Diverse somatic mutation patterns and pathway alterations in human cancers

Nature

Volumn 466, Issue 7308, 2010, Pages 869-873

  Kan, Zhengyan ^a   Jaiswal, Bijay S ^a   Stinson, Jeremy ^a   Janakiraman, Vasantharajan ^a   Bhatt, Deepali ^a   Stern, Howard M ^a   Yue, Peng ^a   Haverty, Peter M ^a   Bourgon, Richard ^a   Zheng, Jianbiao ^b   Moorhead, Martin ^b   Chaudhuri, Subhra ^a   Tomsho, Lynn P ^c   Peters, Brock A ^a   Pujara, Kanan ^a   Cordes, Shaun ^a   Davis, David P ^a   Carlton, Victoria E H ^b   Yuan, Wenlin ^a   Li, Li ^a   Wang, Weiru ^a   Eigenbrot, Charles ^a   Kaminker, Joshua S ^a   Eberhard, David A ^a   Waring, Paul ^a   Schuster, Stephan C ^c   Modrusan, Zora ^a   Zhang, Zemin ^a   Stokoe, David ^a   De Sauvage, Frederic J ^a   Faham, Malek ^b   Seshagiri, Somasekar ^a   more..

^a GENENTECH INC   (United States)

^b Thermo Fisher Scientific   (United States)

^c PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

G PROTEIN COUPLED RECEPTOR; PROTEIN KINASE; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; MAP2K4 PROTEIN, HUMAN; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4;

CANCER; COHORT ANALYSIS; ENZYME ACTIVITY; GENETIC ANALYSIS; GENOME; MUTATION;

ARTICLE; BREAST CANCER; CONTROLLED STUDY; COPY NUMBER VARIATION; GENE; GENE IDENTIFICATION; HUMAN; HUMAN TISSUE; MUTATION RATE; NEOPLASM; OVARY CANCER; PANCREAS CANCER; PRIORITY JOURNAL; PROSTATE CANCER; SOMATIC MUTATION; TUMOR GENE; TUMOR SUPPRESSOR GENE; BREAST TUMOR; CLASSIFICATION; ENZYMOLOGY; FEMALE; GENETICS; LUNG TUMOR; MALE; METABOLISM; MUTATION; NUCLEOTIDE SEQUENCE; OVARY TUMOR; PATHOLOGY; PROSTATE TUMOR; SIGNAL TRANSDUCTION;

BREAST NEOPLASMS; DNA COPY NUMBER VARIATIONS; DNA MUTATIONAL ANALYSIS; FEMALE; GENES, NEOPLASM; GTP-BINDING PROTEIN ALPHA SUBUNITS; HUMANS; LUNG NEOPLASMS; MALE; MAP KINASE KINASE 4; MUTATION; NEOPLASMS; OVARIAN NEOPLASMS; PROSTATIC NEOPLASMS; PROTEIN KINASES; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION;

EID: 77955660663     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature09208     Document Type: Article

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