Correction: Adhesion G protein-coupled receptors are activated by exposure of a cryptic tethered agonist (Proceedings of the National Academy of Sciences of the United States of America (2015) 112 (6194-6199) DOI: 10.1073/pnas.1421785112);Adhesion G protein-coupled receptors are activated by exposure of a cryptic tethered agonist

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 19, 2015, Pages 6194-6199

  Stoveken, Hannah M ^a   Hajduczok, Alexander G ^a   Xu, Lei ^a   Tall, Gregory G ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

Adhesion; G proteins; GPR110; GPR56; Tethered agonist

Indexed keywords

ADHESION G PROTEIN COUPLED RECEPTOR; ADHESION G PROTEIN COUPLED RECEPTOR 110; ADHESION G PROTEIN COUPLED RECEPTOR 56; G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; SYNTHETIC PEPTIDE; UNCLASSIFIED DRUG; GPR110 PROTEIN, HUMAN; GPR56 PROTEIN, HUMAN; LIGAND; ONCOPROTEIN; PEPTIDE; PROTEIN BINDING;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING KINETICS; BIOCHEMISTRY; DISSOCIATION; EXTRACELLULAR MATRIX; HUMAN; IN VITRO STUDY; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN INDUCTION; AMINO ACID SEQUENCE; ANIMAL; BINDING SITE; CELL ADHESION; CELL LINE; CHEMICAL STRUCTURE; CHEMISTRY; HEK293 CELL LINE; INSECT; METABOLISM; MOLECULAR GENETICS; PROTEIN TERTIARY STRUCTURE; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CELL ADHESION; CELL LINE; HEK293 CELLS; HUMANS; INSECTS; LIGANDS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; ONCOGENE PROTEINS; PEPTIDES; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, G-PROTEIN-COUPLED; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION;

EID: 84929208101     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1510107112     Document Type: Erratum

References (28)

1. Bjarnadóttir TK, et al. (2004) The human and mouse repertoire of the adhesion family of G-protein-coupled receptors. Genomics 84(1):23-33.
2. Langenhan T, Aust G, Hamann J (2013) Sticky signaling-adhesion class G proteincoupled receptors take the stage. Sci Signal 6(276):re3.
3. Paavola KJ, Hall RA (2012) Adhesion G protein-coupled receptors: Signaling, pharmacology, and mechanisms of activation. Mol Pharmacol 82(5):777-783.
4. Aust G (2010) Adhesion-GPCRs in tumorigenesis. Adv Exp Med Biol 706:109-120.
5. Lum AM, et al. (2010) Orphan receptor GPR110, an oncogene overexpressed in lung and prostate cancer. BMC Cancer 10(1):40.
6. Piao X, et al. (2004) G protein-coupled receptor-dependent development of human frontal cortex. Science 303(5666):2033-2036.
7. Yang L, Xu L (2012) GPR56 in cancer progression: Current status and future perspective. Future Oncol 8(4):431-440.
8. Araç D, et al. (2012) A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis. EMBO J 31(6):1364-1378.
9. Prömel S, Langenhan T, Araç D (2013) Matching structure with function: The GAIN domain of adhesion-GPCR and PKD1-like proteins. Trends Pharmacol Sci 34(8):470-478.
10. Luo R, et al. (2011) G protein-coupled receptor 56 and collagen III, a receptor-ligand pair, regulates cortical development and lamination. Proc Natl Acad Sci USA 108(31): 12925-12930.
11. Paavola KJ, Sidik H, Zuchero JB, Eckart M, Talbot WS (2014) Type IV collagen is an activating ligand for the adhesion G protein-coupled receptor GPR126. Sci Signal 7(338):ra76.
12. Paavola KJ, Stephenson JR, Ritter SL, Alter SP, Hall RA (2011) The N terminus of the adhesion G protein-coupled receptor GPR56 controls receptor signaling activity. J Biol Chem 286(33):28914-28921.
13. Xu L, Begum S, Hearn JD, Hynes RO (2006) GPR56, an atypical G protein-coupled receptor, binds tissue transglutaminase, TG2, and inhibits melanoma tumor growth and metastasis. Proc Natl Acad Sci USA 103(24):9023-9028.
14. Prömel S, et al. (2012) Characterization and functional study of a cluster of four highly conserved orphan adhesion-GPCR in mouse. Dev Dyn 241(10):1591-1602.
15. Vu T-KH, Hung DT, Wheaton VI, Coughlin SR (1991) Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation. Cell 64(6):1057-1068.
16. Iguchi T, et al. (2008) Orphan G protein-coupled receptor GPR56 regulates neural progenitor cell migration via a G α 12/13 and Rho pathway. J Biol Chem 283(21):14469-14478.
17. Shashidhar S, et al. (2005) GPR56 is a GPCR that is overexpressed in gliomas and functions in tumor cell adhesion. Oncogene 24(10):1673-1682.
18. Wu MP, et al. (2013) G-protein coupled receptor 56 promotes myoblast fusion through serum response factor- and nuclear factor of activated T-cell-mediated signalling but is not essential for muscle development in vivo. FEBS J 280(23):6097-6113.
19. Bradshaw RA, Brickey WW, Walker KW (1998) N-terminal processing: The methionine aminopeptidase and N α-acetyl transferase families. Trends Biochem Sci 23(7):263-267.
20. Zhang C, et al. (2012) High-resolution crystal structure of human protease-activated receptor 1. Nature 492(7429):387-392.
21. Jin Z, et al. (2007) Disease-associated mutations affect GPR56 protein trafficking and cell surface expression. Hum Mol Genet 16(16):1972-1985.
22. Promel S, et al. (2012) Characterization and functional study of a cluster of four highly conserved orphan adhesion-GPCR in mouse. Dev Dyn 241(10):1591-1602.
23. Chan P, et al. (2011) Purification of heterotrimeric G protein alpha subunits by GST- Ric-8 association: Primary characterization of purified G alpha(olf). J Biol Chem 286(4): 2625-2635.
24. Kozasa T (1999) Purification of Recombinant G Protein α and βγ Subunits from Sf9 Cells (CRC, Boca Raton, FL), pp 23-38.
25. Kozasa T, Gilman AG (1995) Purification of recombinant G proteins from Sf9 cells by hexahistidine tagging of associated subunits. Characterization of alpha 12 and inhibition of adenylyl cyclase by alpha z. J Biol Chem 270(4):1734-1741.
26. Oner SS, Blumer JB, Lanier SM (2013) Group II activators of G-protein signaling: Monitoring the interaction of Gα with the G-protein regulatory motif in the intact cell. Methods Enzymol 522:153-167.
27. Dyer BW, Ferrer FA, Klinedinst DK, Rodriguez R (2000) A noncommercial dual luciferase enzyme assay system for reporter gene analysis. Anal Biochem 282(1):158-161.
28. Chou PY, Fasman GD (1974) Prediction of protein conformation. Biochemistry 13(2): 222-245.