An activated form of Notch influences the choice between CD4 and CD8 T cell lineages

Cell

Volumn 87, Issue 3, 1996, Pages 483-492

  Robey, Ellen ^a   Chang, David ^a   Itano, Andrea ^a   Cado, Dragana ^a   Alexander, Heather ^a   Lans, Deborah ^a   Weinmaster, Gerry ^b   Salmon, Patrick ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; LIGAND; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MEMBRANE RECEPTOR;

ANIMAL CELL; ARTICLE; CELL MATURATION; CONTROLLED STUDY; GENE ACTIVATION; LIGAND BINDING; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTOPOIESIS; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; T LYMPHOCYTE SUBPOPULATION; THYMOCYTE; TRANSGENIC MOUSE;

ANIMALIA; MAMMALIA; MUS MUSCULUS;

EID: 0030297895     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(00)81368-9     Document Type: Article

References (50)

1. Abraham, K., Levin, S., Marth, J., Forbush, K., and Perlmutter, R. (1991). Thymic tumorigenesis induced by overexpression of p56lck. Proc. Natl. Acad. Sci. USA 88, 3977-3981.
2. Artavanis-Tsakonas, S., Matsuno, K., and Fortini, M. (1995). Notch signaling. Science 268, 225-232.
3. Austin, C., Feldman, D., Ida, J., and Cepko, C. (1995). Vertebrate retinal ganglion cells are selected from competent progenitors by the action of Notch. Development 121, 3637-3650.
4. Beitel, G., Tuck, S., Greenwald, I., and Horvitz, H. (1995). The C. elegans gene lin-1 encodes an ETS-domain protein and defines a branch of the vulval induction pathway. Genes Dev. (in press).
5. Bettenhausen, B., Hrabe de Angelis, M., Simon, D., Guenet, J.-L., and Gossler, A. (1995). Transient and restricted expression during mouse embryogenesis of DII1, a murine gene closely related to Drosophila Delta. Development 121, 2407-2418.
6. Bix, M., and Raulet, D. (1992). Inefficient positive selection of T-cells directed by hematopoietic cells. Nature 359, 330.
7. Chaffin, K.E., Beals, C.R., Wilkie, T.M., Forbush, K.A., Simon, M.I., and Perlmutter, R.M. (1990). Dissection of thymocyte signaling pathways by in vivo expression of pertussis toxin ADP-ribosyltransferase. EMBO J. 9, 3821-3829.
8. Chitnis, A., Henrique, D., Lewis, J., Ish-Horowicz, D., and Kintner, C. (1995). Primary neurogenesis in Xenopus embryos regulated by a homologue of the Drosophila neurogenic gene Delta. Nature 375, 761-766.
9. Coffman, C., Harris, W., and Kintner, C. (1990). Xotch, the Xenopus homolog of Drosophila notch. Science 249, 1438-1441.
10. Coffman, C., Skoglund, P., Harris, W., and Kintner, C. (1993). Expression of an extracellular deletion of Xotch diverts cell fate in Xenopus embryos. Cell 73, 659-671.
11. Conlon, R., Reaume, A., and Rossant, J. (1995). Notch1 is required for the coordinate segmentation of somites. Development 121, 1533-1545.
12. Cosgrove, D., Gray, D., Dierich, A., Kaufman, J., Lemeur, M., Benoist, C., and Mathis, D. (1991). Mice lacking MHC class II molecules. Cell 66, 1051-1066.
13. del Amo, F., Smith, D., Swiatek, P., Gendron-Maguire, M., Greenspan, R., McMahon, A., and Gridley, T. (1992). Expression pattern of Motch, a mouse homolog of Drosophila Notch, suggests an important role in early postimplantation mouse development. Development 115, 737-744.
14. del Amo, F., Gendron-Maguire, M., Swiatek, P., Jenkins, N., Copeland, N., and Gridley, T. (1993). Cloning, analysis, and chromosomal localization of Notch-1, a mouse homolog of Drosophila Notch. Genomics 15, 259-264.
15. Diaz-Benjumea, F., and Cohen, S.M. (1995). Serrate signals through Notch to establish a Wingless-dependent organizer at the dorsal/ ventral compartment boundary of the Drosophila wing. Development 121, 4215-4255.
16. Egerton, M., Scollay, R., and Shortman, K. (1990). Kinetics of mature T-cell development in the thymus. Proc. Natl. Acad. Sci. USA 87, 2579-2582.
17. Ellisen, L.W., Bird, J., West, D.C., Soreng, A.L., Reynolds, T.C., Smith, S.D., and Sklar, J. (1991). TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms. Cell 66, 649-661.
18. Greenwald, I., and Rubin, G. (1992). Making a difference: the role of cell-cell interactions in establishing separate identities for equivalent cells. Cell 68, 271-281.
19. Grusby, M.J., Johnson, R.S., Papaioannou, V.E., and Glimcher, L.H. (1991). Depletion of CD4+ T cells in major histocompatibility complex class II-deficient mice. Science 253, 1417-1420.
20. Hasserjian, R., Aster, J., Davi, D., Weinberg, D., and Sklar, J. (1996). Modulated expression of Notch1 during thymocyte development. Blood 88, 970-976.
21. Heitzler, P., and Simpson, P. (1991). The choice of cell fate in the epidermis of Drosophila. Cell 64, 1083-1092.
22. Henderson (1994). lag-2 may encode a signaling ligand for the GLP-1 and LIN-12 receptors of C. elegans. Development 120, 2913-2924.
23. Henrique, D., Adam, J., Myat, A., Chitnis, A., Lewis, J., and Ish-Horowicz, D. (1995). Expression of a Delta homologue in prospective neurons in the chick. Nature 375, 787-790.
24. Itano, A., Salmon, P., Kioussis, D., Tolaini, M., Corbella, P., and Robey, E. (1996). The cytoplasmic domain of CD4 promotes the development of CD4 lineage T cells. J. Exp. Med. 183, 731-741.
25. Jameson, S.C., Hogquist, K.A., and Bevan, M.J. (1995). Positive selection of thymocytes. Annu. Rev. Immunol. 13, 93-126.
26. Jhappan, C., Gallahan, D., Stahle, C., Chu, E., Smith, G., Merlino, G., and Callahan, R. (1992). Expression of an activated Notch-related int-3 transgene interferes with cell differentiation and induces neoplastic transformation in mammary and salavary glands. Genes Dev. 6, 345-355.
27. Katz, W., Hill, R., Clandinin, T., and Sternberg, P. (1995). Different levels of the C. elegans growth factor LIN-3 promote distinct vulval precursor fates. Cell 82, 297-307.
28. Koller, B.H., Marrack, P., Kappler, J.W., and Smithies, O. (1990). Normal development of mice deficient in beta 2M, MHC class I proteins, and CD8+ T cells. Science 248, 1227-1230.
29. Lardelli, M., Dahlstrand, J., and Lendahl, U. (1994). The novel Notch homologue mouse Notch 3 lacks specific epidermal growth factor-repeats and is expressed in proliferating neuroepithelium. Mech. Dev. 46, 123-136.
30. Lardelli, M., and Lendahl, U. (1993). Motch A and motch B - two mouse Notch homologues coexpressed in a wide variety of tissues. Exp. Cell Res. 204, 364-372.
31. Lieber, T., Kidd, S., Alcamo, E., Corbin, V., and Young, M. (1993). Antineurogenic phenotypes induced by truncated Notch proteins indicate a role in signal transduction and may point to a novel function for Notch in nuclei. Genes Dev. 7, 1949-1965.
32. Lindsell, C., Shawber, C., Boulter, J., and Weinmaster, G. (1995). Jagged: a mammalian ligand that activates Notch1. Cell 80, 909-917.
33. Markowitz, J.S., Auchincloss, H., Jr., Grusby, M.J., and Glimcher, L.H. (1993). Class II-positive hematopoietic cells cannot mediate positive selection of CD4+ T lymphocytes in class II-deficient mice. Proc. Natl. Acad. Sci. USA 90, 2779-2783.
34. Pear, W., Aster, J., Scott, M., Hasserjian, R., Soffer, B., Sklar, J., and Baltimore, D. (1996). Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles. J. Exp. Med. 183, 2283-2291.
35. Ravichandran, K., and Burakoff, S. (1994). Evidence for differential intracellular signaling via CD4 and CD8 molecules. J. Exp. Med. 179, 727-732.
36. Rebay, I., Fehon, R., and Artavanis-Tsakonas, S. (1993). Specific truncations of Drosophila Notch define dominant activated and dominant negative forms of the receptor. Cell 74, 319-329.
37. Robbins, J., Blondel, B., Gallahan, D., and Callahan, R. (1992). Mouse mammary tumor gene int-3: a member of the notch gene family transforms mammary epithelial cells. J. Virol. 66, 2594-2599.
38. Robey, E.A., and Fowlkes, B.J. (1994). Selective events in T cell development. Annu. Rev. Immunol. 12, 675-705.
39. Roehl, H., and Kimble, J. (1993). Control of cell fate in C. elegans by a GLP-1 peptide consisting primarily of ankyrin repeats. Nature 364, 632-635.
40. Sentman, C.L., Shutter, J.R., Hockenbery, D., Kanagawa, O., and Korsmeyer, S. (1991). bcl-2 inhibits multiple forms of apoptosis but not negative seletion in thymocytes. Cell 67, 879-888.
41. Simpson, P. (1995). The Notch connecton. Nature 375, 736-737.
42. Stifani, S., Blaumueller, C., Redhead, N., Hill, R., and Artavanis-Tsakonas, S. (1992). Human homologs of a Drosophila Enhancer of split gene product define a novel family of nuclear proteins. Nature Genetics 2, 119-127.
43. Struhl, G., Fitzgerald, K., and Greenwald, I. (1993). Intrinsic activity of the Lin-12 and Notch intracellular domains in vivo. Cell 74, 331-345.
44. Swiatek, P., Lindsell, C., del Amo, F., Weinmaster, G., and Gridley, T. (1994). Notch1 is essential for postimplantation development in mice. Genes Dev. 8, 707-719.
45. Teh, H.S., Garvin, A.M., Forbush, K.A., Carlow, D.A., Davis, C.B., Littman, D.R., and Perlmutter, R.M. (1991). Participation of CD4 coreceptor molecules in T-cell repertoire selection. Nature 349, 241-243.
46. Tough, D., and Sprent, J. (1994). Turnover of naive-and memory-phenotype T cells. J. Exp. Med. 179, 1127-1135.
47. Weinmaster, G., Roberts, V.J., and Lemke, G. (1991). A homologue of Drosophila Notch expressed during mammalian development. Development 113, 199-205.
48. Weinmaster, G., Roberts, V.J., and Lemke, G. (1992). Notch2: A second mammalian Notch gene. Development 116, 931-941.
49. Wilkinson, H., Fitzgerald, K., and Greenwald, I. (1994). Reciprocal changes in expression of the receptor lin-12 and its ligand prior to commitment in a C. elegans cell fate decision. Cell 79, 1187-1198.
50. Zijlstra, M., Bix, M., Simister, N.E., Loring, J.M., Raulet, D.H., and Jaenisch, R. (1990). Beta 2-Microglobulin deficient mice lack CD4-8+ cytotoxic T cells. Nature 344, 742-746.