-
1
-
-
61849153021
-
Impact of nanotechnology on drug delivery
-
Farokhzad, O. C. & Langer, R. Impact of nanotechnology on drug delivery. ACS Nano 3, 16-20 (2009).
-
(2009)
ACS Nano
, vol.3
, pp. 16-20
-
-
Farokhzad, O.C.1
Langer, R.2
-
2
-
-
36849067019
-
Nanocarriers as an emerging platform for cancer therapy
-
Peer, D. et al. Nanocarriers as an emerging platform for cancer therapy. Nat. Nanotechnol. 2, 751-760 (2007).
-
(2007)
Nat. Nanotechnol.
, vol.2
, pp. 751-760
-
-
Peer, D.1
-
3
-
-
84855961163
-
Nanoparticle delivery of cancer drugs
-
Wang, A. Z., Langer, R. & Farokhzad, O. C. Nanoparticle delivery of cancer drugs. Annu. Rev. Med. 63, 185-198 (2012).
-
(2012)
Annu. Rev. Med.
, vol.63
, pp. 185-198
-
-
Wang, A.Z.1
Langer, R.2
Farokhzad, O.C.3
-
4
-
-
39649092973
-
Nanotechnology and cancer
-
Heath, J. R. & Davis, M. E. Nanotechnology and cancer. Annu. Rev. Med. 59, 251-265 (2008).
-
(2008)
Annu. Rev. Med.
, vol.59
, pp. 251-265
-
-
Heath, J.R.1
Davis, M.E.2
-
5
-
-
51049090204
-
Nanoparticle therapeutics: An emerging treatment modality for cancer
-
Davis, M. E., Chen, Z. G. & Shin, D. M. Nanoparticle therapeutics: an emerging treatment modality for cancer. Nat. Rev. Drug Discov. 7, 771-782 (2008).
-
(2008)
Nat. Rev. Drug Discov.
, vol.7
, pp. 771-782
-
-
Davis, M.E.1
Chen, Z.G.2
Shin, D.M.3
-
6
-
-
79960363229
-
More effective nanomedicines through particle design
-
Wang, J., Byrne, J. D., Napier, M. E. & DeSimone, J. M. More effective nanomedicines through particle design. Small 7, 1919-1931 (2011).
-
(2011)
Small
, vol.7
, pp. 1919-1931
-
-
Wang, J.1
Byrne, J.D.2
Napier, M.E.3
DeSimone, J.M.4
-
7
-
-
79960356052
-
Beauty is skin deep: A surface monolayer perspective on nanoparticle interactions with cells and bio-macromolecules
-
Saha, K., Bajaj, A., Duncan, B. & Rotello, V. M. Beauty is skin deep: a surface monolayer perspective on nanoparticle interactions with cells and bio-macromolecules. Small 7, 1903-1918 (2011).
-
(2011)
Small
, vol.7
, pp. 1903-1918
-
-
Saha, K.1
Bajaj, A.2
Duncan, B.3
Rotello, V.M.4
-
8
-
-
84906242121
-
Chemical basis of interactions between engineered nanoparticles and biological systems
-
Mu, Q. et al. Chemical basis of interactions between engineered nanoparticles and biological systems. Chem. Rev. 114, 7740-7781 (2014).
-
(2014)
Chem. Rev.
, vol.114
, pp. 7740-7781
-
-
Mu, Q.1
-
9
-
-
84903486219
-
Secreted biomolecules alter the biological identity and cellular interactions of nanoparticles
-
Albanese, A. et al. Secreted biomolecules alter the biological identity and cellular interactions of nanoparticles. ACS Nano 8, 5515-5526 (2014).
-
(2014)
ACS Nano
, vol.8
, pp. 5515-5526
-
-
Albanese, A.1
-
10
-
-
67649491055
-
Understanding biophysicochemical interactions at the nano-bio interface
-
Nel, A. E. et al. Understanding biophysicochemical interactions at the nano-bio interface. Nat. Mater. 8, 543-557 (2009).
-
(2009)
Nat. Mater.
, vol.8
, pp. 543-557
-
-
Nel, A.E.1
-
11
-
-
50149110878
-
The effect of particle design on cellular internalization pathways
-
Gratton, S. E. et al. The effect of particle design on cellular internalization pathways. Proc. Natl Acad. Sci. USA 105, 11613-11618 (2008).
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 11613-11618
-
-
Gratton, S.E.1
-
12
-
-
84858652159
-
Targeted polymeric therapeutic nanoparticles: Design, development and clinical translation
-
Kamaly, N., Xiao, Z., Valencia, P. M., Radovic-Moreno, A. F. & Farokhzad, O. C. Targeted polymeric therapeutic nanoparticles: design, development and clinical translation. Chem. Soc. Rev. 41, 2971-3010 (2012).
-
(2012)
Chem. Soc. Rev.
, vol.41
, pp. 2971-3010
-
-
Kamaly, N.1
Xiao, Z.2
Valencia, P.M.3
Radovic-Moreno, A.F.4
Farokhzad, O.C.5
-
13
-
-
84955607551
-
Impact of particle elasticity on particle-based drug delivery systems
-
Anselmo, A. C. & Mitragotri, S. Impact of particle elasticity on particle-based drug delivery systems. Adv. Drug Deliv. Rev. http://dx. doi. org/10. 1016/ j. addr. 2016. 01. 007 (2016).
-
(2016)
Adv. Drug Deliv. Rev.
-
-
Anselmo, A.C.1
Mitragotri, S.2
-
14
-
-
0017910704
-
Nanoparticles - a new colloidal drug delivery system
-
Marty, J. J., Oppenheim, R. C. & Speiser, P. Nanoparticles - a new colloidal drug delivery system. Pharm. Acta Helv. 53, 17-23 (1978).
-
(1978)
Pharm. Acta Helv.
, vol.53
, pp. 17-23
-
-
Marty, J.J.1
Oppenheim, R.C.2
Speiser, P.3
-
15
-
-
80054741757
-
Self-assembled targeted nanoparticles: Evolution of technologies and bench to bedside translation
-
Shi, J., Xiao, Z., Kamaly, N. & Farokhzad, O. C. Self-assembled targeted nanoparticles: evolution of technologies and bench to bedside translation. Acc. Chem. Res. 44, 1123-1134 (2011).
-
(2011)
Acc. Chem. Res.
, vol.44
, pp. 1123-1134
-
-
Shi, J.1
Xiao, Z.2
Kamaly, N.3
Farokhzad, O.C.4
-
16
-
-
84960532596
-
Nanochemistry and nanomedicine for nanoparticle-based diagnostics and therapy
-
Chen, G., Roy, I., Yang, C. & Prasad, P. N. Nanochemistry and nanomedicine for nanoparticle-based diagnostics and therapy. Chem. Rev. 116, 2826-2885 (2016).
-
(2016)
Chem. Rev.
, vol.116
, pp. 2826-2885
-
-
Chen, G.1
Roy, I.2
Yang, C.3
Prasad, P.N.4
-
17
-
-
75749093027
-
Emerging applications of stimuli-responsive polymer materials
-
Stuart, M. A. et al. Emerging applications of stimuli-responsive polymer materials. Nat. Mater. 9, 101-113 (2010).
-
(2010)
Nat. Mater.
, vol.9
, pp. 101-113
-
-
Stuart, M.A.1
-
18
-
-
84923169388
-
Programmable nanomedicine: Synergistic and sequential drug delivery systems
-
Pacardo, D. B., Ligler, F. S. & Gu, Z. Programmable nanomedicine: synergistic and sequential drug delivery systems. Nanoscale 7, 3381-3391 (2015).
-
(2015)
Nanoscale
, vol.7
, pp. 3381-3391
-
-
Pacardo, D.B.1
Ligler, F.S.2
Gu, Z.3
-
19
-
-
84886292840
-
Stimuli-responsive nanocarriers for drug delivery
-
Mura, S., Nicolas, J. & Couvreur, P. Stimuli-responsive nanocarriers for drug delivery. Nat. Mater. 12, 991-1003 (2013).
-
(2013)
Nat. Mater.
, vol.12
, pp. 991-1003
-
-
Mura, S.1
Nicolas, J.2
Couvreur, P.3
-
20
-
-
84929073061
-
Stimulus-responsive hydrogels: Theory, modern advances, and applications
-
Koetting, M. C., Peters, J. T., Steichen, S. D. & Peppas, N. A. Stimulus-responsive hydrogels: theory, modern advances, and applications. Mater. Sci. Eng. R. Rep. 93, 1-49 (2015).
-
(2015)
Mater. Sci. Eng. R. Rep.
, vol.93
, pp. 1-49
-
-
Koetting, M.C.1
Peters, J.T.2
Steichen, S.D.3
Peppas, N.A.4
-
21
-
-
84908501841
-
Multifunctional, stimuli-sensitive nanoparticulate systems for drug delivery
-
Torchilin, V. P. Multifunctional, stimuli-sensitive nanoparticulate systems for drug delivery. Nat. Rev. Drug Discov. 13, 813-827 (2014).
-
(2014)
Nat. Rev. Drug Discov.
, vol.13
, pp. 813-827
-
-
Torchilin, V.P.1
-
22
-
-
84864527570
-
Enzyme-responsive nanoparticles for drug release and diagnostics
-
de la Rica, R., Aili, D. & Stevens, M. M. Enzyme-responsive nanoparticles for drug release and diagnostics. Adv. Drug Deliv. Rev. 64, 967-978 (2012).
-
(2012)
Adv. Drug Deliv. Rev.
, vol.64
, pp. 967-978
-
-
De La Rica, R.1
Aili, D.2
Stevens, M.M.3
-
23
-
-
84961844230
-
Engineering nanolayered particles for modular drug delivery
-
Correa, S., Dreaden, E. C., Gu, L. & Hammond, P. T. Engineering nanolayered particles for modular drug delivery. J. Control. Release 240, 364-386 (2016).
-
(2016)
J. Control. Release
, vol.240
, pp. 364-386
-
-
Correa, S.1
Dreaden, E.C.2
Gu, L.3
Hammond, P.T.4
-
24
-
-
84958708219
-
"Combo" nanomedicine: Co-delivery of multi-modal therapeutics for efficient, targeted, and safe cancer therapy
-
Kemp, J. A., Shim, M. S., Heo, C. Y. & Kwon, Y. J. "Combo" nanomedicine: co-delivery of multi-modal therapeutics for efficient, targeted, and safe cancer therapy. Adv. Drug Deliv. Rev. 98, 3-18 (2016).
-
(2016)
Adv. Drug Deliv. Rev.
, vol.98
, pp. 3-18
-
-
Kemp, J.A.1
Shim, M.S.2
Heo, C.Y.3
Kwon, Y.J.4
-
25
-
-
84925769724
-
Cancer nanomedicine: From targeted delivery to combination therapy
-
Xu, X., Ho, W., Zhang, X., Bertrand, N. & Farokhzad, O. Cancer nanomedicine: from targeted delivery to combination therapy. Trends Mol. Med. 21, 223-232 (2015).
-
(2015)
Trends Mol. Med.
, vol.21
, pp. 223-232
-
-
Xu, X.1
Ho, W.2
Zhang, X.3
Bertrand, N.4
Farokhzad, O.5
-
26
-
-
84877120847
-
First-in-humans trial of an RNA interference therapeutic targeting VEGF and KSP in cancer patients with liver involvement
-
Tabernero, J. et al. First-in-humans trial of an RNA interference therapeutic targeting VEGF and KSP in cancer patients with liver involvement. Cancer Discov. 3, 406-417 (2013).
-
(2013)
Cancer Discov.
, vol.3
, pp. 406-417
-
-
Tabernero, J.1
-
27
-
-
81355149640
-
Nanotechnology for therapy and imaging of liver diseases
-
Reddy, L. H. & Couvreur, P. Nanotechnology for therapy and imaging of liver diseases. J. Hepatol. 55, 1461-1466 (2011).
-
(2011)
J. Hepatol.
, vol.55
, pp. 1461-1466
-
-
Reddy, L.H.1
Couvreur, P.2
-
28
-
-
47949120334
-
Biofunctionalized targeted nanoparticles for therapeutic applications
-
Wang, A. Z. et al. Biofunctionalized targeted nanoparticles for therapeutic applications. Expert Opin. Biol. Ther. 8, 1063-1070 (2008).
-
(2008)
Expert Opin. Biol. Ther.
, vol.8
, pp. 1063-1070
-
-
Wang, A.Z.1
-
29
-
-
84885087763
-
Pegylated liposomal doxorubicin: A guide to its use in various malignancies
-
Lyseng-Williamson, K. A., Duggan, S. T. & Keating, G. M. Pegylated liposomal doxorubicin: a guide to its use in various malignancies. BioDrugs 27, 533-540 (2013).
-
(2013)
BioDrugs
, vol.27
, pp. 533-540
-
-
Lyseng-Williamson, K.A.1
Duggan, S.T.2
Keating, G.M.3
-
30
-
-
84861669644
-
Doxil® - the first FDA-approved nano-drug: Lessons learned
-
Barenholz, Y. Doxil® - the first FDA-approved nano-drug: lessons learned. J. Control. Release 160, 117-134 (2012).
-
(2012)
J. Control. Release
, vol.160
, pp. 117-134
-
-
Barenholz, Y.1
-
31
-
-
0028937391
-
Liposomal-entrapped doxorubicin: An active agent in AIDS-related Kaposi's sarcoma
-
Harrison, M., Tomlinson, D. & Stewart, S. Liposomal-entrapped doxorubicin: an active agent in AIDS-related Kaposi's sarcoma. J. Clin. Oncol. 13, 914-920 (1995).
-
(1995)
J. Clin. Oncol.
, vol.13
, pp. 914-920
-
-
Harrison, M.1
Tomlinson, D.2
Stewart, S.3
-
32
-
-
0027772638
-
Liposomal daunorubicin in advanced Kaposi's sarcoma: A phase II study
-
Money-Kyrle, J. F. et al. Liposomal daunorubicin in advanced Kaposi's sarcoma: a phase II study. Clin. Oncol. 5, 367-371 (1993).
-
(1993)
Clin. Oncol.
, vol.5
, pp. 367-371
-
-
Money-Kyrle, J.F.1
-
33
-
-
0036161926
-
Phase IV study of liposomal daunorubicin (DaunoXome) in AIDS-related Kaposi sarcoma
-
Rosenthal, E. et al. Phase IV study of liposomal daunorubicin (DaunoXome) in AIDS-related Kaposi sarcoma. Am. J. Clin. Oncol. 25, 57-59 (2002).
-
(2002)
Am. J. Clin. Oncol.
, vol.25
, pp. 57-59
-
-
Rosenthal, E.1
-
34
-
-
0032991693
-
Food and Drug Administration approval of AmBisome (liposomal amphotericin B) for treatment of visceral leishmaniasis
-
Meyerhoff, A. U. S. Food and Drug Administration approval of AmBisome (liposomal amphotericin B) for treatment of visceral leishmaniasis. Clin. Infect. Dis. 28, 42-48 (1999).
-
(1999)
Clin. Infect. Dis.
, vol.28
, pp. 42-48
-
-
Meyerhoff, A.U.S.1
-
35
-
-
84880421469
-
Salvage chemotherapy in recurrent platinum-resistant or refractory epithelial ovarian cancer with Carboplatin and distearoylphosphatidylcholine pegylated liposomal Doxorubicin (Lipo-Dox®)
-
Khemapech, N., Oranratanaphan, S., Termrungruanglert, W., Lertkhachonsuk, R. & Vasurattana, A. Salvage chemotherapy in recurrent platinum-resistant or refractory epithelial ovarian cancer with Carboplatin and distearoylphosphatidylcholine pegylated liposomal Doxorubicin (Lipo-Dox®). Asian Pac. J. Cancer Prev. 14, 2131-2135 (2013).
-
(2013)
Asian Pac. J. Cancer Prev.
, vol.14
, pp. 2131-2135
-
-
Khemapech, N.1
Oranratanaphan, S.2
Termrungruanglert, W.3
Lertkhachonsuk, R.4
Vasurattana, A.5
-
36
-
-
0032711629
-
A randomized controlled trial comparing intrathecal sustained-release cytarabine (DepoCyt) to intrathecal methotrexate in patients with neoplastic meningitis from solid tumors
-
Glantz, M. J. et al. A randomized controlled trial comparing intrathecal sustained-release cytarabine (DepoCyt) to intrathecal methotrexate in patients with neoplastic meningitis from solid tumors. Clin. Cancer Res. 5, 3394-3402 (1999).
-
(1999)
Clin. Cancer Res.
, vol.5
, pp. 3394-3402
-
-
Glantz, M.J.1
-
37
-
-
0035282073
-
Reduced cardiotoxicity and preserved antitumor efficacy of liposome-encapsulated doxorubicin and cyclophosphamide compared with conventional doxorubicin and cyclophosphamide in a randomized, multicenter trial of metastatic breast cancer
-
Batist, G. et al. Reduced cardiotoxicity and preserved antitumor efficacy of liposome-encapsulated doxorubicin and cyclophosphamide compared with conventional doxorubicin and cyclophosphamide in a randomized, multicenter trial of metastatic breast cancer. J. Clin. Oncol. 19, 1444-1454 (2001).
-
(2001)
J. Clin. Oncol.
, vol.19
, pp. 1444-1454
-
-
Batist, G.1
-
38
-
-
84864396563
-
Pharmacogenetics of antiangiogenic and antineovascular therapies of age-related macular degeneration
-
Agosta, E. et al. Pharmacogenetics of antiangiogenic and antineovascular therapies of age-related macular degeneration. Pharmacogenomics 13, 1037-1053 (2012).
-
(2012)
Pharmacogenomics
, vol.13
, pp. 1037-1053
-
-
Agosta, E.1
-
39
-
-
38049019767
-
An open-label study to evaluate dose and cycle dependence of the pharmacokinetics of pegylated liposomal doxorubicin
-
Gabizon, A. et al. An open-label study to evaluate dose and cycle dependence of the pharmacokinetics of pegylated liposomal doxorubicin. Cancer Chemother. Pharmacol. 61, 695-702 (2008).
-
(2008)
Cancer Chemother. Pharmacol.
, vol.61
, pp. 695-702
-
-
Gabizon, A.1
-
40
-
-
15544384465
-
A comparison of Depodur, a novel, single-dose extended-release epidural morphine, with standard epidural morphine for pain relief after lower abdominal surgery
-
Gambling, D., Hughes, T., Martin, G., Horton, W. & Manvelian, G. A comparison of Depodur, a novel, single-dose extended-release epidural morphine, with standard epidural morphine for pain relief after lower abdominal surgery. Anesth. Analg. 100, 1065-1074 (2005).
-
(2005)
Anesth. Analg.
, vol.100
, pp. 1065-1074
-
-
Gambling, D.1
Hughes, T.2
Martin, G.3
Horton, W.4
Manvelian, G.5
-
41
-
-
84901298246
-
Pharmacokinetics and pharmacodynamics of liposomal mifamurtide in adult volunteers with mild or moderate hepatic impairment
-
Venkatakrishnan, K. et al. Pharmacokinetics and pharmacodynamics of liposomal mifamurtide in adult volunteers with mild or moderate hepatic impairment. Br. J. Clin. Pharmacol. 77, 998-1010 (2014).
-
(2014)
Br. J. Clin. Pharmacol.
, vol.77
, pp. 998-1010
-
-
Venkatakrishnan, K.1
-
42
-
-
84868228216
-
FDA approves liposomal vincristine (Marqibo) for rare leukemia
-
Ingram, I. FDA approves liposomal vincristine (Marqibo) for rare leukemia. Oncology (Williston Park) 26, 841 (2012).
-
(2012)
Oncology (Williston Park)
, vol.26
, pp. 841
-
-
Ingram, I.1
-
43
-
-
84875873258
-
Marqibo® (vincristine sulfate liposome injection) improves the pharmacokinetics and pharmacodynamics of vincristine
-
Silverman, J. A. & Deitcher, S. R. Marqibo® (vincristine sulfate liposome injection) improves the pharmacokinetics and pharmacodynamics of vincristine. Cancer Chemother. Pharmacol. 71, 555-564 (2013).
-
(2013)
Cancer Chemother. Pharmacol.
, vol.71
, pp. 555-564
-
-
Silverman, J.A.1
Deitcher, S.R.2
-
44
-
-
84873252557
-
Liposomal drug delivery systems: From concept to clinical applications
-
Allen, T. M. & Cullis, P. R. Liposomal drug delivery systems: from concept to clinical applications. Adv. Drug Deliv. Rev. 65, 36-48 (2013).
-
(2013)
Adv. Drug Deliv. Rev.
, vol.65
, pp. 36-48
-
-
Allen, T.M.1
Cullis, P.R.2
-
45
-
-
0037681850
-
Pharmacokinetics of pegylated liposomal doxorubicin: Review of animal and human studies
-
Gabizon, A., Shmeeda, H. & Barenholz, Y. Pharmacokinetics of pegylated liposomal doxorubicin: review of animal and human studies. Clin. Pharmacokinet. 42, 419-436 (2003).
-
(2003)
Clin. Pharmacokinet.
, vol.42
, pp. 419-436
-
-
Gabizon, A.1
Shmeeda, H.2
Barenholz, Y.3
-
46
-
-
56949084877
-
Albumin as a drug carrier: Design of prodrugs, drug conjugates and nanoparticles
-
Kratz, F. Albumin as a drug carrier: design of prodrugs, drug conjugates and nanoparticles. J. Control. Release 132, 171-183 (2008).
-
(2008)
J. Control. Release
, vol.132
, pp. 171-183
-
-
Kratz, F.1
-
47
-
-
0037139411
-
Paclitaxel and its formulations
-
Singla, A. K., Garg, A. & Aggarwal, D. Paclitaxel and its formulations. Int. J. Pharm. 235, 179-192 (2002).
-
(2002)
Int. J. Pharm.
, vol.235
, pp. 179-192
-
-
Singla, A.K.1
Garg, A.2
Aggarwal, D.3
-
48
-
-
84941888689
-
Albumin-bound paclitaxel in solid tumors: Clinical development and future directions
-
Kundranda, M. N. & Niu, J. Albumin-bound paclitaxel in solid tumors: clinical development and future directions. Drug Des. Devel. Ther. 9, 3767-3777 (2015).
-
(2015)
Drug Des. Devel. Ther.
, vol.9
, pp. 3767-3777
-
-
Kundranda, M.N.1
Niu, J.2
-
49
-
-
84959421154
-
Simple bioconjugate chemistry serves great clinical advances: Albumin as a versatile platform for diagnosis and precision therapy
-
Liu, Z. & Chen, X. Simple bioconjugate chemistry serves great clinical advances: albumin as a versatile platform for diagnosis and precision therapy. Chem. Soc. Rev. 45, 1432-1456 (2016).
-
(2016)
Chem. Soc. Rev.
, vol.45
, pp. 1432-1456
-
-
Liu, Z.1
Chen, X.2
-
50
-
-
24944505659
-
Multicenter phase II trial of ABI-007, an albumin-bound paclitaxel, in women with metastatic breast cancer
-
Ibrahim, N. K. et al. Multicenter phase II trial of ABI-007, an albumin-bound paclitaxel, in women with metastatic breast cancer. J. Clin. Oncol. 23, 6019-6026 (2005).
-
(2005)
J. Clin. Oncol.
, vol.23
, pp. 6019-6026
-
-
Ibrahim, N.K.1
-
51
-
-
84979273487
-
Superior therapeutic efficacy of nab-paclitaxel over cremophor-based paclitaxel in locally advanced and metastatic models of human pancreatic cancer
-
Rajeshkumar, N. V. et al. Superior therapeutic efficacy of nab-paclitaxel over cremophor-based paclitaxel in locally advanced and metastatic models of human pancreatic cancer. Br. J. Cancer 115, 442-453 (2016).
-
(2016)
Br. J. Cancer
, vol.115
, pp. 442-453
-
-
Rajeshkumar, N.V.1
-
52
-
-
16544373481
-
A multi-center, late phase II clinical trial of Genexol (paclitaxel) and cisplatin for patients with advanced gastric cancer
-
Park, S. R. et al. A multi-center, late phase II clinical trial of Genexol (paclitaxel) and cisplatin for patients with advanced gastric cancer. Oncol. Rep. 12, 1059-1064 (2004).
-
(2004)
Oncol. Rep.
, vol.12
, pp. 1059-1064
-
-
Park, S.R.1
-
53
-
-
2542559832
-
Phase i and pharmacokinetic study of Genexol-PM, a cremophor-free, polymeric micelle-formulated paclitaxel, in patients with advanced malignancies
-
Kim, T. Y. et al. Phase I and pharmacokinetic study of Genexol-PM, a cremophor-free, polymeric micelle-formulated paclitaxel, in patients with advanced malignancies. Clin. Cancer Res. 10, 3708-3716 (2004).
-
(2004)
Clin. Cancer Res.
, vol.10
, pp. 3708-3716
-
-
Kim, T.Y.1
-
54
-
-
84906789102
-
Multi-layered nanoparticles for combination gene and drug delivery to tumors
-
Ediriwickrema, A., Zhou, J., Deng, Y. & Saltzman, W. M. Multi-layered nanoparticles for combination gene and drug delivery to tumors. Biomaterials 35, 9343-9354 (2014).
-
(2014)
Biomaterials
, vol.35
, pp. 9343-9354
-
-
Ediriwickrema, A.1
Zhou, J.2
Deng, Y.3
Saltzman, W.M.4
-
55
-
-
84938789221
-
Core-crosslinked polymeric micelles: Principles, preparation, biomedical applications and clinical translation
-
Talelli, M. et al. Core-crosslinked polymeric micelles: principles, preparation, biomedical applications and clinical translation. Nano Today 10, 93-117 (2015).
-
(2015)
Nano Today
, vol.10
, pp. 93-117
-
-
Talelli, M.1
-
56
-
-
84978795879
-
Development of polymeric micelles for targeting intractable cancers
-
Nishiyama, N., Matsumura, Y. & Kataoka, K. Development of polymeric micelles for targeting intractable cancers. Cancer Sci. 107, 867-874 (2016).
-
(2016)
Cancer Sci.
, vol.107
, pp. 867-874
-
-
Nishiyama, N.1
Matsumura, Y.2
Kataoka, K.3
-
57
-
-
84906786049
-
Progress of drug-loaded polymeric micelles into clinical studies
-
Cabral, H. & Kataoka, K. Progress of drug-loaded polymeric micelles into clinical studies. J. Control. Release 190, 465-476 (2014).
-
(2014)
J. Control. Release
, vol.190
, pp. 465-476
-
-
Cabral, H.1
Kataoka, K.2
-
58
-
-
49749101644
-
Pluronic block copolymers: Evolution of drug delivery concept from inert nanocarriers to biological response modifiers
-
Batrakova, E. V. & Kabanov, A. V. Pluronic block copolymers: evolution of drug delivery concept from inert nanocarriers to biological response modifiers. J. Control. Release 130, 98-106 (2008).
-
(2008)
J. Control. Release
, vol.130
, pp. 98-106
-
-
Batrakova, E.V.1
Kabanov, A.V.2
-
59
-
-
60749108001
-
Polymeric drugs for efficient tumor-targeted drug delivery based on EPR-effect
-
Maeda, H., Bharate, G. Y. & Daruwalla J. Polymeric drugs for efficient tumor-targeted drug delivery based on EPR-effect. Eur. J. Pharm. Biopharm 71, 409-419 (2009).
-
(2009)
Eur. J. Pharm. Biopharm
, vol.71
, pp. 409-419
-
-
Maeda, H.1
Bharate, G.Y.2
Daruwalla, J.3
-
60
-
-
0033629139
-
Comparison of action of paclitaxel and poly(L-glutamic acid)-paclitaxel conjugate in human breast cancer cells
-
Oldham, E. A. Li, C., Ke, S., Wallace, S. & Huang, P. Comparison of action of paclitaxel and poly(L-glutamic acid)-paclitaxel conjugate in human breast cancer cells. Int. J. Oncol. 16, 125-132 (2000).
-
(2000)
Int. J. Oncol.
, vol.16
, pp. 125-132
-
-
Oldham, E.A.1
Li, C.2
Ke, S.3
Wallace, S.4
Huang, P.5
-
61
-
-
84906781816
-
Polymer therapeutics: Top 10 selling pharmaceuticals - what next? J
-
Duncan, R. Polymer therapeutics: top 10 selling pharmaceuticals - what next? J. Control. Release 190, 371-380 (2014).
-
(2014)
Control. Release
, vol.190
, pp. 371-380
-
-
Duncan, R.1
-
62
-
-
33747840618
-
Polymer conjugates as anticancer nanomedicines
-
Duncan, R. Polymer conjugates as anticancer nanomedicines. Nat. Rev. Cancer 6, 688-701 (2006).
-
(2006)
Nat. Rev. Cancer
, vol.6
, pp. 688-701
-
-
Duncan, R.1
-
63
-
-
84962052506
-
Dual HER2 targeting with trastuzumab and liposomal-encapsulated doxorubicin (MM-302) demonstrates synergistic antitumor activity in breast and gastric cancer
-
Espelin, C. W., Leonard, S. C., Geretti, E., Wickham, T. J. & Hendriks, B. S. Dual HER2 targeting with trastuzumab and liposomal-encapsulated doxorubicin (MM-302) demonstrates synergistic antitumor activity in breast and gastric cancer. Cancer Res. 76, 1517-1527 (2016).
-
(2016)
Cancer Res.
, vol.76
, pp. 1517-1527
-
-
Espelin, C.W.1
Leonard, S.C.2
Geretti, E.3
Wickham, T.J.4
Hendriks, B.S.5
-
64
-
-
84858665432
-
Preclinical development and clinical translation of a PSMA-targeted docetaxel nanoparticle with a differentiated pharmacological profile
-
Hrkach, J. et al. Preclinical development and clinical translation of a PSMA-targeted docetaxel nanoparticle with a differentiated pharmacological profile. Sci. Transl Med. 4, 128ra139 (2012).
-
(2012)
Sci. Transl Med.
, vol.4
, pp. 128ra139
-
-
Hrkach, J.1
-
65
-
-
77951132901
-
Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles
-
Davis, M. E. et al. Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles. Nature 464, 1067-1070 (2010).
-
(2010)
Nature
, vol.464
, pp. 1067-1070
-
-
Davis, M.E.1
-
66
-
-
84995449365
-
Final results of a phase III randomized trial of CPX-351 versus 7+3 in older patients with newly diagnosed high risk (secondary) AML
-
Lancet, J. E. Final results of a phase III randomized trial of CPX-351 versus 7+3 in older patients with newly diagnosed high risk (secondary) AML. J. Clin. Oncol. 34 (Suppl.), 7000 (2016).
-
(2016)
J. Clin. Oncol.
, vol.34
, pp. 7000
-
-
Lancet, J.E.1
-
67
-
-
84911990896
-
Emerging concepts in dendrimer-based nanomedicine: From design principles to clinical applications
-
Kannan, R. M., Nance, E., Kannan, S. & Tomalia, D. A. Emerging concepts in dendrimer-based nanomedicine: from design principles to clinical applications. J. Intern. Med. 276, 579-617 (2014).
-
(2014)
J. Intern. Med.
, vol.276
, pp. 579-617
-
-
Kannan, R.M.1
Nance, E.2
Kannan, S.3
Tomalia, D.A.4
-
68
-
-
84949654506
-
The potential of HIV-1 nanotherapeutics: From in vitro studies to clinical trials
-
Roy, U. et al. The potential of HIV-1 nanotherapeutics: from in vitro studies to clinical trials. Nanomedicine (Lond.) 10, 3597-3609 (2015).
-
(2015)
Nanomedicine (Lond.)
, vol.10
, pp. 3597-3609
-
-
Roy, U.1
-
69
-
-
84885386826
-
Expand classical drug administration ways by emerging routes using dendrimer drug delivery systems: A concise overview
-
Mignani, S., El Kazzouli, S., Bousmina, M. & Majoral, J. P. Expand classical drug administration ways by emerging routes using dendrimer drug delivery systems: a concise overview. Adv. Drug Deliv. Rev. 65, 1316-1330 (2013).
-
(2013)
Adv. Drug Deliv. Rev.
, vol.65
, pp. 1316-1330
-
-
Mignani, S.1
El Kazzouli, S.2
Bousmina, M.3
Majoral, J.P.4
-
70
-
-
79959462226
-
Beating cancer in multiple ways using nanogold
-
Dreaden, E. C., Mackey, M. A., Huang, X., Kang, B. & El-Sayed, M. A. Beating cancer in multiple ways using nanogold. Chem. Soc. Rev. 40, 3391-3404 (2011).
-
(2011)
Chem. Soc. Rev.
, vol.40
, pp. 3391-3404
-
-
Dreaden, E.C.1
Mackey, M.A.2
Huang, X.3
Kang, B.4
El-Sayed, M.A.5
-
71
-
-
84939575307
-
Review of clinical translation of inorganic nanoparticles
-
Anselmo, A. C. & Mitragotri, S. A. Review of clinical translation of inorganic nanoparticles. AAPS J. 17, 1041-1054 (2015).
-
(2015)
AAPS J.
, vol.17
, pp. 1041-1054
-
-
Anselmo, A.C.1
Mitragotri, S.A.2
-
72
-
-
77951683095
-
Gold nanoparticles for biology and medicine
-
Giljohann, D. A. et al. Gold nanoparticles for biology and medicine. Angew. Chem. Int. Ed. 49, 3280-3294 (2010).
-
(2010)
Angew. Chem. Int. Ed.
, vol.49
, pp. 3280-3294
-
-
Giljohann, D.A.1
-
73
-
-
84924957528
-
Ultrasonic delivery of silica-gold nanoshells for photothermolysis of sebaceous glands in humans: Nanotechnology from the bench to clinic
-
Paithankar, D. et al. Ultrasonic delivery of silica-gold nanoshells for photothermolysis of sebaceous glands in humans: Nanotechnology from the bench to clinic. J. Control Release 206, 30-36 (2015).
-
(2015)
J. Control Release
, vol.206
, pp. 30-36
-
-
Paithankar, D.1
-
74
-
-
84954288779
-
Advances in silica based nanoparticles for targeted cancer therapy
-
Yang, Y. & Yu, C. Advances in silica based nanoparticles for targeted cancer therapy. Nanomedicine 12, 317-332 (2016).
-
(2016)
Nanomedicine
, vol.12
, pp. 317-332
-
-
Yang, Y.1
Yu, C.2
-
75
-
-
84928939851
-
Use of a lipid-coated mesoporous silica nanoparticle platform for synergistic gemcitabine and paclitaxel delivery to human pancreatic cancer in mice
-
Meng, H. et al. Use of a lipid-coated mesoporous silica nanoparticle platform for synergistic gemcitabine and paclitaxel delivery to human pancreatic cancer in mice. ACS Nano 9, 3540-3557 (2015).
-
(2015)
ACS Nano
, vol.9
, pp. 3540-3557
-
-
Meng, H.1
-
76
-
-
47249140441
-
Magnetic iron oxide nanoparticles: Synthesis, stabilization, vectorization, physicochemical characterizations, and biological applications
-
Laurent, S. et al. Magnetic iron oxide nanoparticles: synthesis, stabilization, vectorization, physicochemical characterizations, and biological applications. Chem. Rev. 108, 2064-2110 (2008).
-
(2008)
Chem. Rev.
, vol.108
, pp. 2064-2110
-
-
Laurent, S.1
-
77
-
-
79959846524
-
Efficacy and safety of intratumoral thermotherapy using magnetic iron-oxide nanoparticles combined with external beam radiotherapy on patients with recurrent glioblastoma multiforme
-
Maier-Hauff, K. et al. Efficacy and safety of intratumoral thermotherapy using magnetic iron-oxide nanoparticles combined with external beam radiotherapy on patients with recurrent glioblastoma multiforme. J. Neurooncol. 103, 317-324 (2011).
-
(2011)
J. Neurooncol.
, vol.103
, pp. 317-324
-
-
Maier-Hauff, K.1
-
78
-
-
84867095663
-
Nanoscale radiotherapy with hafnium oxide nanoparticles
-
Maggiorella, L. et al. Nanoscale radiotherapy with hafnium oxide nanoparticles. Future Oncol. 8, 1167-1181 (2012).
-
(2012)
Future Oncol.
, vol.8
, pp. 1167-1181
-
-
Maggiorella, L.1
-
79
-
-
79961209288
-
Cytotoxicity and physicochemical properties of hafnium oxide nanoparticles
-
Field, J. A. et al. Cytotoxicity and physicochemical properties of hafnium oxide nanoparticles. Chemosphere 84, 1401-1407 (2011).
-
(2011)
Chemosphere
, vol.84
, pp. 1401-1407
-
-
Field, J.A.1
-
80
-
-
78650348824
-
Phase i and pharmacokinetic studies of CYT-6091, a novel PEGylated colloidal gold-rhTNF nanomedicine
-
Libutti, S. K. et al. Phase I and pharmacokinetic studies of CYT-6091, a novel PEGylated colloidal gold-rhTNF nanomedicine. Clin. Cancer Res. 16, 6139-6149 (2010).
-
(2010)
Clin. Cancer Res.
, vol.16
, pp. 6139-6149
-
-
Libutti, S.K.1
-
81
-
-
84907151551
-
Research perspectives: Gold nanoparticles in cancer theranostics
-
Li, J., Gupta, S. & Li, C. Research perspectives: gold nanoparticles in cancer theranostics. Quant. Imaging Med. Surg. 3, 284-291 (2013).
-
(2013)
Quant. Imaging Med. Surg.
, vol.3
, pp. 284-291
-
-
Li, J.1
Gupta, S.2
Li, C.3
-
82
-
-
84887409170
-
Ferumoxtran-10 ultrasmall superparamagnetic iron oxide-enhanced diffusion-weighted imaging magnetic resonance imaging for detection of metastases in normal-sized lymph nodes in patients with bladder and prostate cancer: Do we enter the era after extended pelvic lymph node dissection? Eur
-
Fortuin, A. S., Meijer, H., Thompson, L. C., Witjes, J. A. & Barentsz, J. O. Ferumoxtran-10 ultrasmall superparamagnetic iron oxide-enhanced diffusion-weighted imaging magnetic resonance imaging for detection of metastases in normal-sized lymph nodes in patients with bladder and prostate cancer: do we enter the era after extended pelvic lymph node dissection? Eur. Urol. 64, 961-963 (2013).
-
(2013)
Urol.
, vol.64
, pp. 961-963
-
-
Fortuin, A.S.1
Meijer, H.2
Thompson, L.C.3
Witjes, J.A.4
Barentsz, J.O.5
-
83
-
-
84899148220
-
Enhanced primary tumor delineation in pancreatic adenocarcinoma using ultrasmall super paramagnetic iron oxide nanoparticle-ferumoxytol: An initial experience with histopathologic correlation
-
Hedgire, S. S. et al. Enhanced primary tumor delineation in pancreatic adenocarcinoma using ultrasmall super paramagnetic iron oxide nanoparticle-ferumoxytol: an initial experience with histopathologic correlation. Int. J. Nanomedicine 9, 1891-1896 (2014).
-
(2014)
Int. J. Nanomedicine
, vol.9
, pp. 1891-1896
-
-
Hedgire, S.S.1
-
84
-
-
77953683244
-
Nanopharmacy: Inorganic nanoscale devices as vectors and active compounds
-
Rivera Gil, P., Huhn, D., del Mercato, L. L., Sasse, D. & Parak, W. J. Nanopharmacy: inorganic nanoscale devices as vectors and active compounds. Pharmacol. Res. 62, 115-125 (2010).
-
(2010)
Pharmacol. Res.
, vol.62
, pp. 115-125
-
-
Rivera Gil, P.1
Huhn, D.2
Del Mercato, L.L.3
Sasse, D.4
Parak, W.J.5
-
85
-
-
84896049687
-
A phase 1 study of the BCL2-targeted deoxyribonucleic acid inhibitor (DNAi) PNT2258 in patients with advanced solid tumors
-
Tolcher, A. W. et al. A phase 1 study of the BCL2-targeted deoxyribonucleic acid inhibitor (DNAi) PNT2258 in patients with advanced solid tumors. Cancer Chemother. Pharmacol. 73, 363-371 (2014).
-
(2014)
Cancer Chemother. Pharmacol.
, vol.73
, pp. 363-371
-
-
Tolcher, A.W.1
-
86
-
-
84919724347
-
First-in-human phase i study of the liposomal RNA interference therapeutic Atu027 in patients with advanced solid tumors
-
Schultheis, B. et al. First-in-human phase I study of the liposomal RNA interference therapeutic Atu027 in patients with advanced solid tumors. J. Clin. Oncol. 32, 4141-4148 (2014).
-
(2014)
J. Clin. Oncol.
, vol.32
, pp. 4141-4148
-
-
Schultheis, B.1
-
87
-
-
84890099118
-
Spherical nucleic acid nanoparticle conjugates as an RNAi-based therapy for glioblastoma
-
Jensen, S. A. et al. Spherical nucleic acid nanoparticle conjugates as an RNAi-based therapy for glioblastoma. Sci. Transl Med. 5, 209ra152 (2013).
-
(2013)
Sci. Transl Med.
, vol.5
, pp. 209ra152
-
-
Jensen, S.A.1
-
88
-
-
84947087821
-
Biomaterials for mRNA delivery
-
Islam, M. A. et al. Biomaterials for mRNA delivery. Biomater. Sci. 3, 1519-1533 (2015).
-
(2015)
Biomater. Sci.
, vol.3
, pp. 1519-1533
-
-
Islam, M.A.1
-
89
-
-
84866743713
-
Combination delivery of TGF-? Inhibitor and IL-2 by nanoscale liposomal polymeric gels enhances tumour immunotherapy
-
Park, J. et al. Combination delivery of TGF-? inhibitor and IL-2 by nanoscale liposomal polymeric gels enhances tumour immunotherapy. Nat. Mater. 11, 895-905 (2012).
-
(2012)
Nat. Mater.
, vol.11
, pp. 895-905
-
-
Park, J.1
-
90
-
-
80054681184
-
Targeted chemoimmunotherapy using drug-loaded aptamer-dendrimer bioconjugates
-
Lee, I. H. et al. Targeted chemoimmunotherapy using drug-loaded aptamer-dendrimer bioconjugates. J. Control. Release 155, 435-441 (2011).
-
(2011)
J. Control. Release
, vol.155
, pp. 435-441
-
-
Lee, I.H.1
-
91
-
-
44249100151
-
Use of a targeted oncolytic poxvirus, JX-594, in patients with refractory primary or metastatic liver cancer: A phase i trial
-
Park, B. H. et al. Use of a targeted oncolytic poxvirus, JX-594, in patients with refractory primary or metastatic liver cancer: a phase I trial. Lancet Oncol. 9, 533-542 (2008).
-
(2008)
Lancet Oncol.
, vol.9
, pp. 533-542
-
-
Park, B.H.1
-
92
-
-
82755187264
-
Applications of viral nanoparticles in medicine
-
Yildiz, I., Shukla, S. & Steinmetz, N. F. Applications of viral nanoparticles in medicine. Curr. Opin. Biotechnol. 22, 901-908 (2011).
-
(2011)
Curr. Opin. Biotechnol.
, vol.22
, pp. 901-908
-
-
Yildiz, I.1
Shukla, S.2
Steinmetz, N.F.3
-
93
-
-
84968760260
-
Tobacco mosaic virus delivery of phenanthriplatin for cancer therapy
-
Czapar, A. E. et al. Tobacco mosaic virus delivery of phenanthriplatin for cancer therapy. ACS Nano 10, 4119-4126 (2016).
-
(2016)
ACS Nano
, vol.10
, pp. 4119-4126
-
-
Czapar, A.E.1
-
94
-
-
84859443203
-
The oncolytic poxvirus JX-594 selectively replicates in and destroys cancer cells driven by genetic pathways commonly activated in cancers
-
Parato, K. A. et al. The oncolytic poxvirus JX-594 selectively replicates in and destroys cancer cells driven by genetic pathways commonly activated in cancers. Mol. Ther. 20, 749-758 (2012).
-
(2012)
Mol. Ther.
, vol.20
, pp. 749-758
-
-
Parato, K.A.1
-
95
-
-
84947485402
-
Using exosomes, naturally-equipped nanocarriers, for drug delivery
-
Batrakova, E. V. & Kim, M. S. Using exosomes, naturally-equipped nanocarriers, for drug delivery. J. Control. Release 219, 396-405 (2015).
-
(2015)
J. Control. Release
, vol.219
, pp. 396-405
-
-
Batrakova, E.V.1
Kim, M.S.2
-
96
-
-
84991279024
-
Renal extracellular vesicles: From physiology to clinical application
-
Morrison, E. E., Bailey, M. A. & Dear, J. W. Renal extracellular vesicles: from physiology to clinical application. J. Physiol. 594, 5735-5748 (2016).
-
(2016)
J. Physiol.
, vol.594
, pp. 5735-5748
-
-
Morrison, E.E.1
Bailey, M.A.2
Dear, J.W.3
-
97
-
-
84867575631
-
Comparison of protein, microRNA, and mRNA yields using different methods of urinary exosome isolation for the discovery of kidney disease biomarkers
-
Alvarez, M. L., Khosroheidari, M., Kanchi Ravi, R. & DiStefano, J. K. Comparison of protein, microRNA, and mRNA yields using different methods of urinary exosome isolation for the discovery of kidney disease biomarkers. Kidney Int. 82, 1024-1032 (2012).
-
(2012)
Kidney Int.
, vol.82
, pp. 1024-1032
-
-
Alvarez, M.L.1
Khosroheidari, M.2
Kanchi Ravi, R.3
DiStefano, J.K.4
-
98
-
-
84864537283
-
Microparticles and microRNAs of endothelial progenitor cells ameliorate acute kidney injury
-
Bitzer, M., Ben-Dov, I. Z. & Thum, T. Microparticles and microRNAs of endothelial progenitor cells ameliorate acute kidney injury. Kidney Int. 82, 375-377 (2012).
-
(2012)
Kidney Int.
, vol.82
, pp. 375-377
-
-
Bitzer, M.1
Ben-Dov, I.Z.2
Thum, T.3
-
99
-
-
79952461058
-
Nanodiamond therapeutic delivery agents mediate enhanced chemoresistant tumor treatment
-
Chow, E. K. et al. Nanodiamond therapeutic delivery agents mediate enhanced chemoresistant tumor treatment. Sci. Transl Med. 3, 73ra21 (2011).
-
(2011)
Sci. Transl Med.
, vol.3
, pp. 73ra21
-
-
Chow, E.K.1
-
100
-
-
84888384768
-
Adsorption of drugs on nanodiamond: Toward development of a drug delivery platform
-
Mochalin, V. N. et al. Adsorption of drugs on nanodiamond: toward development of a drug delivery platform. Mol. Pharm. 10, 3728-3735 (2013).
-
(2013)
Mol. Pharm.
, vol.10
, pp. 3728-3735
-
-
Mochalin, V.N.1
-
101
-
-
84928527918
-
Nanodiamond-based chemotherapy and imaging
-
Ho, D. Nanodiamond-based chemotherapy and imaging. Cancer Treat. Res. 166, 85-102 (2015).
-
(2015)
Cancer Treat. Res.
, vol.166
, pp. 85-102
-
-
Ho, D.1
-
102
-
-
84922388192
-
Furin-mediated sequential delivery of anticancer cytokine and small-molecule drug shuttled by graphene
-
Jiang, T. et al. Furin-mediated sequential delivery of anticancer cytokine and small-molecule drug shuttled by graphene. Adv. Mater. 27, 1021-1028 (2015).
-
(2015)
Adv. Mater.
, vol.27
, pp. 1021-1028
-
-
Jiang, T.1
-
103
-
-
50249123111
-
PEGylated nanographene oxide for delivery of water-insoluble cancer drugs
-
Liu, Z., Robinson, J. T., Sun, X. & Dai, H. PEGylated nanographene oxide for delivery of water-insoluble cancer drugs. J. Am. Chem. Soc. 130, 10876-10877 (2008).
-
(2008)
J. Am. Chem. Soc.
, vol.130
, pp. 10876-10877
-
-
Liu, Z.1
Robinson, J.T.2
Sun, X.3
Dai, H.4
-
104
-
-
84877680982
-
Synergistic cytotoxicity of irinotecan and cisplatin in dual-drug targeted polymeric nanoparticles
-
Valencia, P. M. et al. Synergistic cytotoxicity of irinotecan and cisplatin in dual-drug targeted polymeric nanoparticles. Nanomedicine (Lond.) 8, 687-698 (2013).
-
(2013)
Nanomedicine (Lond.)
, vol.8
, pp. 687-698
-
-
Valencia, P.M.1
-
105
-
-
84960271129
-
Synergistic nanomedicine by combined gene and photothermal therapy
-
Kim, J., Kim, J., Jeong, C. & Kim, W. J. Synergistic nanomedicine by combined gene and photothermal therapy. Adv. Drug Deliv. Rev. 98, 99-112 (2016).
-
(2016)
Adv. Drug Deliv. Rev.
, vol.98
, pp. 99-112
-
-
Kim, J.1
Kim, J.2
Jeong, C.3
Kim, W.J.4
-
106
-
-
84867627449
-
Nanotheranostics for personalized medicine
-
Mura, S. & Couvreur, P. Nanotheranostics for personalized medicine. Adv. Drug Deliv. Rev. 64, 1394-1416 (2012).
-
(2012)
Adv. Drug Deliv. Rev.
, vol.64
, pp. 1394-1416
-
-
Mura, S.1
Couvreur, P.2
-
107
-
-
78651352062
-
Novel multifunctional nanoparticle mediates siRNA tumour delivery, visualisation and therapeutic tumour reduction in vivo
-
Kenny, G. D. et al. Novel multifunctional nanoparticle mediates siRNA tumour delivery, visualisation and therapeutic tumour reduction in vivo. J. Control. Release 149, 111-116 (2011).
-
(2011)
J. Control. Release
, vol.149
, pp. 111-116
-
-
Kenny, G.D.1
-
108
-
-
84994477358
-
Emerging nanomedicine approaches fighting tumor metastasis: Animal models, metastasis-targeted drug delivery, phototherapy, and immunotherapy
-
Liang, C., Xu, L., Song, G. & Liu, Z. Emerging nanomedicine approaches fighting tumor metastasis: animal models, metastasis-targeted drug delivery, phototherapy, and immunotherapy. Chem. Soc. Rev. http://dx. doi. org/10. 1039/C6CS00458J (2016).
-
(2016)
Chem. Soc. Rev.
-
-
Liang, C.1
Xu, L.2
Song, G.3
Liu, Z.4
-
109
-
-
79958810593
-
Copper selenide nanocrystals for photothermal therapy
-
Hessel, C. M. et al. Copper selenide nanocrystals for photothermal therapy. Nano Lett. 11, 2560-2566 (2011).
-
(2011)
Nano Lett.
, vol.11
, pp. 2560-2566
-
-
Hessel, C.M.1
-
110
-
-
0020438772
-
Reversible dissociation of triiodothyronine-nuclear receptor complexes by mercurial and chaotropic reagents
-
Ferreira, M. M., Bismuth, J. & Torresani, J. Reversible dissociation of triiodothyronine-nuclear receptor complexes by mercurial and chaotropic reagents. Biochem. Biophys. Res. Commun. 105, 244-251 (1982).
-
(1982)
Biochem. Biophys. Res. Commun.
, vol.105
, pp. 244-251
-
-
Ferreira, M.M.1
Bismuth, J.2
Torresani, J.3
-
111
-
-
84920935888
-
Polymeric synthetic nanoparticles for the induction of antigen-specific immunological tolerance
-
Maldonado, R. A. et al. Polymeric synthetic nanoparticles for the induction of antigen-specific immunological tolerance. Proc. Natl Acad. Sci. USA 112, E156-E165 (2015).
-
(2015)
Proc. Natl Acad. Sci. USA
, vol.112
, pp. E156-E165
-
-
Maldonado, R.A.1
-
112
-
-
84899912149
-
Adjuvant-carrying synthetic vaccine particles augment the immune response to encapsulated antigen and exhibit strong local immune activation without inducing systemic cytokine release
-
Ilyinskii, P. O. et al. Adjuvant-carrying synthetic vaccine particles augment the immune response to encapsulated antigen and exhibit strong local immune activation without inducing systemic cytokine release. Vaccine 32, 2882-2895 (2014).
-
(2014)
Vaccine
, vol.32
, pp. 2882-2895
-
-
Ilyinskii, P.O.1
-
113
-
-
84865317394
-
Engineering approaches to immunotherapy
-
Swartz, M. A., Hirosue, S. & Hubbell, J. A. Engineering approaches to immunotherapy. Sci. Transl Med. 4, 148rv149 (2012).
-
(2012)
Sci. Transl Med.
, vol.4
, pp. 148rv149
-
-
Swartz, M.A.1
Hirosue, S.2
Hubbell, J.A.3
-
114
-
-
84880877024
-
Applications of nanotechnology for immunology
-
Smith, D. M., Simon, J. K. & Baker, J. R. Jr. Applications of nanotechnology for immunology. Nat. Rev. Immunol. 13, 592-605 (2013).
-
(2013)
Nat. Rev. Immunol.
, vol.13
, pp. 592-605
-
-
Smith, D.M.1
Simon, J.K.2
Baker, J.R.3
-
115
-
-
84886287251
-
Engineering synthetic vaccines using cues from natural immunity
-
Irvine, D. J., Swartz, M. A. & Szeto, G. L. Engineering synthetic vaccines using cues from natural immunity. Nat. Mater. 12, 978-990 (2013).
-
(2013)
Nat. Mater.
, vol.12
, pp. 978-990
-
-
Irvine, D.J.1
Swartz, M.A.2
Szeto, G.L.3
-
116
-
-
84889571890
-
Pathogen-like particles: Biomimetic vaccine carriers engineered at the nanoscale
-
Rosenthal, J. A., Chen, L., Baker, J. L., Putnam, D. & DeLisa, M. P. Pathogen-like particles: biomimetic vaccine carriers engineered at the nanoscale. Curr. Opin. Biotechnol. 28, 51-58 (2014).
-
(2014)
Curr. Opin. Biotechnol.
, vol.28
, pp. 51-58
-
-
Rosenthal, J.A.1
Chen, L.2
Baker, J.L.3
Putnam, D.4
DeLisa, M.P.5
-
117
-
-
84933564632
-
A mucosal vaccine against Chlamydia trachomatis generates two waves of protective memory
-
Stary, G. et al. A mucosal vaccine against Chlamydia trachomatis generates two waves of protective memory T. cells. Science 348, aaa8205 (2015).
-
(2015)
T. Cells. Science
, vol.348
, pp. aaa8205
-
-
Stary, G.1
-
118
-
-
12144287593
-
The targeting of anionized polyvinylpyrrolidone to the renal system
-
Kodaira, H. et al. The targeting of anionized polyvinylpyrrolidone to the renal system. Biomaterials 25, 4309-4315 (2004).
-
(2004)
Biomaterials
, vol.25
, pp. 4309-4315
-
-
Kodaira, H.1
-
119
-
-
56949085259
-
Tumor-targeted HPMA copolymer-(RGDfK)-(CHX-A''-DTPA) conjugates show increased kidney accumulation
-
Borgman, M. P. et al. Tumor-targeted HPMA copolymer-(RGDfK)-(CHX-A''-DTPA) conjugates show increased kidney accumulation. J. Control. Release 132, 193-199 (2008).
-
(2008)
J. Control. Release
, vol.132
, pp. 193-199
-
-
Borgman, M.P.1
-
120
-
-
84902083811
-
Kidney-specific drug delivery system for renal fibrosis based on coordination-driven assembly of catechol-derived chitosan
-
Qiao, H. et al. Kidney-specific drug delivery system for renal fibrosis based on coordination-driven assembly of catechol-derived chitosan. Biomaterials 35, 7157-7171 (2014).
-
(2014)
Biomaterials
, vol.35
, pp. 7157-7171
-
-
Qiao, H.1
-
121
-
-
62649127648
-
Specific renal uptake of randomly 50% N-acetylated low molecular weight chitosan
-
Yuan, Z. X. et al. Specific renal uptake of randomly 50% N-acetylated low molecular weight chitosan. Mol. Pharm. 6, 305-314 (2009).
-
(2009)
Mol. Pharm.
, vol.6
, pp. 305-314
-
-
Yuan, Z.X.1
-
122
-
-
78649448612
-
Drug targeting to the kidney: Advances in the active targeting of therapeutics to proximal tubular cells
-
Dolman, M. E., Harmsen, S., Storm, G., Hennink, W. E. & Kok, R. J. Drug targeting to the kidney: advances in the active targeting of therapeutics to proximal tubular cells. Adv. Drug Deliv. Rev. 62, 1344-1357 (2010).
-
(2010)
Adv. Drug Deliv. Rev.
, vol.62
, pp. 1344-1357
-
-
Dolman, M.E.1
Harmsen, S.2
Storm, G.3
Hennink, W.E.4
Kok, R.J.5
-
123
-
-
78649446025
-
Targeting podocyte-associated diseases
-
Leeuwis, J. W., Nguyen, T. Q., Dendooven, A., Kok, R. J. & Goldschmeding, R. Targeting podocyte-associated diseases. Adv. Drug Deliv. Rev. 62, 1325-1336 (2010).
-
(2010)
Adv. Drug Deliv. Rev.
, vol.62
, pp. 1325-1336
-
-
Leeuwis, J.W.1
Nguyen, T.Q.2
Dendooven, A.3
Kok, R.J.4
Goldschmeding, R.5
-
124
-
-
84855443297
-
Dendrimer-based macromolecular conjugate for the kidney-directed delivery of a multitargeted sunitinib analogue
-
Dolman, M. E. et al. Dendrimer-based macromolecular conjugate for the kidney-directed delivery of a multitargeted sunitinib analogue. Macromol. Biosci. 12, 93-103 (2012).
-
(2012)
Macromol. Biosci.
, vol.12
, pp. 93-103
-
-
Dolman, M.E.1
-
125
-
-
79960496422
-
Enhanced accumulation of low-molecular-weight chitosan in kidneys: A study on the influence of N-acetylation of chitosan on the renal targeting
-
Yuan, Z. X. et al. Enhanced accumulation of low-molecular-weight chitosan in kidneys: a study on the influence of N-acetylation of chitosan on the renal targeting. J. Drug Target. 19, 540-551 (2011).
-
(2011)
J. Drug Target.
, vol.19
, pp. 540-551
-
-
Yuan, Z.X.1
-
126
-
-
84906874032
-
Megalin-mediated specific uptake of chitosan/siRNA nanoparticles in mouse kidney proximal tubule epithelial cells enables AQP1 gene silencing
-
Gao, S. et al. Megalin-mediated specific uptake of chitosan/siRNA nanoparticles in mouse kidney proximal tubule epithelial cells enables AQP1 gene silencing. Theranostics 4, 1039-1051 (2014).
-
(2014)
Theranostics
, vol.4
, pp. 1039-1051
-
-
Gao, S.1
-
127
-
-
79955014321
-
Single application of low-dose mycophenolate mofetil-OX7-immunoliposomes ameliorates experimental mesangial proliferative glomerulonephritis
-
Suana, A. J. et al. Single application of low-dose mycophenolate mofetil-OX7-immunoliposomes ameliorates experimental mesangial proliferative glomerulonephritis. J. Pharmacol. Exp. Ther. 337, 411-422 (2011).
-
(2011)
J. Pharmacol. Exp. Ther.
, vol.337
, pp. 411-422
-
-
Suana, A.J.1
-
128
-
-
39449138103
-
Drug targeting using OX7-immunoliposomes: Correlation between Thy1. 1 antigen expression and tissue distribution in the rat
-
Tuffin, G., Huwyler, J., Waelti, E., Hammer, C. & Marti, H. P. Drug targeting using OX7-immunoliposomes: correlation between Thy1. 1 antigen expression and tissue distribution in the rat. J. Drug Target. 16, 156-166 (2008).
-
(2008)
J. Drug Target.
, vol.16
, pp. 156-166
-
-
Tuffin, G.1
Huwyler, J.2
Waelti, E.3
Hammer, C.4
Marti, H.P.5
-
129
-
-
34247647106
-
Advances in targeting drug delivery to glomerular mesangial cells by long circulating cationic liposomes for the treatment of glomerulonephritis
-
Morimoto, K. et al. Advances in targeting drug delivery to glomerular mesangial cells by long circulating cationic liposomes for the treatment of glomerulonephritis. Pharm. Res. 24, 946-954 (2007).
-
(2007)
Pharm. Res.
, vol.24
, pp. 946-954
-
-
Morimoto, K.1
-
130
-
-
33644873618
-
Immunoliposome targeting to mesangial cells: A promising strategy for specific drug delivery to the kidney
-
Tuffin, G., Waelti, E., Huwyler, J., Hammer, C. & Marti, H. P. Immunoliposome targeting to mesangial cells: a promising strategy for specific drug delivery to the kidney. J. Am. Soc. Nephrol. 16, 3295-3305 (2005).
-
(2005)
J. Am. Soc. Nephrol.
, vol.16
, pp. 3295-3305
-
-
Tuffin, G.1
Waelti, E.2
Huwyler, J.3
Hammer, C.4
Marti, H.P.5
-
131
-
-
57349198768
-
Anti-?8 integrin immunoliposomes in glomeruli of lupus-susceptible mice: A novel system for delivery of therapeutic agents to the renal glomerulus in systemic lupus erythematosus
-
Scindia, Y., Deshmukh, U., Thimmalapura, P. R. & Bagavant, H. Anti-?8 integrin immunoliposomes in glomeruli of lupus-susceptible mice: a novel system for delivery of therapeutic agents to the renal glomerulus in systemic lupus erythematosus. Arthritis Rheum. 58, 3884-3891 (2008).
-
(2008)
Arthritis Rheum.
, vol.58
, pp. 3884-3891
-
-
Scindia, Y.1
Deshmukh, U.2
Thimmalapura, P.R.3
Bagavant, H.4
-
132
-
-
84911945024
-
Biocompatibility, uptake and endocytosis pathways of polystyrene nanoparticles in primary human renal epithelial cells
-
Monti, D. M. et al. Biocompatibility, uptake and endocytosis pathways of polystyrene nanoparticles in primary human renal epithelial cells. J. Biotechnol. 193, 3-10 (2015).
-
(2015)
J. Biotechnol.
, vol.193
, pp. 3-10
-
-
Monti, D.M.1
-
133
-
-
84915784440
-
Gd-encapsulated carbonaceous dots with efficient renal clearance for magnetic resonance imaging
-
Chen, H. et al. Gd-encapsulated carbonaceous dots with efficient renal clearance for magnetic resonance imaging. Adv. Mater. 26, 6761-6766 (2014).
-
(2014)
Adv. Mater.
, vol.26
, pp. 6761-6766
-
-
Chen, H.1
-
134
-
-
84899624201
-
Passing through the renal clearance barrier: Toward ultrasmall sizes with stable ligands for potential clinical applications
-
Zhang, X. D. et al. Passing through the renal clearance barrier: toward ultrasmall sizes with stable ligands for potential clinical applications. Int. J. Nanomedicine 9, 2069-2072 (2014).
-
(2014)
Int. J. Nanomedicine
, vol.9
, pp. 2069-2072
-
-
Zhang, X.D.1
-
135
-
-
55949126429
-
Clearance properties of nano-sized particles and molecules as imaging agents: Considerations and caveats
-
Longmire, M., Choyke, P. L. & Kobayashi, H. Clearance properties of nano-sized particles and molecules as imaging agents: considerations and caveats. Nanomedicine (Lond.) 3, 703-717 (2008).
-
(2008)
Nanomedicine (Lond.)
, vol.3
, pp. 703-717
-
-
Longmire, M.1
Choyke, P.L.2
Kobayashi, H.3
-
136
-
-
84966431099
-
Ultrasmall inorganic nanoparticles: State-of-the-art and perspectives for biomedical applications
-
Zarschler, K. et al. Ultrasmall inorganic nanoparticles: state-of-the-art and perspectives for biomedical applications. Nanomedicine 12, 1663-1701 (2016).
-
(2016)
Nanomedicine
, vol.12
, pp. 1663-1701
-
-
Zarschler, K.1
-
137
-
-
84929069152
-
Characterizing the interactions of organic nanoparticles with renal epithelial cells in vivo
-
Nair, A. V., Keliher, E. J., Core, A. B., Brown, D. & Weissleder, R. Characterizing the interactions of organic nanoparticles with renal epithelial cells in vivo. ACS Nano 9, 3641-3653 (2015).
-
(2015)
ACS Nano
, vol.9
, pp. 3641-3653
-
-
Nair, A.V.1
Keliher, E.J.2
Core, A.B.3
Brown, D.4
Weissleder, R.5
-
138
-
-
84933500229
-
Renal interstitial fibrosis induced by high-dose mesoporous silica nanoparticles via the NF-?B signaling pathway
-
Chen, X. et al. Renal interstitial fibrosis induced by high-dose mesoporous silica nanoparticles via the NF-?B signaling pathway. Int. J. Nanomedicine 10, 1-22 (2015).
-
(2015)
Int. J. Nanomedicine
, vol.10
, pp. 1-22
-
-
Chen, X.1
-
139
-
-
58249141684
-
In vitro effects of nanoparticles on renal cells
-
L'Azou, B. et al. In vitro effects of nanoparticles on renal cells. Part. Fibre Toxicol. 5, 22 (2008).
-
(2008)
Part. Fibre Toxicol.
, vol.5
, pp. 22
-
-
L'Azou, B.1
-
140
-
-
33644964908
-
Acute toxicological effects of copper nanoparticles in vivo
-
Chen, Z. et al. Acute toxicological effects of copper nanoparticles in vivo. Toxicol. Lett. 163, 109-120 (2006).
-
(2006)
Toxicol. Lett.
, vol.163
, pp. 109-120
-
-
Chen, Z.1
-
141
-
-
0034824693
-
Effect of steroid-liposome on immunohistopathology of IgA nephropathy in ddY mice
-
Liao, J. et al. Effect of steroid-liposome on immunohistopathology of IgA nephropathy in ddY mice. Nephron 89, 194-200 (2001).
-
(2001)
Nephron
, vol.89
, pp. 194-200
-
-
Liao, J.1
-
142
-
-
4644290461
-
Liposome-mediated transfer of nitric oxide synthase gene improves renal function in ureteral obstruction in rats
-
Ito, K. et al. Liposome-mediated transfer of nitric oxide synthase gene improves renal function in ureteral obstruction in rats. Kidney Int. 66, 1365-1375 (2004).
-
(2004)
Kidney Int.
, vol.66
, pp. 1365-1375
-
-
Ito, K.1
-
143
-
-
84939644520
-
Polymeric nanoparticle drug delivery technologies for oral delivery applications
-
Pridgen, E. M., Alexis, F. & Farokhzad, O. C. Polymeric nanoparticle drug delivery technologies for oral delivery applications. Expert Opin. Drug Deliv. 12, 1459-1473 (2015).
-
(2015)
Expert Opin. Drug Deliv.
, vol.12
, pp. 1459-1473
-
-
Pridgen, E.M.1
Alexis, F.2
Farokhzad, O.C.3
-
144
-
-
84890028543
-
Transepithelial transport of Fc-targeted nanoparticles by the neonatal Fc receptor for oral delivery
-
Pridgen, E. M. et al. Transepithelial transport of Fc-targeted nanoparticles by the neonatal Fc receptor for oral delivery. Sci. Transl Med. 5, 213ra167 (2013).
-
(2013)
Sci. Transl Med.
, vol.5
, pp. 213ra167
-
-
Pridgen, E.M.1
-
145
-
-
84975718105
-
Mechanisms of transport of polymeric and lipidic nanoparticles across the intestinal barrier
-
Beloqui, A., des Rieux, A. & Preat, V. Mechanisms of transport of polymeric and lipidic nanoparticles across the intestinal barrier. Adv. Drug Deliv. Rev. http://dx. doi. org/10. 1016/j. addr. 2016. 04. 014 (2016).
-
(2016)
Adv. Drug Deliv. Rev.
-
-
Beloqui, A.1
Des Rieux, A.2
Preat, V.3
-
146
-
-
84908299353
-
Overcoming the challenges in administering biopharmaceuticals: Formulation and delivery strategies
-
Mitragotri, S., Burke, P. A. & Langer, R. Overcoming the challenges in administering biopharmaceuticals: formulation and delivery strategies. Nat. Rev. Drug Discov. 13, 655-672 (2014).
-
(2014)
Nat. Rev. Drug Discov.
, vol.13
, pp. 655-672
-
-
Mitragotri, S.1
Burke, P.A.2
Langer, R.3
-
147
-
-
84961287124
-
Polymeric nanoparticles amenable to simultaneous installation of exterior targeting and interior therapeutic proteins
-
Zhu, X. et al. Polymeric nanoparticles amenable to simultaneous installation of exterior targeting and interior therapeutic proteins. Angew. Chem. Int. Ed. 55, 3309-3312 (2016).
-
(2016)
Angew. Chem. Int. Ed.
, vol.55
, pp. 3309-3312
-
-
Zhu, X.1
-
148
-
-
84855573512
-
Theranostic nanoplatforms for simultaneous cancer imaging and therapy: Current approaches and future perspectives
-
Choi, K. Y., Liu, G., Lee, S. & Chen, X. Theranostic nanoplatforms for simultaneous cancer imaging and therapy: current approaches and future perspectives. Nanoscale 4, 330-342 (2012).
-
(2012)
Nanoscale
, vol.4
, pp. 330-342
-
-
Choi, K.Y.1
Liu, G.2
Lee, S.3
Chen, X.4
-
149
-
-
84869103855
-
Multifunctional nanoparticles: Cost versus benefit of adding targeting and imaging capabilities
-
Cheng, Z., Al Zaki, A., Hui, J. Z., Muzykantov, V. R. & Tsourkas, A. Multifunctional nanoparticles: cost versus benefit of adding targeting and imaging capabilities. Science 338, 903-910 (2012).
-
(2012)
Science
, vol.338
, pp. 903-910
-
-
Cheng, Z.1
Al Zaki, A.2
Hui, J.Z.3
Muzykantov, V.R.4
Tsourkas, A.5
-
150
-
-
34547399502
-
Detailed identification of plasma proteins adsorbed on copolymer nanoparticles
-
Cedervall, T. et al. Detailed identification of plasma proteins adsorbed on copolymer nanoparticles. Angew. Chem. Int. Ed. 46, 5754-5756 (2007).
-
(2007)
Angew. Chem. Int. Ed.
, vol.46
, pp. 5754-5756
-
-
Cedervall, T.1
-
151
-
-
70249136214
-
Protein-nanoparticle interactions: What does the cell see? Nat
-
Lynch, I., Salvati, A. & Dawson, K. A. Protein-nanoparticle interactions: what does the cell see? Nat. Nanotechnol. 4, 546-547 (2009).
-
(2009)
Nanotechnol.
, vol.4
, pp. 546-547
-
-
Lynch, I.1
Salvati, A.2
Dawson, K.A.3
-
152
-
-
33847789142
-
Understanding the nanoparticle-protein corona using methods to quantify exchange rates and affinities of proteins for nanoparticles
-
Cedervall, T. et al. Understanding the nanoparticle-protein corona using methods to quantify exchange rates and affinities of proteins for nanoparticles. Proc. Natl Acad. Sci. USA 104, 2050-2055 (2007).
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 2050-2055
-
-
Cedervall, T.1
-
153
-
-
55749091647
-
Nanoparticle size and surface properties determine the protein corona with possible implications for biological impacts
-
Lundqvist, M. et al. Nanoparticle size and surface properties determine the protein corona with possible implications for biological impacts. Proc. Natl Acad. Sci. USA 105, 14265-14270 (2008).
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 14265-14270
-
-
Lundqvist, M.1
-
154
-
-
84856436072
-
Nanoparticle size and surface chemistry determine serum protein adsorption and macrophage uptake
-
Walkey, C. D., Olsen, J. B., Guo, H., Emili, A. & Chan, W. C. Nanoparticle size and surface chemistry determine serum protein adsorption and macrophage uptake. J. Am. Chem. Soc. 134, 2139-2147 (2012).
-
(2012)
J. Am. Chem. Soc.
, vol.134
, pp. 2139-2147
-
-
Walkey, C.D.1
Olsen, J.B.2
Guo, H.3
Emili, A.4
Chan, W.C.5
-
155
-
-
84927927406
-
Protein corona of nanoparticles: Distinct proteins regulate the cellular uptake
-
Ritz, S. et al. Protein corona of nanoparticles: distinct proteins regulate the cellular uptake. Biomacromolecules 16, 1311-1321 (2015).
-
(2015)
Biomacromolecules
, vol.16
, pp. 1311-1321
-
-
Ritz, S.1
-
156
-
-
9644272479
-
Pre-coating with serum albumin reduces receptor-mediated hepatic disposition of polystyrene nanosphere: Implications for rational design of nanoparticles
-
Ogawara, K. et al. Pre-coating with serum albumin reduces receptor-mediated hepatic disposition of polystyrene nanosphere: implications for rational design of nanoparticles. J. Control. Release 100, 451-455 (2004).
-
(2004)
J. Control. Release
, vol.100
, pp. 451-455
-
-
Ogawara, K.1
-
157
-
-
80052785486
-
Protein-nanoparticle interactions: Opportunities and challenges
-
Mahmoudi, M. et al. Protein-nanoparticle interactions: opportunities and challenges. Chem. Rev. 111, 5610-5637 (2011).
-
(2011)
Chem. Rev.
, vol.111
, pp. 5610-5637
-
-
Mahmoudi, M.1
-
158
-
-
84873853768
-
Biomolecular coronas provide the biological identity of nanosized materials
-
Monopoli, M. P., Aberg, C., Salvati, A. & Dawson, K. A. Biomolecular coronas provide the biological identity of nanosized materials. Nat. Nanotechnol. 7, 779-786 (2012).
-
(2012)
Nat. Nanotechnol.
, vol.7
, pp. 779-786
-
-
Monopoli, M.P.1
Aberg, C.2
Salvati, A.3
Dawson, K.A.4
-
159
-
-
0141725521
-
Complement activation following first exposure to pegylated liposomal doxorubicin (Doxil): Possible role in hypersensitivity reactions
-
Chanan-Khan, A. et al. Complement activation following first exposure to pegylated liposomal doxorubicin (Doxil): possible role in hypersensitivity reactions. Ann. Oncol. 14, 1430-1437 (2003).
-
(2003)
Ann. Oncol.
, vol.14
, pp. 1430-1437
-
-
Chanan-Khan, A.1
-
160
-
-
84960201366
-
PEGylation as a strategy for improving nanoparticle-based drug and gene delivery
-
Suk, J. S., Xu, Q., Kim, N., Hanes, J. & Ensign, L. M. PEGylation as a strategy for improving nanoparticle-based drug and gene delivery. Adv. Drug Deliv. Rev. 99, 28-51 (2016).
-
(2016)
Adv. Drug Deliv. Rev.
, vol.99
, pp. 28-51
-
-
Suk, J.S.1
Xu, Q.2
Kim, N.3
Hanes, J.4
Ensign, L.M.5
-
161
-
-
84958078423
-
Protein adsorption is required for stealth effect of poly(ethylene glycol)-and poly(phosphoester)-coated nanocarriers
-
Schottler, S. et al. Protein adsorption is required for stealth effect of poly(ethylene glycol)-and poly(phosphoester)-coated nanocarriers. Nat. Nanotechnol. 11, 372-377 (2016).
-
(2016)
Nat. Nanotechnol.
, vol.11
, pp. 372-377
-
-
Schottler, S.1
-
162
-
-
84873564939
-
Transferrin-functionalized nanoparticles lose their targeting capabilities when a biomolecule corona adsorbs on the surface
-
Salvati, A. et al. Transferrin-functionalized nanoparticles lose their targeting capabilities when a biomolecule corona adsorbs on the surface. Nat. Nanotechnol. 8, 137-143 (2013).
-
(2013)
Nat. Nanotechnol.
, vol.8
, pp. 137-143
-
-
Salvati, A.1
-
163
-
-
84896519424
-
Lipopeptide nanoparticles for potent and selective siRNA delivery in rodents and nonhuman primates
-
Dong, Y. et al. Lipopeptide nanoparticles for potent and selective siRNA delivery in rodents and nonhuman primates. Proc. Natl Acad. Sci. USA 111, 3955-3960 (2014).
-
(2014)
Proc. Natl Acad. Sci. USA
, vol.111
, pp. 3955-3960
-
-
Dong, Y.1
-
164
-
-
84907147220
-
Ex situ evaluation of the composition of protein corona of intravenously injected superparamagnetic nanoparticles in rats
-
Sakulkhu, U. et al. Ex situ evaluation of the composition of protein corona of intravenously injected superparamagnetic nanoparticles in rats. Nanoscale 6, 11439-11450 (2014).
-
(2014)
Nanoscale
, vol.6
, pp. 11439-11450
-
-
Sakulkhu, U.1
-
165
-
-
84896928606
-
Protein corona fingerprinting predicts the cellular interaction of gold and silver nanoparticles
-
Walkey, C. D. et al. Protein corona fingerprinting predicts the cellular interaction of gold and silver nanoparticles. ACS Nano 8, 2439-2455 (2014).
-
(2014)
ACS Nano
, vol.8
, pp. 2439-2455
-
-
Walkey, C.D.1
-
166
-
-
84961926971
-
Exploring cellular interactions of liposomes using protein corona fingerprints and physicochemical properties
-
Bigdeli, A. et al. Exploring cellular interactions of liposomes using protein corona fingerprints and physicochemical properties. ACS Nano 10, 3723-3737 (2016).
-
(2016)
ACS Nano
, vol.10
, pp. 3723-3737
-
-
Bigdeli, A.1
-
167
-
-
79955609960
-
Targeting kidney mesangium by nanoparticles of defined size
-
Choi, C. H., Zuckerman, J. E., Webster, P. & Davis, M. E. Targeting kidney mesangium by nanoparticles of defined size. Proc. Natl Acad. Sci. USA 108, 6656-6661 (2011).
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 6656-6661
-
-
Choi, C.H.1
Zuckerman, J.E.2
Webster, P.3
Davis, M.E.4
-
168
-
-
84937800081
-
Anti-PEG immunity: Emergence, characteristics, and unaddressed questions
-
Yang, Q. & Lai, S. K. Anti-PEG immunity: emergence, characteristics, and unaddressed questions. Wiley Interdiscip. Rev. Nanomed. Nanobiotechnol. 7, 655-677 (2015).
-
(2015)
Wiley Interdiscip. Rev. Nanomed. Nanobiotechnol.
, vol.7
, pp. 655-677
-
-
Yang, Q.1
Lai, S.K.2
-
169
-
-
21744437424
-
Accelerated blood clearance of PEGylated liposomes following preceding liposome injection: Effects of lipid dose and PEG surface-density and chain length of the first-dose liposomes
-
Ishida, T. et al. Accelerated blood clearance of PEGylated liposomes following preceding liposome injection: effects of lipid dose and PEG surface-density and chain length of the first-dose liposomes. J. Control. Release 105, 305-317 (2005).
-
(2005)
J. Control. Release
, vol.105
, pp. 305-317
-
-
Ishida, T.1
-
170
-
-
79953720006
-
Anti-PEG IgM response against PEGylated liposomes in mice and rats
-
Ichihara, M. et al. Anti-PEG IgM response against PEGylated liposomes in mice and rats. Pharmaceutics 3, 1-11 (2010).
-
(2010)
Pharmaceutics
, vol.3
, pp. 1-11
-
-
Ichihara, M.1
-
171
-
-
0034054078
-
Accelerated blood clearance and altered biodistribution of repeated injections of sterically stabilized liposomes
-
Dams, E. T. et al. Accelerated blood clearance and altered biodistribution of repeated injections of sterically stabilized liposomes. J. Pharmacol. Exp. Ther. 292, 1071-1079 (2000).
-
(2000)
J. Pharmacol. Exp. Ther.
, vol.292
, pp. 1071-1079
-
-
Dams, E.T.1
-
172
-
-
84918536630
-
Preclinical activity of nanoliposomal irinotecan is governed by tumor deposition and intratumor prodrug conversion
-
Kalra, A. V. et al. Preclinical activity of nanoliposomal irinotecan is governed by tumor deposition and intratumor prodrug conversion. Cancer Res. 74, 7003-7013 (2014).
-
(2014)
Cancer Res.
, vol.74
, pp. 7003-7013
-
-
Kalra, A.V.1
-
173
-
-
33750549679
-
Novel SN-38-incorporating polymeric micelles, NK012, eradicate vascular endothelial growth factor-secreting bulky tumors
-
Koizumi, F. et al. Novel SN-38-incorporating polymeric micelles, NK012, eradicate vascular endothelial growth factor-secreting bulky tumors. Cancer Res. 66, 10048-10056 (2006).
-
(2006)
Cancer Res.
, vol.66
, pp. 10048-10056
-
-
Koizumi, F.1
-
174
-
-
56449127975
-
Antitumor effect of SN-38-releasing polymeric micelles, NK012, on spontaneous peritoneal metastases from orthotopic gastric cancer in mice compared with irinotecan
-
Nakajima, T. E. et al. Antitumor effect of SN-38-releasing polymeric micelles, NK012, on spontaneous peritoneal metastases from orthotopic gastric cancer in mice compared with irinotecan. Cancer Res. 68, 9318-9322 (2008).
-
(2008)
Cancer Res.
, vol.68
, pp. 9318-9322
-
-
Nakajima, T.E.1
-
175
-
-
20944450473
-
NK105, a paclitaxel-incorporating micellar nanoparticle formulation, can extend in vivo antitumour activity and reduce the neurotoxicity of paclitaxel
-
Hamaguchi, T. et al. NK105, a paclitaxel-incorporating micellar nanoparticle formulation, can extend in vivo antitumour activity and reduce the neurotoxicity of paclitaxel. Br. J. Cancer 92, 1240-1246 (2005).
-
(2005)
Br. J. Cancer
, vol.92
, pp. 1240-1246
-
-
Hamaguchi, T.1
-
176
-
-
0029798164
-
Relationship between pharmacokinetics of unchanged cisplatin and nephrotoxicity after intravenous infusions of cisplatin to cancer patients
-
Nagai, N. et al. Relationship between pharmacokinetics of unchanged cisplatin and nephrotoxicity after intravenous infusions of cisplatin to cancer patients. Cancer Chemother. Pharmacol. 39, 131-137 (1996).
-
(1996)
Cancer Chemother. Pharmacol.
, vol.39
, pp. 131-137
-
-
Nagai, N.1
-
177
-
-
77957267066
-
Pharmacokinetic evaluation of doxorubicin plasma levels in normal and overweight patients with breast cancer and simulation of dose adjustment by different indexes of body mass
-
Barpe, D. R., Rosa, D. D. & Froehlich, P. E. Pharmacokinetic evaluation of doxorubicin plasma levels in normal and overweight patients with breast cancer and simulation of dose adjustment by different indexes of body mass. Eur. J. Pharm. Sci. 41, 458-463 (2010).
-
(2010)
Eur. J. Pharm. Sci.
, vol.41
, pp. 458-463
-
-
Barpe, D.R.1
Rosa, D.D.2
Froehlich, P.E.3
-
178
-
-
79851509838
-
Glomerular number and size variability and risk for kidney disease
-
Puelles, V. G. et al. Glomerular number and size variability and risk for kidney disease. Curr. Opin. Nephrol. Hypertens. 20, 7-15 (2011).
-
(2011)
Curr. Opin. Nephrol. Hypertens.
, vol.20
, pp. 7-15
-
-
Puelles, V.G.1
-
180
-
-
84888875014
-
The role of the glomerular endothelium in albumin handling
-
Satchell, S. The role of the glomerular endothelium in albumin handling. Nat. Rev. Nephrol. 9, 717-725 (2013).
-
(2013)
Nat. Rev. Nephrol.
, vol.9
, pp. 717-725
-
-
Satchell, S.1
-
181
-
-
84859814741
-
The glomerular basement membrane
-
Miner, J. H. The glomerular basement membrane. Exp. Cell Res. 318, 973-978 (2012).
-
(2012)
Exp. Cell Res.
, vol.318
, pp. 973-978
-
-
Miner, J.H.1
-
182
-
-
84928784396
-
Podocytes: Recent biomolecular developments
-
Armelloni, S. et al. Podocytes: recent biomolecular developments. Biomol. Concepts 5, 319-330 (2014).
-
(2014)
Biomol. Concepts
, vol.5
, pp. 319-330
-
-
Armelloni, S.1
-
183
-
-
84859844692
-
Mesangial cell biology
-
Abboud, H. E. Mesangial cell biology. Exp. Cell Res. 318, 979-985 (2012).
-
(2012)
Exp. Cell Res.
, vol.318
, pp. 979-985
-
-
Abboud, H.E.1
-
184
-
-
84906537428
-
The emergence of the glomerular parietal epithelial cell
-
Shankland, S. J., Smeets, B., Pippin, J. W. & Moeller, M. J. The emergence of the glomerular parietal epithelial cell. Nat. Rev. Nephrol. 10, 158-173 (2014).
-
(2014)
Nat. Rev. Nephrol.
, vol.10
, pp. 158-173
-
-
Shankland, S.J.1
Smeets, B.2
Pippin, J.W.3
Moeller, M.J.4
-
185
-
-
84860629012
-
Molecular mechanisms of acid-base sensing by the kidney
-
Brown, D. & Wagner, C. A. Molecular mechanisms of acid-base sensing by the kidney. J. Am. Soc. Nephrol. 23, 774-780 (2012).
-
(2012)
J. Am. Soc. Nephrol.
, vol.23
, pp. 774-780
-
-
Brown, D.1
Wagner, C.A.2
-
186
-
-
0016753740
-
Permselectivity of the glomerular capillary wall: III. Restricted transport of polyanions
-
Chang, R. L., Deen, W. M., Robertson, C. R. & Brenner, B. M. Permselectivity of the glomerular capillary wall: III. Restricted transport of polyanions. Kidney Int. 8, 212-218 (1975).
-
(1975)
Kidney Int.
, vol.8
, pp. 212-218
-
-
Chang, R.L.1
Deen, W.M.2
Robertson, C.R.3
Brenner, B.M.4
-
187
-
-
84887105075
-
A new mechanism for albuminuria-induced podocyte injury
-
Mallipattu, S. K. & He, J. C. A new mechanism for albuminuria-induced podocyte injury. J. Am. Soc. Nephrol. 24, 1709-1711 (2013).
-
(2013)
J. Am. Soc. Nephrol.
, vol.24
, pp. 1709-1711
-
-
Mallipattu, S.K.1
He, J.C.2
-
188
-
-
73849140878
-
Design considerations for tumour-targeted nanoparticles
-
Choi, H. S. et al. Design considerations for tumour-targeted nanoparticles. Nat. Nanotechnol. 5, 42-47 (2010).
-
(2010)
Nat. Nanotechnol.
, vol.5
, pp. 42-47
-
-
Choi, H.S.1
-
189
-
-
35148864458
-
Renal clearance of quantum dots
-
Choi, H. S. et al. Renal clearance of quantum dots. Nat. Biotechnol. 25, 1165-1170 (2007).
-
(2007)
Nat. Biotechnol.
, vol.25
, pp. 1165-1170
-
-
Choi, H.S.1
-
190
-
-
84886399675
-
Targeting therapeutics to the glomerulus with nanoparticles
-
Zuckerman, J. E. & Davis, M. E. Targeting therapeutics to the glomerulus with nanoparticles. Adv. Chronic Kidney Dis. 20, 500-507 (2013).
-
(2013)
Adv. Chronic Kidney Dis.
, vol.20
, pp. 500-507
-
-
Zuckerman, J.E.1
Davis, M.E.2
-
191
-
-
84896504632
-
Shaping cancer nanomedicine: The effect of particle shape on the in vivo journey of nanoparticles
-
Toy, R., Peiris, P. M., Ghaghada, K. B. & Karathanasis, E. Shaping cancer nanomedicine: the effect of particle shape on the in vivo journey of nanoparticles. Nanomedicine (Lond.) 9, 121-134 (2014).
-
(2014)
Nanomedicine (Lond.)
, vol.9
, pp. 121-134
-
-
Toy, R.1
Peiris, P.M.2
Ghaghada, K.B.3
Karathanasis, E.4
-
192
-
-
22244460241
-
Direct fabrication and harvesting of monodisperse, shape-specific nanobiomaterials
-
Rolland, J. P. et al. Direct fabrication and harvesting of monodisperse, shape-specific nanobiomaterials. J. Am. Chem. Soc. 127, 10096-10100 (2005).
-
(2005)
J. Am. Chem. Soc.
, vol.127
, pp. 10096-10100
-
-
Rolland, J.P.1
-
193
-
-
84879412284
-
Future of the particle replication in nonwetting templates (PRINT) technology
-
Xu, J. et al. Future of the particle replication in nonwetting templates (PRINT) technology. Angew. Chem. Int. Ed. 52, 6580-6589 (2013).
-
(2013)
Angew. Chem. Int. Ed.
, vol.52
, pp. 6580-6589
-
-
Xu, J.1
-
194
-
-
84941066997
-
Principles of nanoparticle design for overcoming biological barriers to drug delivery
-
Blanco, E., Shen, H. & Ferrari, M. Principles of nanoparticle design for overcoming biological barriers to drug delivery. Nat. Biotechnol. 33, 941-951 (2015).
-
(2015)
Nat. Biotechnol.
, vol.33
, pp. 941-951
-
-
Blanco, E.1
Shen, H.2
Ferrari, M.3
-
196
-
-
54949137268
-
Magnetic iron oxide nanoworms for tumor targeting and imaging
-
Park, J. H. et al. Magnetic iron oxide nanoworms for tumor targeting and imaging. Adv. Mater. 20, 1630-1635 (2008).
-
(2008)
Adv. Mater.
, vol.20
, pp. 1630-1635
-
-
Park, J.H.1
-
197
-
-
81755187274
-
Fluorescent nanorods and nanospheres for real-time in vivo probing of nanoparticle shape-dependent tumor penetration
-
Chauhan, V. P. et al. Fluorescent nanorods and nanospheres for real-time in vivo probing of nanoparticle shape-dependent tumor penetration. Angew. Chem. Int. Ed. 50, 11417-11420 (2011).
-
(2011)
Angew. Chem. Int. Ed.
, vol.50
, pp. 11417-11420
-
-
Chauhan, V.P.1
-
198
-
-
52649118065
-
The effect of shape on the margination dynamics of non-neutrally buoyant particles in two-dimensional shear flows
-
Gentile, F. et al. The effect of shape on the margination dynamics of non-neutrally buoyant particles in two-dimensional shear flows. J. Biomech. 41, 2312-2318 (2008).
-
(2008)
J. Biomech.
, vol.41
, pp. 2312-2318
-
-
Gentile, F.1
-
199
-
-
77955459129
-
Paradoxical glomerular filtration of carbon nanotubes
-
Ruggiero, A. et al. Paradoxical glomerular filtration of carbon nanotubes. Proc. Natl Acad. Sci. USA 107, 12369-12374 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 12369-12374
-
-
Ruggiero, A.1
-
200
-
-
34547178393
-
Particle shape: A new design parameter for micro-and nanoscale drug delivery carriers
-
Champion, J. A., Katare, Y. K. & Mitragotri, S. Particle shape: a new design parameter for micro-and nanoscale drug delivery carriers. J. Control. Release 121, 3-9 (2007).
-
(2007)
J. Control. Release
, vol.121
, pp. 3-9
-
-
Champion, J.A.1
Katare, Y.K.2
Mitragotri, S.3
-
201
-
-
77955175216
-
Strategies in the design of nanoparticles for therapeutic applications
-
Petros, R. A. & DeSimone, J. M. Strategies in the design of nanoparticles for therapeutic applications. Nat. Rev. Drug Discov. 9, 615-627 (2010).
-
(2010)
Nat. Rev. Drug Discov.
, vol.9
, pp. 615-627
-
-
Petros, R.A.1
DeSimone, J.M.2
-
202
-
-
84961779115
-
Targeted fibrillar nanocarbon RNAi treatment of acute kidney injury
-
Alidori, S. et al. Targeted fibrillar nanocarbon RNAi treatment of acute kidney injury. Sci. Transl Med. 8, 331ra339 (2016).
-
(2016)
Sci. Transl Med.
, vol.8
, pp. 331ra339
-
-
Alidori, S.1
-
203
-
-
49749128832
-
Carbon-nanotube shape and individualization critical for renal excretion
-
Lacerda, L. et al. Carbon-nanotube shape and individualization critical for renal excretion. Small 4, 1130-1132 (2008).
-
(2008)
Small
, vol.4
, pp. 1130-1132
-
-
Lacerda, L.1
-
204
-
-
84949322229
-
Nanoparticle uptake: The phagocyte problem
-
Gustafson, H. H., Holt-Casper, D., Grainger, D. W. & Ghandehari, H. Nanoparticle uptake: the phagocyte problem. Nano Today 10, 487-510 (2015).
-
(2015)
Nano Today
, vol.10
, pp. 487-510
-
-
Gustafson, H.H.1
Holt-Casper, D.2
Grainger, D.W.3
Ghandehari, H.4
-
205
-
-
73949087550
-
Effect of surface properties on nanoparticle-cell interactions
-
Verma, A. & Stellacci, F. Effect of surface properties on nanoparticle-cell interactions. Small 6, 12-21 (2010).
-
(2010)
Small
, vol.6
, pp. 12-21
-
-
Verma, A.1
Stellacci, F.2
-
206
-
-
77249104877
-
Effects of particle size and surface charge on cellular uptake and biodistribution of polymeric nanoparticles
-
He, C., Hu, Y., Yin, L., Tang, C. & Yin, C. Effects of particle size and surface charge on cellular uptake and biodistribution of polymeric nanoparticles. Biomaterials 31, 3657-3666 (2010).
-
(2010)
Biomaterials
, vol.31
, pp. 3657-3666
-
-
He, C.1
Hu, Y.2
Yin, L.3
Tang, C.4
Yin, C.5
-
207
-
-
0035834269
-
Long-circulating poly(ethylene glycol)-poly(D, L-lactide) block copolymer micelles with modulated surface charge
-
Yamamoto, Y., Nagasaki, Y., Kato, Y., Sugiyama, Y. & Kataoka, K. Long-circulating poly(ethylene glycol)-poly(D, L-lactide) block copolymer micelles with modulated surface charge. J. Control. Release 77, 27-38 (2001).
-
(2001)
J. Control. Release
, vol.77
, pp. 27-38
-
-
Yamamoto, Y.1
Nagasaki, Y.2
Kato, Y.3
Sugiyama, Y.4
Kataoka, K.5
-
208
-
-
59349116903
-
Knocking down barriers: Advances in siRNA delivery
-
Whitehead, K. A., Langer, R. & Anderson, D. G. Knocking down barriers: advances in siRNA delivery. Nat. Rev. Drug Discov. 8, 129-138 (2009).
-
(2009)
Nat. Rev. Drug Discov.
, vol.8
, pp. 129-138
-
-
Whitehead, K.A.1
Langer, R.2
Anderson, D.G.3
-
209
-
-
67249128859
-
The first targeted delivery of siRNA in humans via a self-assembling, cyclodextrin polymer-based nanoparticle: From concept to clinic
-
Davis, M. E. The first targeted delivery of siRNA in humans via a self-assembling, cyclodextrin polymer-based nanoparticle: from concept to clinic. Mol. Pharm. 6, 659-668 (2009).
-
(2009)
Mol. Pharm.
, vol.6
, pp. 659-668
-
-
Davis, M.E.1
-
210
-
-
84934919959
-
Long-circulating siRNA nanoparticles for validating Prohibitin1-targeted non-small cell lung cancer treatment
-
Zhu, X. et al. Long-circulating siRNA nanoparticles for validating Prohibitin1-targeted non-small cell lung cancer treatment. Proc. Natl Acad. Sci. USA 112, 7779-7784 (2015).
-
(2015)
Proc. Natl Acad. Sci. USA
, vol.112
, pp. 7779-7784
-
-
Zhu, X.1
-
211
-
-
84896699451
-
Cancer nanotechnology: The impact of passive and active targeting in the era of modern cancer biology
-
Bertrand, N., Wu, J., Xu, X., Kamaly, N. & Farokhzad, O. C. Cancer nanotechnology: the impact of passive and active targeting in the era of modern cancer biology. Adv. Drug Deliv. Rev. 66, 2-25 (2014).
-
(2014)
Adv. Drug Deliv. Rev.
, vol.66
, pp. 2-25
-
-
Bertrand, N.1
Wu, J.2
Xu, X.3
Kamaly, N.4
Farokhzad, O.C.5
-
212
-
-
84989937083
-
Short-and long-term tracking of anionic ultrasmall nanoparticles in kidney
-
Liang, X. et al. Short-and long-term tracking of anionic ultrasmall nanoparticles in kidney. ACS Nano 10, 387-395 (2016).
-
(2016)
ACS Nano
, vol.10
, pp. 387-395
-
-
Liang, X.1
-
213
-
-
66049109286
-
Glomerular endothelial cell fenestrations: An integral component of the glomerular filtration barrier
-
Satchell, S. C. & Braet, F. Glomerular endothelial cell fenestrations: an integral component of the glomerular filtration barrier. Am. J. Physiol. Renal Physiol. 296, F947-F956 (2009).
-
(2009)
Am. J. Physiol. Renal Physiol.
, vol.296
, pp. F947-F956
-
-
Satchell, S.C.1
Braet, F.2
-
214
-
-
84862121988
-
Endothelial glycocalyx: Permeability barrier and mechanosensor
-
Curry, F. E. & Adamson, R. H. Endothelial glycocalyx: permeability barrier and mechanosensor. Ann. Biomed. Eng. 40, 828-839 (2012).
-
(2012)
Ann. Biomed. Eng.
, vol.40
, pp. 828-839
-
-
Curry, F.E.1
Adamson, R.H.2
-
215
-
-
0034799334
-
Structural determinants of glomerular permeability
-
Deen, W. M., Lazzara, M. J. & Myers, B. D. Structural determinants of glomerular permeability. Am. J. Physiol. Renal Physiol. 281, F579-F596 (2001).
-
(2001)
Am. J. Physiol. Renal Physiol.
, vol.281
, pp. F579-F596
-
-
Deen, W.M.1
Lazzara, M.J.2
Myers, B.D.3
-
216
-
-
84944442033
-
Targeting the podocyte to treat glomerular kidney disease
-
Lal, M. A., Young, K. W. & Andag, U. Targeting the podocyte to treat glomerular kidney disease. Drug Discov. Today 20, 1228-1234 (2015).
-
(2015)
Drug Discov. Today
, vol.20
, pp. 1228-1234
-
-
Lal, M.A.1
Young, K.W.2
Andag, U.3
-
217
-
-
84903618995
-
Diagnostic performance of random urine samples using albumin concentration versus ratio of albumin to creatinine for microalbuminuria v screening in patients with diabetes mellitus: A systematic review and meta-analysis
-
Wu, H. Y. et al. Diagnostic performance of random urine samples using albumin concentration versus ratio of albumin to creatinine for microalbuminuria v screening in patients with diabetes mellitus: a systematic review and meta-analysis. JAMA Intern. Med. 174, 1108-1115 (2014).
-
(2014)
JAMA Intern. Med.
, vol.174
, pp. 1108-1115
-
-
Wu, H.Y.1
-
218
-
-
84905718745
-
In vivo endothelial siRNA delivery using polymeric nanoparticles with low molecular weight
-
Dahlman, J. E. et al. In vivo endothelial siRNA delivery using polymeric nanoparticles with low molecular weight. Nat. Nanotechnol. 9, 648-655 (2014).
-
(2014)
Nat. Nanotechnol.
, vol.9
, pp. 648-655
-
-
Dahlman, J.E.1
-
219
-
-
33644772211
-
Phase i study of liposome-encapsulated c-raf antisense oligodeoxyribonucleotide infusion in combination with radiation therapy in patients with advanced malignancies
-
Dritschilo, A. et al. Phase I study of liposome-encapsulated c-raf antisense oligodeoxyribonucleotide infusion in combination with radiation therapy in patients with advanced malignancies. Clin. Cancer Res. 12, 1251-1259 (2006).
-
(2006)
Clin. Cancer Res.
, vol.12
, pp. 1251-1259
-
-
Dritschilo, A.1
-
220
-
-
77449113087
-
Sustained delivery and efficacy of polymeric nanoparticles containing osteopontin and bone sialoprotein antisenses in rats with breast cancer bone metastasis
-
Elazar, V. et al. Sustained delivery and efficacy of polymeric nanoparticles containing osteopontin and bone sialoprotein antisenses in rats with breast cancer bone metastasis. Int. J. Cancer 126, 1749-1760 (2010).
-
(2010)
Int. J. Cancer
, vol.126
, pp. 1749-1760
-
-
Elazar, V.1
-
221
-
-
41149118880
-
Inhibition of proinflammatory genes in anti-GBM glomerulonephritis by targeted dexamethasone-loaded AbEsel liposomes
-
Asgeirsdottir, S. A. et al. Inhibition of proinflammatory genes in anti-GBM glomerulonephritis by targeted dexamethasone-loaded AbEsel liposomes. Am. J. Physiol. Renal Physiol. 294, F554-F561 (2008).
-
(2008)
Am. J. Physiol. Renal Physiol.
, vol.294
, pp. F554-F561
-
-
Asgeirsdottir, S.A.1
-
222
-
-
15644366697
-
Agrin is a major heparan sulfate proteoglycan in the human glomerular basement membrane
-
Groffen, A. J. et al. Agrin is a major heparan sulfate proteoglycan in the human glomerular basement membrane. J. Histochem. Cytochem. 46, 19-27 (1998).
-
(1998)
J. Histochem. Cytochem.
, vol.46
, pp. 19-27
-
-
Groffen, A.J.1
-
223
-
-
0027209657
-
Pores in the glomerular basement membrane revealed by ultrahigh-resolution scanning electron microscopy
-
Hironaka, K., Makino, H., Yamasaki, Y. & Ota, Z. Pores in the glomerular basement membrane revealed by ultrahigh-resolution scanning electron microscopy. Nephron 64, 647-649 (1993).
-
(1993)
Nephron
, vol.64
, pp. 647-649
-
-
Hironaka, K.1
Makino, H.2
Yamasaki, Y.3
Ota, Z.4
-
224
-
-
84885357905
-
Nanoscale protein architecture of the kidney glomerular basement membrane
-
Suleiman, H. et al. Nanoscale protein architecture of the kidney glomerular basement membrane. eLife 2, e01149 (2013).
-
(2013)
ELife
, vol.2
, pp. e01149
-
-
Suleiman, H.1
-
225
-
-
84877854206
-
Alport syndrome & thin basement membrane nephropathy
-
updated 25 Nov 2015
-
Kashtan, C. E. Alport syndrome & thin basement membrane nephropathy. GeneReviews https://www. ncbi. nlm. nih. gov/books/NBK1207/ (updated 25 Nov 2015).
-
GeneReviews
-
-
Kashtan, C.E.1
-
226
-
-
79958001586
-
A novel mutation of LAMB2 in a multigenerational mennonite family reveals a new phenotypic variant of Pierson syndrome
-
Mohney, B. G. et al. A novel mutation of LAMB2 in a multigenerational mennonite family reveals a new phenotypic variant of Pierson syndrome. Ophthalmology 118, 1137-1144 (2011).
-
(2011)
Ophthalmology
, vol.118
, pp. 1137-1144
-
-
Mohney, B.G.1
-
227
-
-
84876255289
-
Development and in vivo efficacy of targeted polymeric inflammation-resolving nanoparticles
-
Kamaly, N. et al. Development and in vivo efficacy of targeted polymeric inflammation-resolving nanoparticles. Proc. Natl Acad. Sci. USA 110, 6506-6511 (2013).
-
(2013)
Proc. Natl Acad. Sci. USA
, vol.110
, pp. 6506-6511
-
-
Kamaly, N.1
-
228
-
-
84857438167
-
Polycation-siRNA nanoparticles can disassemble at the kidney glomerular basement membrane
-
Zuckerman, J. E., Choi, C. H., Han, H. & Davis, M. E. Polycation-siRNA nanoparticles can disassemble at the kidney glomerular basement membrane. Proc. Natl Acad. Sci. USA 109, 3137-3142 (2012).
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, pp. 3137-3142
-
-
Zuckerman, J.E.1
Choi, C.H.2
Han, H.3
Davis, M.E.4
-
229
-
-
0032730875
-
Unraveling the mechanisms of glomerular ultrafiltration: Nephrin, a key component of the slit diaphragm
-
Tryggvason, K. Unraveling the mechanisms of glomerular ultrafiltration: nephrin, a key component of the slit diaphragm. J. Am. Soc. Nephrol. 10, 2440-2445 (1999).
-
(1999)
J. Am. Soc. Nephrol.
, vol.10
, pp. 2440-2445
-
-
Tryggvason, K.1
-
230
-
-
0028334836
-
Spatiotemporal expression of molecules associated with junctional complexes during the in vivo maturation of renal podocytes
-
Tassin, M. T., Beziau, A., Gubler, M. C. & Boyer, B. Spatiotemporal expression of molecules associated with junctional complexes during the in vivo maturation of renal podocytes. Int. J. Dev. Biol. 38, 45-54 (1994).
-
(1994)
Int. J. Dev. Biol.
, vol.38
, pp. 45-54
-
-
Tassin, M.T.1
Beziau, A.2
Gubler, M.C.3
Boyer, B.4
-
231
-
-
84984612004
-
The podocyte as a direct target for treatment of glomerular disease? Am
-
Mallipattu, S. K. & He, J. C. The podocyte as a direct target for treatment of glomerular disease? Am. J. Physiol. Renal Physiol. 311, F46-F51 (2016).
-
(2016)
J. Physiol. Renal Physiol.
, vol.311
, pp. F46-F51
-
-
Mallipattu, S.K.1
He, J.C.2
-
232
-
-
84947256703
-
Targeting rapamycin to podocytes using a vascular cell adhesion molecule-1 (VCAM-1)-harnessed SAINT-based lipid carrier system
-
Visweswaran, G. R. et al. Targeting rapamycin to podocytes using a vascular cell adhesion molecule-1 (VCAM-1)-harnessed SAINT-based lipid carrier system. PLoS ONE 10, e0138870 (2015).
-
(2015)
PLoS ONE
, vol.10
, pp. e0138870
-
-
Visweswaran, G.R.1
-
233
-
-
77955590203
-
Establishment of protein delivery systems targeting podocytes
-
Chiang, W. C. et al. Establishment of protein delivery systems targeting podocytes. PLoS ONE 5, e11837 (2010).
-
(2010)
PLoS ONE
, vol.5
, pp. e11837
-
-
Chiang, W.C.1
-
234
-
-
0037415556
-
The major histocompatibility complex-related Fc receptor for IgG (FcRn) binds albumin and prolongs its lifespan
-
Chaudhury, C. et al. The major histocompatibility complex-related Fc receptor for IgG (FcRn) binds albumin and prolongs its lifespan. J. Exp. Med. 197, 315-322 (2003).
-
(2003)
J. Exp. Med.
, vol.197
, pp. 315-322
-
-
Chaudhury, C.1
-
235
-
-
38049032013
-
Modification of kidney barrier function by the urokinase receptor
-
Wei, C. et al. Modification of kidney barrier function by the urokinase receptor. Nat. Med. 14, 55-63 (2008).
-
(2008)
Nat. Med.
, vol.14
, pp. 55-63
-
-
Wei, C.1
-
236
-
-
84911079823
-
Blocking ligand occupancy of the ?V?3 integrin inhibits the development of nephropathy in diabetic pigs
-
Maile, L. A. et al. Blocking ligand occupancy of the ?V?3 integrin inhibits the development of nephropathy in diabetic pigs. Endocrinology 155, 4665-4675 (2014).
-
(2014)
Endocrinology
, vol.155
, pp. 4665-4675
-
-
Maile, L.A.1
-
237
-
-
84911127140
-
Blocking ?V?3 integrin ligand occupancy inhibits the progression of albuminuria in diabetic rats
-
Maile, L. A. et al. Blocking ?V?3 integrin ligand occupancy inhibits the progression of albuminuria in diabetic rats. J. Diabetes Res. 2014, 421827 (2014).
-
(2014)
J. Diabetes Res.
, vol.2014
, pp. 421827
-
-
Maile, L.A.1
-
238
-
-
84868375553
-
Kidney podocytes as specific targets for cyclo(RGDfC)-modified nanoparticles
-
Pollinger, K. et al. Kidney podocytes as specific targets for cyclo(RGDfC)-modified nanoparticles. Small 8, 3368-3375 (2012).
-
(2012)
Small
, vol.8
, pp. 3368-3375
-
-
Pollinger, K.1
-
239
-
-
84961301013
-
SiRNA delivery to the glomerular mesangium using polycationic cyclodextrin nanoparticles containing siRNA
-
Zuckerman, J. E., Gale, A., Wu, P., Ma, R. & Davis, M. E. siRNA delivery to the glomerular mesangium using polycationic cyclodextrin nanoparticles containing siRNA. Nucleic Acid Ther. 25, 53-64 (2015).
-
(2015)
Nucleic Acid Ther.
, vol.25
, pp. 53-64
-
-
Zuckerman, J.E.1
Gale, A.2
Wu, P.3
Ma, R.4
Davis, M.E.5
-
240
-
-
84928350591
-
Designing drugs that combat kidney damage
-
Ramos, A. M. et al. Designing drugs that combat kidney damage. Expert Opin. Drug Discov. 10, 541-556 (2015).
-
(2015)
Expert Opin. Drug Discov.
, vol.10
, pp. 541-556
-
-
Ramos, A.M.1
-
241
-
-
84925678297
-
Diverse origins of the myofibroblast-implications for kidney fibrosis
-
Falke, L. L., Gholizadeh, S., Goldschmeding, R., Kok, R. J. & Nguyen, T. Q. Diverse origins of the myofibroblast-implications for kidney fibrosis. Nat. Rev. Nephrol. 11, 233-244 (2015).
-
(2015)
Nat. Rev. Nephrol.
, vol.11
, pp. 233-244
-
-
Falke, L.L.1
Gholizadeh, S.2
Goldschmeding, R.3
Kok, R.J.4
Nguyen, T.Q.5
-
242
-
-
84923273195
-
SiRNAs targeted to Smad4 prevent renal fibrosis in vivo
-
Morishita, Y. et al. siRNAs targeted to Smad4 prevent renal fibrosis in vivo. Sci. Rep. 4, 6424 (2014).
-
(2014)
Sci. Rep.
, vol.4
, pp. 6424
-
-
Morishita, Y.1
-
243
-
-
33845914939
-
Protection of renal ischemia injury using combination gene silencing of complement 3 and caspase 3 genes
-
Zheng, X. et al. Protection of renal ischemia injury using combination gene silencing of complement 3 and caspase 3 genes. Transplantation 82, 1781-1786 (2006).
-
(2006)
Transplantation
, vol.82
, pp. 1781-1786
-
-
Zheng, X.1
-
244
-
-
84927145660
-
Mesoscale nanoparticles selectively target the renal proximal tubule epithelium
-
Williams, R. M. et al. Mesoscale nanoparticles selectively target the renal proximal tubule epithelium. Nano Lett. 15, 2358-2364 (2015).
-
(2015)
Nano Lett.
, vol.15
, pp. 2358-2364
-
-
Williams, R.M.1
-
245
-
-
84856626648
-
Targeting of a platinum-bound sunitinib analog to renal proximal tubular cells
-
Dolman, M. E. et al. Targeting of a platinum-bound sunitinib analog to renal proximal tubular cells. Int. J. Nanomedicine 7, 417-433 (2012).
-
(2012)
Int. J. Nanomedicine
, vol.7
, pp. 417-433
-
-
Dolman, M.E.1
-
246
-
-
84929448714
-
Delivery of microRNA-146a with polyethylenimine nanoparticles inhibits renal fibrosis in vivo
-
Morishita, Y. et al. Delivery of microRNA-146a with polyethylenimine nanoparticles inhibits renal fibrosis in vivo. Int. J. Nanomedicine 10, 3475-3488 (2015).
-
(2015)
Int. J. Nanomedicine
, vol.10
, pp. 3475-3488
-
-
Morishita, Y.1
-
247
-
-
67650760958
-
Epidemiology of kidney cancer
-
Pascual, D. & Borque, A. Epidemiology of kidney cancer. Adv. Urol. 2008, 782381 (2008).
-
(2008)
Adv. Urol.
, vol.2008
, pp. 782381
-
-
Pascual, D.1
Borque, A.2
-
248
-
-
0034787791
-
Paclitaxel liposome aerosol treatment induces inhibition of pulmonary metastases in murine renal carcinoma model
-
Koshkina, N. V. et al. Paclitaxel liposome aerosol treatment induces inhibition of pulmonary metastases in murine renal carcinoma model. Clin. Cancer Res. 7, 3258-3262 (2001).
-
(2001)
Clin. Cancer Res.
, vol.7
, pp. 3258-3262
-
-
Koshkina, N.V.1
-
249
-
-
34547777296
-
Phase 1/2 clinical trial of interferon ?2b and weekly liposome-encapsulated all-trans retinoic acid in patients with advanced renal cell carcinoma
-
Boorjian, S. A. et al. Phase 1/2 clinical trial of interferon ?2b and weekly liposome-encapsulated all-trans retinoic acid in patients with advanced renal cell carcinoma. J. Immunother. 30, 655-662 (2007).
-
(2007)
J. Immunother.
, vol.30
, pp. 655-662
-
-
Boorjian, S.A.1
-
250
-
-
84973470608
-
Sustained inhibition of cMET-VEGFR2 signaling using liposome-mediated delivery increases efficacy and reduces toxicity in kidney cancer
-
Kulkarni, A. A., Vijaykumar, V. E., Natarajan, S. K., Sengupta, S. & Sabbisetti, V. S. Sustained inhibition of cMET-VEGFR2 signaling using liposome-mediated delivery increases efficacy and reduces toxicity in kidney cancer. Nanomedicine 12, 1853-1861 (2016).
-
(2016)
Nanomedicine
, vol.12
, pp. 1853-1861
-
-
Kulkarni, A.A.1
Vijaykumar, V.E.2
Natarajan, S.K.3
Sengupta, S.4
Sabbisetti, V.S.5
-
251
-
-
84922763495
-
Comparison of sorafenib-loaded poly (lactic/glycolic) acid and DPPC liposome nanoparticles in the in vitro treatment of renal cell carcinoma
-
Liu, J. et al. Comparison of sorafenib-loaded poly (lactic/glycolic) acid and DPPC liposome nanoparticles in the in vitro treatment of renal cell carcinoma. J. Pharm. Sci. 104, 1187-1196 (2015).
-
(2015)
J. Pharm. Sci.
, vol.104
, pp. 1187-1196
-
-
Liu, J.1
-
252
-
-
84860312346
-
Significant induction of apoptosis in renal cell carcinoma cells transfected with cationic multilamellar liposomes containing the human interferon-? Gene through activation of the intracellular type 1 interferon signal pathway
-
Takaha, N. et al. Significant induction of apoptosis in renal cell carcinoma cells transfected with cationic multilamellar liposomes containing the human interferon-? gene through activation of the intracellular type 1 interferon signal pathway. Int. J. Oncol. 40, 1441-1446 (2012).
-
(2012)
Int. J. Oncol.
, vol.40
, pp. 1441-1446
-
-
Takaha, N.1
-
253
-
-
77950543539
-
Inhibitory effects of cationic hybrid liposomes on the growth of human renal cell carcinoma
-
Umebayashi, M., Makizono, T., Ichihara, H., Matsumoto, Y. & Ueoka, R. Inhibitory effects of cationic hybrid liposomes on the growth of human renal cell carcinoma. Anticancer Res. 30, 327-337 (2010).
-
(2010)
Anticancer Res.
, vol.30
, pp. 327-337
-
-
Umebayashi, M.1
Makizono, T.2
Ichihara, H.3
Matsumoto, Y.4
Ueoka, R.5
-
254
-
-
51449104025
-
Inhibitory effects of three-component hybrid liposomes containing cationic lipids without drugs on the growth of human renal tumor cells in vitro
-
Umebayashi, M., Matsumoto, Y. & Ueoka, R. Inhibitory effects of three-component hybrid liposomes containing cationic lipids without drugs on the growth of human renal tumor cells in vitro. Biol. Pharm. Bull. 31, 1816-1817 (2008).
-
(2008)
Biol. Pharm. Bull.
, vol.31
, pp. 1816-1817
-
-
Umebayashi, M.1
Matsumoto, Y.2
Ueoka, R.3
-
255
-
-
54849186300
-
Significant antitumor activity of cationic multilamellar liposomes containing human interferon-? Gene in combination with 5-fluorouracil against human renal cell carcinoma
-
Yamamoto, K. et al. Significant antitumor activity of cationic multilamellar liposomes containing human interferon-? gene in combination with 5-fluorouracil against human renal cell carcinoma. Int. J. Oncol. 33, 565-571 (2008).
-
(2008)
Int. J. Oncol.
, vol.33
, pp. 565-571
-
-
Yamamoto, K.1
-
256
-
-
0037343243
-
Significant antitumoral activity of cationic multilamellar liposomes containing human IFN-? Gene against human renal cell carcinoma
-
Nakanishi, H. et al. Significant antitumoral activity of cationic multilamellar liposomes containing human IFN-? gene against human renal cell carcinoma. Clin. Cancer Res. 9, 1129-1135 (2003).
-
(2003)
Clin. Cancer Res.
, vol.9
, pp. 1129-1135
-
-
Nakanishi, H.1
-
257
-
-
0036207829
-
Phase II trial of pegylated-liposomal doxorubicin (Doxil) in renal cell cancer
-
Skubitz, K. M. Phase II trial of pegylated-liposomal doxorubicin (Doxil) in renal cell cancer. Invest. New Drugs 20, 101-104 (2002).
-
(2002)
Invest. New Drugs
, vol.20
, pp. 101-104
-
-
Skubitz, K.M.1
-
258
-
-
33646823935
-
In vitro enhanced cytotoxicity of tumor-infiltrating lymphocytes transfected with tumor necrosis factor-related apoptosis-inducing ligand and/or interleukin-2 gene in human renal cell carcinoma
-
Tian, J. Q. et al. In vitro enhanced cytotoxicity of tumor-infiltrating lymphocytes transfected with tumor necrosis factor-related apoptosis-inducing ligand and/or interleukin-2 gene in human renal cell carcinoma. Urology 67, 1093-1098 (2006).
-
(2006)
Urology
, vol.67
, pp. 1093-1098
-
-
Tian, J.Q.1
-
259
-
-
84920737412
-
A neutral lipid envelope-type nanoparticle composed of a pH-activated and Vitamin E-scaffold lipid-like material as a platform for a gene carrier targeting renal cell carcinoma
-
Akita, H. et al. A neutral lipid envelope-type nanoparticle composed of a pH-activated and vitamin E-scaffold lipid-like material as a platform for a gene carrier targeting renal cell carcinoma. J. Control. Release 200, 97-105 (2015).
-
(2015)
J. Control. Release
, vol.200
, pp. 97-105
-
-
Akita, H.1
-
260
-
-
71949098379
-
Tetraidothyroacetic acid (tetrac) and tetrac nanoparticles inhibit growth of human renal cell carcinoma xenografts
-
Yalcin, M. et al. Tetraidothyroacetic acid (tetrac) and tetrac nanoparticles inhibit growth of human renal cell carcinoma xenografts. Anticancer Res. 29, 3825-3831 (2009).
-
(2009)
Anticancer Res.
, vol.29
, pp. 3825-3831
-
-
Yalcin, M.1
-
261
-
-
84965084320
-
Immunotherapies in early and advanced renal cell cancer
-
Kasenda, B., Larkin, J. & Gore, M. Immunotherapies in early and advanced renal cell cancer. Prog. Tumor Res. 42, 1-10 (2015).
-
(2015)
Prog. Tumor Res.
, vol.42
, pp. 1-10
-
-
Kasenda, B.1
Larkin, J.2
Gore, M.3
-
262
-
-
0022858683
-
A new concept for macromolecular therapeutics in cancer chemotherapy: Mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs
-
Matsumura, Y. & Maeda, H. A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs. Cancer Res. 46, 6387-6392 (1986).
-
(1986)
Cancer Res
, vol.46
, pp. 6387-6392
-
-
Matsumura, Y.1
Maeda, H.2
-
263
-
-
0022495733
-
Microvascular permeability of normal and neoplastic tissues
-
Gerlowski, L. E. & Jain, R. K. Microvascular permeability of normal and neoplastic tissues. Microvasc. Res. 31, 288-305 (1986).
-
(1986)
Microvasc. Res.
, vol.31
, pp. 288-305
-
-
Gerlowski, L.E.1
Jain, R.K.2
-
264
-
-
84940956193
-
Toward a full understanding of the EPR effect in primary and metastatic tumors as well as issues related to its heterogeneity
-
Maeda, H. Toward a full understanding of the EPR effect in primary and metastatic tumors as well as issues related to its heterogeneity. Adv. Drug Deliv. Rev. 91, 3-6 (2015).
-
(2015)
Adv. Drug Deliv. Rev.
, vol.91
, pp. 3-6
-
-
Maeda, H.1
-
265
-
-
84947811317
-
Predicting therapeutic nanomedicine efficacy using a companion magnetic resonance imaging nanoparticle
-
Miller, M. A. et al. Predicting therapeutic nanomedicine efficacy using a companion magnetic resonance imaging nanoparticle. Sci. Transl Med. 7, 314ra183 (2015).
-
(2015)
Sci. Transl Med.
, vol.7
, pp. 314ra183
-
-
Miller, M.A.1
-
266
-
-
84993679147
-
Pilot study in patients with advanced solid tumors to evaluate feasibility of ferumoxytol (FMX) as tumor imaging agent prior to MM398, a nanoliposomal irinotecan (nalIRI) [abstract]
-
Ramanathan, R. K. et al. Pilot study in patients with advanced solid tumors to evaluate feasibility of ferumoxytol (FMX) as tumor imaging agent prior to MM398, a nanoliposomal irinotecan (nalIRI) [abstract]. Cancer Res. 74 (19 Suppl.), CT224 (2014).
-
(2014)
Cancer Res.
, vol.74
, Issue.19
, pp. CT224
-
-
Ramanathan, R.K.1
-
267
-
-
0032700799
-
Liposomal doxorubicin and conventionally fractionated radiotherapy in the treatment of locally advanced non-small-cell lung cancer and head and neck cancer
-
Koukourakis, M. I. et al. Liposomal doxorubicin and conventionally fractionated radiotherapy in the treatment of locally advanced non-small-cell lung cancer and head and neck cancer. J. Clin. Oncol. 17, 3512-3521 (1999).
-
(1999)
J. Clin. Oncol.
, vol.17
, pp. 3512-3521
-
-
Koukourakis, M.I.1
-
268
-
-
84903818206
-
High liposomal doxorubicin tumour tissue distribution, as determined by radiopharmaceutical labelling with 99mTc-LD, is associated with the response and survival of patients with unresectable pleural mesothelioma treated with a combination of liposomal doxorubicin and cisplatin
-
Arrieta, O. et al. High liposomal doxorubicin tumour tissue distribution, as determined by radiopharmaceutical labelling with 99mTc-LD, is associated with the response and survival of patients with unresectable pleural mesothelioma treated with a combination of liposomal doxorubicin and cisplatin. Cancer Chemother. Pharmacol. 74, 211-215 (2014).
-
(2014)
Cancer Chemother. Pharmacol.
, vol.74
, pp. 211-215
-
-
Arrieta, O.1
-
269
-
-
84963615026
-
Radiologic imaging of the renal parenchyma structure and function
-
Grenier, N., Merville, P. & Combe, C. Radiologic imaging of the renal parenchyma structure and function. Nat. Rev. Nephrol. 12, 348-359 (2016).
-
(2016)
Nat. Rev. Nephrol.
, vol.12
, pp. 348-359
-
-
Grenier, N.1
Merville, P.2
Combe, C.3
-
270
-
-
84905754409
-
Microfluidic organs-on-chips
-
Bhatia, S. N. & Ingber, D. E. Microfluidic organs-on-chips. Nat. Biotechnol. 32, 760-772 (2014).
-
(2014)
Nat. Biotechnol.
, vol.32
, pp. 760-772
-
-
Bhatia, S.N.1
Ingber, D.E.2
-
271
-
-
84960177173
-
Kidney-on-a-chip technology for drug-induced nephrotoxicity screening
-
Wilmer, M. J. et al. Kidney-on-a-chip technology for drug-induced nephrotoxicity screening. Trends Biotechnol. 34, 156-170 (2016).
-
(2016)
Trends Biotechnol.
, vol.34
, pp. 156-170
-
-
Wilmer, M.J.1
-
272
-
-
84882590738
-
Human kidney proximal tubule-on-a-chip for drug transport and nephrotoxicity assessment
-
Jang, K. J. et al. Human kidney proximal tubule-on-a-chip for drug transport and nephrotoxicity assessment. Integr. Biol. (Camb.) 5, 1119-1129 (2013).
-
(2013)
Integr. Biol. (Camb.)
, vol.5
, pp. 1119-1129
-
-
Jang, K.J.1
-
273
-
-
77951884924
-
A multi-layer microfluidic device for efficient culture and analysis of renal tubular cells
-
Jang, K. J. & Suh, K. Y. A multi-layer microfluidic device for efficient culture and analysis of renal tubular cells. Lab Chip 10, 36-42 (2010).
-
(2010)
Lab Chip
, vol.10
, pp. 36-42
-
-
Jang, K.J.1
Suh, K.Y.2
-
274
-
-
84859635020
-
Analysis of transcriptomic and proteomic profiles demonstrates improved Madin-Darby canine kidney cell function in a renal microfluidic biochip
-
Snouber, L. C. et al. Analysis of transcriptomic and proteomic profiles demonstrates improved Madin-Darby canine kidney cell function in a renal microfluidic biochip. Biotechnol. Prog. 28, 474-484 (2012).
-
(2012)
Biotechnol. Prog.
, vol.28
, pp. 474-484
-
-
Snouber, L.C.1
-
275
-
-
84890159896
-
Induction of epithelial-to-mesenchymal transition in proximal tubular epithelial cells on microfluidic devices
-
Zhou, M., Ma, H., Lin, H. & Qin, J. Induction of epithelial-to-mesenchymal transition in proximal tubular epithelial cells on microfluidic devices. Biomaterials 35, 1390-1401 (2014).
-
(2014)
Biomaterials
, vol.35
, pp. 1390-1401
-
-
Zhou, M.1
Ma, H.2
Lin, H.3
Qin, J.4
-
277
-
-
85017054630
-
A quantitative approach to screen for nephrotoxic compounds in vitro
-
Adler, M. et al. A quantitative approach to screen for nephrotoxic compounds in vitro. J. Am. Soc. Nephrol. 27, 1015-1028 (2016).
-
(2016)
J. Am. Soc. Nephrol.
, vol.27
, pp. 1015-1028
-
-
Adler, M.1
-
278
-
-
85003053593
-
Pharmacokinetic profile that reduces nephrotoxicity of gentamicin in a perfused kidney-on-a-chip
-
Kim, S. et al. Pharmacokinetic profile that reduces nephrotoxicity of gentamicin in a perfused kidney-on-a-chip. Biofabrication 8, 015021 (2016).
-
(2016)
Biofabrication
, vol.8
, pp. 015021
-
-
Kim, S.1
-
279
-
-
84875386413
-
Monitoring and robust induction of nephrogenic intermediate mesoderm from human pluripotent stem cells
-
Mae, S. et al. Monitoring and robust induction of nephrogenic intermediate mesoderm from human pluripotent stem cells. Nat. Commun. 4, 1367 (2013).
-
(2013)
Nat. Commun.
, vol.4
, pp. 1367
-
-
Mae, S.1
-
280
-
-
85016216170
-
How to grow a kidney: Patient-specific kidney organoids come of age
-
Schmidt-Ott, K. M. How to grow a kidney: patient-specific kidney organoids come of age. Nephrol. Dial. Transplant. http://dx. doi. org/10. 1093/ndt/gfw256 (2016).
-
(2016)
Nephrol. Dial. Transplant.
-
-
Schmidt-Ott, K.M.1
-
281
-
-
84992410754
-
3D culture supports long-term expansion of mouse and human nephrogenic progenitors
-
Li, Z. et al. 3D culture supports long-term expansion of mouse and human nephrogenic progenitors. Cell Stem Cell 19, 516-529 (2016).
-
(2016)
Cell Stem Cell
, vol.19
, pp. 516-529
-
-
Li, Z.1
-
282
-
-
84975275212
-
Modeling development and disease with organoids
-
Clevers, H. Modeling development and disease with organoids. Cell 165, 1586-1597 (2016).
-
(2016)
Cell
, vol.165
, pp. 1586-1597
-
-
Clevers, H.1
-
283
-
-
84997497874
-
A strategy for generating kidney organoids: Recapitulating the development in human pluripotent stem cells
-
Takasato, M. & Little, M. H. A strategy for generating kidney organoids: recapitulating the development in human pluripotent stem cells. Dev. Biol. http://dx. doi. org/10. 1016/j. ydbio. 2016. 08. 024 (2016).
-
(2016)
Dev. Biol.
-
-
Takasato, M.1
Little, M.H.2
-
284
-
-
84891298711
-
Directing human embryonic stem cell differentiation towards a renal lineage generates a self-organizing kidney
-
Takasato, M. et al. Directing human embryonic stem cell differentiation towards a renal lineage generates a self-organizing kidney. Nat. Cell Biol. 16, 118-126 (2014).
-
(2014)
Nat. Cell Biol.
, vol.16
, pp. 118-126
-
-
Takasato, M.1
-
285
-
-
0036468064
-
3D-biohybrid systems: Applications in drug screening
-
Reininger-Mack, A., Thielecke, H. & Robitzki, A. A. 3D-biohybrid systems: applications in drug screening. Trends Biotechnol. 20, 56-61 (2002).
-
(2002)
Trends Biotechnol
, vol.20
, pp. 56-61
-
-
Reininger-Mack, A.1
Thielecke, H.2
Robitzki, A.A.3
-
286
-
-
84901422704
-
Nanoparticle toxicity assessment using an in vitro 3D kidney organoid culture model
-
Astashkina, A. I. et al. Nanoparticle toxicity assessment using an in vitro 3D kidney organoid culture model. Biomaterials 35, 6323-6331 (2014).
-
(2014)
Biomaterials
, vol.35
, pp. 6323-6331
-
-
Astashkina, A.I.1
-
287
-
-
84859812143
-
3D organoid kidney culture model engineered for high-throughput nephrotoxicity assays
-
Astashkina, A. I., Mann, B. K., Prestwich, G. D. & Grainger, D. W. A. 3D organoid kidney culture model engineered for high-throughput nephrotoxicity assays. Biomaterials 33, 4700-4711 (2012).
-
(2012)
Biomaterials
, vol.33
, pp. 4700-4711
-
-
Astashkina, A.I.1
Mann, B.K.2
Prestwich, G.D.3
Grainger, D.W.A.4
-
288
-
-
84891362991
-
Microfluidic platform for combinatorial synthesis and optimization of targeted nanoparticles for cancer therapy
-
Valencia, P. M. et al. Microfluidic platform for combinatorial synthesis and optimization of targeted nanoparticles for cancer therapy. ACS Nano 7, 10671-10680 (2013).
-
(2013)
ACS Nano
, vol.7
, pp. 10671-10680
-
-
Valencia, P.M.1
-
289
-
-
84973311550
-
Targeted interleukin-10 nanotherapeutics developed with a microfluidic chip enhance resolution of inflammation in advanced atherosclerosis
-
Kamaly, N. et al. Targeted interleukin-10 nanotherapeutics developed with a microfluidic chip enhance resolution of inflammation in advanced atherosclerosis. ACS Nano 10, 5280-5292 (2016).
-
(2016)
ACS Nano
, vol.10
, pp. 5280-5292
-
-
Kamaly, N.1
-
290
-
-
54549109219
-
Microfluidic platform for controlled synthesis of polymeric nanoparticles
-
Karnik, R. et al. Microfluidic platform for controlled synthesis of polymeric nanoparticles. Nano Lett. 8, 2906-2912 (2008).
-
(2008)
Nano Lett.
, vol.8
, pp. 2906-2912
-
-
Karnik, R.1
-
291
-
-
77950152455
-
Single-step assembly of homogenous lipid-polymeric and lipid-quantum dot nanoparticles enabled by microfluidic rapid mixing
-
Valencia, P. M. et al. Single-step assembly of homogenous lipid-polymeric and lipid-quantum dot nanoparticles enabled by microfluidic rapid mixing. ACS Nano 4, 1671-1679 (2010).
-
(2010)
ACS Nano
, vol.4
, pp. 1671-1679
-
-
Valencia, P.M.1
-
292
-
-
79953058675
-
Synthesis of size-tunable polymeric nanoparticles enabled by 3D hydrodynamic flow focusing in single-layer microchannels
-
Rhee, M. et al. Synthesis of size-tunable polymeric nanoparticles enabled by 3D hydrodynamic flow focusing in single-layer microchannels. Adv. Mater. 23, H79-H83 (2011).
-
(2011)
Adv. Mater.
, vol.23
, pp. H79-H83
-
-
Rhee, M.1
-
293
-
-
84860344186
-
Rapid discovery of potent siRNA-containing lipid nanoparticles enabled by controlled microfluidic formulation
-
Chen, D. et al. Rapid discovery of potent siRNA-containing lipid nanoparticles enabled by controlled microfluidic formulation. J. Am. Chem. Soc. 134, 6948-6951 (2012).
-
(2012)
J. Am. Chem. Soc.
, vol.134
, pp. 6948-6951
-
-
Chen, D.1
-
294
-
-
84863854232
-
Mass production and size control of lipid-polymer hybrid nanoparticles through controlled microvortices
-
Kim, Y. et al. Mass production and size control of lipid-polymer hybrid nanoparticles through controlled microvortices. Nano Lett. 12, 3587-3591 (2012).
-
(2012)
Nano Lett.
, vol.12
, pp. 3587-3591
-
-
Kim, Y.1
-
295
-
-
84903478448
-
Ultra-high throughput synthesis of nanoparticles with homogeneous size distribution using a coaxial turbulent jet mixer
-
Lim, J. M. et al. Ultra-high throughput synthesis of nanoparticles with homogeneous size distribution using a coaxial turbulent jet mixer. ACS Nano 8, 6056-6065 (2014).
-
(2014)
ACS Nano
, vol.8
, pp. 6056-6065
-
-
Lim, J.M.1
-
296
-
-
84905670761
-
Correlating animal and human phase Ia/Ib clinical data with CALAA-01 a targeted, polymer-based nanoparticle containing siRNA
-
Zuckerman, J. E. et al. Correlating animal and human phase Ia/Ib clinical data with CALAA-01, a targeted, polymer-based nanoparticle containing siRNA. Proc. Natl Acad. Sci. USA 111, 11449-11454 (2014).
-
(2014)
Proc. Natl Acad. Sci. USA
, vol.111
, pp. 11449-11454
-
-
Zuckerman, J.E.1
-
297
-
-
84883789058
-
Correlating preclinical animal studies and human clinical trials of a multifunctional, polymeric nanoparticle
-
Eliasof, S. et al. Correlating preclinical animal studies and human clinical trials of a multifunctional, polymeric nanoparticle. Proc. Natl Acad. Sci. USA 110, 15127-15132 (2013).
-
(2013)
Proc. Natl Acad. Sci. USA
, vol.110
, pp. 15127-15132
-
-
Eliasof, S.1
-
298
-
-
84959243220
-
Kidney cell-specific knockdown: Anything but simple
-
Kohan, D. E. Kidney cell-specific knockdown: anything but simple. Am. J. Physiol. Renal Physiol. 309, F1007-F1008 (2015).
-
(2015)
Am. J. Physiol. Renal Physiol.
, vol.309
, pp. F1007-F1008
-
-
Kohan, D.E.1
-
299
-
-
84958238052
-
Bridging translation by improving preclinical study design in AKI
-
de Caestecker, M. et al. Bridging translation by improving preclinical study design in AKI. J. Am. Soc. Nephrol. 26, 2905-2916 (2015).
-
(2015)
J. Am. Soc. Nephrol.
, vol.26
, pp. 2905-2916
-
-
De Caestecker, M.1
-
300
-
-
84995503271
-
-
US National Library of Medicine. ClinicalTrials. gov
-
US National Library of Medicine. ClinicalTrials. gov https://clinicaltrials. gov/ct2/show/NCT00617981?term (2014).
-
(2014)
-
-
-
301
-
-
18144372419
-
Vaccination of metastatic melanoma patients with autologous dendritic cell (DC) derived-exosomes: Results of the first phase i clinical trial
-
Escudier, B. et al. Vaccination of metastatic melanoma patients with autologous dendritic cell (DC) derived-exosomes: results of the first phase I clinical trial. J. Transl Med. 3, 10 (2005).
-
(2005)
J. Transl Med.
, vol.3
, pp. 10
-
-
Escudier, B.1
|