Orphan G protein-coupled receptor GPR56 regulates neural progenitor cell migration via a Gα12/13 and Rho pathway

Journal of Biological Chemistry

Volumn 283, Issue 21, 2008, Pages 14469-14478

  Iguchi, Tokuichi ^a   Sakata, Kensei ^a   Yoshizaki, Kotaro ^a   Tago, Kenji ^a   Mizuno, Norikazu ^a   Itoh, Hiroshi ^a  

^a NARA INSTITUTE OF SCIENCE AND TECHNOLOGY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CELL ADHESION; CELL MEMBRANES; CLARIFICATION; CYTOLOGY; NUCLEIC ACIDS; PIGMENTS; TRANSCRIPTION;

ACTIN FIBERS; ACTIN REORGANIZATIONS; AGONISTIC ACTIVITIES; BRAIN DEVELOPMENTS; CELL SURFACES; CENTRAL NERVOUS SYSTEMS; COUPLED RECEPTORS; DO-MAINS; DOMINANT NEGATIVES; EXPRESSION LEVELS; G PROTEINS; GUANINE NUCLEOTIDE EXCHANGE FACTORS; NEURAL PROGENITOR CELLS; SIGNALING PATHWAYS; TRANSCRIPTIONAL ACTIVATIONS;

ADHESION;

EXOENZYME C3; F ACTIN; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR 56; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; GUANINE NUCLEOTIDE EXCHANGE FACTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; P115 RHO SPECIFIC GUANINE NUCLEOTIDE EXCHANGE FACTOR; PROTEIN ANTIBODY; RGS PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG; ACTIN; ANTIBODY; GPR56 PROTEIN, MOUSE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN;

ANIMAL CELL; ARTICLE; CELL MIGRATION; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; HUMAN; HUMAN CELL; MOUSE; NERVOUS SYSTEM DEVELOPMENT; NEURAL STEM CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; REGULATORY MECHANISM; SERUM RESPONSIVE ELEMENT; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; ANIMAL; CELL LINE; CELL MEMBRANE; CELL MOTION; CYTOLOGY; DRUG EFFECT; DRUG POTENTIATION; ENZYME ACTIVATION; GENETICS; IMMUNOLOGY; METABOLISM; NERVE CELL; STEM CELL;

ACTINS; ANIMALS; ANTIBODIES; CELL LINE; CELL MEMBRANE; CELL MOVEMENT; ENZYME ACTIVATION; GTP-BINDING PROTEIN ALPHA SUBUNITS, G12-G13; HUMANS; MICE; NEURONS; NF-KAPPA B; RECEPTORS, G-PROTEIN-COUPLED; RHOA GTP-BINDING PROTEIN; SERUM RESPONSE ELEMENT; SIGNAL TRANSDUCTION; STEM CELLS;

EID: 47249103800     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M708919200     Document Type: Article

References (50)

1. Marin, O., and Rubenstein, J. L. (2003) Annu. Rev. Neurosci. 26, 441-483
2. Bielas, S., Higginbotham, H., Koizumi, H., Tanaka, T., and Gleeson, J. G. (2004) Annu. Rev. Cell Dev. Biol. 20, 593-618
3. Marin, O., Valdeolmillos, M., and Moya, F. (2006) Trends Neurosci. 29, 655-661
4. D'Arcangelo, G., Miao, G. G., Chen, S. C., Soares, H. D., Morgan, J. I., and Curran, T. (1995) Nature 374, 719-723
5. Hirotsune, S., Takahara, T., Sasaki, N., Hirose, K., Yoshiki, A., Ohashi, T., Kusakabe, M., Murakami, Y., Muramatsu, M., and Watanabe, S. (1995) Nat. Genet. 10, 77-83
6. Ogawa, M., Miyata, T., Nakajima, K., Yagyu, K., Seike, M., Ikenaka, K., Yamamoto, H., and Mikoshiba, K. (1995) Neuron 14, 899-912
7. Reiner, O., Carrozzo, R., Shen, Y., Wehnert, M., Faustinella, F., Dobyns, W. B., Caskey, C. T., and Ledbetter, D. H. (1993) Nature 364, 717-721
8. Hattori, M., Adachi, H., Tsujimoto, M., Arai, H., and Inoue, K. (1994) Nature 370, 216-218
9. des Portes, V., Pinard, J. M., Billuart, P., Vinet, M. C., Koulakoff, A., Carrie, A., Gelot, A., Dupuis, E., Motte, J., Berwald-Netter, Y., Catala, M., Kahn, A., Beldjord, C., and Chelly, J. (1998) Cell 92, 51-61
10. Gleeson, J. G., Allen, K. M., Fox, J. W., Lamperti, E. D., Berkovic, S., Scheffer, I., Cooper, E. C., Dobyns, W. B., Minnerath, S. R., Ross, M. E., and Walsh, C. A. (1998) Cell 92, 63-72
11. Etienne-Manneville, S., and Hall, A. (2002) Nature 420, 629-635
12. Kholmanskikh, S. S., Dobrin, J. S., Wynshaw-Boris, A., Letourneau, P. C., and Ross, M. E. (2003) J. Neurosci. 23, 8673-8681
13. Gilman, A. G. (1987) Annu. Rev. Biochem. 56, 615-649
14. Marinissen, M. J., and Gutkind, J. S. (2001) Trends Pharmacol. Sci. 22, 368-376
15. Kaziro, Y., Itoh, H., Kozasa, T., Nakafuku, M., and Satoh, T. (1991) Annu. Rev. Biochem. 60, 349-400
16. Milligan, G., and Kostenis, E. (2006) Br. J. Pharmacol. 147, Suppl. 1, S46-S55
17. Behar, T. N., Schaffner, A. E., Scott, C. A., Greene, C. L., and Barker, J. L. (2000) Cereb. Cortex 10, 899-909
18. Behar, T. N., Smith, S. V., Kennedy, R. T., McKenzie, J. M., Maric, I., and Barker, J. L. (2001) Cereb. Cortex 11, 744-753
19. Stumm, R. K., Zhou, C., Ara, T., Lazarini, F., Dubois-Dalcq, M., Nagasawa, T., Hollt, V., and Schulz, S. (2003) J. Neurosci. 23, 5123-5130
20. Mizuno, N., Kokubu, H., Sato, M., Nishimura, A., Yamauchi, J., Kurose, H., and Itoh, H. (2005) Proc. Natl. Acad. Sci. U. S. A. 102, 12365-12370
21. Shinohara, H., Udagawa, J., Morishita, R., Ueda, H., Otani, H., Semba, R., Kato, K., and Asano, T. (2004) J. Biol. Chem. 279, 41141-41148
22. Liu, M., Parker, R. M., Darby, K., Eyre, H. J., Copeland, N. G., Crawford, J., Gilbert, D. J., Sutherland, G. R., Jenkins, N. A., and Herzog, H. (1999) Genomics 55, 296-305
23. Fredriksson, R., Lagerstrom, M. C., Hoglund, P. J., and Schioth, H. B. (2002) FEBS Lett. 531, 407-414
24. Fredriksson, R., Gloriam, D. E., Hoglund, P. J., Lagerstrom, M. C., and Schioth, H. B. (2003) Biochem. Biophys. Res. Commun. 301, 725-734
25. Bjarnadottir, T. K., Fredriksson, R., Hoglund, P. J., Gloriam, D. E., Lagerstrom, M. C., and Schioth, H. B. (2004) Genomics 84, 23-33
26. Bjarnadottir, T. K., Fredriksson, R., and Schioth, H. B. (2007) Cell Mol. Life Sci. 64, 2104-2119
27. Piao, X., Hill, R. S., Bodell, A., Chang, B. S., Basel-Vanagaite, L., Straussberg, R., Dobyns, W. B., Qasrawi, B., Winter, R. M., Innes, A. M., Voit, T., Ross, M. E., Michaud, J. L., Descarie, J. C., Barkovich, A. J., and Walsh, C. A. (2004) Science 303, 2033-2036
28. Jin, Z., Tietjen, I., Bu, L., Liu-Yesucevitz, L., Gaur, S. K., Walsh, C. A., and Piao, X. (2007) Hum. Mol. Genet. 16, 1972-1985
29. Terskikh, A. V., Easterday, M. C., Li, L., Hood, L., Kornblum, H. I., Geschwind, D. H., and Weissman, I. L. (2001) Proc. Natl. Acad. Sci. U. S. A. 98, 7934-7939
30. Zendman, A. J., Cornelissen, I. M., Weidle, U. H., Ruiter, D. J., and van Muijen, G. N. (1999) FEBS Lett. 446, 292-298
31. Shashidhar, S., Lorente, G., Nagavarapu, U., Nelson, A., Kuo, J., Cummins, J., Nikolich, K., Urfer, R., and Foehr, E. D. (2005) Oncogene 24, 1673-1682
32. Xu, L., Begum, S., Hearn, J. D., and Hynes, R. O. (2006) Proc. Natl. Acad. Sci. U. S. A. 103, 9023-9028
33. Sud, N., Sharma, R., Ray, R., Chattopadhyay, T. K., and Ralhan, R. (2006) Cancer Lett. 233, 265-270
34. Ke, N., Sundaram, R., Liu, G., Chionis, J., Fan, W., Rogers, C., Awad, T., Grifman, M., Yu, D., Wong-Staal, F., and Li, Q. X. (2007) Mol. Cancer Ther. 6, 1840-1850
35. Arai, K., Maruyama, Y., Nishida, M., Tanabe, S., Takagahara, S., Kozasa, T., Mori, Y., Nagao, T., and Kurose, H. (2003) Mol. Pharmacol. 63, 478-488
36. Sun, Y., Yamauchi, J., Kaziro, Y., and Itoh, H. (1999) J. Biochem. (Tokyo) 125, 515-521
37. Yamauchi, J., Hirasawa, A., Miyamoto, Y., Itoh, H., and Tsujimoto, G. (2001) Biochem. Biophys. Res. Commun. 284, 1199-1203
38. Takasaki, J., Saito, T., Taniguchi, M., Kawasaki, T., Moritani, Y., Hayashi, K., and Kobori, M. (2004) J. Biol. Chem. 279, 47438-47445
39. Seifert, R., and Wenzel-Seifert, K. (2002) Naunyn-Schmiedebergs Arch. Pharmacol. 366, 381-416
40. Kabarowski, J. H., Feramisco, J. D., Le, L. Q., Gu, J. L., Luoh, S. W., Simon, M. I., and Witte, O. N. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 12109-12114
41. Elies, R., Fu, L. X., Eftekhari, P., Wallukat, G., Schulze, W., Granier, C., Hjalmarson, A., and Hoebeke, J. (1998) Eur. J. Biochem. 251, 659-666
42. Schott, M., Scherbaum, W. A., and Morgenthaler, N. G. (2005) Trends Endocrinol. Metab. 16, 243-248
43. Makita, N., Sato, J., Manaka, K., Shoji, Y., Oishi, A., Hashimoto, M., Fujita, T., and Iiri, T. (2007) Proc. Natl. Acad. Sci. U. S. A. 104, 5443-5448
44. Tabata, H., and Nakajima, K. (2003) J. Neurosci. 23, 9996-10001
45. Nadarajah, B., Alifragis, P., Wong, R. O., and Parnavelas, J. G. (2003) Cereb. Cortex 13, 607-611
46. Fesus, L., and Piacentini, M. (2002) Trends Biochem. Sci. 27, 534-539
47. Fukushima, N., Weiner, J. A., and Chun, J. (2000) Dev. Biol. 228, 6-18
48. Moers, A., Nurnberg, A., Goebbels, S., Wettschureck, N., and Offermanns, S. (2008) Mol. Cell. Biol. 28, 1480-1488
49. Little, K. D., Hemler, M. E., and Stipp, C. S. (2004) Mol. Biol. Cell 15, 2375-2387
50. Geisert, E. E., Jr., Williams, R. W., Geisert, G. R., Fan, L., Asbury, A. M., Maecker, H. T., Deng, J., and Levy, S. (2002) J. Comp. Neurol. 453, 22-32