Adipose tissue deletion of Gpr116 impairs insulin sensitivity through modulation of adipose function

FEBS Letters

Volumn 586, Issue 20, 2012, Pages 3618-3625

  Nie, Tao ^a   Hui, Xiaoyan ^c   Gao, Xuefei ^a   Li, Kuai ^a   Lin, Wanhua ^a   Xiang, Xiaoliang ^a   Ding, Mengxiao ^a   Kuang, Ying ^b   Xu, Aimin ^a,c   Fei, Jian ^b   Wang, Zhugang ^b   Wu, Donghai ^a  

^a GUANGZHOU INSTITUTES OF BIOMEDICINE AND HEALTH   (China)

^b Shanghai Research Center for Model Organisms   (China)

^c UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

3T3 L1 preadipocyte; Adipogenesis; Adiponectin; Adipose tissue specific knockout; G protein coupled receptor 116 (GPR116); Insulin resistance; Lipodystrophy

Indexed keywords

ADIPONECTIN; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR 116; INSULIN; LIPID; RESISTIN; UNCLASSIFIED DRUG;

ADIPOSE TISSUE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOCHEMISTRY; CELL DIFFERENTIATION; CONTROLLED STUDY; DISEASE SEVERITY; FATTY LIVER; G PROTEIN COUPLED RECEPTOR 116 GENE; GENE DELETION; GLUCOSE INTOLERANCE; IN VITRO STUDY; IN VIVO STUDY; INSULIN RESISTANCE; INSULIN SENSITIVITY; KNOCKOUT MOUSE; LIPID DIET; LIPID STORAGE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROADIPOCYTE; PROTEIN BLOOD LEVEL; PROTEIN FUNCTION; RECEPTOR GENE;

3T3-L1 CELLS; ADIPOCYTES; ADIPOKINES; ADIPOSE TISSUE; ANIMALS; CELL DIFFERENTIATION; CELL SIZE; GENE EXPRESSION REGULATION; GENE KNOCKOUT TECHNIQUES; GLUCOSE INTOLERANCE; HYPERLIPIDEMIAS; INSULIN RESISTANCE; LIPID METABOLISM; MALE; MICE; MICE, INBRED C57BL; RECEPTORS, G-PROTEIN-COUPLED;

MUS;

EID: 84867577749     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2012.08.006     Document Type: Article

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