The major histocompatibility complex-related Fc receptor for IgG (FcRn) binds albumin and prolongs its lifespan

Journal of Experimental Medicine

Volumn 197, Issue 3, 2003, Pages 315-322

  Chaudhury, Chaity ^a   Mehnaz, Samina ^a   Robinson, John M ^a   Hayton, William L ^a   Pearl, Dennis K ^a   Roopenian, Derry C ^b   Anderson, Clark L ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b JACKSON LABORATORY   (United States)

Author keywords

Antibody; Half life; Metabolism; Pharmacokinetics; Transport

Indexed keywords

FC RECEPTOR; HUMAN SERUM ALBUMIN; IMMUNOGLOBULIN G;

ANIMAL CELL; AREA UNDER THE CURVE; ARTICLE; BINDING AFFINITY; CHO CELL; DOSE TIME EFFECT RELATION; ENZYME LINKED IMMUNOSORBENT ASSAY; HALF LIFE TIME; MAJOR HISTOCOMPATIBILITY COMPLEX; NONHUMAN; PH; PRIORITY JOURNAL;

ANIMALS; CATTLE; CHO CELLS; CRICETINAE; HALF-LIFE; HISTOCOMPATIBILITY ANTIGENS CLASS I; HYDROGEN-ION CONCENTRATION; IMMUNOGLOBULIN G; MAJOR HISTOCOMPATIBILITY COMPLEX; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PROTEIN BINDING; RATS; RECEPTORS, FC; RECOMBINANT PROTEINS; SERUM ALBUMIN, BOVINE;

EID: 0037415556     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20021829     Document Type: Article

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