 6206-6218
-
-
Tang, X.1
Jin, R.2
Qu, G.3
Wang, X.4
Li, Z.5
-
44
-
-
84878589406
-
Essential regulation of lung surfactant homeostasis by the orphan G protein-coupled receptor GPR 116
-
Yang MY, Hilton MB, Seaman S, Haines DC, Nagashima K et al (2013) Essential regulation of lung surfactant homeostasis by the orphan G protein-coupled receptor GPR 116. Cell Rep 3:1457-1464
-
(2013)
Cell Rep
, vol.3
, pp. 1457-1464
-
-
Yang, M.Y.1
Hilton, M.B.2
Seaman, S.3
Haines, D.C.4
Nagashima, K.5
-
45
-
-
84871234437
-
A proprotein convertase/MMP- 14 proteolytic cascade releases a novel 40 kDa vasculostatin from tumor suppressor BAI 1
-
Cork SM, Kaur B, Devi NS, Cooper L, Saltz JH et al (2012) A proprotein convertase/MMP- 14 proteolytic cascade releases a novel 40 kDa vasculostatin from tumor suppressor BAI 1. Oncogene 31:5144-5152
-
(2012)
Oncogene
, vol.31
, pp. 5144-5152
-
-
Cork, S.M.1
Kaur, B.2
Devi, N.S.3
Cooper, L.4
Saltz, J.H.5
-
46
-
-
65249164068
-
Dissociation of the subunits of the calcium-independent receptor of alpha-latrotoxin as a result of two-step proteolysis
-
Krasnoperov V, Deyev IE, Serova OV, Xu C, Lu Y et al (2009) Dissociation of the subunits of the calcium-independent receptor of alpha-latrotoxin as a result of two-step proteolysis. Biochemistry 48:3230-3238
-
(2009)
Biochemistry
, vol.48
, pp. 3230-3238
-
-
Krasnoperov, V.1
Deyev, I.E.2
Serova, O.V.3
Xu, C.4
Lu, Y.5
-
47
-
-
3042772969
-
DREG, a developmentally regulated G protein-coupled receptor containing two conserved proteolytic cleavage sites
-
Moriguchi T, Haraguchi K, Ueda N, Okada M, Furuya T et al (2004) DREG, a developmentally regulated G protein-coupled receptor containing two conserved proteolytic cleavage sites. Genes Cells 9:549-560
-
(2004)
Genes Cells
, vol.9
, pp. 549-560
-
-
Moriguchi, T.1
Haraguchi, K.2
Ueda, N.3
Okada, M.4
Furuya, T.5
-
48
-
-
77951639349
-
Brain-specific angiogenesis inhibitor 2 (BAI2) may be activated by proteolytic processing
-
Okajima D, Kudo G, Yokota H (2010) Brain-specific angiogenesis inhibitor 2 (BAI2) may be activated by proteolytic processing. J Recept Signal Transduct Res 30:143-153
-
(2010)
J Recept Signal Transduct Res
, vol.30
, pp. 143-153
-
-
Okajima, D.1
Kudo, G.2
Yokota, H.3
-
49
-
-
0036791359
-
Furin at the cutting edge: From protein traffic to embryogenesis and disease
-
Thomas G (2002) Furin at the cutting edge: from protein traffic to embryogenesis and disease. Nat Rev Mol Cell Biol 3:753-766
-
(2002)
Nat Rev Mol Cell Biol
, vol.3
, pp. 753-766
-
-
Thomas, G.1
-
50
-
-
19944379133
-
Vasculostatin, a proteolytic fragment of brain angiogenesis inhibitor 1, is an antiangiogenic and antitumorigenic factor
-
Kaur B, Brat DJ, Devi NS, Van Meir EG (2005) Vasculostatin, a proteolytic fragment of brain angiogenesis inhibitor 1, is an antiangiogenic and antitumorigenic factor. Oncogene 24:3632-3642
-
(2005)
Oncogene
, vol.24
, pp. 3632-3642
-
-
Kaur, B.1
Brat, D.J.2
Devi, N.S.3
van Meir, E.G.4
-
51
-
-
9844261161
-
A novel brain-specific p53-target gene, BAI1, containing thrombospondin type 1 repeats inhibits experimental angiogenesis
-
Nishimori H, Shiratsuchi T, Urano T, Kimura Y, Kiyono K et al (1997) A novel brain-specific p53-target gene, BAI1, containing thrombospondin type 1 repeats inhibits experimental angiogenesis. Oncogene 15:2145-2150
-
(1997)
Oncogene
, vol.15
, pp. 2145-2150
-
-
Nishimori, H.1
Shiratsuchi, T.2
Urano, T.3
Kimura, Y.4
Kiyono, K.5
-
52
-
-
84919876223
-
A tethered agonist within the ectodomain activates the adhesion G protein-coupled receptors GPR126 and GPR 133
-
Liebscher I, Schön J, Petersen SC, Fischer L, Auerbach N et al (2014) A tethered agonist within the ectodomain activates the adhesion G protein-coupled receptors GPR126 and GPR 133. Cell Rep 9:2018-2026
-
(2014)
Cell Rep
, vol.9
, pp. 2018-2026
-
-
Liebscher, I.1
Schön, J.2
Petersen, S.C.3
Fischer, L.4
Auerbach, N.5
-
53
-
-
82755167752
-
Cell adhesion receptor GPR133 couples to Gs protein
-
Bohnekamp J, Schöneberg T (2011) Cell adhesion receptor GPR133 couples to Gs protein. J Biol Chem 286:41912-41916
-
(2011)
J Biol Chem
, vol.286
, pp. 41912-41916
-
-
Bohnekamp, J.1
Schöneberg, T.2
-
54
-
-
84865768212
-
The GPS motif is a molecular switch for bimodal activities of adhesion class G protein-coupled receptors
-
Prömel S, Frickenhaus M, Hughes S, Mestek L, Staunton D et al (2012) The GPS motif is a molecular switch for bimodal activities of adhesion class G protein-coupled receptors. Cell Rep 2:321-331
-
(2012)
Cell Rep
, vol.2
, pp. 321-331
-
-
Prömel, S.1
Frickenhaus, M.2
Hughes, S.3
Mestek, L.4
Staunton, D.5
-
55
-
-
84915779680
-
Novel functional complexity of polycystin-1 by GPS cleavage in vivo: Role in polycystic kidney disease
-
Kurbegovic A, Kim H, Xu H, Yu S, Cruanès J et al (2014) Novel functional complexity of polycystin-1 by GPS cleavage in vivo: role in polycystic kidney disease. Mol Cell Biol 34:3341-3353
-
(2014)
Mol Cell Biol
, vol.34
, pp. 3341-3353
-
-
Kurbegovic, A.1
Kim, H.2
Xu, H.3
Yu, S.4
Cruanès, J.5
-
56
-
-
10044265266
-
Latrophilin fragments behave as independent proteins that associate and signal on binding of LTX(N4C)
-
Volynski KE, Silva JP, Lelianova VG, Atiqur Rahman M, Hopkins C et al (2004) Latrophilin fragments behave as independent proteins that associate and signal on binding of LTX(N4C). EMBO J 23:4423-4433
-
(2004)
EMBO J
, vol.23
, pp. 4423-4433
-
-
Volynski, K.E.1
Silva, J.P.2
Lelianova, V.G.3
Atiqur Rahman, M.4
Hopkins, C.5
-
57
-
-
84878324673
-
Forces in tissue morphogenesis and patterning
-
Heisenberg CP, Bellaiche Y (2013) Forces in tissue morphogenesis and patterning. Cell 153:948-962
-
(2013)
Cell
, vol.153
, pp. 948-962
-
-
Heisenberg, C.P.1
Bellaiche, Y.2
-
58
-
-
84995404823
-
Tethered agonism: A common activation mechanism of adhesion GPCRs
-
Langenhan T, Schöneberg T, Springer, Heidelberg
-
Liebscher I, Schöneberg T (2016) Tethered agonism: a common activation mechanism of adhesion GPCRs. In: Langenhan T, Schöneberg T (eds) Adhesion G protein-coupled receptors: molecular, physiological and pharmacological principles in health and disease. Springer, Heidelberg
-
(2016)
Adhesion G Protein-Coupled Receptors: Molecular, Physiological and Pharmacological Principles in Health and Disease
-
-
Liebscher, I.1
Schöneberg, T.2
-
59
-
-
84995378102
-
Versatile signaling activity of adhesion GPCRs
-
Langenhan T, Schöneberg T, Springer, Heidelberg
-
Kishore A, Hall RA (2016) Versatile signaling activity of adhesion GPCRs. In: Langenhan T, Schöneberg T (eds) Adhesion G protein-coupled receptors: molecular, physiological and pharmacological principles in health and disease. Springer, Heidelberg
-
(2016)
Adhesion G Protein-Coupled Receptors: Molecular, Physiological and Pharmacological Principles in Health and Disease
-
-
Kishore, A.1
Hall, R.A.2
-
60
-
-
80051703577
-
The N terminus of the adhesion G protein-coupled receptor GPR56 controls receptor signaling activity
-
Paavola KJ, Stephenson JR, Ritter SL, Alter SP, Hall RA (2011) The N terminus of the adhesion G protein-coupled receptor GPR56 controls receptor signaling activity. J Biol Chem 286:28914-28921
-
(2011)
J Biol Chem
, vol.286
, pp. 28914-28921
-
-
Paavola, K.J.1
Stephenson, J.R.2
Ritter, S.L.3
Alter, S.P.4
Hall, R.A.5
-
61
-
-
84871505599
-
Dissecting signaling and functions of adhesion G protein-coupled receptors
-
Arac D, Aust G, Calebiro D, Engel FB, Formstone C et al (2012) Dissecting signaling and functions of adhesion G protein-coupled receptors. Ann N Y Acad Sci 1276:1-25
-
(2012)
Ann N Y Acad Sci
, vol.1276
, pp. 1-25
-
-
Arac, D.1
Aust, G.2
Calebiro, D.3
Engel, F.B.4
Formstone, C.5
-
62
-
-
84995388339
-
Adhesion GPCRs govern polarity of epithelia and cell migration
-
Langenhan T, Schöneberg T, Springer, Heidelberg
-
Strutt D, Schnabel R, Fiedler F, Prömel S (2016) Adhesion GPCRs govern polarity of epithelia and cell migration. In: Langenhan T, Schöneberg T (eds) Adhesion G proteincoupled receptors: molecular, physiological and pharmacological principles in health and disease. Springer, Heidelberg
-
(2016)
Adhesion G Proteincoupled Receptors: Molecular, Physiological and Pharmacological Principles in Health and Disease
-
-
Strutt, D.1
Schnabel, R.2
Fiedler, F.3
Prömel, S.4
-
63
-
-
84929208101
-
Adhesion G protein-coupled receptors are activated by exposure of a cryptic tethered agonist
-
Stoveken HM, Hajduczok AG, Xu L, Tall GG (2015) Adhesion G protein-coupled receptors are activated by exposure of a cryptic tethered agonist. Proc Natl Acad Sci U S A 112:6194-6199
-
(2015)
Proc Natl Acad Sci U S A
, vol.112
, pp. 6194-6199
-
-
Stoveken, H.M.1
Hajduczok, A.G.2
Xu, L.3
Tall, G.G.4
-
64
-
-
84938751168
-
Identification of the tethered peptide agonist of the adhesion G protein-coupled receptor GPR64/ADGRG 2
-
Demberg LM, Rothemund S, Schöneberg T, Liebscher I (2015) Identification of the tethered peptide agonist of the adhesion G protein-coupled receptor GPR64/ADGRG 2. Biochem Biophys Res Commun 464:743-747
-
(2015)
Biochem Biophys Res Commun
, vol.464
, pp. 743-747
-
-
Demberg, L.M.1
Rothemund, S.2
Schöneberg, T.3
Liebscher, I.4
-
65
-
-
84958778198
-
The constitutive activity of the adhesion GPCR GPR114/ADGRG5 is mediated by its tethered agonist
-
Wilde C, Fischer L, Lede V, Kirchberger J, Rothemund S et al (2016) The constitutive activity of the adhesion GPCR GPR114/ADGRG5 is mediated by its tethered agonist. FASEB J 30(2):666-673
-
(2016)
FASEB J
, vol.30
, Issue.2
, pp. 666-673
-
-
Wilde, C.1
Fischer, L.2
Lede, V.3
Kirchberger, J.4
Rothemund, S.5
-
66
-
-
84946595089
-
Oriented cell division in the C. Elegans embryo is coordinated by G-protein signaling dependent on the adhesion GPCR LAT-1
-
Müller A, Winkler J, Fiedler F, Sastradihardja T, Binder C et al (2015) Oriented cell division in the C. elegans embryo is coordinated by G-protein signaling dependent on the adhesion GPCR LAT-1. PLoS Genet 11:e1005624
-
(2015)
Plos Genet
, vol.11
-
-
Müller, A.1
Winkler, J.2
Fiedler, F.3
Sastradihardja, T.4
Binder, C.5
-
67
-
-
84959017087
-
Vibratory urticaria associated with a missense variant in ADGRE 2
-
Boyden SE, Desai A, Cruse G, Young ML, Bolan HC et al (2016) Vibratory urticaria associated with a missense variant in ADGRE 2. N Engl J Med 374:656-663
-
(2016)
N Engl J Med
, vol.374
, pp. 656-663
-
-
Boyden, S.E.1
Desai, A.2
Cruse, G.3
Young, M.L.4
Bolan, H.C.5
-
68
-
-
84995476541
-
Adhesion GPCRs as modulators of immune cell function
-
Langenhan T, Schöneberg T, Springer, Heidelberg
-
Hamann J, Hsiao C-C, Lee CS, Ravichandran KS, Lin H-H (2016) Adhesion GPCRs as modulators of immune cell function. In: Langenhan T, Schöneberg T (eds) Adhesion G protein-coupled receptors: molecular, physiological and pharmacological principles in health and disease. Springer, Heidelberg
-
(2016)
Adhesion G Protein-Coupled Receptors: Molecular, Physiological and Pharmacological Principles in Health and Disease
-
-
Hamann, J.1
Hsiao, C.-C.2
Lee, C.S.3
Ravichandran, K.S.4
Lin, H.-H.5
-
69
-
-
34247189534
-
Structural basis for autoinhibition of Notch
-
Gordon WR, Vardar-Ulu D, Histen G, Sanchez-Irizarry C, Aster JC et al (2007) Structural basis for autoinhibition of Notch. Nat Struct Mol Biol 14:295-300
-
(2007)
Nat Struct Mol Biol
, vol.14
, pp. 295-300
-
-
Gordon, W.R.1
Vardar-Ulu, D.2
Histen, G.3
Sanchez-Irizarry, C.4
Aster, J.C.5
-
70
-
-
84964679035
-
Stalk-dependent and stalkindependent signaling by the adhesion G protein-coupled receptors GPR56 (ADGRG1) and BAI1 (ADGRB1)
-
Kishore A, Purcell RH, Nassiri-Toosi Z, Hall RA (2016) Stalk-dependent and stalkindependent signaling by the adhesion G protein-coupled receptors GPR56 (ADGRG1) and BAI1 (ADGRB1). J Biol Chem 291:3385-3394
-
(2016)
J Biol Chem
, vol.291
, pp. 3385-3394
-
-
Kishore, A.1
Purcell, R.H.2
Nassiri-Toosi, Z.3
Hall, R.A.4
-
71
-
-
84995438421
-
7TM domain structure of adhesion GPCRs
-
Langenhan T, Schöneberg T (eds), Springer, Heidelberg
-
Nijmeijer S, Wolf S, Ernst OP, de Graaf C (2016) 7TM domain structure of adhesion GPCRs. In: Langenhan T, Schöneberg T (eds) Adhesion G protein-coupled receptors: molecular, physiological and pharmacological principles in health and disease. Springer, Heidelberg
-
(2016)
Adhesion G Protein-Coupled Receptors: Molecular, Physiological and Pharmacological Principles in Health and Disease
-
-
Nijmeijer, S.1
Wolf, S.2
Ernst, O.P.3
de Graaf, C.4
-
72
-
-
84885639028
-
Organ-specific function of adhesion G protein-coupled receptor GPR126 is domain-dependent
-
Patra C, van Amerongen MJ, Ghosh S, Ricciardi F, Sajjad A et al (2013) Organ-specific function of adhesion G protein-coupled receptor GPR126 is domain-dependent. Proc Natl Acad Sci U S A 110:16898-16903
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. 16898-16903
-
-
Patra, C.1
van Amerongen, M.J.2
Ghosh, S.3
Ricciardi, F.4
Sajjad, A.5
-
73
-
-
78649494359
-
The orphan adhesion- GPCR GPR126 is required for embryonic development in the mouse
-
Waller-Evans H, Prömel S, Langenhan T, Dixon J, Zahn D et al (2010) The orphan adhesion- GPCR GPR126 is required for embryonic development in the mouse. PLoS One 5, e14047
-
(2010)
Plos One
, vol.5
-
-
Waller-Evans, H.1
Prömel, S.2
Langenhan, T.3
Dixon, J.4
Zahn, D.5
-
74
-
-
84861315728
-
Activation of myeloid cellspecific adhesion class G protein-coupled receptor EMR2 via ligation-induced translocation and interaction of receptor subunits in lipid raft microdomains
-
Huang YS, Chiang NY, Hu CH, Hsiao CC, Cheng KF et al (2012) Activation of myeloid cellspecific adhesion class G protein-coupled receptor EMR2 via ligation-induced translocation and interaction of receptor subunits in lipid raft microdomains. Mol Cell Biol 32:1408-1420
-
(2012)
Mol Cell Biol
, vol.32
, pp. 1408-1420
-
-
Huang, Y.S.1
Chiang, N.Y.2
Hu, C.H.3
Hsiao, C.C.4
Cheng, K.F.5
-
75
-
-
65249085110
-
Functional crossinteraction of the fragments produced by the cleavage of distinct adhesion G-protein-coupled receptors
-
Silva JP, Lelianova V, Hopkins C, Volynski KE, Ushkaryov Y (2009) Functional crossinteraction of the fragments produced by the cleavage of distinct adhesion G-protein-coupled receptors. J Biol Chem 284:6495-6506
-
(2009)
J Biol Chem
, vol.284
, pp. 6495-6506
-
-
Silva, J.P.1
Lelianova, V.2
Hopkins, C.3
Volynski, K.E.4
Ushkaryov, Y.5
-
76
-
-
79960748416
-
The Latrophilins, “split-personality” receptors
-
Silva JP, Ushkaryov Y (2010) The Latrophilins, “split-personality” receptors. Adv Exp Med Biol 706:59-75
-
(2010)
Adv Exp Med Biol
, vol.706
, pp. 59-75
-
-
Silva, J.P.1
Ushkaryov, Y.2
-
78
-
-
0035019636
-
Proteinase-activated receptors
-
Macfarlane SR, Seatter MJ, Kanke T, Hunter GD, Plevin R (2001) Proteinase-activated receptors. Pharmacol Rev 53:245-282
-
(2001)
Pharmacol Rev
, vol.53
, pp. 245-282
-
-
Macfarlane, S.R.1
Seatter, M.J.2
Kanke, T.3
Hunter, G.D.4
Plevin, R.5
-
79
-
-
0014191175
-
Actions of thrombin and other coagulant and proteolytic enzymes on blood platelets
-
Davey MG, Luscher EF (1967) Actions of thrombin and other coagulant and proteolytic enzymes on blood platelets. Nature 216:857-858
-
(1967)
Nature
, vol.216
, pp. 857-858
-
-
Davey, M.G.1
Luscher, E.F.2
-
80
-
-
0024391784
-
Stimulated secretion of endothelial von Willebrand factor is accompanied by rapid redistribution to the cell surface of the intracellular granule membrane protein GMP-140
-
Hattori R, Hamilton KK, Fugate RD, McEver RP, Sims PJ (1989) Stimulated secretion of endothelial von Willebrand factor is accompanied by rapid redistribution to the cell surface of the intracellular granule membrane protein GMP-140. J Biol Chem 264:7768-7771
-
(1989)
J Biol Chem
, vol.264
, pp. 7768-7771
-
-
Hattori, R.1
Hamilton, K.K.2
Fugate, R.D.3
McEver, R.P.4
Sims, P.J.5
-
81
-
-
0035817822
-
Role of thrombin signalling in platelets in haemostasis and thrombosis
-
Sambrano GR, Weiss EJ, Zheng YW, Huang W, Coughlin SR (2001) Role of thrombin signalling in platelets in haemostasis and thrombosis. Nature 413:74-78
-
(2001)
Nature
, vol.413
, pp. 74-78
-
-
Sambrano, G.R.1
Weiss, E.J.2
Zheng, Y.W.3
Huang, W.4
Coughlin, S.R.5
-
82
-
-
0026035523
-
Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation
-
Vu TK, Hung DT, Wheaton VI, Coughlin SR (1991) Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation. Cell 64:1057-1068
-
(1991)
Cell
, vol.64
, pp. 1057-1068
-
-
Vu, T.K.1
Hung, D.T.2
Wheaton, V.I.3
Coughlin, S.R.4
-
83
-
-
0033596749
-
Protease-activated receptor-1 can mediate responses to SFLLRN in thrombin-desensitized cells: Evidence for a novel mechanism for preventing or terminating signaling by PAR1’s tethered ligand
-
Hammes SR, Coughlin SR (1999) Protease-activated receptor-1 can mediate responses to SFLLRN in thrombin-desensitized cells: evidence for a novel mechanism for preventing or terminating signaling by PAR1’s tethered ligand. Biochemistry 38:2486-2493
-
(1999)
Biochemistry
, vol.38
, pp. 2486-2493
-
-
Hammes, S.R.1
Coughlin, S.R.2
-
84
-
-
0026072517
-
Domains specifying thrombinreceptor interaction
-
Vu TK, Wheaton VI, Hung DT, Charo I, Coughlin SR (1991) Domains specifying thrombinreceptor interaction. Nature 353:674-677
-
(1991)
Nature
, vol.353
, pp. 674-677
-
-
Vu, T.K.1
Wheaton, V.I.2
Hung, D.T.3
Charo, I.4
Coughlin, S.R.5
-
85
-
-
0033613183
-
How the protease thrombin talks to cells
-
Coughlin SR (1999) How the protease thrombin talks to cells. Proc Natl Acad Sci U S A 96:11023-11027
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 11023-11027
-
-
Coughlin, S.R.1
-
86
-
-
0031956683
-
Sol Sherry lecture in thrombosis: How thrombin ‘talks’ to cells: Molecular mechanisms and roles in vivo
-
Coughlin SR (1998) Sol Sherry lecture in thrombosis: how thrombin ‘talks’ to cells: molecular mechanisms and roles in vivo. Arterioscler Thromb Vasc Biol 18:514-518
-
(1998)
Arterioscler Thromb Vasc Biol
, vol.18
, pp. 514-518
-
-
Coughlin, S.R.1
-
87
-
-
84875466697
-
Shear stressdependent downregulation of the adhesion-G protein-coupled receptor CD97 on circulating leukocytes upon contact with its ligand CD 55
-
Karpus ON, Veninga H, Hoek RM, Flierman D, van Buul JD et al (2013) Shear stressdependent downregulation of the adhesion-G protein-coupled receptor CD97 on circulating leukocytes upon contact with its ligand CD 55. J Immunol 190:3740-3748
-
(2013)
J Immunol
, vol.190
, pp. 3740-3748
-
-
Karpus, O.N.1
Veninga, H.2
Hoek, R.M.3
Flierman, D.4
van Buul, J.D.5
-
88
-
-
84939864393
-
Model organisms in G protein-coupled receptor research
-
Langenhan T, Barr MM, Bruchas MR, Ewer J, Griffith LC et al (2015) Model organisms in G protein-coupled receptor research. Mol Pharmacol 88:596-603
-
(2015)
Mol Pharmacol
, vol.88
, pp. 596-603
-
-
Langenhan, T.1
Barr, M.M.2
Bruchas, M.R.3
Ewer, J.4
Griffith, L.C.5
-
89
-
-
84939800716
-
Adhesion G protein-coupled receptors: From in vitro pharmacology to in vivo mechanisms
-
Monk KR, Hamann J, Langenhan T, Nijmeijer S, Schöneberg T et al (2015) Adhesion G protein-coupled receptors: from in vitro pharmacology to in vivo mechanisms. Mol Pharmacol 88:617-623
-
(2015)
Mol Pharmacol
, vol.88
, pp. 617-623
-
-
Monk, K.R.1
Hamann, J.2
Langenhan, T.3
Nijmeijer, S.4
Schöneberg, T.5
-
90
-
-
0027378281
-
Internalization and recycling of activated thrombin receptors
-
Hoxie JA, Ahuja M, Belmonte E, Pizarro S, Parton R et al (1993) Internalization and recycling of activated thrombin receptors. J Biol Chem 268:13756-13763
-
(1993)
J Biol Chem
, vol.268
, pp. 13756-13763
-
-
Hoxie, J.A.1
Ahuja, M.2
Belmonte, E.3
Pizarro, S.4
Parton, R.5
-
91
-
-
0032506111
-
Termination of signaling by protease-activated receptor-1 is linked to lysosomal sorting
-
Trejo J, Hammes SR, Coughlin SR (1998) Termination of signaling by protease-activated receptor-1 is linked to lysosomal sorting. Proc Natl Acad Sci U S A 95:13698-13702
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 13698-13702
-
-
Trejo, J.1
Hammes, S.R.2
Coughlin, S.R.3
-
92
-
-
1442358746
-
Distinct roles for ADAM10 and ADAM17 in ectodomain shedding of six EGFR ligands
-
Sahin U, Weskamp G, Kelly K, Zhou HM, Higashiyama S et al (2004) Distinct roles for ADAM10 and ADAM17 in ectodomain shedding of six EGFR ligands. J Cell Biol 164:769-779
-
(2004)
J Cell Biol
, vol.164
, pp. 769-779
-
-
Sahin, U.1
Weskamp, G.2
Kelly, K.3
Zhou, H.M.4
Higashiyama, S.5
-
94
-
-
8044257704
-
A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells
-
Black RA, Rauch CT, Kozlosky CJ, Peschon JJ, Slack JL et al (1997) A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells. Nature 385:729-733
-
(1997)
Nature
, vol.385
, pp. 729-733
-
-
Black, R.A.1
Rauch, C.T.2
Kozlosky, C.J.3
Peschon, J.J.4
Slack, J.L.5
-
95
-
-
0024281428
-
A novel form of Tnf/cachectin is a cellsurface cyto-toxic transmembrane protein - Ramifications for the complex physiology of Tnf
-
Kriegler M, Perez C, Defay K, Albert I, Lu SD (1988) A novel form of Tnf/cachectin is a cellsurface cyto-toxic transmembrane protein - ramifications for the complex physiology of Tnf. Cell 53:45-53
-
(1988)
Cell
, vol.53
, pp. 45-53
-
-
Kriegler, M.1
Perez, C.2
Defay, K.3
Albert, I.4
Lu, S.D.5
-
96
-
-
0037474447
-
Putative function of ADAM9, ADAM10, and ADAM17 as APP-secretase
-
Asai M, Hattori C, Szabo´ B, Sasagawa N, Maruyama K et al (2003) Putative function of ADAM9, ADAM10, and ADAM17 as APP-secretase. Biochem Biophys Res Commun 301:231-235
-
(2003)
Biochem Biophys Res Commun
, vol.301
, pp. 231-235
-
-
Asai, M.1
Hattori, C.2
Szabo´, B.3
Sasagawa, N.4
Maruyama, K.5
-
97
-
-
85047690140
-
A disintegrinmetalloproteinase prevents amyloid plaque formation and hippocampal defects in an Alzheimer disease mouse model
-
Postina R, Schroeder A, Dewachter I, Bohl J, Schmitt U et al (2004) A disintegrinmetalloproteinase prevents amyloid plaque formation and hippocampal defects in an Alzheimer disease mouse model. J Clin Invest 113:1456-1464
-
(2004)
J Clin Invest
, vol.113
, pp. 1456-1464
-
-
Postina, R.1
Schroeder, A.2
Dewachter, I.3
Bohl, J.4
Schmitt, U.5
-
98
-
-
0025753852
-
The molecular pathology of Alzheimer’s disease
-
Selkoe DJ (1991) The molecular pathology of Alzheimer’s disease. Neuron 6:487-498
-
(1991)
Neuron
, vol.6
, pp. 487-498
-
-
Selkoe, D.J.1
-
99
-
-
0033595706
-
Beta-secretase cleavage of Alzheimer’s amyloid precursor protein by the transmembrane aspartic protease BACE
-
Vassar R, Bennett BD, Babu-Khan S, Kahn S, Mendiaz EA et al (1999) Beta-secretase cleavage of Alzheimer’s amyloid precursor protein by the transmembrane aspartic protease BACE. Science 286:735-741
-
(1999)
Science
, vol.286
, pp. 735-741
-
-
Vassar, R.1
Bennett, B.D.2
Babu-Khan, S.3
Kahn, S.4
Mendiaz, E.A.5
-
100
-
-
0029085935
-
Signalling downstream of activated mammalian Notch
-
Jarriault S, Brou C, Logeat F, Schroeter EH, Kopan R et al (1995) Signalling downstream of activated mammalian Notch. Nature 377:355-358
-
(1995)
Nature
, vol.377
, pp. 355-358
-
-
Jarriault, S.1
Brou, C.2
Logeat, F.3
Schroeter, E.H.4
Kopan, R.5
-
101
-
-
0033021954
-
Notch signalling pathway mediates hair cell development in mammalian cochlea
-
Lanford PJ, Lan Y, Jiang RL, Lindsell C, Weinmaster G et al (1999) Notch signalling pathway mediates hair cell development in mammalian cochlea. Nat Genet 21:289-292
-
(1999)
Nat Genet
, vol.21
, pp. 289-292
-
-
Lanford, P.J.1
Lan, Y.2
Jiang, R.L.3
Lindsell, C.4
Weinmaster, G.5
-
102
-
-
0033606972
-
Notch signalling controls pancreatic cell differentiation
-
Apelqvist A, Li H, Sommer L, Beatus P, Anderson DJ et al (1999) Notch signalling controls pancreatic cell differentiation. Nature 400:877-881
-
(1999)
Nature
, vol.400
, pp. 877-881
-
-
Apelqvist, A.1
Li, H.2
Sommer, L.3
Beatus, P.4
Erson, D.J.5
-
103
-
-
20544460148
-
Notch/gammasecretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells
-
van Es JH, van Gijn ME, Riccio O, van den Born M, Vooijs M et al (2005) Notch/gammasecretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells. Nature 435:959-963
-
(2005)
Nature
, vol.435
, pp. 959-963
-
-
van Es, J.H.1
van Gijn, M.E.2
Riccio, O.3
van Den Born, M.4
Vooijs, M.5
-
104
-
-
0031001247
-
Notch activity influences the alphabeta versus gammadelta T cell lineage decision
-
Washburn T, Schweighoffer E, Gridley T, Chang D, Fowlkes BJ et al (1997) Notch activity influences the alphabeta versus gammadelta T cell lineage decision. Cell 88:833-843
-
(1997)
Cell
, vol.88
, pp. 833-843
-
-
Washburn, T.1
Schweighoffer, E.2
Gridley, T.3
Chang, D.4
Fowlkes, B.J.5
-
105
-
-
0030297895
-
An activated form of notch influences the choice between CD4 and CD8 T cell lineages
-
Robey E, Chang D, Itano A, Cado D, Alexander H et al (1996) An activated form of notch influences the choice between CD4 and CD8 T cell lineages. Cell 87:483-492
-
(1996)
Cell
, vol.87
, pp. 483-492
-
-
Robey, E.1
Chang, D.2
Itano, A.3
Cado, D.4
Alexander, H.5
-
106
-
-
15444371289
-
ADAM10 cleavage of N-cadherin and regulation of cell-cell adhesion and beta-catenin nuclear signalling
-
Reiss K, Maretzky T, Ludwig A, Tousseyn T, de Strooper B et al (2005) ADAM10 cleavage of N-cadherin and regulation of cell-cell adhesion and beta-catenin nuclear signalling. EMBO J 24:742-752
-
(2005)
EMBO J
, vol.24
, pp. 742-752
-
-
Reiss, K.1
Maretzky, T.2
Ludwig, A.3
Tousseyn, T.4
de Strooper, B.5
-
107
-
-
33744899335
-
Characterization of sequential N-cadherin cleavage by ADAM10 and PS 1
-
Uemura K, Kihara T, Kuzuya A, Okawa K, Nishimoto T et al (2006) Characterization of sequential N-cadherin cleavage by ADAM10 and PS 1. Neurosci Lett 402:278-283
-
(2006)
Neurosci Lett
, vol.402
, pp. 278-283
-
-
Uemura, K.1
Kihara, T.2
Kuzuya, A.3
Okawa, K.4
Nishimoto, T.5
-
108
-
-
0034714357
-
Regulated cleavage of a contact-mediated axon repellent
-
Hattori M, Osterfield M, Flanagan JG (2000) Regulated cleavage of a contact-mediated axon repellent. Science 289:1360-1365
-
(2000)
Science
, vol.289
, pp. 1360-1365
-
-
Hattori, M.1
Osterfield, M.2
Flanagan, J.G.3
-
109
-
-
84947484060
-
The alpha secretase ADAM10: A metalloprotease with multiple functions in the brain
-
Saftig P, Lichtenthaler SF (2015) The alpha secretase ADAM10: a metalloprotease with multiple functions in the brain. Prog Neurobiol 135:1-20
-
(2015)
Prog Neurobiol
, vol.135
, pp. 1-20
-
-
Saftig, P.1
Lichtenthaler, S.F.2
-
110
-
-
84867722362
-
Activity-dependent proteolytic cleavage of neuroligin-1
-
Suzuki K, Hayashi Y, Nakahara S, Kumazaki H, Prox J et al (2012) Activity-dependent proteolytic cleavage of neuroligin-1. Neuron 76:410-422
-
(2012)
Neuron
, vol.76
, pp. 410-422
-
-
Suzuki, K.1
Hayashi, Y.2
Nakahara, S.3
Kumazaki, H.4
Prox, J.5
-
111
-
-
78951488794
-
Processing of the synaptic cell adhesion molecule neurexin-3beta by Alzheimer disease alpha- and gamma-secretases
-
Bot N, Schweizer C, Ben Halima S, Fraering PC (2011) Processing of the synaptic cell adhesion molecule neurexin-3beta by Alzheimer disease alpha- and gamma-secretases. J Biol Chem 286:2762-2773
-
(2011)
J Biol Chem
, vol.286
, pp. 2762-2773
-
-
Bot, N.1
Schweizer, C.2
Ben Halima, S.3
Fraering, P.C.4
-
112
-
-
79955761820
-
Presenilin/gamma-secretase regulates neurexin processing at synapses
-
Saura CA, Servian-Morilla E, Scholl FG (2011) Presenilin/gamma-secretase regulates neurexin processing at synapses. PLoS One 6, e19430
-
(2011)
Plos One
, vol.6
-
-
Saura, C.A.1
Servian-Morilla, E.2
Scholl, F.G.3
-
113
-
-
0034648757
-
Thrombin signalling and protease-activated receptors
-
Coughlin SR (2000) Thrombin signalling and protease-activated receptors. Nature 407:258-264
-
(2000)
Nature
, vol.407
, pp. 258-264
-
-
Coughlin, S.R.1
-
114
-
-
0025277746
-
Molecular interactions between the protein products of the neurogenic loci Notch and Delta, two EGF-homologous genes in Drosophila
-
Fehon RG, Kooh PJ, Rebay I, Regan CL, Xu T et al (1990) Molecular interactions between the protein products of the neurogenic loci Notch and Delta, two EGF-homologous genes in Drosophila. Cell 61:523-534
-
(1990)
Cell
, vol.61
, pp. 523-534
-
-
Fehon, R.G.1
Kooh, P.J.2
Rebay, I.3
Regan, C.L.4
Xu, T.5
-
115
-
-
0026086474
-
Specific EGF repeats of Notch mediate interactions with Delta and Serrate: Implications for Notch as a multifunctional receptor
-
Rebay I, Fleming RJ, Fehon RG, Cherbas L, Cherbas P et al (1991) Specific EGF repeats of Notch mediate interactions with Delta and Serrate: implications for Notch as a multifunctional receptor. Cell 67:687-699
-
(1991)
Cell
, vol.67
, pp. 687-699
-
-
Rebay, I.1
Fleming, R.J.2
Fehon, R.G.3
Cherbas, L.4
Cherbas, P.5
-
116
-
-
0029787130
-
The seven-span transmembrane receptor CD97 has a cellular ligand (CD55, DAF)
-
Hamann J, Vogel B, van Schijndel GM, van Lier RA (1996) The seven-span transmembrane receptor CD97 has a cellular ligand (CD55, DAF). J Exp Med 184:1185-1189
-
(1996)
J Exp Med
, vol.184
, pp. 1185-1189
-
-
Hamann, J.1
Vogel, B.2
van Schijndel, G.M.3
van Lier, R.A.4
-
117
-
-
84858597379
-
High affinity neurexin binding to cell adhesion Gprotein- coupled receptor CIRL1/latrophilin-1 produces an intercellular adhesion complex
-
Boucard AA, Ko J, Südhof TC (2012) High affinity neurexin binding to cell adhesion Gprotein- coupled receptor CIRL1/latrophilin-1 produces an intercellular adhesion complex. J Biol Chem 287:9399-9413
-
(2012)
J Biol Chem
, vol.287
, pp. 9399-9413
-
-
Boucard, A.A.1
Ko, J.2
Südhof, T.C.3
-
118
-
-
84858027355
-
FLRT proteins are endogenous latrophilin ligands and regulate excitatory synapse development
-
O’Sullivan ML, de Wit J, Savas JN, Comoletti D, Otto-Hitt S et al (2012) FLRT proteins are endogenous latrophilin ligands and regulate excitatory synapse development. Neuron 73:903-910
-
(2012)
Neuron
, vol.73
, pp. 903-910
-
-
O’Sullivan, M.L.1
de Wit, J.2
Savas, J.N.3
Comoletti, D.4
Otto-Hitt, S.5
-
119
-
-
79961071808
-
Latrophilin 1 and its endogenous ligand Lasso/teneurin-2 form a high-affinity transsynaptic receptor pair with signaling capabilities
-
Silva JP, Lelianova VG, Ermolyuk YS, Vysokov N, Hitchen PG et al (2011) Latrophilin 1 and its endogenous ligand Lasso/teneurin-2 form a high-affinity transsynaptic receptor pair with signaling capabilities. Proc Natl Acad Sci U S A 108:12113-12118
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 12113-12118
-
-
Silva, J.P.1
Lelianova, V.G.2
Ermolyuk, Y.S.3
Vysokov, N.4
Hitchen, P.G.5
-
120
-
-
33747623018
-
Notch signalling: A simple pathway becomes complex
-
Bray SJ (2006) Notch signalling: a simple pathway becomes complex. Nat Rev Mol Cell Biol 7:678-689
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, pp. 678-689
-
-
Bray, S.J.1
-
121
-
-
0025971830
-
The choice of cell fate in the epidermis of Drosophila
-
Heitzler P, Simpson P (1991) The choice of cell fate in the epidermis of Drosophila. Cell 64:1083-1092
-
(1991)
Cell
, vol.64
, pp. 1083-1092
-
-
Heitzler, P.1
Simpson, P.2
-
122
-
-
70350439585
-
Notch activity in the nervous system: To switch or not switch?
-
Cau E, Blader P (2009) Notch activity in the nervous system: to switch or not switch? Neural Dev 4:36
-
(2009)
Neural Dev
, vol.4
, pp. 36
-
-
Cau, E.1
Blader, P.2
-
123
-
-
0030877659
-
Intracellular cleavage of Notch leads to a heterodimeric receptor on the plasma membrane
-
Blaumueller CM, Qi H, Zagouras P, Artavanis-Tsakonas S (1997) Intracellular cleavage of Notch leads to a heterodimeric receptor on the plasma membrane. Cell 90:281-291
-
(1997)
Cell
, vol.90
, pp. 281-291
-
-
Blaumueller, C.M.1
Qi, H.2
Zagouras, P.3
Artavanis-Tsakonas, S.4
-
124
-
-
0032493302
-
The Notch1 receptor is cleaved constitutively by a furin-like convertase
-
Logeat F, Bessia C, Brou C, LeBail O, Jarriault S et al (1998) The Notch1 receptor is cleaved constitutively by a furin-like convertase. Proc Natl Acad Sci U S A 95:8108-8112
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 8108-8112
-
-
Logeat, F.1
Bessia, C.2
Brou, C.3
Lebail, O.4
Jarriault, S.5
-
125
-
-
0037210999
-
HE6, a two-subunit heptahelical receptor associated with apical membranes of efferent and epididymal duct epithelia
-
Obermann H, Samalecos A, Osterhoff C, Schroder B, Heller R et al (2003) HE6, a two-subunit heptahelical receptor associated with apical membranes of efferent and epididymal duct epithelia. Mol Reprod Dev 64:13-26
-
(2003)
Mol Reprod Dev
, vol.64
, pp. 13-26
-
-
Obermann, H.1
Samalecos, A.2
Osterhoff, C.3
Schroder, B.4
Heller, R.5
-
126
-
-
0033868818
-
A novel proteolytic cleavage involved in Notch signaling: The role of the disintegrin-metalloprotease TACE
-
Brou C, Logeat F, Gupta N, Bessia C, LeBail O et al (2000) A novel proteolytic cleavage involved in Notch signaling: the role of the disintegrin-metalloprotease TACE. Mol Cell 5:207-216
-
(2000)
Mol Cell
, vol.5
, pp. 207-216
-
-
Brou, C.1
Logeat, F.2
Gupta, N.3
Bessia, C.4
Lebail, O.5
-
127
-
-
0033867521
-
A ligand-induced extracellular cleavage regulates gamma-secretase-like proteolytic activation of Notch 1
-
Mumm JS, Schroeter EH, Saxena MT, Griesemer A, Tian X et al (2000) A ligand-induced extracellular cleavage regulates gamma-secretase-like proteolytic activation of Notch 1. Mol Cell 5:197-206
-
(2000)
Mol Cell
, vol.5
, pp. 197-206
-
-
Mumm, J.S.1
Schroeter, E.H.2
Saxena, M.T.3
Griesemer, A.4
Tian, X.5
-
128
-
-
0034051852
-
Ligand endocytosis drives receptor dissociation and activation in the Notch pathway
-
Parks AL, Klueg KM, Stout JR, Muskavitch MA (2000) Ligand endocytosis drives receptor dissociation and activation in the Notch pathway. Development 127:1373-1385
-
(2000)
Development
, vol.127
, pp. 1373-1385
-
-
Parks, A.L.1
Klueg, K.M.2
Stout, J.R.3
Muskavitch, M.A.4
-
129
-
-
84867381846
-
Direct observation of proteolytic cleavage at the S2 site upon forced unfolding of the Notch negative regulatory region
-
Stephenson NL, Avis JM (2012) Direct observation of proteolytic cleavage at the S2 site upon forced unfolding of the Notch negative regulatory region. Proc Natl Acad Sci U S A 109: E2757-E2765
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. E2757-E2765
-
-
Stephenson, N.L.1
Avis, J.M.2
-
130
-
-
0036273316
-
Furin cleavage is not a requirement for Drosophila Notch function
-
Kidd S, Lieber T (2002) Furin cleavage is not a requirement for Drosophila Notch function. Mech Dev 115:41-51
-
(2002)
Mech Dev
, vol.115
, pp. 41-51
-
-
Kidd, S.1
Lieber, T.2
-
131
-
-
18644367748
-
Presenilins mediate a dual intramembranous gamma-secretase cleavage of Notch-1
-
Okochi M, Steiner H, Fukumori A, Tanii H, Tomita T et al (2002) Presenilins mediate a dual intramembranous gamma-secretase cleavage of Notch-1. EMBO J 21:5408-5416
-
(2002)
EMBO J
, vol.21
, pp. 5408-5416
-
-
Okochi, M.1
Steiner, H.2
Fukumori, A.3
Tanii, H.4
Tomita, T.5
-
132
-
-
0033639117
-
Requirements for presenilin-dependent cleavage of notch and other transmembrane proteins
-
Struhl G, Adachi A (2000) Requirements for presenilin-dependent cleavage of notch and other transmembrane proteins. Mol Cell 6:625-636
-
(2000)
Mol Cell
, vol.6
, pp. 625-636
-
-
Struhl, G.1
Adachi, A.2
-
133
-
-
0032417174
-
Ligand-induced cleavage and regulation of nuclear entry of Notch in Drosophila melanogaster embryos
-
Kidd S, Lieber T, Young MW (1998) Ligand-induced cleavage and regulation of nuclear entry of Notch in Drosophila melanogaster embryos. Genes Dev 12:3728-3740
-
(1998)
Genes Dev
, vol.12
, pp. 3728-3740
-
-
Kidd, S.1
Lieber, T.2
Young, M.W.3
-
134
-
-
0032543565
-
Indirect evidence for delta-dependent intracellular processing of notch in Drosophila embryos
-
Lecourtois M, Schweisguth F (1998) Indirect evidence for delta-dependent intracellular processing of notch in Drosophila embryos. Curr Biol 8:771-774
-
(1998)
Curr Biol
, vol.8
, pp. 771-774
-
-
Lecourtois, M.1
Schweisguth, F.2
-
135
-
-
0032574993
-
Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain
-
Schroeter EH, Kisslinger JA, Kopan R (1998) Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain. Nature 393:382-386
-
(1998)
Nature
, vol.393
, pp. 382-386
-
-
Schroeter, E.H.1
Kisslinger, J.A.2
Kopan, R.3
-
136
-
-
0032524325
-
Nuclear access and action of notch in vivo
-
Struhl G, Adachi A (1998) Nuclear access and action of notch in vivo. Cell 93:649-660
-
(1998)
Cell
, vol.93
, pp. 649-660
-
-
Struhl, G.1
Adachi, A.2
-
137
-
-
26844448800
-
Adam meets Eph: An ADAM substrate recognition module acts as a molecular switch for ephrin cleavage in trans
-
Janes PW, Saha N, Barton WA, Kolev MV, Wimmer-Kleikamp SH et al (2005) Adam meets Eph: an ADAM substrate recognition module acts as a molecular switch for ephrin cleavage in trans. Cell 123:291-304
-
(2005)
Cell
, vol.123
, pp. 291-304
-
-
Janes, P.W.1
Saha, N.2
Barton, W.A.3
Kolev, M.V.4
Wimmer-Kleikamp, S.H.5
-
138
-
-
26844556313
-
ADAM and Eph: How Ephrin-signaling cells become detached
-
Mancia F, Shapiro L (2005) ADAM and Eph: how Ephrin-signaling cells become detached. Cell 123:185-187
-
(2005)
Cell
, vol.123
, pp. 185-187
-
-
Mancia, F.1
Shapiro, L.2
-
139
-
-
0031922119
-
The ephrins and Eph receptors in neural development
-
Flanagan JG, Vanderhaeghen P (1998) The ephrins and Eph receptors in neural development. Annu Rev Neurosci 21:309-345
-
(1998)
Annu Rev Neurosci
, vol.21
, pp. 309-345
-
-
Flanagan, J.G.1
Vanderhaeghen, P.2
-
140
-
-
84875602708
-
Antibodies binding the ADAM10 substrate recognition domain inhibit Eph function
-
Atapattu L, Saha N, Llerena C, Vail ME, Scott AM et al (2012) Antibodies binding the ADAM10 substrate recognition domain inhibit Eph function. J Cell Sci 125:6084-6093
-
(2012)
J Cell Sci
, vol.125
, pp. 6084-6093
-
-
Atapattu, L.1
Saha, N.2
Llerena, C.3
Vail, M.E.4
Scott, A.M.5
-
141
-
-
0036303033
-
Mechanisms and functions of Eph and ephrin signalling
-
Kullander K, Klein R (2002) Mechanisms and functions of Eph and ephrin signalling. Nat Rev Mol Cell Biol 3:475-486
-
(2002)
Nat Rev Mol Cell Biol
, vol.3
, pp. 475-486
-
-
Kullander, K.1
Klein, R.2
-
142
-
-
84935137467
-
Eph/ ephrins-mediated thymocyte-thymic epithelial cell interactions control numerous processes of thymus biology
-
Garcia-Ceca J, Alfaro D, Montero-Herradoń S, Tobajas E, Munoz JJ et al (2015) Eph/ ephrins-mediated thymocyte-thymic epithelial cell interactions control numerous processes of thymus biology. Front Immunol 6:333
-
(2015)
Front Immunol
, vol.6
, pp. 333
-
-
Garcia-Ceca, J.1
Alfaro, D.2
Montero-Herradoń, S.3
Tobajas, E.4
Munoz, J.J.5
-
143
-
-
84919883546
-
Eph receptor and ephrin function in breast, gut, and skin epithelia
-
Perez White BE, Getsios S (2014) Eph receptor and ephrin function in breast, gut, and skin epithelia. Cell Adh Migr 8:327-338
-
(2014)
Cell Adh Migr
, vol.8
, pp. 327-338
-
-
Perez White, B.E.1
Getsios, S.2
-
145
-
-
77949412667
-
Restriction of receptor movement alters cellular response: Physical force sensing by EphA 2
-
Salaita K, Nair PM, Petit RS, Neve RM, Das D et al (2010) Restriction of receptor movement alters cellular response: physical force sensing by EphA 2. Science 327:1380-1385
-
(2010)
Science
, vol.327
, pp. 1380-1385
-
-
Salaita, K.1
Nair, P.M.2
Petit, R.S.3
Neve, R.M.4
Das, D.5
-
146
-
-
70350503425
-
Cytoplasmic relaxation of active Eph controls ephrin shedding by ADAM 10
-
Janes PW, Wimmer-Kleikamp SH, Frangakis AS, Treble K, Griesshaber B et al (2009) Cytoplasmic relaxation of active Eph controls ephrin shedding by ADAM 10. PLoS Biol 7, e1000215
-
(2009)
Plos Biol
, vol.7
-
-
Janes, P.W.1
Wimmer-Kleikamp, S.H.2
Frangakis, A.S.3
Treble, K.4
Griesshaber, B.5
-
147
-
-
0035929146
-
Structural basis for autoinhibition of the Ephb2 receptor tyrosine kinase by the unphosphorylated juxtamembrane region
-
Wybenga-Groot LE, Baskin B, Ong SH, Tong J, Pawson T et al (2001) Structural basis for autoinhibition of the Ephb2 receptor tyrosine kinase by the unphosphorylated juxtamembrane region. Cell 106:745-757
-
(2001)
Cell
, vol.106
, pp. 745-757
-
-
Wybenga-Groot, L.E.1
Baskin, B.2
Ong, S.H.3
Tong, J.4
Pawson, T.5
-
148
-
-
84862854305
-
Eph-dependent cell-cell adhesion and segregation in development and cancer
-
Nievergall E, Lackmann M, Janes PW (2012) Eph-dependent cell-cell adhesion and segregation in development and cancer. Cell Mol Life Sci 69:1813-1842
-
(2012)
Cell Mol Life Sci
, vol.69
, pp. 1813-1842
-
-
Nievergall, E.1
Lackmann, M.2
Janes, P.W.3
-
149
-
-
84918804823
-
The role of proteases in regulating Eph/ephrin signaling
-
Atapattu L, Lackmann M, Janes PW (2014) The role of proteases in regulating Eph/ephrin signaling. Cell Adh Migr 8:294-307
-
(2014)
Cell Adh Migr
, vol.8
, pp. 294-307
-
-
Atapattu, L.1
Lackmann, M.2
Janes, P.W.3
-
150
-
-
0029069583
-
The polycystic kidney disease 1 (PKD1) gene encodes a novel protein with multiple cell recognition domains
-
Hughes J, Ward CJ, Peral B, Aspinwall R, Clark K et al (1995) The polycystic kidney disease 1 (PKD1) gene encodes a novel protein with multiple cell recognition domains. Nat Genet 10:151-160
-
(1995)
Nat Genet
, vol.10
, pp. 151-160
-
-
Hughes, J.1
Ward, C.J.2
Peral, B.3
Aspinwall, R.4
Clark, K.5
-
151
-
-
0036707893
-
Genetics and pathogenesis of polycystic kidney disease
-
Igarashi P, Somlo S (2002) Genetics and pathogenesis of polycystic kidney disease. J Am Soc Nephrol 13:2384-2398
-
(2002)
J am Soc Nephrol
, vol.13
, pp. 2384-2398
-
-
Igarashi, P.1
Somlo, S.2
-
152
-
-
0021680149
-
Autosomal dominant polycystic kidney disease: Symptoms and clinical findings
-
Milutinovic J, Fialkow PJ, Agodoa LY, Phillips LA, Rudd TG et al (1984) Autosomal dominant polycystic kidney disease: symptoms and clinical findings. Q J Med 53:511-522
-
(1984)
Q J Med
, vol.53
, pp. 511-522
-
-
Milutinovic, J.1
Fialkow, P.J.2
Agodoa, L.Y.3
Phillips, L.A.4
Rudd, T.G.5
-
153
-
-
0037868262
-
Functional analysis of PKD1 transgenic lines reveals a direct role for polycystin-1 in mediating cell-cell adhesion
-
Streets AJ, Newby LJ, O’Hare MJ, Bukanov NO, Ibraghimov-Beskrovnaya O et al (2003) Functional analysis of PKD1 transgenic lines reveals a direct role for polycystin-1 in mediating cell-cell adhesion. J Am Soc Nephrol 14:1804-1815
-
(2003)
J am Soc Nephrol
, vol.14
, pp. 1804-1815
-
-
Streets, A.J.1
Newby, L.J.2
O’Hare, M.J.3
Bukanov, N.O.4
Ibraghimov-Beskrovnaya, O.5
-
154
-
-
67650544382
-
Homophilic and heterophilic polycystin 1 interactions regulate E-cadherin recruitment and junction assembly in MDCK cells
-
Streets AJ, Wagner BE, Harris PC, Ward CJ, Ong AC (2009) Homophilic and heterophilic polycystin 1 interactions regulate E-cadherin recruitment and junction assembly in MDCK cells. J Cell Sci 122:1410-1417
-
(2009)
J Cell Sci
, vol.122
, pp. 1410-1417
-
-
Streets, A.J.1
Wagner, B.E.2
Harris, P.C.3
Ward, C.J.4
Ong, A.C.5
-
155
-
-
84942983407
-
A polycystin-centric view of cyst formation and disease: The polycystins revisited
-
Ong AC, Harris PC (2015) A polycystin-centric view of cyst formation and disease: the polycystins revisited. Kidney Int 88:699-710
-
(2015)
Kidney Int
, vol.88
, pp. 699-710
-
-
Ong, A.C.1
Harris, P.C.2
-
156
-
-
0031252295
-
Perinatal lethality with kidney and pancreas defects in mice with a targetted Pkd1 mutation
-
Lu W, Peissel B, Babakhanlou H, Pavlova A, Geng L et al (1997) Perinatal lethality with kidney and pancreas defects in mice with a targetted Pkd1 mutation. Nat Genet 17:179-181
-
(1997)
Nat Genet
, vol.17
, pp. 179-181
-
-
Lu, W.1
Peissel, B.2
Babakhanlou, H.3
Pavlova, A.4
Geng, L.5
-
157
-
-
29744470060
-
Polycystin-1, STAT6, and P100 function in a pathway that transduces ciliary mechanosensation and is activated in polycystic kidney disease
-
Low SH, Vasanth S, Larson CH, Mukherjee S, Sharma N et al (2006) Polycystin-1, STAT6, and P100 function in a pathway that transduces ciliary mechanosensation and is activated in polycystic kidney disease. Dev Cell 10:57-69
-
(2006)
Dev Cell
, vol.10
, pp. 57-69
-
-
Low, S.H.1
Vasanth, S.2
Larson, C.H.3
Mukherjee, S.4
Sharma, N.5
-
158
-
-
84855952173
-
The gamma-secretase cleavage product of polycystin-1 regulates TCF and CHOP-mediated transcriptional activation through a p300-dependent mechanism
-
Merrick D, Chapin H, Baggs JE, Yu Z, Somlo S et al (2012) The gamma-secretase cleavage product of polycystin-1 regulates TCF and CHOP-mediated transcriptional activation through a p300-dependent mechanism. Dev Cell 22:197-210
-
(2012)
Dev Cell
, vol.22
, pp. 197-210
-
-
Merrick, D.1
Chapin, H.2
Baggs, J.E.3
Yu, Z.4
Somlo, S.5
|