메뉴 건너뛰기




Volumn 18, Issue 4, 1998, Pages 514-518

Sol Sherry Lecture in thrombosis: How thrombin 'talks' to cells molecular mechanisms and roles in vivo

Author keywords

Embryonic development; Knockout; Platelets; Protease activated receptors; Thrombin

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; THROMBIN;

EID: 0031956683     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.18.4.514     Document Type: Article
Times cited : (64)

References (26)
  • 1
    • 0014191175 scopus 로고
    • Actions of thrombin and other coagulant and proteolytic enzymes on blood platelets
    • Davey M, Luscher E. Actions of thrombin and other coagulant and proteolytic enzymes on blood platelets. Nature. 1967;216:857-858.
    • (1967) Nature , vol.216 , pp. 857-858
    • Davey, M.1    Luscher, E.2
  • 2
    • 0024391784 scopus 로고
    • Stimulated secretion of endothelial vWF is accompanied by rapid redistribution to the cell surface of the intracellular granule membrane protein GMP-140
    • Hattori R, Hamilton KK, Fugate RD, McEver RP, Sims PJ. Stimulated secretion of endothelial vWF is accompanied by rapid redistribution to the cell surface of the intracellular granule membrane protein GMP-140. J Biol Chem. 1989;264:7768-7771.
    • (1989) J Biol Chem , vol.264 , pp. 7768-7771
    • Hattori, R.1    Hamilton, K.K.2    Fugate, R.D.3    McEver, R.P.4    Sims, P.J.5
  • 3
    • 0023001143 scopus 로고
    • Thrombin stimulates c-sis gene expression in microvascular endothelial cells
    • Daniel TO, Gibbs VC, Milfay DF, Garavoy M, Williams LT. Thrombin stimulates c-sis gene expression in microvascular endothelial cells. J Biol Chem. 1986;261:9579-9582.
    • (1986) J Biol Chem , vol.261 , pp. 9579-9582
    • Daniel, T.O.1    Gibbs, V.C.2    Milfay, D.F.3    Garavoy, M.4    Williams, L.T.5
  • 4
    • 0028222277 scopus 로고
    • Expression of monocyte chemotactic protein-1 by monocytes and endothelial cells exposed to thrombin
    • Colotta F, Sciacca FL, Sironi M, Luini W, Rabiet MJ, Mantovani A. Expression of monocyte chemotactic protein-1 by monocytes and endothelial cells exposed to thrombin. Am J Pathol. 1994;144:975-985.
    • (1994) Am J Pathol , vol.144 , pp. 975-985
    • Colotta, F.1    Sciacca, F.L.2    Sironi, M.3    Luini, W.4    Rabiet, M.J.5    Mantovani, A.6
  • 5
    • 0027492461 scopus 로고
    • Thrombin stimulation of smooth muscle cell proliferation is mediated by a proteolytic, receptor-mediated mechanism
    • McNamara CA, Sarembok IJ, Gimple LW, Fenton JW II, Coughlin SR, Owens GK. Thrombin stimulation of smooth muscle cell proliferation is mediated by a proteolytic, receptor-mediated mechanism. J Clin Invest. 1992;91:94-98.
    • (1992) J Clin Invest , vol.91 , pp. 94-98
    • McNamara, C.A.1    Sarembok, I.J.2    Gimple, L.W.3    Fenton II, J.W.4    Coughlin, S.R.5    Owens, G.K.6
  • 6
    • 0026035523 scopus 로고
    • Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation
    • Vu T-KH, Hung DT, Wheaton VI, Coughlin SR. Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation. Cell. 1991;64:1057-1068.
    • (1991) Cell , vol.64 , pp. 1057-1068
    • Vu, T.-K.H.1    Hung, D.T.2    Wheaton, V.I.3    Coughlin, S.R.4
  • 9
    • 0026782001 scopus 로고
    • The cloned platelet thrombin receptor couples to at least two distinct effectors to stimulate both phosphoinositide hydrolysis and inhibit adenylyl cyclase
    • Hung DT, Wong YH, Vu T-KH, Coughlin SR. The cloned platelet thrombin receptor couples to at least two distinct effectors to stimulate both phosphoinositide hydrolysis and inhibit adenylyl cyclase. J Biol Chem. 1992;353:20831-20834.
    • (1992) J Biol Chem , vol.353 , pp. 20831-20834
    • Hung, D.T.1    Wong, Y.H.2    Vu, T.-K.H.3    Coughlin, S.R.4
  • 10
    • 0029026320 scopus 로고
    • Determinants of thrombin receptor cleavage: Receptor domains involved, specificity, and role of the P3 aspartate
    • Ishii K, Gerszten R, Zheng Y-W, Turck CW, Coughlin SR. Determinants of thrombin receptor cleavage: receptor domains involved, specificity, and role of the P3 aspartate. J Biol Chem. 1995;270:16435-16440.
    • (1995) J Biol Chem , vol.270 , pp. 16435-16440
    • Ishii, K.1    Gerszten, R.2    Zheng, Y.-W.3    Turck, C.W.4    Coughlin, S.R.5
  • 11
    • 0027309290 scopus 로고
    • Kinetics of thrombin receptor cleavage on intact cells: Relation to signaling
    • Ishii K, Hein L, Kobilka B, Coughlin SR. Kinetics of thrombin receptor cleavage on intact cells: relation to signaling. J Biol Chem. 1993;268:9780-9786.
    • (1993) J Biol Chem , vol.268 , pp. 9780-9786
    • Ishii, K.1    Hein, L.2    Kobilka, B.3    Coughlin, S.R.4
  • 13
    • 0026003287 scopus 로고
    • The region of the thrombin receptor resembling hirudin binds to thrombin and alters enzyme specificity
    • Liu L, Vu T-KH, Esmon CT, Coughlin SR. The region of the thrombin receptor resembling hirudin binds to thrombin and alters enzyme specificity. J Biol Chem. 1991;266:16977-16980.
    • (1991) J Biol Chem , vol.266 , pp. 16977-16980
    • Liu, L.1    Vu, T.-K.H.2    Esmon, C.T.3    Coughlin, S.R.4
  • 16
    • 0026775223 scopus 로고
    • Structure-function relationships in the activation of platelet thrombin receptors by receptor-derived peptides
    • Vassallo RRJ, Kieber-Emmons T, Cichowski K, Brass LF. Structure-function relationships in the activation of platelet thrombin receptors by receptor-derived peptides. J Biol Chem. 1992;267:6081-6085.
    • (1992) J Biol Chem , vol.267 , pp. 6081-6085
    • Vassallo, R.R.J.1    Kieber-Emmons, T.2    Cichowski, K.3    Brass, L.F.4
  • 17
    • 0026629249 scopus 로고
    • Tethered ligand agonist peptides: Structural requirements for thrombin receptor activation reveal mechanism of proteolytic unmasking of agonist function
    • Scarborough RM, Naughton M, Teng W, Hung DT, Rose J, Vu T-KH, Wheaton VI, Turck CW, Coughlin SR. Tethered ligand agonist peptides: structural requirements for thrombin receptor activation reveal mechanism of proteolytic unmasking of agonist function. J Biol Chem. 1992;267:13146-13149.
    • (1992) J Biol Chem , vol.267 , pp. 13146-13149
    • Scarborough, R.M.1    Naughton, M.2    Teng, W.3    Hung, D.T.4    Rose, J.5    Vu, T.-K.H.6    Wheaton, V.I.7    Turck, C.W.8    Coughlin, S.R.9
  • 18
    • 0028364862 scopus 로고
    • Thrombin receptor activation: Confirmation of the intramolecular tethered liganding hypothesis and discovery of an alternative intermolecular liganding mode
    • Chen J, Ishii M, Wang L, Ishii K, Coughlin SR. Thrombin receptor activation: confirmation of the intramolecular tethered liganding hypothesis and discovery of an alternative intermolecular liganding mode. J Biol Chem. 1994;269:16041-16045.
    • (1994) J Biol Chem , vol.269 , pp. 16041-16045
    • Chen, J.1    Ishii, M.2    Wang, L.3    Ishii, K.4    Coughlin, S.R.5
  • 19
    • 0026459474 scopus 로고
    • Thrombin receptor activating peptides: Importance of the N-terminal serine and its ionization state as judged by pH dependence, NMR spectroscopy, and cleavage by aminopeptidase M
    • Coller BS, Ward P, Ceruso M, Scudder LE, Springer K, Kutok J, Prestwich GD. Thrombin receptor activating peptides: importance of the N-terminal serine and its ionization state as judged by pH dependence, NMR spectroscopy, and cleavage by aminopeptidase M. Biochemistry. 1992;31:11713-11720.
    • (1992) Biochemistry , vol.31 , pp. 11713-11720
    • Coller, B.S.1    Ward, P.2    Ceruso, M.3    Scudder, L.E.4    Springer, K.5    Kutok, J.6    Prestwich, G.D.7
  • 22
    • 0030066317 scopus 로고    scopus 로고
    • Activating mutations in the thrombin receptor's agonist recognition domain: Mutations in a G protein-coupled receptor's extracellular domain cause transmembrane signaling
    • Nanevicz T, Wang L, Chen M, Ishii M, Coughlin SR. Activating mutations in the thrombin receptor's agonist recognition domain: mutations in a G protein-coupled receptor's extracellular domain cause transmembrane signaling. J Biol Chem. 1996;271:702-706.
    • (1996) J Biol Chem , vol.271 , pp. 702-706
    • Nanevicz, T.1    Wang, L.2    Chen, M.3    Ishii, M.4    Coughlin, S.R.5
  • 23
    • 0029719789 scopus 로고    scopus 로고
    • Desensitization of G protein-coupled receptors
    • discussion 352-353
    • Freedman NJ, Lefkowitz RJ. Desensitization of G protein-coupled receptors. Recent Prog Horm Res. 1996;51:319-351; discussion 352-353.
    • (1996) Recent Prog Horm Res , vol.51 , pp. 319-351
    • Freedman, N.J.1    Lefkowitz, R.J.2
  • 24
    • 0028009801 scopus 로고
    • Inhibition of thrombin receptor signaling by a G protein-coupled receptor kinase: Functional specificity among G protein-coupled receptor kinases
    • Ishii K, Chen J, Ishii M, Koch WJ, Freedman NJ, Lefkowitz RJ, Coughlin SR. Inhibition of thrombin receptor signaling by a G protein-coupled receptor kinase: functional specificity among G protein-coupled receptor kinases. J Biol Chem. 1994;269:1125-1130.
    • (1994) J Biol Chem , vol.269 , pp. 1125-1130
    • Ishii, K.1    Chen, J.2    Ishii, M.3    Koch, W.J.4    Freedman, N.J.5    Lefkowitz, R.J.6    Coughlin, S.R.7
  • 26
    • 0027309290 scopus 로고
    • Kinetics of thrombin receptor cleavage on intact cells: Relation to signaling
    • Ishii K, Hein L, Kobilka B, Coughlin SR. Kinetics of thrombin receptor cleavage on intact cells: relation to signaling. J Biol Chem. 1993;268:9780-9786.
    • (1993) J Biol Chem , vol.268 , pp. 9780-9786
    • Ishii, K.1    Hein, L.2    Kobilka, B.3    Coughlin, S.R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.