-
1
-
-
0345097633
-
The discovery of HIV as the cause of AIDS
-
Gallo RC, Montagnier L. The discovery of HIV as the cause of AIDS. N. Engl. J. Med. 349(24), 2283-2285 (2003).
-
(2003)
N. Engl. J. Med
, vol.349
, Issue.24
, pp. 2283-2285
-
-
Gallo, R.C.1
Montagnier, L.2
-
3
-
-
84949676842
-
-
Fast-track: ending the AIDS epidemic by 2030
-
Fast-track: ending the AIDS epidemic by 2030. Geneva: UNAIDS (2014).
-
(2014)
Geneva UNAIDS
-
-
-
5
-
-
84949676842
-
-
The gap report
-
The gap report. Geneva: UNAIDS. (2014).
-
(2014)
Geneva UNAIDS
-
-
-
6
-
-
77952488307
-
Emerging nanotechnology approaches for HIV/AIDS treatment and prevention
-
Mamo T, Moseman EA, Kolishetti N et al. Emerging nanotechnology approaches for HIV/AIDS treatment and prevention. Nanomedicine (Lond.) 5(2), 269-285 (2010).
-
(2011)
Nanomedicine (Lond.)
, vol.5
, Issue.2
, pp. 269-285
-
-
Mamo, T.1
Moseman, E.A.2
Kolishetti, N.3
-
7
-
-
0032771991
-
Longer-term immunologic effects and side effects of successful antiretroviral therapy
-
Schooley RT. Longer-term immunologic effects and side effects of successful antiretroviral therapy. Clin. Infect. Dis. 29(1), 12-18 (1999).
-
(1999)
Clin. Infect. Dis
, vol.29
, Issue.1
, pp. 12-18
-
-
Schooley, R.T.1
-
8
-
-
20944438569
-
Adverse effects of antiretroviral therapy for HIV infection: A review of selected topics
-
Nolan D, Reiss P, Mallal S. Adverse effects of antiretroviral therapy for HIV infection: a review of selected topics. Expert Opin. Drug Safety 4(2), 201-218 (2005).
-
(2005)
Expert Opin. Drug Safety
, vol.4
, Issue.2
, pp. 201-218
-
-
Nolan, D.1
Reiss, P.2
Mallal, S.3
-
9
-
-
84871416782
-
Nanomedicine applications towards the cure of HIV
-
Lisziewicz J, Toke ER. Nanomedicine applications towards the cure of HIV. Nanomedicine (Lond.) 9(1), 28-38 (2013).
-
(2013)
Nanomedicine (Lond.)
, vol.9
, Issue.1
, pp. 28-38
-
-
Lisziewicz, J.1
Toke, E.R.2
-
10
-
-
84893830170
-
Persistent HIV-1 replication is associated with lower antiretroviral drug concentrations in lymphatic tissues
-
Fletcher CV, Staskus K, Wietgrefe SW et al. Persistent HIV-1 replication is associated with lower antiretroviral drug concentrations in lymphatic tissues. Proc. Natl Acad. Sci. USA 111(6), 2307-2312 (2014).
-
(2014)
Proc. Natl Acad. Sci. USA
, vol.111
, Issue.6
, pp. 2307-2312
-
-
Fletcher, C.V.1
Staskus, K.2
Wietgrefe, S.W.3
-
11
-
-
84873452231
-
-
NCT02165202
-
ClinicalTrials Database: NCT02165202. https://clinicaltrials.gov/ct2/show/NCT02165202
-
ClinicalTrials Database
-
-
-
12
-
-
84873452231
-
-
NCT02076178
-
ClinicalTrials Database: NCT02076178. https://clinicaltrials.gov/ct2/show/NCT02076178
-
ClinicalTrials Database
-
-
-
13
-
-
84937149202
-
Nanoformulation of antiretroviral drugs enhances their penetration across the blood brain barrier in mice
-
Fiandra L, Colombo M, Mazzucchelli S et al. Nanoformulation of antiretroviral drugs enhances their penetration across the blood brain barrier in mice. Nanomedicine (Lond.) 11(6), 1387-1397 (2015).
-
(2015)
Nanomedicine (Lond.)
, vol.11
, Issue.6
, pp. 1387-1397
-
-
Fiandra, L.1
Colombo, M.2
Mazzucchelli, S.3
-
14
-
-
84891932867
-
Safety, tolerability, and immunogenicity of repeated doses of dermavir, a candidate therapeutic HIV vaccine, in HIVinfected patients receiving combination antiretroviral therapy: Results of the ACTG 5176 trial
-
Rodriguez B, Asmuth DM, Matining RM et al. Safety, tolerability, and immunogenicity of repeated doses of dermavir, a candidate therapeutic HIV vaccine, in HIVinfected patients receiving combination antiretroviral therapy: results of the ACTG 5176 trial. J. Acquir. Immune Defic. Syndr. 64(4), 351-359 (2013).
-
(2013)
J. Acquir. Immune Defic. Syndr
, vol.64
, Issue.4
, pp. 351-359
-
-
Rodriguez, B.1
Asmuth, D.M.2
Matining, R.M.3
-
15
-
-
33847116733
-
Poly (propyleneimine) dendrimer based nanocontainers for targeting of efavirenz to human monocytes/macrophages in vitro
-
Dutta T, Agashe HB, Garg M, Balakrishnan P, Kabra M, Jain NK. Poly (propyleneimine) dendrimer based nanocontainers for targeting of efavirenz to human monocytes/macrophages in vitro. J. Drug Target. 15(1), 89-98 (2007).
-
(2007)
J. Drug Target
, vol.15
, Issue.1
, pp. 89-98
-
-
Dutta, T.1
Agashe, H.B.2
Garg, M.3
Balakrishnan, P.4
Kabra, M.5
Jain, N.K.6
-
16
-
-
84860244308
-
Nanotechnology and the treatment of HIV infection
-
Parboosing R, Maguire GE, Govender P, Kruger HG. Nanotechnology and the treatment of HIV infection. Viruses 4(4), 488-520 (2012).
-
(2012)
Viruses
, vol.4
, Issue.4
, pp. 488-520
-
-
Parboosing, R.1
Maguire, G.E.2
Govender, P.3
Kruger, H.G.4
-
17
-
-
75949086100
-
Efavirenzloaded polymeric micelles for pediatric anti-HIV pharmacotherapy with significantly higher oral bioavailability [corrected]
-
Chiappetta DA, Hocht C, Taira C, Sosnik A. Efavirenzloaded polymeric micelles for pediatric anti-HIV pharmacotherapy with significantly higher oral bioavailability [corrected]. Nanomedicine (Lond.) 5(1), 11-23 (2010).
-
(2011)
Nanomedicine (Lond.)
, vol.5
, Issue.1
, pp. 11-23
-
-
Chiappetta, D.A.1
Hocht, C.2
Taira, C.3
Sosnik, A.4
-
18
-
-
77955270290
-
Enhanced transdermal delivery of an anti-HIV agent via ethanolic liposomes
-
Dubey V, Mishra D, Nahar M, Jain V, Jain NK. Enhanced transdermal delivery of an anti-HIV agent via ethanolic liposomes. Nanomedicine (Lond.) 6(4), 590-596 (2010).
-
(2011)
Nanomedicine (Lond.)
, vol.6
, Issue.4
, pp. 590-596
-
-
Dubey, V.1
Mishra, D.2
Nahar, M.3
Jain, V.4
Jain, N.K.5
-
19
-
-
77951498994
-
Nanosuspension technology and its applications in drug delivery
-
Arunkumar N, Deecaraman M, Rani C. Nanosuspension technology and its applications in drug delivery. Asian J. Pharm. 3(3), 168 (2009).
-
(2009)
Asian J. Pharm
, vol.3
, Issue.3
, pp. 168
-
-
Arunkumar, N.1
Deecaraman, M.2
Rani, C.3
-
20
-
-
84873452231
-
-
NCT02178800
-
ClinicalTrials Database: NCT02178800. https://clinicaltrials.gov/ct2/show/NCT02178800
-
ClinicalTrials Database
-
-
-
21
-
-
84886089649
-
Long-acting injectable antiretrovirals for HIV treatment and prevention
-
Spreen WR, Margolis DA, Pottage JC Jr. Long-acting injectable antiretrovirals for HIV treatment and prevention. Curr. Opin. HIV AIDS 8(6), 565-571 (2013).
-
(2013)
Curr. Opin. HIV AIDS
, vol.8
, Issue.6
, pp. 565-571
-
-
Spreen, W.R.1
Margolis, D.A.2
Pottage, J.C.3
-
22
-
-
67449119172
-
Development of a long-acting injectable formulation with nanoparticles of rilpivirine (TMC278) for HIV treatment
-
Baert L, vanT Klooster G, Dries W et al. Development of a long-acting injectable formulation with nanoparticles of rilpivirine (TMC278) for HIV treatment. Eur. J. Pharm. Biopharm. 72(3), 502-508 (2009).
-
(2009)
Eur. J. Pharm. Biopharm
, vol.72
, Issue.3
, pp. 502-508
-
-
Baert, L.1
VanT Klooster, G.2
Dries, W.3
-
23
-
-
85016237583
-
Clinical treatment options infectious diseases: Update on PrEP implementation, adherence, and advances in delivery
-
Doblecki-Lewis S, Cohen S, Liu A. Clinical treatment options infectious diseases: update on PrEP implementation, adherence, and advances in delivery. Curr. Treat. Options Infect. Dis. 7(2), 101-112 (2015).
-
(2015)
Curr. Treat. Options Infect. Dis
, vol.7
, Issue.2
, pp. 101-112
-
-
Doblecki-Lewis, S.1
Cohen, S.2
Liu, A.3
-
24
-
-
84860201353
-
TMC278 long acting - A parenteral nanosuspension formulation that provides sustained clinically relevant plasma concentrations in HIV-negative volunteers
-
Mexico City, Mexico 3-8 August
-
Verloes R, vant Klooster G, Baert L et al. TMC278 long acting -a parenteral nanosuspension formulation that provides sustained clinically relevant plasma concentrations in HIV-negative volunteers. 17th International AIDS Conference. Mexico City, Mexico, 3-8 August 2008.
-
(2008)
17th International AIDS Conference
-
-
Verloes, R.1
Vant Klooster, G.2
Baert, L.3
-
25
-
-
84867696503
-
Pharmacodynamic and antiretroviral activities of combination nanoformulated antiretrovirals in HIV-1-infected human peripheral blood lymphocyte-reconstituted mice
-
Roy U, Mcmillan J, Alnouti Y et al. Pharmacodynamic and antiretroviral activities of combination nanoformulated antiretrovirals in HIV-1-infected human peripheral blood lymphocyte-reconstituted mice. J. Infect. Dis. 206(10), 1577-1588 (2012).
-
(2012)
J. Infect. Dis
, vol.206
, Issue.10
, pp. 1577-1588
-
-
Roy, U.1
Mcmillan, J.2
Alnouti, Y.3
-
26
-
-
84879014036
-
Preclinical pharmacokinetics and tissue distribution of long-acting nanoformulated antiretroviral therapy
-
Gautam N, Roy U, Balkundi S et al. Preclinical pharmacokinetics and tissue distribution of long-acting nanoformulated antiretroviral therapy. Antimicrob. Agents Chemother. 57(7), 3110-3120 (2013).
-
(2013)
Antimicrob. Agents Chemother
, vol.57
, Issue.7
, pp. 3110-3120
-
-
Gautam, N.1
Roy, U.2
Balkundi, S.3
-
27
-
-
84887248504
-
Long-acting parenteral nanoformulated antiretroviral therapy: Interest and attitudes of HIV-infected patients
-
Williams J, Sayles HR, Meza JL et al. Long-acting parenteral nanoformulated antiretroviral therapy: interest and attitudes of HIV-infected patients. Nanomedicine (Lond.) 8(11), 1807-1813 (2013).
-
(2013)
Nanomedicine (Lond.)
, vol.8
, Issue.11
, pp. 1807-1813
-
-
Williams, J.1
Sayles, H.R.2
Meza, J.L.3
-
28
-
-
84930086174
-
Physiologically based pharmacokinetic modelling to inform development of intramuscular long-acting nanoformulations for HIV
-
Rajoli RK, Back DJ, Rannard S et al. Physiologically based pharmacokinetic modelling to inform development of intramuscular long-acting nanoformulations for HIV. Clin. Pharmacokinet. 54(6), 639-650 (2015).
-
(2015)
Clin. Pharmacokinet
, vol.54
, Issue.6
, pp. 639-650
-
-
Rajoli, R.K.1
Back, D.J.2
Rannard, S.3
-
29
-
-
84921885400
-
Once-daily, single-tablet regimens for the treatment of HIV-1 infection
-
Truong WR, Schafer JJ, Short WR. Once-daily, single-tablet regimens for the treatment of HIV-1 infection. PT 40(1), 44-55 (2015).
-
(2015)
PT
, vol.40
, Issue.1
, pp. 44-55
-
-
Truong, W.R.1
Schafer, J.J.2
Short, W.R.3
-
30
-
-
84873452231
-
-
NCT02120352
-
ClinicalTrials Database: NCT02120352. https://clinicaltrials.gov/ct2/show/NCT02120352
-
ClinicalTrials Database
-
-
-
31
-
-
84873452231
-
-
NCT01031589
-
ClinicalTrials Database: NCT01031589. https://clinicaltrials.gov/ct2/show/NCT01031589
-
ClinicalTrials Database
-
-
-
32
-
-
84873452231
-
-
NCT01593046
-
ClinicalTrials Database: NCT01593046. https://clinicaltrials.gov/ct2/show/NCT01593046
-
ClinicalTrials Database
-
-
-
33
-
-
84873452231
-
-
NCT01565850
-
ClinicalTrials Database: NCT01565850. https://clinicaltrials.gov/ct2/show/NCT01565850
-
ClinicalTrials Database
-
-
-
34
-
-
84949675706
-
-
48 week study of tenofovir alafenamide (TAF) vs. Tenofovir disoproxil fumarate (TDF), each in a singletablet regimen (STR) with elvitegravir, cobicistat, and emtricitabine [E/C/F/TAF vs. E/C/F/TDF] for initial HIV treatment. Abstract IV-1464d. Denver, CO, USA 10-13 September
-
Sax P, Brar I, Elion R et al. 48 week study of tenofovir alafenamide (TAF) vs. Tenofovir disoproxil fumarate (TDF), each in a singletablet regimen (STR) with elvitegravir, cobicistat, and emtricitabine [E/C/F/TAF vs. E/C/F/TDF] for initial HIV treatment. Abstract IV-1464d. Presented at: The 53rd Interscience Conference on Antimicrobial Agents and Chemotherapy. Denver, CO, USA, 10-13 September 2013.
-
(2013)
Presented at the 53rd Interscience Conference on Antimicrobial Agents and Chemotherapy
-
-
Sax, P.1
Brar, I.2
Elion, R.3
-
35
-
-
84949648461
-
Lack of tenofovir alafenamide (TAF) effect on primary osteoblasts in vitro at clinically relevant drug concentrations. Abstract H-664
-
Denver, CO, USA 10-13 September
-
Liu Y, Kitrinos K, Babusis D et al. Lack of tenofovir alafenamide (TAF) effect on primary osteoblasts in vitro at clinically relevant drug concentrations. Abstract H-664. Presented at: The 53rd Interscience Conference on Antimicrobial Agents and Chemotherapy. Denver, CO, USA, 10-13 September 2013.
-
(2013)
Presented at the 53rd Interscience Conference on Antimicrobial Agents and Chemotherapy
-
-
Liu, Y.1
Kitrinos, K.2
Babusis, D.3
-
36
-
-
84949651617
-
-
Atripla (efavirenz/emtricitabine/tenofovir disoproxil fumarate) package insert, Foster City, California, USA
-
Atripla (efavirenz/emtricitabine/tenofovir disoproxil fumarate) package insert. Bristol-Myers Squibb and Gilead Sciences, Foster City, California, USA (2013).
-
(2013)
Bristol-Myers Squibb and Gilead Sciences
-
-
-
37
-
-
84873873617
-
Elvitegravir/Cobicistat/Emtricitabine/Tenofovir disoproxil fumarate tablets
-
Cada DJ, Torres S, Levien TL, Baker DE. Elvitegravir/Cobicistat/Emtricitabine/Tenofovir disoproxil fumarate tablets. Hosp. Pharm. 48(1), 48-56 (2013).
-
(2013)
Hosp. Pharm
, vol.48
, Issue.1
, pp. 48-56
-
-
Cada, D.J.1
Torres, S.2
Levien, T.L.3
Baker, D.E.4
-
38
-
-
84977139614
-
Cobicistat: A novel pharmacoenhancer for co-formulation with HIV protease and integrase inhibitors
-
Nathan B, Bayley J, Waters L, Post FA. Cobicistat: a novel pharmacoenhancer for co-formulation with hiv protease and integrase inhibitors. Infect. Dis. Ther. 2(2), 111-122 (2013).
-
(2013)
Infect. Dis. Ther
, vol.2
, Issue.2
, pp. 111-122
-
-
Nathan, B.1
Bayley, J.2
Waters, L.3
Post, F.A.4
-
39
-
-
84883650186
-
Cost-effectiveness of the once-daily efavirenz/emtricitabine/tenofovir tablet compared with the once-daily elvitegravir/cobicistat/emtricitabine/tenofovir tablet as firstline antiretroviral therapy in HIV-infected adults in the US
-
Juday T, Correll T, Anene A, Broder MS, Ortendahl J, Bentley T. Cost-effectiveness of the once-daily efavirenz/emtricitabine/tenofovir tablet compared with the once-daily elvitegravir/cobicistat/emtricitabine/tenofovir tablet as firstline antiretroviral therapy in HIV-infected adults in the US. Clinicoecon. Outcomes Res. 5, 437-445 (2013).
-
(2013)
Clinicoecon. Outcomes Res
, vol.5
, pp. 437-445
-
-
Juday, T.1
Correll, T.2
Anene, A.3
Broder, M.S.4
Ortendahl, J.5
Bentley, T.6
-
40
-
-
84884554042
-
Association between daily antiretroviral pill burden and treatment adherence, hospitalisation risk, and other healthcare utilisation and costs in a US medicaid population with HIV
-
Epub ahead of print
-
Cohen CJ, Meyers JL, Davis KL. Association between daily antiretroviral pill burden and treatment adherence, hospitalisation risk, and other healthcare utilisation and costs in a US medicaid population with HIV. BMJ Open 3(8), doi:10.1136/bmjopen-2013-003028 (2013) (Epub ahead of print).
-
(2013)
BMJ Open
, vol.3
, pp. 8
-
-
Cohen, C.J.1
Meyers, J.L.2
Davis, K.L.3
-
41
-
-
84898486385
-
Nanoparticle-based drug delivery to improve the efficacy of antiretroviral therapy in the central nervous system
-
Gomes MJ, Neves J, Sarmento B. Nanoparticle-based drug delivery to improve the efficacy of antiretroviral therapy in the central nervous system. Int. J. Nanomedicine 9, 1757-1769 (2014).
-
(2014)
Int. J. Nanomedicine
, vol.9
, pp. 1757-1769
-
-
Gomes, M.J.1
Neves, J.2
Sarmento, B.3
-
42
-
-
0034932659
-
Neuropathology and neurodegeneration in human immunodeficiency virus infection. Pathogenesis of HIV-induced lesions of the brain, correlations with HIV-associated disorders and modifications according to treatments
-
Gray F, Adle-Biassette H, Chretien F, Lorin de la Grandmaison G, Force G, Keohane C. Neuropathology and neurodegeneration in human immunodeficiency virus infection. Pathogenesis of HIV-induced lesions of the brain, correlations with HIV-associated disorders and modifications according to treatments. Clin. Neuropathol. 20(4), 146-55 (2001).
-
(2001)
Clin. Neuropathol
, vol.20
, Issue.4
, pp. 146-155
-
-
Gray, F.1
Adle-Biassette, H.2
Chretien, F.3
De La Lorin, G.G.4
Force, G.5
Keohane, C.6
-
43
-
-
84896727205
-
Towards nanomedicines for neuroAIDS
-
Sagar V, Pilakka-Kanthikeel S, Pottathil R, Saxena SK, Nair M. Towards nanomedicines for neuroAIDS. Rev. Med. Virol. 24(2), 103-124 (2014).
-
(2014)
Rev. Med. Virol
, vol.24
, Issue.2
, pp. 103-124
-
-
Sagar, V.1
Pilakka-Kanthikeel, S.2
Pottathil, R.3
Saxena, S.K.4
Nair, M.5
-
44
-
-
76849095367
-
Nanotechnology-based systems for the treatment and prevention of HIV/AIDS
-
das Neves J, Amiji MM, Bahia MF, Sarmento B. Nanotechnology-based systems for the treatment and prevention of HIV/AIDS. Adv. Drug Deliv. Rev. 62(4-5), 458-477 (2010).
-
(2011)
Adv. Drug Deliv. Rev
, vol.62
, Issue.4-5
, pp. 458-477
-
-
Das Neves, J.1
Amiji, M.M.2
Bahia, M.F.3
Sarmento, B.4
-
45
-
-
84869498397
-
Long-acting nanoformulated antiretroviral therapy elicits potent antiretroviral and neuroprotective responses in HIV-1-infected humanized mice
-
Dash PK, Gendelman HE, Roy U et al. Long-acting nanoformulated antiretroviral therapy elicits potent antiretroviral and neuroprotective responses in HIV-1-infected humanized mice. AIDS 26(17), 2135-2144 (2012).
-
(2012)
AIDS
, vol.26
, Issue.17
, pp. 2135-2144
-
-
Dash, P.K.1
Gendelman, H.E.2
Roy, U.3
-
46
-
-
84924657543
-
Prolongedacting, multi-targeting gallium nanoparticles potently inhibit growth of both HIV and mycobacteria in coinfected human macrophages
-
Narayanasamy P, Switzer BL, Britigan BE. Prolongedacting, multi-targeting gallium nanoparticles potently inhibit growth of both HIV and mycobacteria in coinfected human macrophages. Sci. Rep. 5, 8824 (2015).
-
(2015)
Sci. Rep
, vol.5
, pp. 8824
-
-
Narayanasamy, P.1
Switzer, B.L.2
Britigan, B.E.3
-
47
-
-
84930948323
-
New approaches to HIV vaccine development
-
Haynes BF. New approaches to HIV vaccine development. Curr. Opin. Immunol. 35, 39-47 (2015).
-
(2015)
Curr. Opin. Immunol
, vol.35
, pp. 39-47
-
-
Haynes, B.F.1
-
49
-
-
23944434447
-
Dendrimers as drugs: Discovery and preclinical and clinical development of dendrimer-based microbicides for HIV and STI prevention
-
Mccarthy TD, Karellas P, Henderson SA et al. Dendrimers as drugs: discovery and preclinical and clinical development of dendrimer-based microbicides for HIV and STI prevention. Mol. Pharm. 2(4), 312-318 (2005).
-
(2005)
Mol. Pharm
, vol.2
, Issue.4
, pp. 312-318
-
-
Mccarthy, T.D.1
Karellas, P.2
Henderson, S.A.3
-
50
-
-
77957870262
-
Structure activity relationship of dendrimer microbicides with dual action antiviral activity
-
Tyssen D, Henderson SA, Johnson A et al. Structure activity relationship of dendrimer microbicides with dual action antiviral activity. PLoS ONE 5(8), e12309 (2010).
-
(2011)
PLoS ONE
, vol.5
, Issue.8
, pp. e12309
-
-
Tyssen, D.1
Henderson, S.A.2
Johnson, A.3
-
51
-
-
16444385352
-
SPL7013 gel as a topical microbicide for prevention of vaginal transmission of SHIV89.6P in macaques
-
Jiang YH, Emau P, Cairns JS et al. SPL7013 gel as a topical microbicide for prevention of vaginal transmission of SHIV89.6P in macaques. AIDS Res. Hum. Retroviruses 21(3), 207-213 (2005).
-
(2005)
AIDS Res. Hum. Retroviruses
, vol.21
, Issue.3
, pp. 207-213
-
-
Jiang, Y.H.1
Emau, P.2
Cairns, J.S.3
-
52
-
-
33646449167
-
Preclinical safety and efficacy assessments of dendrimer-based (SPL7013) microbicide gel formulations in a nonhuman primate model
-
Patton DL, Cosgrove Sweeney YT, Mccarthy TD, Hillier SL. Preclinical safety and efficacy assessments of dendrimer-based (SPL7013) microbicide gel formulations in a nonhuman primate model. Antimicrob. Agents Chemother. 50(5), 1696-1700 (2006).
-
(2006)
Antimicrob. Agents Chemother
, vol.50
, Issue.5
, pp. 1696-1700
-
-
Patton, D.L.1
Cosgrove Sweeney, Y.T.2
Mccarthy, T.D.3
Hillier, S.L.4
-
53
-
-
85027950233
-
Phase 1 randomized trial of the vaginal safety and acceptability of SPL7013 gel (VivaGel sexually active young women (MTN-004)
-
Mcgowan I, Gomez K, Bruder K et al. Phase 1 randomized trial of the vaginal safety and acceptability of SPL7013 gel (VivaGel) in sexually active young women (MTN-004). AIDS 25 8 1057-1064 2011).
-
(2011)
AIDS
, vol.25
, Issue.8
, pp. 1057-1064
-
-
Mcgowan, I.1
Gomez, K.2
Bruder, K.3
-
54
-
-
84857033178
-
Measurement of mucosal biomarkers in a Phase 1 trial of intravaginal 3% StarPharma LTD 7013 gel (VivaGel) to assess expanded safety
-
Moscicki AB, Kaul R, Ma Y et al. Measurement of mucosal biomarkers in a Phase 1 trial of intravaginal 3% StarPharma LTD 7013 gel (VivaGel) to assess expanded safety. J. Acquir. Immune Defic. Syndr. 59(2), 134-140 (2012).
-
(2012)
J. Acquir. Immune Defic. Syndr
, vol.59
, Issue.2
, pp. 134-140
-
-
Moscicki, A.B.1
Kaul, R.2
Ma, Y.3
-
55
-
-
84856751344
-
Dendrimers as topical microbicides with activity against HIV
-
Jimnez JL, Pion M, Mata FJDL et al. Dendrimers as topical microbicides with activity against HIV. N. J. Chem. 36(2), 299-309 (2012).
-
(2012)
N. J. Chem
, vol.36
, Issue.2
, pp. 299-309
-
-
Jimnez, J.L.1
Pion, M.2
Mata, F.J.D.L.3
-
56
-
-
84937127376
-
Polyanionic carbosilane dendrimer-conjugated antiviral drugs as efficient microbicides: Recent trends and developments in HIV treatment/therapy
-
Sepulveda-Crespo D, Gomez R, De La Mata FJ, Jimenez JL, Munoz-Fernandez MA. Polyanionic carbosilane dendrimer-conjugated antiviral drugs as efficient microbicides: recent trends and developments in HIV treatment/therapy. Nanomedicine (Lond.) 11(6), 1481-1498 (2015).
-
(2015)
Nanomedicine (Lond.)
, vol.11
, Issue.6
, pp. 1481-1498
-
-
Sepulveda-Crespo, D.1
Gomez, R.2
De La Mata, F.J.3
Jimenez, J.L.4
Munoz-Fernandez, M.A.5
-
57
-
-
84928164425
-
Triple combination of carbosilane dendrimers, tenofovir and maraviroc as potential microbicide to prevent HIV-1 sexual transmission
-
Sepulveda-Crespo D, Sanchez-Rodriguez J, Serramia MJ et al. Triple combination of carbosilane dendrimers, tenofovir and maraviroc as potential microbicide to prevent HIV-1 sexual transmission. Nanomedicine (Lond.) 10(6), 899-914 (2015).
-
(2015)
Nanomedicine (Lond.)
, vol.10
, Issue.6
, pp. 899-914
-
-
Sepulveda-Crespo, D.1
Sanchez-Rodriguez, J.2
Serramia, M.J.3
-
58
-
-
84937109836
-
Prevention vaginally of HIV-1 transmission in humanized BLT mice and mode of antiviral action of polyanionic carbosilane dendrimer G2-S16
-
Seplveda-Crespo D, Serrama MJ, Tager AM et al. Prevention vaginally of HIV-1 transmission in humanized BLT mice and mode of antiviral action of polyanionic carbosilane dendrimer G2-S16. Nanomedicine (Lond.) 11(6), 1299-308 (2015).
-
(2015)
Nanomedicine (Lond.)
, vol.11
, Issue.6
, pp. 1299-1308
-
-
Seplveda-Crespo, D.1
Serrama, M.J.2
Tager, A.M.3
-
59
-
-
84862687804
-
Polymeric nanoparticles affect the intracellular delivery, antiretroviral activity and cytotoxicity of the microbicide drug candidate dapivirine
-
Das Neves J, Michiels J, Arin KK et al. Polymeric nanoparticles affect the intracellular delivery, antiretroviral activity and cytotoxicity of the microbicide drug candidate dapivirine. Pharm. Res. 29(6), 1468-1484 (2012).
-
(2012)
Pharm. Res
, vol.29
, Issue.6
, pp. 1468-1484
-
-
Das Neves, J.1
Michiels, J.2
Arin, K.K.3
-
60
-
-
84884308158
-
Assessing the physical-chemical properties and stability of dapivirineloaded polymeric nanoparticles
-
das Neves J, Amiji M, Bahia MF, Sarmento B. Assessing the physical-chemical properties and stability of dapivirineloaded polymeric nanoparticles. Int. J. Pharm. 456(2), 307-314 (2013).
-
(2013)
Int. J. Pharm
, vol.456
, Issue.2
, pp. 307-314
-
-
Das Neves, J.1
Amiji, M.2
Bahia, M.F.3
Sarmento, B.4
-
61
-
-
84868526145
-
Interactions of microbicide nanoparticles with a simulated vaginal fluid
-
das Neves J, Rocha CM, Goncalves MP et al. Interactions of microbicide nanoparticles with a simulated vaginal fluid. Mol. Pharm. 9(11), 3347-3356 (2012).
-
(2012)
Mol. Pharm
, vol.9
, Issue.11
, pp. 3347-3356
-
-
Das Neves, J.1
Rocha, C.M.2
Goncalves, M.P.3
-
62
-
-
79958792602
-
Formulation of tenofovirloaded functionalized solid lipid nanoparticles intended for HIV prevention
-
Alukda D, Sturgis T, Youan BB. Formulation of tenofovirloaded functionalized solid lipid nanoparticles intended for HIV prevention. J. Pharm. Sci. 100(8), 3345-3356 (2011).
-
(2011)
J. Pharm. Sci
, vol.100
, Issue.8
, pp. 3345-3356
-
-
Alukda, D.1
Sturgis, T.2
Youan, B.B.3
-
63
-
-
80053960975
-
PH-responsive nanoparticles releasing tenofovir intended for the prevention of HIV transmission
-
Zhang T, Sturgis TF, Youan BB. pH-responsive nanoparticles releasing tenofovir intended for the prevention of HIV transmission. Eur. J. Pharm. Biopharm. 79(3), 526-536 (2011).
-
(2011)
Eur. J. Pharm. Biopharm
, vol.79
, Issue.3
, pp. 526-536
-
-
Zhang, T.1
Sturgis, T.F.2
Youan, B.B.3
-
64
-
-
84908879621
-
Comparative biophysical properties of tenofovir-loaded, thiolated and nonthiolated chitosan nanoparticles intended for HIV prevention
-
Meng J, Zhang T, Agrahari V, Ezoulin MJ, Youan BB. Comparative biophysical properties of tenofovir-loaded, thiolated and nonthiolated chitosan nanoparticles intended for HIV prevention. Nanomedicine (Lond.) 9(11), 1595-1612 (2014).
-
(2014)
Nanomedicine (Lond.)
, vol.9
, Issue.11
, pp. 1595-1612
-
-
Meng, J.1
Zhang, T.2
Agrahari, V.3
Ezoulin, M.J.4
Youan, B.B.5
-
65
-
-
84943453074
-
Polymerbased nanocarriers for vaginal drug delivery
-
Epub ahead of print
-
das Neves J, Nunes R, Machado A, Sarmento B. Polymerbased nanocarriers for vaginal drug delivery. Adv. Drug Deliv. Rev. doi:10.1016/j.addr.2014.12.004 (2014) (Epub ahead of print).
-
(2014)
Adv. Drug Deliv. Rev
-
-
Das Neves, J.1
Nunes, R.2
Machado, A.3
Sarmento, B.4
-
66
-
-
84927032988
-
Precise engineering of dapivirineloaded nanoparticles for the development of anti-HIV vaginal microbicides
-
das Neves J, Sarmento B. Precise engineering of dapivirineloaded nanoparticles for the development of anti-HIV vaginal microbicides. Acta Biomater.18, 77-87 (2015).
-
(2015)
Acta Biomater
, vol.18
, pp. 77-87
-
-
Das Neves, J.1
Sarmento, B.2
-
67
-
-
84869212370
-
Development and evaluation of a thermosensitive vaginal gel containing raltegravir+efavirenz loaded nanoparticles for HIV prophylaxis
-
Date AA, Shibata A, Goede M et al. Development and evaluation of a thermosensitive vaginal gel containing raltegravir+efavirenz loaded nanoparticles for HIV prophylaxis. Antiviral. Res. 96(3), 430-436 (2012).
-
(2012)
Antiviral. Res
, vol.96
, Issue.3
, pp. 430-436
-
-
Date, A.A.1
Shibata, A.2
Goede, M.3
-
68
-
-
84940731025
-
Nanoformulations of rilpivirine for topical pericoital and systemic coitus-independent administration efficiently prevent HIV transmission
-
Kovarova M, Council OD, Date AA et al. Nanoformulations of rilpivirine for topical pericoital and systemic coitus-independent administration efficiently prevent HIV transmission. PLoS Pathog. 11(8), e1005075 (2015).
-
(2015)
PLoS Pathog
, vol.11
, Issue.8
, pp. e1005075
-
-
Kovarova, M.1
Council, O.D.2
Date, A.A.3
-
69
-
-
77955510139
-
Protective properties of non-nucleoside reverse transcriptase inhibitor (MC1220) incorporated into liposome against intravaginal challenge of Rhesus macaques with RT-SHIV
-
Caron M, Besson G, Etenna SL et al. Protective properties of non-nucleoside reverse transcriptase inhibitor (MC1220) incorporated into liposome against intravaginal challenge of Rhesus macaques with RT-SHIV. Virology. 405(1), 225-233 (2010).
-
(2011)
Virology
, vol.405
, Issue.1
, pp. 225-233
-
-
Caron, M.1
Besson, G.2
Etenna, S.L.3
-
70
-
-
60149105478
-
Targeted delivery of PSC-RANTES for HIV-1 prevention using biodegradable nanoparticles
-
Ham AS, Cost MR, Sassi AB, Dezzutti CS, Rohan LC. Targeted delivery of PSC-RANTES for HIV-1 prevention using biodegradable nanoparticles. Pharm. Res. 26(3), 502-511 (2009).
-
(2009)
Pharm. Res
, vol.26
, Issue.3
, pp. 502-511
-
-
Ham, A.S.1
Cost, M.R.2
Sassi, A.B.3
Dezzutti, C.S.4
Rohan, L.C.5
-
71
-
-
84974624057
-
Electrospun fibers for microbicide drug delivery
-
. das Neves J, Sarmento B (Eds.) Pan Stanford, Singapore
-
Ball C, Woodrow KA. Electrospun fibers for microbicide drug delivery. In:Drug Delivery and Development of Anti HIV Microbicides . das Neves J, Sarmento B (Eds.) Pan Stanford, Singapore, 459-507 ( 2014).
-
(2014)
Drug Delivery and Development of Anti HIV Microbicides
, pp. 459-507
-
-
Ball, C.1
Woodrow, K.A.2
-
72
-
-
84904252215
-
Biodistribution and pharmacokinetics of dapivirine-loaded nanoparticles after vaginal delivery in mice
-
das Neves J, Arajo F, Andrade F, Amiji M, Bahia MF, Sarmento B. Biodistribution and pharmacokinetics of dapivirine-loaded nanoparticles after vaginal delivery in mice. Pharm. Res. 31(7), 1834-1845 (2014).
-
(2014)
Pharm. Res
, vol.31
, Issue.7
, pp. 1834-1845
-
-
Das Neves, J.1
Arajo, F.2
Andrade, F.3
Amiji, M.4
Bahia, M.F.5
Sarmento, B.6
-
73
-
-
84890120365
-
Electrospun fibers for vaginal anti-HIV drug delivery
-
Blakney AK, Ball C, Krogstad EA, Woodrow KA. Electrospun fibers for vaginal anti-HIV drug delivery. Antiviral. Res. 100(Suppl.), S9-S16 (2013).
-
(2013)
Antiviral. Res
, vol.100
, pp. S9-S16
-
-
Blakney, A.K.1
Ball, C.2
Krogstad, E.A.3
Woodrow, K.A.4
-
74
-
-
84870318366
-
Drugeluting fibers for HIV-1 inhibition and contraception
-
Ball C, Krogstad E, Chaowanachan T, Woodrow KA. Drugeluting fibers for HIV-1 inhibition and contraception. PLoS ONE 7(11), e49792 (2012).
-
(2012)
PLoS ONE
, vol.7
, Issue.11
, pp. e49792
-
-
Ball, C.1
Krogstad, E.2
Chaowanachan, T.3
Woodrow, K.A.4
-
75
-
-
84905396254
-
Electrospun solid dispersions of Maraviroc for rapid intravaginal preexposure prophylaxis of HIV
-
Ball C, Woodrow KA. Electrospun solid dispersions of Maraviroc for rapid intravaginal preexposure prophylaxis of HIV. Antimicrob. Agents Chemother. 58(8), 4855-4865 (2014).
-
(2014)
Antimicrob. Agents Chemother
, vol.58
, Issue.8
, pp. 4855-4865
-
-
Ball, C.1
Woodrow, K.A.2
-
76
-
-
84907226423
-
Manufacturing scale-up of electrospun poly(vinyl alcohol) fibers containing tenofovir for vaginal drug delivery
-
Krogstad EA, Woodrow KA. Manufacturing scale-up of electrospun poly(vinyl alcohol) fibers containing tenofovir for vaginal drug delivery. Int. J. Pharm. 475(1-2), 282-291 (2014).
-
(2014)
Int. J. Pharm
, vol.475
, Issue.1-2
, pp. 282-291
-
-
Krogstad, E.A.1
Woodrow, K.A.2
-
77
-
-
84907681124
-
Formulation and delivery of anti-HIV rectal microbicides: Advances and challenges
-
Nunes R, Sarmento B, das Neves J. Formulation and delivery of anti-HIV rectal microbicides: advances and challenges. J. Control. Release 194, 278-294 (2014).
-
(2014)
J. Control. Release
, vol.194
, pp. 278-294
-
-
Nunes, R.1
Sarmento, B.2
Das Neves, J.3
-
78
-
-
84055217599
-
Nanosystem formulations for rectal microbicides: A call for more research
-
Sarmento B, das Neves J. Nanosystem formulations for rectal microbicides: a call for more research. Ther. Deliv. 3(1), 1-4 (2012).
-
(2012)
Ther. Deliv
, vol.3
, Issue.1
, pp. 1-4
-
-
Sarmento, B.1
Das Neves, J.2
-
79
-
-
84879736868
-
Vitro and ex vivo evaluation of polymeric nanoparticles for vaginal and rectal delivery of the anti-HIV drug dapivirine
-
das Neves J, Arajo F, Andrade F et al. In vitro and ex vivo evaluation of polymeric nanoparticles for vaginal and rectal delivery of the anti-HIV drug dapivirine. Mol.Pharm. 10(7), 2793-2807 (2013).
-
(2013)
Mol.Pharm
, vol.10
, Issue.7
, pp. 2793-2807
-
-
Das Neves, J.1
Arajo, F.2
Andrade, F.3
-
80
-
-
84860244308
-
Nanotechnology and the treatment of HIV infection
-
Parboosing R, Maguire GE, Govender P, Kruger HG. Nanotechnology and the treatment of HIV infection. Viruses 4(4), 488-520 (2012)
-
(2012)
Viruses
, vol.4
, Issue.4
, pp. 488-520
-
-
Parboosing, R.1
Maguire, G.E.2
Govender, P.3
Kruger, H.G.4
-
81
-
-
84930902992
-
HIV treatment 2020: What will it look like?
-
Gulick R. HIV treatment 2020: what will it look like? J. Int. AIDS Soc. 17(4 Suppl. 3), 19528 (2014).
-
(2014)
J. Int. AIDS Soc
, vol.17
, Issue.4
, pp. 19528
-
-
Gulick, R.1
|