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Volumn 287, Issue 12, 2012, Pages 9399-9413

High affinity neurexin binding to cell adhesion G-protein-coupled receptor CIRL1/latrophilin-1 produces an intercellular adhesion complex

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEINS; ALTERNATIVE SPLICING; ANKYRIN; BINDING ASSAYS; BINDING INTERACTION; BLACK WIDOW SPIDERS; CELL-ADHESION ASSAYS; DELETION MAPPING; EXTRACELLULAR; EXTRACELLULAR DOMAINS; G PROTEIN COUPLED RECEPTORS; HIGH AFFINITY; INTERCELLULAR ADHESION; MEMBRANE PROTEINS; NANOMOLAR AFFINITY; NEUREXINS; NEURONAL CELL; NEUROTRANSMITTER RELEASE; NOVEL LIGANDS; PRESYNAPTIC; SPLICE SITE;

EID: 84858597379     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.318659     Document Type: Article
Times cited : (142)

References (53)
  • 1
    • 0034917524 scopus 로고    scopus 로고
    • α-Latrotoxin and its receptors: Neurexins and CIRL/ latrophilins
    • Südhof, T. C. (2001) α-Latrotoxin and its receptors: neurexins and CIRL/ latrophilins. Annu. Rev. Neurosci. 24, 933-962
    • (2001) Annu. Rev. Neurosci. , vol.24 , pp. 933-962
    • Südhof, T.C.1
  • 2
    • 0026769035 scopus 로고
    • Neurexins: Synaptic cell surface proteins related to the α-latrotoxin receptor and laminin
    • Ushkaryov, Y. A., Petrenko, A. G., Geppert, M., and Südhof, T. C. (1992) Neurexins: synaptic cell surface proteins related to the α-latrotoxin receptor and laminin. Science 257, 50-56
    • (1992) Science , vol.257 , pp. 50-56
    • Ushkaryov, Y.A.1    Petrenko, A.G.2    Geppert, M.3    Südhof, T.C.4
  • 3
    • 0033103549 scopus 로고    scopus 로고
    • Neurexins are functional α-latrotoxin receptors
    • Sugita, S., Khvochtev, M., and Südhof, T. C. (1999) Neurexins are functional α-latrotoxin receptors. Neuron 22, 489-496 (Pubitemid 29159848)
    • (1999) Neuron , vol.22 , Issue.3 , pp. 489-496
    • Sugita, S.1    Khvochtev, M.2    Sudhof, T.C.3
  • 6
    • 0032484023 scopus 로고    scopus 로고
    • α-Latrotoxin receptor CIRL/latrophilin 1 (CL1) defines an unusual family of ubiquitous G-protei-linked receptors: G-protein coupling not required for triggering exocytosis
    • DOI 10.1074/jbc.273.49.32715
    • Sugita, S., Ichtchenko, K., Khvotchev, M., and Südhof, T. C. (1998) α-Latrotoxin receptor CIRL/latrophilin 1 (CL1) defines an unusual family of ubiquitous G-protein-linked receptors. G-protein coupling not required for triggering exocytosis. J. Biol. Chem. 273, 32715-32724 (Pubitemid 28557656)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.49 , pp. 32715-32724
    • Sugita, S.1    Ichtchenko, K.2    Khvotchev, M.3    Sudhof, T.C.4
  • 8
    • 0028241554 scopus 로고
    • Conserved domain structure of β-neurexins. Unusual cleaved signal sequences in receptor-like neuronal cell-surface proteins
    • Ushkaryov, Y. A., Hata, Y., Ichtchenko, K., Moomaw, C., Afendis, S., Slaughter, C. A., and Südhof, T. C. (1994) Conserved domain structure of β-neurexins. Unusual cleaved signal sequences in receptor-like neuronal cell-surface proteins. J. Biol. Chem. 269, 11987-11992
    • (1994) J. Biol. Chem. , vol.269 , pp. 11987-11992
    • Ushkaryov, Y.A.1    Hata, Y.2    Ichtchenko, K.3    Moomaw, C.4    Afendis, S.5    Slaughter, C.A.6    Südhof, T.C.7
  • 9
    • 0036270811 scopus 로고    scopus 로고
    • Structure and evolution of neurexin genes: Insight into the mechanism of alternative splicing
    • DOI 10.1006/geno.2002.6780
    • Tabuchi, K., and Südhof, T. C. (2002) Structure and evolution of neurexin genes: insight into the mechanism of alternative splicing. Genomics 79, 849-859 (Pubitemid 34595320)
    • (2002) Genomics , vol.79 , Issue.6 , pp. 849-859
    • Tabuchi, K.1    Sudhof, T.C.2
  • 10
    • 0036210068 scopus 로고    scopus 로고
    • Analysis of the human neurexin genes: Alternative splicing and the generation of protein diversity
    • DOI 10.1006/geno.2002.6734
    • Rowen, L., Young, J., Birditt, B., Kaur, A., Madan, A., Philipps, D. L., Qin, S., Minx, P., Wilson, R. K., Hood, L., and Graveley, B. R. (2002) Analysis of the human neurexin genes: alternative splicing and the generation of protein diversity. Genomics 79, 587-597 (Pubitemid 34274301)
    • (2002) Genomics , vol.79 , Issue.4 , pp. 587-597
    • Rowen, L.1    Young, J.2    Birditt, B.3    Kaur, A.4    Madan, A.5    Philipps, D.L.6    Qin, S.7    Minx, P.8    Wilson, R.K.9    Hood, L.10    Graveley, B.R.11
  • 11
    • 0028969264 scopus 로고
    • Cartography of neurexins: More than 1000 isoforms generated by alternative splicing and expressed in distinct subsets of neurons
    • Ullrich, B., Ushkaryov, Y. A., and Südhof, T. C. (1995) Cartography of neurexins: more than 1000 isoforms generated by alternative splicing and expressed in distinct subsets of neurons. Neuron 14, 497-507
    • (1995) Neuron , vol.14 , pp. 497-507
    • Ullrich, B.1    Ushkaryov, Y.A.2    Südhof, T.C.3
  • 14
    • 0030026657 scopus 로고    scopus 로고
    • Structures, alternative splicing, and neurexin binding of multiple neuroligins
    • DOI 10.1074/jbc.271.5.2676
    • Ichtchenko, K., Nguyen, T., and Südhof, T. C. (1996) Structures, alternative splicing, and neurexin binding of multiple neuroligins. J. Biol. Chem. 271, 2676-2682 (Pubitemid 26047882)
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.5 , pp. 2676-2682
    • Ichtchenko, K.1    Nguyen, T.2    Sudhof, T.C.3
  • 15
    • 26944444692 scopus 로고    scopus 로고
    • A splice code for trans-synaptic cell adhesion mediated by binding of neuroligin 1 to α- and β-neurexins
    • DOI 10.1016/j.neuron.2005.08.026, PII S0896627305007014
    • Boucard, A. A., Chubykin, A. A., Comoletti, D., Taylor, P., and Südhof, T. C. (2005) A splice code for trans-synaptic cell adhesion mediated by binding of neuroligin 1 to α- and β-neurexins. Neuron 48, 229-236 (Pubitemid 41476357)
    • (2005) Neuron , vol.48 , Issue.2 , pp. 229-236
    • Boucard, A.A.1    Chubykin, A.A.2    Comoletti, D.3    Taylor, P.4    Sudhof, T.C.5
  • 16
    • 33745994650 scopus 로고    scopus 로고
    • Alternative Splicing Controls Selective Trans-Synaptic Interactions of the Neuroligin-Neurexin Complex
    • DOI 10.1016/j.neuron.2006.06.005, PII S0896627306004582
    • Chih, B., Gollan, L., and Scheiffele, P. (2006) Alternative splicing controls selective trans-synaptic interactions of the neuroligin-neurexin complex. Neuron 51, 171-178 (Pubitemid 44063616)
    • (2006) Neuron , vol.51 , Issue.2 , pp. 171-178
    • Chih, B.1    Gollan, L.2    Scheiffele, P.3
  • 17
    • 72149130256 scopus 로고    scopus 로고
    • LRRTM2 functions as a neurexin ligand in promoting excitatory synapse formation
    • Ko, J., Fuccillo, M. V., Malenka, R. C., and Südhof, T. C. (2009) LRRTM2 functions as a neurexin ligand in promoting excitatory synapse formation. Neuron 64, 791-798
    • (2009) Neuron , vol.64 , pp. 791-798
    • Ko, J.1    Fuccillo, M.V.2    Malenka, R.C.3    Südhof, T.C.4
  • 19
    • 77953206739 scopus 로고    scopus 로고
    • LRRTMs and neuroligins bind neurexins with a differential code to cooperate in glutamate synapse development
    • Siddiqui, T. J., Pancaroglu, R., Kang, Y., Rooyakkers, A., and Craig, A. M. (2010) LRRTMs and neuroligins bind neurexins with a differential code to cooperate in glutamate synapse development. J. Neurosci. 30, 7495-7506
    • (2010) J. Neurosci. , vol.30 , pp. 7495-7506
    • Siddiqui, T.J.1    Pancaroglu, R.2    Kang, Y.3    Rooyakkers, A.4    Craig, A.M.5
  • 20
    • 77953725365 scopus 로고    scopus 로고
    • Trans-synaptic interaction of GluRδ2 and Neurexin through Cbln1 mediates synapse formation in the cerebellum
    • Uemura, T., Lee, S. J., Yasumura, M., Takeuchi, T., Yoshida, T., Ra, M., Taguchi, R., Sakimura, K., and Mishina, M. (2010) Trans-synaptic interaction of GluRδ2 and Neurexin through Cbln1 mediates synapse formation in the cerebellum. Cell 141, 1068-1079
    • (2010) Cell , vol.141 , pp. 1068-1079
    • Uemura, T.1    Lee, S.J.2    Yasumura, M.3    Takeuchi, T.4    Yoshida, T.5    Ra, M.6    Taguchi, R.7    Sakimura, K.8    Mishina, M.9
  • 21
    • 79954486224 scopus 로고    scopus 로고
    • Cbln family proteins promote synapse formation by regulating distinct neurexin signaling pathways in various brain regions
    • Matsuda, K., and Yuzaki, M. (2011) Cbln family proteins promote synapse formation by regulating distinct neurexin signaling pathways in various brain regions. Eur. J. Neurosci. 33, 1447-1461
    • (2011) Eur. J. Neurosci. , vol.33 , pp. 1447-1461
    • Matsuda, K.1    Yuzaki, M.2
  • 22
    • 0034625250 scopus 로고    scopus 로고
    • Neuroligin expressed in nonneuronal cells triggers presynaptic development in contacting axons
    • Scheiffele, P., Fan, J., Choih, J., Fetter, R., and Serafini, T. (2000) Neuroligin expressed in nonneuronal cells triggers presynaptic development in contacting axons. Cell 101, 657-669
    • (2000) Cell , vol.101 , pp. 657-669
    • Scheiffele, P.1    Fan, J.2    Choih, J.3    Fetter, R.4    Serafini, T.5
  • 23
    • 20644443891 scopus 로고    scopus 로고
    • Dissection of synapse induction by neuroligins: Effect of a neuroligin mutation associated with autism
    • DOI 10.1074/jbc.M410723200
    • Chubykin, A. A., Liu, X., Comoletti, D., Tsigelny, I., Taylor, P., and Südhof, T. C. (2005) Dissection of synapse induction by neuroligins: effect of a neuroligin mutation associated with autism. J. Biol. Chem. 280, 22365-22374 (Pubitemid 40834299)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.23 , pp. 22365-22374
    • Chubykin, A.A.1    Liu, X.2    Comoletti, D.3    Tsigelny, I.4    Taylor, P.5    Sudhof, T.C.6
  • 24
    • 70350336261 scopus 로고    scopus 로고
    • Neuroligin-1 performs neurexin-dependent and neurexin-independent functions in synapse validation
    • Ko, J., Zhang, C., Arac, D., Boucard, A. A., Brunger, A. T., and Südhof, T. C. (2009) Neuroligin-1 performs neurexin-dependent and neurexin-independent functions in synapse validation. EMBO J. 28, 3244-3255
    • (2009) EMBO J. , vol.28 , pp. 3244-3255
    • Ko, J.1    Zhang, C.2    Arac, D.3    Boucard, A.A.4    Brunger, A.T.5    Südhof, T.C.6
  • 25
    • 11144352245 scopus 로고    scopus 로고
    • Neurexins induce differentiation of GABA and glutamate postsynaptic specializations via neuroligins
    • DOI 10.1016/j.cell.2004.11.035, PII S0092867404011031
    • Graf, E. R., Zhang, X., Jin, S. X., Linhoff, M. W., and Craig, A. M. (2004) Neurexins induce differentiation of GABA and glutamate postsynaptic specializations via neuroligins. Cell 119, 1013-1026 (Pubitemid 40037614)
    • (2004) Cell , vol.119 , Issue.7 , pp. 1013-1026
    • Graf, E.R.1    Zhang, X.2    Jin, S.-X.3    Linhoff, M.W.4    Craig, A.M.5
  • 28
  • 32
    • 80054962735 scopus 로고    scopus 로고
    • Compound heterozygous deletion of NRXN1 causing severe developmental delay with early onset epilepsy in two sisters
    • Harrison, V., Connell, L., Hayesmoore, J., McParland, J., Pike, M. G., and Blair, E. (2011) Compound heterozygous deletion of NRXN1 causing severe developmental delay with early onset epilepsy in two sisters. Am. J. Med. Genet. A 155A, 2826-2831
    • (2011) Am. J. Med. Genet. A , vol.155 A , pp. 2826-2831
    • Harrison, V.1    Connell, L.2    Hayesmoore, J.3    McParland, J.4    Pike, M.G.5    Blair, E.6
  • 35
    • 54049091941 scopus 로고    scopus 로고
    • Neuroligins and neurexins link synaptic function to cognitive disease
    • Südhof, T. C. (2008) Neuroligins and neurexins link synaptic function to cognitive disease. Nature 455, 903-911
    • (2008) Nature , vol.455 , pp. 903-911
    • Südhof, T.C.1
  • 38
    • 0034693141 scopus 로고    scopus 로고
    • The calcium-independent receptor for α-latrotoxin from human and rodent brains interacts with members of the ProSAP/SSTRIP/ Shank family of multidomain proteins
    • Kreienkamp, H. J., Zitzer, H., Gundelfinger, E. D., Richter, D., and Bockers, T. M. (2000) The calcium-independent receptor for α-latrotoxin from human and rodent brains interacts with members of the ProSAP/SSTRIP/ Shank family of multidomain proteins. J. Biol. Chem. 275, 32387-32390
    • (2000) J. Biol. Chem. , vol.275 , pp. 32387-32390
    • Kreienkamp, H.J.1    Zitzer, H.2    Gundelfinger, E.D.3    Richter, D.4    Bockers, T.M.5
  • 40
    • 0344382111 scopus 로고    scopus 로고
    • Neurexophilins form a conserved family of neuropeptide-like glycoproteins
    • Missler, M., and Südhof, T. C. (1998) Neurexophilins form a conserved family of neuropeptide-like glycoproteins. J. Neurosci. 18, 3630-3638 (Pubitemid 28225671)
    • (1998) Journal of Neuroscience , vol.18 , Issue.10 , pp. 3630-3638
    • Missler, M.1    Sudhof, T.C.2
  • 41
    • 0035939672 scopus 로고    scopus 로고
    • A stoichiometric complex of neurexins and dystroglycan in brain
    • DOI 10.1083/jcb.200105003
    • Sugita, S., Saito, F., Tang, J., Satz, J., Campbell, K., and Südhof, T. C. (2001) A stoichiometric complex of neurexins and dystroglycan in brain. J. Cell Biol. 154, 435-445 (Pubitemid 34286152)
    • (2001) Journal of Cell Biology , vol.154 , Issue.2 , pp. 435-445
    • Sugita, S.1    Saito, F.2    Tang, J.3    Satz, J.4    Campbell, K.5    Sudhof, T.C.6
  • 44
    • 0037155203 scopus 로고    scopus 로고
    • Genetic analysis of α-latrotoxin receptors reveals functional interdependence of CIRL/latrophilin 1 and neurexin 1α
    • DOI 10.1074/jbc.M111231200
    • Tobaben, S., Südhof, T. C., and Stahl, B. (2002) Genetic analysis of α-latrotoxin receptors reveals functional interdependence of CIRL/latrophilin 1 and neurexin 1α. J. Biol. Chem. 277, 6359-6365 (Pubitemid 34968429)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.8 , pp. 6359-6365
    • Tobaben, S.1    Sudhof, T.C.2    Stahl, B.3
  • 46
    • 33947314576 scopus 로고    scopus 로고
    • Regulation of receptor trafficking by GRKs and arrestins
    • DOI 10.1146/annurev.physiol.69.022405.154712
    • Moore, C. A., Milano, S. K., and Benovic, J. L. (2007) Regulation of receptor trafficking by GRKs and arrestins. Annu. Rev. Physiol. 69, 451-482 (Pubitemid 46457651)
    • (2007) Annual Review of Physiology , vol.69 , pp. 451-482
    • Moore, C.A.C.1    Milano, S.K.2    Benovic, J.L.3
  • 47
    • 1842328567 scopus 로고    scopus 로고
    • Binding properties of neuroligin 1 and neurexin 1β reveal function as heterophilic cell adhesion molecules
    • DOI 10.1074/jbc.272.41.26032
    • Nguyen, T., and Südhof, T. C. (1997) Binding properties of neuroligin 1 and neurexin 1β reveal function as heterophilic cell adhesion molecules. J. Biol. Chem. 272, 26032-26039 (Pubitemid 27438933)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.41 , pp. 26032-26039
    • Nguyen, T.1    Sudhof, T.C.2
  • 48
    • 79954580213 scopus 로고    scopus 로고
    • A review on cognitive and brain endophenotypes that may be common in autism spectrum disorder and attention-deficit/hyperactivity disorder and facilitate the search for pleiotropic genes
    • Rommelse, N. N., Geurts, H. M., Franke, B., Buitelaar, J. K., and Hartman, C. A. (2011) A review on cognitive and brain endophenotypes that may be common in autism spectrum disorder and attention-deficit/hyperactivity disorder and facilitate the search for pleiotropic genes. Neurosci. Biobehav. Rev. 35, 1363-1396
    • (2011) Neurosci. Biobehav. Rev. , vol.35 , pp. 1363-1396
    • Rommelse, N.N.1    Geurts, H.M.2    Franke, B.3    Buitelaar, J.K.4    Hartman, C.A.5
  • 51
    • 69949146214 scopus 로고    scopus 로고
    • Presynaptic targeting of α4β2 nicotinic acetylcholine receptors is regulated by neurexin-1β
    • Cheng, S. B., Amici, S. A., Ren, X. Q., McKay, S. B., Treuil, M. W., Lindstrom, J. M., Rao, J., and Anand, R. (2009) Presynaptic targeting of α4β2 nicotinic acetylcholine receptors is regulated by neurexin-1β. J. Biol. Chem. 284, 23251-23259
    • (2009) J. Biol. Chem. , vol.284 , pp. 23251-23259
    • Cheng, S.B.1    Amici, S.A.2    Ren, X.Q.3    McKay, S.B.4    Treuil, M.W.5    Lindstrom, J.M.6    Rao, J.7    Anand, R.8
  • 52
    • 0034680783 scopus 로고    scopus 로고
    • The G protein-coupled receptor CL1 interacts directly with proteins of the Shank family
    • Tobaben, S., Südhof, T. C., and Stahl, B. (2000) The G protein-coupled receptor CL1 interacts directly with proteins of the Shank family. J. Biol. Chem. 275, 36204-36210
    • (2000) J. Biol. Chem. , vol.275 , pp. 36204-36210
    • Tobaben, S.1    Südhof, T.C.2    Stahl, B.3
  • 53
    • 84858792464 scopus 로고    scopus 로고
    • A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis
    • doi: 10.1038/emboj.2012.26
    • Arac, D., Boucard, A. A., Bolliger, M. F., Nbuyen, J., Soltis, M., Südhof, T. C., and Brunger, A. T. (2012) A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis. EMBO J. doi: 10.1038/emboj.2012.26
    • (2012) EMBO J.
    • Arac, D.1    Boucard, A.A.2    Bolliger, M.F.3    Nbuyen, J.4    Soltis, M.5    Südhof, T.C.6    Brunger, A.T.7


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