Cleavage of polycystin-1 requires the receptor for egg jelly domain and is disrupted by human autosomal-dominant polycystic kidney disease 1-associated mutations

Proceedings of the National Academy of Sciences of the United States of America

Volumn 99, Issue 26, 2002, Pages 16981-16986

  Qian, Feng ^a   Boletta, Alessandra ^a   Bhunia, Anil K ^a   Xu, Hangxue ^a   Liu, Lijuan ^a   Ahrabi, Ali K ^a   Watnick, Terry J ^a   Zhou, Fang ^a   Germino, Gregory G ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

G PROTEIN COUPLED RECEPTOR; POLYCYSTIN; STAT PROTEIN;

ANIMAL CELL; ARTICLE; CELL SURFACE; CONTROLLED STUDY; GENE DISRUPTION; GENE MUTATION; HUMAN; HUMAN CELL; KIDNEY DEVELOPMENT; KIDNEY POLYCYSTIC DISEASE; KIDNEY TUBULE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN SECRETION;

AMINO ACID SEQUENCE; HUMANS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION; POLYCYSTIC KIDNEY, AUTOSOMAL DOMINANT; PROTEINS; RECEPTORS, CELL SURFACE; SIGNAL TRANSDUCTION; TRPP CATION CHANNELS;

ANIMALIA;

EID: 0037168674     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.252484899     Document Type: Article

References (27)

1. Gabow, P. A. (1993) N. Engl. J. Med. 329, 332-342.
2. Peters, D. J. & Sandkuijl, L. A. (1992) Contrib. Nephrol. 97, 128-139.
3. Boulter, C., Mulroy, S., Webb, S., Fleming, S., Brindle, K. & Sandford, R. (2001) Proc. Natl. Acad. Sci. USA 98, 12174-12179.
4. Kim, K., Drummond, I., Ibraghimov-Beskrovnaya, O., Klinger, K. & Arnaout, M. A. (2000) Proc. Natl. Acad. Sci. USA 97, 1731-1736.
5. Boletta, A., Qian, F., Onuchic, L. F., Bhunia, A. K., Phakdeekitcharoen, B., Hanaoka, K., Guggino, W., Monaco, L. & Germino, G. G. (2000) Mol. Cell 6, 1267-1273.
6. Bhunia, A. K., Piontek, K., Boletta, A., Liu, L., Qian, F., Xu, P. N., Germino, F. J. & Germino, G. G. (2002) Cell 109, 157-168.
7. Hughes, J., Ward, C. J., Peral, B., Aspinwall, R., Clark, K., San Millan, J. L., Gamble, V. & Harris, P. C. (1995) Nat. Genet. 10, 151-160.
8. Ibraghimov-Beskrovnaya, O., Bukanov, N. O., Donohue, L. C., Dackowski, W. R., Klinger, K. W. & Landes, G. M. (2000) Hum. Mol. Genet. 9, 1641-1649.
9. Qian, F., Germino, F. J., Cai, Y., Zhang, X., Somlo, S. & Germino, G. G. (1997) Nat. Genet. 16, 179-183.
10. Hanaoka, K., Qian, F., Boletta, A., Bhunia, A. K., Piontek, K., Tsiokas, L., Sukhatme, V. P., Guggino, W. B. & Germino, G. G. (2000) Nature 408, 990-994.
11. Parnell, S. C., Magenheimer, B. S., Maser, R. L., Rankin, C. A., Smine, A., Okamoto, T. & Calvet, J. P. (1998) Biochem. Biophys. Res. Commun. 251, 625-631.
12. Delmas, P., Nomura, H., Li, X., Lakkis, M., Luo, Y., Segal, Y., Fernandez-Fernandez, J. M., Harris, P., Frischauf, A. M., Brown, D. A., et al. (2002) J. Biol. Chem. 277, 11276-11283.
13. Moy, G. W., Mendoza, L. M., Schulz, J. R., Swanson, W. J., Glabe, C. G. & Vacquier, V. D. (1996) J. Cell Biol. 133, 809-817.
14. Ponting, C. P., Hofmann, K. & Bork, P. (1999) Curr. Biol. 9, R585-R588.
15. Krasnoperov, V. G., Bittner, M. A., Beavis, R., Kuang, Y., Salnikow, K. V., Chepurny, O. G., Little, A. R., Plotnikov, A. N., Wu, D., Holz, R. W., et al. (1997) Neuron 18, 925-937.
16. Stacey, M., Lin, H. H., Gordon, S. & McKnight, A. J. (2000) Trends Biochem. Sci. 25, 284-289.
17. Mengerink, K. J., Moy, G. W. & Vacquier, V. D. (2002) J. Biol. Chem. 277, 943-948.
18. Boletta, A., Qian, F., Onuchic, L. F., Bragonzi, A., Cortese, M., Deen, P. M., Courtoy, P. J., Soria, M. R., Devuyst, O., Monaco, L., et al. (2001) Am. J. Kidney Dis. 38, 1421-1429.
19. Rossetti, S., Strmecki, L., Gamble, V., Burton, S., Sneddon, V., Peral, B., Roy, S., Bakkaloglu, A., Komel, R., Winearls, C. G., et al. (2001) Am. J. Hum. Genet. 68, 46-63.
20. Watnick, T. J., Torres, V. E., Gandolph, M. A., Qian, F., Onuchic, L. F., Klinger, K. W., Landes, G. & Germino, G. G. (1998) Mol. Cell 2, 247-251.
21. Koptides, M., Mean, R., Demetriou, K., Constantinides, R., Pierides, A., Harris, P. C. & Deltas, C. C. (2001) Hum. Mutat. 16, 176.
22. Watnick, T. J., Piontek, K. B., Cordal, T. M., Weber, H., Gandolph, M. A., Qian, F., Lens, X. M., Neumann, H. P. & Germino, G. G. (1997) Hum. Mol. Genet. 6, 1473-1481.
23. Williams, J. F., McClain, D. A., Dull, T. J., Ullrich, A. & Olefsky, J. M. (1990) J. Biol. Chem. 265, 8463-8469.
24. Krasnoperov, V., Bittner, M. A., Holz, R. W., Chepurny, O. & Petrenko A. G. (1999) J. Biol. Chem. 274, 3590-3596.
25. Yoshimasa, Y., Seino, S., Whittaker, J., Kakehi, T., Kosaki, A., Kuzuya, H., Imura, H., Bell, G. I. & Steiner, D. F. (1988) Science 240, 784-787.
26. Thinakaran, G., Borchelt, D. R., Lee, M. K., Slunt, H. H., Spitzer, L., Kim, G., Ratovitsky, T., Davenport, F., Nordstedt, C., Seeger, M., et al. (1996) Neuron 17, 181-190.
27. Gray, J. X., Haino, M., Roth, M. J., Maguire, J. E., Jensen, P. N., Yarme, A., Stetler-Stevenson, M. A., Siebenlist, U. & Kelly, K. (1996) J. Immunol. 157, 5438-5447.