Superior therapeutic efficacy of nab-paclitaxel over cremophor-based paclitaxel in locally advanced and metastatic models of human pancreatic cancer

British Journal of Cancer

Volumn 115, Issue 4, 2016, Pages 442-453

  Rajeshkumar, N V ^a,f   Yabuuchi, Shinichi ^a   Pai, Shweta G ^a   Tong, Zeen ^b   Hou, Shihe ^b   Bateman, Scott ^b   Pierce, Daniel W ^b   Heise, Carla ^b   Von Hoff, Daniel D ^c   Maitra, Anirban ^d   Hidalgo, Manuel ^e  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CELGENE CORPORATION   (United States)

^c TRANSLATIONAL GENOMICS RESEARCH INSTITUTE   (United States)

^d UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^e Structural Biology and Biocomputing Programme   (Spain)

^f INTREXON CORPORATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CREMOPHOR BASED PACLITAXEL; GEMCITABINE; PACLITAXEL; UNCLASSIFIED DRUG; 130-NM ALBUMIN-BOUND PACLITAXEL; ALBUMINOID; CREMOPHOR; DEOXYCYTIDINE; MACROGOL DERIVATIVE;

ADVANCED CANCER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER COMBINATION CHEMOTHERAPY; CARCINOMA CELL; CELL PROLIFERATION; CONTROLLED STUDY; DISEASE COURSE; DRUG BLOOD LEVEL; DRUG EFFICACY; HEALTH CARE QUALITY; HUMAN; MALE; METASTASIS; MONOTHERAPY; MOUSE; NONHUMAN; PANCREAS ADENOCARCINOMA; PRIMARY TUMOR; PRIORITY JOURNAL; SURVIVAL RATE; TUMOR VOLUME; ANALOGS AND DERIVATIVES; ANIMAL; CARCINOMA, PANCREATIC DUCTAL; DRUG SCREENING; KIDNEY NEOPLASMS; LIVER NEOPLASMS; LUNG NEOPLASMS; NEOVASCULARIZATION (PATHOLOGY); NUDE MOUSE; PANCREATIC NEOPLASMS; PATHOLOGY; SECONDARY; SPLENIC NEOPLASMS;

ALBUMINS; ANIMALS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CARCINOMA, PANCREATIC DUCTAL; CELL PROLIFERATION; DEOXYCYTIDINE; HUMANS; KIDNEY NEOPLASMS; LIVER NEOPLASMS; LUNG NEOPLASMS; MALE; MICE; MICE, NUDE; NEOPLASM METASTASIS; NEOVASCULARIZATION, PATHOLOGIC; PACLITAXEL; PANCREATIC NEOPLASMS; POLYETHYLENE GLYCOLS; SPLENIC NEOPLASMS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84979273487     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/bjc.2016.215     Document Type: Article

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