Targeted disruption of Ig-Hepta/Gpr116 causes emphysema-like symptoms that are associated with alveolar macrophage activation

Journal of Biological Chemistry

Volumn 290, Issue 17, 2015, Pages 11032-11040

  Ariestanti, Donna Maretta ^a   Ando, Hikaru ^a   Hirose, Shigehisa ^a   Nakamura, Nobuhiro ^a  

^a TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL ORGANS; MACROPHAGES; OXYGEN; PROTEINS; SURFACE ACTIVE AGENTS;

ALVEOLAR MACROPHAGES; BRONCHOALVEOLAR LAVAGE FLUID; G PROTEIN COUPLED RECEPTORS; INFLAMMATORY MEDIATORS; MATRIX METALLOPROTEINASES; MONOCYTE CHEMOTACTIC PROTEIN-1; PATHOGENIC MECHANISMS; REACTIVE OXYGEN SPECIES;

MAMMALS;

AUTACOID; CCL1 CHEMOKINE; COLONY STIMULATING FACTOR 1; COMPLEMENT COMPONENT C5; COMPLEMENT COMPONENT C5A; CXCL1 CHEMOKINE; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR 116; GELATINASE A; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 13; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 7; LIPID HYDROPEROXIDE; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MONOCYTE CHEMOTACTIC PROTEIN 1; MONOCYTE CHEMOTACTIC PROTEIN 5; REACTIVE OXYGEN METABOLITE; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; CCL2 PROTEIN, MOUSE; COLLAGENASE; GPR116 PROTEIN, MOUSE;

AGE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL NUCLEUS; CONTROLLED STUDY; DISEASE ASSOCIATION; EMBRYO; ENZYME RELEASE; IMMUNOREGULATION; LUNG ALVEOLUS MACROPHAGE; LUNG EMPHYSEMA; LUNG LAVAGE; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; SYMPTOM; UPREGULATION; ACTIVE TRANSPORT; ANIMAL; DEFICIENCY; GENETICS; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY;

MUS;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; BRONCHOALVEOLAR LAVAGE; CELL NUCLEUS; CHEMOKINE CCL2; COLLAGENASES; INFLAMMATION MEDIATORS; MACROPHAGE ACTIVATION; MACROPHAGES, ALVEOLAR; MICE; MICE, KNOCKOUT; NF-KAPPA B; PULMONARY EMPHYSEMA; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION;

EID: 84928408901     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.648311     Document Type: Article

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